acetovanillone has been researched along with Cardiac Hypertrophy in 8 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| " As evident from the HW/BW ratio, HW/TL ratio, echocardiography, and histopathology, hypertrophic responses induced by isoproterenol (Iso; 5 mg/Kg body weight, subcutaneous) were blocked by Apo (10 mg/Kg body weight, intraperitoneal)." | 7.88 | Apocynin prevents isoproterenol-induced cardiac hypertrophy in rat. ( Goswami, SK; Prasad, A; Saleem, N, 2018) |
| "The ability of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor simvastatin to reverse established cardiovascular and renal alterations and oxidative stress was assessed in angiotensin II (AngII) hypertension." | 7.74 | Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine. ( Delbosc, S; Jover, B; Mimran, A; Rugale, C, 2007) |
| " As evident from the HW/BW ratio, HW/TL ratio, echocardiography, and histopathology, hypertrophic responses induced by isoproterenol (Iso; 5 mg/Kg body weight, subcutaneous) were blocked by Apo (10 mg/Kg body weight, intraperitoneal)." | 3.88 | Apocynin prevents isoproterenol-induced cardiac hypertrophy in rat. ( Goswami, SK; Prasad, A; Saleem, N, 2018) |
| "67 Mb heterozygous deletion including the Eln gene, presented with a generalized arteriopathy, hypertension, and cardiac hypertrophy, associated with elevated angiotensin II (angII), oxidative stress parameters, and Ncf1 expression." | 3.78 | Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome. ( Bustelo, XR; Campuzano, V; Coustets, M; Francke, U; Menacho-Márquez, M; Nevado, J; Pérez-Jurado, LA; Sánchez-Rodríguez, C; Segura-Puimedon, M; Terrado, V, 2012) |
| "The ability of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor simvastatin to reverse established cardiovascular and renal alterations and oxidative stress was assessed in angiotensin II (AngII) hypertension." | 3.74 | Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine. ( Delbosc, S; Jover, B; Mimran, A; Rugale, C, 2007) |
| "Type 4 cardiorenal syndrome (CRS) refers to the cardiac injury induced by chronic kidney disease." | 1.42 | Apocynin Attenuates Cardiac Injury in Type 4 Cardiorenal Syndrome via Suppressing Cardiac Fibroblast Growth Factor-2 With Oxidative Stress Inhibition. ( Chen, J; Huang, F; Huang, H; Liu, X; Liu, Y; Tang, W; Wang, JF; Zhang, K, 2015) |
| "After abdominal aorta banding to induce cardiac hypertrophy, rats were treated for 8 weeks with apocynin (Apo) or captopril (Cap)." | 1.36 | Apocynin attenuates pressure overload-induced cardiac hypertrophy in rats by reducing levels of reactive oxygen species. ( An, W; Lin, Y; Liu, J; Yang, Y; Zang, W; Zhou, J, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saleem, N | 1 |
| Prasad, A | 1 |
| Goswami, SK | 1 |
| Liu, Y | 2 |
| Liu, X | 1 |
| Chen, J | 1 |
| Zhang, K | 1 |
| Huang, F | 1 |
| Wang, JF | 1 |
| Tang, W | 1 |
| Huang, H | 1 |
| Buday, A | 1 |
| Orsy, P | 1 |
| Godó, M | 1 |
| Mózes, M | 1 |
| Kökény, G | 1 |
| Lacza, Z | 1 |
| Koller, A | 1 |
| Ungvári, Z | 1 |
| Gross, ML | 1 |
| Benyó, Z | 1 |
| Hamar, P | 1 |
| Liu, J | 1 |
| Zhou, J | 1 |
| An, W | 1 |
| Lin, Y | 1 |
| Yang, Y | 1 |
| Zang, W | 1 |
| Campuzano, V | 1 |
| Segura-Puimedon, M | 1 |
| Terrado, V | 1 |
| Sánchez-Rodríguez, C | 1 |
| Coustets, M | 1 |
| Menacho-Márquez, M | 1 |
| Nevado, J | 1 |
| Bustelo, XR | 1 |
| Francke, U | 1 |
| Pérez-Jurado, LA | 1 |
| Li, YQ | 1 |
| Li, XB | 1 |
| Guo, SJ | 1 |
| Chu, SL | 1 |
| Gao, PJ | 1 |
| Zhu, DL | 1 |
| Niu, WQ | 1 |
| Jia, N | 1 |
| Kase, H | 1 |
| Hashikabe, Y | 1 |
| Uchida, K | 1 |
| Nakanishi, N | 1 |
| Hattori, Y | 1 |
| Rugale, C | 1 |
| Delbosc, S | 1 |
| Mimran, A | 1 |
| Jover, B | 1 |
8 other studies available for acetovanillone and Cardiac Hypertrophy
| Article | Year |
|---|---|
Apocynin prevents isoproterenol-induced cardiac hypertrophy in rat.
Topics: Acetophenones; Adrenergic beta-Agonists; Animals; Biomarkers; Body Weight; Cardiomegaly; Echocardiog | 2018 |
Apocynin Attenuates Cardiac Injury in Type 4 Cardiorenal Syndrome via Suppressing Cardiac Fibroblast Growth Factor-2 With Oxidative Stress Inhibition.
Topics: Acetophenones; Aged; Aged, 80 and over; Animals; Antioxidants; Cardio-Renal Syndrome; Cardiomegaly; | 2015 |
Elevated systemic TGF-beta impairs aortic vasomotor function through activation of NADPH oxidase-driven superoxide production and leads to hypertension, myocardial remodeling, and increased plaque formation in apoE(-/-) mice.
Topics: Acetophenones; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Body Weight; Card | 2010 |
Apocynin attenuates pressure overload-induced cardiac hypertrophy in rats by reducing levels of reactive oxygen species.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Atrial Natriuretic Factor; Base Sequence; Capt | 2010 |
Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.
Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Blood Pre | 2012 |
Apocynin attenuates oxidative stress and cardiac fibrosis in angiotensin II-induced cardiac diastolic dysfunction in mice.
Topics: Acetophenones; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Cardiomegaly; Cardiotonic | 2013 |
Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Biopterins; Cardiomegaly; Dis | 2005 |
Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine.
Topics: Acetophenones; Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Cardiome | 2007 |