acetovanillone and Cardiomegaly
acetovanillone has been researched along with Cardiomegaly in 8 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
" As evident from the HW/BW ratio, HW/TL ratio, echocardiography, and histopathology, hypertrophic responses induced by isoproterenol (Iso; 5 mg/Kg body weight, subcutaneous) were blocked by Apo (10 mg/Kg body weight, intraperitoneal)." | 7.88 | Apocynin prevents isoproterenol-induced cardiac hypertrophy in rat. ( Goswami, SK; Prasad, A; Saleem, N, 2018) |
"The ability of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor simvastatin to reverse established cardiovascular and renal alterations and oxidative stress was assessed in angiotensin II (AngII) hypertension." | 7.74 | Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine. ( Delbosc, S; Jover, B; Mimran, A; Rugale, C, 2007) |
" As evident from the HW/BW ratio, HW/TL ratio, echocardiography, and histopathology, hypertrophic responses induced by isoproterenol (Iso; 5 mg/Kg body weight, subcutaneous) were blocked by Apo (10 mg/Kg body weight, intraperitoneal)." | 3.88 | Apocynin prevents isoproterenol-induced cardiac hypertrophy in rat. ( Goswami, SK; Prasad, A; Saleem, N, 2018) |
"67 Mb heterozygous deletion including the Eln gene, presented with a generalized arteriopathy, hypertension, and cardiac hypertrophy, associated with elevated angiotensin II (angII), oxidative stress parameters, and Ncf1 expression." | 3.78 | Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome. ( Bustelo, XR; Campuzano, V; Coustets, M; Francke, U; Menacho-Márquez, M; Nevado, J; Pérez-Jurado, LA; Sánchez-Rodríguez, C; Segura-Puimedon, M; Terrado, V, 2012) |
"The ability of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor simvastatin to reverse established cardiovascular and renal alterations and oxidative stress was assessed in angiotensin II (AngII) hypertension." | 3.74 | Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine. ( Delbosc, S; Jover, B; Mimran, A; Rugale, C, 2007) |
"Type 4 cardiorenal syndrome (CRS) refers to the cardiac injury induced by chronic kidney disease." | 1.42 | Apocynin Attenuates Cardiac Injury in Type 4 Cardiorenal Syndrome via Suppressing Cardiac Fibroblast Growth Factor-2 With Oxidative Stress Inhibition. ( Chen, J; Huang, F; Huang, H; Liu, X; Liu, Y; Tang, W; Wang, JF; Zhang, K, 2015) |
"After abdominal aorta banding to induce cardiac hypertrophy, rats were treated for 8 weeks with apocynin (Apo) or captopril (Cap)." | 1.36 | Apocynin attenuates pressure overload-induced cardiac hypertrophy in rats by reducing levels of reactive oxygen species. ( An, W; Lin, Y; Liu, J; Yang, Y; Zang, W; Zhou, J, 2010) |
Research
Studies (8)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (25.00) | 29.6817 |
2010's | 6 (75.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Saleem, N | 1 |
Prasad, A | 1 |
Goswami, SK | 1 |
Liu, Y | 2 |
Liu, X | 1 |
Chen, J | 1 |
Zhang, K | 1 |
Huang, F | 1 |
Wang, JF | 1 |
Tang, W | 1 |
Huang, H | 1 |
Buday, A | 1 |
Orsy, P | 1 |
Godó, M | 1 |
Mózes, M | 1 |
Kökény, G | 1 |
Lacza, Z | 1 |
Koller, A | 1 |
Ungvári, Z | 1 |
Gross, ML | 1 |
Benyó, Z | 1 |
Hamar, P | 1 |
Liu, J | 1 |
Zhou, J | 1 |
An, W | 1 |
Lin, Y | 1 |
Yang, Y | 1 |
Zang, W | 1 |
Campuzano, V | 1 |
Segura-Puimedon, M | 1 |
Terrado, V | 1 |
Sánchez-Rodríguez, C | 1 |
Coustets, M | 1 |
Menacho-Márquez, M | 1 |
Nevado, J | 1 |
Bustelo, XR | 1 |
Francke, U | 1 |
Pérez-Jurado, LA | 1 |
Li, YQ | 1 |
Li, XB | 1 |
Guo, SJ | 1 |
Chu, SL | 1 |
Gao, PJ | 1 |
Zhu, DL | 1 |
Niu, WQ | 1 |
Jia, N | 1 |
Kase, H | 1 |
Hashikabe, Y | 1 |
Uchida, K | 1 |
Nakanishi, N | 1 |
Hattori, Y | 1 |
Rugale, C | 1 |
Delbosc, S | 1 |
Mimran, A | 1 |
Jover, B | 1 |
Other Studies
8 other studies available for acetovanillone and Cardiomegaly
Article | Year |
---|---|
Apocynin prevents isoproterenol-induced cardiac hypertrophy in rat.
Topics: Acetophenones; Adrenergic beta-Agonists; Animals; Biomarkers; Body Weight; Cardiomegaly; Echocardiog | 2018 |
Apocynin Attenuates Cardiac Injury in Type 4 Cardiorenal Syndrome via Suppressing Cardiac Fibroblast Growth Factor-2 With Oxidative Stress Inhibition.
Topics: Acetophenones; Aged; Aged, 80 and over; Animals; Antioxidants; Cardio-Renal Syndrome; Cardiomegaly; | 2015 |
Elevated systemic TGF-beta impairs aortic vasomotor function through activation of NADPH oxidase-driven superoxide production and leads to hypertension, myocardial remodeling, and increased plaque formation in apoE(-/-) mice.
Topics: Acetophenones; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Body Weight; Card | 2010 |
Apocynin attenuates pressure overload-induced cardiac hypertrophy in rats by reducing levels of reactive oxygen species.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Atrial Natriuretic Factor; Base Sequence; Capt | 2010 |
Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.
Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Blood Pre | 2012 |
Apocynin attenuates oxidative stress and cardiac fibrosis in angiotensin II-induced cardiac diastolic dysfunction in mice.
Topics: Acetophenones; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Cardiomegaly; Cardiotonic | 2013 |
Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Biopterins; Cardiomegaly; Dis | 2005 |
Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine.
Topics: Acetophenones; Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Cardiome | 2007 |