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acetovanillone and Diabetic Nephropathies

acetovanillone has been researched along with Diabetic Nephropathies in 9 studies

apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.

Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.

Research Excerpts

ExcerptRelevanceReference
"In rats with diabetic nephropathy, apocynin (1) reduced renal injury and improved renal function; (2) downregulated the expression of NLRP3 in renal cortex; (3) downregulated the expression of XIAP in renal cortex; and (4) attenuated renal fibrosis."1.48Apocynin inhibited NLRP3/XIAP signalling to alleviate renal fibrotic injury in rat diabetic nephropathy. ( Du, P; Hou, Y; Jiang, W; Li, X; Sun, W; Sun, X; Wang, L; Wang, Z; Xiang, Y; Xin, R; Yuan, W; Zhang, H, 2018)
"Diabetic nephropathy is the most serious complication in diabetes mellitus."1.35Effects of NADPH oxidase inhibitor on diabetic nephropathy in OLETF rats: the role of reducing oxidative stress in its protective property. ( Chung, CH; Koh, JH; Koh, SB; Lee, EY; Lee, MY; Nam, SM; Park, JH; Shin, JY; Shin, YG, 2009)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xin, R1
Sun, X1
Wang, Z1
Yuan, W1
Jiang, W1
Wang, L1
Xiang, Y1
Zhang, H1
Li, X1
Hou, Y1
Sun, W1
Du, P1
Nam, SM1
Lee, MY1
Koh, JH1
Park, JH1
Shin, JY1
Shin, YG1
Koh, SB1
Lee, EY1
Chung, CH1
Thallas-Bonke, V2
Coughlan, MT2
Bach, LA2
Cooper, ME2
Forbes, JM2
Edlund, J1
Fasching, A1
Liss, P1
Hansell, P1
Palm, F1
Zhang, Y1
Peng, F1
Gao, B1
Ingram, AJ1
Krepinsky, JC1
Fujita, H1
Fujishima, H1
Morii, T1
Sakamoto, T1
Komatsu, K1
Hosoba, M1
Narita, T1
Takahashi, K1
Takahashi, T1
Yamada, Y1
Ahmad, A1
Mondello, S1
Di Paola, R1
Mazzon, E1
Esposito, E1
Catania, MA1
Italiano, D1
Mondello, P1
Aloisi, C1
Cuzzocrea, S1
Asaba, K1
Tojo, A1
Onozato, ML1
Goto, A1
Quinn, MT1
Fujita, T1
Wilcox, CS1
Thorpe, SR1
Fukami, K1
Yap, FY1
Sourris, KC1
Penfold, SA1

Other Studies

9 other studies available for acetovanillone and Diabetic Nephropathies

ArticleYear
Apocynin inhibited NLRP3/XIAP signalling to alleviate renal fibrotic injury in rat diabetic nephropathy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 106

    Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Antioxidants; Cytoprotection; Diabetes Mellitus, E

2018
Effects of NADPH oxidase inhibitor on diabetic nephropathy in OLETF rats: the role of reducing oxidative stress in its protective property.
    Diabetes research and clinical practice, 2009, Volume: 83, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetophenones; Animals; Cytoprotection; Deoxyguanosine; Diabetes Mellit

2009
Preservation of kidney function with combined inhibition of NADPH oxidase and angiotensin-converting enzyme in diabetic nephropathy.
    American journal of nephrology, 2010, Volume: 32, Issue:1

    Topics: Acetophenones; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Ex

2010
The roles of NADPH-oxidase and nNOS for the increased oxidative stress and the oxygen consumption in the diabetic kidney.
    Diabetes/metabolism research and reviews, 2010, Volume: 26, Issue:5

    Topics: Acetophenones; Animals; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney;

2010
High glucose-induced RhoA activation requires caveolae and PKCĪ²1-mediated ROS generation.
    American journal of physiology. Renal physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Acetophenones; Acetylcysteine; Animals; Carbazoles; Caveolae; Cyclodextrins; Diabetic Nephropathies;

2012
Modulation of renal superoxide dismutase by telmisartan therapy in C57BL/6-Ins2(Akita) diabetic mice.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:2

    Topics: Acetophenones; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents

2012
Protective effect of apocynin, a NADPH-oxidase inhibitor, against contrast-induced nephropathy in the diabetic rats: a comparison with n-acetylcysteine.
    European journal of pharmacology, 2012, Jan-15, Volume: 674, Issue:2-3

    Topics: Acetophenones; Acetylcysteine; Acute-Phase Proteins; Animals; Apoptosis; Contrast Media; Cytosine; D

2012
Effects of NADPH oxidase inhibitor in diabetic nephropathy.
    Kidney international, 2005, Volume: 67, Issue:5

    Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors;

2005
Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway.
    Diabetes, 2008, Volume: 57, Issue:2

    Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors;

2008