Page last updated: 2024-10-22

acetovanillone and Infarction, Middle Cerebral Artery

acetovanillone has been researched along with Infarction, Middle Cerebral Artery in 9 studies

apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.

Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.

Research Excerpts

ExcerptRelevanceReference
"This study utilized middle cerebral artery occlusion (MCAO) with tissue plasminogen activator (tPA) to assess inhibition of the NOX2 isoform of NADPH oxidase on brain injury and functional recovery in aged rats."1.35NOX2 inhibition with apocynin worsens stroke outcome in aged rats. ( Huber, JD; Kelly, KA; Li, X; Rosen, CL; Tan, Z; VanGilder, RL, 2009)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's5 (55.56)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Wang, Y1
Shen, Y1
Yu, X1
Gu, J1
Zhang, X1
Zhou, B1
Sun, Y1
Xu, C1
Qian, S1
Cananzi, SG1
Mayhan, WG2
Tang, X1
Zhong, W1
Tu, Q1
Ding, B1
Liu, W1
Sood, R1
Chen, Q1
Sakoglu, U1
Hendren, J1
Cetin, O1
Miyake, M1
Liu, KJ1
Jackman, KA1
Miller, AA1
De Silva, TM1
Crack, PJ1
Drummond, GR1
Sobey, CG1
Kelly, KA1
Li, X1
Tan, Z1
VanGilder, RL1
Rosen, CL1
Huber, JD1
Zhao, H1
Arrick, DM1
Xiong, W1
Sun, H1
Genovese, T1
Mazzon, E1
Paterniti, I1
Esposito, E1
Bramanti, P1
Cuzzocrea, S1
Connell, BJ1
Saleh, MC1
Khan, BV1
Rajagopal, D1
Saleh, TM1

Other Studies

9 other studies available for acetovanillone and Infarction, Middle Cerebral Artery

ArticleYear
Role of NADPH Oxidase-Induced Hypoxia-Induced Factor-1
    Neural plasticity, 2021, Volume: 2021

    Topics: Acetophenones; Animals; Blood-Brain Barrier; Disease Models, Animal; Enzyme Inhibitors; Hypoxia-Indu

2021
In Utero Exposure to Alcohol Impairs Reactivity of Cerebral Arterioles and Increases Susceptibility of the Brain to Damage Following Ischemia/Reperfusion in Adulthood.
    Alcoholism, clinical and experimental research, 2019, Volume: 43, Issue:4

    Topics: Acetophenones; Adenosine Diphosphate; Animals; Arterioles; Brain; Enzyme Inhibitors; Ethanol; Excita

2019
NADPH oxidase mediates the expression of MMP-9 in cerebral tissue after ischemia-reperfusion damage.
    Neurological research, 2014, Volume: 36, Issue:2

    Topics: Acetophenones; Animals; Blotting, Western; Brain; Brain Ischemia; Enzyme Inhibitors; Infarction, Mid

2014
Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke.
    Journal of neurochemistry, 2008, Volume: 107, Issue:5

    Topics: Acetophenones; Analysis of Variance; Animals; Blood-Brain Barrier; Brain Edema; Cerebral Cortex; Cla

2008
Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice.
    British journal of pharmacology, 2009, Volume: 156, Issue:4

    Topics: Acetophenones; Animals; Brain; Drug Administration Schedule; Infarction, Middle Cerebral Artery; Isc

2009
NOX2 inhibition with apocynin worsens stroke outcome in aged rats.
    Brain research, 2009, Oct-06, Volume: 1292

    Topics: Acetophenones; Aging; Animals; Antioxidants; Blood-Brain Barrier; Brain; Capillary Permeability; Ede

2009
Alcohol-induced exacerbation of ischemic brain injury: role of NAD(P)H oxidase.
    Alcoholism, clinical and experimental research, 2010, Volume: 34, Issue:11

    Topics: Acetophenones; Animals; Blotting, Western; Brain Ischemia; Central Nervous System Depressants; Ethan

2010
Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats.
    Brain research, 2011, Feb-04, Volume: 1372

    Topics: Acetophenones; Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Cytochromes c; Disease Models,

2011
UPEI-100, a conjugate of lipoic acid and apocynin, mediates neuroprotection in a rat model of ischemia/reperfusion.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2012, Volume: 302, Issue:7

    Topics: Acetophenones; Animals; Biomarkers; Disease Models, Animal; Glutathione Disulfide; Infarction, Middl

2012