Page last updated: 2024-10-15

acetoacetic acid and Liver Dysfunction

acetoacetic acid has been researched along with Liver Dysfunction in 5 studies

acetoacetic acid : A 3-oxo monocarboxylic acid that is butyric acid bearing a 3-oxo substituent.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effects of acute pancreatitis on the energy metabolism of the liver and on the fragility of hepatic cells and subcellular organelles, we studies (1) the arterial blood ketone body ratio (BKBR) (aceto acetate/beta-hydroxy butyrate), which is in equilibrium with the free NAD+/NADH ratio in liver mitochondria; (2) the hepatic energy charge (EC) = (ATP + 1/2 ADP)/(ATP + ADP + AMP); (3) the cathepsin B leakage from hepatic lysosomes and the malate dehydrogenase leakage from hepatic mitochondria in vitro; and (4) the protective effects of prostaglandin E2 (PGE2) and a new synthetic protease inhibitor ONO 3307 on hepatic injury in acute pancreatitis induced in rats by a supramaximal dose of caerulein."7.68Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307. ( Hirano, T; Manabe, T; Tobe, T, 1992)
"To evaluate the effects of acute pancreatitis on the energy metabolism of the liver and on the fragility of hepatic cells and subcellular organelles, we studies (1) the arterial blood ketone body ratio (BKBR) (aceto acetate/beta-hydroxy butyrate), which is in equilibrium with the free NAD+/NADH ratio in liver mitochondria; (2) the hepatic energy charge (EC) = (ATP + 1/2 ADP)/(ATP + ADP + AMP); (3) the cathepsin B leakage from hepatic lysosomes and the malate dehydrogenase leakage from hepatic mitochondria in vitro; and (4) the protective effects of prostaglandin E2 (PGE2) and a new synthetic protease inhibitor ONO 3307 on hepatic injury in acute pancreatitis induced in rats by a supramaximal dose of caerulein."5.28Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307. ( Hirano, T; Manabe, T; Tobe, T, 1992)
"To evaluate the effects of acute pancreatitis on the energy metabolism of the liver and on the fragility of hepatic cells and subcellular organelles, we studies (1) the arterial blood ketone body ratio (BKBR) (aceto acetate/beta-hydroxy butyrate), which is in equilibrium with the free NAD+/NADH ratio in liver mitochondria; (2) the hepatic energy charge (EC) = (ATP + 1/2 ADP)/(ATP + ADP + AMP); (3) the cathepsin B leakage from hepatic lysosomes and the malate dehydrogenase leakage from hepatic mitochondria in vitro; and (4) the protective effects of prostaglandin E2 (PGE2) and a new synthetic protease inhibitor ONO 3307 on hepatic injury in acute pancreatitis induced in rats by a supramaximal dose of caerulein."3.68Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307. ( Hirano, T; Manabe, T; Tobe, T, 1992)
"To evaluate the effects of acute pancreatitis on the energy metabolism of the liver and on the fragility of hepatic cells and subcellular organelles, we studies (1) the arterial blood ketone body ratio (BKBR) (aceto acetate/beta-hydroxy butyrate), which is in equilibrium with the free NAD+/NADH ratio in liver mitochondria; (2) the hepatic energy charge (EC) = (ATP + 1/2 ADP)/(ATP + ADP + AMP); (3) the cathepsin B leakage from hepatic lysosomes and the malate dehydrogenase leakage from hepatic mitochondria in vitro; and (4) the protective effects of prostaglandin E2 (PGE2) and a new synthetic protease inhibitor ONO 3307 on hepatic injury in acute pancreatitis induced in rats by a supramaximal dose of caerulein."1.28Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307. ( Hirano, T; Manabe, T; Tobe, T, 1992)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
FELIX, K1
LEONHARDI, G1
von GLASENAPP, I1
Higashi, S1
Tabata, N1
Kondo, KH1
Kai, M1
Miyamoto, K1
Maeda, Y1
Setoguchi, T1
Hirano, T1
Manabe, T1
Tobe, T1
Schlichtig, R1
Klions, HA1
Kramer, DJ1
Nemoto, EM1
Iwata, S1
Ozawa, K1
Shimahara, Y1
Mori, K1
Kobayashi, N1
Kumada, K1
Yamaoka, Y1

Other Studies

5 other studies available for acetoacetic acid and Liver Dysfunction

ArticleYear
[Urinary excretion of p-oxyphenylpyruvic acid, pyruvic acid, phenol and diacetic acid following intake of p-oxyphenylpyruvic acid in the normal state and in liver disease].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1951, Volume: 287, Issue:3-6

    Topics: Acetoacetates; Humans; Liver Diseases; Phenol; Phenols; Pyruvic Acid; Urine

1951
A predominant increase of arterial beta-hydroxybutyrate concentration during partial hepatectomies in patients with impaired indocyanine green clearance test.
    The Journal of surgical research, 1999, Volume: 81, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Coloring Agents; Female; Hepatectomy; Hepatic Veins; Humans; I

1999
Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307.
    The Journal of surgical research, 1992, Volume: 53, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acute Disease; Adenosine Diphosphate; Adenosine Triphosphate;

1992
Hepatic dysoxia commences during O2 supply dependence.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 72, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Dogs; Hemorrhage; Hydroxybutyrates; Lactates; Lactic

1992
Diurnal fluctuations of arterial ketone body ratio in normal subjects and patients with liver dysfunction.
    Gastroenterology, 1991, Volume: 100, Issue:5 Pt 1

    Topics: Acetoacetates; Adult; Aged; Blood Glucose; Carcinoma, Hepatocellular; Chronic Disease; Circadian Rhy

1991