acetovanillone has been researched along with Aging in 27 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nonalcoholic fatty liver disease (NAFLD) has been considered a novel component of the metabolic syndrome (MetS), with the oxidative stress participating in its progression." | 1.43 | Aging Increases Susceptibility to High Fat Diet-Induced Metabolic Syndrome in C57BL/6 Mice: Improvement in Glycemic and Lipid Profile after Antioxidant Therapy. ( César-Gomes, CJ; Da Fonseca, LJ; Guedes, Gda S; Nunes-Souza, V; Rabelo, LA; Smaniotto, S, 2016) |
| "However, whether AOPPs are involved in senile osteoporosis is still largely unknown." | 1.40 | Advanced oxidation protein products accelerate bone deterioration in aged rats. ( Chen, JT; Huang, ZP; Li, XD; Wu, Q; Wu, XH; Xie, F; Ye, WB; Zeng, JH; Zheng, S; Zhong, ZM; Zhou, J, 2014) |
| ": ED in middle-aged rats is associated with decreased NO bioavailability in erectile tissue due to upregulation of NADPH oxidase subunit gp91(phox) and downregulation of nNOS/p-eNOS." | 1.39 | Superoxide anion production by NADPH oxidase plays a major role in erectile dysfunction in middle-aged rats: prevention by antioxidant therapy. ( Antunes, E; Báu, FR; Brugnerotto, AF; Mónica, FZ; Priviero, FB; Silva, FH; Toque, HA, 2013) |
| " This study examined whether chronic intake of red wine polyphenols (RWPs), a rich source of natural antioxidants, prevents aging-related impairment of vascular function and physical exercise capacity." | 1.37 | Chronic intake of red wine polyphenols by young rats prevents aging-induced endothelial dysfunction and decline in physical performance: role of NADPH oxidase. ( Auger, C; Bronner, C; Dal-Ros, S; Geny, B; Keller, N; Lang, AL; Schini-Kerth, VB; Zoll, J, 2011) |
| "0%) mediated by reduced nitric oxide (NO) bioavailability (P < 0." | 1.37 | Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging. ( Calvert, JW; Fleenor, BS; Lefer, DJ; Marshall, KD; Seals, DR; Sindler, AL; Zigler, ML, 2011) |
| "Habitual aerobic exercise is associated with enhanced endothelium-dependent dilatation (EDD) in older humans, possibly by increasing nitric oxide bioavailability and reducing oxidative stress." | 1.35 | Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase. ( Connell, ML; Donato, AJ; Durrant, JR; Folian, BJ; Lawson, BR; Lesniewski, LA; Russell, MJ; Seals, DR, 2009) |
| "This study utilized middle cerebral artery occlusion (MCAO) with tissue plasminogen activator (tPA) to assess inhibition of the NOX2 isoform of NADPH oxidase on brain injury and functional recovery in aged rats." | 1.35 | NOX2 inhibition with apocynin worsens stroke outcome in aged rats. ( Huber, JD; Kelly, KA; Li, X; Rosen, CL; Tan, Z; VanGilder, RL, 2009) |
| " Superoxide anion (O(2)(-)) is a major determinant of nitric oxide (NO) bioavailability and thus endothelial function." | 1.31 | Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. ( Brosnan, MJ; Dominiczak, AF; Graham, D; Hamilton, CA; McIntyre, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (29.63) | 29.6817 |
| 2010's | 17 (62.96) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, F | 1 |
| Fan, LM | 1 |
| Michael, N | 1 |
| Li, JM | 1 |
| Shibuya, S | 1 |
| Watanabe, K | 1 |
| Ozawa, Y | 1 |
| Shimizu, T | 1 |
| Du, ZD | 1 |
| Yu, S | 1 |
| Qi, Y | 1 |
| Qu, TF | 1 |
| He, L | 1 |
| Wei, W | 1 |
| Liu, K | 1 |
| Gong, SS | 1 |
| Dayal, S | 1 |
| Wilson, KM | 1 |
| Motto, DG | 1 |
| Miller, FJ | 1 |
| Chauhan, AK | 1 |
| Lentz, SR | 1 |
| Zeng, JH | 1 |
| Zhong, ZM | 1 |
| Li, XD | 1 |
| Wu, Q | 1 |
| Zheng, S | 1 |
| Zhou, J | 1 |
| Ye, WB | 1 |
| Xie, F | 1 |
| Wu, XH | 1 |
| Huang, ZP | 1 |
| Chen, JT | 1 |
| De Pasquale, R | 1 |
| Beckhauser, TF | 1 |
| Hernandes, MS | 1 |
| Giorgetti Britto, LR | 1 |
| Han, BH | 1 |
| Zhou, ML | 1 |
| Johnson, AW | 1 |
| Singh, I | 1 |
| Liao, F | 1 |
| Vellimana, AK | 1 |
| Nelson, JW | 1 |
| Milner, E | 1 |
| Cirrito, JR | 1 |
| Basak, J | 1 |
| Yoo, M | 1 |
| Dietrich, HH | 1 |
| Holtzman, DM | 1 |
| Zipfel, GJ | 1 |
| Silva, E | 1 |
| Soares, AI | 1 |
| Costa, F | 1 |
| Castro, JP | 1 |
| Matos, L | 1 |
| Almeida, H | 1 |
| Sun, J | 1 |
| Ming, L | 1 |
| Shang, F | 1 |
| Shen, L | 1 |
| Chen, J | 1 |
| Jin, Y | 1 |
| Nunes-Souza, V | 1 |
| César-Gomes, CJ | 1 |
| Da Fonseca, LJ | 1 |
| Guedes, Gda S | 1 |
| Smaniotto, S | 1 |
| Rabelo, LA | 1 |
| Collins, AR | 1 |
| Lyon, CJ | 1 |
| Xia, X | 1 |
| Liu, JZ | 1 |
| Tangirala, RK | 1 |
| Yin, F | 1 |
| Boyadjian, R | 1 |
| Bikineyeva, A | 1 |
| Praticò, D | 1 |
| Harrison, DG | 1 |
| Hsueh, WA | 1 |
| Durrant, JR | 1 |
| Seals, DR | 2 |
| Connell, ML | 1 |
| Russell, MJ | 1 |
| Lawson, BR | 1 |
| Folian, BJ | 1 |
| Donato, AJ | 1 |
| Lesniewski, LA | 1 |
| Kelly, KA | 1 |
| Li, X | 1 |
| Tan, Z | 1 |
| VanGilder, RL | 1 |
| Rosen, CL | 1 |
| Huber, JD | 1 |
| Denvir, MA | 1 |
| Gray, GA | 1 |
| Miller, SJ | 2 |
| Coppinger, BJ | 1 |
| Zhou, X | 2 |
| Unthank, JL | 2 |
| Bohlen, HG | 1 |
| Bitar, MS | 1 |
| Ayed, AK | 1 |
| Abdel-Halim, SM | 1 |
| Isenovic, ER | 1 |
| Al-Mulla, F | 1 |
| Jeon, SM | 1 |
| Lee, SJ | 1 |
| Kwon, TK | 1 |
| Kim, KJ | 1 |
| Bae, YS | 1 |
| Sodero, AO | 1 |
| Weissmann, C | 1 |
| Ledesma, MD | 1 |
| Dotti, CG | 1 |
| Dal-Ros, S | 2 |
| Zoll, J | 1 |
| Lang, AL | 1 |
| Auger, C | 2 |
| Keller, N | 1 |
| Bronner, C | 2 |
| Geny, B | 1 |
| Schini-Kerth, VB | 2 |
| Sindler, AL | 1 |
| Fleenor, BS | 1 |
| Calvert, JW | 1 |
| Marshall, KD | 1 |
| Zigler, ML | 1 |
| Lefer, DJ | 1 |
| Drouin, A | 1 |
| Farhat, N | 1 |
| Bolduc, V | 1 |
| Thorin-Trescases, N | 1 |
| Gillis, MA | 1 |
| Villeneuve, L | 1 |
| Nguyen, A | 1 |
| Thorin, E | 1 |
| Silva, FH | 1 |
| Mónica, FZ | 1 |
| Báu, FR | 1 |
| Brugnerotto, AF | 1 |
| Priviero, FB | 1 |
| Toque, HA | 1 |
| Antunes, E | 1 |
| Adler, A | 1 |
| Messina, E | 1 |
| Sherman, B | 1 |
| Wang, Z | 1 |
| Huang, H | 1 |
| Linke, A | 1 |
| Hintze, TH | 1 |
| Jacobson, A | 1 |
| Yan, C | 1 |
| Gao, Q | 1 |
| Rincon-Skinner, T | 1 |
| Rivera, A | 1 |
| Edwards, J | 1 |
| Huang, A | 1 |
| Kaley, G | 1 |
| Sun, D | 1 |
| Hamilton, CA | 1 |
| Brosnan, MJ | 1 |
| McIntyre, M | 1 |
| Graham, D | 1 |
| Dominiczak, AF | 1 |
27 other studies available for acetovanillone and Aging
| Article | Year |
|---|---|
In vivo and in silico characterization of apocynin in reducing organ oxidative stress: A pharmacokinetic and pharmacodynamic study.
Topics: Acetophenones; Aging; Animals; Antioxidants; Blood-Brain Barrier; Computer Simulation; Diet, High-Fa | 2020 |
Xanthine Oxidoreductase-Mediated Superoxide Production Is Not Involved in the Age-Related Pathologies in
Topics: Acetophenones; Aging; Allopurinol; Anemia; Animals; Fatty Liver; Mice, Mutant Strains; Muscular Atro | 2021 |
NADPH oxidase inhibitor apocynin decreases mitochondrial dysfunction and apoptosis in the ventral cochlear nucleus of D-galactose-induced aging model in rats.
Topics: Acetophenones; Aging; Animals; Apoptosis; Cochlear Nucleus; Enzyme Inhibitors; Galactose; Male; Maze | 2019 |
Hydrogen peroxide promotes aging-related platelet hyperactivation and thrombosis.
Topics: Acetophenones; Aging; Animals; Blood Platelets; Catalase; Female; Glutathione Peroxidase; Glutathion | 2013 |
Advanced oxidation protein products accelerate bone deterioration in aged rats.
Topics: Acetophenones; Advanced Oxidation Protein Products; Aging; Animals; Antioxidants; Biomarkers; Biomec | 2014 |
LTP and LTD in the visual cortex require the activation of NOX2.
Topics: Acetophenones; Aging; Animals; Antioxidants; Dizocilpine Maleate; Enzyme Activation; Excitatory Amin | 2014 |
Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice.
Topics: Acetophenones; Aging; Animals; Apolipoproteins E; Astrocytes; Brain; Cerebral Amyloid Angiopathy; Ce | 2015 |
Antioxidant Supplementation Modulates Age-Related Placental Bed Morphology and Reproductive Outcome in Mice.
Topics: Acetophenones; Aging; Animals; Antioxidants; Cyclic N-Oxides; Decidua; Female; Fetus; Litter Size; M | 2015 |
Apocynin suppression of NADPH oxidase reverses the aging process in mesenchymal stem cells to promote osteogenesis and increase bone mass.
Topics: Acetophenones; Aging; Animals; Bone and Bones; Bone Density; Cell Differentiation; Humans; Mesenchym | 2015 |
Aging Increases Susceptibility to High Fat Diet-Induced Metabolic Syndrome in C57BL/6 Mice: Improvement in Glycemic and Lipid Profile after Antioxidant Therapy.
Topics: Acetophenones; Aging; Animals; Antioxidants; Blood Glucose; Catalase; Cyclic N-Oxides; Diet, High-Fa | 2016 |
Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes.
Topics: Acetophenones; Aging; Animals; Antioxidants; Atherosclerosis; Diabetes Mellitus; Diet, Atherogenic; | 2009 |
Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase.
Topics: Acetophenones; Acetylcholine; Aging; Animals; Carotid Arteries; Down-Regulation; Endothelium, Vascul | 2009 |
NOX2 inhibition with apocynin worsens stroke outcome in aged rats.
Topics: Acetophenones; Aging; Animals; Antioxidants; Blood-Brain Barrier; Brain; Capillary Permeability; Ede | 2009 |
Run for your life: exercise, oxidative stress and the ageing endothelium.
Topics: Acetophenones; Acetylcholine; Aging; Animals; Carotid Arteries; Down-Regulation; Endothelium, Vascul | 2009 |
Antioxidants reverse age-related collateral growth impairment.
Topics: Acetophenones; Age Factors; Aging; Animals; Antioxidants; Collateral Circulation; Cyclic N-Oxides; D | 2010 |
Abnormal nitric oxide production in aged rat mesenteric arteries is mediated by NAD(P)H oxidase-derived peroxide.
Topics: Acetophenones; Administration, Topical; Age Factors; Aging; Animals; Antioxidants; Catalase; Enzyme | 2009 |
Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism.
Topics: Acetophenones; Aging; Androstadienes; Animals; Antioxidants; Aorta; Apoptosis; Diabetes Mellitus, Ty | 2010 |
NADPH oxidase is involved in protein kinase CKII down-regulation-mediated senescence through elevation of the level of reactive oxygen species in human colon cancer cells.
Topics: Acetophenones; Acetylcysteine; Aging; Antioxidants; Casein Kinase II; Cellular Senescence; Colonic N | 2010 |
Cellular stress from excitatory neurotransmission contributes to cholesterol loss in hippocampal neurons aging in vitro.
Topics: Acetophenones; Aging; Animals; Apoptosis; Biotinylation; Cell Death; Cholesterol; Cholesterol 24-Hyd | 2011 |
Chronic intake of red wine polyphenols by young rats prevents aging-induced endothelial dysfunction and decline in physical performance: role of NADPH oxidase.
Topics: Acetophenones; Aging; Angiotensin II; Animals; Antioxidants; Arginase; Endothelium, Vascular; Enzyme | 2011 |
Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging.
Topics: Acetophenones; Acetylcholine; Administration, Oral; Aging; Animals; Biopterins; Carotid Arteries; Cy | 2011 |
Up-regulation of thromboxane A₂ impairs cerebrovascular eNOS function in aging atherosclerotic mice.
Topics: Acetophenones; Aging; Animals; Antioxidants; Atherosclerosis; Benzofurans; Catechin; Cerebral Arteri | 2011 |
Red wine polyphenols improve an established aging-related endothelial dysfunction in the mesenteric artery of middle-aged rats: role of oxidative stress.
Topics: Acetophenones; Aging; Animals; Antioxidants; Endothelium, Vascular; Mesenteric Arteries; NADPH Oxida | 2012 |
Superoxide anion production by NADPH oxidase plays a major role in erectile dysfunction in middle-aged rats: prevention by antioxidant therapy.
Topics: Acetophenones; Acetylcholine; Aging; Animals; Blood Pressure; Cyclic GMP; Down-Regulation; Electric | 2013 |
NAD(P)H oxidase-generated superoxide anion accounts for reduced control of myocardial O2 consumption by NO in old Fischer 344 rats.
Topics: Acetophenones; Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Body Weight; | 2003 |
Aging enhances pressure-induced arterial superoxide formation.
Topics: Acetophenones; Aging; Animals; Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Male; Mesen | 2007 |
Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction.
Topics: Acetophenones; Aging; Animals; Aorta; Blood Pressure; Carotid Arteries; Endothelium, Vascular; Enzym | 2001 |