acetone and Aging
acetone has been researched along with Aging in 26 studies
methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to determine how aging affects the induction by ethanol or acetone of the hepatic microsomal monooxygenase system of female Fischer 344 rats." | 3.67 | Effects of ethanol on microsomal drug metabolism in aging female rats. I. Induction. ( Rikans, LE, 1989) |
| "1) was increased several-fold on aging of microsomes, on delipidation by extraction with acetone or on solubilization with deoxycholate, suggesting its existence in a cryptic state." | 3.65 | The cryptic nature of hepatic microsomal sulphite oxidase. ( Joshi, VC; Kurup, CK; Ramasarma, T, 1969) |
| "Acetone treatment was used to perturb the skin barrier." | 1.31 | The skin barrier state of aged hairless mice in a dry environment. ( Ahn, SK; Chang, I; Choi, EH; Kim, MJ; Lee, SH; Nam, GW; Park, WS; Son, ED, 2002) |
| "Acetone was found to be the best of 5 solvents used to extract the tick-repellent substance." | 1.29 | Repellence of the tick Rhipicephalus appendiculatus by the grass Melinis minutiflora. ( Essuman, S; Kaaya, GP; Kimondo, MG; Munyinyi, D; Mwangi, EN; Nyandat, E, 1995) |
| "GSHt contents in squamous cell carcinomas (SCC) were twice the values measured in papillomas and 5- to 8-fold greater than the values measured in non-treated skins, and the non-tumorous tissue adjacent to SCC." | 1.28 | Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part II: Quantitation of glutathione and glutathione disulfide. ( Cappel, RE; Gilbert, HF; Kodari, E; Reiners, JJ, 1991) |
Research
Studies (26)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (46.15) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Millecamps, M | 1 |
| Shi, XQ | 1 |
| Piltonen, M | 1 |
| Echeverry, S | 1 |
| Diatchenko, L | 1 |
| Zhang, J | 1 |
| Stone, LS | 1 |
| Freemantle, E | 1 |
| Vandal, M | 1 |
| Tremblay Mercier, J | 1 |
| Plourde, M | 1 |
| Poirier, J | 1 |
| Cunnane, SC | 1 |
| Choi, EH | 1 |
| Kim, MJ | 1 |
| Ahn, SK | 1 |
| Park, WS | 1 |
| Son, ED | 1 |
| Nam, GW | 1 |
| Chang, I | 1 |
| Lee, SH | 1 |
| Guo, X | 1 |
| Dixit, V | 1 |
| Liu, H | 1 |
| Shroads, AL | 1 |
| Henderson, GN | 1 |
| James, MO | 1 |
| Stacpoole, PW | 1 |
| Turner, C | 1 |
| Spanel, P | 1 |
| Smith, D | 1 |
| Kalapos, MP | 1 |
| Marks, F | 1 |
| Fürstenberger, G | 1 |
| Klinger, W | 2 |
| Sommer, M | 1 |
| Glöckner, R | 1 |
| Saghir, SA | 1 |
| Hansen, LG | 1 |
| Odeigah, PG | 1 |
| Deyl, Z | 1 |
| Miksík, I | 1 |
| Mwangi, EN | 1 |
| Essuman, S | 1 |
| Kaaya, GP | 1 |
| Nyandat, E | 1 |
| Munyinyi, D | 1 |
| Kimondo, MG | 1 |
| Nelson, N | 1 |
| Lagesson, V | 1 |
| Nosratabadi, AR | 1 |
| Ludvigsson, J | 1 |
| Tagesson, C | 1 |
| Niewmierzycka, A | 1 |
| Clarke, S | 1 |
| Laska, M | 1 |
| Gemant, A | 1 |
| Bluzat, R | 1 |
| Jonot, O | 1 |
| Lespinasse, G | 1 |
| Seugé, J | 1 |
| Reiners, JJ | 1 |
| Kodari, E | 1 |
| Cappel, RE | 1 |
| Gilbert, HF | 1 |
| Rikans, LE | 1 |
| Ward, JM | 1 |
| Quander, R | 1 |
| Devor, D | 1 |
| Wenk, ML | 1 |
| Spangler, EF | 1 |
| Hollenberg, CH | 1 |
| Vost, A | 1 |
| Woods, JS | 1 |
| Dixon, RL | 1 |
| Ongun, A | 1 |
| Mudd, JB | 1 |
| Joshi, VC | 1 |
| Kurup, CK | 1 |
| Ramasarma, T | 1 |
| Hird, FJ | 1 |
| Weidemann, MJ | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacotoxicology of Trichloroethylene Metabolites: Short-term Effect of DCA on in Vivo Tyrosine Catabolism and MAAI Expression[NCT00865514] | 2 participants (Actual) | Interventional | 2011-08-31 | Terminated (stopped due to Difficulty in obtaining the solution from the compounding pharmacies caused a two year delay in start-up; the funding ended prior to study completion.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trials
1 trial available for acetone and Aging
| Article | Year |
|---|---|
Metabolic response to a ketogenic breakfast in the healthy elderly.
Topics: 3-Hydroxybutyric Acid; Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Apolipoprotein E4 | 2009 |
Other Studies
25 other studies available for acetone and Aging
| Article | Year |
|---|---|
The geriatric pain experience in mice: intact cutaneous thresholds but altered responses to tonic and chronic pain.
Topics: Acetone; Aging; Animals; Behavior; Biogenic Monoamines; Capsaicin; Chronic Pain; Disease Models, Ani | 2020 |
The skin barrier state of aged hairless mice in a dry environment.
Topics: Acetone; Aging; Animals; Environment; Epidermis; Lipid Metabolism; Mice; Mice, Nude; Microscopy, Ele | 2002 |
Inhibition and recovery of rat hepatic glutathione S-transferase zeta and alteration of tyrosine metabolism following dichloroacetate exposure and withdrawal.
Topics: Acetone; Administration, Oral; Aging; Animals; Blotting, Western; Body Weight; Dichloroacetic Acid; | 2006 |
A longitudinal study of ammonia, acetone and propanol in the exhaled breath of 30 subjects using selected ion flow tube mass spectrometry, SIFT-MS.
Topics: 1-Propanol; Acetone; Adult; Aging; Ammonia; Blood Glucose; Body Mass Index; Breath Tests; Eating; Fe | 2006 |
Can ageing be prevented by dietary restriction?
Topics: Acetone; Acetyl Coenzyme A; Aging; Aldehyde Reductase; Animals; Caloric Restriction; Cytochrome P-45 | 2007 |
Stages of tumour promotion in skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Aging; Animals; Animals, Newborn; Carcinogens; Cell Divis | 1984 |
Aminoketone synthesis in rat liver: age dependence of basic activity and inducibility by allyl isopropyl acetamide.
Topics: 5-Aminolevulinate Synthetase; Acetone; Aging; Allylisopropylacetamide; Aminolevulinic Acid; Animals; | 1982 |
Influence of allyl isopropyl acetamide on d-aminolevulinic acid and aminoacetone synthesis during postnatal development in rats.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Acetone; Aging; Allylisopropylacetamide; Aminolevulinic Ac | 1982 |
Toxicities of 2,2',4,4'- and 3,3',4,4-tetrachlorobiphenyls to house flies at different ages and enzyme levels.
Topics: Abdomen; Acetone; Aging; Animals; Chromatography, Gas; Cytochrome P-450 Enzyme System; Female; House | 1995 |
Smell acuity for acetone and its relationship to taste ability to phenylthiocarbamide in a Nigerian population.
Topics: Acetone; Adolescent; Adult; Aging; Binomial Distribution; Child; Female; Gene Frequency; Humans; Lik | 1994 |
Age- and feeding-dependent production of carbonyl compounds in hypoxic heart. The role of carbonyls produced in connective tissue modification.
Topics: Acetone; Aging; Aldehydes; Amino Acids; Animals; Connective Tissue; Cyanogen Bromide; Diet; Hypoxia; | 1994 |
Repellence of the tick Rhipicephalus appendiculatus by the grass Melinis minutiflora.
Topics: Acetone; Aging; Analysis of Variance; Animals; Behavior, Animal; Chloroform; Female; Hexanes; Larva; | 1995 |
Exhaled isoprene and acetone in newborn infants and in children with diabetes mellitus.
Topics: Acetone; Adolescent; Aging; Butadienes; Child; Child, Preschool; Chromatography, Gas; Diabetes Melli | 1998 |
Do damaged proteins accumulate in Caenorhabditis elegans L-isoaspartate methyltransferase (pcm-1) deletion mutants?
Topics: Acetone; Aging; Animals; Autoantigens; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell | 1999 |
Perception of trigeminal chemosensory qualities in the elderly.
Topics: 1-Propanol; Acetic Acid; Acetone; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Cyclohexanols; | 2001 |
Inhibition of oxidation by peroxidase of human serum proteins.
Topics: Acetone; Aging; Antioxidants; Blood Proteins; Edetic Acid; gamma-Globulins; Humans; In Vitro Techniq | 1977 |
Chronic toxicity of acetone in the fresh water snail Lymnea stagnalis.
Topics: Acetone; Aging; Animals; Embryo, Nonmammalian; Fertility; Lymnaea | 1979 |
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part II: Quantitation of glutathione and glutathione disulfide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Topical; Aging; Animals; Carcinoma, Squam | 1991 |
Effects of ethanol on microsomal drug metabolism in aging female rats. I. Induction.
Topics: Acetone; Aging; Animals; Ethanol; Female; Glutathione; Microsomes, Liver; Oxidoreductases; Pharmaceu | 1989 |
Pathology of aging female SENCAR mice used as controls in skin two-stage carcinogenesis studies.
Topics: Acetone; Aging; Animals; Cardiovascular System; Female; Genitalia, Female; Hematopoietic System; Kid | 1986 |
Regulation of DNA synthesis in fat cells and stromal elements from rat adipose tissue.
Topics: Acetone; Adipose Tissue; Aging; Animals; Bicarbonates; Centrifugation; Chromatography; DNA; Epididym | 1969 |
Studies of the perinatal differences in the activity of hepatic -aminolevulinic acid synthetase.
Topics: 5-Aminolevulinate Synthetase; Acetone; Aging; Amines; Animals; Animals, Newborn; Bone Marrow; Chroma | 1972 |
Biosynthesis of galactolipids in plants.
Topics: Acetone; Aging; Carbon Isotopes; Chlorophyll; Chloroplasts; Chromatography, Thin Layer; Galactose; G | 1968 |
The cryptic nature of hepatic microsomal sulphite oxidase.
Topics: Acetone; Aging; Animals; Animals, Newborn; Bile Acids and Salts; Cell Nucleus; Embryo, Mammalian; Li | 1969 |
Ketone-body synthesis in relation to age of lambs.
Topics: Acetoacetates; Acetone; Aging; Animals; Animals, Newborn; Butyrates; Hydroxybutyrates; In Vitro Tech | 1964 |