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acetone and Aneuploid

acetone has been researched along with Aneuploid in 8 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

Research Excerpts

ExcerptRelevanceReference
" Several ketones (including acetone and methyl ethyl ketone) and some organic acid esters (including the methyl, ethyl and 2-methoxyethyl esters of acetic acid) and acetonitrile strongly induced aneuploidy but not recombination or point mutation."7.67Acetone, methyl ethyl ketone, ethyl acetate, acetonitrile and other polar aprotic solvents are strong inducers of aneuploidy in Saccharomyces cerevisiae. ( Mayer, VW; Resnick, MA; Scheel, I; Zimmermann, FK, 1985)
"We have shown that it induces aneuploidy in the yeast Saccharomyces cerevisiae at very low concentrations."5.27Induction of aneuploidy by oncodazole (nocodazole), an anti-tubulin agent, and acetone. ( Mayer, VW; Scheel, I; Zimmermann, FK, 1984)
"Chinese hamsters were exposed to acetone, methyl ethyl ketone, ethyl acetate and 2-methoxy ethyl acetate, known to be strong inducers of aneuploidy in the yeast Saccharomyces cerevisiae."3.67Aneuploidy-inducing chemicals in yeast evaluated by the micronucleus test. ( Basler, A, 1986)
"Nocodazole, ethyl acetate, acetone and methyl ethyl ketone all are known to induce aneuploidy."3.67Effects of chemical combinations on the induction of aneuploidy in Saccharomyces cerevisiae. ( Goin, CJ; Mayer, VW, 1987)
" Several ketones (including acetone and methyl ethyl ketone) and some organic acid esters (including the methyl, ethyl and 2-methoxyethyl esters of acetic acid) and acetonitrile strongly induced aneuploidy but not recombination or point mutation."3.67Acetone, methyl ethyl ketone, ethyl acetate, acetonitrile and other polar aprotic solvents are strong inducers of aneuploidy in Saccharomyces cerevisiae. ( Mayer, VW; Resnick, MA; Scheel, I; Zimmermann, FK, 1985)
"The state of aneuploidy test methodology was appraised by the U."1.28Reevaluation of the 9 compounds reported conclusive positive in yeast Saccharomyces cerevisiae aneuploidy test systems by the Gene-Tox Program using strain D61.M of Saccharomyces cerevisiae. ( Albertini, S, 1991)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zimmermann, FK2
Mayer, VW4
Scheel, I2
Goin, CJ2
Barbata, G1
Giglio, MC1
Granata, G1
Anzalone, A1
Carbone, P1
Albertini, S1
Basler, A1
Resnick, MA1
Fiala, ES1
Fiala, S1

Other Studies

8 other studies available for acetone and Aneuploid

ArticleYear
Induction of aneuploidy by oncodazole (nocodazole), an anti-tubulin agent, and acetone.
    Mutation research, 1984, Volume: 141, Issue:1

    Topics: Acetone; Aneuploidy; Benzimidazoles; Drug Resistance; Mutagenicity Tests; Mutagens; Nocodazole; Sacc

1984
Induction of chromosome loss in yeast by combined treatment with neurotoxic hexacarbons and monoketones.
    Mutation research, 1994, Volume: 341, Issue:2

    Topics: Acetone; Aneuploidy; Butanones; Chromosome Deletion; Drug Synergism; Hexanes; Hexanones; Methyl n-Bu

1994
Clastogenic and aneuploidizing effects of antiblastic busulphan revealed by kinetochore immunofluorescence in CHO cells.
    Mutation research, 1991, Volume: 263, Issue:4

    Topics: Acetone; Aneuploidy; Busulfan; Cell Line; Centromere; Chromosome Aberrations; Dose-Response Relation

1991
Reevaluation of the 9 compounds reported conclusive positive in yeast Saccharomyces cerevisiae aneuploidy test systems by the Gene-Tox Program using strain D61.M of Saccharomyces cerevisiae.
    Mutation research, 1991, Volume: 260, Issue:2

    Topics: Acetone; Aneuploidy; Benomyl; Benzimidazoles; Biotransformation; Carbamates; Chromosomes, Fungal; Cy

1991
Aneuploidy-inducing chemicals in yeast evaluated by the micronucleus test.
    Mutation research, 1986, Volume: 174, Issue:1

    Topics: Acetates; Acetone; Aneuploidy; Animals; Butanones; Cell Nucleus; Cricetinae; Female; Male; Mutagenic

1986
Effects of chemical combinations on the induction of aneuploidy in Saccharomyces cerevisiae.
    Mutation research, 1987, Volume: 187, Issue:1

    Topics: Acetates; Acetone; Aneuploidy; Benzimidazoles; Butanones; Carbamates; Dimethyl Sulfoxide; Dimethylfo

1987
Acetone, methyl ethyl ketone, ethyl acetate, acetonitrile and other polar aprotic solvents are strong inducers of aneuploidy in Saccharomyces cerevisiae.
    Mutation research, 1985, Volume: 149, Issue:3

    Topics: Acetates; Acetone; Acetonitriles; Aneuploidy; Butanones; Mitosis; Saccharomyces cerevisiae; Solvents

1985
Inactivation of thymidylate kinase by a microsomal factor.
    Biochimica et biophysica acta, 1970, Apr-15, Volume: 204, Issue:2

    Topics: Acetone; Aminohydrolases; Aneuploidy; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatogr

1970