Page last updated: 2024-10-16

acetone and Aging

acetone has been researched along with Aging in 26 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to determine how aging affects the induction by ethanol or acetone of the hepatic microsomal monooxygenase system of female Fischer 344 rats."3.67Effects of ethanol on microsomal drug metabolism in aging female rats. I. Induction. ( Rikans, LE, 1989)
"1) was increased several-fold on aging of microsomes, on delipidation by extraction with acetone or on solubilization with deoxycholate, suggesting its existence in a cryptic state."3.65The cryptic nature of hepatic microsomal sulphite oxidase. ( Joshi, VC; Kurup, CK; Ramasarma, T, 1969)
"Acetone treatment was used to perturb the skin barrier."1.31The skin barrier state of aged hairless mice in a dry environment. ( Ahn, SK; Chang, I; Choi, EH; Kim, MJ; Lee, SH; Nam, GW; Park, WS; Son, ED, 2002)
"Acetone was found to be the best of 5 solvents used to extract the tick-repellent substance."1.29Repellence of the tick Rhipicephalus appendiculatus by the grass Melinis minutiflora. ( Essuman, S; Kaaya, GP; Kimondo, MG; Munyinyi, D; Mwangi, EN; Nyandat, E, 1995)
"GSHt contents in squamous cell carcinomas (SCC) were twice the values measured in papillomas and 5- to 8-fold greater than the values measured in non-treated skins, and the non-tumorous tissue adjacent to SCC."1.28Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part II: Quantitation of glutathione and glutathione disulfide. ( Cappel, RE; Gilbert, HF; Kodari, E; Reiners, JJ, 1991)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199012 (46.15)18.7374
1990's7 (26.92)18.2507
2000's6 (23.08)29.6817
2010's0 (0.00)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Millecamps, M1
Shi, XQ1
Piltonen, M1
Echeverry, S1
Diatchenko, L1
Zhang, J1
Stone, LS1
Freemantle, E1
Vandal, M1
Tremblay Mercier, J1
Plourde, M1
Poirier, J1
Cunnane, SC1
Choi, EH1
Kim, MJ1
Ahn, SK1
Park, WS1
Son, ED1
Nam, GW1
Chang, I1
Lee, SH1
Guo, X1
Dixit, V1
Liu, H1
Shroads, AL1
Henderson, GN1
James, MO1
Stacpoole, PW1
Turner, C1
Spanel, P1
Smith, D1
Kalapos, MP1
Marks, F1
Fürstenberger, G1
Klinger, W2
Sommer, M1
Glöckner, R1
Saghir, SA1
Hansen, LG1
Odeigah, PG1
Deyl, Z1
Miksík, I1
Mwangi, EN1
Essuman, S1
Kaaya, GP1
Nyandat, E1
Munyinyi, D1
Kimondo, MG1
Nelson, N1
Lagesson, V1
Nosratabadi, AR1
Ludvigsson, J1
Tagesson, C1
Niewmierzycka, A1
Clarke, S1
Laska, M1
Gemant, A1
Bluzat, R1
Jonot, O1
Lespinasse, G1
Seugé, J1
Reiners, JJ1
Kodari, E1
Cappel, RE1
Gilbert, HF1
Rikans, LE1
Ward, JM1
Quander, R1
Devor, D1
Wenk, ML1
Spangler, EF1
Hollenberg, CH1
Vost, A1
Woods, JS1
Dixon, RL1
Ongun, A1
Mudd, JB1
Joshi, VC1
Kurup, CK1
Ramasarma, T1
Hird, FJ1
Weidemann, MJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pharmacotoxicology of Trichloroethylene Metabolites: Short-term Effect of DCA on in Vivo Tyrosine Catabolism and MAAI Expression[NCT00865514]2 participants (Actual)Interventional2011-08-31Terminated (stopped due to Difficulty in obtaining the solution from the compounding pharmacies caused a two year delay in start-up; the funding ended prior to study completion.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for acetone and Aging

ArticleYear
Metabolic response to a ketogenic breakfast in the healthy elderly.
    The journal of nutrition, health & aging, 2009, Volume: 13, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Apolipoprotein E4

2009

Other Studies

25 other studies available for acetone and Aging

ArticleYear
The geriatric pain experience in mice: intact cutaneous thresholds but altered responses to tonic and chronic pain.
    Neurobiology of aging, 2020, Volume: 89

    Topics: Acetone; Aging; Animals; Behavior; Biogenic Monoamines; Capsaicin; Chronic Pain; Disease Models, Ani

2020
The skin barrier state of aged hairless mice in a dry environment.
    The British journal of dermatology, 2002, Volume: 147, Issue:2

    Topics: Acetone; Aging; Animals; Environment; Epidermis; Lipid Metabolism; Mice; Mice, Nude; Microscopy, Ele

2002
Inhibition and recovery of rat hepatic glutathione S-transferase zeta and alteration of tyrosine metabolism following dichloroacetate exposure and withdrawal.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:1

    Topics: Acetone; Administration, Oral; Aging; Animals; Blotting, Western; Body Weight; Dichloroacetic Acid;

2006
A longitudinal study of ammonia, acetone and propanol in the exhaled breath of 30 subjects using selected ion flow tube mass spectrometry, SIFT-MS.
    Physiological measurement, 2006, Volume: 27, Issue:4

    Topics: 1-Propanol; Acetone; Adult; Aging; Ammonia; Blood Glucose; Body Mass Index; Breath Tests; Eating; Fe

2006
Can ageing be prevented by dietary restriction?
    Mechanisms of ageing and development, 2007, Volume: 128, Issue:2

    Topics: Acetone; Acetyl Coenzyme A; Aging; Aldehyde Reductase; Animals; Caloric Restriction; Cytochrome P-45

2007
Stages of tumour promotion in skin.
    IARC scientific publications, 1984, Issue:56

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Aging; Animals; Animals, Newborn; Carcinogens; Cell Divis

1984
Aminoketone synthesis in rat liver: age dependence of basic activity and inducibility by allyl isopropyl acetamide.
    Acta biologica et medica Germanica, 1982, Volume: 41, Issue:9

    Topics: 5-Aminolevulinate Synthetase; Acetone; Aging; Allylisopropylacetamide; Aminolevulinic Acid; Animals;

1982
Influence of allyl isopropyl acetamide on d-aminolevulinic acid and aminoacetone synthesis during postnatal development in rats.
    Acta biologica et medica Germanica, 1982, Volume: 41, Issue:9

    Topics: 5-Aminolevulinate Synthetase; Acetamides; Acetone; Aging; Allylisopropylacetamide; Aminolevulinic Ac

1982
Toxicities of 2,2',4,4'- and 3,3',4,4-tetrachlorobiphenyls to house flies at different ages and enzyme levels.
    Archives of environmental contamination and toxicology, 1995, Volume: 28, Issue:4

    Topics: Abdomen; Acetone; Aging; Animals; Chromatography, Gas; Cytochrome P-450 Enzyme System; Female; House

1995
Smell acuity for acetone and its relationship to taste ability to phenylthiocarbamide in a Nigerian population.
    East African medical journal, 1994, Volume: 71, Issue:7

    Topics: Acetone; Adolescent; Adult; Aging; Binomial Distribution; Child; Female; Gene Frequency; Humans; Lik

1994
Age- and feeding-dependent production of carbonyl compounds in hypoxic heart. The role of carbonyls produced in connective tissue modification.
    Mechanisms of ageing and development, 1994, Volume: 73, Issue:1

    Topics: Acetone; Aging; Aldehydes; Amino Acids; Animals; Connective Tissue; Cyanogen Bromide; Diet; Hypoxia;

1994
Repellence of the tick Rhipicephalus appendiculatus by the grass Melinis minutiflora.
    Tropical animal health and production, 1995, Volume: 27, Issue:4

    Topics: Acetone; Aging; Analysis of Variance; Animals; Behavior, Animal; Chloroform; Female; Hexanes; Larva;

1995
Exhaled isoprene and acetone in newborn infants and in children with diabetes mellitus.
    Pediatric research, 1998, Volume: 44, Issue:3

    Topics: Acetone; Adolescent; Aging; Butadienes; Child; Child, Preschool; Chromatography, Gas; Diabetes Melli

1998
Do damaged proteins accumulate in Caenorhabditis elegans L-isoaspartate methyltransferase (pcm-1) deletion mutants?
    Archives of biochemistry and biophysics, 1999, Apr-15, Volume: 364, Issue:2

    Topics: Acetone; Aging; Animals; Autoantigens; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell

1999
Perception of trigeminal chemosensory qualities in the elderly.
    Chemical senses, 2001, Volume: 26, Issue:6

    Topics: 1-Propanol; Acetic Acid; Acetone; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Cyclohexanols;

2001
Inhibition of oxidation by peroxidase of human serum proteins.
    Molecular biology reports, 1977, Volume: 3, Issue:4

    Topics: Acetone; Aging; Antioxidants; Blood Proteins; Edetic Acid; gamma-Globulins; Humans; In Vitro Techniq

1977
Chronic toxicity of acetone in the fresh water snail Lymnea stagnalis.
    Toxicology, 1979, Volume: 14, Issue:2

    Topics: Acetone; Aging; Animals; Embryo, Nonmammalian; Fertility; Lymnaea

1979
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part II: Quantitation of glutathione and glutathione disulfide.
    Carcinogenesis, 1991, Volume: 12, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Topical; Aging; Animals; Carcinoma, Squam

1991
Effects of ethanol on microsomal drug metabolism in aging female rats. I. Induction.
    Mechanisms of ageing and development, 1989, Volume: 48, Issue:3

    Topics: Acetone; Aging; Animals; Ethanol; Female; Glutathione; Microsomes, Liver; Oxidoreductases; Pharmaceu

1989
Pathology of aging female SENCAR mice used as controls in skin two-stage carcinogenesis studies.
    Environmental health perspectives, 1986, Volume: 68

    Topics: Acetone; Aging; Animals; Cardiovascular System; Female; Genitalia, Female; Hematopoietic System; Kid

1986
Regulation of DNA synthesis in fat cells and stromal elements from rat adipose tissue.
    The Journal of clinical investigation, 1969, Volume: 47, Issue:11

    Topics: Acetone; Adipose Tissue; Aging; Animals; Bicarbonates; Centrifugation; Chromatography; DNA; Epididym

1969
Studies of the perinatal differences in the activity of hepatic -aminolevulinic acid synthetase.
    Biochemical pharmacology, 1972, Jun-15, Volume: 21, Issue:12

    Topics: 5-Aminolevulinate Synthetase; Acetone; Aging; Amines; Animals; Animals, Newborn; Bone Marrow; Chroma

1972
Biosynthesis of galactolipids in plants.
    The Journal of biological chemistry, 1968, Apr-10, Volume: 243, Issue:7

    Topics: Acetone; Aging; Carbon Isotopes; Chlorophyll; Chloroplasts; Chromatography, Thin Layer; Galactose; G

1968
The cryptic nature of hepatic microsomal sulphite oxidase.
    The Biochemical journal, 1969, Volume: 111, Issue:3

    Topics: Acetone; Aging; Animals; Animals, Newborn; Bile Acids and Salts; Cell Nucleus; Embryo, Mammalian; Li

1969
Ketone-body synthesis in relation to age of lambs.
    The Biochemical journal, 1964, Volume: 93, Issue:2

    Topics: Acetoacetates; Acetone; Aging; Animals; Animals, Newborn; Butyrates; Hydroxybutyrates; In Vitro Tech

1964