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acetone and Alcoholism

acetone has been researched along with Alcoholism in 40 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)

Research Excerpts

ExcerptRelevanceReference
"Acetone levels were significantly higher in the acutely intoxicated subjects than in the normals (p less than 0."5.28Elevated concentrations of acetone and unidentified compounds in the breath of alcohol abusers. ( Greenberg, J; Martinez, V; Phillips, M, 1989)
"Data from 191 post-mortem cases where post-mortem blood beta-hydroxybutyrate (βHB) and acetone concentrations and vitreous humor glucose concentrations (where available) had been measured were retrospectively investigated to determine the markers required to identify and distinguish between Alcoholic Ketoacidosis (AKA), Diabetic Ketoacidosis (DKA) and Hyperosmolar Hyperglycemic State (HHS)."3.78Investigation of markers to indicate and distinguish death due to alcoholic ketoacidosis, diabetic ketoacidosis and hyperosmolar hyperglycemic state using post-mortem samples. ( Andrews, R; Dhillo, W; Hockenhull, J; Paterson, S, 2012)
"To evaluate the ability of a hand-held breath analyser, the Zenalyser((R)) (Zenics Medical), to identify alcohol-dependent patients receiving disulfiram therapy and to assess the sensitivity and specificity of the instrument at different time intervals post-disulfiram dosing."3.73A breath test to assess compliance with disulfiram. ( Chick, J; Faulder, GC; Faulder, RM; Fletcher, K; Jones, K; Kelly, M; Mohamad, MW; Morgan, D; Stone, E; Wegerdt, J, 2006)
"Ethanol, acetone, diet and starvation, known modulators of the hepatic cytochrome P450 (CYP)-dependent microsomal monooxygenase system, were assessed for their effects on cytochrome P450 isozyme content and monooxygenase activities in the male rat kidney."3.70Expression and distribution of cytochrome P450 enzymes in male rat kidney: effects of ethanol, acetone and dietary conditions. ( Badger, TM; Huang, J; Ingelman-Sundberg, M; Longo, V; Ronis, MJ; Tindberg, N, 1998)
" In a first series, acetone was determined in the blood of such chronic alcoholics (n = 24), diabetics with metabolic decompensation (n = 7), cases of hypothermia (n = 7) and controls (n = 218)."3.70Ketoacidosis and lactic acidosis--frequent causes of death in chronic alcoholics? ( Brinkmann, B; DuChesne, A; Fechner, G; Karger, B, 1998)
"Fetal ketoacidosis with hypoxic-ischemic brain damage was determined to be the cause of death."1.48Detection of elevated ketone bodies by postmortem 1H-MRS in a case of fetal ketoacidosis. ( Fliss, B; Gascho, D; Heimer, J; Martinez, RM; Zoelch, N, 2018)
"Diabetes and alcohol abuse may cause severe metabolic disturbances that can be fatal."1.39Assessment of Traub formula and ketone bodies in cause of death investigations. ( Keltanen, T; Lindroos, K; Palo, JU; Partanen, T; Sajantila, A; Valonen, T, 2013)
"Alcohol ketoacidosis is a frequently missed diagnosis, but is well described in the literature."1.39Ketoacidosis and trace amounts of isopropanol in a chronic alcoholic patient. ( Dwyer, JB; Tamama, K, 2013)
"The data showed that ketoacidosis can occur without a history of alcoholism or diabetes."1.38Investigation of markers to indicate and distinguish death due to alcoholic ketoacidosis, diabetic ketoacidosis and hyperosmolar hyperglycemic state using post-mortem samples. ( Andrews, R; Dhillo, W; Hockenhull, J; Paterson, S, 2012)
"Acetone treatment alone induced CYP2E1-dependent p-nitrophenol hydroxylase activity in kidney microsomes by 8-fold."1.30Expression and distribution of cytochrome P450 enzymes in male rat kidney: effects of ethanol, acetone and dietary conditions. ( Badger, TM; Huang, J; Ingelman-Sundberg, M; Longo, V; Ronis, MJ; Tindberg, N, 1998)
"Other causes of a ketoacidosis or lactic acidosis (e."1.30Ketoacidosis and lactic acidosis--frequent causes of death in chronic alcoholics? ( Brinkmann, B; DuChesne, A; Fechner, G; Karger, B, 1998)
"Forensic pathologists are familiar with alcohol abusers, who are found dead and in whom the cause of death cannot be ascertained."1.29Alcoholic ketoacidosis as a cause of death in forensic cases. ( Felby, S; Nielsen, E; Theilade, P; Thomsen, JL, 1995)
"Acetone levels were significantly higher in the acutely intoxicated subjects than in the normals (p less than 0."1.28Elevated concentrations of acetone and unidentified compounds in the breath of alcohol abusers. ( Greenberg, J; Martinez, V; Phillips, M, 1989)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199011 (27.50)18.7374
1990's15 (37.50)18.2507
2000's8 (20.00)29.6817
2010's6 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Heimer, J1
Gascho, D1
Fliss, B1
Martinez, RM1
Zoelch, N1
Fenves, AZ1
Mojtahed, A1
Nisavic, M1
Massoth, LR1
Keltanen, T1
Sajantila, A1
Palo, JU1
Partanen, T1
Valonen, T1
Lindroos, K1
Gomółka, E1
Radomska, M1
Sulka, A1
Molina, DK1
Hockenhull, J1
Dhillo, W1
Andrews, R1
Paterson, S1
Dwyer, JB1
Tamama, K1
Kostusiak, V1
Bekkal, R1
Mateu, P1
Kalapos, MP2
Jones, AW1
Holmgren, P1
Fletcher, K1
Stone, E1
Mohamad, MW1
Faulder, GC1
Faulder, RM1
Jones, K1
Morgan, D1
Wegerdt, J1
Kelly, M1
Chick, J1
Alexander, CB1
McBay, AJ1
Hudson, RP1
Roberts, BJ1
Shoaf, SE1
Jeong, KS1
Song, BJ1
Davin, A1
Vion-Dury, J1
Viout, P1
Cozzone, PJ1
Iffland, R3
Balling, MP1
Börsch, G1
Herold, C1
Kaschade, W1
Löffler, T1
Schmidtmann, U2
Stettner, J1
Thomsen, JL2
Theilade, P2
Felby, S2
Nielsen, E2
Osterloh, JD1
Kelly, TJ1
Khayam-Bashi, H1
Romeo, R1
Wiernikowski, A1
Piekoszewski, W2
Krzyzanowska-Kierepka, E1
Gomułka, E1
Ronis, MJ1
Huang, J1
Longo, V1
Tindberg, N1
Ingelman-Sundberg, M1
Badger, TM1
Brinkmann, B3
Fechner, G1
Karger, B1
DuChesne, A1
Pounder, DJ1
Stevenson, RJ1
Taylor, KK1
Köhler, H2
Banaschak, S1
Berg, A1
Eikelmann, B1
West, A1
Heinecke, A2
Beike, J1
Bajanowski, T1
Zuba, D1
Pach, J1
Winnik, L1
Parczewski, A1
Crato, H1
Walther, G1
Herrmann, A1
Ninfali, P1
Rossi, L1
Baronciani, L1
Tirillini, B1
Ropars, C1
Magnani, M1
Barz, J1
Bonte, W1
Keultjes, C1
Sieland, J1
Lucas, D1
Berthou, F1
Dreano, Y1
Floch, HH1
Menez, JF1
Phillips, M1
Greenberg, J1
Martinez, V1
Schmidt, V1
Oehmichen, M1
Norpoth, T1
Lester, D2
Freed, EX2
Fried, R1
Masoud, AN1
Klein, FM1
Beigelman, PM1
Majchrowicz, E1
Mendelson, JH1
Freund, G1
O'Hollaren, P1
Baker, RN1
Alenty, AL1
Zack, JF1

Reviews

3 reviews available for acetone and Alcoholism

ArticleYear
On the mammalian acetone metabolism: from chemistry to clinical implications.
    Biochimica et biophysica acta, 2003, May-02, Volume: 1621, Issue:2

    Topics: 2-Propanol; Acetoacetates; Acetone; Alcoholism; Carbon Dioxide; Diabetes Mellitus; Glucose; Humans;

2003
[Acetone metabolism: biochemistry, toxicology and clinical implications].
    Orvosi hetilap, 1997, May-11, Volume: 138, Issue:19

    Topics: 1-Propanol; Acetone; Alcoholism; Animals; Cytochrome P-450 Enzyme System; Diabetes Mellitus; Diabete

1997
Severe diabetic ketoacidosis (diabetic "coma"). 482 episodes in 257 patients; experience of three years.
    Diabetes, 1971, Volume: 20, Issue:7

    Topics: Acetone; Adolescent; Adult; Age Factors; Aged; Alcoholism; Amylases; Blood Glucose; Blood Urea Nitro

1971

Trials

2 trials available for acetone and Alcoholism

ArticleYear
Incidence of alcohol dependence among drunken drivers.
    Drug and alcohol dependence, 2002, Mar-01, Volume: 66, Issue:1

    Topics: 2-Propanol; Acetone; Adolescent; Adult; Age Factors; Alcoholic Intoxication; Alcoholism; Automobile

2002
Acetaldehyde concentrations in alveolar air following a standard dose of ethanol in man.
    Journal of lipid research, 1965, Volume: 6, Issue:4

    Topics: Acetaldehyde; Acetone; Adult; Air; Alcoholism; Blood Chemical Analysis; Body Weight; Brain Damage, C

1965

Other Studies

35 other studies available for acetone and Alcoholism

ArticleYear
Detection of elevated ketone bodies by postmortem 1H-MRS in a case of fetal ketoacidosis.
    Journal of forensic and legal medicine, 2018, Volume: 59

    Topics: 3-Hydroxybutyric Acid; Acetone; Acidosis, Lactic; Alcoholism; Cerebrum; Fasting; Female; Fetal Blood

2018
Case 13-2019: A 54-Year-Old Man with Alcohol Withdrawal and Altered Mental Status.
    The New England journal of medicine, 2019, Apr-25, Volume: 380, Issue:17

    Topics: 2-Propanol; Acetone; Acid-Base Equilibrium; Acidosis; Alcohol Withdrawal Delirium; Alcoholism; Diagn

2019
Assessment of Traub formula and ketone bodies in cause of death investigations.
    International journal of legal medicine, 2013, Volume: 127, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Alcoholism; Algorithms; Autopsy; Biomarkers; Blood Gl

2013
[Tobacco smoking by patients treat for alcohol addiction--interaction of psychoactive substances].
    Przeglad lekarski, 2009, Volume: 66, Issue:10

    Topics: Acetaldehyde; Acetone; Adult; Alcoholism; Cotinine; Drug Interactions; Female; Humans; Male; Methano

2009
A characterization of sources of isopropanol detected on postmortem toxicologic analysis.
    Journal of forensic sciences, 2010, Volume: 55, Issue:4

    Topics: 2-Propanol; Acetone; Alcoholism; Coroners and Medical Examiners; Dehydration; Diabetes Mellitus; Emb

2010
Investigation of markers to indicate and distinguish death due to alcoholic ketoacidosis, diabetic ketoacidosis and hyperosmolar hyperglycemic state using post-mortem samples.
    Forensic science international, 2012, Jan-10, Volume: 214, Issue:1-3

    Topics: 3-Hydroxybutyric Acid; Acetone; Adult; Aged; Alcoholism; Biomarkers; Diabetic Ketoacidosis; Female;

2012
Ketoacidosis and trace amounts of isopropanol in a chronic alcoholic patient.
    Clinica chimica acta; international journal of clinical chemistry, 2013, Jan-16, Volume: 415

    Topics: 2-Propanol; 3-Hydroxybutyric Acid; Acetone; Adult; Alcoholism; Blood Glucose; Chronic Disease; Human

2013
Survival after drinking lethal dose of acetone.
    Intensive care medicine, 2003, Volume: 29, Issue:2

    Topics: Acetone; Alcoholism; Critical Care; Female; Humans; Middle Aged; Poisoning; Suicide, Attempted; Surv

2003
Comparison of blood-ethanol concentration in deaths attributed to acute alcohol poisoning and chronic alcoholism.
    Journal of forensic sciences, 2003, Volume: 48, Issue:4

    Topics: 2-Propanol; Acetone; Alcoholism; Databases, Factual; Ethanol; Female; Forensic Medicine; Humans; Mal

2003
A breath test to assess compliance with disulfiram.
    Addiction (Abingdon, England), 2006, Volume: 101, Issue:12

    Topics: Acetone; Alcohol Deterrents; Alcoholism; Breath Tests; Carbon Disulfide; Disulfiram; Humans; Patient

2006
Isopropanol and isopropanol deaths-ten years' experience.
    Journal of forensic sciences, 1982, Volume: 27, Issue:3

    Topics: 1-Propanol; Acetone; Adult; Aged; Alcoholism; Autopsy; Female; Humans; Male; Middle Aged

1982
Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half-life of 6 hours or less.
    Biochemical and biophysical research communications, 1994, Dec-15, Volume: 205, Issue:2

    Topics: Acetone; Activity Cycles; Alcoholism; Animals; Blotting, Northern; Brain; Cytochrome P-450 CYP2E1; C

1994
Rapid evaluation of ethanol content and metabolism in human plasma using quantitative proton magnetic resonance spectroscopy.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1994, Volume: 29, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetates; Acetone; Alcohol Drinking; Alcoholism; Biomarkers; Ethanol; Humans;

1994
[Evaluation of an increased blood level of GGT, CDT, methanol, acetone and isopropanol in alcohol intoxicated automobile drivers. Alcoholism indicators instead of medical-psychological examination].
    Blutalkohol, 1994, Volume: 31, Issue:5

    Topics: 1-Propanol; Acetone; Adolescent; Adult; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Automo

1994
Alcoholism and ketoacidosis.
    Forensic science international, 1993, Volume: 60, Issue:1-2

    Topics: Acetoacetates; Acetone; Alcoholism; Butyrates; Cause of Death; Forensic Medicine; Humans; Ketone Bod

1993
Alcoholic ketoacidosis as a cause of death in forensic cases.
    Forensic science international, 1995, Oct-30, Volume: 75, Issue:2-3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Alcoholis

1995
Discrepancies in osmolal gaps and calculated alcohol concentrations.
    Archives of pathology & laboratory medicine, 1996, Volume: 120, Issue:7

    Topics: 1-Propanol; Acetone; Adult; Alcoholism; Blood Chemical Analysis; Chromatography; Ethanol; Humans; Li

1996
New ways to use biochemical indicators of alcohol abuse to regrant licences in a fairer manner after drunken driving in Germany.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1996, Volume: 31, Issue:6

    Topics: 1-Propanol; Acetone; Alcoholism; Automobile Driving; Biomarkers; Ethanol; gamma-Glutamyltransferase;

1996
[Acute oral poisoning with isopropyl alcohol in alcoholics].
    Przeglad lekarski, 1997, Volume: 54, Issue:6

    Topics: 1-Propanol; Acetone; Adult; Alcoholism; Diagnosis, Differential; Ethanol; Half-Life; Humans; Male

1997
Expression and distribution of cytochrome P450 enzymes in male rat kidney: effects of ethanol, acetone and dietary conditions.
    Biochemical pharmacology, 1998, Jan-15, Volume: 55, Issue:2

    Topics: Acetone; Alcoholism; Animals; Apoenzymes; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2E1; Cy

1998
Ketoacidosis and lactic acidosis--frequent causes of death in chronic alcoholics?
    International journal of legal medicine, 1998, Volume: 111, Issue:3

    Topics: Acetone; Acidosis, Lactic; Adult; Alcoholic Intoxication; Alcoholism; Autopsy; Cause of Death; Diabe

1998
Alcoholic ketoacidosis at autopsy.
    Journal of forensic sciences, 1998, Volume: 43, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Alcoholis

1998
ROC analysis of alcoholism markers--100% specificity.
    International journal of legal medicine, 2000, Volume: 113, Issue:5

    Topics: 1-Propanol; Acetone; Adult; Aged; Alcoholism; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female;

2000
Concentration of ethanol and other volatile compounds in the blood of acutely poisoned alcoholics.
    Alcohol (Fayetteville, N.Y.), 2002, Volume: 26, Issue:1

    Topics: 1-Propanol; 2-Propanol; Acetaldehyde; Acetone; Adolescent; Adult; Aged; Alcoholic Intoxication; Alco

2002
[The occurrence of acetone in blood samples forwarded for alcohol content analysis].
    Beitrage zur gerichtlichen Medizin, 1978, Volume: 36

    Topics: Acetone; Alcoholism; Ethanol; Female; Gluconeogenesis; Humans; Male

1978
Acetaldehyde, ethanol and acetone concentrations in blood of alcohol-treated mice receiving aldehyde dehydrogenase-loaded erythrocytes.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1992, Volume: 27, Issue:1

    Topics: Acetaldehyde; Acetone; Alcoholism; Aldehyde Dehydrogenase; Animals; Blood Component Transfusion; Ery

1992
Concentrations of ethanol, methanol, propanol-2 and acetone in blood samples of impaired drivers.
    Acta medicinae legalis et socialis, 1990, Volume: 40

    Topics: 1-Propanol; Acetone; Alcoholic Intoxication; Alcoholism; Automobile Driving; Biomarkers; Ethanol; Hu

1990
Ethanol-inducible cytochrome P-450: assessment of substrates' specific chemical probes in rat liver microsomes.
    Alcoholism, clinical and experimental research, 1990, Volume: 14, Issue:4

    Topics: Acetone; Alcoholism; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Isoenzymes;

1990
Elevated concentrations of acetone and unidentified compounds in the breath of alcohol abusers.
    Alcoholism, clinical and experimental research, 1989, Volume: 13, Issue:4

    Topics: Acetone; Adult; Alcoholic Intoxication; Alcoholism; Breath Tests; Ethanol; Female; Follow-Up Studies

1989
[Acetone and isopropanol concentration of blood in relation to acute and chronic alcoholism].
    Blutalkohol, 1988, Volume: 25, Issue:2

    Topics: 1-Propanol; Acetone; Adolescent; Adult; Alcoholic Intoxication; Alcoholism; Ethanol; Female; Humans;

1988
A rat model of alcoholism?
    Annals of the New York Academy of Sciences, 1972, May-25, Volume: 197

    Topics: Acetone; Alcohol Drinking; Alcoholism; Animal Nutritional Physiological Phenomena; Animals; Conditio

1972
Colorimetric assay of disulfiram.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:8

    Topics: Absorption; Acetone; Alcoholism; Colorimetry; Disulfiram; Humans; Solutions; Solvents; Spectrophotom

1973
Blood methanol concentrations during experimentally induced ethanol intoxication in alcoholics.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:2

    Topics: Acetaldehyde; Acetone; Adult; Alcoholic Beverages; Alcoholic Intoxication; Alcoholism; Chromatograph

1971
Schedule-induced consumption of ethanol: calories or chemotherapy?
    Physiology & behavior, 1970, Volume: 5, Issue:5

    Topics: Acetone; Alcohol Drinking; Alcoholism; Animal Nutritional Physiological Phenomena; Animals; Behavior

1970
Toxic volatiles in alcoholic coma. A report of simultaneous determination of blood methanol, ethanol, isopropanol, acetaldehyde and acetone by gas chromatography.
    Bulletin of the Los Angeles neurological societies, 1968, Volume: 33, Issue:3

    Topics: 1-Propanol; Acetaldehyde; Acetone; Alcoholism; Chromatography, Gas; Coma; Ethanol; Humans; Methanol;

1968