acetovanillone has been researched along with Pregnancy in 24 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated whether hypertension induced by maternal lipopolysaccharide (LPS) administration during gestation is linked to peripheral vascular and renal hemodynamic regulation, through angiotensin II → NADPH-oxidase signalling, and whether these changes are directly linked to intrauterine oxidative stress." | 3.88 | Oxidative stress induced by prenatal LPS leads to endothelial dysfunction and renal haemodynamic changes through angiotensin II/NADPH oxidase pathway: Prevention by early treatment with α-tocopherol. ( Aires, RS; Cabral, EV; de Queiroz, DB; Farias, JS; Lima-Filho, MM; Paixão, AD; Ribeiro, VS; Sant'Helena, BRM; Santos-Rocha, J; Vieira, LD; Xavier, FE, 2018) |
| "The present findings suggest that antenatal nicotine exposure results in the programming of heightened oxidative stress and vascular hypertensive reactivity via a Nox2-dependent mechanism, leading to an increased risk of hypertension in adult offspring." | 3.77 | Antenatal nicotine induces heightened oxidative stress and vascular dysfunction in rat offspring. ( Huang, X; Xiao, D; Yang, S; Zhang, L, 2011) |
| " More recently it has been suggested that uric acid may directly contribute to pathological cell signaling events involved in disease progression as well as maternal and fetal pregnancy outcomes including fetal growth restriction." | 3.75 | Uric acid inhibits placental system A amino acid uptake. ( Bainbridge, SA; Roberts, JM; von Versen-Höynck, F, 2009) |
| "Preeclampsia was characterized by excessive thrombin generation in placentas and previous researches showed that thrombin could enhance soluble Fms-like tyrosine kinase 1 (sFlt-1) expression in first trimester trophoblasts." | 1.42 | Activation of PAR-1/NADPH oxidase/ROS signaling pathways is crucial for the thrombin-induced sFlt-1 production in extravillous trophoblasts: possible involvement in the pathogenesis of preeclampsia. ( Chen, JH; Hang, LL; Huang, QT; Liu, SS; Zhong, M, 2015) |
| "Women with preeclampsia had significantly increased circulating (P=0." | 1.40 | CD4+ T cells are important mediators of oxidative stress that cause hypertension in response to placental ischemia. ( Chatman, K; Cornelius, DC; Heath, J; LaMarca, B; Moseley, J; Scott, J; Wallace, K, 2014) |
| " These data suggest that multiparity induces endothelial dysfunction through decreased NO bioavailability and increased reactive oxygen species formation." | 1.35 | Role of oxidative stress in multiparity-induced endothelial dysfunction. ( Cena, J; Kaufman, S; Schulz, R; Tawfik, HE, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 15 (62.50) | 24.3611 |
| 2020's | 5 (20.83) | 2.80 |
| Authors | Studies |
|---|---|
| Tayman, C | 1 |
| Çakır, U | 1 |
| Akduman, H | 1 |
| Karabulut, Ş | 1 |
| Çağlayan, M | 1 |
| Cipolla, MJ | 1 |
| Tremble, S | 1 |
| DeLance, N | 1 |
| Allison, D | 1 |
| Johnson, AC | 1 |
| Saha, PS | 3 |
| Knecht, TM | 3 |
| Arrick, DM | 3 |
| Watt, MJ | 3 |
| Scholl, JL | 3 |
| Mayhan, WG | 5 |
| Timóteo-Ferreira, F | 1 |
| Mendes, S | 1 |
| Rocha, NA | 1 |
| Matos, L | 2 |
| Rodrigues, AR | 1 |
| Almeida, H | 2 |
| Silva, E | 2 |
| Liu, T | 1 |
| Zheng, W | 1 |
| Wang, L | 2 |
| Zhang, Y | 1 |
| Sha, H | 1 |
| Ma, Y | 1 |
| Tong, Y | 1 |
| Zhao, J | 1 |
| Qin, F | 1 |
| Cananzi, SG | 2 |
| Aras-López, R | 1 |
| Almeida, L | 1 |
| Andreu-Fernández, V | 1 |
| Tovar, J | 1 |
| Martínez, L | 1 |
| Lai, Q | 1 |
| Xiang, W | 1 |
| Li, Q | 1 |
| Zhang, H | 2 |
| Li, Y | 1 |
| Zhu, G | 1 |
| Xiong, C | 1 |
| Jin, L | 1 |
| Vieira, LD | 1 |
| Farias, JS | 1 |
| de Queiroz, DB | 1 |
| Cabral, EV | 1 |
| Lima-Filho, MM | 1 |
| Sant'Helena, BRM | 1 |
| Aires, RS | 1 |
| Ribeiro, VS | 1 |
| Santos-Rocha, J | 1 |
| Xavier, FE | 1 |
| Paixão, AD | 1 |
| Min, S | 1 |
| Kim, OJ | 1 |
| Bae, J | 1 |
| Chung, TN | 1 |
| Huang, QT | 3 |
| Wang, SS | 1 |
| Zhang, M | 2 |
| Huang, LP | 2 |
| Tian, JW | 1 |
| Yu, YH | 2 |
| Wang, ZJ | 2 |
| Zhong, M | 3 |
| Liang, WZ | 1 |
| Hang, LL | 2 |
| Gao, YF | 1 |
| Wallace, K | 1 |
| Cornelius, DC | 1 |
| Scott, J | 1 |
| Heath, J | 1 |
| Moseley, J | 1 |
| Chatman, K | 1 |
| LaMarca, B | 1 |
| Chen, JH | 1 |
| Liu, SS | 1 |
| Soares, AI | 1 |
| Costa, F | 1 |
| Castro, JP | 1 |
| Zhu, X | 1 |
| Gao, Q | 1 |
| Tu, Q | 1 |
| Zhong, Y | 1 |
| Zhu, D | 1 |
| Mao, C | 1 |
| Xu, Z | 1 |
| Sun, XR | 1 |
| Wang, J | 1 |
| Zhang, ZZ | 1 |
| Zhao, HT | 1 |
| Li, HH | 1 |
| Ji, MH | 1 |
| Li, KY | 1 |
| Yang, JJ | 1 |
| Tawfik, HE | 1 |
| Cena, J | 1 |
| Schulz, R | 1 |
| Kaufman, S | 1 |
| Bainbridge, SA | 1 |
| von Versen-Höynck, F | 1 |
| Roberts, JM | 1 |
| Xiao, D | 1 |
| Huang, X | 1 |
| Yang, S | 1 |
| Zhang, L | 1 |
| Franco, Mdo C | 1 |
| Akamine, EH | 2 |
| Di Marco, GS | 1 |
| Casarini, DE | 1 |
| Fortes, ZB | 2 |
| Tostes, RC | 2 |
| Carvalho, MH | 2 |
| Nigro, D | 2 |
| Franco, MC | 1 |
| Rebouças, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Antioxidant Activity of Lutein/Zeaxanthin Early Administered to Premature Newborns[NCT03340103] | 0 participants (Actual) | Interventional | 2018-10-11 | Withdrawn (stopped due to Recruitment was not possible) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
24 other studies available for acetovanillone and Pregnancy
| Article | Year |
|---|---|
The therapeutic effect of Apocynin against hyperoxy and Inflammation-Induced lung injury.
Topics: Acetophenones; Animals; Animals, Newborn; Female; Hyperoxia; Lung; Lung Injury; Pneumonia; Pregnancy | 2021 |
Treatment with apocynin selectively restores hippocampal arteriole function and seizure-induced hyperemia in a model of preeclampsia.
Topics: Acetophenones; Animals; Arterioles; Elastin; Female; Hippocampus; Humans; Hyperemia; Pre-Eclampsia; | 2022 |
Prenatal exposure to alcohol impairs responses of cerebral arterioles to activation of potassium channels: Role of oxidative stress.
Topics: Adenosine Triphosphate; Animals; Arterioles; Ethanol; Female; Humans; Iloprost; Large-Conductance Ca | 2023 |
Prenatal exposure to alcohol impairs responses of cerebral arterioles to activation of potassium channels: Role of oxidative stress.
Topics: Adenosine Triphosphate; Animals; Arterioles; Ethanol; Female; Humans; Iloprost; Large-Conductance Ca | 2023 |
Prenatal exposure to alcohol impairs responses of cerebral arterioles to activation of potassium channels: Role of oxidative stress.
Topics: Adenosine Triphosphate; Animals; Arterioles; Ethanol; Female; Humans; Iloprost; Large-Conductance Ca | 2023 |
Prenatal exposure to alcohol impairs responses of cerebral arterioles to activation of potassium channels: Role of oxidative stress.
Topics: Adenosine Triphosphate; Animals; Arterioles; Ethanol; Female; Humans; Iloprost; Large-Conductance Ca | 2023 |
Apocynin Dietary Supplementation Delays Mouse Ovarian Ageing.
Topics: Acetophenones; Aged; Animals; Dietary Supplements; Female; Humans; Mice; Ovary; Pregnancy; Reproduct | 2019 |
TLR4/NF-κB Signaling Pathway Participates in the Protective Effects of Apocynin on Gestational Diabetes Mellitus Induced Placental Oxidative Stress and Inflammation.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Antioxidants; Diabetes, Gestational; Female; Infla | 2020 |
Apocynin inhibits placental TLR4/NF-κB signaling pathway and ameliorates preeclampsia-like symptoms in rats.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Down-Regulation; Fe | 2020 |
In utero exposure to alcohol alters reactivity of cerebral arterioles.
Topics: Acetophenones; Adenosine Diphosphate; Animals; Arterioles; Cerebral Cortex; Chronic Disease; Ethanol | 2019 |
Anti-oxidants correct disturbance of redox enzymes in the hearts of rat fetuses with congenital diaphragmatic hernia.
Topics: Acetophenones; Animals; Antioxidants; Catalase; Catechin; Disease Models, Animal; Female; Glutathion | 2018 |
Oxidative stress in granulosa cells contributes to poor oocyte quality and IVF-ET outcomes in women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Acetophenones; Adult; Apoptosis; Embryo Transfer; Female; Fertilization in Vi | 2018 |
Oxidative stress induced by prenatal LPS leads to endothelial dysfunction and renal haemodynamic changes through angiotensin II/NADPH oxidase pathway: Prevention by early treatment with α-tocopherol.
Topics: Acetophenones; alpha-Tocopherol; Angiotensin II; Animals; Antioxidants; Blood Pressure; Female; Hemo | 2018 |
Effect of Pretreatment with the NADPH Oxidase Inhibitor Apocynin on the Therapeutic Efficacy of Human Placenta-Derived Mesenchymal Stem Cells in Intracerebral Hemorrhage.
Topics: Acetophenones; Animals; Cells, Cultured; Cerebral Hemorrhage; Enzyme Inhibitors; Female; Humans; Mal | 2018 |
In Utero Exposure to Alcohol Impairs Reactivity of Cerebral Arterioles and Increases Susceptibility of the Brain to Damage Following Ischemia/Reperfusion in Adulthood.
Topics: Acetophenones; Adenosine Diphosphate; Animals; Arterioles; Brain; Enzyme Inhibitors; Ethanol; Excita | 2019 |
Advanced oxidation protein products enhances soluble Fms-like tyrosine kinase 1 expression in trophoblasts: a possible link between oxidative stress and preeclampsia.
Topics: Acetophenones; Advanced Oxidation Protein Products; Cell Line; Female; Humans; Oxidative Stress; Pla | 2013 |
Advanced glycation end products as an upstream molecule triggers ROS-induced sFlt-1 production in extravillous trophoblasts: a novel bridge between oxidative stress and preeclampsia.
Topics: Acetophenones; Cell Line; Enzyme Inhibitors; Female; Gene Expression Regulation, Developmental; Glyc | 2013 |
CD4+ T cells are important mediators of oxidative stress that cause hypertension in response to placental ischemia.
Topics: Acetophenones; Adolescent; Adult; Animals; Antioxidants; CD4-Positive T-Lymphocytes; Cells, Cultured | 2014 |
Activation of PAR-1/NADPH oxidase/ROS signaling pathways is crucial for the thrombin-induced sFlt-1 production in extravillous trophoblasts: possible involvement in the pathogenesis of preeclampsia.
Topics: Acetophenones; Cell Line; Enzyme-Linked Immunosorbent Assay; Female; Humans; NADPH Oxidases; Pre-Ecl | 2015 |
Antioxidant Supplementation Modulates Age-Related Placental Bed Morphology and Reproductive Outcome in Mice.
Topics: Acetophenones; Aging; Animals; Antioxidants; Cyclic N-Oxides; Decidua; Female; Fetus; Litter Size; M | 2015 |
Prenatal hypoxia enhanced angiotensin II-mediated vasoconstriction via increased oxidative signaling in fetal rats.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Body Weight; Cyclic N-Oxides; | 2016 |
Reactive Oxygen Species-mediated Loss of Phenotype of Parvalbumin Interneurons Contributes to Long-term Cognitive Impairments After Repeated Neonatal Ketamine Exposures.
Topics: Acetophenones; Animals; Anxiety; Brain; Cognitive Dysfunction; Cohort Studies; Disease Models, Anima | 2016 |
Role of oxidative stress in multiparity-induced endothelial dysfunction.
Topics: Acetophenones; Acetylcholine; Animals; Aorta, Thoracic; Coronary Vessels; Dose-Response Relationship | 2008 |
Uric acid inhibits placental system A amino acid uptake.
Topics: Acetophenones; Adult; Amino Acid Transport System A; Amino Acids; Antioxidants; Cell Survival; Chori | 2009 |
Antenatal nicotine induces heightened oxidative stress and vascular dysfunction in rat offspring.
Topics: Acetophenones; Angiotensin II; Animals; Aorta; Blotting, Western; Cyclic N-Oxides; Dose-Response Rel | 2011 |
NADPH oxidase and enhanced superoxide generation in intrauterine undernourished rats: involvement of the renin-angiotensin system.
Topics: Acetophenones; Angiotensin II; Animals; Cyclooxygenase Inhibitors; Diclofenac; Enzyme Inhibitors; Fe | 2003 |
Long-term effects of intrauterine malnutrition on vascular function in female offspring: implications of oxidative stress.
Topics: Acetophenones; Animals; Animals, Newborn; Arterioles; Blood Pressure; Drug Interactions; Endothelium | 2007 |