acetovanillone has been researched along with Blood Pressure, High in 86 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moderate (approximately 2-fold) increases in plasma unconjugated bilirubin levels are able to attenuate the development of angiotensin II (Ang II)-dependent hypertension." | 7.79 | Antihypertensive actions of moderate hyperbilirubinemia: role of superoxide inhibition. ( Gousset, MU; Pruett, BE; Stec, DE; Storm, MV, 2013) |
| " Cadmium toxicity is reported to causes oxidative damage, resulting in vascular dysfunction, reduced bioavailability of nitric oxide (NO) and hypertension." | 7.79 | Apocynin ameliorates cadmium-induced hypertension through elevation of endothelium nitric oxide synthase. ( Baker, A; Brown, PD; Douglas, D; McCalla, G; Nwokocha, CR; Nwokocha, M, 2013) |
| " Despite comparable hypotensive effects between valsartan and hydralazine in salt-loaded SHRSP, valsartan reduced cerebral NADPH oxidase activity and ROS more than hydralazine being accompanied by more prevention of stroke by valsartan than hydralazine." | 7.74 | Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation. ( Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tamamaki, N; Tokutomi, Y; Yamamoto, E, 2008) |
| "The ability of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor simvastatin to reverse established cardiovascular and renal alterations and oxidative stress was assessed in angiotensin II (AngII) hypertension." | 7.74 | Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine. ( Delbosc, S; Jover, B; Mimran, A; Rugale, C, 2007) |
| "Apocynin but not allopurinol prevented and reversed ACTH-induced hypertension in the rat." | 7.73 | Apocynin but not allopurinol prevents and reverses adrenocorticotropic hormone-induced hypertension in the rat. ( Andrews, MC; Chan, MM; Croft, KD; McKenzie, KU; Mori, TA; Schyvens, CG; Whitworth, JA; Zhang, Y, 2005) |
| "In male SD rats, apocynin but not l-arginine prevented and reversed Dex-hypertension, suggesting that NAD(P)H oxidase-mediated superoxide production but not endothelial nitric oxide synthase uncoupling is important in Dex-hypertension." | 7.73 | Apocynin but not L-arginine prevents and reverses dexamethasone-induced hypertension in the rat. ( Hu, L; Lim, PS; McKenzie, KU; Miao, Y; Schyvens, CG; Tan, C; Whitworth, JA; Zhang, Y, 2006) |
| " Unfortunately, the treatment with CSA is often limited by severe adverse effects such as hypertension and nephrotoxicity." | 5.42 | The Protective Effect of Apocynin on Cyclosporine A-Induced Hypertension and Nephrotoxicity in Rats. ( Capasso, G; Ciarcia, R; Damiano, S; Florio, A; Florio, S; Garofano, T; Giordano, A; Mirabella, N; Pagnini, U; Polito, MS; Spagnuolo, M; Squillacioti, C; Zacchia, E, 2015) |
| " Preincubation with sepiapterin (10 μmol/l for 30 min) failed to improve NO(·) bioavailability in hypertensive aortas while it augmented NO(·) production from control vessels, implicating a hypertension-associated deficiency in sepiapterin reductase (SPR), the rate-limiting enzyme for sepiapterin conversion to H(4)B." | 5.38 | Endothelium-specific sepiapterin reductase deficiency in DOCA-salt hypertension. ( Blair, J; Cai, H; Harrison, DG; Laude, KM; McCann, LA; Oak, JH; Wang, T; Youn, JY, 2012) |
| "Enalapril prevented the increase in heart weight index (HWI), carotid cross-sectional area (CSA) and albuminuria induced by Ang II." | 5.33 | Prevention and reversal by enalapril of target organ damage in angiotensin II hypertension. ( Cordaillat, M; Jover, B; Mimran, A; Rugale, C, 2005) |
| "Increased bioavailability of reactive oxygen species (ROS) has been implicated in the pathogenesis of mineralocorticoid hypertension." | 5.32 | NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats. ( Park, JB; Park, MY; Park, YM; Suh, YL, 2004) |
| "These results demonstrate that the formation of ROS in the commNTS is important to maintain sympathoexcitation and hypertension in 2K1C rats and suggest that NADPH oxidase in the commNTS could be a potential target for therapeutics in renovascular hypertension." | 4.31 | Acute inhibition of nicotinamide adenine dinucleotide phosphate oxidase in the commissural nucleus of the solitary tract reduces arterial pressure and renal sympathetic nerve activity in renovascular hypertension. ( Colombari, DSA; Colombari, E; Ferreira-Neto, ML; Marques, SM; Melo, MR; Menani, JV; Pedrino, GR; Xavier, CH; Zoccal, DB, 2023) |
| "We investigated whether hypertension induced by maternal lipopolysaccharide (LPS) administration during gestation is linked to peripheral vascular and renal hemodynamic regulation, through angiotensin II → NADPH-oxidase signalling, and whether these changes are directly linked to intrauterine oxidative stress." | 3.88 | Oxidative stress induced by prenatal LPS leads to endothelial dysfunction and renal haemodynamic changes through angiotensin II/NADPH oxidase pathway: Prevention by early treatment with α-tocopherol. ( Aires, RS; Cabral, EV; de Queiroz, DB; Farias, JS; Lima-Filho, MM; Paixão, AD; Ribeiro, VS; Sant'Helena, BRM; Santos-Rocha, J; Vieira, LD; Xavier, FE, 2018) |
| "Moderate (approximately 2-fold) increases in plasma unconjugated bilirubin levels are able to attenuate the development of angiotensin II (Ang II)-dependent hypertension." | 3.79 | Antihypertensive actions of moderate hyperbilirubinemia: role of superoxide inhibition. ( Gousset, MU; Pruett, BE; Stec, DE; Storm, MV, 2013) |
| " Cadmium toxicity is reported to causes oxidative damage, resulting in vascular dysfunction, reduced bioavailability of nitric oxide (NO) and hypertension." | 3.79 | Apocynin ameliorates cadmium-induced hypertension through elevation of endothelium nitric oxide synthase. ( Baker, A; Brown, PD; Douglas, D; McCalla, G; Nwokocha, CR; Nwokocha, M, 2013) |
| "Apocynin, Mito-TEMPO, and Celecoxib treatments prevented Ang II-induced hypertension, the increased vasoconstrictor responses to phenylephrine, and the reduced acetylcholine relaxation." | 3.79 | Reciprocal relationship between reactive oxygen species and cyclooxygenase-2 and vascular dysfunction in hypertension. ( Aguado, A; Alonso, MJ; Alvarez, Y; Avendaño, MS; Briones, AM; Esteban, V; García-Redondo, AB; García-Redondo, L; Martínez-Revelles, S; Pérez-Girón, JV; Redondo, JM; Salaices, M, 2013) |
| "Both NADPH oxidase-derived reactive oxygen species (ROS) and asymmetric dimethylarginine (ADMA) are increased in hypertension." | 3.78 | Apocynin attenuates oxidative stress and hypertension in young spontaneously hypertensive rats independent of ADMA/NO pathway. ( Hsu, CN; Huang, LT; Lau, YT; Tain, YL, 2012) |
| "67 Mb heterozygous deletion including the Eln gene, presented with a generalized arteriopathy, hypertension, and cardiac hypertrophy, associated with elevated angiotensin II (angII), oxidative stress parameters, and Ncf1 expression." | 3.78 | Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome. ( Bustelo, XR; Campuzano, V; Coustets, M; Francke, U; Menacho-Márquez, M; Nevado, J; Pérez-Jurado, LA; Sánchez-Rodríguez, C; Segura-Puimedon, M; Terrado, V, 2012) |
| "The present findings suggest that antenatal nicotine exposure results in the programming of heightened oxidative stress and vascular hypertensive reactivity via a Nox2-dependent mechanism, leading to an increased risk of hypertension in adult offspring." | 3.77 | Antenatal nicotine induces heightened oxidative stress and vascular dysfunction in rat offspring. ( Huang, X; Xiao, D; Yang, S; Zhang, L, 2011) |
| " Despite comparable hypotensive effects between valsartan and hydralazine in salt-loaded SHRSP, valsartan reduced cerebral NADPH oxidase activity and ROS more than hydralazine being accompanied by more prevention of stroke by valsartan than hydralazine." | 3.74 | Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation. ( Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tamamaki, N; Tokutomi, Y; Yamamoto, E, 2008) |
| "The ability of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor simvastatin to reverse established cardiovascular and renal alterations and oxidative stress was assessed in angiotensin II (AngII) hypertension." | 3.74 | Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine. ( Delbosc, S; Jover, B; Mimran, A; Rugale, C, 2007) |
| "Apocynin but not allopurinol prevented and reversed ACTH-induced hypertension in the rat." | 3.73 | Apocynin but not allopurinol prevents and reverses adrenocorticotropic hormone-induced hypertension in the rat. ( Andrews, MC; Chan, MM; Croft, KD; McKenzie, KU; Mori, TA; Schyvens, CG; Whitworth, JA; Zhang, Y, 2005) |
| "Recent studies suggest that adipose tissue hormone, leptin, is involved in the pathogenesis of arterial hypertension." | 3.73 | Antioxidant treatment normalizes nitric oxide production, renal sodium handling and blood pressure in experimental hyperleptinemia. ( Beltowski, J; Borkowska, E; Jamroz-Wiśniewska, A; Marciniak, A; Wójcicka, G, 2005) |
| "Fibroblasts are involved in the remodeling of the heart and of the vasculature associated to arterial hypertension, and an abnormal extracellular signal-regulated kinase 1/2 (ERK1/2) activation by angiotensin II (Ang II) plays a pivotal role in this process." | 3.73 | Angiotensin II-induced over-activation of p47phox in fibroblasts from hypertensives: which role in the enhanced ERK1/2 responsiveness to angiotensin II? ( Ceolotto, G; Ciccariello, L; Franco, L; Lenzini, L; Mazzoni, M; Papparella, I; Sartori, M; Semplicini, A, 2005) |
| "In male SD rats, apocynin but not l-arginine prevented and reversed Dex-hypertension, suggesting that NAD(P)H oxidase-mediated superoxide production but not endothelial nitric oxide synthase uncoupling is important in Dex-hypertension." | 3.73 | Apocynin but not L-arginine prevents and reverses dexamethasone-induced hypertension in the rat. ( Hu, L; Lim, PS; McKenzie, KU; Miao, Y; Schyvens, CG; Tan, C; Whitworth, JA; Zhang, Y, 2006) |
| "To examine the hypothesis that NAD(P)H oxidase (Nox)-derived superoxide generation is involved in the development of angiotensin II (ANG II)-induced hypertension, we evaluated the responses to ANG II infusion (65 ng/min; osmotic mini-pump) for 2 weeks in rats treated with or without apocynin (APO) (inhibitor of Nox subunits assembly) in drinking water (12 mmol/L)." | 3.73 | Oxidant stress and blood pressure responses to angiotensin II administration in rats fed varying salt diets. ( Majid, DS; Pech, V; Sikka, SC; Sindhu, RK; Vaziri, ND, 2006) |
| "We recently reported that arterial superoxide (O2-) is augmented by increased endothelin-1 (ET-1) in deoxycorticosterone acetate (DOCA)-salt hypertension, a model of low renin hypertension." | 3.72 | Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension. ( Chen, AF; Fink, GD; Hesslinger, C; Kapatos, G; Kovesdi, I; Lookingland, KJ; Yang, XQ; Zheng, JS, 2003) |
| " Unfortunately, the treatment with CSA is often limited by severe adverse effects such as hypertension and nephrotoxicity." | 1.42 | The Protective Effect of Apocynin on Cyclosporine A-Induced Hypertension and Nephrotoxicity in Rats. ( Capasso, G; Ciarcia, R; Damiano, S; Florio, A; Florio, S; Garofano, T; Giordano, A; Mirabella, N; Pagnini, U; Polito, MS; Spagnuolo, M; Squillacioti, C; Zacchia, E, 2015) |
| "Preeclampsia is associated with oxidative stress, which is suspected to play a role in hypertension, placental ischemia, and fetal demise associated with the disease." | 1.40 | CD4+ T cells are important mediators of oxidative stress that cause hypertension in response to placental ischemia. ( Chatman, K; Cornelius, DC; Heath, J; LaMarca, B; Moseley, J; Scott, J; Wallace, K, 2014) |
| " Preincubation with sepiapterin (10 μmol/l for 30 min) failed to improve NO(·) bioavailability in hypertensive aortas while it augmented NO(·) production from control vessels, implicating a hypertension-associated deficiency in sepiapterin reductase (SPR), the rate-limiting enzyme for sepiapterin conversion to H(4)B." | 1.38 | Endothelium-specific sepiapterin reductase deficiency in DOCA-salt hypertension. ( Blair, J; Cai, H; Harrison, DG; Laude, KM; McCann, LA; Oak, JH; Wang, T; Youn, JY, 2012) |
| "Obesity is one of the major risk factors for cardiovascular disease and is often associated with increased oxidative stress and sympathoexcitation." | 1.35 | Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in obesity-induced hypertension. ( Ando, K; Fujita, M; Fujita, T; Kawarazaki, H; Matsui, H; Nagae, A, 2009) |
| "Candesartan treatment of DS rats with established diastolic heart failure reversed cardiac remodeling, improved cardiac relaxation abnormality, and prolonged survival, being accompanied by the attenuation of the increase in cardiac superoxide, reduced nicotinamide-adenine dinucleotide phosphate oxidase, and xanthine oxidoreductase activities." | 1.34 | Role of xanthine oxidoreductase in the reversal of diastolic heart failure by candesartan in the salt-sensitive hypertensive rat. ( Dong, YF; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Ogawa, H; Tokutomi, Y; Yamamoto, E; Yamashita, T, 2007) |
| "Enalapril prevented the increase in heart weight index (HWI), carotid cross-sectional area (CSA) and albuminuria induced by Ang II." | 1.33 | Prevention and reversal by enalapril of target organ damage in angiotensin II hypertension. ( Cordaillat, M; Jover, B; Mimran, A; Rugale, C, 2005) |
| "Hypertension is associated with increased reactive oxygen species (ROS)." | 1.33 | Increased reactive oxygen species contributes to kidney injury in mineralocorticoid hypertensive rats. ( Beswick, RA; Brands, MW; Jin, L; Palmer, T; Pollock, DM; Pollock, JS; Taylor, TA; Webb, RC; Yamamoto, T, 2006) |
| "Hypertension was induced in rats by abdominal aortic banding (Ab)." | 1.32 | Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system. ( Csiszar, A; Kaminski, PM; Koller, A; Ungvari, Z; Wolin, MS, 2004) |
| "Increased bioavailability of reactive oxygen species (ROS) has been implicated in the pathogenesis of mineralocorticoid hypertension." | 1.32 | NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats. ( Park, JB; Park, MY; Park, YM; Suh, YL, 2004) |
| " Superoxide anion (O(2)(-)) is a major determinant of nitric oxide (NO) bioavailability and thus endothelial function." | 1.31 | Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. ( Brosnan, MJ; Dominiczak, AF; Graham, D; Hamilton, CA; McIntyre, M, 2001) |
| " Moreover, long-term administration of apocynin (in drinking water, 1." | 1.31 | NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat. ( Beswick, RA; Dorrance, AM; Leite, R; Webb, RC, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 46 (53.49) | 29.6817 |
| 2010's | 35 (40.70) | 24.3611 |
| 2020's | 5 (5.81) | 2.80 |
| Authors | Studies |
|---|---|
| Marques, SM | 1 |
| Melo, MR | 1 |
| Zoccal, DB | 1 |
| Menani, JV | 1 |
| Colombari, DSA | 1 |
| Ferreira-Neto, ML | 1 |
| Xavier, CH | 1 |
| Colombari, E | 1 |
| Pedrino, GR | 1 |
| Robles-Vera, I | 1 |
| Visitación, N | 1 |
| Toral, M | 1 |
| Sánchez, M | 2 |
| Gómez-Guzmán, M | 1 |
| O'valle, F | 2 |
| Jiménez, R | 2 |
| Duarte, J | 2 |
| Romero, M | 2 |
| Wang, Q | 1 |
| Deng, F | 1 |
| Zhu, D | 1 |
| Tan, YC | 1 |
| Abdul Sattar, M | 1 |
| Ahmeda, AF | 1 |
| Abdul Karim Khan, N | 1 |
| Murugaiyah, V | 2 |
| Ahmad, A | 2 |
| Hassan, Z | 2 |
| Kaur, G | 2 |
| Abdulla, MH | 2 |
| Johns, EJ | 2 |
| Chia, TY | 1 |
| Khan, NA | 1 |
| Sattar, MA | 1 |
| Mei, HY | 1 |
| Ahmad, FU | 1 |
| Akhtar, S | 2 |
| Vieira, LD | 1 |
| Farias, JS | 1 |
| de Queiroz, DB | 1 |
| Cabral, EV | 1 |
| Lima-Filho, MM | 1 |
| Sant'Helena, BRM | 1 |
| Aires, RS | 1 |
| Ribeiro, VS | 1 |
| Santos-Rocha, J | 1 |
| Xavier, FE | 1 |
| Paixão, AD | 1 |
| Zhao, Y | 1 |
| Li, Y | 1 |
| Li, Z | 1 |
| Xu, B | 1 |
| Chen, P | 1 |
| Yang, X | 1 |
| Reckelhoff, JF | 3 |
| Romero, DG | 1 |
| Yanes Cardozo, LL | 1 |
| Stec, DE | 1 |
| Storm, MV | 1 |
| Pruett, BE | 1 |
| Gousset, MU | 1 |
| Nwokocha, CR | 1 |
| Baker, A | 1 |
| Douglas, D | 1 |
| McCalla, G | 1 |
| Nwokocha, M | 1 |
| Brown, PD | 1 |
| Schulz, R | 1 |
| Murzabekova, G | 1 |
| Egemnazarov, B | 1 |
| Kraut, S | 1 |
| Eisele, HJ | 1 |
| Dumitrascu, R | 1 |
| Heitmann, J | 1 |
| Seimetz, M | 1 |
| Witzenrath, M | 1 |
| Ghofrani, HA | 1 |
| Schermuly, RT | 1 |
| Grimminger, F | 1 |
| Seeger, W | 1 |
| Weissmann, N | 1 |
| Potje, SR | 3 |
| Hildebrand, MC | 1 |
| Munhoz, FC | 1 |
| Troiano, JA | 3 |
| Pereira, AA | 2 |
| Nakamune, AC | 2 |
| da Silva, RS | 1 |
| Bendhack, LM | 2 |
| Antoniali, C | 3 |
| Wallace, K | 1 |
| Cornelius, DC | 1 |
| Scott, J | 1 |
| Heath, J | 1 |
| Moseley, J | 1 |
| Chatman, K | 1 |
| LaMarca, B | 1 |
| Ciarcia, R | 2 |
| Damiano, S | 2 |
| Florio, A | 1 |
| Spagnuolo, M | 1 |
| Zacchia, E | 1 |
| Squillacioti, C | 1 |
| Mirabella, N | 1 |
| Florio, S | 2 |
| Pagnini, U | 1 |
| Garofano, T | 1 |
| Polito, MS | 1 |
| Capasso, G | 1 |
| Giordano, A | 1 |
| Perassa, LA | 1 |
| Graton, ME | 2 |
| Lima, MS | 1 |
| Vale, GT | 1 |
| Sumida, DH | 1 |
| Tirapelli, CR | 2 |
| Marchi, KC | 1 |
| Ceron, CS | 1 |
| Muniz, JJ | 1 |
| De Martinis, BS | 1 |
| Tanus-Santos, JE | 1 |
| Virdis, A | 2 |
| Gesi, M | 1 |
| Taddei, S | 1 |
| Rosa, CM | 1 |
| Gimenes, R | 1 |
| Campos, DH | 1 |
| Guirado, GN | 1 |
| Gimenes, C | 1 |
| Fernandes, AA | 1 |
| Cicogna, AC | 1 |
| Queiroz, RM | 1 |
| Falcão-Pires, I | 1 |
| Miranda-Silva, D | 1 |
| Rodrigues, P | 1 |
| Laurindo, FR | 2 |
| Fernandes, DC | 2 |
| Correa, CR | 1 |
| Okoshi, MP | 1 |
| Okoshi, K | 1 |
| Zahid, HM | 1 |
| Ferdaus, MZ | 1 |
| Ohara, H | 1 |
| Isomura, M | 1 |
| Nabika, T | 1 |
| Ximenes, VF | 1 |
| Nakamune, ACMS | 1 |
| Sousa, T | 1 |
| Pinho, D | 1 |
| Morato, M | 1 |
| Marques-Lopes, J | 1 |
| Fernandes, E | 1 |
| Afonso, J | 1 |
| Oliveira, S | 1 |
| Carvalho, F | 1 |
| Albino-Teixeira, A | 1 |
| Tabet, F | 1 |
| Schiffrin, EL | 2 |
| Callera, GE | 1 |
| He, Y | 1 |
| Yao, G | 1 |
| Ostman, A | 1 |
| Kappert, K | 1 |
| Tonks, NK | 1 |
| Touyz, RM | 3 |
| Schlüter, T | 1 |
| Steinbach, AC | 1 |
| Steffen, A | 1 |
| Rettig, R | 1 |
| Grisk, O | 1 |
| Yamamoto, E | 3 |
| Tamamaki, N | 1 |
| Nakamura, T | 1 |
| Kataoka, K | 3 |
| Tokutomi, Y | 3 |
| Dong, YF | 3 |
| Fukuda, M | 1 |
| Matsuba, S | 3 |
| Ogawa, H | 3 |
| Kim-Mitsuyama, S | 3 |
| Tian, N | 1 |
| Moore, RS | 1 |
| Phillips, WE | 1 |
| Lin, L | 1 |
| Braddy, S | 1 |
| Pryor, JS | 1 |
| Stockstill, RL | 1 |
| Hughson, MD | 1 |
| Manning, RD | 1 |
| Liu, F | 1 |
| Wei, CC | 1 |
| Wu, SJ | 1 |
| Chenier, I | 1 |
| Zhang, SL | 1 |
| Filep, JG | 1 |
| Ingelfinger, JR | 1 |
| Chan, JS | 1 |
| Carlström, M | 1 |
| Lai, EY | 1 |
| Ma, Z | 1 |
| Patzak, A | 1 |
| Brown, RD | 1 |
| Persson, AE | 1 |
| Stefanska, J | 1 |
| Pawliczak, R | 1 |
| Park, YM | 2 |
| Lim, BH | 1 |
| Park, JB | 2 |
| Liu, HG | 1 |
| Liu, K | 1 |
| Zhou, YN | 1 |
| Xu, YJ | 1 |
| Nagae, A | 1 |
| Fujita, M | 1 |
| Kawarazaki, H | 1 |
| Matsui, H | 1 |
| Ando, K | 2 |
| Fujita, T | 2 |
| Qian, JS | 1 |
| Pang, RP | 1 |
| Zhu, KS | 1 |
| Liu, DY | 1 |
| Li, ZR | 1 |
| Deng, CY | 1 |
| Wang, SM | 1 |
| Zhang, ZH | 1 |
| Yu, Y | 1 |
| Wei, SG | 1 |
| Felder, RB | 1 |
| Mazor, R | 2 |
| Itzhaki, O | 1 |
| Sela, S | 2 |
| Yagil, Y | 2 |
| Cohen-Mazor, M | 2 |
| Yagil, C | 2 |
| Kristal, B | 2 |
| Demel, SL | 1 |
| Dong, H | 1 |
| Swain, GM | 1 |
| Wang, X | 1 |
| Kreulen, DL | 1 |
| Galligan, JJ | 3 |
| Dhaunsi, GS | 1 |
| Yousif, MH | 1 |
| Chappell, MC | 1 |
| Diz, DI | 1 |
| Benter, IF | 1 |
| Panico, C | 1 |
| Scanni, R | 1 |
| Fiorito, F | 1 |
| Welch, JW | 1 |
| Buday, A | 1 |
| Orsy, P | 1 |
| Godó, M | 1 |
| Mózes, M | 1 |
| Kökény, G | 1 |
| Lacza, Z | 1 |
| Koller, A | 2 |
| Ungvári, Z | 2 |
| Gross, ML | 1 |
| Benyó, Z | 1 |
| Hamar, P | 1 |
| Kopkan, L | 1 |
| Hess, A | 1 |
| Husková, Z | 1 |
| Cervenka, L | 1 |
| Navar, LG | 1 |
| Majid, DS | 2 |
| Gayen, JR | 1 |
| Zhang, K | 1 |
| RamachandraRao, SP | 1 |
| Mahata, M | 1 |
| Chen, Y | 1 |
| Kim, HS | 1 |
| Naviaux, RK | 1 |
| Sharma, K | 1 |
| Mahata, SK | 1 |
| O'Connor, DT | 1 |
| Zhang, A | 1 |
| Jia, Z | 1 |
| Wang, N | 1 |
| Tidwell, TJ | 1 |
| Yang, T | 2 |
| Xiao, D | 1 |
| Huang, X | 1 |
| Yang, S | 1 |
| Zhang, L | 1 |
| Tain, YL | 1 |
| Hsu, CN | 1 |
| Huang, LT | 1 |
| Lau, YT | 1 |
| Senejoux, F | 1 |
| Girard-Thernier, C | 1 |
| Berthelot, A | 1 |
| Bévalot, F | 1 |
| Demougeot, C | 1 |
| Guimarães, DD | 1 |
| Carvalho, CC | 1 |
| Braga, VA | 1 |
| Mathis, KW | 1 |
| Venegas-Pont, M | 1 |
| Masterson, CW | 1 |
| Stewart, NJ | 1 |
| Wasson, KL | 1 |
| Ryan, MJ | 1 |
| Campuzano, V | 1 |
| Segura-Puimedon, M | 1 |
| Terrado, V | 1 |
| Sánchez-Rodríguez, C | 1 |
| Coustets, M | 1 |
| Menacho-Márquez, M | 1 |
| Nevado, J | 1 |
| Bustelo, XR | 1 |
| Francke, U | 1 |
| Pérez-Jurado, LA | 1 |
| Youn, JY | 1 |
| Wang, T | 1 |
| Blair, J | 1 |
| Laude, KM | 1 |
| Oak, JH | 1 |
| McCann, LA | 1 |
| Harrison, DG | 2 |
| Cai, H | 1 |
| Kishi, T | 1 |
| Hirooka, Y | 1 |
| Sunagawa, K | 1 |
| Martínez-Revelles, S | 1 |
| Avendaño, MS | 1 |
| García-Redondo, AB | 1 |
| Alvarez, Y | 1 |
| Aguado, A | 1 |
| Pérez-Girón, JV | 1 |
| García-Redondo, L | 1 |
| Esteban, V | 1 |
| Redondo, JM | 1 |
| Alonso, MJ | 1 |
| Briones, AM | 1 |
| Salaices, M | 1 |
| Chen, QZ | 1 |
| Han, WQ | 1 |
| Chen, J | 1 |
| Zhu, DL | 1 |
| Gao, PJ | 1 |
| Sharma, B | 1 |
| Singh, N | 1 |
| Li, L | 1 |
| Watts, SW | 1 |
| Banes, AK | 1 |
| Fink, GD | 3 |
| Chen, AF | 2 |
| Zheng, JS | 1 |
| Yang, XQ | 1 |
| Lookingland, KJ | 1 |
| Hesslinger, C | 1 |
| Kapatos, G | 1 |
| Kovesdi, I | 1 |
| Park, MY | 1 |
| Suh, YL | 1 |
| Xu, H | 1 |
| Neves, MF | 1 |
| Amiri, F | 1 |
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| Pollock, JS | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Antioxidant Activity of Lutein/Zeaxanthin Early Administered to Premature Newborns[NCT03340103] | 0 participants (Actual) | Interventional | 2018-10-11 | Withdrawn (stopped due to Recruitment was not possible) | |||
| The Effect of Pomegranate Juice on Oxidative Stress Biomarkers During Treatment With IV Iron During One Dialysis Session[NCT02107053] | 25 participants (Actual) | Interventional | 2014-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for acetovanillone and Blood Pressure, High
| Article | Year |
|---|---|
Sex, Oxidative Stress, and Hypertension: Insights From Animal Models.
Topics: Acetophenones; Animals; Antioxidants; Cyclic N-Oxides; Disease Models, Animal; Female; Humans; Hyper | 2019 |
Impact of apocynin on vascular disease in hypertension.
Topics: Acetophenones; Animals; Antioxidants; Humans; Hypertension; NADPH Oxidases; Oxidative Stress; Oxygen | 2016 |
Apocynin: molecular aptitudes.
Topics: Acetophenones; Animals; Arteriosclerosis; Asthma; Cartilage; Cyclooxygenase 2; Free Radical Scavenge | 2008 |
Sex differences in oxidative stress and the impact on blood pressure control and cardiovascular disease.
Topics: Acetophenones; Animals; Antioxidants; Ascorbic Acid; Blood Pressure; Cardiovascular Diseases; Catala | 2007 |
82 other studies available for acetovanillone and Blood Pressure, High
| Article | Year |
|---|---|
Acute inhibition of nicotinamide adenine dinucleotide phosphate oxidase in the commissural nucleus of the solitary tract reduces arterial pressure and renal sympathetic nerve activity in renovascular hypertension.
Topics: Animals; Arterial Pressure; Blood Pressure; Hypertension; Hypertension, Renovascular; Kidney; Male; | 2023 |
Toll-like receptor 7-driven lupus autoimmunity induces hypertension and vascular alterations in mice.
Topics: Acetophenones; Animals; Antioxidants; Autoantibodies; Autoimmunity; Blood Pressure; Blood Pressure D | 2020 |
Superoxide anions modulate the effects of alarin in the paraventricular nucleus on sympathetic activity and blood pressure in spontaneously hypertensive rats.
Topics: Acetophenones; Animals; Arterial Pressure; Blood Pressure; Cyclic N-Oxides; Galanin-Like Peptide; He | 2020 |
Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats.
Topics: Acetophenones; Acute Kidney Injury; Animals; Catalase; Cyclosporine; Hemodynamics; Hypertension; Kid | 2020 |
Inhibition of L-NAME-induced hypertension by combined treatment with apocynin and catalase: the role of Nox 4 expression.
Topics: Acetophenones; Animals; Antioxidants; Catalase; Disease Models, Animal; Drug Therapy, Combination; E | 2021 |
Oxidative stress induced by prenatal LPS leads to endothelial dysfunction and renal haemodynamic changes through angiotensin II/NADPH oxidase pathway: Prevention by early treatment with α-tocopherol.
Topics: Acetophenones; alpha-Tocopherol; Angiotensin II; Animals; Antioxidants; Blood Pressure; Female; Hemo | 2018 |
Superoxide anions modulate the performance of apelin in the paraventricular nucleus on sympathetic activity and blood pressure in spontaneously hypertensive rats.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetophenones; Animals; Apelin; Apelin Recep | 2019 |
Antihypertensive actions of moderate hyperbilirubinemia: role of superoxide inhibition.
Topics: Acetophenones; Angiotensin II; Animals; Bilirubin; Blood Pressure; Disease Models, Animal; Drug Impl | 2013 |
Apocynin ameliorates cadmium-induced hypertension through elevation of endothelium nitric oxide synthase.
Topics: Acetophenones; Anemia; Animals; Blood Pressure; Cadmium; Enzyme Inhibitors; Hypertension; Male; Nitr | 2013 |
Arterial hypertension in a murine model of sleep apnea: role of NADPH oxidase 2.
Topics: Acetophenones; Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Mal | 2014 |
The hypotensive effect of the ruthenium complex [Ru(terpy)(bdq)NO]³⁺ is higher in male than in female spontaneously hypertensive rats (SHR).
Topics: Acetophenones; Animals; Blood Pressure; Cyclic N-Oxides; Female; Hypertension; Male; NG-Nitroarginin | 2014 |
CD4+ T cells are important mediators of oxidative stress that cause hypertension in response to placental ischemia.
Topics: Acetophenones; Adolescent; Adult; Animals; Antioxidants; CD4-Positive T-Lymphocytes; Cells, Cultured | 2014 |
The Protective Effect of Apocynin on Cyclosporine A-Induced Hypertension and Nephrotoxicity in Rats.
Topics: Acetophenones; Animals; Blood Pressure; Cyclosporine; Enzyme Inhibitors; Glomerular Filtration Rate; | 2015 |
Apocynin reduces blood pressure and restores the proper function of vascular endothelium in SHR.
Topics: Acetophenones; Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Calcium; Endothelial Cells; | 2016 |
NADPH Oxidase Plays a Role on Ethanol-Induced Hypertension and Reactive Oxygen Species Generation in the Vasculature.
Topics: Acetophenones; Animals; Blood Pressure; Endothelium, Vascular; Ethanol; Glutathione; Hydrogen Peroxi | 2016 |
Apocynin influence on oxidative stress and cardiac remodeling of spontaneously hypertensive rats with diabetes mellitus.
Topics: Acetophenones; Animals; Antioxidants; Catalase; Collagen Type III; Diabetes Mellitus, Experimental; | 2016 |
Effect of p22phox depletion on sympathetic regulation of blood pressure in SHRSP: evaluation in a new congenic strain.
Topics: Acetophenones; Animals; Animals, Congenic; Antioxidants; Blood Pressure; Brain Stem; Cold Temperatur | 2016 |
Hypotensive and vasorelaxant effect of Diapocynin in normotensive rats.
Topics: Acetophenones; Animals; Antioxidants; Aorta; Biphenyl Compounds; Blood Pressure; Calcium; Endothelia | 2017 |
Role of superoxide and hydrogen peroxide in hypertension induced by an antagonist of adenosine receptors.
Topics: Acetophenones; Animals; Blood Vessels; Catalase; Hydrogen Peroxide; Hypertension; Lipid Peroxidation | 2008 |
Redox-sensitive signaling by angiotensin II involves oxidative inactivation and blunted phosphorylation of protein tyrosine phosphatase SHP-2 in vascular smooth muscle cells from SHR.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetophenones; Angiotensin II; Animals; Cell | 2008 |
Apocynin-induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition.
Topics: Acetophenones; Age Factors; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relations | 2008 |
Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.
Topics: Acetophenones; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Astrocytes; Blood Pressu | 2008 |
NADPH oxidase contributes to renal damage and dysfunction in Dahl salt-sensitive hypertension.
Topics: Acetophenones; Allopurinol; Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Gene | 2008 |
Apocynin attenuates tubular apoptosis and tubulointerstitial fibrosis in transgenic mice independent of hypertension.
Topics: Acetophenones; Animals; Apoptosis; Fibrosis; Hypertension; Kidney Tubules; Mice; Mice, Transgenic; N | 2009 |
Role of NOX2 in the regulation of afferent arteriole responsiveness.
Topics: Acetophenones; Adenosine; Angiotensin II; Animals; Arterioles; Blood Pressure; Disease Models, Anima | 2009 |
Expression of NAD(P)H oxidase subunits and their contribution to cardiovascular damage in aldosterone/salt-induced hypertensive rat.
Topics: Acetophenones; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agen | 2008 |
[Effect of NADPH oxidase activity inhibitor apocynin on blood pressure in rats exposed to chronic intermittent hypoxia and the possible mechanisms].
Topics: Acetophenones; Animals; Blood Pressure; Enzyme Inhibitors; Hypertension; Hypoxia; Male; NADPH Oxidas | 2008 |
Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in obesity-induced hypertension.
Topics: Acetophenones; Animals; Blood Pressure; Brain; Cyclic N-Oxides; Heart Rate; Hexamethonium; Hypertens | 2009 |
Static pressure promotes rat aortic smooth muscle cell proliferation via upregulation of volume-regulated chloride channel.
Topics: Acetophenones; Animals; Aorta; Cell Proliferation; Chloride Channels; Gene Knockdown Techniques; Hyp | 2009 |
Centrally administered lipopolysaccharide elicits sympathetic excitation via NAD(P)H oxidase-dependent mitogen-activated protein kinase signaling.
Topics: Acetophenones; Animals; Blood Pressure; Cyclic N-Oxides; Cyclooxygenase 2; Heart Failure; Heart Rate | 2010 |
Tumor necrosis factor-alpha: a possible priming agent for the polymorphonuclear leukocyte-reduced nicotinamide-adenine dinucleotide phosphate oxidase in hypertension.
Topics: Acetophenones; Analysis of Variance; Animals; Blood Pressure Determination; Cytokines; Disease Model | 2010 |
Antioxidant treatment restores prejunctional regulation of purinergic transmission in mesenteric arteries of deoxycorticosterone acetate-salt hypertensive rats.
Topics: Acetophenones; Adenosine Triphosphate; Animals; Antioxidants; Calcium Channel Blockers; Calcium Chan | 2010 |
Angiotensin-(1-7) prevents diabetes-induced attenuation in PPAR-gamma and catalase activities.
Topics: Acetophenones; Angiotensin I; Animals; Antihypertensive Agents; Antioxidants; Blood Glucose; Blood P | 2010 |
Apocynin activity in spontaneously hypertensive rats (SHR): preliminary studies in vivo.
Topics: Acetophenones; Animals; Antihypertensive Agents; Enzyme Inhibitors; Hypertension; Male; Rats; Rats, | 2010 |
Elevated systemic TGF-beta impairs aortic vasomotor function through activation of NADPH oxidase-driven superoxide production and leads to hypertension, myocardial remodeling, and increased plaque formation in apoE(-/-) mice.
Topics: Acetophenones; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Body Weight; Card | 2010 |
High-salt intake enhances superoxide activity in eNOS knockout mice leading to the development of salt sensitivity.
Topics: Acetophenones; Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Dinoprost; Disease Models, An | 2010 |
Role of reactive oxygen species in hyperadrenergic hypertension: biochemical, physiological, and pharmacological evidence from targeted ablation of the chromogranin a (Chga) gene.
Topics: Acetophenones; Adrenocortical Hyperfunction; Animals; Antihypertensive Agents; Blood Pressure; Catec | 2010 |
Relative contributions of mitochondria and NADPH oxidase to deoxycorticosterone acetate-salt hypertension in mice.
Topics: Acetophenones; Albuminuria; Aldosterone; Animals; Blood Pressure; Cell Line; Desoxycorticosterone; D | 2011 |
Antenatal nicotine induces heightened oxidative stress and vascular dysfunction in rat offspring.
Topics: Acetophenones; Angiotensin II; Animals; Aorta; Blotting, Western; Cyclic N-Oxides; Dose-Response Rel | 2011 |
Apocynin attenuates oxidative stress and hypertension in young spontaneously hypertensive rats independent of ADMA/NO pathway.
Topics: Acetophenones; Animals; Antioxidants; Arginine; Hypertension; Male; NADPH Oxidases; Nitric Oxide; Ox | 2012 |
New insights into the mechanisms of the vasorelaxant effects of apocynin in rat thoracic aorta.
Topics: Acetophenones; Animals; Antihypertensive Agents; Aorta, Thoracic; Calcium; Dose-Response Relationshi | 2013 |
Scavenging of NADPH oxidase-derived superoxide anions improves depressed baroreflex sensitivity in spontaneously hypertensive rats.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetophenones; Animals; Baroreflex; Free Rad | 2012 |
Oxidative stress promotes hypertension and albuminuria during the autoimmune disease systemic lupus erythematosus.
Topics: Acetophenones; Albuminuria; Animals; Antioxidants; Autoimmunity; Blood Pressure; Cyclic N-Oxides; Di | 2012 |
Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.
Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Blood Pre | 2012 |
Endothelium-specific sepiapterin reductase deficiency in DOCA-salt hypertension.
Topics: Acetophenones; Alcohol Oxidoreductases; Animals; Aorta; Biopterins; Blood Pressure; Desoxycorticoste | 2012 |
Sympathoinhibition caused by orally administered telmisartan through inhibition of the AT₁ receptor in the rostral ventrolateral medulla of hypertensive rats.
Topics: Acetophenones; Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertens | 2012 |
Reciprocal relationship between reactive oxygen species and cyclooxygenase-2 and vascular dysfunction in hypertension.
Topics: Acetophenones; Animals; Antioxidants; Aorta; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxy | 2013 |
Anti-stiffness effect of apocynin in deoxycorticosterone acetate-salt hypertensive rats via inhibition of oxidative stress.
Topics: Acetophenones; Animals; Antioxidants; Aorta, Thoracic; Blood Pressure; Carotid Arteries; Collagen; D | 2013 |
Pharmacological inhibition of inducible nitric oxide synthase (iNOS) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, convalesce behavior and biochemistry of hypertension induced vascular dementia in rats.
Topics: Acetophenones; Animals; Brain Chemistry; Convalescence; Dementia, Vascular; Guanidines; Hypertension | 2013 |
NADPH oxidase-derived superoxide augments endothelin-1-induced venoconstriction in mineralocorticoid hypertension.
Topics: Acetophenones; Allopurinol; Animals; Atrasentan; Desoxycorticosterone; Dose-Response Relationship, D | 2003 |
Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.
Topics: Acetophenones; Animals; Antioxidants; Atrasentan; Biopterins; Carotid Arteries; Cyclic N-Oxides; Des | 2003 |
NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats.
Topics: Acetophenones; Aldosterone; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Collagen; Fibro | 2004 |
Tempol lowers blood pressure and sympathetic nerve activity but not vascular O2- in DOCA-salt rats.
Topics: Acetophenones; Animals; Antioxidants; Aorta; Blood Pressure; Cyclic N-Oxides; Desoxycorticosterone; | 2004 |
Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice.
Topics: Acetophenones; Angiotensin II; Animals; Blood Pressure; Body Weight; Collagen; Endothelium, Vascular | 2004 |
Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.
Topics: Acetophenones; Acetylcholine; Alkaloids; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; A | 2004 |
Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetophenones; Amino Acid Sequence; Angioten | 2004 |
NADPH oxidase inhibition attenuates oxidative stress but not hypertension produced by chronic ET-1.
Topics: Acetophenones; Animals; Antioxidants; Cyclic N-Oxides; Drug Administration Schedule; Endothelin-1; E | 2005 |
Angiotensin II-induced over-activation of p47phox in fibroblasts from hypertensives: which role in the enhanced ERK1/2 responsiveness to angiotensin II?
Topics: Acetophenones; Adult; Angiotensin II; Antioxidants; Cell Membrane; Cells, Cultured; Cytosol; Fibrobl | 2005 |
Antioxidant treatment normalizes nitric oxide production, renal sodium handling and blood pressure in experimental hyperleptinemia.
Topics: Acetophenones; Aconitate Hydratase; Aldehydes; Animals; Antioxidants; Blood Pressure; Body Weight; C | 2005 |
Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Biopterins; Cardiomegaly; Dis | 2005 |
Apocynin but not allopurinol prevents and reverses adrenocorticotropic hormone-induced hypertension in the rat.
Topics: Acetophenones; Adrenocorticotropic Hormone; Allopurinol; Animals; Antihypertensive Agents; Antioxida | 2005 |
Effect of apocynin treatment on renal expression of COX-2, NOS1, and renin in Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Acetophenones; Animals; Blood Pressure; Cyclooxygenase 1; Cyclooxygenase 2; Gene Expression Regulati | 2006 |
NADPH oxidase in the renal medulla causes oxidative stress and contributes to salt-sensitive hypertension in Dahl S rats.
Topics: Acetophenones; Animals; Catalase; Chromosomes, Mammalian; Drug Resistance; Enzyme Inhibitors; Glutat | 2006 |
Prevention and reversal by enalapril of target organ damage in angiotensin II hypertension.
Topics: Acetophenones; Albuminuria; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti- | 2005 |
Apocynin but not L-arginine prevents and reverses dexamethasone-induced hypertension in the rat.
Topics: Acetophenones; Animals; Arginine; Blood Pressure; Dexamethasone; Endothelium, Vascular; Enzyme Inhib | 2006 |
Oxidant stress and blood pressure responses to angiotensin II administration in rats fed varying salt diets.
Topics: Acetophenones; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Diet, Sodium-Restricted; | 2006 |
Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation.
Topics: Acetophenones; Acetylcholine; Animals; Aorta, Thoracic; Apolipoproteins E; Bone Morphogenetic Protei | 2006 |
Impact of androgen-induced oxidative stress on hypertension in male SHR.
Topics: Acetophenones; Acridines; Androgens; Animals; Blood Pressure; Body Weight; Enzyme Inhibitors; Hypert | 2007 |
Vascular lipotoxicity: endothelial dysfunction via fatty-acid-induced reactive oxygen species overproduction in obese Zucker diabetic fatty rats.
Topics: Acetophenones; Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Dyslipidemias; Endothelium, Vasc | 2007 |
Increased reactive oxygen species contributes to kidney injury in mineralocorticoid hypertensive rats.
Topics: Acetophenones; Animals; Antioxidants; Blood Pressure; Desoxycorticosterone; Histocytochemistry; Hype | 2006 |
Long-term effects of intrauterine malnutrition on vascular function in female offspring: implications of oxidative stress.
Topics: Acetophenones; Animals; Animals, Newborn; Arterioles; Blood Pressure; Drug Interactions; Endothelium | 2007 |
Polyphenols restore endothelial function in DOCA-salt hypertension: role of endothelin-1 and NADPH oxidase.
Topics: Acetophenones; Animals; Blood Pressure; Desoxycorticosterone; Endothelin-1; Endothelium, Vascular; F | 2007 |
The NAD(P)H oxidase inhibitor apocynin improves endothelial NO/superoxide balance and lowers effectively blood pressure in spontaneously hypertensive rats: comparison to calcium channel blockade.
Topics: Acetophenones; Animals; Blood Pressure; Calcium Channel Blockers; Endothelium, Vascular; Enzyme Inhi | 2007 |
Angiotensin II chronic infusion induces B1 receptor expression in aorta of rats.
Topics: Acetophenones; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, | 2007 |
Role of xanthine oxidoreductase in the reversal of diastolic heart failure by candesartan in the salt-sensitive hypertensive rat.
Topics: Acetophenones; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; | 2007 |
Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine.
Topics: Acetophenones; Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Cardiome | 2007 |
The polymorphonuclear leukocyte contributes to the development of hypertension in the Sabra rat.
Topics: Acetophenones; Animals; Blood Pressure; CD11b Antigen; Disease Models, Animal; Hypertension; Leukocy | 2007 |
Novel mechanism and role of angiotensin II induced vascular endothelial injury in hypertensive diastolic heart failure.
Topics: Acetophenones; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihyp | 2007 |
Protective effect of dietary potassium against vascular injury in salt-sensitive hypertension.
Topics: Acetophenones; Animals; Antioxidants; Constriction; Cyclic N-Oxides; Femoral Artery; Hypertension; I | 2008 |
H2O2 stimulation of the Cl-/HCO3- exchanger by angiotensin II and angiotensin II type 1 receptor distribution in membrane microdomains.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Cell Membrane; Cells, Cultured; Chloride-Bicar | 2008 |
Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction.
Topics: Acetophenones; Aging; Animals; Aorta; Blood Pressure; Carotid Arteries; Endothelium, Vascular; Enzym | 2001 |
NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat.
Topics: Acetophenones; Animals; Aorta; Blood Pressure; Culture Techniques; Desoxycorticosterone; Enzyme Inhi | 2001 |