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acetoacetic acid and Pregnancy

acetoacetic acid has been researched along with Pregnancy in 42 studies

acetoacetic acid : A 3-oxo monocarboxylic acid that is butyric acid bearing a 3-oxo substituent.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Changes in the number, maturity and function of neutrophils, concomitant changes in plasma concentrations of hormones and metabolites, and the increased susceptibility of cows to infectious diseases around parturition, led us to investigate the effect of beta-hydroxybutyric acid (BHBA), acetoacetic acid (AcAc), hydrocortisone-21-acetate (HCAc) and bovine pregnancy-associated glycoprotein (bPAG) on the proliferation of bovine bone marrow progenitor cells in methylcellulose in vitro cultures."3.70In vitro effect of ketone bodies, glucocorticosteroids and bovine pregnancy-associated glycoprotein on cultures of bone marrow progenitor cells of cows and calves. ( Beckers, JF; Burvenich, C; Hoeben, D; Lenjou, M; Massart-Leën, AM; Nijs, G; Van Bockstaele, D, 1999)
"Monensin-treated cows had significantly decreased NEFA and BHBA and significantly increased concentrations of serum cholesterol and urea in the week immediately precalving."2.71Effect of a monensin controlled release capsule on metabolic parameters in transition dairy cows. ( Bagg, R; Dick, P; Duffield, TF; LeBlanc, S; Leslie, K; Ten Hag, J, 2003)
" A lignolytic enzyme preparation produced by the thermophilic fungus Thermomyces lanuginosus was applied in the present experiment and fed to dairy cows at 34 g/day dosage in the period between calving and the 110th day of lactation."2.70Effects of a non-starch polysaccharidase enzyme preparation from Thermomyces lanuginosus on energy and protein metabolism and milk yield of dairy cattle. ( Bartyik, J; Bata, A; Brydl, E; Fülöp, A; Jurkovich, V; Könyves, L; Kutasi, J; Nagy, G; Rafai, P; Tegzes, L, 2002)
"Pregnancy is characterized by a rapid accumulation of lipid stores during the first half of gestation and a utilization of these stores during the latter half of gestation."2.37Ketone body metabolism in the mother and fetus. ( Shambaugh, GE, 1985)
"Our results suggest that genetic susceptibility plays an important role in inducing underdevelopment and NTD in cultured CDs embryos in sub-teratogenic medium and in protecting the CDr embryos under the same conditions."1.32Reduced SOD activity and increased neural tube defects in embryos of the sensitive but not of the resistant Cohen diabetic rats cultured under diabetic conditions. ( Ornoy, A; Weksler-Zangen, S; Yaffe, P, 2003)
"The sample proportion of subclinical ketosis was 7."1.32Evaluation and use of three cowside tests for detection of subclinical ketosis in early postpartum cows. ( Carrier, J; Fetrow, J; Godden, S; Rapnicki, P; Stewart, S, 2004)
"Propionic acid was used as a possible preventive agent against ketogenesis."1.27Effect of propionic acid on ketogenesis in lactating sheep fed restricted rations or deprived of food. ( Emmanuel, B; Kennelly, JJ, 1984)
"Data show that ethanol treatment during pregnancy alters glucose-insulin relationships despite being associated with unchanged maternal glycemia."1.27Effects of chronic ethanol treatment on glucose tolerance, insulin response and circulating metabolites in the pregnant rat. ( Mampel, T; Villarroya, F, 1985)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199025 (59.52)18.7374
1990's5 (11.90)18.2507
2000's7 (16.67)29.6817
2010's3 (7.14)24.3611
2020's2 (4.76)2.80

Authors

AuthorsStudies
Whatley, EG2
Truong, TT2
Harvey, AJ2
Gardner, DK2
Akram, M1
Orczyk-Pawilowicz, M1
Jawien, E1
Deja, S1
Hirnle, L1
Zabek, A1
Mlynarz, P1
Kurepa, D1
Pramanik, AK1
Kakkilaya, V1
Caldito, G1
Groome, LJ1
Bocchini, JA1
Jain, SK1
Jurkovich, V1
Brydl, E1
Rafai, P1
Könyves, L1
Tegzes, L1
Kutasi, J1
Bata, A1
Nagy, G1
Bartyik, J1
Fülöp, A1
Duffield, TF1
LeBlanc, S1
Bagg, R1
Leslie, K1
Ten Hag, J1
Dick, P1
Massieu, L1
Haces, ML1
Montiel, T1
Hernández-Fonseca, K1
Weksler-Zangen, S1
Yaffe, P2
Ornoy, A4
BERGMAN, EN2
KON, K2
Jánosi, S1
Kulcsár, M1
Kóródi, P1
Kátai, L1
Reiczigel, J1
Dieleman, SJ1
Nikolic, JA1
Sályi, G1
Ribiczey-Szabó, P1
Huszenicza, G1
Carrier, J1
Stewart, S1
Godden, S1
Fetrow, J1
Rapnicki, P1
Agius, L1
Williamson, DH1
Kauppinen, K4
Roth, KS1
Serabian, M1
Medow, MS1
Palou, A2
Remesar, X2
Arola, L1
Alemany, M1
Gröhn, Y2
Lindberg, LA1
Bruss, ML1
Farver, TB1
Emmanuel, B1
Kennelly, JJ1
Shambaugh, GE3
Angulo, MC1
Koehler, RR1
Laarveld, B1
DeLorme, B1
Kerr, DE1
Koehler, RA1
Sparks, JW3
Pegorier, JP1
Girard, J2
Battaglia, FC3
Moley, KH1
Vaughn, WK1
Diamond, MP2
Shubert, PJ1
Gordon, MC1
Landon, MB1
Gabbe, SG1
Kniss, DA1
Fukao, T1
Song, XQ1
Watanabe, H1
Hirayama, K1
Sakazaki, H1
Shintaku, H1
Imanaka, M1
Orii, T1
Kondo, N1
Hoeben, D1
Burvenich, C1
Massart-Leën, AM1
Lenjou, M1
Nijs, G1
Van Bockstaele, D1
Beckers, JF1
Zaken, V1
Kohen, R1
Connolly, CC1
Holste, LC1
Aglione, LN1
Neal, DW1
Lacy, DB1
Smith, MS1
Cherrington, AD1
Chiasson, JL1
Roca, P1
Gianotti, M1
Willems, PJ1
Dijkstra, I1
Schierbeek, HH1
Berger, R1
Smit, GP1
Block, SM1
Johnson, RL1
Vilaró, S1
Viñas, O1
Herrera, E1
Zusman, I2
Villarroya, F1
Mampel, T1
Gilbert, M1

Reviews

2 reviews available for acetoacetic acid and Pregnancy

ArticleYear
A focused review of the role of ketone bodies in health and disease.
    Journal of medicinal food, 2013, Volume: 16, Issue:11

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Alzheimer Disease; Blood Glucose; Diabetic Ketoacidos

2013
Ketone body metabolism in the mother and fetus.
    Federation proceedings, 1985, Volume: 44, Issue:7

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Brain; Embryonic and Fetal Development; Female; Gluco

1985

Trials

2 trials available for acetoacetic acid and Pregnancy

ArticleYear
Effects of a non-starch polysaccharidase enzyme preparation from Thermomyces lanuginosus on energy and protein metabolism and milk yield of dairy cattle.
    Acta veterinaria Hungarica, 2002, Volume: 50, Issue:4

    Topics: Acetoacetates; Animal Feed; Animals; Aspartate Aminotransferases; Cattle; Dairying; Energy Metabolis

2002
Effect of a monensin controlled release capsule on metabolic parameters in transition dairy cows.
    Journal of dairy science, 2003, Volume: 86, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Animals; Blood Glucose; Calcium; Cattle; Cholesterol;

2003

Other Studies

38 other studies available for acetoacetic acid and Pregnancy

ArticleYear
Acetoacetate and β-hydroxybutyrate reduce mouse embryo viability via differential metabolic and epigenetic mechanisms.
    Reproductive biomedicine online, 2023, Volume: 46, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Female; Histones; Humans; Ketones; Mice; Placenta; Pr

2023
Preimplantation embryo exposure to ketone bodies exerts sex-specific effects on mouse fetal and placental transcriptomes.
    Reproductive biomedicine online, 2023, Volume: 47, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Blastocyst; Female; Ketone Bodies; Ketones; Male; Mice; Placenta; Pr

2023
Metabolomics of Human Amniotic Fluid and Maternal Plasma during Normal Pregnancy.
    PloS one, 2016, Volume: 11, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Amino Acids; Amniotic Fluid; Female; Fetal Development;

2016
Elevated acetoacetate and monocyte chemotactic protein-1 levels in cord blood of infants of diabetic mothers.
    Neonatology, 2012, Volume: 102, Issue:3

    Topics: Acetoacetates; Adult; Case-Control Studies; Chemokine CCL2; Diabetes Mellitus, Type 1; Diabetes, Ges

2012
Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition.
    Neuroscience, 2003, Volume: 120, Issue:2

    Topics: Acetoacetates; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Dicarboxylic Acids;

2003
Reduced SOD activity and increased neural tube defects in embryos of the sensitive but not of the resistant Cohen diabetic rats cultured under diabetic conditions.
    Birth defects research. Part A, Clinical and molecular teratology, 2003, Volume: 67, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Catalase; Diabetes Mellitus, Type 2; Disease Models,

2003
ACETOACETATE TURNOVER AND OXIDATION RATES IN OVINE PREGNANCY KETOSIS.
    The American journal of physiology, 1964, Volume: 206

    Topics: Acetoacetates; Acidosis; Animals; Blood Chemical Analysis; Carbon Isotopes; Fasting; Female; Glucose

1964
FACTORS AFFECTING ACETOACETATE PRODUCTION RATES BY NORMAL AND KETOTIC PREGNANT SHEEP.
    The American journal of physiology, 1964, Volume: 206

    Topics: Acetoacetates; Acidosis; Animals; Blood Chemical Analysis; Butyrates; Female; Glucose; Growth Hormon

1964
Energy imbalance related predisposition to mastitis in group-fed high-producing postpartum dairy cows.
    Acta veterinaria Hungarica, 2003, Volume: 51, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Aspartate Aminotransferases; Blood Glucose; Cattle; C

2003
Evaluation and use of three cowside tests for detection of subclinical ketosis in early postpartum cows.
    Journal of dairy science, 2004, Volume: 87, Issue:11

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Cattle; Cattle Diseases; False Negative Reactions; Fa

2004
The utilization of ketone bodies by the interscapular brown adipose tissue of the rat.
    Biochimica et biophysica acta, 1981, Oct-23, Volume: 666, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetyl-CoA C-Acetyltransferase; Adipose Tissue, Brown; Animals

1981
ALAT, AP, ASAT, GGT, OCT activities and urea and total bilirubin concentrations in plasma of normal and ketotic dairy cows.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1984, Volume: 31, Issue:8

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Alanine Transaminase; Alkaline Phosphatase; Animals;

1984
A comparison of the uptake of 3-hydroxy-3-methyl-glutaric acid in newborn and adult rat kidney.
    Metabolism: clinical and experimental, 1982, Volume: 31, Issue:4

    Topics: Acetoacetates; Aminoisobutyric Acids; Animals; Animals, Newborn; Female; Glutarates; Keto Acids; Kid

1982
Changes induced in rat plasma composition by lactation.
    Archives internationales de physiologie et de biochimie, 1982, Volume: 90, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids; Animals; Blood Glucose; Female; Glycerol; Hydroxy

1982
Annual milk yield and reproductive performance of ketotic and non-ketotic dairy cows.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1984, Volume: 31, Issue:9

    Topics: Acetoacetates; Acidosis; Animals; Cattle; Cattle Diseases; Female; Ketosis; Lactation; Milk; Pregnan

1984
Fatty infiltration of liver in spontaneously ketotic dairy cows.
    Journal of dairy science, 1983, Volume: 66, Issue:11

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Biopsy, Needle; Blood Glucose; Cattle; Catt

1983
Prevalence of bovine ketosis in relation to number and stage of lactation.
    Acta veterinaria Scandinavica, 1983, Volume: 24, Issue:4

    Topics: Acetoacetates; Acidosis; Animals; Cattle; Cattle Diseases; Female; Finland; Ketosis; Lactation; Pari

1983
Correlation of whole blood concentrations of acetoacetate, beta-hydroxybutyrate, glucose and milk yield in dairy cows as studied under field conditions.
    Acta veterinaria Scandinavica, 1983, Volume: 24, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Cattle; Dairying; Female; Hydroxybutyr

1983
Effect of propionic acid on ketogenesis in lactating sheep fed restricted rations or deprived of food.
    Journal of dairy science, 1984, Volume: 67, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Blood Glucose; Diet; Fatty Acids, Nonesteri

1984
Fetal fuels. VII. Ketone bodies inhibit synthesis of purines in fetal rat brain.
    The American journal of physiology, 1984, Volume: 247, Issue:1 Pt 1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenine; Animals; Brain; Carbon Radioisotopes; Cycloheximide;

1984
Lipotropic effect of estradiol-17 beta in fed and fasted lactating cows.
    Journal of dairy science, 1982, Volume: 65, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Cattle; Cholesterol; Estradiol; Fastin

1982
Fetal fuels. IV. Regulation of branched-chain amino and keto acid metabolism in fetal brain.
    The American journal of physiology, 1981, Volume: 241, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Brain; Female; Fetus; Hydroxybutyrates; Keto Acids; K

1981
Substrate concentration changes during pregnancy in the guinea pig studied under unstressed steady state conditions.
    Pediatric research, 1981, Volume: 15, Issue:10

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Body Weight; Fatty Acids, Nonesterifie

1981
Manifestations of diabetes mellitus on mouse preimplantation development: effect of elevated concentration of metabolic intermediates.
    Human reproduction (Oxford, England), 1994, Volume: 9, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids; Animals; Butyrates; Cleavage Stage, Ovum; Culture

1994
Ketoacids attenuate glucose uptake in human trophoblasts isolated from first-trimester chorionic villi.
    American journal of obstetrics and gynecology, 1996, Volume: 175, Issue:1

    Topics: Acetoacetates; Cells, Cultured; Chorionic Villi; Female; Glucose; Glucose Transporter Type 1; Humans

1996
Prenatal diagnosis of succinyl-coenzyme A:3-ketoacid coenzyme A transferase deficiency.
    Prenatal diagnosis, 1996, Volume: 16, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetyl-CoA C-Acetyltransferase; Amniocentesis; Amniotic Fluid;

1996
In vitro effect of ketone bodies, glucocorticosteroids and bovine pregnancy-associated glycoprotein on cultures of bone marrow progenitor cells of cows and calves.
    Veterinary immunology and immunopathology, 1999, Volume: 68, Issue:2-4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Aspartic Acid Endopeptidases; Bone Marrow; Cattle; Ce

1999
Role of reactive oxygen species (ROS) in the diabetes-induced anomalies in rat embryos in vitro: reduction in antioxidant enzymes and low-molecular-weight antioxidants (LMWA) may be the causative factor for increased anomalies.
    Teratology, 1999, Volume: 60, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Antioxidants; Ascorbic Acid; Catalase; Congenital Abn

1999
Alterations in basal glucose metabolism during late pregnancy in the conscious dog.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Amino Acids; Animals; Arteries; Blood Glucose; Dogs;

2000
Metabolic response to short term starvation in non-pregnant and late pregnant cafeteria-obese rats.
    Archives internationales de physiologie et de biochimie, 1989, Volume: 97, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Female; Fetal Blood; Glycerol; Hydroxy

1989
Activation of fatty acid oxidation in the Silver-Russell syndrome and the Brachmann-de Lange syndrome.
    American journal of medical genetics, 1988, Volume: 30, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Dicarboxylic Acids; Facial Bones; Fatty Acids; Female; Fetal G

1988
Uterine metabolism of the pregnant guinea pig as a function of gestational age.
    Pediatric research, 1988, Volume: 23, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetates; Acetoacetates; Animals; Blood Glucose; Female; Gestational Age; Gui

1988
Chronic and acute ethanol impair the in vivo glucose uptake by lactating rat mammary gland.
    Bioscience reports, 1987, Volume: 7, Issue:10

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Ethanol; Female; Hydroxybutyrates; Lac

1987
Effects of hyperglycemia and ketone bodies on the in vitro development of early somite rate embryos.
    Pediatric pathology, 1987, Volume: 7, Issue:5-6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Blood Glucose; Congenital Abnormalities; Cu

1987
Effects of metabolic factors in the diabetic state on the in vitro development of preimplantation mouse embryos.
    Teratology, 1987, Volume: 35, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blastocyst; Culture Techniques; Diabetes Mellitus, Ex

1987
Effects of chronic ethanol treatment on glucose tolerance, insulin response and circulating metabolites in the pregnant rat.
    General pharmacology, 1985, Volume: 16, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Body Weight; Energy Intake; Ethanol; F

1985
Propionate loading test for liver function in spontaneously ketotic dairy cows.
    Research in veterinary science, 1985, Volume: 39, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Blood Glucose; Cattle; Cattle Diseases; Fem

1985
Effects of fasting on glucose turnover rate and metabolite levels in conscious pregnant guinea pigs.
    Biology of the neonate, 1985, Volume: 48, Issue:2

    Topics: Acetates; Acetoacetates; Amino Acids; Animals; Fasting; Fatty Acids, Nonesterified; Female; Fetus; G

1985