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acetone and Papilloma

acetone has been researched along with Papilloma in 29 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

Papilloma: A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
" It was found that induction of epidermal hyperplasia, with either a mixture of turpentine and acetone or phorbol esters, produced a marked increase in papilloma yield."3.69High efficiency induction of papillomas in vivo using recombinant cottontail rabbit papillomavirus DNA. ( Bower, JM; Christensen, ND; Cladel, NM; DiAngelo, SL; Kreider, JW; Patrick, SD; Welsh, PA, 1995)
"It is known that the free-radical-generating compound, benzoyl peroxide (BPO) enhances malignant conversion of murine skin benign papillomas into carcinomas."3.67Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds. ( Athar, M; Bickers, DR; Lloyd, JR; Mukhtar, H, 1989)
"Application of the alkane n-dodecane to the dorsal skin of 6-8 week old female SENCAR mice initiated with 10 nmol dimethylbenz[a]anthracene led to papilloma formation in the majority of treated animals."3.67Mechanism of mouse skin tumor promotion by n-dodecane. ( Baxter, CS; Miller, ML, 1987)
"Acetone treatment or chronic mechanical irritation did not cause LSC in the rats."1.46[Establishment of a SD rat model of vulvar lichen simplex chronicus and detection of the expression of protease activated receptor 2]. ( Fu, ZH; Li, CZ; Tang, HJ; Yang, H, 2017)
" Evidence of systemic toxicity was observed in animals dosed chronically with pyrimethamine or amiloride, but no skin papillomas were observed in mice treated with amiloride, dipyridamole, or pyrimethamine for 26 weeks."1.32Evaluation of the Tg.AC assay: specificity testing with three noncarcinogenic pharmaceuticals that induce selected stress gene promoters in vitro and the inhibitory effects of solvent components. ( Lin, KK; Rosenzweig, BA; Sistare, FD; Thompson, KL; Weaver, JL; Zhang, J, 2003)
"D/T/D/T mice developed squamous cell carcinomas (SCCs) 10 weeks earlier than D/T/A/T mice and demonstrated a 96% malignancy incidence and 1."1.30A multihit, multistage model of chemical carcinogenesis. ( Owens, DM; Smart, RC; Wei, S, 1999)
"In contrast, the incidence of squamous cell carcinomas (SCCs) (17-18/30 mice) did not increase with DMBA dose."1.29FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin. ( Glick, AB; Hennings, H; Krsmanovic, LS; Lowry, DT; Sly, LM; Yuspa, SH, 1993)
"Acetone-, TPA- or BaP-treated animals were used as negative and positive controls, respectively."1.28Comparative tumor-initiating ability of 7H-dibenzo(c,g)carbazole and dibenz(a,j)acridine in mouse skin. ( Andringa, A; Barkley, W; LaDow, K; Miller, ML; Warshawsky, D, 1992)
"GSHt contents in squamous cell carcinomas (SCC) were twice the values measured in papillomas and 5- to 8-fold greater than the values measured in non-treated skins, and the non-tumorous tissue adjacent to SCC."1.28Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part II: Quantitation of glutathione and glutathione disulfide. ( Cappel, RE; Gilbert, HF; Kodari, E; Reiners, JJ, 1991)
"The papillomas are heterogeneous in their potential for progression to carcinomas, a property apparently induced at the time of initiation."1.28Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin. ( Hennings, H, 1991)
" Additional dosing regimens were examined to determine whether the down-regulation of particulate PKC activity was associated with hyperplasia and tumor promotion."1.28Differential down-regulation of epidermal protein kinase C by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol: association with epidermal hyperplasia and tumor promotion. ( Hansen, LA; Monteiro-Riviere, NA; Smart, RC, 1990)
" There existed an excellent dose-response relationship for SC from type 308 Cytrel tested at four dose levels: 8."1.26Mouse skin assay of condensate from smoking products other than tobacco. ( Bernfeld, P; Homburger, F, 1976)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199017 (58.62)18.7374
1990's10 (34.48)18.2507
2000's1 (3.45)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, H1
Fu, ZH1
Tang, HJ1
Li, CZ1
Thompson, KL1
Rosenzweig, BA1
Weaver, JL1
Zhang, J1
Lin, KK1
Sistare, FD1
HOMBURGER, F2
TREGER, A1
BAKER, JR1
ROE, FJ2
CLACK, J1
Sundberg, JP1
Erickson, AA1
Roop, DR1
Binder, RL1
Hennings, H2
Glick, AB1
Lowry, DT1
Krsmanovic, LS1
Sly, LM1
Yuspa, SH1
Kreider, JW1
Cladel, NM1
Patrick, SD1
Welsh, PA1
DiAngelo, SL1
Bower, JM1
Christensen, ND1
Owens, DM1
Wei, S1
Smart, RC2
Slaga, TJ1
Viaje, A1
Bracken, WM1
Berry, DL1
Fischer, SM1
Miller, DR1
Leclerc, SM1
Ziegler, MM1
Lopez, V1
Barker, CF1
Bernfeld, P1
Nelson, MA1
Futscher, BW1
Kinsella, T1
Wymer, J1
Bowden, GT2
Warshawsky, D1
Barkley, W1
Miller, ML2
LaDow, K1
Andringa, A1
Reiners, JJ1
Kodari, E1
Cappel, RE1
Gilbert, HF1
Iversen, OH1
Hansen, LA1
Monteiro-Riviere, NA1
Athar, M1
Lloyd, JR1
Bickers, DR1
Mukhtar, H1
Robinson, M1
Bull, RJ1
Olson, GR1
Stober, J1
Chu, KC1
Brown, CC1
Tarone, RE1
Tan, WY1
Jaffe, DR1
Williamson, JF1
Baxter, CS1
Takigawa, M1
Simsiman, RC1
Boutwell, RK1
Rohrbach, R1
King, ME1
Shefner, AM1
Bates, RR1
Carter, RL1
Mitchley, BC1
Peto, R1
Hecker, E1
Yasuhira, K1
Gosh, TE1
Nevskaia, EA1
Khar'kovskaia, NA1
Searle, CE1

Other Studies

29 other studies available for acetone and Papilloma

ArticleYear
[Establishment of a SD rat model of vulvar lichen simplex chronicus and detection of the expression of protease activated receptor 2].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2017, Jan-20, Volume: 37, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; Disease Models, Animal; Female; Fri

2017
Evaluation of the Tg.AC assay: specificity testing with three noncarcinogenic pharmaceuticals that induce selected stress gene promoters in vitro and the inhibitory effects of solvent components.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 74, Issue:2

    Topics: Acetone; Administration, Topical; Amiloride; Animal Testing Alternatives; Animals; Carcinogenicity T

2003
MOUSE-SKIN PAINTING WITH SMOKE CONDENSATES FROM CIGARETTES MADE OF PIPE, CIGAR, AND CIGARETTE TOBACCOS.
    Journal of the National Cancer Institute, 1963, Volume: 31

    Topics: Acetone; Animals; Benzopyrenes; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Hyperplasia; Hyper

1963
TWO-STAGE CARCINOGENESIS: EFFECT OF LENGTH AND PROMOTING TREATMENT ON THE YIELD OF BENIGN AND MALIGNANT TUMOURS.
    British journal of cancer, 1963, Volume: 17

    Topics: Acetone; Animals; Benzopyrenes; Carcinogenesis; Carcinogens; Croton Oil; Mice; Neoplasm Metastasis;

1963
Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10.
    Cancer research, 1994, Mar-01, Volume: 54, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Cell Differentiation; Female; Filaggrin Proteins

1994
FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin.
    Carcinogenesis, 1993, Volume: 14, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Cell; Drug Resistance; Femal

1993
High efficiency induction of papillomas in vivo using recombinant cottontail rabbit papillomavirus DNA.
    Journal of virological methods, 1995, Volume: 55, Issue:2

    Topics: Acetone; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cottontail rabbit pap

1995
A multihit, multistage model of chemical carcinogenesis.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Tran

1999
Skin-tumor-initiating ability of benzo(a)pyrene-7,8-diol-9,10-epoxide (anti) when applied topically in tetrahydrofuran.
    Cancer letters, 1977, Volume: 3, Issue:1-2

    Topics: Acetone; Animals; Benzene; Benzopyrenes; Carcinogens; Drug Interactions; Female; Furans; Mice; Neopl

1977
Carcinogenesis in an immunologically privileged site.
    The Journal of surgical research, 1975, Volume: 18, Issue:2

    Topics: Acetone; Administration, Topical; Animals; Cheek; Cricetinae; Disease Models, Animal; Drug Implants;

1975
Mouse skin assay of condensate from smoking products other than tobacco.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:4

    Topics: Acetone; Animals; Body Weight; Carcinoma; Dose-Response Relationship, Drug; Female; Mice; Neoplasms,

1976
Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Jul-15, Volume: 89, Issue:14

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Base Sequence; Carcinoma, Squamous Cell; DNA, Ne

1992
Comparative tumor-initiating ability of 7H-dibenzo(c,g)carbazole and dibenz(a,j)acridine in mouse skin.
    Toxicology, 1992, Volume: 71, Issue:3

    Topics: Acetone; Acridines; Animals; Benzo(a)pyrene; Carbazoles; Carcinogens; Female; Mice; Papilloma; Skin;

1992
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part II: Quantitation of glutathione and glutathione disulfide.
    Carcinogenesis, 1991, Volume: 12, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Topical; Aging; Animals; Carcinoma, Squam

1991
Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin.
    Basic life sciences, 1991, Volume: 57

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Ce

1991
The skin tumorigenic and carcinogenic effects of different doses, numbers of dose fractions and concentrations of 7,12-dimethylbenz[a]anthracene in acetone applied on hairless mouse epidermis. Possible implications for human carcinogenesis.
    Carcinogenesis, 1991, Volume: 12, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Cutaneous; Animals; Carcinoma; Dose-Respo

1991
Differential down-regulation of epidermal protein kinase C by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol: association with epidermal hyperplasia and tumor promotion.
    Cancer research, 1990, Sep-15, Volume: 50, Issue:18

    Topics: Acetone; Animals; Diglycerides; Down-Regulation; Female; Glycerides; Hyperplasia; Mice; Papilloma; P

1990
Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds.
    Carcinogenesis, 1989, Volume: 10, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Amidines; Animals; Benzoyl Peroxide; Carcinogens; Cell Tr

1989
Carcinogenic activity associated with halogenated acetones and acroleins in the mouse skin assay.
    Cancer letters, 1989, Volume: 48, Issue:3

    Topics: Acetone; Acrolein; Aldehydes; Animals; Carcinogenicity Tests; Female; Mice; Papilloma; Skin Neoplasm

1989
Differentiating among proposed mechanisms for tumor promotion in mouse skin with the use of the multievent model for cancer.
    Journal of the National Cancer Institute, 1987, Volume: 79, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Acetone; Animals; Cell Transformation, Neoplastic; Mathematics; Mice; Mode

1987
Ionizing radiation enhances malignant progression of mouse skin tumors.
    Carcinogenesis, 1987, Volume: 8, Issue:11

    Topics: Acetone; Animals; Carcinoma; Cocarcinogenesis; Female; Methylnitronitrosoguanidine; Mice; Neoplasms,

1987
Mechanism of mouse skin tumor promotion by n-dodecane.
    Carcinogenesis, 1987, Volume: 8, Issue:12

    Topics: Acetone; Alkanes; Animals; Cocarcinogenesis; Diterpenes; Female; Mice; Papilloma; Skin Neoplasms; Te

1987
Tumor promoter-induced refractory state against ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate in mouse epidermis.
    Cancer research, 1986, Volume: 46, Issue:1

    Topics: Acetone; Alkynes; Animals; Carcinogens; Cycloheximide; Diterpenes; Dose-Response Relationship, Drug;

1986
[The stimulation of dopaoxidase-positive melanocytes during skin carcinogenesis].
    Virchows Archiv. B, Cell pathology, 1969, Volume: 3, Issue:2

    Topics: Acetone; Animals; Benz(a)Anthracenes; Carcinoma; Croton Oil; Histological Techniques; Hyperplasia; K

1969
Carcinogenesis bioassay of chlorinated dibenzodioxins and related chemicals.
    Environmental health perspectives, 1973, Volume: 5

    Topics: Acetone; Administration, Oral; Animals; Benz(a)Anthracenes; Body Weight; Carcinoma, Squamous Cell; C

1973
On the persistence of tumour initiation and the acceleration of tumour progression in mouse skin tumorigenesis.
    International journal of cancer, 1972, Mar-15, Volume: 9, Issue:2

    Topics: Acetone; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Croton Oil; Female; Mice; Neo

1972
Induction of malignant lymphoma and other tumors during experiments with anthralin painting of mice.
    Gan, 1968, Volume: 59, Issue:3

    Topics: Acetone; Adenoma; Animals; Anthracenes; Carcinoma; Injections, Intraperitoneal; Lung Neoplasms; Lymp

1968
[Features of the development and course of cancer of the uterine cervix in mice of various lines].
    Voprosy onkologii, 1969, Volume: 15, Issue:1

    Topics: Acetone; Animals; Benzopyrenes; Carcinoma, Squamous Cell; Cell Nucleus; Female; Mice; Papilloma; Pre

1969
Tumor initiatory activity of some chloromononitrobenzenes and other compounds.
    Cancer research, 1966, Volume: 26, Issue:1

    Topics: Acetone; Animals; Croton Oil; Ethylmaleimide; Female; Male; Mice; Neoplasms, Experimental; Nitrobenz

1966