acetone has been researched along with Benign Neoplasms, Brain in 9 studies
methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we report the effects of two common fixation methods, namely with formalin and methanol-acetone, on mouse brain and human glioblastoma tissue." | 3.80 | Effects of tissue fixation on coherent anti-Stokes Raman scattering images of brain. ( Galli, R; Kirsch, M; Koch, E; Schackert, G; Steiner, G; Uckermann, O, 2014) |
| " Dosing was based on haplotype variation in glutathione transferase zeta 1/maleylacetoacetate isomerase (GSTZ1/MAAI), which participates in DCA and tyrosine catabolism." | 2.79 | Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors. ( Coats, BS; Dunbar, EM; Forder, JR; Langaee, T; Lew, A; Shroads, AL; Shuster, JJ; Stacpoole, PW; Wagner, DA, 2014) |
| "Celecoxib was incorporated into poly DL-lactide-co-glycolide (PLGA) nanoparticles for antitumor drug delivery." | 1.37 | Preparation of polylactide-co-glycolide nanoparticles incorporating celecoxib and their antitumor activity against brain tumor cells. ( Jeong, YI; Jin, SG; Jung, S; Jung, TY; Kang, SS; Kim, IY; Kim, TH; Moon, KS; Pei, J, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Helal, DO | 1 |
| Abdel-Mottaleb, MMA | 1 |
| Kamel, AO | 1 |
| Rouatbi, N | 1 |
| Han, S | 1 |
| Geneidi, AS | 1 |
| Al-Jamal, KT | 1 |
| Awad, GAS | 1 |
| Dunbar, EM | 1 |
| Coats, BS | 1 |
| Shroads, AL | 1 |
| Langaee, T | 1 |
| Lew, A | 1 |
| Forder, JR | 1 |
| Shuster, JJ | 1 |
| Wagner, DA | 1 |
| Stacpoole, PW | 1 |
| Galli, R | 1 |
| Uckermann, O | 1 |
| Koch, E | 1 |
| Schackert, G | 1 |
| Kirsch, M | 1 |
| Steiner, G | 1 |
| Kim, D | 1 |
| Fiske, BP | 1 |
| Birsoy, K | 1 |
| Freinkman, E | 1 |
| Kami, K | 1 |
| Possemato, RL | 1 |
| Chudnovsky, Y | 1 |
| Pacold, ME | 1 |
| Chen, WW | 1 |
| Cantor, JR | 1 |
| Shelton, LM | 1 |
| Gui, DY | 1 |
| Kwon, M | 1 |
| Ramkissoon, SH | 1 |
| Ligon, KL | 1 |
| Kang, SW | 1 |
| Snuderl, M | 1 |
| Vander Heiden, MG | 1 |
| Sabatini, DM | 1 |
| Kim, TH | 1 |
| Jeong, YI | 1 |
| Jin, SG | 1 |
| Pei, J | 1 |
| Jung, TY | 1 |
| Moon, KS | 1 |
| Kim, IY | 1 |
| Kang, SS | 1 |
| Jung, S | 1 |
| KRUMBHOLZ, S | 1 |
| SUZUKI, M | 1 |
| KAWAKATSU, T | 1 |
| KAMOSHITA, S | 1 |
| KAWAGUCHI, H | 1 |
| SUZUKI, Y | 1 |
| Kerr, MA | 1 |
| Nasca, PC | 1 |
| Mundt, KA | 1 |
| Michalek, AM | 1 |
| Baptiste, MS | 1 |
| Mahoney, MC | 1 |
| Mahajan, DK | 1 |
| Shah, PN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Trial of Dichloroacetate (DCA) in Glioblastoma Multiforme (GBM)[NCT05120284] | Phase 2 | 40 participants (Anticipated) | Interventional | 2022-07-01 | Recruiting | ||
| Phase 3 Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:[NCT02616484] | Phase 3 | 34 participants (Actual) | Interventional | 2020-07-14 | Active, not recruiting | ||
| Phase 1, Open-Label, Single-Arm, Clinical and Metabolomics Study of Dichloroacetate (DCA) in Adults With Recurrent Malignant Brain Tumors[NCT01111097] | Phase 1 | 15 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for acetone and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brai | 2014 |
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brai | 2014 |
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brai | 2014 |
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brai | 2014 |
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brai | 2014 |
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brai | 2014 |
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brai | 2014 |
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brai | 2014 |
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brai | 2014 |
8 other studies available for acetone and Benign Neoplasms, Brain
| Article | Year |
|---|---|
The interplay of solvent-drug-protein interactions during albumin nanoparticles formulations for temozolomide delivery to brain cancer cells.
Topics: Acetone; Brain Neoplasms; Cell Line, Tumor; Ethanol; Glioblastoma; Humans; Nanoparticles; Serum Albu | 2023 |
Effects of tissue fixation on coherent anti-Stokes Raman scattering images of brain.
Topics: Acetone; Animals; Brain; Brain Neoplasms; Central Nervous System; Female; Formaldehyde; Glioblastoma | 2014 |
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
Topics: Acetone; Animals; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Female; Glioblasto | 2015 |
Preparation of polylactide-co-glycolide nanoparticles incorporating celecoxib and their antitumor activity against brain tumor cells.
Topics: Acetone; Animals; Antineoplastic Agents; Brain Neoplasms; Celecoxib; Cell Line, Tumor; Cell Movement | 2011 |
[On the diagnostic value of the urinary acetone precipitation test in neurosurgical patients].
Topics: Acetone; Brain Neoplasms; Humans; Immune System Phenomena; Neoplasms; Urinary Tract | 1961 |
A CASE OF PONTINE TUMOR ASSOCIATED WITH REPEATED EPISODES OF HYPERVENTILATION AND KETOSIS.
Topics: Acetone; Acidosis; Astrocytoma; Blood Chemical Analysis; Brain Neoplasms; Brain Stem Neoplasms; Chil | 1964 |
Parental occupational exposures and risk of neuroblastoma: a case-control study (United States).
Topics: Acetone; Adolescent; Brain Neoplasms; Case-Control Studies; Child; Child, Preschool; Female; Humans; | 2000 |
Quantitative aspects of gonadotropin inhibiting material: site of origin.
Topics: Acetone; Adult; Alcohols; Animals; Biological Assay; Brain Neoplasms; Chemical Precipitation; Child; | 1970 |