Page last updated: 2024-09-29

acetone and Allergic Encephalomyelitis

acetone has been researched along with Allergic Encephalomyelitis in 2 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Levine, S1
Wenk, EJ1
Devlin, HB1
Pieroni, RE1
Levine, L1
Uyemura, K1
Tobari, C1
Hirano, S1

Other Studies

2 other study(ies) available for acetone and Allergic Encephalomyelitis

ArticleYear
Hyperacute allergic encephalomyelitis: adjuvant effect of pertussis vaccines and extracts.
    Journal of immunology (Baltimore, Md. : 1950), 1966, Volume: 97, Issue:3

    Topics: Acetone; Adjuvants, Immunologic; Animals; Bacterial Vaccines; Encephalomyelitis, Autoimmune, Experimental; Endotoxins; Escherichia coli; Hot Temperature; Pertussis Vaccine; Rats; Salmonella typhi; Spinal Cord

1966
Purifications and properties of basic proteins in pig spinal cord and peripheral nerve.
    Biochimica et biophysica acta, 1970, Jul-27, Volume: 214, Issue:1

    Topics: Acetone; Amino Acids; Animals; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Disc; Encephalomyelitis, Autoimmune, Experimental; Hydrochloric Acid; Hydrogen-Ion Concentration; Muramidase; Nerve Tissue Proteins; Peripheral Nerves; Sodium Chloride; Spectrophotometry; Spinal Cord; Swine; Ultracentrifugation; Ultraviolet Rays

1970