Page last updated: 2024-10-16

acetone and Aura

acetone has been researched along with Aura in 13 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

Research Excerpts

ExcerptRelevanceReference
"A 10 mmol/kg injection of acetone suppressed seizures in 60% of rats (P<0."7.71Ketogenic diet: does acetone stop seizures? ( Burnham, WM; Likhodii, SS, 2002)
"Although ketosis is an integral aspect of these therapeutic regimens, the direct importance of ketosis to seizure control needs further investigation."5.31Epilepsy and the ketogenic diet: assessment of ketosis in children using breath acetone. ( Comeau, F; Cunnane, S; Curtis, R; Musa-Veloso, K; Rarama, E, 2002)
"The DNS II acetone fraction of Delphinium nordhagenii has exhibited the anticonvulsant actions by preventing the seizures against PTZ- and picrotoxin-induced seizure as well as 100% seizure protection in MES test."3.76Anticonvulsant activity of DNS II fraction in the acute seizure models. ( Ahmad, M; Raza, ML; Shaheen, F; Simjee, SU; Zeeshan, M, 2010)
"Acetone is the principal ketone body elevated in the ketogenic diet (KD), with demonstrated robust anticonvulsant properties across a variety of seizure tests and models of epilepsy."3.75Pharmacodynamic and pharmacokinetic interactions between common antiepileptic drugs and acetone, the chief anticonvulsant ketone body elevated in the ketogenic diet in mice. ( Buszewicz, G; Czuczwar, SJ; Gasior, M; Luszczki, JJ; Madro, R; Zarnowska, I; Zarnowski, T, 2009)
"A 10 mmol/kg injection of acetone suppressed seizures in 60% of rats (P<0."3.71Ketogenic diet: does acetone stop seizures? ( Burnham, WM; Likhodii, SS, 2002)
"Ketosis is believed to be necessary to the anticonvulsant mechanism of the ketogenic diet; however, the relationship between ketosis and seizure control has not been established."2.42Non-invasive detection of ketosis and its application in refractory epilepsy. ( Musa-Veloso, K, 2004)
"To understand how ketosis and seizure protection are related, a reliable, noninvasive measure of ketosis that can be performed frequently with minimal discomfort is needed."1.31Breath acetone is a reliable indicator of ketosis in adults consuming ketogenic meals. ( Cunnane, SC; Likhodii, SS; Musa-Veloso, K, 2002)
"Although ketosis is an integral aspect of these therapeutic regimens, the direct importance of ketosis to seizure control needs further investigation."1.31Epilepsy and the ketogenic diet: assessment of ketosis in children using breath acetone. ( Comeau, F; Cunnane, S; Curtis, R; Musa-Veloso, K; Rarama, E, 2002)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's1 (7.69)18.2507
2000's7 (53.85)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zarnowska, I1
Luszczki, JJ1
Zarnowski, T1
Buszewicz, G1
Madro, R1
Czuczwar, SJ1
Gasior, M2
Raza, ML1
Zeeshan, M1
Ahmad, M1
Shaheen, F1
Simjee, SU1
Hu, XL1
Cheng, X1
Fei, J1
Xiong, ZQ1
Likhodii, SS3
Burnham, WM2
Musa-Veloso, K3
Rarama, E1
Comeau, F1
Curtis, R1
Cunnane, S1
GAYRAL, L2
French, A1
Joy, MT1
Tang, RS1
Hartman, AL1
Rogawski, MA1
Seymour, KJ1
Bluml, S1
Sutherling, J1
Sutherling, W1
Ross, BD1
Cunnane, SC1
DeVivo, DC1
Pagliara, AS1
Prensky, AL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Characterization of a Portable Solid-State Breath Acetone Testing Device for Real-Time Ketosis Status and Comparison to Blood Ketone Testing[NCT04130724]21 participants (Actual)Observational2019-10-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for acetone and Aura

ArticleYear
Non-invasive detection of ketosis and its application in refractory epilepsy.
    Prostaglandins, leukotrienes, and essential fatty acids, 2004, Volume: 70, Issue:3

    Topics: Acetone; Animals; Epilepsy; Humans; Ketones; Ketosis; Seizures

2004

Other Studies

12 other studies available for acetone and Aura

ArticleYear
Pharmacodynamic and pharmacokinetic interactions between common antiepileptic drugs and acetone, the chief anticonvulsant ketone body elevated in the ketogenic diet in mice.
    Epilepsia, 2009, Volume: 50, Issue:5

    Topics: Acetone; Animals; Anticonvulsants; Biophysical Phenomena; Disease Models, Animal; Dose-Response Rela

2009
Anticonvulsant activity of DNS II fraction in the acute seizure models.
    Journal of ethnopharmacology, 2010, Apr-21, Volume: 128, Issue:3

    Topics: Acetone; Animals; Anticonvulsants; Delphinium; Diazepam; Epilepsy; Male; Melanoma; Mice; Mice, Inbre

2010
Neuron-restrictive silencer factor is not required for the antiepileptic effect of the ketogenic diet.
    Epilepsia, 2011, Volume: 52, Issue:9

    Topics: Acetone; Animals; Anticonvulsants; Antimetabolites; Calcium-Calmodulin-Dependent Protein Kinase Kina

2011
Ketogenic diet: does acetone stop seizures?
    Medical science monitor : international medical journal of experimental and clinical research, 2002, Volume: 8, Issue:8

    Topics: Acetone; Animals; Anticonvulsants; Cerebrospinal Fluid; Convulsants; Diet; Epilepsy; Fasting; Humans

2002
Epilepsy and the ketogenic diet: assessment of ketosis in children using breath acetone.
    Pediatric research, 2002, Volume: 52, Issue:3

    Topics: Acetone; Anticonvulsants; Breath Tests; Child; Diet; Epilepsy; Humans; Ketone Bodies; Ketosis; Time

2002
On the anticonvulsant effect of acetone and the ketogenic diet.
    Epilepsia, 2002, Volume: 43, Issue:12

    Topics: Acetoacetates; Acetone; Animals; Anticonvulsants; Brain; Combined Modality Therapy; Dose-Response Re

2002
[Two bad girls].
    Toulouse medical, 1956, Volume: 57, Issue:10

    Topics: Acetone; Body Fluids; Child; Epilepsy; Female; Humans; Infant; Psychology, Child

1956
[Two bad girls].
    Toulouse medical, 1956, Volume: 57, Issue:10

    Topics: Acetone; Body Fluids; Child; Epilepsy; Female; Humans; Infant; Psychology, Child

1956
[Two bad girls].
    Toulouse medical, 1956, Volume: 57, Issue:10

    Topics: Acetone; Body Fluids; Child; Epilepsy; Female; Humans; Infant; Psychology, Child

1956
[Two bad girls].
    Toulouse medical, 1956, Volume: 57, Issue:10

    Topics: Acetone; Body Fluids; Child; Epilepsy; Female; Humans; Infant; Psychology, Child

1956
The anticonvulsant activity of acetone, the major ketone body in the ketogenic diet, is not dependent on its metabolites acetol, 1,2-propanediol, methylglyoxal, or pyruvic acid.
    Epilepsia, 2007, Volume: 48, Issue:4

    Topics: Acetone; Animals; Anticonvulsants; Diet Therapy; Disease Models, Animal; Epilepsy; Ketone Bodies; Ma

2007
Identification of cerebral acetone by 1H-MRS in patients with epilepsy controlled by ketogenic diet.
    Magma (New York, N.Y.), 1999, Volume: 8, Issue:1

    Topics: Acetone; Adolescent; Adult; Brain; Case-Control Studies; Child; Child, Preschool; Dietary Fats; Epil

1999
Breath acetone is a reliable indicator of ketosis in adults consuming ketogenic meals.
    The American journal of clinical nutrition, 2002, Volume: 76, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adult; Breath Tests; Diet; Dietary Fats; Epilepsy; Fa

2002
A case of anorexia.
    British medical journal, 1973, Apr-21, Volume: 2, Issue:5859

    Topics: Acetone; Adult; Amenorrhea; Anorexia Nervosa; Autopsy; Blood Pressure; Body Weight; Diet, Reducing;

1973
Ketotic hypoglycemia and the ketogenic diet.
    Neurology, 1973, Volume: 23, Issue:6

    Topics: Acetazolamide; Acetone; Acidosis; Blood Glucose; Child, Preschool; Diet Therapy; Dietary Carbohydrat

1973