Page last updated: 2024-10-16

acetone and Alloxan Diabetes

acetone has been researched along with Alloxan Diabetes in 27 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

Research Excerpts

ExcerptRelevanceReference
"Drug Gliclazide (Glz) has limited solubility and low bioavailability."1.42Controlled release of anti-diabetic drug Gliclazide from poly(caprolactone)/poly(acrylic acid) hydrogels. ( Bajpai, SK; Chand, N; Soni, S, 2015)
"Glycerol was the best substrate for D-lactate formation via methylglyoxal in rat liver."1.29Carbon sources for D-lactate formation in rat liver. ( Hirata, M; Kawase, M; Kondoh, Y; Ohmori, S, 1994)
"2."1.28Induction of rat hepatic mixed-function oxidases by acetone and other physiological ketones: their role in diabetes-induced changes in cytochrome P450 proteins. ( Barnett, CR; Flatt, PR; Ioannides, C; Petrides, L; Wilson, J, 1992)
" However, a dose-response experiment showed endogenous levels of acetone to be capable of causing at most 40% of the induction in fasted rats."1.27Studies on the mechanisms of induction of N-nitrosodimethylamine demethylase by fasting, acetone, and ethanol. ( Miller, KW; Yang, CS, 1984)
"Pretreatment with acetone or isopropanol (2."1.27Potentiation of the hepatotoxicity of N-nitrosodimethylamine by fasting, diabetes, acetone, and isopropanol. ( Chung, HR; Lorr, NA; Miller, KW; Yang, CS, 1984)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199014 (51.85)18.7374
1990's6 (22.22)18.2507
2000's1 (3.70)29.6817
2010's6 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mohammed, A2
Islam, MS3
Imam-Fulani, AO1
Sanusi, KO1
Owoyele, BV1
Ibrahim, MA1
Bajpai, SK1
Chand, N1
Soni, S1
Koorbanally, NA1
Yamai, K1
Funada, T1
Ohkuwa, T1
Itoh, H1
Tsuda, T1
MOURKIDES, GA1
HOBBS, DC1
KOEPPE, RE1
MARUHAMA, Y1
Sy, GY1
Cissé, A1
Nongonierma, RB1
Sarr, M1
Mbodj, NA1
Faye, B1
Miller, KW2
Yang, CS2
Lorr, NA1
Chung, HR1
Coleman, DL1
Kondoh, Y1
Kawase, M1
Hirata, M1
Ohmori, S1
Kalapos, MP2
Riba, P1
Garzo, T1
Mandl, J1
Ghafghazi, T1
Sheriat, HS1
Dastmalchi, T1
Barnett, RC1
Barnett, CR1
Petrides, L1
Wilson, J1
Flatt, PR1
Ioannides, C1
Valentovic, M1
Ball, JG1
Anestis, D1
Jeffery, EH1
Arndt, K1
Haschek, WM1
Kosugi, K1
Scofield, RF1
Chandramouli, V1
Kumaran, K1
Schumann, WC1
Landau, BR1
Hetenyi, G1
Byers, M1
Ferrarotto, C1
Toyota, T1
Goto, Y1
Sato, S1
Shimojo, Y1
Takahashi, K1
Wieland, O1
Ziboh, VA1
Rauls, TJ1
Hsia, SL1
Frohlich, A1
Dzialoszynski, LM1
Shafrir, E1
Gutman, A1
Gorin, E1
Orevi, M1
Bunnag, SC1
Warner, NE1
Bunnag, S1

Reviews

3 reviews available for acetone and Alloxan Diabetes

ArticleYear
[Acetone metabolism: biochemistry, toxicology and clinical implications].
    Orvosi hetilap, 1997, May-11, Volume: 138, Issue:19

    Topics: 1-Propanol; Acetone; Alcoholism; Animals; Cytochrome P-450 Enzyme System; Diabetes Mellitus; Diabete

1997
Ketogenesis and its regulation.
    Advances in metabolic disorders, 1968, Volume: 3

    Topics: Acetoacetates; Acetone; Adenine Nucleotides; Adult; Animals; Cattle; Child; Citric Acid Cycle; Diabe

1968
Regulatory aspects in carbohydrate metabolism of adipose tissue: glycolysis, glycogen synthesis, and glyceroneogenesis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1970, Volume: 2

    Topics: Acetone; Adipose Tissue; Amino Acids; Animals; Diabetes Mellitus, Experimental; Epididymis; Fasting;

1970

Other Studies

24 other studies available for acetone and Alloxan Diabetes

ArticleYear
Antioxidant potential of Xylopia aethiopica fruit acetone fraction in a type 2 diabetes model of rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 96

    Topics: Acetone; Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Free Rad

2017
Effects of acetone extract of Cola nitida on brain sodium-potassium adenosine triphosphatase activity and spatial memory in healthy and streptozotocin-induced diabetic female Wistar rats.
    Journal of basic and clinical physiology and pharmacology, 2018, Jul-26, Volume: 29, Issue:4

    Topics: Acetone; Animals; Brain; Cola; Diabetes Mellitus, Experimental; Female; Plant Extracts; Rats; Rats,

2018
Anti-diabetic effects of the acetone fraction of Senna singueana stem bark in a type 2 diabetes rat model.
    Journal of ethnopharmacology, 2014, Apr-28, Volume: 153, Issue:2

    Topics: Acetone; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoglycemic Agents; M

2014
Controlled release of anti-diabetic drug Gliclazide from poly(caprolactone)/poly(acrylic acid) hydrogels.
    Journal of biomaterials science. Polymer edition, 2015, Volume: 26, Issue:14

    Topics: Acetone; Acrylamides; Acrylates; Acrylic Resins; Animals; Caproates; Delayed-Action Preparations; Di

2015
Anti-diabetic effect of Xylopia aethiopica (Dunal) A. Rich. (Annonaceae) fruit acetone fraction in a type 2 diabetes model of rats.
    Journal of ethnopharmacology, 2016, Mar-02, Volume: 180

    Topics: Acetone; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fruit;

2016
Acetone concentration in gas emanating from tails of diabetic rats.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2012, Volume: 28, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Gases; Male

2012
The metabolism of acetone-2-C14 by intact rats.
    The Journal of biological chemistry, 1959, Volume: 234, Issue:1

    Topics: Acetone; Animals; Diabetes Mellitus, Experimental; Fasting; Rats

1959
DIET AND BLOOD LIPIDS IN NORMAL AND DIABETIC RATS.
    Metabolism: clinical and experimental, 1965, Volume: 14

    Topics: Acetone; Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Diet; Di

1965
Hypoglycaemic and antidiabetic activity of acetonic extract of Vernonia colorata leaves in normoglycaemic and alloxan-induced diabetic rats.
    Journal of ethnopharmacology, 2005, Apr-08, Volume: 98, Issue:1-2

    Topics: Acetone; Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Mode

2005
Studies on the mechanisms of induction of N-nitrosodimethylamine demethylase by fasting, acetone, and ethanol.
    Archives of biochemistry and biophysics, 1984, Volume: 229, Issue:2

    Topics: Acetone; Animals; Cytochrome P-450 CYP2E1; Diabetes Mellitus, Experimental; Enzyme Induction; Ethano

1984
Potentiation of the hepatotoxicity of N-nitrosodimethylamine by fasting, diabetes, acetone, and isopropanol.
    Toxicology and applied pharmacology, 1984, Volume: 73, Issue:3

    Topics: 1-Propanol; Acetone; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytoc

1984
Acetone metabolism in mice: increased activity in mice heterozygous for obesity genes.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:1

    Topics: Acetone; Animals; Diabetes Mellitus, Experimental; Gluconeogenesis; Heterozygote; Kidney; Lactates;

1980
Carbon sources for D-lactate formation in rat liver.
    Journal of biochemistry, 1994, Volume: 115, Issue:3

    Topics: Acetoacetates; Acetone; Animals; Diabetes Mellitus, Experimental; Glucose; Glycerol; In Vitro Techni

1994
Glucose formation from methylglyoxal in hepatocytes from streptozotocin-induced diabetic mice: the effect of insulin.
    Experientia, 1996, Aug-15, Volume: 52, Issue:8

    Topics: Acetone; Aminophenols; Aniline Compounds; Animals; Cells, Cultured; Diabetes Mellitus, Experimental;

1996
Antagonism of cadmium and alloxan-induced hyperglycemia in rats by Trigonella foenum graecum.
    Pahlavi medical journal, 1977, Volume: 8, Issue:1

    Topics: Acetone; Alloxan; Animals; Cadmium; Diabetes Mellitus, Experimental; Hyperglycemia; Hypoglycemic Age

1977
Induction of rat hepatic mixed-function oxidases by acetone and other physiological ketones: their role in diabetes-induced changes in cytochrome P450 proteins.
    Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:12

    Topics: Acetone; Animals; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Enzyme Induction;

1992
Contribution of acetone and osmotic-diuresis by streptozotocin-induced diabetes in attenuation of cephaloridine nephrotoxicity.
    Toxicology, 1992, Volume: 71, Issue:3

    Topics: Acetone; Animals; Blood Glucose; Blood Urea Nitrogen; Body Weight; Cephaloridine; Diabetes Mellitus,

1992
The role of cytochrome P450IIE1 in bioactivation of acetaminophen in diabetic and acetone-treated mice.
    Advances in experimental medicine and biology, 1991, Volume: 283

    Topics: Acetaminophen; Acetone; Animals; Biotransformation; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme

1991
Pathways of acetone's metabolism in the rat.
    The Journal of biological chemistry, 1986, Mar-25, Volume: 261, Issue:9

    Topics: Acetone; Acetyl Coenzyme A; Animals; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Female;

1986
Gluconeogenesis from acetone in diabetic rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1987, Volume: 19, Issue:4

    Topics: Acetone; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Gluconeogenesis; Lactates; Male; M

1987
Maltose metabolism in diabetic state.
    The Tohoku journal of experimental medicine, 1974, Volume: 114, Issue:1

    Topics: Acetone; Adolescent; Adult; Animals; Blood Glucose; Child; Diabetes Mellitus; Diabetes Mellitus, Exp

1974
Adaptive changes of glycerol 3-phosphate dehydrogenase level in rat skin: effects of starvation, alloxan diabetes and insulin.
    Endocrinology, 1971, Volume: 89, Issue:1

    Topics: Acetone; Animals; Dactinomycin; Diabetes Mellitus, Experimental; Drug Antagonism; Enzyme Induction;

1971
Insulin dependence of milk formation and lactose biosynthesis.
    Clinica chimica acta; international journal of clinical chemistry, 1973, Aug-17, Volume: 47, Issue:1

    Topics: Acetone; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucose; Glycosuria; Insul

1973
Effect of alloxan on the mouse pancreas during and after recovery from diabetes.
    Diabetes, 1967, Volume: 16, Issue:2

    Topics: Acetone; Alloxan; Animals; Autoradiography; Blood Glucose; Diabetes Mellitus, Experimental; Female;

1967