Compounds > acetone
Page last updated: 2024-10-16

acetone and Diabetes Mellitus, Type 1

acetone has been researched along with Diabetes Mellitus, Type 1 in 38 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.

Research Excerpts

ExcerptRelevanceReference
" We report a particularly severe clinical problem produced by the combination of toluene intoxication and diabetic ketoacidosis."7.68Solvent abuse, toluene acidosis and diabetic ketoacidosis. ( Brown, JH; Hadden, DR; Hadden, DS, 1991)
" We report a particularly severe clinical problem produced by the combination of toluene intoxication and diabetic ketoacidosis."3.68Solvent abuse, toluene acidosis and diabetic ketoacidosis. ( Brown, JH; Hadden, DR; Hadden, DS, 1991)
"People with type 1 diabetes frequently encounter elevated levels of the ketone bodies acetoacetate (AA), beta-hydroxybutyrate (BHB), and acetone (ACE)."2.69Hyperketonemia can increase lipid peroxidation and lower glutathione levels in human erythrocytes in vitro and in type 1 diabetic patients. ( Jain, SK; McVie, R, 1999)
"Respectively, 3 healthy volunteer and 5 type 1 diabetes mellitus subjects with reverse trend were selected."1.42A Negative Correlation Between Blood Glucose and Acetone Measured in Healthy and Type 1 Diabetes Mellitus Patient Breath. ( Rydosz, A, 2015)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199022 (57.89)18.7374
1990's5 (13.16)18.2507
2000's0 (0.00)29.6817
2010's10 (26.32)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Hancock, G2
Sharma, S1
Galpin, M1
Lunn, D2
Megson, C2
Peverall, R2
Richmond, G2
Ritchie, GAD1
Owen, KR1
Chien, PJ1
Suzuki, T1
Tsujii, M1
Ye, M1
Minami, I1
Toda, K1
Otsuka, H1
Toma, K1
Arakawa, T1
Araki, K1
Iwasaki, Y1
Shinada, K1
Ogawa, Y1
Mitsubayashi, K1
Langman, LJ1
Jannetto, PJ1
Reichard, RR1
Reinhart, J1
Samudrala, D1
Lammers, G1
Mandon, J1
Blanchet, L1
Schreuder, TH1
Hopman, MT1
Harren, FJ1
Tappy, L1
Cristescu, SM1
Walton, C1
Patel, M1
Pitts, D1
Knight, P1
Hoashi, S1
Evans, M1
Turner, C1
Tuleutaeva, S1
Ashirbekova, Z1
Manapova, D1
Almurat, S1
Kharchenko, V1
Blaikie, TP1
Edge, JA1
Ritchie, GA1
Taylor, D1
Reyes-Reyes, A1
Horsten, RC1
Urbach, HP1
Bhattacharya, N1
Rydosz, A1
Jiang, C1
Sun, M1
Wang, Z1
Chen, Z1
Zhao, X1
Yuan, Y1
Li, Y1
Wang, C1
Rooth, G2
Nicholson, JK1
O'Flynn, MP1
Sadler, PJ1
Macleod, AF1
Juul, SM1
Sönksen, PH1
Smialek, JE1
Levine, B1
Pounder, DJ1
Stevenson, RJ1
Taylor, KK1
Braun, L1
Coffey, MJ1
Puskás, F1
Kardon, T1
Nagy, G1
Conley, AA1
Burchell, B1
Mandl, J1
Jain, SK1
McVie, R1
Brown, JH1
Hadden, DR1
Hadden, DS1
Ostenson, S1
Tassopoulos, CN1
Barnett, D1
Fraser, TR1
Bruck, E1
MacGillivray, MH1
Abdel-Salam, E1
Abdel-Aziz, T1
Hafiez, AA1
el-Sharkawy, S1
Boutros, NZ1
Haslbeck, M1
Kraus, B1
Standl, E1
Mehnert, H2
Cohn, ML1
Hingson, RA1
Narduzzi, JV1
Seddon, JM1
Heese, Hde V1
Müller, WA1
Faloona, GR1
Unger, RH1
Traisman, HS1
Greenwood, RD1
Schulz, B3
Michaelis, D4
Neumann, I1
Schäfer, H3
Wulfert, P2
Grujić, M1
Dorchy, H1
Ernould, C1
François, B1
Geussens, H1
Hens, G1
Loeb, H1
Schlack, H1
Palm, D1
Jochmus, I1
Michael, R1
Jutzi, E1
Jung, V1
Sterky, G1
Constam, GR1
Köhler, E1
Krüger, J1
Holvey, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ketone Monitoring in T1D: Effect of SGLT2i During Usual Care and With Insulin Deficiency[NCT05541484]Phase 420 participants (Anticipated)Interventional2022-10-14Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for acetone and Diabetes Mellitus, Type 1

ArticleYear
The use of a portable breath analysis device in monitoring type 1 diabetes patients in a hypoglycaemic clamp: validation with SIFT-MS data.
    Journal of breath research, 2014, Volume: 8, Issue:3

    Topics: Acetone; Blood Glucose; Breath Tests; Calibration; Diabetes Mellitus, Type 1; Exhalation; Glucose Cl

2014
Hyperketonemia can increase lipid peroxidation and lower glutathione levels in human erythrocytes in vitro and in type 1 diabetic patients.
    Diabetes, 1999, Volume: 48, Issue:9

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Child; Diabetes Mellitus, Type 1; Erythrocytes; Gluta

1999

Other Studies

36 other studies available for acetone and Diabetes Mellitus, Type 1

ArticleYear
The correlation between breath acetone and blood betahydroxybutyrate in individuals with type 1 diabetes.
    Journal of breath research, 2020, 10-29, Volume: 15, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetone; Breath Tests; Capillaries; Diabetes Mellitus, Type 1; Diabetic Ketoa

2020
Biochemical Gas Sensors (Biosniffers) Using Forward and Reverse Reactions of Secondary Alcohol Dehydrogenase for Breath Isopropanol and Acetone as Potential Volatile Biomarkers of Diabetes Mellitus.
    Analytical chemistry, 2017, 11-21, Volume: 89, Issue:22

    Topics: 2-Propanol; Acetone; Adult; Aged; Alcohol Dehydrogenase; Biomarkers; Breath Tests; Diabetes Mellitus

2017
A Potentially Volatile Situation.
    Clinical chemistry, 2019, Volume: 65, Issue:4

    Topics: 2-Propanol; Acetone; Adult; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Humans; Male

2019
Early Detection of Diabetic Ketoacidosis by Breathalyzer in a Sailor Reporting for Duty.
    Military medicine, 2019, 12-01, Volume: 184, Issue:11-12

    Topics: Acetone; Adult; Breath Tests; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Early Diagnosis; Hum

2019
Breath acetone to monitor life style interventions in field conditions: an exploratory study.
    Obesity (Silver Spring, Md.), 2014, Volume: 22, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetone; Adult; Aged; Breath Tests; Case-Control Studies; Diabetes Mellitus,

2014
[Periodontal disease in children with diabetes mellitus type 1].
    Georgian medical news, 2014, Issue:235

    Topics: Acetone; Adolescent; Blood Glucose; Child; Diabetes Complications; Diabetes Mellitus, Type 1; Female

2014
Comparison of breath gases, including acetone, with blood glucose and blood ketones in children and adolescents with type 1 diabetes.
    Journal of breath research, 2014, Nov-25, Volume: 8, Issue:4

    Topics: Acetone; Adolescent; Adult; Blood Glucose; Breath Tests; Butadienes; Child; Diabetes Mellitus, Type

2014
Study of the exhaled acetone in type 1 diabetes using quantum cascade laser spectroscopy.
    Analytical chemistry, 2015, Jan-06, Volume: 87, Issue:1

    Topics: Acetone; Adolescent; Adult; Blood Glucose; Breath Tests; Case-Control Studies; Diabetes Mellitus, Ty

2015
A Negative Correlation Between Blood Glucose and Acetone Measured in Healthy and Type 1 Diabetes Mellitus Patient Breath.
    Journal of diabetes science and technology, 2015, Volume: 9, Issue:4

    Topics: Acetone; Adult; Blood Glucose; Breath Tests; Diabetes Mellitus, Type 1; Exhalation; Female; Glucose

2015
A Portable Real-Time Ringdown Breath Acetone Analyzer: Toward Potential Diabetic Screening and Management.
    Sensors (Basel, Switzerland), 2016, Jul-30, Volume: 16, Issue:8

    Topics: Acetone; Blood Glucose; Breath Tests; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gas Chro

2016
Insulin action measured by acetone disappearance. Preliminary report.
    Acta medica Scandinavica, 1967, Volume: 182, Issue:2

    Topics: Acetone; Adolescent; Adult; Aged; Chromatography, Gas; Diabetes Mellitus; Diabetes Mellitus, Type 1;

1967
Proton-nuclear-magnetic-resonance studies of serum, plasma and urine from fasting normal and diabetic subjects.
    The Biochemical journal, 1984, Jan-15, Volume: 217, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adult; Amino Acids; Diabetes Mellitus, Type 1; Diabet

1984
Diabetes and decomposition: a case of diabetic ketoacidosis with advanced postmortem change.
    The American journal of forensic medicine and pathology, 1998, Volume: 19, Issue:1

    Topics: Acetone; Adolescent; Adult; Blood Glucose; Cause of Death; Child; Chromatography, Gas; Diabetes Mell

1998
Alcoholic ketoacidosis at autopsy.
    Journal of forensic sciences, 1998, Volume: 43, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Alcoholis

1998
Molecular basis of bilirubin UDP-glucuronosyltransferase induction in spontaneously diabetic rats, acetone-treated rats and starved rats.
    The Biochemical journal, 1998, Dec-15, Volume: 336 ( Pt 3)

    Topics: Acetone; Animals; Diabetes Mellitus, Type 1; Electrophoresis, Polyacrylamide Gel; Enzyme Induction;

1998
Solvent abuse, toluene acidosis and diabetic ketoacidosis.
    Archives of emergency medicine, 1991, Volume: 8, Issue:1

    Topics: Acetone; Acid-Base Equilibrium; Adult; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Female; Hum

1991
Acetone in alveolar air, and the control of diabetes.
    Lancet (London, England), 1966, Nov-19, Volume: 2, Issue:7473

    Topics: Acetone; Adult; Chromatography, Gas; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fasting; Humans;

1966
Breath-acetone and blood-sugar measurements in diabetes.
    Lancet (London, England), 1969, Jun-28, Volume: 1, Issue:7609

    Topics: Acetone; Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet Therapy; Fasting;

1969
Posthypoglycemic hyperglycemia in diabetic children.
    The Journal of pediatrics, 1974, Volume: 84, Issue:5

    Topics: Acetone; Adolescent; Age Factors; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1;

1974
Suprarenal cortical reserve capacity in juvenile diabetes.
    The Gazette of the Egyptian Paediatric Association, 1974, Volume: 22, Issue:1

    Topics: Acetone; Adolescent; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Child; Circadian R

1974
[Self-control of metabolism in diabetic patients].
    Deutsche medizinische Wochenschrift (1946), 1974, Oct-25, Volume: 99, Issue:43

    Topics: Acetone; Adolescent; Adult; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Evaluation Studies

1974
Clinical experience with jet insulin injection in diabetes mellitus therapy: a clue to the pathogenesis of lipodystrophy.
    The Alabama journal of medical sciences, 1974, Volume: 11, Issue:3

    Topics: Acetone; Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Evalu

1974
The infant of the diabetic mother.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Apr-15, Volume: 46, Issue:16

    Topics: Acetone; Adipose Tissue; Birth Injuries; Birth Weight; Diabetes Mellitus, Type 1; Female; Gastrointe

1972
Hyperglucagonemia in diabetic ketoacidosis. Its prevalence and significance.
    The American journal of medicine, 1973, Volume: 54, Issue:1

    Topics: Acetone; Adolescent; Adult; Aged; Blood Glucose; Blood Urea Nitrogen; Carbon Dioxide; Child; Chlorid

1973
[Juvenile diabetes].
    Deutsche medizinische Wochenschrift (1946), 1972, Dec-15, Volume: 97, Issue:50

    Topics: Acetone; Adolescent; Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Male

1972
A comparative clinical evaluation of a new proprietary method for urine testing in juvenile diabetics.
    Clinical pediatrics, 1973, Volume: 12, Issue:6

    Topics: Acetone; Adolescent; Child; Costs and Cost Analysis; Diabetes Mellitus, Type 1; Evaluation Studies a

1973
[The effect of the lipolysis blocker 5-methylpyrazol-3-carbonic acid (MPC) on changes in carbohydrate and lipid metabolism induced by muscle work in insulin-requiring diabetics].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Jun-15, Volume: 28, Issue:12

    Topics: Acetone; Adult; Blood Glucose; Carboxylic Acids; Diabetes Mellitus, Type 1; Dietary Carbohydrates; D

1973
[Oscillatory diabetes mellitus (Brittle diabetes)].
    Medicinski arhiv, 1974, Volume: 28, Issue:2

    Topics: Acetone; Adolescent; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Humans; Syndrome

1974
[Guide for the young diabetic: 4th lesson. Urinalysis: when? how? why?].
    Revue medicale de Liege, 1972, Jul-15, Volume: 27, Issue:14

    Topics: Acetone; Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Glycosuria; Health Educatio

1972
[Influence of recurrent hypoglycemia on the EEG of the diabetic child].
    Monatsschrift fur Kinderheilkunde, 1969, Volume: 117, Issue:4

    Topics: Acetone; Child; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Electroencephalography; Humans

1969
[Muscular exertion and diabetes mellitus. Substrate and metabolite changes in blood by acute exertion load in diabetics with stabile and labile metabolism].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1969, Volume: 29, Issue:4

    Topics: Acetone; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise Test; Fatty Acids; Glucose Tolera

1969
[Muscle work and diabetes mellitus. II. Influence of subliminal insulin doses on the carbohydrate and lipid metabolism under acute work-load].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1970, Volume: 30, Issue:3

    Topics: Acetone; Adult; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Type 1; Fasting; Fatty Ac

1970
[Ambulatory care for the diabetic child].
    Archiv fur Kinderheilkunde, 1968

    Topics: Acetone; Adult; Ambulatory Care; Child; Child Care; Diabetes Mellitus, Type 1; Diet Therapy; Dieteti

1968
[Care for the diabetic child. Results of pediatric care from the internist's view point].
    Archiv fur Kinderheilkunde, 1968

    Topics: Acetone; Age Factors; Blood Glucose; Child; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabet

1968
[Studies on the circadian rhythm of somatotropin and hydrocortisone secretion subjects with normal metabolism and with diabetes].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1968, Aug-01, Volume: 23, Issue:15

    Topics: Acetone; Adolescent; Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Fatty Acids,

1968
Surgery in the child with diabetes.
    Pediatric clinics of North America, 1969, Volume: 16, Issue:3

    Topics: Acetone; Anesthesia; Blood Glucose; Child; Diabetes Mellitus, Type 1; Emergencies; Glucose; Glycosur

1969