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acetone and Cell Transformation, Neoplastic

acetone has been researched along with Cell Transformation, Neoplastic in 20 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
" It was found that induction of epidermal hyperplasia, with either a mixture of turpentine and acetone or phorbol esters, produced a marked increase in papilloma yield."3.69High efficiency induction of papillomas in vivo using recombinant cottontail rabbit papillomavirus DNA. ( Bower, JM; Christensen, ND; Cladel, NM; DiAngelo, SL; Kreider, JW; Patrick, SD; Welsh, PA, 1995)
"It is known that the free-radical-generating compound, benzoyl peroxide (BPO) enhances malignant conversion of murine skin benign papillomas into carcinomas."3.67Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds. ( Athar, M; Bickers, DR; Lloyd, JR; Mukhtar, H, 1989)
"D/T/D/T mice developed squamous cell carcinomas (SCCs) 10 weeks earlier than D/T/A/T mice and demonstrated a 96% malignancy incidence and 1."1.30A multihit, multistage model of chemical carcinogenesis. ( Owens, DM; Smart, RC; Wei, S, 1999)
"The papillomas are heterogeneous in their potential for progression to carcinomas, a property apparently induced at the time of initiation."1.28Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin. ( Hennings, H, 1991)
" This study was done to determine if Balbc/3T3 cells exposed to extracts of air samples could, unlike their normal counterparts, in the absence of a surface for attachment, divide on agar to form aggregates, and if these cells would demonstrate a dose-response phenomenon."1.27Balbc/3T3 cell transformation response to extracts of organic air samples as seen by their survival in aggregate form. ( Daisey, JM; Kneip, TJ; Traul, KA; Zelikoff, JT, 1985)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199015 (75.00)18.7374
1990's3 (15.00)18.2507
2000's1 (5.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bility, MT1
Devlin-Durante, MK1
Blazanin, N1
Glick, AB1
Ward, JM1
Kang, BH1
Kennett, MJ1
Gonzalez, FJ1
Peters, JM1
Ferrucio, B1
Franchi, CA1
Boldrin, NF1
de Oliveira, ML1
de Camargo, JL1
SETALA, K1
STJERNVALL, L1
NYHOLM, M1
MERENMIES, L1
NISKANEN, EE1
AHO, Y1
POUND, AW1
WITHERS, HR1
ARGUS, MF1
ARCOS, JC1
Marks, F1
Fürstenberger, G1
Kreider, JW1
Cladel, NM1
Patrick, SD1
Welsh, PA1
DiAngelo, SL1
Bower, JM1
Christensen, ND1
Owens, DM1
Wei, S1
Smart, RC1
Evans, CH1
DiPaolo, JA1
Hennings, H1
Athar, M1
Lloyd, JR1
Bickers, DR1
Mukhtar, H1
Chu, KC1
Brown, CC1
Tarone, RE1
Tan, WY1
von Hofe, EH1
Billings, PC1
Heidelberger, C1
Landolph, JR1
Yavelow, J1
Collins, M1
Birk, Y1
Troll, W1
Kennedy, AR1
Zelikoff, JT1
Daisey, JM1
Traul, KA1
Kneip, TJ1
Rhim, JS2
Cho, HY1
Rabstein, L1
Gordon, RJ2
Bryan, RJ2
Gardner, MB1
Huebner, RJ2
Crocker, TT1
O'Donnell, TV1
Nunes, LL1
Marquardt, H1
Sodergren, JE1
Sims, P1
Grover, PL1
Roe, FJ1
Carter, RL1
Mitchley, BC1
Peto, R1
Hecker, E1

Other Studies

20 other studies available for acetone and Cell Transformation, Neoplastic

ArticleYear
Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) inhibits chemically induced skin tumorigenesis.
    Carcinogenesis, 2008, Volume: 29, Issue:12

    Topics: Acetone; Animals; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neopla

2008
Evaluation of diuron (3-[3,4-dichlorophenyl]-1,1-dimethyl urea) in a two-stage mouse skin carcinogenesis assay.
    Toxicologic pathology, 2010, Volume: 38, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogenicity Tests; Carcinogens; Cell Transfo

2010
Mechanism of experimental tumorigenesis. 7. Ultrastructural changes in mouse epidermis caused by glyceryl sterate-type tumor enhancers in acetone and in water.
    Acta pathologica et microbiologica Scandinavica, 1961, Volume: 51

    Topics: Acetone; Animals; Cell Transformation, Neoplastic; Epidermis; Mice; Neoplasms, Experimental; Stearat

1961
THE INFLUENCE OF SOME IRRITANT CHEMICALS AND SCARIFICATION ON TUMOUR INITIATION BY URETHANE IN MICE.
    British journal of cancer, 1963, Volume: 17

    Topics: Acetates; Acetone; Cantharidin; Cell Transformation, Neoplastic; Dermabrasion; Iodoacetates; Irritan

1963
FAILURE OF MONO-CHLOROACETONE TO INFLUENCE 3,4-BENZPYRENE MOUSE SKIN TUMORIGENESIS.
    Experientia, 1963, Nov-15, Volume: 19

    Topics: Acetone; Animals; Antineoplastic Agents; Benzo(a)pyrene; Benzopyrenes; Cell Transformation, Neoplast

1963
Stages of tumour promotion in skin.
    IARC scientific publications, 1984, Issue:56

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Aging; Animals; Animals, Newborn; Carcinogens; Cell Divis

1984
High efficiency induction of papillomas in vivo using recombinant cottontail rabbit papillomavirus DNA.
    Journal of virological methods, 1995, Volume: 55, Issue:2

    Topics: Acetone; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cottontail rabbit pap

1995
A multihit, multistage model of chemical carcinogenesis.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Tran

1999
Neoplastic transformation of guinea pig fetal cells in culture induced by chemical carcinogens.
    Cancer research, 1975, Volume: 35, Issue:4

    Topics: Acetone; Aflatoxins; Amides; Animals; Benz(a)Anthracenes; Carcinogens; Cell Division; Cell Transform

1975
Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin.
    Basic life sciences, 1991, Volume: 57

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Ce

1991
Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds.
    Carcinogenesis, 1989, Volume: 10, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Amidines; Animals; Benzoyl Peroxide; Carcinogens; Cell Tr

1989
Differentiating among proposed mechanisms for tumor promotion in mouse skin with the use of the multievent model for cancer.
    Journal of the National Cancer Institute, 1987, Volume: 79, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Acetone; Animals; Cell Transformation, Neoplastic; Mathematics; Mice; Mode

1987
In vitro genotoxicity studies using complex hydrophobic mixtures: efficient delivery of a petroleum sample to cultured C3H/10T1/2 cells via lipid vesicle incorporation.
    Environmental mutagenesis, 1986, Volume: 8, Issue:4

    Topics: Acetone; Alkanes; Animals; Benzo(a)pyrene; Carbon Radioisotopes; Cell Survival; Cell Transformation,

1986
Nanomolar concentrations of Bowman-Birk soybean protease inhibitor suppress x-ray-induced transformation in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:16

    Topics: Acetone; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chymotrypsin; Mice; Mice, Inbred

1985
Balbc/3T3 cell transformation response to extracts of organic air samples as seen by their survival in aggregate form.
    Mutation research, 1985, Volume: 144, Issue:2

    Topics: Acetone; Air Pollutants; Animals; Cell Adhesion; Cell Line; Cell Survival; Cell Transformation, Neop

1985
Transformation of mouse cells infected with AKR leukaemia virus induced by smog extracts.
    Nature, 1972, Sep-08, Volume: 239, Issue:5367

    Topics: Acetone; Air Pollution; Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Cell Transformation,

1972
Transformation of mouse cells infected with AKR leukemia virus by benzene extact fractions of city air particles.
    International journal of cancer, 1973, Sep-15, Volume: 12, Issue:2

    Topics: Acetone; Animals; Benzene; Benzopyrenes; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Ce

1973
Toxicity of benzo( )pyrene and air pollution composite for adult human bronchial mucosa in organ culture.
    Cancer research, 1973, Volume: 33, Issue:1

    Topics: Acetone; Adult; Aged; Air Pollution; Autoradiography; Benzopyrenes; Bronchi; Carcinoma, Bronchogenic

1973
Malignant transformation in vitro of mouse fibroblasts by 7,12-dimethylbenz(A)anthracene and 7-hydroxymethylbenz(A)anthracene and by their K-region derivatives.
    International journal of cancer, 1974, Mar-15, Volume: 13, Issue:3

    Topics: Acetone; Animals; Benz(a)Anthracenes; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; C

1974
On the persistence of tumour initiation and the acceleration of tumour progression in mouse skin tumorigenesis.
    International journal of cancer, 1972, Mar-15, Volume: 9, Issue:2

    Topics: Acetone; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Croton Oil; Female; Mice; Neo

1972