acetovanillone has been researched along with Diabetic Nephropathies in 9 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In rats with diabetic nephropathy, apocynin (1) reduced renal injury and improved renal function; (2) downregulated the expression of NLRP3 in renal cortex; (3) downregulated the expression of XIAP in renal cortex; and (4) attenuated renal fibrosis." | 1.48 | Apocynin inhibited NLRP3/XIAP signalling to alleviate renal fibrotic injury in rat diabetic nephropathy. ( Du, P; Hou, Y; Jiang, W; Li, X; Sun, W; Sun, X; Wang, L; Wang, Z; Xiang, Y; Xin, R; Yuan, W; Zhang, H, 2018) |
| "Diabetic nephropathy is the most serious complication in diabetes mellitus." | 1.35 | Effects of NADPH oxidase inhibitor on diabetic nephropathy in OLETF rats: the role of reducing oxidative stress in its protective property. ( Chung, CH; Koh, JH; Koh, SB; Lee, EY; Lee, MY; Nam, SM; Park, JH; Shin, JY; Shin, YG, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xin, R | 1 |
| Sun, X | 1 |
| Wang, Z | 1 |
| Yuan, W | 1 |
| Jiang, W | 1 |
| Wang, L | 1 |
| Xiang, Y | 1 |
| Zhang, H | 1 |
| Li, X | 1 |
| Hou, Y | 1 |
| Sun, W | 1 |
| Du, P | 1 |
| Nam, SM | 1 |
| Lee, MY | 1 |
| Koh, JH | 1 |
| Park, JH | 1 |
| Shin, JY | 1 |
| Shin, YG | 1 |
| Koh, SB | 1 |
| Lee, EY | 1 |
| Chung, CH | 1 |
| Thallas-Bonke, V | 2 |
| Coughlan, MT | 2 |
| Bach, LA | 2 |
| Cooper, ME | 2 |
| Forbes, JM | 2 |
| Edlund, J | 1 |
| Fasching, A | 1 |
| Liss, P | 1 |
| Hansell, P | 1 |
| Palm, F | 1 |
| Zhang, Y | 1 |
| Peng, F | 1 |
| Gao, B | 1 |
| Ingram, AJ | 1 |
| Krepinsky, JC | 1 |
| Fujita, H | 1 |
| Fujishima, H | 1 |
| Morii, T | 1 |
| Sakamoto, T | 1 |
| Komatsu, K | 1 |
| Hosoba, M | 1 |
| Narita, T | 1 |
| Takahashi, K | 1 |
| Takahashi, T | 1 |
| Yamada, Y | 1 |
| Ahmad, A | 1 |
| Mondello, S | 1 |
| Di Paola, R | 1 |
| Mazzon, E | 1 |
| Esposito, E | 1 |
| Catania, MA | 1 |
| Italiano, D | 1 |
| Mondello, P | 1 |
| Aloisi, C | 1 |
| Cuzzocrea, S | 1 |
| Asaba, K | 1 |
| Tojo, A | 1 |
| Onozato, ML | 1 |
| Goto, A | 1 |
| Quinn, MT | 1 |
| Fujita, T | 1 |
| Wilcox, CS | 1 |
| Thorpe, SR | 1 |
| Fukami, K | 1 |
| Yap, FY | 1 |
| Sourris, KC | 1 |
| Penfold, SA | 1 |
9 other studies available for acetovanillone and Diabetic Nephropathies
| Article | Year |
|---|---|
Apocynin inhibited NLRP3/XIAP signalling to alleviate renal fibrotic injury in rat diabetic nephropathy.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Antioxidants; Cytoprotection; Diabetes Mellitus, E | 2018 |
Effects of NADPH oxidase inhibitor on diabetic nephropathy in OLETF rats: the role of reducing oxidative stress in its protective property.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetophenones; Animals; Cytoprotection; Deoxyguanosine; Diabetes Mellit | 2009 |
Preservation of kidney function with combined inhibition of NADPH oxidase and angiotensin-converting enzyme in diabetic nephropathy.
Topics: Acetophenones; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Ex | 2010 |
The roles of NADPH-oxidase and nNOS for the increased oxidative stress and the oxygen consumption in the diabetic kidney.
Topics: Acetophenones; Animals; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney; | 2010 |
High glucose-induced RhoA activation requires caveolae and PKCĪ²1-mediated ROS generation.
Topics: Acetophenones; Acetylcysteine; Animals; Carbazoles; Caveolae; Cyclodextrins; Diabetic Nephropathies; | 2012 |
Modulation of renal superoxide dismutase by telmisartan therapy in C57BL/6-Ins2(Akita) diabetic mice.
Topics: Acetophenones; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents | 2012 |
Protective effect of apocynin, a NADPH-oxidase inhibitor, against contrast-induced nephropathy in the diabetic rats: a comparison with n-acetylcysteine.
Topics: Acetophenones; Acetylcysteine; Acute-Phase Proteins; Animals; Apoptosis; Contrast Media; Cytosine; D | 2012 |
Effects of NADPH oxidase inhibitor in diabetic nephropathy.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; | 2005 |
Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; | 2008 |