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acetoacetic acid and Alloxan Diabetes

acetoacetic acid has been researched along with Alloxan Diabetes in 40 studies

acetoacetic acid : A 3-oxo monocarboxylic acid that is butyric acid bearing a 3-oxo substituent.

Research Excerpts

ExcerptRelevanceReference
"To elucidate the peripheral disposal of ketone bodies in hyperketonemia accompanied with starvation, hyperthyroidism, or diabetes mellitus, the uptake of acetoacetic acid (AcAc) and beta-hydroxybutyrate (BOHB) was investigated in the perfused hindquarter and kidney of starved, thyrotoxic, and diabetic rats."3.68Uptake of ketone bodies in perfused hindquarter and kidney of starved, thyrotoxic, and diabetic rats. ( Fujiyama, K; Hoshino, T; Ikeda, T; Ishimura, M; Mashiba, H; Ochi, H; Ohtani, I; Tanaka, Y; Terasawa, H, 1993)
"Glycerol was the best substrate for D-lactate formation via methylglyoxal in rat liver."1.29Carbon sources for D-lactate formation in rat liver. ( Hirata, M; Kawase, M; Kondoh, Y; Ohmori, S, 1994)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199025 (62.50)18.7374
1990's12 (30.00)18.2507
2000's1 (2.50)29.6817
2010's2 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdurrachim, D1
Woo, CC1
Teo, XQ1
Chan, WX1
Radda, GK1
Lee, PTH1
Zhao, L1
Liu, X1
Xie, L1
Gao, H1
Lin, D1
Uehara, Y1
Engel, T1
Li, Z1
Goepfert, C1
Rust, S1
Zhou, X1
Langer, C1
Schachtrup, C1
Wiekowski, J1
Lorkowski, S1
Assmann, G1
von Eckardstein, A1
NATH, MC8
GADGIL, JS1
HATWALNE, VG1
HELMREICH, E1
HOLZER, H1
LAMPRECHT, W1
GOLDSCHMIDT, S1
SAHU, VK2
BHATTATHIRY, EP2
BEHKI, RM3
ROSSI, F1
ROSSI, CR1
ROSSI, CS1
BEATTY, CH2
PETERSON, RD2
BOCEK, RM2
WEST, ES2
ESER, S2
TEKMAN, S2
ARAZ, A2
MARCO, A1
MOREY, KS1
BRAHMANKAR, DM1
OHNEDA, A1
WIELAND, O1
LOEFFLER, G1
WEISS, L1
NEUFELDT, I1
Deana, R1
Lippe, G1
Galzigna, L1
Ohgaku, S2
Brady, PS2
Schumann, WC2
Bartsch, GE2
Margolis, JM2
Kumaran, K2
Landau, SB1
Landau, BR2
Scofield, RF1
Horvat, A1
Mann, S1
Kielducka, A1
Paradies, G1
Papa, S1
Shin, M1
Maeda, S1
Hashimoto, Y1
Sano, K1
Umezawa, C1
Sultan, AM2
Kondoh, Y1
Kawase, M1
Hirata, M1
Ohmori, S1
Moley, KH1
Vaughn, WK1
Diamond, MP1
Gibson, R1
Zhao, Y1
Jaskiewicz, J1
Fineberg, SE1
Harris, RA1
Hotta, N1
Komori, T1
Kobayashi, M1
Sakakibara, F1
Koh, N1
Sakamoto, N1
Ikeda, T2
Ishimura, M1
Terasawa, H1
Ochi, H1
Ohtani, I2
Fujiyama, K2
Hoshino, T2
Tanaka, Y2
Mashiba, H2
Rodríguez, T1
Busquets, S1
Alvarez, B1
Agell, N1
Lpez-Soriano, FJ1
Argilś, JM1
Takeuchi, T1
Bailey, JW1
Haymond, MW1
Miles, JM1
Avogaro, A1
Nosadini, R1
Doria, A1
Tremolada, C1
Baccaglini, U1
Ambrosio, F1
Merkel, C1
Nosadini, A1
Trevisan, R1
Fioretto, P1
Hawkins, RA1
Mans, AM1
Davis, DW1
Okuda, Y1
Kawai, K1
Yamashita, K1
Grantham, BD1
Zammit, VA1
Freed, LE1
Endemann, G1
Tomera, JF1
Gavino, VC1
Brunengraber, H1
Zusman, I1
Yaffe, P1
Ornoy, A1

Other Studies

40 other studies available for acetoacetic acid and Alloxan Diabetes

ArticleYear
A new hyperpolarized
    Scientific reports, 2019, 04-02, Volume: 9, Issue:1

    Topics: Acetoacetates; Animals; Carbon-13 Magnetic Resonance Spectroscopy; Cardiomegaly; Diabetes Mellitus,

2019
1H NMR-based metabonomic analysis of metabolic changes in streptozotocin-induced diabetic rats.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2010, Volume: 26, Issue:12

    Topics: Acetoacetates; Animals; Diabetes Mellitus, Experimental; Fatty Acids; Liver Extracts; Magnetic Reson

2010
Polyunsaturated fatty acids and acetoacetate downregulate the expression of the ATP-binding cassette transporter A1.
    Diabetes, 2002, Volume: 51, Issue:10

    Topics: Acetoacetates; Animals; Carcinoma, Hepatocellular; Cholesterol, HDL; Diabetes Mellitus, Experimental

2002
Studies on alloxan diabetes. I. Increase of susceptibility caused by acetoacetate.
    The Biochemical journal, 1953, Volume: 53, Issue:3

    Topics: Acetoacetates; Animals; Diabetes Mellitus, Experimental; Disease Susceptibility

1953
[Determination of stationary concentrations of intermediate substances. II. Origin of ketone bodies and their relation to glycolysis].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1954, Volume: 297, Issue:3-6

    Topics: Acetoacetates; Animals; Body Fluids; Diabetes Mellitus, Experimental; Fasting; Glycolysis; Humans; K

1954
Prevention of alloxan diabetes by a condensation product of glucose and acetoacetate. I.
    Metabolism: clinical and experimental, 1956, Volume: 5, Issue:1

    Topics: Acetoacetates; Animals; Diabetes Mellitus, Experimental; Glucose

1956
Prevention of alloxan diabetes by a condensation product of glucose and acetoacetate. II.
    Metabolism: clinical and experimental, 1956, Volume: 5, Issue:1

    Topics: Acetoacetates; Animals; Diabetes Mellitus, Experimental; Glucose

1956
Prevention of dehydroascorbic acid diabetes by the sodium salt of the condensation product of glucose and acetoacetate.
    Metabolism: clinical and experimental, 1956, Volume: 5, Issue:1

    Topics: Acetoacetates; Animals; Ascorbic Acid; Biomedical Research; Dehydroascorbic Acid; Diabetes Mellitus,

1956
Further studies on the prevention of dehydroascorbic acid diabetes by the condensation product of glucose and acetoacetate.
    Metabolism: clinical and experimental, 1957, Volume: 6, Issue:2

    Topics: Acetoacetates; Animals; Ascorbic Acid; Biomedical Research; Dehydroascorbic Acid; Diabetes Mellitus,

1957
[Respiratory exchange and acetoacetic acid metabolism in liver in alloxan diabetic rats].
    Experientia, 1957, Aug-15, Volume: 13, Issue:8

    Topics: Acetoacetates; Alloxan; Animals; Diabetes Mellitus, Experimental; Lipid Metabolism; Liver; Rats

1957
Prevention of acetoacetate-induced diabetes by the condensation product of glucose and acetoacetate and its sparing effect on blood GSH.
    Archives of biochemistry and biophysics, 1958, Volume: 73, Issue:1

    Topics: Acetoacetates; Animals; Diabetes Mellitus, Experimental; Glucose; Glutathione

1958
Acetoacetate and glucose uptake by diaphragm and skeletal muscle from from control and diabetic rats.
    The Journal of biological chemistry, 1959, Volume: 234, Issue:1

    Topics: Acetoacetates; Animals; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Diaphragm; Glucose

1959
[Effects of nicotinamide on ketone metabolism by liver of alloxan diabetic rats in vitro. II. Study of acetoacetate utilization by distillation method].
    Tip Fakultesi mecmuasi, 1958, Volume: 21, Issue:3

    Topics: Acetoacetates; Alloxan; Animals; Diabetes Mellitus, Experimental; Distillation; In Vitro Techniques;

1958
[Effects of nicotinamide on ketone metabolism by liver of aloxan diabetic rats in vitro. III. Study of acetoacetate utilization by colorimetric method].
    Tip Fakultesi mecmuasi, 1958, Volume: 21, Issue:3

    Topics: Acetoacetates; Animals; Colorimetry; Diabetes Mellitus, Experimental; In Vitro Techniques; Liver; Ni

1958
Cure of alloxan diabetes by combined therapy with glucose-cyclo-acetoacetate and estrogen.
    Metabolism: clinical and experimental, 1959, Volume: 8, Issue:2

    Topics: Acetoacetates; Animals; Diabetes Mellitus, Experimental; Estrogens; Glucose

1959
Acetoacetic acid metabolism by skeletal muscle fibers from control and diabetic rats.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Acetoacetates; Animals; Diabetes Mellitus, Experimental; Ketone Bodies; Muscle Fibers, Skeletal; Mus

1960
Disturbances in serum protein pattern in acetoacetate induced diabetes: prevention by glucose cyclo-acetoacetate.
    Annals of biochemistry and experimental medicine, 1961, Volume: 21

    Topics: Acetoacetates; Animals; Blood Proteins; Diabetes Mellitus, Experimental; Glucose; Humans; Ketone Bod

1961
On the pituitary-adrenal system in the rats with the administration of acetoacetate.
    The Tohoku journal of experimental medicine, 1960, Sep-25, Volume: 72

    Topics: Acetoacetates; Adrenal Glands; Animals; Carbohydrate Metabolism; Carbohydrates; Diabetes Mellitus, E

1960
[On acetoacetic acid and cholesterin formation in experimental ketosis].
    Biochemische Zeitschrift, 1960, Volume: 333

    Topics: Acetoacetates; Acidosis; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Experimental; Ketone Bod

1960
Urinary excretion of 3-hydroxy-3-methylglutaric acid in the diabetic condition.
    Clinical biochemistry, 1982, Volume: 15, Issue:2

    Topics: Acetoacetates; Adult; Animals; Chromatography, Gas; Diabetes Mellitus; Diabetes Mellitus, Experiment

1982
A method for quantitating the contributions of the pathways of acetoacetate formation and its application to diabetic ketosis in vivo.
    The Journal of biological chemistry, 1982, Aug-25, Volume: 257, Issue:16

    Topics: Acetoacetates; Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chemical Phenomena; Chemistry; Diabetes

1982
Pathways of acetoacetate's formation in liver and kidney.
    The Journal of biological chemistry, 1982, Aug-25, Volume: 257, Issue:16

    Topics: Acetoacetates; Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chemical Phenomena; Chemistry; Diabetes

1982
A comparative study of the transport of pyruvate in liver mitochondria from normal and diabetic rats.
    Journal of bioenergetics and biomembranes, 1981, Volume: 13, Issue:3-4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Biological Transport; Blood Glucose; Diabetes Mellitu

1981
NAD synthesis from nicotinic acid by the hepatocytes prepared from diabetic rats.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1995, Volume: 65, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Carbon Radioisotopes; Cells, Cultured;

1995
The effects of chronic diabetes and physiological insulin concentration on ketone bodies metabolism in the heart.
    Diabetes research (Edinburgh, Scotland), 1994, Volume: 27, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Diabetes Mellitus, Experimental; Dose-Response Relati

1994
Carbon sources for D-lactate formation in rat liver.
    Journal of biochemistry, 1994, Volume: 115, Issue:3

    Topics: Acetoacetates; Acetone; Animals; Diabetes Mellitus, Experimental; Glucose; Glycerol; In Vitro Techni

1994
Manifestations of diabetes mellitus on mouse preimplantation development: effect of elevated concentration of metabolic intermediates.
    Human reproduction (Oxford, England), 1994, Volume: 9, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids; Animals; Butyrates; Cleavage Stage, Ovum; Culture

1994
Effects of diabetes on the activity and content of the branched-chain alpha-ketoacid dehydrogenase complex in liver.
    Archives of biochemistry and biophysics, 1993, Volume: 306, Issue:1

    Topics: 3-Hydroxybutyric Acid; 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acetoacetates; Animals; Bl

1993
The inhibitory action of buformin, a biguanide on gluconeogenesis from alanine and its transport system in rat livers.
    Diabetes research and clinical practice, 1993, Volume: 19, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Animals; Biological Transport, Active; Buformin; Cell

1993
Uptake of ketone bodies in perfused hindquarter and kidney of starved, thyrotoxic, and diabetic rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1993, Volume: 203, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Triphosphate; Animals; Biological Transport; Diabete

1993
Protein turnover in skeletal muscle of the diabetic rat: activation of ubiquitin-dependent proteolysis.
    International journal of molecular medicine, 1998, Volume: 1, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adipose Tissue; Animals; Body Weight; Diabetes Mellitus, Exper

1998
Effects of diabetes and insulin on ketone bodies metabolism in heart.
    Molecular and cellular biochemistry, 1992, Mar-04, Volume: 110, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Diabetes Mellitus, Experimental; Hydroxybutyrates; In

1992
Uptake of beta-hydroxybutyrate in perfused hindquarter of starved and diabetic rats.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:12

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Diabetes Mellitus, Experimental; Glucose; Hindlimb; H

1991
Validation of two-pool model for in vivo ketone body kinetics.
    The American journal of physiology, 1990, Volume: 258, Issue:5 Pt 1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Carbon Isotopes; Carbon Radioisotopes; Diabetes Melli

1990
Substrate availability other than glucose in the brain during euglycemia and insulin-induced hypoglycemia in dogs.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Brain; Diabetes Mellitus, Experimental

1990
Regional ketone body utilization by rat brain in starvation and diabetes.
    The American journal of physiology, 1986, Volume: 250, Issue:2 Pt 1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Autoradiography; Brain; Diabetes Mellitus, Experiment

1986
Age-related change in ketone body metabolism: diminished glucagon effect on ketogenesis in adult rats.
    Endocrinology, 1987, Volume: 120, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Carnitine; Cyclic AMP; Diabetes Mellitus, Expe

1987
Role of carnitine palmitoyltransferase I in the regulation of hepatic ketogenesis during the onset and reversal of chronic diabetes.
    The Biochemical journal, 1988, Jan-15, Volume: 249, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acyltransferases; Animals; Blood Glucose; Carnitine O-Palmitoy

1988
Lipogenesis from ketone bodies in perfused livers from streptozocin-induced diabetic rats.
    Diabetes, 1988, Volume: 37, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Coenzyme A Ligases; Diabetes Mellitus, Experimental;

1988
Effects of metabolic factors in the diabetic state on the in vitro development of preimplantation mouse embryos.
    Teratology, 1987, Volume: 35, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blastocyst; Culture Techniques; Diabetes Mellitus, Ex

1987