acetone and Pain
acetone has been researched along with Pain in 9 studies
methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pain has become an active clinical challenge due its etiological heterogeneity, symptoms and mechanisms of action." | 1.43 | Antinociceptive effects of a new sigma-1 receptor antagonist (N-(2-morpholin-4-yl-ethyl)-2-(1-naphthyloxy)acetamide) in two types of nociception. ( Domínguez-Ramírez, AM; Espinosa-Juárez, JV; García-Martínez, BA; Jaramillo-Morales, OA; López-Muñoz, FJ; Medina-López, JR; Melo-Hernández, LA; Navarrete-Vázquez, G; Schepmann, D; Wünsch, B, 2016) |
| "Chronic itch (pruritus) is an important clinical problem." | 1.43 | Enhanced itch elicited by capsaicin in a chronic itch model. ( Chen, M; Gegen, T; Guo, CJ; He, Q; Hu, D; Li, F; Liu, Q; Shi, H; Tang, M; Tang, Z; Wang, C; Wang, Z; Yang, N; Yang, Y; Yu, G; Zhu, C, 2016) |
| "The animals develop heat-hyperalgesia, mechano-hyperalgesia, mechano-allodynia, and cold-allodynia that last for several days." | 1.33 | Characterization of a model of cutaneous inflammatory pain produced by an ultraviolet irradiation-evoked sterile injury in the rat. ( Bennett, GJ; Davies, SL; Siau, C, 2005) |
Research
Studies (9)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Cao, LF | 1 |
| Si, M | 1 |
| Huang, Y | 1 |
| Chen, LH | 1 |
| Peng, XY | 1 |
| Qin, YQ | 1 |
| Liu, TT | 1 |
| Zhou, Y | 1 |
| Liu, T | 1 |
| Luo, WF | 1 |
| García-Martínez, BA | 1 |
| Jaramillo-Morales, OA | 1 |
| Espinosa-Juárez, JV | 1 |
| Navarrete-Vázquez, G | 1 |
| Melo-Hernández, LA | 1 |
| Medina-López, JR | 1 |
| Domínguez-Ramírez, AM | 1 |
| Schepmann, D | 1 |
| Wünsch, B | 1 |
| López-Muñoz, FJ | 1 |
| Yu, G | 1 |
| Yang, N | 1 |
| Li, F | 1 |
| Chen, M | 1 |
| Guo, CJ | 1 |
| Wang, C | 1 |
| Hu, D | 1 |
| Yang, Y | 1 |
| Zhu, C | 1 |
| Wang, Z | 1 |
| Shi, H | 1 |
| Gegen, T | 1 |
| Tang, M | 1 |
| He, Q | 1 |
| Liu, Q | 1 |
| Tang, Z | 1 |
| Davies, SL | 1 |
| Siau, C | 1 |
| Bennett, GJ | 1 |
| Park, HJ | 1 |
| Lee, Y | 1 |
| Lee, J | 1 |
| Park, C | 1 |
| Moon, DE | 1 |
| Chapman, V | 1 |
| Suzuki, R | 1 |
| Dickenson, AH | 1 |
| Dringenberg, HC | 1 |
| Saber, AJ | 1 |
| Cahill, L | 1 |
| Al-Yousuf, MH | 1 |
| Bashir, AK | 1 |
| Ali, BH | 1 |
| Tanira, MO | 1 |
| Blunden, G | 1 |
| Naumann, HN | 1 |
| Diggs, LW | 1 |
| Schlenker, FS | 1 |
| Barreras, L | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intraoral Administration of Onabotulinum Toxin A for Continuous Neuropathic Pain: a Single Subject Experimental Design[NCT03848143] | Phase 2 | 10 participants (Anticipated) | Interventional | 2019-09-11 | Recruiting | ||
| Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy[NCT03571334] | Phase 2 | 40 participants (Anticipated) | Interventional | 2020-07-08 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Other Studies
9 other studies available for acetone and Pain
| Article | Year |
|---|---|
Long-term anti-itch effect of botulinum neurotoxin A is associated with downregulation of TRPV1 and TRPA1 in the dorsal root ganglia in mice.
Topics: Acetone; Animals; Botulinum Toxins, Type A; Chloroquine; Chronic Disease; Disease Models, Animal; Do | 2017 |
Antinociceptive effects of a new sigma-1 receptor antagonist (N-(2-morpholin-4-yl-ethyl)-2-(1-naphthyloxy)acetamide) in two types of nociception.
Topics: Acetamides; Acetone; Analgesics; Analgesics, Opioid; Animals; Arthritis; Constriction, Pathologic; D | 2016 |
Enhanced itch elicited by capsaicin in a chronic itch model.
Topics: Acetone; Animals; Behavior, Animal; Capsaicin; Chronic Disease; Disease Models, Animal; Ether; Femal | 2016 |
Characterization of a model of cutaneous inflammatory pain produced by an ultraviolet irradiation-evoked sterile injury in the rat.
Topics: Acetone; Animals; Cold Temperature; Disease Models, Animal; Hyperalgesia; Inflammation; Male; Nocice | 2005 |
The effects of botulinum toxin A on mechanical and cold allodynia in a rat model of neuropathic pain.
Topics: Acetone; Analgesics; Animals; Botulinum Toxins, Type A; Cold Temperature; Foot; Hindlimb; Ligation; | 2006 |
The effects of botulinum toxin A on mechanical and cold allodynia in a rat model of neuropathic pain.
Topics: Acetone; Analgesics; Animals; Botulinum Toxins, Type A; Cold Temperature; Foot; Hindlimb; Ligation; | 2006 |
The effects of botulinum toxin A on mechanical and cold allodynia in a rat model of neuropathic pain.
Topics: Acetone; Analgesics; Animals; Botulinum Toxins, Type A; Cold Temperature; Foot; Hindlimb; Ligation; | 2006 |
The effects of botulinum toxin A on mechanical and cold allodynia in a rat model of neuropathic pain.
Topics: Acetone; Analgesics; Animals; Botulinum Toxins, Type A; Cold Temperature; Foot; Hindlimb; Ligation; | 2006 |
Electrophysiological characterization of spinal neuronal response properties in anaesthetized rats after ligation of spinal nerves L5-L6.
Topics: Acetone; Anesthesia, General; Animals; Denervation; Electrophysiology; Functional Laterality; Hindli | 1998 |
Enhanced frontal cortex activation in rats by convergent amygdaloid and noxious sensory signals.
Topics: Acetone; Amygdala; Animals; Electroencephalography; Fear; Frontal Lobe; Male; Neurons, Afferent; Pai | 2001 |
Some effects of Salvia aegyptiaca L. on the central nervous system in mice.
Topics: Acetone; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Body Temperature; Central Nerv | 2002 |
Increased urinary porphyrin excretion in sickle cell crises.
Topics: Acetone; Adolescent; Adult; Anemia, Sickle Cell; Child; Female; Fever; Humans; Levulinic Acids; Male | 1966 |