acetovanillone has been researched along with Idiopathic Parkinson Disease in 7 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral administration of Mito-apocynin (10 mg/kg, thrice a week) showed excellent central nervous system bioavailability and significantly improved locomotor activity and coordination in MitoPark mice." | 1.46 | Mito-Apocynin Prevents Mitochondrial Dysfunction, Microglial Activation, Oxidative Damage, and Progressive Neurodegeneration in MitoPark Transgenic Mice. ( Anantharam, V; Ay, M; Bennett, B; Brenza, T; Charli, A; Ghaisas, S; Ghosh, A; Jin, H; Kalyanaraman, B; Kanthasamy, A; Kanthasamy, AG; Kim, D; Langley, M; Luo, J; Narasimhan, B; Sarkar, S; Schlichtmann, B; Zielonka, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Nascimento, ALF | 1 |
| Medeiros, POS | 1 |
| Pedrão, LFAT | 1 |
| Queiroz, VC | 1 |
| Oliveira, LM | 1 |
| Novaes, LS | 1 |
| Caetano, AL | 1 |
| Munhoz, CD | 1 |
| Takakura, AC | 1 |
| Falquetto, B | 1 |
| Langley, M | 1 |
| Ghosh, A | 1 |
| Charli, A | 1 |
| Sarkar, S | 1 |
| Ay, M | 1 |
| Luo, J | 1 |
| Zielonka, J | 2 |
| Brenza, T | 1 |
| Bennett, B | 1 |
| Jin, H | 1 |
| Ghaisas, S | 1 |
| Schlichtmann, B | 1 |
| Kim, D | 1 |
| Anantharam, V | 1 |
| Kanthasamy, A | 1 |
| Narasimhan, B | 1 |
| Kalyanaraman, B | 2 |
| Kanthasamy, AG | 2 |
| Hou, L | 2 |
| Sun, F | 2 |
| Huang, R | 1 |
| Sun, W | 1 |
| Zhang, D | 1 |
| Wang, Q | 2 |
| Dranka, BP | 1 |
| Gifford, A | 1 |
| McAllister, D | 1 |
| Joseph, J | 1 |
| O'Hara, CL | 1 |
| Stucky, CL | 1 |
| Sharma, N | 1 |
| Nehru, B | 1 |
| Zhang, C | 1 |
| Wang, K | 1 |
| Liu, X | 1 |
| Wang, H | 1 |
| Che, Y | 1 |
| Zhou, X | 1 |
| Zhao, X | 1 |
| Gao, HM | 1 |
| Liu, B | 1 |
| Hong, JS | 1 |
7 other studies available for acetovanillone and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Oxidative Stress Inhibition Via Apocynin Prevents Medullary Respiratory Neurodegeneration and Respiratory Pattern Dysfunction in a 6-Hydroxydopamine Animal Model of Parkinson's Disease.
Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Drinking Water; NADPH Oxidases; Oxidative Str | 2022 |
Mito-Apocynin Prevents Mitochondrial Dysfunction, Microglial Activation, Oxidative Damage, and Progressive Neurodegeneration in MitoPark Transgenic Mice.
Topics: Acetophenones; Administration, Oral; Animals; Antioxidants; Cells, Cultured; Disease Models, Animal; | 2017 |
Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model.
Topics: Acetophenones; Animals; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Dopaminergic Neur | 2019 |
A novel mitochondrially-targeted apocynin derivative prevents hyposmia and loss of motor function in the leucine-rich repeat kinase 2 (LRRK2(R1441G)) transgenic mouse model of Parkinson's disease.
Topics: Acetophenones; Animals; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice, Transgenic; Mit | 2014 |
Apocyanin, a Microglial NADPH Oxidase Inhibitor Prevents Dopaminergic Neuronal Degeneration in Lipopolysaccharide-Induced Parkinson's Disease Model.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetophenones; Animals; Cytokines; Disease Models, Animal; Dopaminer | 2016 |
Paraquat and maneb co-exposure induces noradrenergic locus coeruleus neurodegeneration through NADPH oxidase-mediated microglial activation.
Topics: Acetophenones; Adrenergic Neurons; Animals; Disease Models, Animal; Enzyme Inhibitors; Locus Coerule | 2017 |
Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons.
Topics: Acetophenones; Animals; Cells, Cultured; Coculture Techniques; Dopamine; Drug Resistance; Enzyme Inh | 2003 |