acetoacetic acid has been researched along with Diabetes Mellitus in 25 studies
acetoacetic acid : A 3-oxo monocarboxylic acid that is butyric acid bearing a 3-oxo substituent.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diabetes and alcohol abuse may cause severe metabolic disturbances that can be fatal." | 1.39 | Assessment of Traub formula and ketone bodies in cause of death investigations. ( Keltanen, T; Lindroos, K; Palo, JU; Partanen, T; Sajantila, A; Valonen, T, 2013) |
| "The mechanism by which ketosis causes accelerated cellular damage and vascular disease in diabetes is not known." | 1.30 | Ketosis (acetoacetate) can generate oxygen radicals and cause increased lipid peroxidation and growth inhibition in human endothelial cells. ( Jain, SK; Kannan, K; Lim, G, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (52.00) | 18.7374 |
| 1990's | 6 (24.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Salomón, T | 1 |
| Sibbersen, C | 1 |
| Hansen, J | 1 |
| Britz, D | 1 |
| Svart, MV | 1 |
| Voss, TS | 1 |
| Møller, N | 1 |
| Gregersen, N | 1 |
| Jørgensen, KA | 1 |
| Palmfeldt, J | 1 |
| Poulsen, TB | 1 |
| Johannsen, M | 1 |
| Abdurrachim, D | 1 |
| Teo, XQ | 1 |
| Woo, CC | 1 |
| Ong, SY | 1 |
| Salleh, NF | 1 |
| Lalic, J | 1 |
| Tan, RS | 1 |
| Lee, PTH | 1 |
| Keltanen, T | 1 |
| Sajantila, A | 1 |
| Palo, JU | 1 |
| Partanen, T | 1 |
| Valonen, T | 1 |
| Lindroos, K | 1 |
| Ramakrishnan, R | 1 |
| Sheeladevi, R | 1 |
| Namasivayam, A | 1 |
| Kalapos, MP | 1 |
| KRARUP, NB | 1 |
| WIELAND, O | 1 |
| LOEFFLER, G | 1 |
| WEISS, L | 1 |
| NEUFELDT, I | 1 |
| ELWOOD, JC | 2 |
| VAN BRUGGEN, JT | 2 |
| MARCO, A | 1 |
| NATH, MC | 2 |
| VAISHWANAR, I | 1 |
| CHAKRABARTI, CH | 1 |
| LEONHARDI, G | 1 |
| von GLASENAPP, I | 1 |
| Penders, J | 1 |
| Fiers, T | 1 |
| Giri, M | 1 |
| Wuyts, B | 1 |
| Ysewyn, L | 1 |
| Delanghe, JR | 1 |
| Deana, R | 1 |
| Lippe, G | 1 |
| Galzigna, L | 1 |
| Harano, Y | 1 |
| Kosugi, K | 1 |
| Hyosu, T | 1 |
| Uno, S | 1 |
| Ichikawa, Y | 1 |
| Shigeta, Y | 1 |
| Newrick, PG | 1 |
| Braatvedt, G | 1 |
| Stansbie, D | 1 |
| Corrall, RJ | 1 |
| Saeed, FA | 1 |
| Castle, GE | 1 |
| Jain, SK | 2 |
| Kannan, K | 1 |
| Lim, G | 2 |
| McVie, R | 1 |
| Jackson, R | 1 |
| Levine, SN | 1 |
| Barnett, CR | 1 |
| Flatt, PR | 1 |
| Ioannides, C | 1 |
| Massa, DJ | 1 |
| Molina, F | 1 |
| Valencia, MC | 1 |
| de la Torre, J | 1 |
| Capitán-Vallvey, LF | 1 |
| Nosadini, R | 2 |
| Avogaro, A | 2 |
| Trevisan, R | 2 |
| Duner, E | 1 |
| Marescotti, C | 1 |
| Iori, E | 1 |
| Cobelli, C | 2 |
| Toffolo, G | 2 |
| Kimura, M | 1 |
| Kobayashi, K | 1 |
| Matsuoka, A | 1 |
| Hayashi, K | 1 |
| Kimura, Y | 1 |
| Saccà, L | 1 |
| Vigorito, C | 1 |
| de Kreutzenberg, S | 1 |
| Tessari, P | 1 |
| Tiengo, A | 1 |
1 review available for acetoacetic acid and Diabetes Mellitus
| Article | Year |
|---|---|
On the mammalian acetone metabolism: from chemistry to clinical implications.
Topics: 2-Propanol; Acetoacetates; Acetone; Alcoholism; Carbon Dioxide; Diabetes Mellitus; Glucose; Humans; | 2003 |
1 trial available for acetoacetic acid and Diabetes Mellitus
| Article | Year |
|---|---|
Suppression of lipolysis in normal man does not inhibit recovery from insulin-induced hypoglycaemia.
Topics: Acetoacetates; Adult; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Fatty Acids, Noneste | 1993 |
23 other studies available for acetoacetic acid and Diabetes Mellitus
| Article | Year |
|---|---|
Ketone Body Acetoacetate Buffers Methylglyoxal via a Non-enzymatic Conversion during Diabetic and Dietary Ketosis.
Topics: Acetoacetates; Alkynes; Amino Acid Sequence; Chromatography, High Pressure Liquid; Diabetes Mellitus | 2017 |
Cardiac metabolic modulation upon low-carbohydrate low-protein ketogenic diet in diabetic rats studied in vivo using hyperpolarized
Topics: Acetoacetates; Animals; Blood Glucose; Butyrates; Carbon-13 Magnetic Resonance Spectroscopy; Cardiot | 2019 |
Assessment of Traub formula and ketone bodies in cause of death investigations.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Alcoholism; Algorithms; Autopsy; Biomarkers; Blood Gl | 2013 |
Regulation of protein kinases and coregulatory interplay of S-100beta and serotonin transporter on serotonin levels in diabetic rat brain.
Topics: Acetoacetates; Alloxan; Analysis of Variance; Animals; Blood Glucose; Brain; Carbonates; Diabetes Me | 2009 |
[Examination of the urine of diabetics for diacetic acid and acetone].
Topics: Acetoacetates; Acetone; Body Fluids; Diabetes Mellitus; Humans; Urine | 1956 |
[On acetoacetic acid and cholesterin formation in experimental ketosis].
Topics: Acetoacetates; Acidosis; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Experimental; Ketone Bod | 1960 |
Lipid metabolism in the diabetic rat. III. Acetate metabolism and acetoacetate synthesis in vitro.
Topics: Acetates; Acetoacetates; Animals; Diabetes Mellitus; In Vitro Techniques; Ketone Bodies; Lipid Metab | 1960 |
Lipid metabolism in the diabetic rat. IV. Metabolism of acetate, acetoacetate, butyrate, and mevalonate in vitro.
Topics: Acetates; Acetoacetates; Animals; Butyrates; Diabetes Mellitus; Fatty Acids; In Vitro Techniques; Ke | 1960 |
In vitro effect of hydrolysed glucose cyclo-acetoacetate on coagulation of blood in health and metabolic disorders.
Topics: Acetoacetates; Blood Coagulation; Coronary Disease; Diabetes Mellitus; Glucose; Humans; Hypertension | 1963 |
Progressive decreased glucose-tolerance and glycogen-storage following acetoacetate injection: prevention by insulin and amellin.
Topics: Acetoacetates; Carbohydrate Metabolism; Diabetes Mellitus; Glucose; Glycogen; Humans; Injections; In | 1950 |
[Detection and determination of acetoacetic acid in the urine].
Topics: Acetoacetates; Body Fluids; Diabetes Mellitus; Humans; Urine | 1951 |
Quantitative measurement of ketone bodies in urine using reflectometry.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adult; Diabetes Mellitus; Female; Humans; Insulin Inf | 2005 |
Urinary excretion of 3-hydroxy-3-methylglutaric acid in the diabetic condition.
Topics: Acetoacetates; Adult; Animals; Chromatography, Gas; Diabetes Mellitus; Diabetes Mellitus, Experiment | 1982 |
Sensitive and simplified method for the differential determination of serum levels of ketone bodies.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Diabetes Mellitus; Diazonium Compounds; Humans; Hydroxybutyrat | 1983 |
Neutrophil chemiluminescence during phagocytosis is inhibited by abnormally elevated levels of acetoacetate: implications for diabetic susceptibility to infections.
Topics: Acetoacetates; Diabetes Mellitus; Disease Susceptibility; Dose-Response Relationship, Drug; Humans; | 1998 |
Ketosis (acetoacetate) can generate oxygen radicals and cause increased lipid peroxidation and growth inhibition in human endothelial cells.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Cell Division; Cells, Cultured; Cytochrome c Group; Diabetes M | 1998 |
Effect of hyperketonemia on plasma lipid peroxidation levels in diabetic patients.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Di | 1999 |
Hyperketonaemia markedly modulates the metabolic activation of chemical carcinogens.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Biotransformation; Carcinogens; Cytochrome P-450 Enzy | 1990 |
Early diabetes detection?
Topics: Acetoacetates; Butyrates; Diabetes Mellitus; Household Products; Humans | 1990 |
Determination of acetoacetate in urine by solid-phase spectrophotometry.
Topics: Acetoacetates; Calibration; Diabetes Mellitus; Glycine; Humans; Hydrogen-Ion Concentration; Ions; Ke | 1989 |
Acetoacetate and 3-hydroxybutyrate kinetics in obese and insulin-dependent diabetic humans.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic | 1985 |
Head-space gas-chromatographic determination of 3-hydroxybutyrate in plasma after enzymic reactions, and the relationship among the three ketone bodies.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adolescent; Adult; Aged; Carboxy-Lyases; Chromatograp | 1985 |
Ketone body metabolism in normal and diabetic human skeletal muscle.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Carbon Radioisotopes; Diabetes Mellitus; Diabetes Melli | 1985 |