acetovanillone has been researched along with Bronchial Hyperreactivity in 5 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| " At 36 h before and 16 h after O(3) exposure, methacholine inhalation challenge tests (Mch) were performed, and PC(20) and maximal % fall from baseline (MFEV(1)) were calculated from dose-response curves." | 6.70 | Effect of apocynin on ozone-induced airway hyperresponsiveness to methacholine in asthmatics. ( Hiltermann, JT; Peters, EA; Stolk, J, 2001) |
| " At 36 h before and 16 h after O(3) exposure, methacholine inhalation challenge tests (Mch) were performed, and PC(20) and maximal % fall from baseline (MFEV(1)) were calculated from dose-response curves." | 2.70 | Effect of apocynin on ozone-induced airway hyperresponsiveness to methacholine in asthmatics. ( Hiltermann, JT; Peters, EA; Stolk, J, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsukagoshi, H | 2 |
| Robbins, RA | 1 |
| Barnes, PJ | 1 |
| Chung, KF | 1 |
| Nishikawa, M | 1 |
| Kudo, M | 1 |
| Kakemizu, N | 1 |
| Ikeda, H | 1 |
| Okubo, T | 1 |
| Iwamae, S | 1 |
| Hisada, T | 1 |
| Uno, D | 1 |
| Mori, M | 1 |
| Muijsers, RB | 1 |
| van Ark, I | 1 |
| Folkerts, G | 1 |
| Koster, AS | 1 |
| van Oosterhout, AJ | 1 |
| Postma, DS | 1 |
| Nijkamp, FP | 1 |
| Peters, EA | 1 |
| Hiltermann, JT | 1 |
| Stolk, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inhaled Apocynin Decreases Reactive Oxygen Species Concentrations in Exhaled Breath Condensate in Mild Asthmatics[NCT00992667] | Phase 1 | 10 participants (Actual) | Interventional | 2008-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for acetovanillone and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Effect of apocynin on ozone-induced airway hyperresponsiveness to methacholine in asthmatics.
Topics: Acetophenones; Administration, Inhalation; Adult; Aerosols; Antioxidants; Asthma; Bronchial Hyperrea | 2001 |
4 other studies available for acetovanillone and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Role of nitric oxide and superoxide anions in interleukin-1 beta-induced airway hyperresponsiveness to bradykinin.
Topics: Acetophenones; Animals; Arginine; Bradykinin; Bronchial Hyperreactivity; Bronchoalveolar Lavage Flui | 1994 |
Role of superoxide anions in airway hyperresponsiveness induced by cigarette smoke in conscious guinea pigs.
Topics: Acetophenones; Administration, Inhalation; Aerosols; Animals; Bronchial Hyperreactivity; Bronchial P | 1996 |
A possible involvement of oxidative lung injury in endotoxin-induced bronchial hyperresponsiveness to substance P in guinea pigs.
Topics: Acetophenones; Aminophylline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Bronchial H | 1998 |
Apocynin and 1400 W prevents airway hyperresponsiveness during allergic reactions in mice.
Topics: Acetophenones; Amidines; Animals; Antioxidants; Benzylamines; Bronchial Hyperreactivity; Bronchoalve | 2001 |