Page last updated: 2024-10-16

acetone and Cystic Fibrosis

acetone has been researched along with Cystic Fibrosis in 5 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
"Elevated concentrations of hydrogen cyanide (HCN) have been detected in the headspace of Pseudomonas aeruginosa (PA) cultures and in the breath of children with cystic fibrosis (CF) and PA infection."7.79Hydrogen cyanide concentrations in the breath of adult cystic fibrosis patients with and without Pseudomonas aeruginosa infection. ( Bright-Thomas, RJ; Gilchrist, FJ; Jones, AM; Lenney, W; Smith, D; Spaněl, P; Webb, AK, 2013)
"Elevated concentrations of hydrogen cyanide (HCN) have been detected in the headspace of Pseudomonas aeruginosa (PA) cultures and in the breath of children with cystic fibrosis (CF) and PA infection."3.79Hydrogen cyanide concentrations in the breath of adult cystic fibrosis patients with and without Pseudomonas aeruginosa infection. ( Bright-Thomas, RJ; Gilchrist, FJ; Jones, AM; Lenney, W; Smith, D; Spaněl, P; Webb, AK, 2013)
" The levels of ethane, propane, n-pentane, methanol, ethanol, 2-propanol, acetone, isoprene, benzene, toluene, dimethyl sulphide (DMS) and limonene were measured in repeated breath samples from 20 cystic fibrosis patients and 20 healthy controls (aged 8-29 yrs)."3.73Volatile organic compounds in the exhaled breath of young patients with cystic fibrosis. ( Barker, M; Buers, HJ; Hengst, M; Klemp, D; Koppmann, R; Mittermaier, B; Schmid, J, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
White, IR1
Willis, KA1
Whyte, C1
Cordell, R1
Blake, RS1
Wardlaw, AJ1
Rao, S1
Grigg, J1
Ellis, AM1
Monks, PS1
Gilchrist, FJ1
Bright-Thomas, RJ1
Jones, AM1
Smith, D1
Spaněl, P1
Webb, AK1
Lenney, W1
Montuschi, P1
Paris, D1
Melck, D1
Lucidi, V1
Ciabattoni, G1
Raia, V1
Calabrese, C1
Bush, A1
Barnes, PJ1
Motta, A1
Barker, M1
Hengst, M1
Schmid, J1
Buers, HJ1
Mittermaier, B1
Klemp, D1
Koppmann, R1
Claass, A1
Sommer, M1
de Jonge, H1
Kälin, N1
Tümmler, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Determining the Effect of Probiotics on Microbiome and Volatile Organic Compounds in Patients After Surgical Repair of Congenital Diaphragmatic Hernia[NCT03787160]18 participants (Actual)Interventional2018-03-22Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

5 other studies available for acetone and Cystic Fibrosis

ArticleYear
Real-time multi-marker measurement of organic compounds in human breath: towards fingerprinting breath.
    Journal of breath research, 2013, Volume: 7, Issue:1

    Topics: Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Breath Tests; Central Nervous System Depressant

2013
Hydrogen cyanide concentrations in the breath of adult cystic fibrosis patients with and without Pseudomonas aeruginosa infection.
    Journal of breath research, 2013, Volume: 7, Issue:2

    Topics: Acetone; Adult; Biomarkers; Breath Tests; Cystic Fibrosis; Exhalation; Female; Follow-Up Studies; Hu

2013
NMR spectroscopy metabolomic profiling of exhaled breath condensate in patients with stable and unstable cystic fibrosis.
    Thorax, 2012, Volume: 67, Issue:3

    Topics: 2-Propanol; Acetates; Acetone; Adolescent; Biomarkers; Breath Tests; Child; Cross-Sectional Studies;

2012
Volatile organic compounds in the exhaled breath of young patients with cystic fibrosis.
    The European respiratory journal, 2006, Volume: 27, Issue:5

    Topics: 2-Propanol; Acetone; Adolescent; Adult; Benzene; Breath Tests; Butadienes; Child; Cyclohexenes; Cyst

2006
Applicability of different antibodies for immunohistochemical localization of CFTR in sweat glands from healthy controls and from patients with cystic fibrosis.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2000, Volume: 48, Issue:6

    Topics: Acetone; Antibodies; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Health St

2000