acetoacetic acid has been researched along with Acidosis, Diabetic in 28 studies
acetoacetic acid : A 3-oxo monocarboxylic acid that is butyric acid bearing a 3-oxo substituent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A complication of diabetes is diabetic ketoacidosis (DKA), which if left untreated is a life threatening condition." | 2.53 | Evaluation of the Accuracy of Capillary Hydroxybutyrate Measurement Compared with Other Measurements in the Diagnosis of Diabetic Ketoacidosis: A Systematic Review. ( Brooke, J; Ojo, O; Stiell, M, 2016) |
| "Diabetic ketoacidosis is a life-threatening complication of Type 1 diabetes." | 2.49 | Blood β-hydroxybutyrate vs. urine acetoacetate testing for the prevention and management of ketoacidosis in Type 1 diabetes: a systematic review. ( Craig, ME; Klocker, AA; Phelan, H; Twigg, SM, 2013) |
| "Outcomes examined were prevention of diabetic ketoacidosis, time to recovery from diabetic ketoacidosis, healthcare costs and patient or caregiver satisfaction." | 2.49 | Blood β-hydroxybutyrate vs. urine acetoacetate testing for the prevention and management of ketoacidosis in Type 1 diabetes: a systematic review. ( Craig, ME; Klocker, AA; Phelan, H; Twigg, SM, 2013) |
| "No study assessed prevention of diabetic ketoacidosis." | 2.49 | Blood β-hydroxybutyrate vs. urine acetoacetate testing for the prevention and management of ketoacidosis in Type 1 diabetes: a systematic review. ( Craig, ME; Klocker, AA; Phelan, H; Twigg, SM, 2013) |
| "Severe hypertriglyceridemia was considered to have been a consequence of impaired insulin action and his apolipoprotein E4/2 phenotype." | 1.51 | Eruptive xanthomas in a patient with soft-drink diabetic ketosis and apolipoprotein E4/2. ( Aiba, S; Imai, J; Katagiri, H; Kikuchi, K; Kohata, M; Kurosawa, S; Nakajima, T; Satake, C; Sawada, S; Takahashi, K; Takeda, K; Tsuchiya, S, 2019) |
| "Soft-drink diabetic ketosis, characterized by acute onset ketosis induced by excessive ingestion of sugar-containing drinks, is often seen in obese, young patients, even with undiagnosed type 2 diabetes." | 1.51 | Eruptive xanthomas in a patient with soft-drink diabetic ketosis and apolipoprotein E4/2. ( Aiba, S; Imai, J; Katagiri, H; Kikuchi, K; Kohata, M; Kurosawa, S; Nakajima, T; Satake, C; Sawada, S; Takahashi, K; Takeda, K; Tsuchiya, S, 2019) |
| "The eruptive xanthoma lesions gradually diminished in size and number and eventually disappeared by 12 months." | 1.51 | Eruptive xanthomas in a patient with soft-drink diabetic ketosis and apolipoprotein E4/2. ( Aiba, S; Imai, J; Katagiri, H; Kikuchi, K; Kohata, M; Kurosawa, S; Nakajima, T; Satake, C; Sawada, S; Takahashi, K; Takeda, K; Tsuchiya, S, 2019) |
| "Diabetes and alcohol abuse may cause severe metabolic disturbances that can be fatal." | 1.39 | Assessment of Traub formula and ketone bodies in cause of death investigations. ( Keltanen, T; Lindroos, K; Palo, JU; Partanen, T; Sajantila, A; Valonen, T, 2013) |
| "Type 1 diabetes is associated with elevated levels of blood PAI-1 and cardiovascular disease (CVD) incidence." | 1.37 | Effects of high glucose and ketosis (acetoacetate, ss-hydroxybutyrate) on PAI-1 secretion in human umbilical vascular endothelial cells. ( Jain, SK; Velusamy, T, 2011) |
| "During diabetic ketoacidosis (DKA), serum ketone concentrations markedly increase; however, little is known about whether ketone bodies accumulate in cerebral tissues during DKA." | 1.33 | Detection of cerebral {beta}-hydroxy butyrate, acetoacetate, and lactate on proton MR spectroscopy in children with diabetic ketoacidosis. ( Barnes, PD; Buonocore, MH; Dicarlo, J; Glaser, N; Kuppermann, N; Marcin, J; Neely, EK; Wootton-Gorges, SL, 2005) |
| "An emaciated patient suffering from Duchenne Muscular Dystrophy and volume depletion presented with acidosis of unknown origin." | 1.33 | Unexplained acidosis of malnutrition: a study by ion-exchange chromatography/mass spectrometry. ( Forni, LG; Hilton, PJ; Lord, GA; McKinnon, W; Peron, JM, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (21.43) | 18.7374 |
| 1990's | 3 (10.71) | 18.2507 |
| 2000's | 11 (39.29) | 29.6817 |
| 2010's | 8 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heimer, J | 1 |
| Gascho, D | 1 |
| Chatzaraki, V | 1 |
| Knaute, DF | 1 |
| Sterzik, V | 1 |
| Martinez, RM | 1 |
| Thali, MJ | 1 |
| Zoelch, N | 1 |
| Polidori, D | 1 |
| Iijima, H | 1 |
| Goda, M | 1 |
| Maruyama, N | 1 |
| Inagaki, N | 1 |
| Crawford, PA | 1 |
| Tsuchiya, S | 1 |
| Sawada, S | 1 |
| Takeda, K | 1 |
| Takahashi, K | 1 |
| Nakajima, T | 1 |
| Kohata, M | 1 |
| Kurosawa, S | 1 |
| Satake, C | 1 |
| Imai, J | 1 |
| Kikuchi, K | 1 |
| Aiba, S | 1 |
| Katagiri, H | 1 |
| Keltanen, T | 1 |
| Sajantila, A | 1 |
| Palo, JU | 1 |
| Partanen, T | 1 |
| Valonen, T | 1 |
| Lindroos, K | 1 |
| Akram, M | 1 |
| Brooke, J | 1 |
| Stiell, M | 1 |
| Ojo, O | 1 |
| Velusamy, T | 1 |
| Jain, SK | 3 |
| Klocker, AA | 1 |
| Phelan, H | 1 |
| Twigg, SM | 1 |
| Craig, ME | 1 |
| Harano, Y | 1 |
| Hoffman, WH | 1 |
| Cheng, C | 1 |
| Passmore, GG | 1 |
| Carroll, JE | 1 |
| Hess, D | 1 |
| Kannan, K | 1 |
| Lim, G | 2 |
| Matthews-Greer, J | 1 |
| McVie, R | 2 |
| Bocchini, JA | 1 |
| Khan, AS | 1 |
| Talbot, JA | 1 |
| Tieszen, KL | 1 |
| Gardener, EA | 1 |
| Gibson, JM | 1 |
| New, JP | 1 |
| Taboulet, P | 1 |
| Haas, L | 1 |
| Porcher, R | 1 |
| Manamani, J | 1 |
| Fontaine, JP | 1 |
| Feugeas, JP | 1 |
| Gautier, JF | 1 |
| Royer, LO | 1 |
| Knudsen, FS | 1 |
| de Oliveira, MA | 1 |
| Tavares, MF | 1 |
| Bechara, EJ | 1 |
| Wootton-Gorges, SL | 1 |
| Buonocore, MH | 1 |
| Kuppermann, N | 1 |
| Marcin, J | 1 |
| Dicarlo, J | 1 |
| Neely, EK | 1 |
| Barnes, PD | 1 |
| Glaser, N | 1 |
| Ramakrishnan, R | 1 |
| Sheeladevi, R | 1 |
| Suthanthirarajan, N | 1 |
| Namasivayam, A | 1 |
| Corey, HE | 1 |
| Prisco, F | 1 |
| Picardi, A | 1 |
| Iafusco, D | 1 |
| Lorini, R | 1 |
| Minicucci, L | 1 |
| Martinucci, ME | 1 |
| Toni, S | 1 |
| Cerutti, F | 1 |
| Rabbone, I | 1 |
| Buzzetti, R | 1 |
| Crino, A | 1 |
| Pozzilli, P | 1 |
| Hilton, PJ | 1 |
| McKinnon, W | 1 |
| Lord, GA | 1 |
| Peron, JM | 1 |
| Forni, LG | 1 |
| Hall, SE | 1 |
| Wastney, ME | 1 |
| Bolton, TM | 1 |
| Braaten, JT | 1 |
| Berman, M | 1 |
| Ohgaku, S | 2 |
| Brady, PS | 2 |
| Schumann, WC | 2 |
| Bartsch, GE | 2 |
| Margolis, JM | 2 |
| Kumaran, K | 2 |
| Landau, SB | 1 |
| Landau, BR | 2 |
| Scofield, RF | 1 |
| Horvat, A | 1 |
| Mann, S | 1 |
| Quin, JD | 1 |
| Smith, K | 1 |
| Beastall, GH | 1 |
| Miell, JP | 1 |
| MacCuish, AC | 1 |
| Avogaro, A | 2 |
| Crepaldi, C | 1 |
| Piarulli, F | 1 |
| Milan, D | 1 |
| Valerio, A | 1 |
| Pavan, P | 1 |
| Sacerdoti, D | 1 |
| Calabrò, A | 1 |
| Macdonald, I | 1 |
| Crepaldi, G | 1 |
| Scognamiglio, R | 1 |
| Tiengo, A | 1 |
| Jackson, R | 1 |
| Levine, SN | 1 |
| Nuwayhid, NF | 1 |
| Johnson, GF | 1 |
| Feld, RD | 1 |
| Féry, F | 1 |
| Balasse, EO | 1 |
| Nosadini, R | 1 |
| Trevisan, R | 1 |
| Duner, E | 1 |
| Marescotti, C | 1 |
| Iori, E | 1 |
| Cobelli, C | 1 |
| Toffolo, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Development of Ketoacidosis During the Perioperative Period: an Observational Study 'The DKAP Study'[NCT05225467] | 58 participants (Actual) | Observational [Patient Registry] | 2022-03-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for acetoacetic acid and Acidosis, Diabetic
| Article | Year |
|---|---|
A focused review of the role of ketone bodies in health and disease.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Alzheimer Disease; Blood Glucose; Diabetic Ketoacidos | 2013 |
Evaluation of the Accuracy of Capillary Hydroxybutyrate Measurement Compared with Other Measurements in the Diagnosis of Diabetic Ketoacidosis: A Systematic Review.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Dia | 2016 |
Blood β-hydroxybutyrate vs. urine acetoacetate testing for the prevention and management of ketoacidosis in Type 1 diabetes: a systematic review.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Critical Care; Crown-Rump Length; Diabetes Mellitus, Type 1; D | 2013 |
[Blood level of ketone bodies and its clinical significance].
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 2002 |
2 trials available for acetoacetic acid and Acidosis, Diabetic
| Article | Year |
|---|---|
Intra- and inter-subject variability for increases in serum ketone bodies in patients with type 2 diabetes treated with the sodium glucose co-transporter 2 inhibitor canagliflozin.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Biological Variation, Population; Blood Glucose; Canagliflozin | 2018 |
The hemodynamic abnormalities in short-term insulin deficiency: the role of prostaglandin inhibition.
Topics: 3-Hydroxybutyric Acid; 6-Ketoprostaglandin F1 alpha; Acetoacetates; Adult; Blood Glucose; Diabetes M | 1996 |
22 other studies available for acetoacetic acid and Acidosis, Diabetic
| Article | Year |
|---|---|
Postmortem
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adult; Diabetic Ketoacidosis; Glucose; Humans; Ketone | 2018 |
Eruptive xanthomas in a patient with soft-drink diabetic ketosis and apolipoprotein E4/2.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adolescent; Apolipoprotein E2; Apolipoprotein E4; Carbonated B | 2019 |
Assessment of Traub formula and ketone bodies in cause of death investigations.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Alcoholism; Algorithms; Autopsy; Biomarkers; Blood Gl | 2013 |
Effects of high glucose and ketosis (acetoacetate, ss-hydroxybutyrate) on PAI-1 secretion in human umbilical vascular endothelial cells.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetic Ketoacido | 2011 |
Acetoacetate increases expression of intercellular adhesion molecule-1 (ICAM-1) in human brain microvascular endothelial cells.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Brain; Cells, Cultured; Diabetic Ketoacidosis; Dose-Response R | 2002 |
Elevated blood interleukin-6 levels in hyperketonemic type 1 diabetic patients and secretion by acetoacetate-treated cultured U937 monocytes.
Topics: Acetoacetates; Adolescent; Age of Onset; Cells, Cultured; Child; Diabetes Mellitus, Type 1; Diabetic | 2003 |
Evaluation of a bedside blood ketone sensor: the effects of acidosis, hyperglycaemia and acetoacetate on sensor performance.
Topics: Acetoacetates; Acidosis; Biosensing Techniques; Blood Glucose; Blood Glucose Self-Monitoring; Diabet | 2004 |
Urinary acetoacetate or capillary beta-hydroxybutyrate for the diagnosis of ketoacidosis in the Emergency Department setting.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Biomarkers; Capillaries; Critical Illness; Diabetic Ketoacidos | 2004 |
Peroxynitrite-initiated oxidation of acetoacetate and 2-methylacetoacetate esters by oxygen: potential sources of reactive intermediates in keto acidoses.
Topics: Acetoacetates; Diabetic Ketoacidosis; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen- | 2004 |
Detection of cerebral {beta}-hydroxy butyrate, acetoacetate, and lactate on proton MR spectroscopy in children with diabetic ketoacidosis.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Child; Diabetic Ketoacidosis; Female; Humans; Lactic Acid; Mag | 2005 |
An acute hyperglycemia or acidosis-induced changes of indolamines level correlates with PKC-alpha expression in rat brain.
Topics: Acetoacetates; Ammonium Chloride; Animals; Brain; Brain Chemistry; Diabetes Complications; Diabetic | 2005 |
The anion gap (AG): studies in the nephrotic syndrome and diabetic ketoacidosis (DKA).
Topics: Acetoacetates; Acid-Base Equilibrium; Adolescent; Adult; Anions; Child; Child, Preschool; Diabetes M | 2006 |
Blood ketone bodies in patients with recent-onset type 1 diabetes (a multicenter study).
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes M | 2006 |
Unexplained acidosis of malnutrition: a study by ion-exchange chromatography/mass spectrometry.
Topics: Acetoacetates; Acidosis; Adolescent; Chromatography, High Pressure Liquid; Chromatography, Ion Excha | 2006 |
Ketone body kinetics in humans: the effects of insulin-dependent diabetes, obesity, and starvation.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adolescent; Adult; Diabetes Mellitus, Type 1; Diabetic Ketoaci | 1984 |
A method for quantitating the contributions of the pathways of acetoacetate formation and its application to diabetic ketosis in vivo.
Topics: Acetoacetates; Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chemical Phenomena; Chemistry; Diabetes | 1982 |
Pathways of acetoacetate's formation in liver and kidney.
Topics: Acetoacetates; Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chemical Phenomena; Chemistry; Diabetes | 1982 |
The effect of recombinant insulin-like growth factor I on ketone body, lipid and apolipoprotein concentrations and its use to treat ketoacidosis in severe insulin resistance.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adolescent; Apolipoproteins; Diabetic Ketoacidosis; Humans; Hy | 1994 |
Effect of hyperketonemia on plasma lipid peroxidation levels in diabetic patients.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Di | 1999 |
Kinetic measurement of the combined concentrations of acetoacetate and beta-hydroxybutyrate in serum.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Catalysis; Diabetic Ketoacidosis; Female; Humans; Hydro | 1988 |
Ketone body production and disposal in diabetic ketosis. A comparison with fasting ketosis.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Adolescent; Adult; Diabetes Mellitus, Type 1; Diabet | 1985 |
Acetoacetate and 3-hydroxybutyrate kinetics in obese and insulin-dependent diabetic humans.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic | 1985 |