Page last updated: 2024-10-16

acetic acid and Ulcer

acetic acid has been researched along with Ulcer in 24 studies

Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.

Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.

Research Excerpts

ExcerptRelevanceReference
" major in rats with acetic acid-induced ulcerative colitis (UC)."8.12Evaluation of anti-inflammatory effects of leaf and seed extracts of Plantago major on acetic acid-induced ulcerative colitis in rats. ( Farid, A; Motevalian, M; Noori, M; Sheibani, M; Shojaii, A, 2022)
"We investigated the effect of chronic alcohol ingestion on buccal mucosal ulcer healing by analyzing the interplay between mucosal expression of tumor necrosis factor-alpha (TNF-alpha), endothelin-1 (ET-1), and interleukin-4 (IL-4)."7.70Role of endothelin-1 and interleukin-4 in buccal mucosal ulcer healing: effect of chronic alcohol ingestion. ( Piotrowski, J; Slomiany, A; Slomiany, BL, 1999)
"In our study we have tried to compare the prophylactic effects of superoxide dismutase (SOD), SOD+catalase (CAT), desferrioxamine, verapamil and disulfiram, which are all free oxygen radical (FOR) scavengers, in an animal model of experimental acetic acid colitis."7.69The prophylactic effects of superoxide dismutase, catalase, desferrioxamine, verapamil and disulfiram in experimental colitis. ( Cokneşelí, B; Köksoy, FN; Köse, H; Soybír, GR; Yalçin, O, 1997)
"The effect of subcutaneous and luminal epidermal growth factor (EGF) administration on acetic acid-induced colonic ulceration was determined in adult rats."7.69Effects of epidermal growth factor administration on repair of acetic acid-induced colonic ulcerations in rats. ( Bourne, AJ; Ford, WD; George-Nascimento, C; Howarth, GS; Read, LC; Ribbons, KA, 1997)
"We studied the healing of acetic acid-induced esophageal ulcers in rats with respect to the cellular kinetics."7.67Healing process of experimental esophageal ulcers induced by acetic acid in rats. ( Fujino, H; Fuse, Y; Kawamoto, K; Kodama, T; Tsuji, H, 1989)
"major in rats with acetic acid-induced ulcerative colitis (UC)."5.72Evaluation of anti-inflammatory effects of leaf and seed extracts of Plantago major on acetic acid-induced ulcerative colitis in rats. ( Farid, A; Motevalian, M; Noori, M; Sheibani, M; Shojaii, A, 2022)
"Ulcers were induced by serosal application of 80 % acetic acid to the stomach of rats anaesthetized with 50 mg/kg thiopentone sodium and treatment was given three times daily."5.46Effects of quinine on gastric ulcer healing in Wistar rats. ( Adeniyi, OS; Friday, ET; Makinde, OV; Olaleye, SB, 2017)
" Here, we investigated gene modulation in the trigeminal ganglion and intraoral pain-related behavior in a rat model of acetic acid-induced oral ulcerative mucositis."4.31Hepcidin expression in the trigeminal ganglion and the oral mucosa in an oral ulcerative mucositis rat model. ( Hitomi, S; Kokabu, S; Nakatomi, C; Nodai, T; Omiya, Y; Ono, K; Sago-Ito, M; Shikayama, T; Shinoda, M; Terawaki, K, 2023)
" major in rats with acetic acid-induced ulcerative colitis (UC)."4.12Evaluation of anti-inflammatory effects of leaf and seed extracts of Plantago major on acetic acid-induced ulcerative colitis in rats. ( Farid, A; Motevalian, M; Noori, M; Sheibani, M; Shojaii, A, 2022)
"Rats (females) were treated with AEC (3, 30 or 300 mg/kg) prior to the ethanol or piroxicam-induced gastric ulcers."4.12Gastroprotective and gastric healing effects of the aqueous extract of Casearia sylvestris in rodents: Ultrasound, histological and biochemical analyzes. ( Aires, BA; Boeing, T; Cury, BJ; da Costa Zanatta, ME; de Oliveira, BMM; Dos Santos, AC; Mota da Silva, L; Roman Junior, WA; Serpa, PZ; Somensi, LB; Steffler, AM; Venzon, L, 2022)
"The AEC (30 or 300 mg/kg) prevented ulcers in the ethanol- and piroxicam-induced acute."4.12Gastroprotective and gastric healing effects of the aqueous extract of Casearia sylvestris in rodents: Ultrasound, histological and biochemical analyzes. ( Aires, BA; Boeing, T; Cury, BJ; da Costa Zanatta, ME; de Oliveira, BMM; Dos Santos, AC; Mota da Silva, L; Roman Junior, WA; Serpa, PZ; Somensi, LB; Steffler, AM; Venzon, L, 2022)
"Esophageal ulcers were induced in rats by topical exposure of the lower esophageal serosa to acetic acid, followed by intraperitoneal administration of HGF (200 µg/day) using an osmotic pump for 7 days."3.91Hepatocyte Growth Factor Facilitates Esophageal Mucosal Repair and Inhibits the Submucosal Fibrosis in a Rat Model of Esophageal Ulcer. ( Arima, S; Hashimoto, S; Ido, A; Kanmura, S; Komaki, Y; Maeda, H; Mawatari, S; Nasu, Y; Oda, K; Sasaki, F; Tanoue, S; Tsubouchi, H, 2019)
"CL improved body weight gain, mean macroscopic and microscopic ulcer scores in the colon of rats suffering from acetic acid-induced IBD."3.83Effect of turmeric on colon histology, body weight, ulcer, IL-23, MPO and glutathione in acetic-acid-induced inflammatory bowel disease in rats. ( Adeghate, E; Al Ahmed, MM; Al Zaabi, A; Amir, N; Bastaki, SMA, 2016)
"Oesophageal ulcers were induced in rats with acetic acid and subsequently treated by local injection of plasmids expressing either SRF or SRF antisense sequence."3.74A critical role of serum response factor in myofibroblast differentiation during experimental oesophageal ulcer healing in rats. ( Chai, J; Chow, J; Norng, M; Tarnawski, AS, 2007)
" In acetic acid-induced colitis in the rat, levels of malondialdehyde were found to be more markedly reduced with MED15 than with 5-aminosalicylic acid."3.72Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug. ( Belogi, L; Bettelli, E; Mezzadri, CM; Tubaro, E, 2003)
" In in vivo indomethacin-induced rat ileitis, MED15 heals better than 5-aminosalicylic acid and sulfasalazine, as well as down-regulating intestinal wall myeloperoxidase content."3.72Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug. ( Belogi, L; Bettelli, E; Mezzadri, CM; Tubaro, E, 2003)
"We investigated the effect of chronic alcohol ingestion on buccal mucosal ulcer healing by analyzing the interplay between mucosal expression of tumor necrosis factor-alpha (TNF-alpha), endothelin-1 (ET-1), and interleukin-4 (IL-4)."3.70Role of endothelin-1 and interleukin-4 in buccal mucosal ulcer healing: effect of chronic alcohol ingestion. ( Piotrowski, J; Slomiany, A; Slomiany, BL, 1999)
"In our study we have tried to compare the prophylactic effects of superoxide dismutase (SOD), SOD+catalase (CAT), desferrioxamine, verapamil and disulfiram, which are all free oxygen radical (FOR) scavengers, in an animal model of experimental acetic acid colitis."3.69The prophylactic effects of superoxide dismutase, catalase, desferrioxamine, verapamil and disulfiram in experimental colitis. ( Cokneşelí, B; Köksoy, FN; Köse, H; Soybír, GR; Yalçin, O, 1997)
"The effect of subcutaneous and luminal epidermal growth factor (EGF) administration on acetic acid-induced colonic ulceration was determined in adult rats."3.69Effects of epidermal growth factor administration on repair of acetic acid-induced colonic ulcerations in rats. ( Bourne, AJ; Ford, WD; George-Nascimento, C; Howarth, GS; Read, LC; Ribbons, KA, 1997)
"In rat colon damaged by 10% acetic acid and by dinitrochlorobenzene, we test the following hypotheses: (1) mucosal hemodynamic changes are significantly different at the ulcer base, the ulcer margin, and the inflamed non-ulcer-bearing mucosa; and (2) these mucosal hemodynamic changes also vary with time after induction of the colonic injury."3.68Regional differences in mucosal hemodynamics in experimental colonic injury in rats. ( Guth, PH; Leung, FW; Passaro, E; Su, KC; Yonei, Y, 1993)
"The effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on various experimental gastric ulcers and gastric secretion in experimental animals was compared with that of cimetidine and cetraxate."3.67Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals. ( Aratani, S; Enomoto, H; Kimura, K; Mimura, K; Nomura, A; Ueda, F, 1984)
"We studied the healing of acetic acid-induced esophageal ulcers in rats with respect to the cellular kinetics."3.67Healing process of experimental esophageal ulcers induced by acetic acid in rats. ( Fujino, H; Fuse, Y; Kawamoto, K; Kodama, T; Tsuji, H, 1989)
"Oral ulcer is a frequent condition that commonly affects the tongue and in which 75% of the patients experience pain, and 25% report taste changes."1.91Thymus satureioides Coss. combats oral ulcer via inhibition of inflammation, proteolysis, and apoptosis. ( Abdelfattah, MAO; Elbatreek, MH; Fathi, AM; Mahdi, I; Mahmoud, MF; Sobeh, M, 2023)
"major in rats with acetic acid-induced ulcerative colitis (UC)."1.72Evaluation of anti-inflammatory effects of leaf and seed extracts of Plantago major on acetic acid-induced ulcerative colitis in rats. ( Farid, A; Motevalian, M; Noori, M; Sheibani, M; Shojaii, A, 2022)
"Ulcers were induced by serosal application of 80 % acetic acid to the stomach of rats anaesthetized with 50 mg/kg thiopentone sodium and treatment was given three times daily."1.46Effects of quinine on gastric ulcer healing in Wistar rats. ( Adeniyi, OS; Friday, ET; Makinde, OV; Olaleye, SB, 2017)
"Cetraxate was effective in preventing only stress-induced ulcers and had almost no effect on other experimental ulcers."1.27Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals. ( Aratani, S; Enomoto, H; Kimura, K; Mimura, K; Nomura, A; Ueda, F, 1984)
"Cimetidine was effective in preventing stress- and acetic acid-induced ulcers but had no significant effect on Shay, indomethacin-induced and histamine-induced ulcers."1.27Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals. ( Aratani, S; Enomoto, H; Kimura, K; Mimura, K; Nomura, A; Ueda, F, 1984)
"Acute colitis was induced in 6 Sprague-Dawley rats by acetic acid enema, while 6 control animals received saline enemas."1.27Identification of experimentally induced colitis by in vitro nuclear magnetic resonance. ( Jacobs, DO; Rolandelli, RH; Rombeau, JL; Saul, SH; Settle, RG; Singer, RL; Wolf, GL, 1985)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.67)18.7374
1990's5 (20.83)18.2507
2000's6 (25.00)29.6817
2010's4 (16.67)24.3611
2020's5 (20.83)2.80

Authors

AuthorsStudies
Farid, A1
Sheibani, M1
Shojaii, A1
Noori, M1
Motevalian, M1
de Oliveira, BMM1
Serpa, PZ1
da Costa Zanatta, ME1
Aires, BA1
Steffler, AM1
Somensi, LB1
Cury, BJ1
Dos Santos, AC1
Venzon, L1
Boeing, T1
Mota da Silva, L1
Roman Junior, WA1
Hitomi, S1
Nodai, T1
Kokabu, S1
Shikayama, T1
Sago-Ito, M1
Nakatomi, C1
Terawaki, K1
Omiya, Y1
Shinoda, M1
Ono, K1
Ipek, E1
Ekren Aşıcı, GS1
Epikmen, ET1
Abbak, M1
Kurt, BK1
Özsoy, ŞY1
Tunca, R1
Elbatreek, MH1
Fathi, AM1
Mahdi, I1
Abdelfattah, MAO1
Mahmoud, MF1
Sobeh, M1
Adeniyi, OS1
Makinde, OV1
Friday, ET1
Olaleye, SB1
Komaki, Y1
Kanmura, S1
Sasaki, F1
Maeda, H1
Oda, K1
Arima, S1
Tanoue, S1
Nasu, Y1
Hashimoto, S1
Mawatari, S1
Tsubouchi, H1
Ido, A1
Scoparo, CT1
Souza, LM1
Dartora, N1
Sassaki, GL1
Santana-Filho, AP1
Werner, MF1
Borato, DG1
Baggio, CH1
Iacomini, M1
Bastaki, SMA1
Al Ahmed, MM1
Al Zaabi, A1
Amir, N1
Adeghate, E1
Tubaro, E1
Belogi, L1
Mezzadri, CM1
Bettelli, E1
OCHS, IL1
Zhuĭkova, SE1
Badmaeva, KE1
Samonina, GE1
Plesskaia, LG1
Poley, JW1
Steyerberg, EW1
Kuipers, EJ1
Dees, J1
Hartmans, R1
Tilanus, HW1
Siersema, PD1
Khan, MS1
Akhter, M1
Chai, J1
Norng, M1
Tarnawski, AS1
Chow, J1
Ueda, F1
Aratani, S1
Mimura, K1
Kimura, K1
Nomura, A1
Enomoto, H1
Warren, BF1
Leung, FW1
Su, KC1
Yonei, Y1
Passaro, E1
Guth, PH1
Köksoy, FN1
Köse, H1
Soybír, GR1
Yalçin, O1
Cokneşelí, B1
Ribbons, KA1
Howarth, GS1
Ford, WD1
George-Nascimento, C1
Bourne, AJ1
Read, LC1
Slomiany, BL1
Piotrowski, J1
Slomiany, A1
Tozkoparan, B1
Aktay, G1
Yeşilada, E1
Tsuji, H1
Fuse, Y1
Kawamoto, K1
Fujino, H1
Kodama, T1
Rolandelli, RH1
Saul, SH1
Settle, RG1
Jacobs, DO1
Singer, RL1
Wolf, GL1
Rombeau, JL1

Other Studies

24 other studies available for acetic acid and Ulcer

ArticleYear
Evaluation of anti-inflammatory effects of leaf and seed extracts of Plantago major on acetic acid-induced ulcerative colitis in rats.
    Journal of ethnopharmacology, 2022, Nov-15, Volume: 298

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Iran; Plant Extracts; Pl

2022
Gastroprotective and gastric healing effects of the aqueous extract of Casearia sylvestris in rodents: Ultrasound, histological and biochemical analyzes.
    Journal of ethnopharmacology, 2022, Nov-15, Volume: 298

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Casearia; Ethanol; Female; Gastric Mucosa; Mice; Mucins; Ni

2022
Hepcidin expression in the trigeminal ganglion and the oral mucosa in an oral ulcerative mucositis rat model.
    PloS one, 2023, Volume: 18, Issue:4

    Topics: Acetic Acid; Animals; Hepcidins; Iron; Male; Mouth Mucosa; Mucositis; Pain; Quality of Life; Rats; R

2023
Evaluation of Acetic Acid-Induced Chronic Gastric Ulcer Healing by Propionyl-L-Carnitine Administration.
    Chemistry & biodiversity, 2023, Volume: 20, Issue:7

    Topics: Acetic Acid; Animals; Cyclooxygenase 2; Epidermal Growth Factor; Rats; Rats, Wistar; Stomach Ulcer;

2023
Thymus satureioides Coss. combats oral ulcer via inhibition of inflammation, proteolysis, and apoptosis.
    Inflammopharmacology, 2023, Volume: 31, Issue:5

    Topics: Acetic Acid; Animals; Apoptosis; Caspase 3; Cyclooxygenase 2; Humans; Inflammation; Matrix Metallopr

2023
Effects of quinine on gastric ulcer healing in Wistar rats.
    Journal of complementary & integrative medicine, 2017, Jun-29, Volume: 14, Issue:4

    Topics: Acetic Acid; Animals; Cinchona; Gastric Mucosa; Inflammation; Lipid Peroxidation; Male; Mucus; Oxida

2017
Hepatocyte Growth Factor Facilitates Esophageal Mucosal Repair and Inhibits the Submucosal Fibrosis in a Rat Model of Esophageal Ulcer.
    Digestion, 2019, Volume: 99, Issue:3

    Topics: Acetic Acid; Animals; Cell Proliferation; Disease Models, Animal; Epithelial Cells; Esophageal Disea

2019
Chemical characterization of heteropolysaccharides from green and black teas (Camellia sinensis) and their anti-ulcer effect.
    International journal of biological macromolecules, 2016, Volume: 86

    Topics: Acetic Acid; Animals; Camellia sinensis; Ethanol; Female; Gastric Mucosa; Glutathione; Plant Leaves;

2016
Effect of turmeric on colon histology, body weight, ulcer, IL-23, MPO and glutathione in acetic-acid-induced inflammatory bowel disease in rats.
    BMC complementary and alternative medicine, 2016, Feb-23, Volume: 16

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Colitis, Ulcerative; Colo

2016
Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug.
    European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3

    Topics: Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon;

2003
Acetic acid gel for the treatment of indolent skin infections.
    Maryland state medical journal, 1956, Volume: 5, Issue:4

    Topics: Acetates; Acetic Acid; Humans; Skin Diseases, Infectious; Ulcer

1956
[Semax and some glyproline peptides accelerate the healing of acetic ulcers in rats].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2003, Issue:4

    Topics: Acetic Acid; Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Male

2003
Ingestion of acid and alkaline agents: outcome and prognostic value of early upper endoscopy.
    Gastrointestinal endoscopy, 2004, Volume: 60, Issue:3

    Topics: Accidents; Acetic Acid; Acids; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Alk

2004
Synthesis, pharmacological activity and hydrolytic behavior of glyceride prodrugs of ibuprofen.
    European journal of medicinal chemistry, 2005, Volume: 40, Issue:4

    Topics: Acetic Acid; Analgesics; Animals; Glycerides; Hydrogen-Ion Concentration; Hydrolysis; Ibuprofen; Mic

2005
A critical role of serum response factor in myofibroblast differentiation during experimental oesophageal ulcer healing in rats.
    Gut, 2007, Volume: 56, Issue:5

    Topics: Acetic Acid; Animals; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Epith

2007
Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Female; Gastric Acid; Gastric Mucosa;

1984
Another model of acetic acid-induced colitis in the rat.
    Alimentary pharmacology & therapeutics, 1994, Volume: 8, Issue:6

    Topics: Acetates; Acetic Acid; Animals; Burns, Chemical; Colitis; Disease Models, Animal; Rats; Ulcer

1994
Regional differences in mucosal hemodynamics in experimental colonic injury in rats.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:7

    Topics: Acetates; Acetic Acid; Acute Disease; Analysis of Variance; Animals; Colon; Colonic Diseases; Dinitr

1993
The prophylactic effects of superoxide dismutase, catalase, desferrioxamine, verapamil and disulfiram in experimental colitis.
    Journal of the Royal College of Surgeons of Edinburgh, 1997, Volume: 42, Issue:1

    Topics: Acetic Acid; Animals; Calcium Channel Blockers; Catalase; Colitis; Colonic Diseases; Deferoxamine; D

1997
Effects of epidermal growth factor administration on repair of acetic acid-induced colonic ulcerations in rats.
    Growth factors (Chur, Switzerland), 1997, Volume: 14, Issue:2-3

    Topics: Acetic Acid; Animals; Cell Division; Colon; Colonic Diseases; Edema; Epidermal Growth Factor; Epithe

1997
Role of endothelin-1 and interleukin-4 in buccal mucosal ulcer healing: effect of chronic alcohol ingestion.
    Biochemical and biophysical research communications, 1999, Apr-13, Volume: 257, Issue:2

    Topics: Acetic Acid; Animals; Apoptosis; Chronic Disease; Endothelin-1; Ethanol; Gene Expression; Interleuki

1999
Synthesis of some 1,2,4-triazolo[3,2-b]-1,3-thiazine-7-ones with potential analgesic and antiinflammatory activities.
    Farmaco (Societa chimica italiana : 1989), 2002, Volume: 57, Issue:2

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Castor Oil; Diarrhea; Do

2002
Healing process of experimental esophageal ulcers induced by acetic acid in rats.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: Acetates; Acetic Acid; Animals; Epithelium; Esophageal Diseases; Male; Rats; Rats, Inbred Strains; R

1989
Identification of experimentally induced colitis by in vitro nuclear magnetic resonance.
    Physiological chemistry and physics and medical NMR, 1985, Volume: 17, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Body Water; Colitis; Disease Models, Animal; In Vitro Techniques; In

1985