acetovanillone has been researched along with Alloxan Diabetes in 40 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The flavanol-3-ol (-)-epicatechin (EC) can improve insulin sensitivity both in humans and animal models of T2D." | 7.88 | (-)-Epicatechin and its metabolites prevent palmitate-induced NADPH oxidase upregulation, oxidative stress and insulin resistance in HepG2 cells. ( Cremonini, E; Oteiza, PI, 2018) |
| "Apocynin, a NADPH oxidase inhibitor, prevents AF and attenuates atrial remodeling in alloxan-induced diabetic rabbits." | 7.83 | NADPH oxidase inhibitor apocynin prevents atrial remodeling in alloxan-induced diabetic rabbits. ( Fu, H; Korantzopoulos, P; Li, G; Li, J; Liang, X; Liu, T; Qiu, J; Yang, Y; Zhang, X; Zhang, Z; Zhao, J, 2016) |
| " The flavanol-3-ol (-)-epicatechin (EC) can improve insulin sensitivity both in humans and animal models of T2D." | 3.88 | (-)-Epicatechin and its metabolites prevent palmitate-induced NADPH oxidase upregulation, oxidative stress and insulin resistance in HepG2 cells. ( Cremonini, E; Oteiza, PI, 2018) |
| "Apocynin, a NADPH oxidase inhibitor, prevents AF and attenuates atrial remodeling in alloxan-induced diabetic rabbits." | 3.83 | NADPH oxidase inhibitor apocynin prevents atrial remodeling in alloxan-induced diabetic rabbits. ( Fu, H; Korantzopoulos, P; Li, G; Li, J; Liang, X; Liu, T; Qiu, J; Yang, Y; Zhang, X; Zhang, Z; Zhao, J, 2016) |
| "We studied whether angiotensin II (ANG II) via superoxide may contribute to retinal leukostasis and thus to the pathogenesis of retinopathies." | 3.74 | Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis. ( Chen, P; Edwards, PA; Guo, AM; Scicli, AG; Trick, G, 2007) |
| "Diabetic retinopathy is a diabetes complication." | 1.51 | Apocynin ameliorates diabetic retinopathy in rats: Involvement of TLR4/NF-κB signaling pathway. ( Jiang, M; Tao, J; Wang, Y; Yao, Y, 2019) |
| "In rats with diabetic nephropathy, apocynin (1) reduced renal injury and improved renal function; (2) downregulated the expression of NLRP3 in renal cortex; (3) downregulated the expression of XIAP in renal cortex; and (4) attenuated renal fibrosis." | 1.48 | Apocynin inhibited NLRP3/XIAP signalling to alleviate renal fibrotic injury in rat diabetic nephropathy. ( Du, P; Hou, Y; Jiang, W; Li, X; Sun, W; Sun, X; Wang, L; Wang, Z; Xiang, Y; Xin, R; Yuan, W; Zhang, H, 2018) |
| "Two hours after the end of EA pretreatment, focal cerebral ischemia was induced following 24h reperfusion." | 1.40 | Electroacupuncture pretreatment inhibits NADPH oxidase-mediated oxidative stress in diabetic mice with cerebral ischemia. ( Guo, F; Jiang, T; Liu, L; Song, W; Wang, F; Wang, Q; Xiong, L; Yin, H; Zhong, H, 2014) |
| "It may be concluded that STZ induces vascular dementia." | 1.36 | Pitavastatin and 4'-hydroxy-3'-methoxyacetophenone (HMAP) reduce cognitive dysfunction in vascular dementia during experimental diabetes. ( Sharma, B; Singh, N, 2010) |
| " Gene therapy strategies aimed at restoring cutaneous NO bioavailability may provide an effective means to ameliorate delayed diabetic wound healing." | 1.32 | Gene therapy of endothelial nitric oxide synthase and manganese superoxide dismutase restores delayed wound healing in type 1 diabetic mice. ( Chen, AF; Fu, WL; Luo, JD; Wang, YY; Wu, J, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (25.00) | 29.6817 |
| 2010's | 28 (70.00) | 24.3611 |
| 2020's | 2 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xianchu, L | 1 |
| Kang, L | 1 |
| Beiwan, D | 1 |
| Huan, P | 1 |
| Ming, L | 1 |
| Ding, W | 1 |
| Feng, H | 1 |
| Li, WJ | 1 |
| Liao, HH | 1 |
| Zhang, N | 1 |
| Zhou, ZY | 1 |
| Mou, SQ | 1 |
| Lin, Z | 1 |
| Xia-He, NZ | 1 |
| Xia, H | 1 |
| Tang, QZ | 1 |
| Qiu, J | 2 |
| Zhao, J | 2 |
| Li, J | 2 |
| Liang, X | 2 |
| Yang, Y | 2 |
| Zhang, Z | 2 |
| Zhang, X | 2 |
| Fu, H | 2 |
| Korantzopoulos, P | 2 |
| Tse, G | 1 |
| Liu, T | 2 |
| Li, G | 2 |
| Gimenes, R | 2 |
| Gimenes, C | 2 |
| Rosa, CM | 2 |
| Xavier, NP | 1 |
| Campos, DHS | 1 |
| Fernandes, AAH | 1 |
| Cezar, MDM | 1 |
| Guirado, GN | 2 |
| Pagan, LU | 1 |
| Chaer, ID | 1 |
| Fernandes, DC | 2 |
| Laurindo, FR | 2 |
| Cicogna, AC | 2 |
| Okoshi, MP | 2 |
| Okoshi, K | 2 |
| Cremonini, E | 1 |
| Oteiza, PI | 1 |
| Xin, R | 1 |
| Sun, X | 1 |
| Wang, Z | 2 |
| Yuan, W | 1 |
| Jiang, W | 1 |
| Wang, L | 1 |
| Xiang, Y | 1 |
| Zhang, H | 1 |
| Li, X | 1 |
| Hou, Y | 1 |
| Sun, W | 1 |
| Du, P | 1 |
| Wang, Y | 1 |
| Tao, J | 1 |
| Jiang, M | 1 |
| Yao, Y | 1 |
| Xue, H | 1 |
| Yuan, P | 1 |
| Ni, J | 1 |
| Li, C | 1 |
| Shao, D | 1 |
| Liu, J | 4 |
| Shen, Y | 1 |
| Zhou, L | 1 |
| Zhang, W | 2 |
| Huang, Y | 1 |
| Yu, C | 1 |
| Wang, R | 2 |
| Lu, L | 1 |
| Mohammad, G | 2 |
| Siddiquei, MM | 2 |
| Abu El-Asrar, AM | 2 |
| Winiarska, K | 3 |
| Focht, D | 2 |
| Sierakowski, B | 2 |
| Lewandowski, K | 1 |
| Orlowska, M | 1 |
| Usarek, M | 1 |
| Guo, F | 1 |
| Song, W | 1 |
| Jiang, T | 1 |
| Liu, L | 1 |
| Wang, F | 1 |
| Zhong, H | 1 |
| Yin, H | 1 |
| Wang, Q | 1 |
| Xiong, L | 1 |
| Lu, S | 1 |
| Xiang, L | 1 |
| Clemmer, JS | 1 |
| Mittwede, PN | 1 |
| Hester, RL | 1 |
| Ibrahim, AS | 1 |
| Tawfik, AM | 1 |
| Hussein, KA | 1 |
| Elshafey, S | 1 |
| Markand, S | 1 |
| Rizk, N | 1 |
| Duh, EJ | 1 |
| Smith, SB | 1 |
| Al-Shabrawey, M | 3 |
| Jarzyna, R | 1 |
| Dzik, JM | 1 |
| Jagielski, AK | 1 |
| Grabowski, M | 2 |
| Nowosielska, A | 1 |
| Alam, K | 1 |
| Nawaz, MI | 1 |
| Mousa, A | 1 |
| Campos, DH | 1 |
| Fernandes, AA | 1 |
| Queiroz, RM | 1 |
| Falcão-Pires, I | 1 |
| Miranda-Silva, D | 1 |
| Rodrigues, P | 1 |
| Correa, CR | 1 |
| Tawfik, A | 1 |
| Sanders, T | 2 |
| Kahook, K | 1 |
| Akeel, S | 1 |
| Elmarakby, A | 1 |
| Yang, XQ | 1 |
| Chen, AF | 2 |
| Rojas, M | 2 |
| Lilly, B | 1 |
| Tsai, NT | 1 |
| Lemtalsi, T | 1 |
| Liou, GI | 1 |
| Caldwell, RW | 1 |
| Caldwell, RB | 2 |
| Dhaunsi, GS | 1 |
| Yousif, MH | 1 |
| Akhtar, S | 1 |
| Chappell, MC | 1 |
| Diz, DI | 1 |
| Benter, IF | 1 |
| Thallas-Bonke, V | 2 |
| Coughlan, MT | 2 |
| Bach, LA | 2 |
| Cooper, ME | 2 |
| Forbes, JM | 2 |
| Sharma, B | 1 |
| Singh, N | 1 |
| Edlund, J | 1 |
| Fasching, A | 1 |
| Liss, P | 1 |
| Hansell, P | 2 |
| Palm, F | 2 |
| Rogacki, MK | 1 |
| Roe, ND | 1 |
| Thomas, DP | 1 |
| Ren, J | 1 |
| Oelze, M | 1 |
| Knorr, M | 1 |
| Schuhmacher, S | 1 |
| Heeren, T | 1 |
| Otto, C | 1 |
| Schulz, E | 1 |
| Reifenberg, K | 1 |
| Wenzel, P | 1 |
| Münzel, T | 1 |
| Daiber, A | 1 |
| Gao, S | 1 |
| Yuan, K | 1 |
| Shah, A | 1 |
| Kim, JS | 1 |
| Park, WH | 1 |
| Kim, SH | 1 |
| Serizawa, K | 1 |
| Yogo, K | 1 |
| Aizawa, K | 1 |
| Tashiro, Y | 1 |
| Ishizuka, N | 1 |
| Persson, P | 1 |
| Liu, Y | 1 |
| Qu, Y | 1 |
| Ma, Y | 1 |
| Xia, C | 1 |
| Gao, C | 1 |
| Lian, K | 1 |
| Xu, A | 1 |
| Lu, X | 1 |
| Sun, L | 1 |
| Yang, L | 1 |
| Lau, WB | 1 |
| Gao, E | 1 |
| Koch, W | 1 |
| Wang, H | 1 |
| Tao, L | 1 |
| Li, M | 2 |
| Liu, Z | 1 |
| Zhuan, L | 2 |
| Wang, T | 2 |
| Guo, S | 1 |
| Wang, S | 1 |
| Ye, Z | 2 |
| Rao, K | 1 |
| Yang, J | 2 |
| Quan, W | 1 |
| Cotter, MA | 1 |
| Cameron, NE | 1 |
| Luo, JD | 1 |
| Wang, YY | 1 |
| Fu, WL | 1 |
| Wu, J | 1 |
| Asaba, K | 1 |
| Tojo, A | 1 |
| Onozato, ML | 1 |
| Goto, A | 1 |
| Quinn, MT | 1 |
| Fujita, T | 1 |
| Wilcox, CS | 1 |
| Hayashi, T | 1 |
| Juliet, PA | 1 |
| Kano-Hayashi, H | 1 |
| Tsunekawa, T | 1 |
| Dingqunfang, D | 1 |
| Sumi, D | 1 |
| Matsui-Hirai, H | 1 |
| Fukatsu, A | 1 |
| Iguchi, A | 1 |
| Chen, P | 1 |
| Guo, AM | 1 |
| Edwards, PA | 1 |
| Trick, G | 1 |
| Scicli, AG | 1 |
| Thorpe, SR | 1 |
| Fukami, K | 1 |
| Yap, FY | 1 |
| Sourris, KC | 1 |
| Penfold, SA | 1 |
| Behzadian, A | 1 |
| El-Remessy, A | 1 |
| Bartoli, M | 1 |
| Parpia, AK | 1 |
| Liou, G | 1 |
40 other studies available for acetovanillone and Alloxan Diabetes
| Article | Year |
|---|---|
Apocynin ameliorates cognitive deficits in streptozotocin-induced diabetic rats.
Topics: Acetophenones; Animals; Cognition; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Hippocamp | 2021 |
Apocynin attenuates diabetic cardiomyopathy by suppressing ASK1-p38/JNK signaling.
Topics: Acetophenones; Animals; Animals, Newborn; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes | 2021 |
Apocynin attenuates left ventricular remodeling in diabetic rabbits.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Rabbits; Ventricular Rem | 2017 |
Influence of apocynin on cardiac remodeling in rats with streptozotocin-induced diabetes mellitus.
Topics: Acetophenones; Animals; Catalase; Collagen; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathi | 2018 |
(-)-Epicatechin and its metabolites prevent palmitate-induced NADPH oxidase upregulation, oxidative stress and insulin resistance in HepG2 cells.
Topics: Acetophenones; Animals; Benzoxazoles; Catechin; Diabetes Mellitus, Experimental; Diet, High-Fat; Enz | 2018 |
Apocynin inhibited NLRP3/XIAP signalling to alleviate renal fibrotic injury in rat diabetic nephropathy.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Antioxidants; Cytoprotection; Diabetes Mellitus, E | 2018 |
Apocynin ameliorates diabetic retinopathy in rats: Involvement of TLR4/NF-κB signaling pathway.
Topics: Acetophenones; Animals; Antioxidants; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Retinopat | 2019 |
H(2)S inhibits hyperglycemia-induced intrarenal renin-angiotensin system activation via attenuation of reactive oxygen species generation.
Topics: Acetophenones; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Blood Glucose; Cel | 2013 |
Poly (ADP-ribose) polymerase mediates diabetes-induced retinal neuropathy.
Topics: Acetophenones; Animals; Brain-Derived Neurotrophic Factor; Diabetes Mellitus, Experimental; Diabetic | 2013 |
NADPH oxidase inhibitor, apocynin, improves renal glutathione status in Zucker diabetic fatty rats: a comparison with melatonin.
Topics: Acetophenones; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Enzyme Inhibito | 2014 |
Electroacupuncture pretreatment inhibits NADPH oxidase-mediated oxidative stress in diabetic mice with cerebral ischemia.
Topics: Acetophenones; Animals; Brain; Brain Ischemia; Cinnamates; Diabetes Mellitus, Experimental; Electroa | 2014 |
Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 channels.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Boron Compounds; Capillary Permeabi | 2014 |
Pigment epithelium-derived factor inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Acetophenones; Animals; Arachidonate 12-Lipoxygenase; Ar | 2015 |
ERK1/2 pathway is involved in renal gluconeogenesis inhibition under conditions of lowered NADPH oxidase activity.
Topics: Acetophenones; Animals; Antioxidants; Butadienes; Cyclic AMP Response Element-Binding Protein; Cycli | 2015 |
Mutual enhancement between high-mobility group box-1 and NADPH oxidase-derived reactive oxygen species mediates diabetes-induced upregulation of retinal apoptotic markers.
Topics: Acetophenones; Animals; Apoptosis; Biomarkers; Caspase 3; Cells, Cultured; Diabetes Mellitus, Experi | 2015 |
NADPH oxidase inhibitor apocynin prevents atrial remodeling in alloxan-induced diabetic rabbits.
Topics: Acetophenones; Alloxan; Animals; Atrial Fibrillation; Atrial Remodeling; Diabetes Mellitus, Experime | 2016 |
Apocynin influence on oxidative stress and cardiac remodeling of spontaneously hypertensive rats with diabetes mellitus.
Topics: Acetophenones; Animals; Antioxidants; Catalase; Collagen Type III; Diabetes Mellitus, Experimental; | 2016 |
Suppression of retinal peroxisome proliferator-activated receptor gamma in experimental diabetes and oxygen-induced retinopathy: role of NADPH oxidase.
Topics: Acetophenones; Animals; Blotting, Western; Cell Culture Techniques; Diabetes Mellitus, Experimental; | 2009 |
High-cholesterol diet augments endothelial dysfunction via elevated oxidative stress and reduced tetrahydrobiopterin in Ins2(Akita) mice, an autosomal dominant mutant type 1 diabetic model.
Topics: Acetophenones; Animals; Biopterins; Cholesterol, Dietary; Diabetes Mellitus, Experimental; Diabetes | 2009 |
NAD(P)H oxidase-dependent regulation of CCL2 production during retinal inflammation.
Topics: Acetophenones; Animals; Blotting, Western; Cells, Cultured; Chemokine CCL2; Diabetes Mellitus, Exper | 2009 |
Angiotensin-(1-7) prevents diabetes-induced attenuation in PPAR-gamma and catalase activities.
Topics: Acetophenones; Angiotensin I; Animals; Antihypertensive Agents; Antioxidants; Blood Glucose; Blood P | 2010 |
Preservation of kidney function with combined inhibition of NADPH oxidase and angiotensin-converting enzyme in diabetic nephropathy.
Topics: Acetophenones; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Ex | 2010 |
Pitavastatin and 4'-hydroxy-3'-methoxyacetophenone (HMAP) reduce cognitive dysfunction in vascular dementia during experimental diabetes.
Topics: Acetophenones; Acetylcholinesterase; Animals; Blood Glucose; Brain; Cognition; Dementia, Vascular; D | 2010 |
The roles of NADPH-oxidase and nNOS for the increased oxidative stress and the oxygen consumption in the diabetic kidney.
Topics: Acetophenones; Animals; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney; | 2010 |
Inhibition of renal gluconeogenesis contributes to hypoglycaemic action of NADPH oxidase inhibitor, apocynin.
Topics: Acetophenones; Animals; Blood Glucose; Creatinine; Cyclic N-Oxides; Diabetes Mellitus, Experimental; | 2011 |
Inhibition of NADPH oxidase alleviates experimental diabetes-induced myocardial contractile dysfunction.
Topics: Acetophenones; Animals; Blotting, Western; Diabetes Mellitus, Experimental; Echocardiography; Enzyme | 2011 |
Vascular dysfunction in streptozotocin-induced experimental diabetes strictly depends on insulin deficiency.
Topics: Acetophenones; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endot | 2011 |
Suppression of high pacing-induced ANP secretion by antioxidants in isolated rat atria.
Topics: Acetophenones; Acetylcysteine; Animals; Antioxidants; Atrial Function; Atrial Natriuretic Factor; Bl | 2011 |
Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats.
Topics: Acetophenones; Animals; Antioxidants; Cells, Cultured; Cyclic N-Oxides; Diabetes Mellitus, Experimen | 2011 |
NADPH oxidase inhibition reduces tubular sodium transport and improves kidney oxygenation in diabetes.
Topics: Acetophenones; Animals; Biological Transport; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Gl | 2012 |
The alternative crosstalk between RAGE and nitrative thioredoxin inactivation during diabetic myocardial ischemia-reperfusion injury.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Free Radical Scavengers; | 2012 |
Effects of apocynin on oxidative stress and expression of apoptosis-related genes in testes of diabetic rats.
Topics: Acetophenones; Animals; Apoptosis; bcl-2-Associated X Protein; Diabetes Mellitus, Experimental; Gene | 2013 |
Apocynin improves erectile function in diabetic rats through regulation of NADPH oxidase expression.
Topics: Acetophenones; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Electric Stimulation; Enzym | 2012 |
Effect of the NAD(P)H oxidase inhibitor, apocynin, on peripheral nerve perfusion and function in diabetic rats.
Topics: Acetophenones; Administration, Oral; Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Ma | 2003 |
Gene therapy of endothelial nitric oxide synthase and manganese superoxide dismutase restores delayed wound healing in type 1 diabetic mice.
Topics: Acetophenones; Adenoviridae; Alkaloids; Animals; Benzophenanthridines; Biological Availability; Diab | 2004 |
Effects of NADPH oxidase inhibitor in diabetic nephropathy.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; | 2005 |
NADPH oxidase inhibitor, apocynin, restores the impaired endothelial-dependent and -independent responses and scavenges superoxide anion in rats with type 2 diabetes complicated by NO dysfunction.
Topics: Acetophenones; Animals; Antioxidants; Aorta; Arteriosclerosis; Diabetes Mellitus, Experimental; Diab | 2005 |
Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis.
Topics: Acetophenones; Acetylcysteine; Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Recept | 2007 |
Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; | 2008 |
Role of NADPH oxidase in retinal vascular inflammation.
Topics: Acetophenones; Animals; Blood-Retinal Barrier; Cell Adhesion; Diabetes Mellitus, Experimental; Diabe | 2008 |