acetone has been researched along with Brain Neoplasms in 9 studies
methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Reference |
|---|---|
| "Recurrent malignant brain tumors (RMBTs) carry a poor prognosis." | ( Coats, BS; Dunbar, EM; Forder, JR; Langaee, T; Lew, A; Shroads, AL; Shuster, JJ; Stacpoole, PW; Wagner, DA, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Helal, DO | 1 |
| Abdel-Mottaleb, MMA | 1 |
| Kamel, AO | 1 |
| Rouatbi, N | 1 |
| Han, S | 1 |
| Geneidi, AS | 1 |
| Al-Jamal, KT | 1 |
| Awad, GAS | 1 |
| Dunbar, EM | 1 |
| Coats, BS | 1 |
| Shroads, AL | 1 |
| Langaee, T | 1 |
| Lew, A | 1 |
| Forder, JR | 1 |
| Shuster, JJ | 1 |
| Wagner, DA | 1 |
| Stacpoole, PW | 1 |
| Galli, R | 1 |
| Uckermann, O | 1 |
| Koch, E | 1 |
| Schackert, G | 1 |
| Kirsch, M | 1 |
| Steiner, G | 1 |
| Kim, D | 1 |
| Fiske, BP | 1 |
| Birsoy, K | 1 |
| Freinkman, E | 1 |
| Kami, K | 1 |
| Possemato, RL | 1 |
| Chudnovsky, Y | 1 |
| Pacold, ME | 1 |
| Chen, WW | 1 |
| Cantor, JR | 1 |
| Shelton, LM | 1 |
| Gui, DY | 1 |
| Kwon, M | 1 |
| Ramkissoon, SH | 1 |
| Ligon, KL | 1 |
| Kang, SW | 1 |
| Snuderl, M | 1 |
| Vander Heiden, MG | 1 |
| Sabatini, DM | 1 |
| Kim, TH | 1 |
| Jeong, YI | 1 |
| Jin, SG | 1 |
| Pei, J | 1 |
| Jung, TY | 1 |
| Moon, KS | 1 |
| Kim, IY | 1 |
| Kang, SS | 1 |
| Jung, S | 1 |
| KRUMBHOLZ, S | 1 |
| SUZUKI, M | 1 |
| KAWAKATSU, T | 1 |
| KAMOSHITA, S | 1 |
| KAWAGUCHI, H | 1 |
| SUZUKI, Y | 1 |
| Kerr, MA | 1 |
| Nasca, PC | 1 |
| Mundt, KA | 1 |
| Michalek, AM | 1 |
| Baptiste, MS | 1 |
| Mahoney, MC | 1 |
| Mahajan, DK | 1 |
| Shah, PN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Trial of Dichloroacetate (DCA) in Glioblastoma Multiforme (GBM)[NCT05120284] | Phase 2 | 40 participants (Anticipated) | Interventional | 2022-07-01 | Recruiting | ||
| Phase 3 Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:[NCT02616484] | Phase 3 | 34 participants (Actual) | Interventional | 2020-07-14 | Active, not recruiting | ||
| Phase 1, Open-Label, Single-Arm, Clinical and Metabolomics Study of Dichloroacetate (DCA) in Adults With Recurrent Malignant Brain Tumors[NCT01111097] | Phase 1 | 15 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial(s) available for acetone and Brain Neoplasms
| Article | Year |
|---|---|
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brain Neoplasms; Breath Tests; Dichloroacetic Acid; Female; Glutathione Transferase; Haplotypes; Humans; Male; Maleates; Middle Aged; Pyruvic Acid | 2014 |
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brain Neoplasms; Breath Tests; Dichloroacetic Acid; Female; Glutathione Transferase; Haplotypes; Humans; Male; Maleates; Middle Aged; Pyruvic Acid | 2014 |
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brain Neoplasms; Breath Tests; Dichloroacetic Acid; Female; Glutathione Transferase; Haplotypes; Humans; Male; Maleates; Middle Aged; Pyruvic Acid | 2014 |
8 other study(ies) available for acetone and Brain Neoplasms
| Article | Year |
|---|---|
The interplay of solvent-drug-protein interactions during albumin nanoparticles formulations for temozolomide delivery to brain cancer cells.
Topics: Acetone; Brain Neoplasms; Cell Line, Tumor; Ethanol; Glioblastoma; Humans; Nanoparticles; Serum Albumin, Human; Solvents; Temozolomide | 2023 |
Effects of tissue fixation on coherent anti-Stokes Raman scattering images of brain.
Topics: Acetone; Animals; Brain; Brain Neoplasms; Central Nervous System; Female; Formaldehyde; Glioblastoma; Histological Techniques; Humans; Image Processing, Computer-Assisted; Lipids; Methanol; Mice; Mice, Nude; Spectrum Analysis, Raman; Tissue Fixation | 2014 |
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
Topics: Acetone; Animals; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Female; Glioblastoma; Glycine; Glycine Dehydrogenase (Decarboxylating); Glycine Hydroxymethyltransferase; Humans; Ischemia; Mice; Necrosis; Oxygen Consumption; Pyruvaldehyde; Pyruvate Kinase; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2015 |
Preparation of polylactide-co-glycolide nanoparticles incorporating celecoxib and their antitumor activity against brain tumor cells.
Topics: Acetone; Animals; Antineoplastic Agents; Brain Neoplasms; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Drug Carriers; Drug Stability; Glioma; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Powder Diffraction; Pyrazoles; Rats; Solvents; Sulfonamides | 2011 |
[On the diagnostic value of the urinary acetone precipitation test in neurosurgical patients].
Topics: Acetone; Brain Neoplasms; Humans; Immune System Phenomena; Neoplasms; Urinary Tract | 1961 |
A CASE OF PONTINE TUMOR ASSOCIATED WITH REPEATED EPISODES OF HYPERVENTILATION AND KETOSIS.
Topics: Acetone; Acidosis; Astrocytoma; Blood Chemical Analysis; Brain Neoplasms; Brain Stem Neoplasms; Child; Electrolytes; Humans; Hyperventilation; Ketone Bodies; Ketosis; Pons; Respiratory Function Tests; Urine | 1964 |
Parental occupational exposures and risk of neuroblastoma: a case-control study (United States).
Topics: Acetone; Adolescent; Brain Neoplasms; Case-Control Studies; Child; Child, Preschool; Female; Humans; Infant; Insecticides; Male; Maternal Exposure; Neuroblastoma; Occupational Exposure; Odds Ratio; Paternal Exposure; Petroleum; Risk Assessment; Risk Factors; United States | 2000 |
Quantitative aspects of gonadotropin inhibiting material: site of origin.
Topics: Acetone; Adult; Alcohols; Animals; Biological Assay; Brain Neoplasms; Chemical Precipitation; Child; Child, Preschool; Chorionic Gonadotropin; Endocrine System Diseases; Female; Gonadotropins; Humans; Hypogonadism; Hypothalamo-Hypophyseal System; Hypothalamus; Kaolin; Male; Methods; Mice; Middle Aged; Urine | 1970 |