acetovanillone has been researched along with Asthma in 7 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| " At 36 h before and 16 h after O(3) exposure, methacholine inhalation challenge tests (Mch) were performed, and PC(20) and maximal % fall from baseline (MFEV(1)) were calculated from dose-response curves." | 6.70 | Effect of apocynin on ozone-induced airway hyperresponsiveness to methacholine in asthmatics. ( Hiltermann, JT; Peters, EA; Stolk, J, 2001) |
| " At 36 h before and 16 h after O(3) exposure, methacholine inhalation challenge tests (Mch) were performed, and PC(20) and maximal % fall from baseline (MFEV(1)) were calculated from dose-response curves." | 2.70 | Effect of apocynin on ozone-induced airway hyperresponsiveness to methacholine in asthmatics. ( Hiltermann, JT; Peters, EA; Stolk, J, 2001) |
| "Obesity is already responsible for 300,000 deaths per year." | 1.51 | The influence of apocynin, lipoic acid and probiotics on antioxidant enzyme levels in the pulmonary tissues of obese asthmatic mice. ( Kleniewska, P; Pawliczak, R, 2019) |
| "Apocynin also significantly reduced lung inflammation in the tissues." | 1.38 | Anti-inflammatory effects of apocynin, an inhibitor of NADPH oxidase, in airway inflammation. ( Cho, YS; Chun, E; Jeong, S; Jo, HY; Jung, E; Kim, SY; Lee, KY; Moon, KA; Seon, SH, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kleniewska, P | 1 |
| Pawliczak, R | 3 |
| Chan, TK | 1 |
| Tan, WSD | 1 |
| Peh, HY | 1 |
| Wong, WSF | 1 |
| Stefanska, J | 2 |
| Kim, SY | 1 |
| Moon, KA | 1 |
| Jo, HY | 1 |
| Jeong, S | 1 |
| Seon, SH | 1 |
| Jung, E | 1 |
| Cho, YS | 1 |
| Chun, E | 1 |
| Lee, KY | 1 |
| Sarniak, A | 1 |
| Wlodarczyk, A | 1 |
| Sokolowska, M | 1 |
| Pniewska, E | 1 |
| Doniec, Z | 1 |
| Nowak, D | 1 |
| Thomas, M | 1 |
| Sheran, J | 1 |
| Smith, N | 1 |
| Fonseca, S | 1 |
| Lee, AJ | 1 |
| Peters, EA | 1 |
| Hiltermann, JT | 1 |
| Stolk, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Investigation of the Safety and Efficacy of Oral AKL1 in Patients Diagnosed With Obstructive Lung Disease[NCT00920127] | Phase 2/Phase 3 | 164 participants (Anticipated) | Interventional | 2009-06-30 | Active, not recruiting | ||
| Inhaled Apocynin Decreases Reactive Oxygen Species Concentrations in Exhaled Breath Condensate in Mild Asthmatics[NCT00992667] | Phase 1 | 10 participants (Actual) | Interventional | 2008-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for acetovanillone and Asthma
| Article | Year |
|---|---|
Apocynin: molecular aptitudes.
Topics: Acetophenones; Animals; Arteriosclerosis; Asthma; Cartilage; Cyclooxygenase 2; Free Radical Scavenge | 2008 |
3 trials available for acetovanillone and Asthma
| Article | Year |
|---|---|
Apocynin reduces reactive oxygen species concentrations in exhaled breath condensate in asthmatics.
Topics: Acetophenones; Administration, Inhalation; Adult; Anti-Inflammatory Agents; Antioxidants; Asthma; Br | 2012 |
AKL1, a botanical mixture for the treatment of asthma: a randomised, double-blind, placebo-controlled, cross-over study.
Topics: Acetophenones; Adolescent; Adult; Aged; Asthma; Cross-Over Studies; Double-Blind Method; Ginkgo bilo | 2007 |
Effect of apocynin on ozone-induced airway hyperresponsiveness to methacholine in asthmatics.
Topics: Acetophenones; Administration, Inhalation; Adult; Aerosols; Antioxidants; Asthma; Bronchial Hyperrea | 2001 |
3 other studies available for acetovanillone and Asthma
| Article | Year |
|---|---|
The influence of apocynin, lipoic acid and probiotics on antioxidant enzyme levels in the pulmonary tissues of obese asthmatic mice.
Topics: Acetophenones; Animals; Antioxidants; Asthma; Catalase; Glutathione Peroxidase; Lung; Male; Mice, In | 2019 |
Aeroallergens Induce Reactive Oxygen Species Production and DNA Damage and Dampen Antioxidant Responses in Bronchial Epithelial Cells.
Topics: Acetophenones; Air; Allergens; Animals; Antioxidants; Apoptosis; Apoptosis Inducing Factor; Asthma; | 2017 |
Anti-inflammatory effects of apocynin, an inhibitor of NADPH oxidase, in airway inflammation.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Asthma; Cytokines; Humans; Inflammation Mediators; | 2012 |