Page last updated: 2024-10-15

acetoacetic acid and Parkinson Disease

acetoacetic acid has been researched along with Parkinson Disease in 1 studies

acetoacetic acid : A 3-oxo monocarboxylic acid that is butyric acid bearing a 3-oxo substituent.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"Unified Parkinson's Disease Rating Scale scores improved in all five during hyperketonemia, but a placebo effect was not ruled out."2.71Treatment of Parkinson disease with diet-induced hyperketonemia: a feasibility study. ( Boyar, K; Di Rocco, A; Heymsfield, SB; Hyams, K; Nonas, C; Vanitallie, TB, 2005)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vanitallie, TB1
Nonas, C1
Di Rocco, A1
Boyar, K1
Hyams, K1
Heymsfield, SB1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ketogenic Diet Interventions in Parkinson's Disease: Safeguarding the Gut Microbiome[NCT05469997]50 participants (Anticipated)Interventional2023-01-31Not yet recruiting
Effect of a Lipidic and Proteic Controlled Diet on Resting Energy Expenditure, Body Composition and Symptoms in Patients With Parkinson's Disease[NCT02687698]36 participants (Anticipated)Interventional2016-02-29Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for acetoacetic acid and Parkinson Disease

ArticleYear
Treatment of Parkinson disease with diet-induced hyperketonemia: a feasibility study.
    Neurology, 2005, Feb-22, Volume: 64, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aged; Antiparkinson Agents; Cholesterol; Combined Modality The

2005
Treatment of Parkinson disease with diet-induced hyperketonemia: a feasibility study.
    Neurology, 2005, Feb-22, Volume: 64, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aged; Antiparkinson Agents; Cholesterol; Combined Modality The

2005
Treatment of Parkinson disease with diet-induced hyperketonemia: a feasibility study.
    Neurology, 2005, Feb-22, Volume: 64, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aged; Antiparkinson Agents; Cholesterol; Combined Modality The

2005
Treatment of Parkinson disease with diet-induced hyperketonemia: a feasibility study.
    Neurology, 2005, Feb-22, Volume: 64, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aged; Antiparkinson Agents; Cholesterol; Combined Modality The

2005