acetovanillone has been researched along with Apoplexy in 15 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Despite comparable hypotensive effects between valsartan and hydralazine in salt-loaded SHRSP, valsartan reduced cerebral NADPH oxidase activity and ROS more than hydralazine being accompanied by more prevention of stroke by valsartan than hydralazine." | 7.74 | Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation. ( Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tamamaki, N; Tokutomi, Y; Yamamoto, E, 2008) |
| " Despite comparable hypotensive effects between valsartan and hydralazine in salt-loaded SHRSP, valsartan reduced cerebral NADPH oxidase activity and ROS more than hydralazine being accompanied by more prevention of stroke by valsartan than hydralazine." | 3.74 | Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation. ( Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tamamaki, N; Tokutomi, Y; Yamamoto, E, 2008) |
| "Stroke is a universal cause of death and permanent disability." | 1.46 | Adiponectin attenuates NADPH oxidase-mediated oxidative stress and neuronal damage induced by cerebral ischemia-reperfusion injury. ( Bai, H; Feng, D; Gao, L; Guo, H; Jiang, H; Li, X; Liu, H; Qu, Y; Wang, B; Yue, L; Zhao, L, 2017) |
| "The present study was designed to determine a dose-response relationship between apocynin and infarct volume as well as to provide a possible molecular mechanism mediating this effect." | 1.37 | Apocynin may limit total cell death following cerebral ischemia and reperfusion by enhancing apoptosis. ( Connell, BJ; Khan, BV; Saleh, MC; Saleh, TM, 2011) |
| "Risk of intracerebral hemorrhage is the primary factor limiting use of tissue plasminogen activator (tPA) for stroke." | 1.37 | Hyperglycemia promotes tissue plasminogen activator-induced hemorrhage by Increasing superoxide production. ( Suh, SW; Swanson, RA; Tang, XN; Won, SJ; Yenari, MA, 2011) |
| "This study utilized middle cerebral artery occlusion (MCAO) with tissue plasminogen activator (tPA) to assess inhibition of the NOX2 isoform of NADPH oxidase on brain injury and functional recovery in aged rats." | 1.35 | NOX2 inhibition with apocynin worsens stroke outcome in aged rats. ( Huber, JD; Kelly, KA; Li, X; Rosen, CL; Tan, Z; VanGilder, RL, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 9 (60.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Nakka, VP | 1 |
| Gogada, R | 1 |
| Simhadri, PK | 1 |
| Qadeer, MA | 1 |
| Phanithi, PB | 1 |
| Li, X | 2 |
| Guo, H | 1 |
| Zhao, L | 1 |
| Wang, B | 1 |
| Liu, H | 1 |
| Yue, L | 1 |
| Bai, H | 1 |
| Jiang, H | 1 |
| Gao, L | 1 |
| Feng, D | 1 |
| Qu, Y | 1 |
| Zahid, HM | 1 |
| Ferdaus, MZ | 1 |
| Ohara, H | 1 |
| Isomura, M | 1 |
| Nabika, T | 1 |
| Qin, YY | 1 |
| Li, M | 1 |
| Feng, X | 1 |
| Wang, J | 1 |
| Cao, L | 1 |
| Shen, XK | 1 |
| Chen, J | 3 |
| Sun, M | 1 |
| Sheng, R | 1 |
| Han, F | 1 |
| Qin, ZH | 1 |
| Tang, XN | 3 |
| Cairns, B | 1 |
| Cairns, N | 1 |
| Yenari, MA | 3 |
| Yamamoto, E | 1 |
| Tamamaki, N | 1 |
| Nakamura, T | 1 |
| Kataoka, K | 1 |
| Tokutomi, Y | 1 |
| Dong, YF | 1 |
| Fukuda, M | 1 |
| Matsuba, S | 1 |
| Ogawa, H | 1 |
| Kim-Mitsuyama, S | 1 |
| Kelly, KA | 1 |
| Tan, Z | 1 |
| VanGilder, RL | 1 |
| Rosen, CL | 1 |
| Huber, JD | 1 |
| Connell, BJ | 2 |
| Saleh, MC | 2 |
| Khan, BV | 2 |
| Saleh, TM | 2 |
| Won, SJ | 1 |
| Suh, SW | 1 |
| Swanson, RA | 1 |
| Zheng, Z | 1 |
| Giffard, RG | 1 |
| Rajagopal, D | 1 |
| Palomares, SM | 1 |
| Gardner-Morse, I | 1 |
| Sweet, JG | 1 |
| Cipolla, MJ | 1 |
| Xiao, X | 1 |
| Chen, S | 1 |
| Zhang, C | 1 |
| Yi, D | 1 |
| Shenoy, V | 1 |
| Raizada, MK | 1 |
| Zhao, B | 1 |
| Chen, Y | 1 |
| Sun, H | 1 |
| Zheng, H | 1 |
| Molacek, E | 1 |
| Fang, Q | 1 |
| Patel, KP | 1 |
| Mayhan, WG | 1 |
| Cui, C | 1 |
| Chen, AF | 1 |
| Jiang, Z | 1 |
| Wu, Q | 1 |
| Lin, J | 1 |
| Wen, H | 1 |
| Zeng, J | 1 |
15 other studies available for acetovanillone and Apoplexy
| Article | Year |
|---|---|
Post-treatment with apocynin at a lower dose regulates the UPR branch of eIF2α and XBP-1 pathways after stroke.
Topics: Acetophenones; Animals; Brain Injuries; Endoribonucleases; Eukaryotic Initiation Factor-2; Protein S | 2022 |
Adiponectin attenuates NADPH oxidase-mediated oxidative stress and neuronal damage induced by cerebral ischemia-reperfusion injury.
Topics: Acetophenones; Adiponectin; Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; DNA Nucleoti | 2017 |
Effect of p22phox depletion on sympathetic regulation of blood pressure in SHRSP: evaluation in a new congenic strain.
Topics: Acetophenones; Animals; Animals, Congenic; Antioxidants; Blood Pressure; Brain Stem; Cold Temperatur | 2016 |
Combined NADPH and the NOX inhibitor apocynin provides greater anti-inflammatory and neuroprotective effects in a mouse model of stroke.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Brain Ischemia; Cyclooxygenase 2; Disease Models, | 2017 |
Apocynin improves outcome in experimental stroke with a narrow dose range.
Topics: Acetophenones; Animals; Behavior, Animal; Blood-Brain Barrier; CD11b Antigen; Cerebral Infarction; D | 2008 |
Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.
Topics: Acetophenones; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Astrocytes; Blood Pressu | 2008 |
NOX2 inhibition with apocynin worsens stroke outcome in aged rats.
Topics: Acetophenones; Aging; Animals; Antioxidants; Blood-Brain Barrier; Brain; Capillary Permeability; Ede | 2009 |
Apocynin may limit total cell death following cerebral ischemia and reperfusion by enhancing apoptosis.
Topics: Acetophenones; Animals; Antioxidants; Apoptosis; Brain Ischemia; DNA Fragmentation; Dose-Response Re | 2011 |
Hyperglycemia promotes tissue plasminogen activator-induced hemorrhage by Increasing superoxide production.
Topics: Acetophenones; Animals; Antioxidants; Blood Glucose; Blood-Brain Barrier; Cerebral Hemorrhage; Disea | 2011 |
Significance of marrow-derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke.
Topics: Acetophenones; Animals; Bone Marrow Cells; Brain; Brain Ischemia; Enzyme Inhibitors; Male; Membrane | 2011 |
UPEI-100, a conjugate of lipoic acid and apocynin, mediates neuroprotection in a rat model of ischemia/reperfusion.
Topics: Acetophenones; Animals; Biomarkers; Disease Models, Animal; Glutathione Disulfide; Infarction, Middl | 2012 |
Peroxynitrite decomposition with FeTMPyP improves plasma-induced vascular dysfunction and infarction during mild but not severe hyperglycemic stroke.
Topics: Acetophenones; Animals; Brain Infarction; Enzyme Inhibitors; Hyperglycemia; Male; Metalloporphyrins; | 2012 |
Angiotensin-converting enzyme 2 priming enhances the function of endothelial progenitor cells and their therapeutic efficacy.
Topics: Acetophenones; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Cells, Cultured; Enzyme In | 2013 |
Role of NAD(P)H oxidase in alcohol-induced impairment of endothelial nitric oxide synthase-dependent dilation of cerebral arterioles.
Topics: Acetophenones; Acetylcholine; Acridines; Adenosine Diphosphate; Alcohol Drinking; Alcohols; Animals; | 2006 |
Inhibition of NAD(P)H oxidase reduces fibronectin expression in stroke-prone renovascular hypertensive rat brain.
Topics: Acetophenones; Administration, Oral; Amine Oxidase (Copper-Containing); Animals; Blood Pressure; Blo | 2007 |