Page last updated: 2024-10-16

acetic acid and Obesity

acetic acid has been researched along with Obesity in 37 studies

Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
" fragilis may accelerate obesity, in part, by suppressing acetic acid levels."8.12Gut microbiota accelerates obesity in peri-/post-menopausal women via Bacteroides fragilis and acetic acid. ( Deng, HW; Greenbaum, J; Li, BY; Lin, X; Liu, HM; Liu, RK; Lv, WQ; Qiu, X; Shen, J; Shen, WD; Xiao, HM; Zhu, XZ, 2022)
"When acetic acid was taken daily by obesity-linked type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats under the fed condition, it protected OLETF rats against obesity."6.53Biological Function of Acetic Acid-Improvement in Obesity and Glucose Tolerance by Acetic Acid in Type 2 Diabetic Rats. ( Yamashita, H, 2016)
"Supplementation with dietary acetic acid is well tolerated, has no adverse side effects, and has clinical potential to reduce plasma TAG and FBG concentrations in individuals with type 2 diabetes, and to reduce TAG levels in people who are overweight or obese."5.12Effect of Dietary Acetic Acid Supplementation on Plasma Glucose, Lipid Profiles, and Body Mass Index in Human Adults: A Systematic Review and Meta-analysis. ( Gill, PA; Kellow, NJ; So, D; Valdes, DS, 2021)
"Acetic acid, propionic acid, butyric acid, and total SCFA were significantly reduced in T2D patients compared to overweight/obese in the unadjusted model."4.12Circulating short-chain fatty acids in type 2 diabetic patients and overweight/obese individuals. ( Annuzzi, G; Bozzetto, L; Corrado, A; Costabile, G; Della Pepa, G; Giacco, R; Luongo, D; Rivellese, AA; Salamone, D; Testa, R; Vitale, M, 2022)
"We investigated the effect of acetic acid (AcOH) on the prevention of obesity in high-fat-fed mice."3.75Acetic acid upregulates the expression of genes for fatty acid oxidation enzymes in liver to suppress body fat accumulation. ( Fushimi, T; Kaga, T; Kishi, M; Kondo, T, 2009)
"Acetic acid is a short-chain fatty acid that has demonstrated biomedical potential as a dietary therapeutic agent for the management of chronic and metabolic illness comorbidities."2.72Effect of Dietary Acetic Acid Supplementation on Plasma Glucose, Lipid Profiles, and Body Mass Index in Human Adults: A Systematic Review and Meta-analysis. ( Gill, PA; Kellow, NJ; So, D; Valdes, DS, 2021)
"Obesity is one of the main risk factors for the development of non-communicable diseases, which are now the leading cause of death worldwide."2.72Gut Hormones in Health and Obesity: The Upcoming Role of Short Chain Fatty Acids. ( AlAmri, S; AlFaiz, A; Alghamdi, S; Alhabeeb, H; AlJohani, N; Alotaibi, K; Alotaibi, N; AlRajhi, S; AlShahrani, D; Alsuhail, A; Kutbi, E, 2021)
"When acetic acid was taken daily by obesity-linked type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats under the fed condition, it protected OLETF rats against obesity."2.53Biological Function of Acetic Acid-Improvement in Obesity and Glucose Tolerance by Acetic Acid in Type 2 Diabetic Rats. ( Yamashita, H, 2016)
" Thus, we tested, in this study, whether a daily dosage of Apple Cider Vinegar (ACV) would affect cardiovascular risk factor associated with obesity in high-fat diet (HFD)-induced hyperlipidemic Wistar rats."1.48Apple Cider Vinegar Attenuates Oxidative Stress and Reduces the Risk of Obesity in High-Fat-Fed Male Wistar Rats. ( Abdallah, A; Fethi, BS; Halima, BH; Houda, BJ; Sarra, K; Sonia, G, 2018)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.70)18.7374
1990's1 (2.70)18.2507
2000's4 (10.81)29.6817
2010's20 (54.05)24.3611
2020's11 (29.73)2.80

Authors

AuthorsStudies
Cao, L1
Wu, Y1
Li, W1
Zhang, Z1
Niu, Y1
Li, C1
Gu, S1
Salamone, D1
Costabile, G1
Corrado, A1
Della Pepa, G1
Vitale, M1
Giacco, R1
Luongo, D1
Testa, R1
Rivellese, AA1
Annuzzi, G1
Bozzetto, L1
Shen, WD1
Lin, X1
Liu, HM1
Li, BY1
Qiu, X1
Lv, WQ1
Zhu, XZ1
Greenbaum, J1
Liu, RK1
Shen, J1
Xiao, HM1
Deng, HW1
Rad, ZA1
Mousavi, SN1
Chiti, H1
Hernández, MAG1
Canfora, EE3
Jocken, JWE3
Blaak, EE4
Hosoda, S1
Kawazoe, Y1
Shiba, T1
Numazawa, S1
Manabe, A1
Khattak, JI1
Zahid, U1
Sun, B1
Vatanen, T1
Jayasinghe, TN1
McKenzie, E1
Murphy, R1
O'Sullivan, JM1
Choi, JH1
Kim, MK1
Yeo, SH1
Kim, S1
Valdes, DS1
So, D1
Gill, PA1
Kellow, NJ1
Alhabeeb, H1
AlFaiz, A1
Kutbi, E1
AlShahrani, D1
Alsuhail, A1
AlRajhi, S1
Alotaibi, N1
Alotaibi, K1
AlAmri, S1
Alghamdi, S1
AlJohani, N1
Liang, D1
Zhang, L1
Chen, H1
Zhang, H1
Hu, H1
Dai, X1
van der Beek, CM2
Hermes, GDA1
Goossens, GH2
Holst, JJ2
van Eijk, HM1
Venema, K1
Smidt, H1
Zoetendal, EG1
Dejong, CHC2
Lenaerts, K2
Tsujino, Y1
Olde Damink, SWM1
Beh, BK1
Mohamad, NE1
Yeap, SK1
Ky, H1
Boo, SY1
Chua, JYH1
Tan, SW1
Ho, WY1
Sharifuddin, SA1
Long, K1
Alitheen, NB1
Halima, BH1
Sonia, G1
Sarra, K1
Houda, BJ1
Fethi, BS1
Abdallah, A1
den Hartigh, LJ1
Gao, Z1
Goodspeed, L1
Wang, S1
Das, AK1
Burant, CF1
Chait, A1
Blaser, MJ1
Iida, T1
Ubukata, M1
Mitani, I1
Nakagawa, Y1
Maeda, K1
Imai, H1
Ogoshi, Y1
Hotta, T1
Sakata, S1
Sano, R1
Morinaga, H1
Negoro, T1
Oshida, S1
Tanaka, M1
Inaba, T1
Palomo-Buitrago, ME1
Sabater-Masdeu, M1
Moreno-Navarrete, JM1
Caballano-Infantes, E1
Arnoriaga-Rodríguez, M1
Coll, C1
Ramió, L1
Palomino-Schätzlein, M1
Gutiérrez-Carcedo, P1
Pérez-Brocal, V1
Simó, R1
Moya, A1
Ricart, W1
Herance, JR1
Fernández-Real, JM1
Kwak, HJ1
Pyun, YM1
Kim, JY1
Pagire, HS1
Kim, KY1
Kim, KR1
Rhee, SD1
Jung, WH1
Song, JS1
Bae, MA1
Lee, DH1
Ahn, JH1
Lee, JH2
Cho, HD1
Jeong, JH1
Lee, MK2
Jeong, YK2
Shim, KH1
Seo, KI2
Darzi, J1
Frost, GS1
Montaser, R1
Yap, J1
Robertson, MD1
Ok, E1
Do, GM1
Lim, Y1
Park, JE1
Park, YJ1
Kwon, O1
Labbé, SM1
Noll, C1
Grenier-Larouche, T1
Kunach, M1
Bouffard, L1
Phoenix, S1
Guérin, B1
Baillargeon, JP1
Langlois, MF1
Turcotte, EE1
Carpentier, AC1
Lee, J1
Choi, RY1
Lee, HI1
Kim, MJ1
Petsiou, EI1
Mitrou, PI1
Raptis, SA1
Dimitriadis, GD1
Yamashita, H1
Bouderbala, H1
Kaddouri, H1
Kheroua, O1
Saidi, D1
Kondo, T2
Kishi, M2
Fushimi, T2
Kaga, T2
Ugajin, S1
Nakamura, N1
Lin, HC1
McSweeney, CS1
Mackie, RI1
Gaskins, HR1
Okazaki, Y1
Sitanggang, NV1
Sato, S1
Ohnishi, N1
Inoue, J1
Iguchi, T1
Watanabe, T1
Tomotake, H1
Harada, K1
Kato, N1
Varvarelis, N1
Khallafi, H1
Pappachen, B1
Krishnamurthy, M1
Seufert, CD1
Mewes, W1
Soeling, HD1
Japour, CJ1
Vohra, R1
Vohra, PK1
Garfunkel, L1
Chin, N1
Schrauwen, P1
Van Aggel-Leijssen, DP1
Borghouts, LB1
Wagenmakers, AJ1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Galactooligosaccharide (GOS) on Peripheral Insulin Sensitivity and Body Weight Control in Obese Adults With Impaired Glucose Homeostasis[NCT02271776]46 participants (Actual)Interventional2014-10-31Completed
Using a Complex Carbohydrate Mixture Added to a High-protein Diet to Steer Fermentation and Improve Metabolic, Gut and Brain Health[NCT05354245]44 participants (Anticipated)Interventional2022-09-08Recruiting
Apple Cider Vinegar for the Prevention of Urinary Lithiasis (APUL)[NCT04073719]50 participants (Anticipated)Interventional2019-09-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for acetic acid and Obesity

ArticleYear
The Short-Chain Fatty Acid Acetate in Body Weight Control and Insulin Sensitivity.
    Nutrients, 2019, Aug-18, Volume: 11, Issue:8

    Topics: Acetic Acid; Animals; Appetite; Blood Glucose; Body Weight; Colon; Cytokines; Dietary Fiber; Energy

2019
Effect of Dietary Acetic Acid Supplementation on Plasma Glucose, Lipid Profiles, and Body Mass Index in Human Adults: A Systematic Review and Meta-analysis.
    Journal of the Academy of Nutrition and Dietetics, 2021, Volume: 121, Issue:5

    Topics: Acetic Acid; Adult; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Dietary Supplements;

2021
Gut Hormones in Health and Obesity: The Upcoming Role of Short Chain Fatty Acids.
    Nutrients, 2021, Jan-31, Volume: 13, Issue:2

    Topics: Acetic Acid; Animals; Appetite; Appetite Regulation; Butyrates; Central Nervous System; Cholecystoki

2021
Effect and mechanisms of action of vinegar on glucose metabolism, lipid profile, and body weight.
    Nutrition reviews, 2014, Volume: 72, Issue:10

    Topics: Acetic Acid; Animals; Controlled Clinical Trials as Topic; Diabetes Mellitus; Glucose; Humans; Insul

2014
Biological Function of Acetic Acid-Improvement in Obesity and Glucose Tolerance by Acetic Acid in Type 2 Diabetic Rats.
    Critical reviews in food science and nutrition, 2016, Jul-29, Volume: 56 Suppl 1

    Topics: Acetate-CoA Ligase; Acetic Acid; Adipose Tissue; Animals; Diabetes Mellitus, Experimental; Diabetes

2016
Mechanisms of microbial hydrogen disposal in the human colon and implications for health and disease.
    Annual review of food science and technology, 2010, Volume: 1

    Topics: Acetic Acid; Colon; Colorectal Neoplasms; Humans; Hydrogen; Inflammatory Bowel Diseases; Methane; Me

2010

Trials

5 trials available for acetic acid and Obesity

ArticleYear
Supplementation of Diet With Galacto-oligosaccharides Increases Bifidobacteria, but Not Insulin Sensitivity, in Obese Prediabetic Individuals.
    Gastroenterology, 2017, Volume: 153, Issue:1

    Topics: Acetic Acid; Acute-Phase Proteins; Adiposity; Aged; Bifidobacterium; Blood Glucose; Body Mass Index;

2017
Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial.
    Scientific reports, 2017, 05-24, Volume: 7, Issue:1

    Topics: Acetic Acid; Adult; Butyric Acid; Colon; Cross-Over Studies; Double-Blind Method; Energy Metabolism;

2017
Influence of the tolerability of vinegar as an oral source of short-chain fatty acids on appetite control and food intake.
    International journal of obesity (2005), 2014, Volume: 38, Issue:5

    Topics: Acetic Acid; Adult; Appetite Regulation; Cross-Over Studies; Eating; Energy Intake; Fatty Acids, Vol

2014
Improved cardiac function and dietary fatty acid metabolism after modest weight loss in subjects with impaired glucose tolerance.
    American journal of physiology. Endocrinology and metabolism, 2014, Jun-15, Volume: 306, Issue:12

    Topics: Acetic Acid; Body Mass Index; Carbon Radioisotopes; Combined Modality Therapy; Diet, Reducing; Dieta

2014
Vinegar intake reduces body weight, body fat mass, and serum triglyceride levels in obese Japanese subjects.
    Bioscience, biotechnology, and biochemistry, 2009, Volume: 73, Issue:8

    Topics: Abdominal Fat; Acetic Acid; Adipose Tissue; Adult; Asian People; Blood Pressure; Body Weight; Double

2009

Other Studies

26 other studies available for acetic acid and Obesity

ArticleYear
Cornus officinalis vinegar reduces body weight and attenuates hepatic steatosis in mouse model of nonalcoholic fatty liver disease.
    Journal of food science, 2022, Volume: 87, Issue:7

    Topics: Acetic Acid; Animals; Cholesterol; Cornus; Diet, High-Fat; Disease Models, Animal; Female; Liver; Mi

2022
Circulating short-chain fatty acids in type 2 diabetic patients and overweight/obese individuals.
    Acta diabetologica, 2022, Volume: 59, Issue:12

    Topics: Acetic Acid; Butyric Acid; Diabetes Mellitus, Type 2; Fatty Acids, Volatile; Humans; Obesity; Overwe

2022
Gut microbiota accelerates obesity in peri-/post-menopausal women via Bacteroides fragilis and acetic acid.
    International journal of obesity (2005), 2022, Volume: 46, Issue:10

    Topics: Acetic Acid; Bacteroides fragilis; Female; Gastrointestinal Microbiome; Humans; Obesity; Postmenopau

2022
A low-carb diet increases fecal short-chain fatty acids in feces of obese women following a weight-loss program: randomized feeding trial.
    Scientific reports, 2023, 10-24, Volume: 13, Issue:1

    Topics: Acetic Acid; Butyric Acid; Diet; Fatty Acids, Volatile; Feces; Female; Humans; Insulins; Interleukin

2023
Anti-Obesity Effect of Ginkgo Vinegar, a Fermented Product of Ginkgo Seed Coat, in Mice Fed a High-Fat Diet and 3T3-L1 Preadipocyte Cells.
    Nutrients, 2020, Jan-16, Volume: 12, Issue:1

    Topics: 3T3 Cells; Acetic Acid; Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; CCAAT-Enhancer-Bindi

2020
Hidradenitis suppurativa, a rare skin disease.
    JPMA. The Journal of the Pakistan Medical Association, 2020, Volume: 70, Issue:2

    Topics: Acetic Acid; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Anti-Infective Agents, Local; An

2020
Desacetyl-α-MSH and α-MSH have sex specific interactions with diet to influence mouse gut morphology, metabolites and microbiota.
    Scientific reports, 2020, 11-03, Volume: 10, Issue:1

    Topics: Acetic Acid; alpha-MSH; Animals; Diet, High-Fat; Female; Gastrointestinal Microbiome; Genotype; Male

2020
Short-term Cudrania tricuspidata fruit vinegar administration attenuates obesity in high-fat diet-fed mice by improving fat accumulation and metabolic parameters.
    Scientific reports, 2020, 12-03, Volume: 10, Issue:1

    Topics: Acetic Acid; Animals; Biomarkers; Cell Line; Cell Survival; Diet, High-Fat; Disease Models, Animal;

2020
Potato resistant starch inhibits diet-induced obesity by modifying the composition of intestinal microbiota and their metabolites in obese mice.
    International journal of biological macromolecules, 2021, Jun-01, Volume: 180

    Topics: Acetic Acid; Animals; Bacteroides; Bifidobacterium; Body Weight; Diet, High-Fat; Gastrointestinal Mi

2021
A New Agonist for Peroxisome Proliferation-activated Receptor γ (PPARγ), Fraglide-1 from Zhenjiang Fragrant Vinegar: Screening and Characterization Based on Cell Culture Experiments.
    Journal of oleo science, 2017, Jun-01, Volume: 66, Issue:6

    Topics: 4-Butyrolactone; Acetic Acid; Animals; Anti-Obesity Agents; Cells, Cultured; Chlorocebus aethiops; C

2017
Anti-obesity and anti-inflammatory effects of synthetic acetic acid vinegar and Nipa vinegar on high-fat-diet-induced obese mice.
    Scientific reports, 2017, 07-27, Volume: 7, Issue:1

    Topics: Acetic Acid; Adipokines; Animals; Anti-Inflammatory Agents; Anti-Obesity Agents; Cholesterol; Diet,

2017
Apple Cider Vinegar Attenuates Oxidative Stress and Reduces the Risk of Obesity in High-Fat-Fed Male Wistar Rats.
    Journal of medicinal food, 2018, Volume: 21, Issue:1

    Topics: Acetic Acid; Animals; Antioxidants; Diet, High-Fat; Fruit and Vegetable Juices; Glutathione Peroxida

2018
Obese Mice Losing Weight Due to trans-10,cis-12 Conjugated Linoleic Acid Supplementation or Food Restriction Harbor Distinct Gut Microbiota.
    The Journal of nutrition, 2018, 04-01, Volume: 148, Issue:4

    Topics: Acetic Acid; Animals; Bacteria; Butyric Acid; Caloric Restriction; Colon; Diet, High-Fat; Diet, Redu

2018
Discovery of potent liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitors, thiazole-4-acetic acid derivatives, for the treatment of diabetes, hepatic steatosis, and obesity.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Acetic Acid; Animals; Diabetes Mellitus; Drug Discovery; Enzyme Inhibitors; Fatty Liver; Liver; Male

2018
Glutamate interactions with obesity, insulin resistance, cognition and gut microbiota composition.
    Acta diabetologica, 2019, Volume: 56, Issue:5

    Topics: Acetic Acid; Bacteria; Cognition; Feces; Female; Gastrointestinal Microbiome; Glutamic Acid; Glutami

2019
Synthesis and biological evaluation of aminobenzimidazole derivatives with a phenylcyclohexyl acetic acid group as anti-obesity and anti-diabetic agents.
    Bioorganic & medicinal chemistry letters, 2013, Aug-15, Volume: 23, Issue:16

    Topics: Acetic Acid; Animals; Anti-Obesity Agents; Benzimidazoles; Cells, Cultured; Cyclization; Diabetes Me

2013
New vinegar produced by tomato suppresses adipocyte differentiation and fat accumulation in 3T3-L1 cells and obese rat model.
    Food chemistry, 2013, Dec-01, Volume: 141, Issue:3

    Topics: 3T3-L1 Cells; Acetic Acid; Adipocytes; Animals; Anti-Obesity Agents; Body Weight; Cell Differentiati

2013
Pomegranate vinegar attenuates adiposity in obese rats through coordinated control of AMPK signaling in the liver and adipose tissue.
    Lipids in health and disease, 2013, Nov-02, Volume: 12

    Topics: Acetic Acid; Adipose Tissue; Adiposity; AMP-Activated Protein Kinases; Animals; Carnitine O-Palmitoy

2013
Anti-obesity and anti-insulin resistance effects of tomato vinegar beverage in diet-induced obese mice.
    Food & function, 2014, Jul-25, Volume: 5, Issue:7

    Topics: Acetic Acid; Acetyl-CoA Carboxylase; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Beverag

2014
[Anti-obesogenic effect of apple cider vinegar in rats subjected to a high fat diet].
    Annales de cardiologie et d'angeiologie, 2016, Volume: 65, Issue:3

    Topics: Acetic Acid; Animals; Antioxidants; Body Weight; Diet, High-Fat; Disease Models, Animal; Male; Malus

2016
Acetic acid upregulates the expression of genes for fatty acid oxidation enzymes in liver to suppress body fat accumulation.
    Journal of agricultural and food chemistry, 2009, Jul-08, Volume: 57, Issue:13

    Topics: Acetic Acid; Acetyl-CoA Carboxylase; Animals; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Fa

2009
Burdock fermented by Aspergillus awamori elevates cecal Bifidobacterium, and reduces fecal deoxycholic acid and adipose tissue weight in rats fed a high-fat diet.
    Bioscience, biotechnology, and biochemistry, 2013, Volume: 77, Issue:1

    Topics: Acetic Acid; Adipose Tissue; Animals; Arctium; Aspergillus; Bifidobacterium; Butyric Acid; Cecum; De

2013
Natural therapies--when ignorance is not bliss!!
    Journal of the American Geriatrics Society, 2007, Volume: 55, Issue:11

    Topics: Acetic Acid; Acute Disease; Aged; Drug Interactions; Hiccup; Homeopathy; Humans; Hypercholesterolemi

2007
Effect of long-term starvation on acetate and ketone body metabolism in obese patients.
    European journal of clinical investigation, 1984, Volume: 14, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetates; Acetic Acid; Acetoacetates; Fatty Acids, Nonesterified; Humans; Hyd

1984
Management of heel pain syndrome with acetic acid iontophoresis.
    Journal of the American Podiatric Medical Association, 1999, Volume: 89, Issue:5

    Topics: Acetic Acid; Adult; Aged; Chronic Disease; Exostoses; Fasciitis; Female; Follow-Up Studies; Heel; Hu

1999
Determinants of the acetate recovery factor: implications for estimation of [13C]substrate oxidation.
    Clinical science (London, England : 1979), 2000, Volume: 98, Issue:5

    Topics: Acetic Acid; Adult; Aging; Body Composition; Carbon Isotopes; Diabetes Mellitus, Type 2; Energy Meta

2000