acetone has been researched along with Disease Models, Animal in 60 studies
methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The von Frey filaments, acetone drop, and radiant heat test were performed to assess the degree of mechanical allodynia, thermal allodynia and thermal hyperalgesia respectively, at different time intervals, i." | 7.78 | Evaluation of aqueous and ethanolic extracts of saffron, Crocus sativus L., and its constituents, safranal and crocin in allodynia and hyperalgesia induced by chronic constriction injury model of neuropathic pain in rats. ( Amin, B; Hosseinzadeh, H, 2012) |
| "The acetone soluble fraction from a crude methanol extract of Stryphnodendron adstringens stem bark (AFSAB) was evaluated in acute (ethanol, indomethacin and hypothermic restraint-stress) and chronic (acetic acid) models of gastric ulceration and on basal and bethanechol-stimulated gastric acid secretion in rats." | 7.71 | The acetone soluble fraction from bark extract of Stryphnodendron adstringens (Mart.) coville inhibits gastric acid secretion and experimental gastric ulceration in rats. ( Lima, JC; Martins, DT; Rao, VS, 2002) |
| "We investigated the effects of AH-9700 (1-[2-(3,4-dihydro-6,7-dimethyl-2-naphthalenyl)ethyl] pyrrolidine fumarate; a novel sigma receptor ligand), (+)-pentazocine and 1,3-di-o-tolylguanidine (DTG) (two typical sigma receptor ligands), and oxybutynin (a currently used anti-pollakiuria drug) on cystometrograms in anesthetized rats with 30% acetone-induced cystitis." | 7.71 | Effects of AH-9700, (+)-pentazocine, DTG and oxybutynin on micturition in anesthetized rats with acetone-induced cystitis. ( Ishii, D; Kawashima, K; Oka, M; Shimizu, I, 2001) |
| "Cystitis was induced by i." | 5.36 | Comparison of voiding function and nociceptive behavior in two rat models of cystitis induced by cyclophosphamide or acetone. ( Chancellor, MB; de Groat, WC; Saitoh, C; Yokoyama, H; Yoshimura, N, 2010) |
| "Acetone is considered to be a substance that can disturb cellular oxidative status, being also associated with the production of glucose during its metabolization." | 5.36 | Chronic acetonemia alters liver oxidative balance and lipid content in rats. A model of NASH? ( de Almeida, BB; Jordao, AA; Mathias, MG; Portari, GV, 2010) |
| " We characterised the effect of contact dermatitis on the skin microbiota and studied the biological effects of oxazolone (OXA) -induced inflammation on skin thickness, immune cell numbers and changes of the microbiota in CHS mouse model (n = 72) for 28 days." | 4.12 | Skin microbiota of oxazolone-induced contact hypersensitivity mouse model. ( Alenius, H; El-Nezami, H; Ilves, M; Karisola, P; Mäenpää, K; Sinkko, H; Wang, S, 2022) |
| " (Cucurbitaceae) is one of the most valued plant species to treat cardiovascular diseases, including hypertension." | 3.88 | Acetone fraction from Sechium edule (Jacq.) S.w. edible roots exhibits anti-endothelial dysfunction activity. ( Arrellín, G; Barrita-Cruz, GJ; Castro-Martínez, G; Fragoso, G; Hernández, B; Jiménez-Ferrer, JE; Lombardo-Earl, G; Medina-Campos, ON; Méndez-Martínez, M; Pedraza-Chaverri, J; Ramírez, CC; Rosas, G; Santana, MA; Trejo-Moreno, C; Zamilpa, A, 2018) |
| " An acetone-ether-water (AEW) model as a histamine-independent itch model is often used in the study of chronic pruritus." | 3.85 | MrgprA3 shows sensitization to chloroquine in an acetone-ether-water mice model. ( Geng, X; Gu, L; Hu, D; Lan, L; Shi, H; Tang, Z; Wang, C; Wu, G; Yang, N; Yang, Y; Yu, G; Yu, L; Yuan, X; Zhu, C, 2017) |
| "In the present study the acetone extract of Ficus amplissima leaves were studied for enzymatic antioxidant activity through different assays, anti-inflammatory by using carrageenan and histamine induced rat paw edema models (50mg, 100mg acetone extract) and wound healing activity by incorporating the two doses (1% (w/w) and 2% (w/w)) of acetone extract and simple ointment base B." | 3.79 | Anti-inflammatory, wound healing and in-vivo antioxidant properties of the leaves of Ficus amplissima Smith. ( Arunachalam, K; Parimelazhagan, T, 2013) |
| " The von Frey filaments, acetone drop, and radiant heat test were performed to assess the degree of mechanical allodynia, thermal allodynia and thermal hyperalgesia respectively, at different time intervals, i." | 3.78 | Evaluation of aqueous and ethanolic extracts of saffron, Crocus sativus L., and its constituents, safranal and crocin in allodynia and hyperalgesia induced by chronic constriction injury model of neuropathic pain in rats. ( Amin, B; Hosseinzadeh, H, 2012) |
| "To develop a behavioral model in mice that is capable of mimicking some distinctive symptoms of human posttraumatic trigeminal neuropathic pain such as spontaneous pain, cold allodynia, and chemical÷inflammatory hyperalgesia, and to use this model to investigate the antinociceptive effects of clomipramine and tramadol, two drugs used for the treatment of neuropathic pain." | 3.77 | Antihyperalgesic effects of clomipramine and tramadol in a model of posttraumatic trigeminal neuropathic pain in mice. ( Alvarez, P; Brun, A; Constandil, L; Correa, A; Hernández, A; Labertrandie, A; Lopez, J; Pelissier, T, 2011) |
| "Acetone is the principal ketone body elevated in the ketogenic diet (KD), with demonstrated robust anticonvulsant properties across a variety of seizure tests and models of epilepsy." | 3.75 | Pharmacodynamic and pharmacokinetic interactions between common antiepileptic drugs and acetone, the chief anticonvulsant ketone body elevated in the ketogenic diet in mice. ( Buszewicz, G; Czuczwar, SJ; Gasior, M; Luszczki, JJ; Madro, R; Zarnowska, I; Zarnowski, T, 2009) |
| "As a model of dry skin pruritus in mice, one hind paw was treated twice daily with a mixture of acetone/diethylether/water (AEW); controls received water only." | 3.72 | Spinal c-fos expression associated with spontaneous biting in a mouse model of dry skin pruritus. ( Carstens, E; Carstens, MI; Cuellar, JM; Nojima, H; Simons, CT, 2004) |
| "The acetone soluble fraction from a crude methanol extract of Stryphnodendron adstringens stem bark (AFSAB) was evaluated in acute (ethanol, indomethacin and hypothermic restraint-stress) and chronic (acetic acid) models of gastric ulceration and on basal and bethanechol-stimulated gastric acid secretion in rats." | 3.71 | The acetone soluble fraction from bark extract of Stryphnodendron adstringens (Mart.) coville inhibits gastric acid secretion and experimental gastric ulceration in rats. ( Lima, JC; Martins, DT; Rao, VS, 2002) |
| "We investigated the effects of AH-9700 (1-[2-(3,4-dihydro-6,7-dimethyl-2-naphthalenyl)ethyl] pyrrolidine fumarate; a novel sigma receptor ligand), (+)-pentazocine and 1,3-di-o-tolylguanidine (DTG) (two typical sigma receptor ligands), and oxybutynin (a currently used anti-pollakiuria drug) on cystometrograms in anesthetized rats with 30% acetone-induced cystitis." | 3.71 | Effects of AH-9700, (+)-pentazocine, DTG and oxybutynin on micturition in anesthetized rats with acetone-induced cystitis. ( Ishii, D; Kawashima, K; Oka, M; Shimizu, I, 2001) |
| "Irritable bladder syndrome (IBS) was induced in four female African green monkeys (Cercopithecus aethiops) by the use of intravesical instillation of acetone." | 3.69 | Irritable bladder syndrome in an animal model: a continuous monitoring study. ( Clarke, MR; Ghoniem, GM; Shaaban, AM, 1995) |
| " Peak edema occurred 24-48 h after NM administration using optimized dosing methods and volume." | 1.91 | Depilatory double-disc mouse model for evaluation of vesicant dermal injury pharmacotherapy countermeasures. ( Gao, D; Laskin, JD; Li, S; Roldan, TL; Sinko, PJ, 2023) |
| "Acetone-treated animals had reduced weight gain during treatment despite comparable food consumption to non-treated mice, suggesting transient effects on nutrient uptake." | 1.62 | Acetone Ingestion Mimics a Fasting State to Improve Glucose Tolerance in a Mouse Model of Gestational Hyperglycemia. ( Arany, E; Bennett, J; Deane, M; Hill, DJ; Strutt, B; Szlapinski, S, 2021) |
| "Acetone treatment or chronic mechanical irritation did not cause LSC in the rats." | 1.46 | [Establishment of a SD rat model of vulvar lichen simplex chronicus and detection of the expression of protease activated receptor 2]. ( Fu, ZH; Li, CZ; Tang, HJ; Yang, H, 2017) |
| "Chronic itch (pruritus) is an important clinical problem." | 1.43 | Enhanced itch elicited by capsaicin in a chronic itch model. ( Chen, M; Gegen, T; Guo, CJ; He, Q; Hu, D; Li, F; Liu, Q; Shi, H; Tang, M; Tang, Z; Wang, C; Wang, Z; Yang, N; Yang, Y; Yu, G; Zhu, C, 2016) |
| " In an acute toxicity study, the extract at a dose of 2 g kg(-1) did not cause any adverse changes and no mortality was observed." | 1.38 | Cardioprotective activity of standardized extract of Ficus racemosa stem bark against doxorubicin-induced toxicity. ( Ahmed, F; Urooj, A, 2012) |
| "Cystitis was induced by i." | 1.36 | Comparison of voiding function and nociceptive behavior in two rat models of cystitis induced by cyclophosphamide or acetone. ( Chancellor, MB; de Groat, WC; Saitoh, C; Yokoyama, H; Yoshimura, N, 2010) |
| " Hence, GPs hold promising potential for increasing drug targetability vis a vis reducing dosing frequency with the interception of minimal side effects, for efficient management of tuberculosis." | 1.36 | Gelatin nanocarriers as potential vectors for effective management of tuberculosis. ( Agrawal, GP; Gupta, P; Gupta, UD; Jain, NK; Saraogi, GK, 2010) |
| "Acetone is considered to be a substance that can disturb cellular oxidative status, being also associated with the production of glucose during its metabolization." | 1.36 | Chronic acetonemia alters liver oxidative balance and lipid content in rats. A model of NASH? ( de Almeida, BB; Jordao, AA; Mathias, MG; Portari, GV, 2010) |
| "The animals develop heat-hyperalgesia, mechano-hyperalgesia, mechano-allodynia, and cold-allodynia that last for several days." | 1.33 | Characterization of a model of cutaneous inflammatory pain produced by an ultraviolet irradiation-evoked sterile injury in the rat. ( Bennett, GJ; Davies, SL; Siau, C, 2005) |
| "Acetone has been shown to have broad-spectrum anticonvulsant actions in animal seizure models and has been hypothesized to play a role in the anticonvulsant mechanism of the ketogenic diet (KD)." | 1.33 | A ketogenic diet and diallyl sulfide do not elevate afterdischarge thresholds in adult kindled rats. ( Burnham, WM; Hum, KM; Likhodii, SS; Nylen, K, 2006) |
| "It concerns the Wistar-derived rat with contact hypersensitivity (CHS), also a T cell mediated disorder that has already been studied extensively in several other fields of research." | 1.28 | An animal model for extracorporeal photochemotherapy based on contact hypersensitivity. ( Beijersbergen van Henegouwen, GM; van Iperen, HP, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (16.67) | 18.7374 |
| 1990's | 6 (10.00) | 18.2507 |
| 2000's | 14 (23.33) | 29.6817 |
| 2010's | 25 (41.67) | 24.3611 |
| 2020's | 5 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Szlapinski, S | 1 |
| Strutt, B | 1 |
| Deane, M | 1 |
| Arany, E | 1 |
| Bennett, J | 1 |
| Hill, DJ | 1 |
| Mäenpää, K | 1 |
| Wang, S | 1 |
| Ilves, M | 1 |
| El-Nezami, H | 1 |
| Alenius, H | 1 |
| Sinkko, H | 1 |
| Karisola, P | 1 |
| Zemelka-Wiacek, M | 1 |
| Majewska-Szczepanik, M | 1 |
| Gajdanowicz, P | 1 |
| Szczepanik, M | 1 |
| Roldan, TL | 1 |
| Li, S | 1 |
| Laskin, JD | 1 |
| Gao, D | 1 |
| Sinko, PJ | 1 |
| Sun, C | 1 |
| Li, Z | 1 |
| Ma, C | 1 |
| Zang, Q | 1 |
| Li, J | 1 |
| Liu, W | 1 |
| Zhao, H | 1 |
| Wang, X | 1 |
| Millecamps, M | 1 |
| Shi, XQ | 1 |
| Piltonen, M | 1 |
| Echeverry, S | 1 |
| Diatchenko, L | 1 |
| Zhang, J | 1 |
| Stone, LS | 1 |
| Cao, LF | 1 |
| Si, M | 1 |
| Huang, Y | 1 |
| Chen, LH | 1 |
| Peng, XY | 1 |
| Qin, YQ | 1 |
| Liu, TT | 1 |
| Zhou, Y | 1 |
| Liu, T | 1 |
| Luo, WF | 1 |
| Shi, H | 2 |
| Yu, G | 2 |
| Geng, X | 1 |
| Gu, L | 1 |
| Yang, N | 2 |
| Wang, C | 2 |
| Zhu, C | 2 |
| Yang, Y | 2 |
| Yu, L | 1 |
| Hu, D | 2 |
| Yuan, X | 1 |
| Lan, L | 1 |
| Wu, G | 1 |
| Tang, Z | 2 |
| Trejo-Moreno, C | 1 |
| Castro-Martínez, G | 1 |
| Méndez-Martínez, M | 1 |
| Jiménez-Ferrer, JE | 1 |
| Pedraza-Chaverri, J | 1 |
| Arrellín, G | 1 |
| Zamilpa, A | 1 |
| Medina-Campos, ON | 1 |
| Lombardo-Earl, G | 1 |
| Barrita-Cruz, GJ | 1 |
| Hernández, B | 1 |
| Ramírez, CC | 1 |
| Santana, MA | 1 |
| Fragoso, G | 1 |
| Rosas, G | 1 |
| Zhao, X | 1 |
| Yu, C | 1 |
| Ye, F | 1 |
| Wang, YG | 1 |
| Mei, QY | 1 |
| Ma, Q | 1 |
| Cui, WG | 1 |
| Zhou, WH | 1 |
| Iwanaga, T | 1 |
| Tominaga, M | 2 |
| Hirata, Y | 1 |
| Matsuda, H | 1 |
| Shimanuki, T | 1 |
| Ogawa, H | 3 |
| Takamori, K | 2 |
| Fan, Y | 1 |
| Tang, H | 1 |
| Liu, Y | 1 |
| Li, C | 1 |
| Al-Massri, KF | 1 |
| Ahmed, LA | 1 |
| El-Abhar, HS | 1 |
| Kamo, A | 1 |
| Taneda, K | 1 |
| Patel, R | 1 |
| Rutten, K | 1 |
| Valdor, M | 1 |
| Schiene, K | 1 |
| Wigge, S | 1 |
| Schunk, S | 1 |
| Damann, N | 1 |
| Christoph, T | 1 |
| Dickenson, AH | 1 |
| Schüttenhelm, BN | 1 |
| Duraku, LS | 1 |
| Dijkstra, JF | 1 |
| Walbeehm, ET | 1 |
| Holstege, JC | 1 |
| Barcelos, RC | 1 |
| de Mello-Sampayo, C | 1 |
| Antoniazzi, CT | 1 |
| Segat, HJ | 1 |
| Silva, H | 1 |
| Veit, JC | 1 |
| Piccolo, J | 1 |
| Emanuelli, T | 1 |
| Bürger, ME | 1 |
| Silva-Lima, B | 1 |
| Rodrigues, LM | 1 |
| Li, F | 1 |
| Chen, M | 1 |
| Guo, CJ | 1 |
| Wang, Z | 1 |
| Gegen, T | 1 |
| Tang, M | 1 |
| He, Q | 1 |
| Liu, Q | 1 |
| Yang, H | 1 |
| Fu, ZH | 1 |
| Tang, HJ | 1 |
| Li, CZ | 1 |
| Zarnowska, I | 1 |
| Luszczki, JJ | 1 |
| Zarnowski, T | 1 |
| Buszewicz, G | 1 |
| Madro, R | 1 |
| Czuczwar, SJ | 1 |
| Gasior, M | 3 |
| Saitoh, C | 1 |
| Yokoyama, H | 1 |
| Chancellor, MB | 1 |
| de Groat, WC | 1 |
| Yoshimura, N | 1 |
| Kim, SH | 1 |
| Yang, SO | 1 |
| Kim, HS | 1 |
| Kim, Y | 1 |
| Park, T | 1 |
| Choi, HK | 1 |
| Saraogi, GK | 1 |
| Gupta, P | 1 |
| Gupta, UD | 1 |
| Jain, NK | 1 |
| Agrawal, GP | 1 |
| de Almeida, BB | 1 |
| Mathias, MG | 1 |
| Portari, GV | 1 |
| Jordao, AA | 1 |
| Datta, S | 1 |
| Chatterjee, K | 1 |
| Kline, RH | 1 |
| Wiley, RG | 1 |
| Hasebe, N | 1 |
| Abe, K | 1 |
| Sugiyama, E | 1 |
| Hosoi, R | 1 |
| Inoue, O | 1 |
| Lomash, V | 1 |
| Deb, U | 1 |
| Rai, R | 1 |
| Jadhav, SE | 1 |
| Vijayaraghavan, R | 1 |
| Pant, SC | 1 |
| Akiyama, T | 1 |
| Carstens, MI | 2 |
| Carstens, E | 2 |
| Ahmed, F | 1 |
| Urooj, A | 1 |
| Alvarez, P | 1 |
| Brun, A | 1 |
| Labertrandie, A | 1 |
| Lopez, J | 1 |
| Correa, A | 1 |
| Constandil, L | 1 |
| Hernández, A | 1 |
| Pelissier, T | 1 |
| Amin, B | 1 |
| Hosseinzadeh, H | 1 |
| Arunachalam, K | 1 |
| Parimelazhagan, T | 1 |
| Martins, DT | 1 |
| Lima, JC | 1 |
| Rao, VS | 1 |
| Nojima, H | 1 |
| Cuellar, JM | 1 |
| Simons, CT | 1 |
| Sy, GY | 1 |
| Cissé, A | 1 |
| Nongonierma, RB | 1 |
| Sarr, M | 1 |
| Mbodj, NA | 1 |
| Faye, B | 1 |
| Davies, SL | 1 |
| Siau, C | 1 |
| Bennett, GJ | 1 |
| Nylen, K | 1 |
| Likhodii, SS | 1 |
| Hum, KM | 1 |
| Burnham, WM | 1 |
| Urano, K | 1 |
| Suzuki, S | 1 |
| Machida, K | 1 |
| Sawa, N | 1 |
| Eguchi, N | 1 |
| Kikuchi, K | 1 |
| Fukasawa, K | 1 |
| Taguchi, F | 1 |
| Usui, T | 1 |
| French, A | 1 |
| Joy, MT | 1 |
| Tang, RS | 1 |
| Hartman, AL | 2 |
| Rogawski, MA | 2 |
| Kalapos, MP | 1 |
| Pauluhn, J | 1 |
| Eveson, JW | 1 |
| MacDonald, DG | 1 |
| Buehler, EV | 1 |
| Ghoniem, GM | 1 |
| Shaaban, AM | 1 |
| Clarke, MR | 1 |
| Mortz, CG | 1 |
| Andersen, KE | 1 |
| Halkier-Sørensen, L | 1 |
| Katoh, N | 1 |
| Hirano, S | 1 |
| Kishimoto, S | 1 |
| Yasuno, H | 1 |
| Sjögren, F | 1 |
| Groth, O | 1 |
| Anderson, C | 1 |
| Shimizu, I | 1 |
| Kawashima, K | 1 |
| Ishii, D | 1 |
| Oka, M | 1 |
| Unno, T | 1 |
| Suto, H | 1 |
| Yoshiike, T | 1 |
| Ra, C | 1 |
| Ziegler, MM | 1 |
| Lopez, V | 1 |
| Barker, CF | 1 |
| van Iperen, HP | 1 |
| Beijersbergen van Henegouwen, GM | 1 |
| Sinclair, PR | 1 |
| Bement, WJ | 1 |
| Lambrecht, RW | 1 |
| Jacobs, JM | 1 |
| Sinclair, JF | 1 |
| Schlecht, S | 1 |
| Lester, D | 2 |
| Freed, EX | 2 |
| Sakazaki, R | 1 |
| Tamura, K | 1 |
| Nakamura, A | 1 |
| Kurata, T | 1 |
| Goda, A | 1 |
| Johnson, JA | 1 |
| Czaplewski, RR | 1 |
| Fusaro, RM | 1 |
| Yamaguchi, H | 1 |
| Fujii, J | 1 |
| Kurihara, H | 1 |
| Ikeda, M | 1 |
| Nakao, K | 1 |
| Zierott, G | 1 |
| Meyer, C | 1 |
| Lundsgaard-Hansen, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Skin Barrier Dysfunction and the Role of Skin Barrier Restoration on Cutaneous and Systemic Inflammation in the Aged Population[NCT03728569] | Early Phase 1 | 14 participants (Actual) | Interventional | 2018-05-16 | Terminated (stopped due to Enrollment and interactions/interventions paused due to COVID-19. Not expected to resume in the future. This is not a suspension of IRB approval) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
60 other studies available for acetone and Disease Models, Animal
| Article | Year |
|---|---|
Acetone Ingestion Mimics a Fasting State to Improve Glucose Tolerance in a Mouse Model of Gestational Hyperglycemia.
Topics: Acetone; Animals; Antimalarials; Apelin; Artesunate; Diabetes, Gestational; Disease Models, Animal; | 2021 |
Skin microbiota of oxazolone-induced contact hypersensitivity mouse model.
Topics: Acetone; Animals; Bacteria; Dermatitis, Allergic Contact; Disease Models, Animal; Inflammation; Mice | 2022 |
Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis.
Topics: Acetone; Animals; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; Ethanol; Haptens; | 2022 |
Depilatory double-disc mouse model for evaluation of vesicant dermal injury pharmacotherapy countermeasures.
Topics: Acetone; Acetylcholinesterase; Animals; Disease Models, Animal; Female; Irritants; Male; Mechloretha | 2023 |
Acetone immersion enhanced MALDI-MS imaging of small molecule metabolites in biological tissues.
Topics: Acetone; Animals; Disease Models, Animal; Fatty Acid Synthase, Type I; Glutaminase; Histocytological | 2019 |
The geriatric pain experience in mice: intact cutaneous thresholds but altered responses to tonic and chronic pain.
Topics: Acetone; Aging; Animals; Behavior; Biogenic Monoamines; Capsaicin; Chronic Pain; Disease Models, Ani | 2020 |
Long-term anti-itch effect of botulinum neurotoxin A is associated with downregulation of TRPV1 and TRPA1 in the dorsal root ganglia in mice.
Topics: Acetone; Animals; Botulinum Toxins, Type A; Chloroquine; Chronic Disease; Disease Models, Animal; Do | 2017 |
MrgprA3 shows sensitization to chloroquine in an acetone-ether-water mice model.
Topics: Acetone; Animals; Calcium; Cations, Divalent; Cells, Cultured; Chloroquine; Chronic Disease; Disease | 2017 |
Acetone fraction from Sechium edule (Jacq.) S.w. edible roots exhibits anti-endothelial dysfunction activity.
Topics: Acetone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Cinnamates; | 2018 |
Chronic itch impairs mood and HPA axis function in mice: modulation by CRFR1 antagonist.
Topics: Acetone; Adaptation, Ocular; Animals; Disease Models, Animal; Diterpenes; Feeding Behavior; Fever; F | 2018 |
Effects of Film Dressings on Itch Hypersensitivity Using Murine Dry Skin Models.
Topics: Acetone; Animals; Bandages; Dermatitis, Atopic; Disease Models, Animal; Epidermis; Ether; Male; Mice | 2018 |
[Establishment of a rat model of dimethylbenzanthracene-induced vulvar squamous intraepithelial lesions].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Blotting, Western; Carcinogens; Disease Models, | 2018 |
Mesenchymal stem cells therapy enhances the efficacy of pregabalin and prevents its motor impairment in paclitaxel-induced neuropathy in rats: Role of Notch1 receptor and JAK/STAT signaling pathway.
Topics: Acetone; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Caspase 3; | 2019 |
Neurotropin inhibits the increase in intraepidermal nerve density in the acetone-treated dry-skin mouse model.
Topics: Acetone; Animals; Disease Models, Animal; Epidermis; Male; Mice; Mice, Inbred ICR; Nerve Growth Fact | 2013 |
Electrophysiological characterization of activation state-dependent Ca(v)2 channel antagonist TROX-1 in spinal nerve injured rats.
Topics: Acetone; Action Potentials; Animals; Calcium Channel Blockers; Disease Models, Animal; Dose-Response | 2015 |
Differential Changes in the Peptidergic and the Non-Peptidergic Skin Innervation in Rat Models for Inflammation, Dry Skin Itch, and Dermatitis.
Topics: Acetone; Animals; Biopsy; Calcitonin Gene-Related Peptide; Dermatitis; Dinitrochlorobenzene; Disease | 2015 |
Oral supplementation with fish oil reduces dryness and pruritus in the acetone-induced dry skin rat model.
Topics: Acetone; Administration, Oral; Animals; Behavior, Animal; Dietary Supplements; Disease Models, Anima | 2015 |
Enhanced itch elicited by capsaicin in a chronic itch model.
Topics: Acetone; Animals; Behavior, Animal; Capsaicin; Chronic Disease; Disease Models, Animal; Ether; Femal | 2016 |
[Establishment of a SD rat model of vulvar lichen simplex chronicus and detection of the expression of protease activated receptor 2].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; Disease Models, Animal; Female; Fri | 2017 |
Pharmacodynamic and pharmacokinetic interactions between common antiepileptic drugs and acetone, the chief anticonvulsant ketone body elevated in the ketogenic diet in mice.
Topics: Acetone; Animals; Anticonvulsants; Biophysical Phenomena; Disease Models, Animal; Dose-Response Rela | 2009 |
Comparison of voiding function and nociceptive behavior in two rat models of cystitis induced by cyclophosphamide or acetone.
Topics: Acetone; Administration, Intravesical; Animals; Cyclophosphamide; Cystitis; Disease Models, Animal; | 2010 |
1H-nuclear magnetic resonance spectroscopy-based metabolic assessment in a rat model of obesity induced by a high-fat diet.
Topics: Acetoacetates; Acetone; Animals; Betaine; Citric Acid; Dietary Fats; Disease Models, Animal; Glycine | 2009 |
Gelatin nanocarriers as potential vectors for effective management of tuberculosis.
Topics: Acetone; Administration, Oral; Animals; Antibiotics, Antitubercular; Area Under Curve; Cell Line; Ce | 2010 |
Chronic acetonemia alters liver oxidative balance and lipid content in rats. A model of NASH?
Topics: Acetone; Animals; Blood Glucose; Cholesterol; Chronic Disease; Disease Models, Animal; Fatty Liver; | 2010 |
Behavioral and anatomical characterization of the bilateral sciatic nerve chronic constriction (bCCI) injury: correlation of anatomic changes and responses to cold stimuli.
Topics: Acetone; Analgesics; Animals; Biomarkers; Cholecystokinin; Chronic Disease; Cold Temperature; Diseas | 2010 |
Anticonvulsant effects of methyl ethyl ketone and diethyl ketone in several types of mouse seizure models.
Topics: Acetone; Animals; Anticonvulsants; Butanones; Carbolines; Disease Models, Animal; Electroshock; Kain | 2010 |
Designing of mouse model: a new approach for studying sulphur mustard-induced skin lesions.
Topics: Acetone; Animals; Blood Cell Count; Body Weight; Burns, Chemical; Chemical Warfare Agents; Disease M | 2011 |
Enhanced responses of lumbar superficial dorsal horn neurons to intradermal PAR-2 agonist but not histamine in a mouse hindpaw dry skin itch model.
Topics: Acetone; Action Potentials; Analysis of Variance; Animals; Antipruritics; Capsaicin; Disease Models, | 2011 |
Cardioprotective activity of standardized extract of Ficus racemosa stem bark against doxorubicin-induced toxicity.
Topics: Acetone; Alanine Transaminase; Animals; Antibiotics, Antineoplastic; Aspartate Aminotransferases; Bi | 2012 |
Antihyperalgesic effects of clomipramine and tramadol in a model of posttraumatic trigeminal neuropathic pain in mice.
Topics: Acetone; Analgesics, Opioid; Animals; Capsaicin; Clomipramine; Disease Models, Animal; Formaldehyde; | 2011 |
Evaluation of aqueous and ethanolic extracts of saffron, Crocus sativus L., and its constituents, safranal and crocin in allodynia and hyperalgesia induced by chronic constriction injury model of neuropathic pain in rats.
Topics: Acetone; Amines; Analgesics; Animals; Behavior, Animal; Carotenoids; Constriction; Crocus; Cyclohexa | 2012 |
Anti-inflammatory, wound healing and in-vivo antioxidant properties of the leaves of Ficus amplissima Smith.
Topics: Acetone; Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, | 2013 |
The acetone soluble fraction from bark extract of Stryphnodendron adstringens (Mart.) coville inhibits gastric acid secretion and experimental gastric ulceration in rats.
Topics: Acetone; Administration, Oral; Animals; Anti-Ulcer Agents; Disease Models, Animal; Fabaceae; Gastric | 2002 |
Spinal c-fos expression associated with spontaneous biting in a mouse model of dry skin pruritus.
Topics: Acetone; Afferent Pathways; Animals; Dermatitis, Atopic; Disease Models, Animal; Ether; Functional L | 2004 |
Hypoglycaemic and antidiabetic activity of acetonic extract of Vernonia colorata leaves in normoglycaemic and alloxan-induced diabetic rats.
Topics: Acetone; Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Mode | 2005 |
Characterization of a model of cutaneous inflammatory pain produced by an ultraviolet irradiation-evoked sterile injury in the rat.
Topics: Acetone; Animals; Cold Temperature; Disease Models, Animal; Hyperalgesia; Inflammation; Male; Nocice | 2005 |
A ketogenic diet and diallyl sulfide do not elevate afterdischarge thresholds in adult kindled rats.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Allyl Compounds; Analysis of Variance; Animals; Antic | 2006 |
Use of IC tags in short-term carcinogenicity study on CB6F1 TGrasH2 mice.
Topics: Acetone; Animal Identification Systems; Animals; Carcinogenicity Tests; Carcinogens; Disease Models, | 2006 |
The anticonvulsant activity of acetone, the major ketone body in the ketogenic diet, is not dependent on its metabolites acetol, 1,2-propanediol, methylglyoxal, or pyruvic acid.
Topics: Acetone; Animals; Anticonvulsants; Diet Therapy; Disease Models, Animal; Epilepsy; Ketone Bodies; Ma | 2007 |
What is the antiseizure activity of acetone due to?
Topics: Acetone; Animals; Anticonvulsants; Behavior, Animal; Brain; Disease Models, Animal; Drug Contaminati | 2007 |
Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): impact of vehicle for topical induction.
Topics: Acetone; Administration, Inhalation; Administration, Topical; Animals; Asthma; Bronchoalveolar Lavag | 2008 |
The anticonvulsant activity of acetone does not depend upon its metabolites.
Topics: Acetone; Animals; Anticonvulsants; Blood-Brain Barrier; Disease Models, Animal; Humans; Injections, | 2008 |
Hamster tongue carcinogenesis II. Quantitative morphologic aspects of preneoplastic epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Cricetinae; Disease Models, Animal; Epithelium; | 1981 |
Nonspecific hypersensitivity: false-positive responses with the use of Freund's complete adjuvant.
Topics: Acetone; Animals; Disease Models, Animal; Dose-Response Relationship, Immunologic; False Positive Re | 1996 |
Irritable bladder syndrome in an animal model: a continuous monitoring study.
Topics: Acetone; Animals; Chlorocebus aethiops; Disease Models, Animal; Electromyography; Female; Instillati | 1995 |
The efficacy of different moisturizers on barrier recovery in hairless mice evaluated by non-invasive bioengineering methods. A model to select the potentially most effective product.
Topics: Acetone; Animals; Anti-Infective Agents, Local; Cell Membrane Permeability; Chlorhexidine; Dermatiti | 1997 |
Acute cutaneous barrier perturbation induces maturation of Langerhans' cells in hairless mice.
Topics: Acetone; Animals; Antigen Presentation; Antigens, CD; Cell Adhesion Molecules; Cell Differentiation; | 1997 |
Acetone has anti-inflammatory effects on experimental contact reactions.
Topics: Acetone; Administration, Topical; Animals; Anti-Inflammatory Agents; Budesonide; Dermatitis, Contact | 1999 |
Effects of AH-9700, (+)-pentazocine, DTG and oxybutynin on micturition in anesthetized rats with acetone-induced cystitis.
Topics: Acetone; Anesthesia; Animals; Cystitis; Disease Models, Animal; Fumarates; Guanidines; Male; Mandeli | 2001 |
[Induction of atopic dermatitis-like skin lesion in NC/Nga mice--the influence of the skin barrier destroying solution to the induction of dermatitis].
Topics: Acetone; Animals; Dermatitis, Atopic; Disease Models, Animal; Ethanol; Female; Mice; Mice, Inbred BA | 2001 |
Carcinogenesis in an immunologically privileged site.
Topics: Acetone; Administration, Topical; Animals; Cheek; Cricetinae; Disease Models, Animal; Drug Implants; | 1975 |
An animal model for extracorporeal photochemotherapy based on contact hypersensitivity.
Topics: Acetone; Allergens; Animals; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Immu | 1992 |
Uroporphyria caused by acetone and 5-aminolevulinic acid in iron-loaded mice.
Topics: Acetone; Aminolevulinic Acid; Animals; Disease Models, Animal; Drug Interactions; Iron-Dextran Compl | 1989 |
[Experimental protective immunization of mice against S. typhimurium infection by Salmonella R mutants].
Topics: Acetone; Animals; Antigens, Bacterial; Bacterial Vaccines; Bacteriophage Typing; Disease Models, Ani | 1974 |
A rat model of alcoholism?
Topics: Acetone; Alcohol Drinking; Alcoholism; Animal Nutritional Physiological Phenomena; Animals; Conditio | 1972 |
Studies on enteropathogenic activity of Vibrio parahaemolyticus using ligated gut loop model in rabbits.
Topics: Acetone; Animals; Chloroform; Diarrhea; Disease Models, Animal; Gastroenteritis; Intestinal Diseases | 1974 |
Protection against long ultraviolet light with dihydroxyacetone-naphthoquinone.
Topics: Acetone; Animals; Coumarins; Disease Models, Animal; Naphthoquinones; Photosensitivity Disorders; Ra | 1973 |
Renal factor responsible for acute vascular lesions in experimental renovascular hypertension.
Topics: Acetone; Acute Disease; Animals; Blood Pressure; Blood Vessels; Brain; Chromatography; Disease Model | 1969 |
Effects of beta-receptor blockade on the course of experimental hemorrhagic shock.
Topics: Acetone; Animals; Blood; Blood Glucose; Carbon Dioxide; Disease Models, Animal; Dogs; Hematocrit; He | 1969 |
Schedule-induced consumption of ethanol: calories or chemotherapy?
Topics: Acetone; Alcohol Drinking; Alcoholism; Animal Nutritional Physiological Phenomena; Animals; Behavior | 1970 |