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acetohydroxamic acid and Kidney Stones

acetohydroxamic acid has been researched along with Kidney Stones in 16 studies

acetohydroxamic acid: urease inhibitor
oxime : Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes.
N-hydroxyacetimidic acid : A carbohydroximic acid consisting of acetimidic acid having a hydroxy group attached to the imide nitrogen.
acetohydroxamic acid : A member of the class of acetohydroxamic acids that is acetamide in which one of the amino hydrogens has been replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Thrombosis has been observed with unusual frequency in patients receiving acetohydroxamic acid (AHA) for treatment of struvite nephrolithiasis."3.67Hypercoagulability produced by treatment with acetohydroxamic acid. ( Jones, RL; Rodman, JS; Williams, JJ, 1987)
" Nine patients receiving the drug and one patient receiving placebo required a decrease in dosage or cessation of treatment because of adverse effects (P less than 0."2.65A randomized double-blind study of acetohydroxamic acid in struvite nephrolithiasis. ( Peterson, CM; Rodman, JS; Williams, JJ, 1984)
"Struvite stones have been associated with significant morbidity and mortality, yet there has not been a report on the medical management of struvite stones in almost 20 years."1.43Contemporary Management of Struvite Stones Using Combined Endourologic and Medical Treatment: Predictors of Unfavorable Clinical Outcome. ( Ferrandino, MN; Hanna, J; Iqbal, MW; Kuntz, N; Lipkin, ME; Neisius, A; Preminger, GM; Youssef, RF, 2016)
" Parameter estimates from 14CO2 concentrations in breath as a function of time data closely correspond to the pharmacokinetic parameters of AHA in patients indicating that CO2 may be a primary metabolite derived directly from AHA rather than a secondary metabolite formed by the metabolism of an intermediate product."1.27Pharmacokinetics of acetohydroxamic acid in patients with staghorn renal calculi. ( Feldman, S; Griffith, DP; Putcha, L, 1985)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199014 (87.50)18.7374
1990's1 (6.25)18.2507
2000's0 (0.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iqbal, MW1
Youssef, RF1
Neisius, A1
Kuntz, N1
Hanna, J1
Ferrandino, MN1
Preminger, GM1
Lipkin, ME1
Rodman, JS3
Williams, JJ3
Peterson, CM2
Smith, LH1
Marwick, C1
Rosenstein, I1
Hamilton-Miller, JM1
Brumfitt, W1
Martelli, A3
Buli, P3
Brunocilla, E1
Cortecchia, V2
Nadler, RB1
Hoffman, TA1
McClennan, BL1
Clayman, RV1
Lorenz, J2
Lorenz, K2
Dabrowska, B2
Kowal, R2
Jones, RL1
Morote Robles, J1
Ruiz Marcellán, FJ1
Bernstham Ballester, J1
Pinto Mateos, B1
Soler Roselló, A1
Putcha, L1
Griffith, DP1
Feldman, S1

Trials

1 trial available for acetohydroxamic acid and Kidney Stones

ArticleYear
A randomized double-blind study of acetohydroxamic acid in struvite nephrolithiasis.
    The New England journal of medicine, 1984, Sep-20, Volume: 311, Issue:12

    Topics: Adult; Double-Blind Method; Drug Evaluation; Female; Humans; Hydroxamic Acids; Kidney Calculi; Magne

1984

Other Studies

15 other studies available for acetohydroxamic acid and Kidney Stones

ArticleYear
Contemporary Management of Struvite Stones Using Combined Endourologic and Medical Treatment: Predictors of Unfavorable Clinical Outcome.
    Journal of endourology, 2016, Volume: 30, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Calcium Citrate; Chlorthalidone; Comorbidity;

2016
Partial dissolution of struvite calculus with oral acetohydroxamic acid.
    Urology, 1983, Volume: 22, Issue:4

    Topics: Administration, Oral; Adult; Colic; Female; Humans; Hydroxamic Acids; Kidney; Kidney Calculi; Kidney

1983
New treatment for struvite urinary stones.
    The New England journal of medicine, 1984, Sep-20, Volume: 311, Issue:12

    Topics: Humans; Hydroxamic Acids; Kidney Calculi; Magnesium; Magnesium Compounds; Phosphates; Struvite; Urin

1984
Oral acetohydroxamic acid (LithoStat) for staghorn calculi.
    The Medical letter on drugs and therapeutics, 1983, Dec-09, Volume: 25, Issue:650

    Topics: Humans; Hydroxamic Acids; Kidney Calculi; Urease

1983
New drugs selectively inhibit kidney stone formation.
    JAMA, 1983, Jul-15, Volume: 250, Issue:3

    Topics: Calcium; Cellulose; Citrates; Citric Acid; Humans; Hydroxamic Acids; Kidney Calculi; United States;

1983
The effect of acetohydroxamic acid on the induction of bacterial ureases.
    Investigative urology, 1980, Volume: 18, Issue:2

    Topics: Enzyme Induction; Hydroxamic Acids; Kidney Calculi; Proteus; Proteus Infections; Proteus mirabilis;

1980
Propionohydroxamic acid in infected renal stones. A preliminary clinical report.
    The Journal of urology, 1982, Volume: 128, Issue:5

    Topics: Adult; Female; Humans; Hydroxamic Acids; Kidney Calculi; Klebsiella Infections; Male; Middle Aged; P

1982
Acetohydroxamic acid therapy in infected renal stones.
    Urology, 1981, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Drug Synergism; Female; Humans; Hydrogen-Ion Concentration

1981
Urease inhibitor therapy in infected renal stones.
    European urology, 1981, Volume: 7, Issue:5

    Topics: Adolescent; Anti-Infective Agents, Urinary; Drug Therapy, Combination; Female; History, 16th Century

1981
Corynebacterium urealyticum (CDC Group D2) associated with staghorn calculus: treatment by percutaneous debulking and chemolysis.
    Journal of endourology, 1996, Volume: 10, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Corynebacterium; Corynebacterium Infections; Follow-Up Studies; Humans

1996
[Acetylhydroxamic acid in the treatment of nephrolithiasis, caused by infection with urease forming microorganisms].
    Zeitschrift fur Urologie und Nephrologie, 1989, Volume: 82, Issue:12

    Topics: Ammonia; Humans; Hydrogen-Ion Concentration; Hydroxamic Acids; Kidney Calculi; Microbial Sensitivity

1989
[Acetohydroxamic acid in the treatment of kidney calculi caused by an infection with urease-producing microorganisms].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1987, May-04, Volume: 42, Issue:18

    Topics: Bacteriuria; Humans; Hydroxamic Acids; Kidney Calculi; Proteus Infections; Proteus vulgaris; Urease

1987
Hypercoagulability produced by treatment with acetohydroxamic acid.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:3

    Topics: Blood Coagulation; Fibrinopeptide A; Humans; Hydroxamic Acids; Kidney Calculi; Middle Aged; Platelet

1987
[Clinical study of the treatment of infectious renal lithiasis with acetohydroxamic acid].
    Medicina clinica, 1986, Jun-21, Volume: 87, Issue:4

    Topics: Adult; Aged; Bacterial Infections; Female; Humans; Hydroxamic Acids; Kidney Calculi; Male; Middle Ag

1986
Pharmacokinetics of acetohydroxamic acid in patients with staghorn renal calculi.
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:4

    Topics: Acetamides; Adult; Aged; Carbon Dioxide; Carbon Radioisotopes; Female; Humans; Hydroxamic Acids; Kid

1985