acetone and Papilloma
acetone has been researched along with Papilloma in 29 studies
methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).
Papilloma: A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " It was found that induction of epidermal hyperplasia, with either a mixture of turpentine and acetone or phorbol esters, produced a marked increase in papilloma yield." | 3.69 | High efficiency induction of papillomas in vivo using recombinant cottontail rabbit papillomavirus DNA. ( Bower, JM; Christensen, ND; Cladel, NM; DiAngelo, SL; Kreider, JW; Patrick, SD; Welsh, PA, 1995) |
| "It is known that the free-radical-generating compound, benzoyl peroxide (BPO) enhances malignant conversion of murine skin benign papillomas into carcinomas." | 3.67 | Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds. ( Athar, M; Bickers, DR; Lloyd, JR; Mukhtar, H, 1989) |
| "Application of the alkane n-dodecane to the dorsal skin of 6-8 week old female SENCAR mice initiated with 10 nmol dimethylbenz[a]anthracene led to papilloma formation in the majority of treated animals." | 3.67 | Mechanism of mouse skin tumor promotion by n-dodecane. ( Baxter, CS; Miller, ML, 1987) |
| "Acetone treatment or chronic mechanical irritation did not cause LSC in the rats." | 1.46 | [Establishment of a SD rat model of vulvar lichen simplex chronicus and detection of the expression of protease activated receptor 2]. ( Fu, ZH; Li, CZ; Tang, HJ; Yang, H, 2017) |
| " Evidence of systemic toxicity was observed in animals dosed chronically with pyrimethamine or amiloride, but no skin papillomas were observed in mice treated with amiloride, dipyridamole, or pyrimethamine for 26 weeks." | 1.32 | Evaluation of the Tg.AC assay: specificity testing with three noncarcinogenic pharmaceuticals that induce selected stress gene promoters in vitro and the inhibitory effects of solvent components. ( Lin, KK; Rosenzweig, BA; Sistare, FD; Thompson, KL; Weaver, JL; Zhang, J, 2003) |
| "D/T/D/T mice developed squamous cell carcinomas (SCCs) 10 weeks earlier than D/T/A/T mice and demonstrated a 96% malignancy incidence and 1." | 1.30 | A multihit, multistage model of chemical carcinogenesis. ( Owens, DM; Smart, RC; Wei, S, 1999) |
| "In contrast, the incidence of squamous cell carcinomas (SCCs) (17-18/30 mice) did not increase with DMBA dose." | 1.29 | FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin. ( Glick, AB; Hennings, H; Krsmanovic, LS; Lowry, DT; Sly, LM; Yuspa, SH, 1993) |
| "Acetone-, TPA- or BaP-treated animals were used as negative and positive controls, respectively." | 1.28 | Comparative tumor-initiating ability of 7H-dibenzo(c,g)carbazole and dibenz(a,j)acridine in mouse skin. ( Andringa, A; Barkley, W; LaDow, K; Miller, ML; Warshawsky, D, 1992) |
| "GSHt contents in squamous cell carcinomas (SCC) were twice the values measured in papillomas and 5- to 8-fold greater than the values measured in non-treated skins, and the non-tumorous tissue adjacent to SCC." | 1.28 | Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part II: Quantitation of glutathione and glutathione disulfide. ( Cappel, RE; Gilbert, HF; Kodari, E; Reiners, JJ, 1991) |
| "The papillomas are heterogeneous in their potential for progression to carcinomas, a property apparently induced at the time of initiation." | 1.28 | Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin. ( Hennings, H, 1991) |
| " Additional dosing regimens were examined to determine whether the down-regulation of particulate PKC activity was associated with hyperplasia and tumor promotion." | 1.28 | Differential down-regulation of epidermal protein kinase C by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol: association with epidermal hyperplasia and tumor promotion. ( Hansen, LA; Monteiro-Riviere, NA; Smart, RC, 1990) |
| " There existed an excellent dose-response relationship for SC from type 308 Cytrel tested at four dose levels: 8." | 1.26 | Mouse skin assay of condensate from smoking products other than tobacco. ( Bernfeld, P; Homburger, F, 1976) |
Research
Studies (29)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (58.62) | 18.7374 |
| 1990's | 10 (34.48) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 1 (3.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Yang, H | 1 |
| Fu, ZH | 1 |
| Tang, HJ | 1 |
| Li, CZ | 1 |
| Thompson, KL | 1 |
| Rosenzweig, BA | 1 |
| Weaver, JL | 1 |
| Zhang, J | 1 |
| Lin, KK | 1 |
| Sistare, FD | 1 |
| HOMBURGER, F | 2 |
| TREGER, A | 1 |
| BAKER, JR | 1 |
| ROE, FJ | 2 |
| CLACK, J | 1 |
| Sundberg, JP | 1 |
| Erickson, AA | 1 |
| Roop, DR | 1 |
| Binder, RL | 1 |
| Hennings, H | 2 |
| Glick, AB | 1 |
| Lowry, DT | 1 |
| Krsmanovic, LS | 1 |
| Sly, LM | 1 |
| Yuspa, SH | 1 |
| Kreider, JW | 1 |
| Cladel, NM | 1 |
| Patrick, SD | 1 |
| Welsh, PA | 1 |
| DiAngelo, SL | 1 |
| Bower, JM | 1 |
| Christensen, ND | 1 |
| Owens, DM | 1 |
| Wei, S | 1 |
| Smart, RC | 2 |
| Slaga, TJ | 1 |
| Viaje, A | 1 |
| Bracken, WM | 1 |
| Berry, DL | 1 |
| Fischer, SM | 1 |
| Miller, DR | 1 |
| Leclerc, SM | 1 |
| Ziegler, MM | 1 |
| Lopez, V | 1 |
| Barker, CF | 1 |
| Bernfeld, P | 1 |
| Nelson, MA | 1 |
| Futscher, BW | 1 |
| Kinsella, T | 1 |
| Wymer, J | 1 |
| Bowden, GT | 2 |
| Warshawsky, D | 1 |
| Barkley, W | 1 |
| Miller, ML | 2 |
| LaDow, K | 1 |
| Andringa, A | 1 |
| Reiners, JJ | 1 |
| Kodari, E | 1 |
| Cappel, RE | 1 |
| Gilbert, HF | 1 |
| Iversen, OH | 1 |
| Hansen, LA | 1 |
| Monteiro-Riviere, NA | 1 |
| Athar, M | 1 |
| Lloyd, JR | 1 |
| Bickers, DR | 1 |
| Mukhtar, H | 1 |
| Robinson, M | 1 |
| Bull, RJ | 1 |
| Olson, GR | 1 |
| Stober, J | 1 |
| Chu, KC | 1 |
| Brown, CC | 1 |
| Tarone, RE | 1 |
| Tan, WY | 1 |
| Jaffe, DR | 1 |
| Williamson, JF | 1 |
| Baxter, CS | 1 |
| Takigawa, M | 1 |
| Simsiman, RC | 1 |
| Boutwell, RK | 1 |
| Rohrbach, R | 1 |
| King, ME | 1 |
| Shefner, AM | 1 |
| Bates, RR | 1 |
| Carter, RL | 1 |
| Mitchley, BC | 1 |
| Peto, R | 1 |
| Hecker, E | 1 |
| Yasuhira, K | 1 |
| Gosh, TE | 1 |
| Nevskaia, EA | 1 |
| Khar'kovskaia, NA | 1 |
| Searle, CE | 1 |
Other Studies
29 other studies available for acetone and Papilloma
| Article | Year |
|---|---|
[Establishment of a SD rat model of vulvar lichen simplex chronicus and detection of the expression of protease activated receptor 2].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; Disease Models, Animal; Female; Fri | 2017 |
Evaluation of the Tg.AC assay: specificity testing with three noncarcinogenic pharmaceuticals that induce selected stress gene promoters in vitro and the inhibitory effects of solvent components.
Topics: Acetone; Administration, Topical; Amiloride; Animal Testing Alternatives; Animals; Carcinogenicity T | 2003 |
MOUSE-SKIN PAINTING WITH SMOKE CONDENSATES FROM CIGARETTES MADE OF PIPE, CIGAR, AND CIGARETTE TOBACCOS.
Topics: Acetone; Animals; Benzopyrenes; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Hyperplasia; Hyper | 1963 |
TWO-STAGE CARCINOGENESIS: EFFECT OF LENGTH AND PROMOTING TREATMENT ON THE YIELD OF BENIGN AND MALIGNANT TUMOURS.
Topics: Acetone; Animals; Benzopyrenes; Carcinogenesis; Carcinogens; Croton Oil; Mice; Neoplasm Metastasis; | 1963 |
Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Cell Differentiation; Female; Filaggrin Proteins | 1994 |
FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Cell; Drug Resistance; Femal | 1993 |
High efficiency induction of papillomas in vivo using recombinant cottontail rabbit papillomavirus DNA.
Topics: Acetone; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cottontail rabbit pap | 1995 |
A multihit, multistage model of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Tran | 1999 |
Skin-tumor-initiating ability of benzo(a)pyrene-7,8-diol-9,10-epoxide (anti) when applied topically in tetrahydrofuran.
Topics: Acetone; Animals; Benzene; Benzopyrenes; Carcinogens; Drug Interactions; Female; Furans; Mice; Neopl | 1977 |
Carcinogenesis in an immunologically privileged site.
Topics: Acetone; Administration, Topical; Animals; Cheek; Cricetinae; Disease Models, Animal; Drug Implants; | 1975 |
Mouse skin assay of condensate from smoking products other than tobacco.
Topics: Acetone; Animals; Body Weight; Carcinoma; Dose-Response Relationship, Drug; Female; Mice; Neoplasms, | 1976 |
Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Base Sequence; Carcinoma, Squamous Cell; DNA, Ne | 1992 |
Comparative tumor-initiating ability of 7H-dibenzo(c,g)carbazole and dibenz(a,j)acridine in mouse skin.
Topics: Acetone; Acridines; Animals; Benzo(a)pyrene; Carbazoles; Carcinogens; Female; Mice; Papilloma; Skin; | 1992 |
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part II: Quantitation of glutathione and glutathione disulfide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Topical; Aging; Animals; Carcinoma, Squam | 1991 |
Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Ce | 1991 |
The skin tumorigenic and carcinogenic effects of different doses, numbers of dose fractions and concentrations of 7,12-dimethylbenz[a]anthracene in acetone applied on hairless mouse epidermis. Possible implications for human carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Cutaneous; Animals; Carcinoma; Dose-Respo | 1991 |
Differential down-regulation of epidermal protein kinase C by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol: association with epidermal hyperplasia and tumor promotion.
Topics: Acetone; Animals; Diglycerides; Down-Regulation; Female; Glycerides; Hyperplasia; Mice; Papilloma; P | 1990 |
Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Amidines; Animals; Benzoyl Peroxide; Carcinogens; Cell Tr | 1989 |
Carcinogenic activity associated with halogenated acetones and acroleins in the mouse skin assay.
Topics: Acetone; Acrolein; Aldehydes; Animals; Carcinogenicity Tests; Female; Mice; Papilloma; Skin Neoplasm | 1989 |
Differentiating among proposed mechanisms for tumor promotion in mouse skin with the use of the multievent model for cancer.
Topics: 4-Nitroquinoline-1-oxide; Acetone; Animals; Cell Transformation, Neoplastic; Mathematics; Mice; Mode | 1987 |
Ionizing radiation enhances malignant progression of mouse skin tumors.
Topics: Acetone; Animals; Carcinoma; Cocarcinogenesis; Female; Methylnitronitrosoguanidine; Mice; Neoplasms, | 1987 |
Mechanism of mouse skin tumor promotion by n-dodecane.
Topics: Acetone; Alkanes; Animals; Cocarcinogenesis; Diterpenes; Female; Mice; Papilloma; Skin Neoplasms; Te | 1987 |
Tumor promoter-induced refractory state against ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate in mouse epidermis.
Topics: Acetone; Alkynes; Animals; Carcinogens; Cycloheximide; Diterpenes; Dose-Response Relationship, Drug; | 1986 |
[The stimulation of dopaoxidase-positive melanocytes during skin carcinogenesis].
Topics: Acetone; Animals; Benz(a)Anthracenes; Carcinoma; Croton Oil; Histological Techniques; Hyperplasia; K | 1969 |
Carcinogenesis bioassay of chlorinated dibenzodioxins and related chemicals.
Topics: Acetone; Administration, Oral; Animals; Benz(a)Anthracenes; Body Weight; Carcinoma, Squamous Cell; C | 1973 |
On the persistence of tumour initiation and the acceleration of tumour progression in mouse skin tumorigenesis.
Topics: Acetone; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Croton Oil; Female; Mice; Neo | 1972 |
Induction of malignant lymphoma and other tumors during experiments with anthralin painting of mice.
Topics: Acetone; Adenoma; Animals; Anthracenes; Carcinoma; Injections, Intraperitoneal; Lung Neoplasms; Lymp | 1968 |
[Features of the development and course of cancer of the uterine cervix in mice of various lines].
Topics: Acetone; Animals; Benzopyrenes; Carcinoma, Squamous Cell; Cell Nucleus; Female; Mice; Papilloma; Pre | 1969 |
Tumor initiatory activity of some chloromononitrobenzenes and other compounds.
Topics: Acetone; Animals; Croton Oil; Ethylmaleimide; Female; Male; Mice; Neoplasms, Experimental; Nitrobenz | 1966 |