acetovanillone has been researched along with Inflammation in 41 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The current study aimed to investigate the effectiveness of carvedilol (CV), Acetovanillone (ACET), and their combination for ameliorating cadmium (Cd)-induced oxidative stress, inflammation, and necroptosis." | 8.31 | Acetovanillone augmented the cardioprotective effect of carvedilol against cadmium-induced heart injury via suppression of oxidative stress and inflammation signaling pathways. ( Ahmed, LK; Ali, FEM; Bakr, AG; El-Shoura, EAM; Hassanein, EHM, 2023) |
| " Rehmannia complex (Reh) a famous prescription in China and the triterpene acids (TTA) isolated from Reh may relieve the isoproterenol (ISO) induced chronic inflammation in the brain, compared with APO." | 7.80 | Isoproterenol induced stressful reactions in the brain are characterized by inflammation due to activation of NADPH oxidase and ER stress: attenuated by Apocynin, Rehmannia complex and Triterpene acids. ( Cong, XD; Dai, DZ; Dai, Y; Du, RH; Li, Y; Mo, GL, 2014) |
| " Despite comparable hypotensive effects between valsartan and hydralazine in salt-loaded SHRSP, valsartan reduced cerebral NADPH oxidase activity and ROS more than hydralazine being accompanied by more prevention of stroke by valsartan than hydralazine." | 7.74 | Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation. ( Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tamamaki, N; Tokutomi, Y; Yamamoto, E, 2008) |
| " The current study aimed to investigate the effectiveness of carvedilol (CV), Acetovanillone (ACET), and their combination for ameliorating cadmium (Cd)-induced oxidative stress, inflammation, and necroptosis." | 4.31 | Acetovanillone augmented the cardioprotective effect of carvedilol against cadmium-induced heart injury via suppression of oxidative stress and inflammation signaling pathways. ( Ahmed, LK; Ali, FEM; Bakr, AG; El-Shoura, EAM; Hassanein, EHM, 2023) |
| "In the histological examination, on the 3rd, 7th and 21st days, inflammation was found to be reduced in the groups given taurine and apocynin on the 3rd day." | 4.12 | Effects of taurine and apocynin on the zone of stasis. ( Abbas Ali Noma, S; Fırat, C; Öcük, Ö; Özhan, O; Parlakpınar, H; Ulu, A; Vardı, N; Yıldız, A, 2022) |
| " Rehmannia complex (Reh) a famous prescription in China and the triterpene acids (TTA) isolated from Reh may relieve the isoproterenol (ISO) induced chronic inflammation in the brain, compared with APO." | 3.80 | Isoproterenol induced stressful reactions in the brain are characterized by inflammation due to activation of NADPH oxidase and ER stress: attenuated by Apocynin, Rehmannia complex and Triterpene acids. ( Cong, XD; Dai, DZ; Dai, Y; Du, RH; Li, Y; Mo, GL, 2014) |
| " Despite comparable hypotensive effects between valsartan and hydralazine in salt-loaded SHRSP, valsartan reduced cerebral NADPH oxidase activity and ROS more than hydralazine being accompanied by more prevention of stroke by valsartan than hydralazine." | 3.74 | Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation. ( Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tamamaki, N; Tokutomi, Y; Yamamoto, E, 2008) |
| " However, pharmaceutical experts face significant hurdles due to the limited bioavailability and quick elimination of APO." | 1.91 | Apocynin and its chitosan nanoparticles attenuated cisplatin-induced multiorgan failure: Synthesis, characterization, and biological evaluation. ( Bakhite, EA; Hassanein, EHM; Mahmoud, NA; Sayed, AM; Shaltout, ES, 2023) |
| "Chronic obstructive pulmonary disease (COPD) is a major, incurable respiratory condition that is primarily caused by cigarette smoking (CS)." | 1.91 | Cigarette smoke-induced pulmonary impairment is associated with social recognition memory impairments and alterations in microglial profiles within the suprachiasmatic nucleus of the hypothalamus. ( Akhtar, A; Alateeq, R; Bozinovski, S; Brassington, K; Chan, SMH; De Luca, SN; Dobric, A; Mou, K; Seow, HJ; Vlahos, R; Wang, H, 2023) |
| " The time-response and dose-response study showed that apocynin significantly influenced the relative expression of chosen genes (IL-6, IL-8, TNF, PPAR-γ, TSLP, and CD59)." | 1.51 | Inhibition of NADPH Oxidase-Derived Reactive Oxygen Species Decreases Expression of Inflammatory Cytokines in A549 Cells. ( Kowalczyk, T; Pawliczak, R; Sitarek, P; Skała, E; Wieczfinska, J, 2019) |
| " Mito-Apo showed excellent brain bioavailability and also markedly attenuated MPTP-induced oxidative markers in the substantia nigra (SN)." | 1.43 | Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson's Disease. ( Anantharam, V; Brenza, T; Ghosh, A; Harischandra, DS; Jin, H; Joseph, J; Kalyanaraman, B; Kanthasamy, A; Kanthasamy, AG; Langley, MR; Narasimhan, B; Neal, ML, 2016) |
| "Chemical burns are a major cause of corneal injury." | 1.43 | Involvement of NADPH oxidases in alkali burn-induced corneal injury. ( Chen, YY; Gu, XJ; Han, XJ; Li, JM; Liu, QP; Liu, X; Xu, M; Yi, JL; Zhao, Y, 2016) |
| "Ozone is an environmental pollutant with potent oxidizing properties." | 1.30 | Proliferation of airway epithelium after ozone exposure: effect of apocynin and dexamethasone. ( Barnes, PJ; Chung, KF; Haddad, EB; Koto, H; Lamb, NJ; Lynch, OT; Quinlan, GJ; Salmon, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.44) | 18.2507 |
| 2000's | 9 (21.95) | 29.6817 |
| 2010's | 22 (53.66) | 24.3611 |
| 2020's | 9 (21.95) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Öcük, Ö | 1 |
| Fırat, C | 1 |
| Yıldız, A | 1 |
| Vardı, N | 1 |
| Ulu, A | 1 |
| Abbas Ali Noma, S | 1 |
| Parlakpınar, H | 1 |
| Özhan, O | 1 |
| Mahmoud, NA | 1 |
| Hassanein, EHM | 3 |
| Bakhite, EA | 1 |
| Shaltout, ES | 1 |
| Sayed, AM | 2 |
| De Luca, SN | 1 |
| Chan, SMH | 1 |
| Dobric, A | 1 |
| Wang, H | 1 |
| Seow, HJ | 1 |
| Brassington, K | 1 |
| Mou, K | 1 |
| Alateeq, R | 1 |
| Akhtar, A | 1 |
| Bozinovski, S | 1 |
| Vlahos, R | 1 |
| Bakr, AG | 1 |
| El-Shoura, EAM | 1 |
| Ahmed, LK | 1 |
| Ali, FEM | 2 |
| Park, YJ | 1 |
| Gil, TY | 1 |
| Jin, BR | 1 |
| Cha, YY | 1 |
| An, HJ | 1 |
| Ghio, AJ | 1 |
| Soukup, JM | 1 |
| Stonehuerner, J | 1 |
| Tong, H | 1 |
| Richards, J | 1 |
| Gilmour, MI | 1 |
| Madden, MC | 1 |
| Shen, Z | 1 |
| Kantrow, SP | 1 |
| Wieczfinska, J | 1 |
| Sitarek, P | 1 |
| Skała, E | 1 |
| Kowalczyk, T | 1 |
| Pawliczak, R | 2 |
| Yang, X | 2 |
| Zhao, K | 1 |
| Deng, W | 1 |
| Zhao, L | 1 |
| Jin, H | 2 |
| Mei, F | 1 |
| Zhou, Y | 2 |
| Li, M | 3 |
| Wang, W | 1 |
| Liu, T | 1 |
| Zheng, W | 1 |
| Wang, L | 2 |
| Zhang, Y | 2 |
| Cross, AL | 1 |
| Hawkes, J | 1 |
| Wright, HL | 1 |
| Moots, RJ | 1 |
| Edwards, SW | 1 |
| Omar, ZMM | 1 |
| Rashwan, EK | 1 |
| Mohammedsaleh, ZM | 1 |
| Abd El-Ghafar, OAM | 1 |
| Rahman, MM | 1 |
| Muse, AY | 1 |
| Khan, DMIO | 1 |
| Ahmed, IH | 1 |
| Subhan, N | 1 |
| Reza, HM | 1 |
| Alam, MA | 1 |
| Nahar, L | 1 |
| Sarker, SD | 1 |
| Bhatt, NP | 1 |
| Park, JY | 2 |
| Lee, HJ | 1 |
| Kim, SS | 1 |
| Kwon, YS | 1 |
| Chun, W | 3 |
| Zhang, B | 1 |
| Bailey, WM | 1 |
| McVicar, AL | 1 |
| Stewart, AN | 1 |
| Veldhorst, AK | 1 |
| Gensel, JC | 1 |
| Hwang, YJ | 2 |
| Nam, SJ | 2 |
| Kim, SI | 1 |
| Park, SC | 2 |
| Kang, CD | 2 |
| Lee, SJ | 2 |
| Yan, L | 1 |
| Liu, S | 2 |
| Wang, C | 1 |
| Wang, F | 1 |
| Song, Y | 1 |
| Yan, N | 1 |
| Xi, S | 1 |
| Liu, Z | 1 |
| Sun, G | 1 |
| Ferreira, AP | 1 |
| Rodrigues, FS | 1 |
| Della-Pace, ID | 1 |
| Mota, BC | 1 |
| Oliveira, SM | 1 |
| Velho Gewehr, Cde C | 1 |
| Bobinski, F | 1 |
| de Oliveira, CV | 1 |
| Brum, JS | 1 |
| Oliveira, MS | 1 |
| Furian, AF | 1 |
| de Barros, CS | 1 |
| Ferreira, J | 1 |
| Santos, AR | 1 |
| Fighera, MR | 1 |
| Royes, LF | 1 |
| Mo, GL | 1 |
| Li, Y | 1 |
| Du, RH | 1 |
| Dai, DZ | 1 |
| Cong, XD | 1 |
| Dai, Y | 1 |
| Ding, Z | 1 |
| Wang, X | 1 |
| Deng, X | 1 |
| Fan, Y | 1 |
| Sun, C | 1 |
| Wang, Y | 1 |
| Mehta, JL | 1 |
| Wei, DD | 1 |
| Lin, XH | 1 |
| Wang, HC | 1 |
| Wang, B | 1 |
| Bai, CY | 1 |
| Wang, YQ | 1 |
| Li, GE | 1 |
| Ren, XQ | 1 |
| Chen, W | 1 |
| Li, Z | 1 |
| Guo, Y | 1 |
| Zhang, Z | 1 |
| Luo, G | 1 |
| Liao, W | 1 |
| Li, C | 1 |
| Chen, L | 1 |
| Sheng, P | 1 |
| Lin, AH | 1 |
| Liu, MH | 1 |
| Ko, HK | 1 |
| Perng, DW | 1 |
| Lee, TS | 1 |
| Kou, YR | 1 |
| Ghosh, A | 1 |
| Langley, MR | 1 |
| Harischandra, DS | 1 |
| Neal, ML | 1 |
| Anantharam, V | 1 |
| Joseph, J | 1 |
| Brenza, T | 1 |
| Narasimhan, B | 1 |
| Kanthasamy, A | 1 |
| Kalyanaraman, B | 1 |
| Kanthasamy, AG | 1 |
| Gu, XJ | 1 |
| Liu, X | 1 |
| Chen, YY | 1 |
| Zhao, Y | 1 |
| Xu, M | 1 |
| Han, XJ | 1 |
| Liu, QP | 1 |
| Yi, JL | 1 |
| Li, JM | 1 |
| Park, JM | 1 |
| Choi, DH | 1 |
| Nam, YJ | 1 |
| Kim, A | 1 |
| Sohn, DS | 1 |
| Lee, CS | 1 |
| Liu, ZH | 1 |
| Dai, DP | 1 |
| Ding, FH | 1 |
| Pan, WQ | 1 |
| Fang, YH | 1 |
| Zhang, Q | 1 |
| Yang, P | 1 |
| Wang, XQ | 1 |
| Shen, Y | 1 |
| Wang, LJ | 1 |
| Yan, XX | 1 |
| He, YH | 1 |
| Yang, K | 1 |
| Zhang, RY | 1 |
| Shen, WF | 1 |
| Chen, Y | 1 |
| Lu, L | 1 |
| Qin, YY | 1 |
| Feng, X | 1 |
| Wang, J | 1 |
| Cao, L | 1 |
| Shen, XK | 1 |
| Chen, J | 1 |
| Sun, M | 1 |
| Sheng, R | 1 |
| Han, F | 1 |
| Qin, ZH | 1 |
| Yamamoto, E | 1 |
| Tamamaki, N | 1 |
| Nakamura, T | 1 |
| Kataoka, K | 1 |
| Tokutomi, Y | 1 |
| Dong, YF | 1 |
| Fukuda, M | 1 |
| Matsuba, S | 1 |
| Ogawa, H | 1 |
| Kim-Mitsuyama, S | 1 |
| Tian, N | 1 |
| Moore, RS | 1 |
| Phillips, WE | 1 |
| Lin, L | 1 |
| Braddy, S | 1 |
| Pryor, JS | 1 |
| Stockstill, RL | 1 |
| Hughson, MD | 1 |
| Manning, RD | 1 |
| Stefanska, J | 1 |
| Chen, H | 1 |
| Song, YS | 1 |
| Chan, PH | 1 |
| Kielland, A | 1 |
| Blom, T | 1 |
| Nandakumar, KS | 1 |
| Holmdahl, R | 1 |
| Blomhoff, R | 1 |
| Carlsen, H | 1 |
| Bitar, MS | 1 |
| Ayed, AK | 1 |
| Abdel-Halim, SM | 1 |
| Isenovic, ER | 1 |
| Al-Mulla, F | 1 |
| Freidja, ML | 1 |
| Toutain, B | 1 |
| Caillon, A | 1 |
| Desquiret, V | 1 |
| Lambert, D | 1 |
| Loufrani, L | 1 |
| Procaccio, V | 1 |
| Henrion, D | 1 |
| Barbieri, SS | 1 |
| Cavalca, V | 1 |
| Eligini, S | 1 |
| Brambilla, M | 1 |
| Caiani, A | 1 |
| Tremoli, E | 1 |
| Colli, S | 1 |
| Hougee, S | 1 |
| Hartog, A | 1 |
| Sanders, A | 1 |
| Graus, YM | 1 |
| Hoijer, MA | 1 |
| Garssen, J | 1 |
| van den Berg, WB | 1 |
| van Beuningen, HM | 1 |
| Smit, HF | 1 |
| Lin, FY | 1 |
| Chen, YH | 1 |
| Tasi, JS | 1 |
| Chen, JW | 1 |
| Yang, TL | 1 |
| Wang, HJ | 1 |
| Li, CY | 1 |
| Chen, YL | 1 |
| Lin, SJ | 1 |
| Lu, LS | 1 |
| Wu, CC | 1 |
| Hung, LM | 1 |
| Chiang, MT | 1 |
| Lin, CT | 1 |
| Lin, CW | 1 |
| Su, MJ | 1 |
| Salmon, M | 1 |
| Koto, H | 1 |
| Lynch, OT | 1 |
| Haddad, EB | 1 |
| Lamb, NJ | 1 |
| Quinlan, GJ | 1 |
| Barnes, PJ | 1 |
| Chung, KF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Impact of PCSK9 Inhibitors on Coronary Microvascular Dysfunction in Patients With Atherosclerotic Cardiovascular Disease Proved by Myocardial Ischemia and Needing Coronarography : a Monocentric, Prospective, Randomized and Open-label Phase II Tr[NCT04338165] | Phase 2 | 66 participants (Anticipated) | Interventional | 2021-01-08 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for acetovanillone and Inflammation
| Article | Year |
|---|---|
Apocynin: molecular aptitudes.
Topics: Acetophenones; Animals; Arteriosclerosis; Asthma; Cartilage; Cyclooxygenase 2; Free Radical Scavenge | 2008 |
40 other studies available for acetovanillone and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Effects of taurine and apocynin on the zone of stasis.
Topics: Animals; Antioxidants; Burns; Disease Models, Animal; Inflammation; Rats; Rats, Sprague-Dawley; Taur | 2022 |
Apocynin and its chitosan nanoparticles attenuated cisplatin-induced multiorgan failure: Synthesis, characterization, and biological evaluation.
Topics: Animals; Antioxidants; Chitosan; Cisplatin; Inflammation; Nanoparticles; Oxidative Stress; Rats | 2023 |
Cigarette smoke-induced pulmonary impairment is associated with social recognition memory impairments and alterations in microglial profiles within the suprachiasmatic nucleus of the hypothalamus.
Topics: Adult; Animals; Cigarette Smoking; Dimethyl Sulfoxide; Humans; Hypothalamus; Inflammation; Lung; Mal | 2023 |
Acetovanillone augmented the cardioprotective effect of carvedilol against cadmium-induced heart injury via suppression of oxidative stress and inflammation signaling pathways.
Topics: Animals; Antioxidants; Cadmium; Carvedilol; Heart Injuries; Inflammation; NADPH Oxidases; NF-E2-Rela | 2023 |
Apocynin alleviates weight gain and obesity-induced adipose tissue inflammation in high-fat diet-fed C57BL/6 mice.
Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Diet, High-Fat; Inflammation; Mice; Mice, Inbred C57BL; Obesi | 2023 |
Quartz Disrupts Iron Homeostasis in Alveolar Macrophages To Impact a Pro-Inflammatory Effect.
Topics: Acetophenones; Animals; Cell Line, Tumor; Cytokines; Enzyme Inhibitors; Ferric Compounds; Ferritins; | 2019 |
Inhibition of NADPH Oxidase-Derived Reactive Oxygen Species Decreases Expression of Inflammatory Cytokines in A549 Cells.
Topics: A549 Cells; Acetophenones; Cytokines; Humans; Inflammation; NADPH Oxidases; Oxidative Stress; PPAR g | 2019 |
Apocynin Attenuates Acute Kidney Injury and Inflammation in Rats with Acute Hypertriglyceridemic Pancreatitis.
Topics: Acetophenones; Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Gene | 2020 |
TLR4/NF-κB Signaling Pathway Participates in the Protective Effects of Apocynin on Gestational Diabetes Mellitus Induced Placental Oxidative Stress and Inflammation.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Antioxidants; Diabetes, Gestational; Female; Infla | 2020 |
APPA (apocynin and paeonol) modulates pathological aspects of human neutrophil function, without supressing antimicrobial ability, and inhibits TNFα expression and signalling.
Topics: Acetophenones; Anti-Inflammatory Agents; Apoptosis; Cells, Cultured; Cytokines; Dose-Response Relati | 2020 |
Regulation of Keap-1/Nrf2/AKT and iNOS/NF-κB/TLR4 signals by apocynin abrogated methotrexate-induced testicular toxicity: Mechanistic insights and computational pharmacological analysis.
Topics: Acetophenones; Animals; Antioxidants; Biomarkers; Inflammation; Interleukin-6; Kelch-Like ECH-Associ | 2021 |
Apocynin prevented inflammation and oxidative stress in carbon tetra chloride induced hepatic dysfunction in rats.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carbon Tetrachloride; | 2017 |
Apocynin protects mesangial cells from lipopolysaccharide-induced inflammation by exerting heme oxygenase 1-mediated monocyte chemoattractant protein-1 suppression.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Cell Line; Chemokine CCL2; Cyclooxygenase 2; Gene | 2017 |
Reducing age-dependent monocyte-derived macrophage activation contributes to the therapeutic efficacy of NADPH oxidase inhibition in spinal cord injury.
Topics: Acetophenones; Age Factors; Animals; Disease Models, Animal; Female; Inflammation; Macrophage Activa | 2019 |
Anti-inflammatory effects of apocynin on dextran sulfate sodium-induced mouse colitis model.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Colitis; Colon; Cytokines; Dextran Sulfate; Diseas | 2019 |
JNK and NADPH oxidase involved in fluoride-induced oxidative stress in BV-2 microglia cells.
Topics: Acetophenones; Animals; Anthracenes; Antioxidants; Cell Line; Cell Survival; Enzyme Inhibitors; Enzy | 2013 |
The effect of NADPH-oxidase inhibitor apocynin on cognitive impairment induced by moderate lateral fluid percussion injury: role of inflammatory and oxidative brain damage.
Topics: Acetophenones; Animals; Brain Injuries; Cognition Disorders; Cytokines; Dyskinesia, Drug-Induced; En | 2013 |
Isoproterenol induced stressful reactions in the brain are characterized by inflammation due to activation of NADPH oxidase and ER stress: attenuated by Apocynin, Rehmannia complex and Triterpene acids.
Topics: Acetophenones; Animals; Brain; Cells, Cultured; Endoplasmic Reticulum Stress; Enzyme Activation; Inf | 2014 |
Hemodynamic shear stress via ROS modulates PCSK9 expression in human vascular endothelial and smooth muscle cells and along the mouse aorta.
Topics: Acetophenones; Animals; Antioxidants; Aorta; Endothelium, Vascular; Hemodynamics; Humans; Inflammati | 2015 |
[Apocynin relieves inflammation in dextran sulfate sodium-induced ulcerative colitis mice: the role of NOXs-ROS-p38MAPK pathway].
Topics: Acetophenones; Animals; Colitis, Ulcerative; Cytokines; Dextran Sulfate; Inflammation; MAP Kinase Si | 2015 |
Wear particles promote reactive oxygen species-mediated inflammation via the nicotinamide adenine dinucleotide phosphate oxidase pathway in macrophages surrounding loosened implants.
Topics: Acetophenones; Adult; Aged; Animals; Catalase; Cell Line; Enzyme Inhibitors; Female; Humans; Inflamm | 2015 |
Lung Epithelial TRPA1 Transduces the Extracellular ROS into Transcriptional Regulation of Lung Inflammation Induced by Cigarette Smoke: The Role of Influxed Ca²⁺.
Topics: Acetanilides; Acetophenones; Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Calcium; Calcium Cha | 2015 |
Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson's Disease.
Topics: Acetophenones; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cel | 2016 |
Involvement of NADPH oxidases in alkali burn-induced corneal injury.
Topics: Acetophenones; Alkalies; Animals; Burns, Chemical; Corneal Injuries; Corneal Neovascularization; Enz | 2016 |
Apocynin Suppresses Lipopolysaccharide-Induced Inflammatory Responses Through the Inhibition of MAP Kinase Signaling Pathway in RAW264.7 Cells.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Cell Line; Cyclooxygenase 2; Dose-Response Relatio | 2016 |
Apocynin inhibits Toll-like receptor-4-mediated activation of NF-κB by suppressing the Akt and mTOR pathways.
Topics: Acetophenones; Anti-Inflammatory Agents; Antioxidants; Cells, Cultured; Cytokines; Dose-Response Rel | 2016 |
Association of serum HMGB2 level with MACE at 1 mo of myocardial infarction: Aggravation of myocardial ischemic injury in rats by HMGB2 via ROS.
Topics: Acetophenones; Aged; Animals; Apoptosis; Cell Line; Female; Glycation End Products, Advanced; Heart; | 2017 |
Combined NADPH and the NOX inhibitor apocynin provides greater anti-inflammatory and neuroprotective effects in a mouse model of stroke.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Brain Ischemia; Cyclooxygenase 2; Disease Models, | 2017 |
Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.
Topics: Acetophenones; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Astrocytes; Blood Pressu | 2008 |
NADPH oxidase contributes to renal damage and dysfunction in Dahl salt-sensitive hypertension.
Topics: Acetophenones; Allopurinol; Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Gene | 2008 |
Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion.
Topics: Acetophenones; Animals; Antioxidants; Brain Chemistry; Brain Infarction; Brain Ischemia; Inflammatio | 2009 |
In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012.
Topics: Acetophenones; Animals; Cyclic N-Oxides; Diagnostic Imaging; Inflammation; Luminescent Agents; Lumin | 2009 |
Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism.
Topics: Acetophenones; Aging; Androstadienes; Animals; Antioxidants; Aorta; Apoptosis; Diabetes Mellitus, Ty | 2010 |
Heme oxygenase 1 is differentially involved in blood flow-dependent arterial remodeling: role of inflammation, oxidative stress, and nitric oxide.
Topics: Acetophenones; Animals; Endothelium, Vascular; Heme Oxygenase-1; Hemodynamics; Inflammation; Macroph | 2011 |
Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms.
Topics: Acetophenones; Antibodies; Antioxidants; Blotting, Western; Cell Nucleus; Cells, Cultured; Cyclooxyg | 2004 |
Oral administration of the NADPH-oxidase inhibitor apocynin partially restores diminished cartilage proteoglycan synthesis and reduces inflammation in mice.
Topics: Acetophenones; Administration, Oral; Animals; Arthritis; Blood Cells; Cartilage, Articular; Dinopros | 2006 |
Endotoxin induces toll-like receptor 4 expression in vascular smooth muscle cells via NADPH oxidase activation and mitogen-activated protein kinase signaling pathways.
Topics: Acetophenones; Acetylcysteine; Animals; Aorta; Atherosclerosis; Cells, Cultured; Endotoxins; Enzyme | 2006 |
Apocynin alleviated hepatic oxidative burden and reduced liver injury in hypercholesterolaemia.
Topics: Acetophenones; Animals; Antioxidants; Cholesterol; Hepatocytes; Hypercholesterolemia; Inflammation; | 2007 |
Proliferation of airway epithelium after ozone exposure: effect of apocynin and dexamethasone.
Topics: Acetophenones; Administration, Oral; Air Pollutants; Animals; Anti-Inflammatory Agents; Anti-Inflamm | 1998 |