Page last updated: 2024-10-16

acetone and Pain

acetone has been researched along with Pain in 9 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Pain has become an active clinical challenge due its etiological heterogeneity, symptoms and mechanisms of action."1.43Antinociceptive effects of a new sigma-1 receptor antagonist (N-(2-morpholin-4-yl-ethyl)-2-(1-naphthyloxy)acetamide) in two types of nociception. ( Domínguez-Ramírez, AM; Espinosa-Juárez, JV; García-Martínez, BA; Jaramillo-Morales, OA; López-Muñoz, FJ; Medina-López, JR; Melo-Hernández, LA; Navarrete-Vázquez, G; Schepmann, D; Wünsch, B, 2016)
"Chronic itch (pruritus) is an important clinical problem."1.43Enhanced itch elicited by capsaicin in a chronic itch model. ( Chen, M; Gegen, T; Guo, CJ; He, Q; Hu, D; Li, F; Liu, Q; Shi, H; Tang, M; Tang, Z; Wang, C; Wang, Z; Yang, N; Yang, Y; Yu, G; Zhu, C, 2016)
"The animals develop heat-hyperalgesia, mechano-hyperalgesia, mechano-allodynia, and cold-allodynia that last for several days."1.33Characterization of a model of cutaneous inflammatory pain produced by an ultraviolet irradiation-evoked sterile injury in the rat. ( Bennett, GJ; Davies, SL; Siau, C, 2005)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cao, LF1
Si, M1
Huang, Y1
Chen, LH1
Peng, XY1
Qin, YQ1
Liu, TT1
Zhou, Y1
Liu, T1
Luo, WF1
García-Martínez, BA1
Jaramillo-Morales, OA1
Espinosa-Juárez, JV1
Navarrete-Vázquez, G1
Melo-Hernández, LA1
Medina-López, JR1
Domínguez-Ramírez, AM1
Schepmann, D1
Wünsch, B1
López-Muñoz, FJ1
Yu, G1
Yang, N1
Li, F1
Chen, M1
Guo, CJ1
Wang, C1
Hu, D1
Yang, Y1
Zhu, C1
Wang, Z1
Shi, H1
Gegen, T1
Tang, M1
He, Q1
Liu, Q1
Tang, Z1
Davies, SL1
Siau, C1
Bennett, GJ1
Park, HJ1
Lee, Y1
Lee, J1
Park, C1
Moon, DE1
Chapman, V1
Suzuki, R1
Dickenson, AH1
Dringenberg, HC1
Saber, AJ1
Cahill, L1
Al-Yousuf, MH1
Bashir, AK1
Ali, BH1
Tanira, MO1
Blunden, G1
Naumann, HN1
Diggs, LW1
Schlenker, FS1
Barreras, L1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intraoral Administration of Onabotulinum Toxin A for Continuous Neuropathic Pain: a Single Subject Experimental Design[NCT03848143]Phase 210 participants (Anticipated)Interventional2019-09-11Recruiting
Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy[NCT03571334]Phase 240 participants (Anticipated)Interventional2020-07-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for acetone and Pain

ArticleYear
Long-term anti-itch effect of botulinum neurotoxin A is associated with downregulation of TRPV1 and TRPA1 in the dorsal root ganglia in mice.
    Neuroreport, 2017, Jun-14, Volume: 28, Issue:9

    Topics: Acetone; Animals; Botulinum Toxins, Type A; Chloroquine; Chronic Disease; Disease Models, Animal; Do

2017
Antinociceptive effects of a new sigma-1 receptor antagonist (N-(2-morpholin-4-yl-ethyl)-2-(1-naphthyloxy)acetamide) in two types of nociception.
    European journal of pharmacology, 2016, Jan-15, Volume: 771

    Topics: Acetamides; Acetone; Analgesics; Analgesics, Opioid; Animals; Arthritis; Constriction, Pathologic; D

2016
Enhanced itch elicited by capsaicin in a chronic itch model.
    Molecular pain, 2016, Volume: 12

    Topics: Acetone; Animals; Behavior, Animal; Capsaicin; Chronic Disease; Disease Models, Animal; Ether; Femal

2016
Characterization of a model of cutaneous inflammatory pain produced by an ultraviolet irradiation-evoked sterile injury in the rat.
    Journal of neuroscience methods, 2005, Oct-30, Volume: 148, Issue:2

    Topics: Acetone; Animals; Cold Temperature; Disease Models, Animal; Hyperalgesia; Inflammation; Male; Nocice

2005
The effects of botulinum toxin A on mechanical and cold allodynia in a rat model of neuropathic pain.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:5

    Topics: Acetone; Analgesics; Animals; Botulinum Toxins, Type A; Cold Temperature; Foot; Hindlimb; Ligation;

2006
The effects of botulinum toxin A on mechanical and cold allodynia in a rat model of neuropathic pain.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:5

    Topics: Acetone; Analgesics; Animals; Botulinum Toxins, Type A; Cold Temperature; Foot; Hindlimb; Ligation;

2006
The effects of botulinum toxin A on mechanical and cold allodynia in a rat model of neuropathic pain.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:5

    Topics: Acetone; Analgesics; Animals; Botulinum Toxins, Type A; Cold Temperature; Foot; Hindlimb; Ligation;

2006
The effects of botulinum toxin A on mechanical and cold allodynia in a rat model of neuropathic pain.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:5

    Topics: Acetone; Analgesics; Animals; Botulinum Toxins, Type A; Cold Temperature; Foot; Hindlimb; Ligation;

2006
Electrophysiological characterization of spinal neuronal response properties in anaesthetized rats after ligation of spinal nerves L5-L6.
    The Journal of physiology, 1998, Mar-15, Volume: 507 ( Pt 3)

    Topics: Acetone; Anesthesia, General; Animals; Denervation; Electrophysiology; Functional Laterality; Hindli

1998
Enhanced frontal cortex activation in rats by convergent amygdaloid and noxious sensory signals.
    Neuroreport, 2001, Aug-08, Volume: 12, Issue:11

    Topics: Acetone; Amygdala; Animals; Electroencephalography; Fear; Frontal Lobe; Male; Neurons, Afferent; Pai

2001
Some effects of Salvia aegyptiaca L. on the central nervous system in mice.
    Journal of ethnopharmacology, 2002, Volume: 81, Issue:1

    Topics: Acetone; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Body Temperature; Central Nerv

2002
Increased urinary porphyrin excretion in sickle cell crises.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 123, Issue:1

    Topics: Acetone; Adolescent; Adult; Anemia, Sickle Cell; Child; Female; Fever; Humans; Levulinic Acids; Male

1966