Page last updated: 2024-10-16

acetic acid and Nociceptive Pain

acetic acid has been researched along with Nociceptive Pain in 27 studies

Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.

Nociceptive Pain: Dull or sharp aching pain caused by stimulated NOCICEPTORS due to tissue injury, inflammation or diseases. It can be divided into somatic or tissue pain and VISCERAL PAIN.

Research Excerpts

ExcerptRelevanceReference
" Methods The anti-nociceptive potentials of the extracts were studied using the acetic acid-induced writhing test in mice and the antipyretic activity was investigated using yeast-induced pyrexia in rats."3.85In vivo analgesic, antipyretic and anti-inflammatory potential of leaf extracts and fractions of Eria javanica. ( Ahmed, F; Bhuiya, NM; Hasan, M; Kabir, MS; Mahmud, ZA; Qais, N; Uddin, MM, 2017)
" Xylene-induced ear edema, carrageenan-induced paw edema and acetic acid-induced vascular permeability test were used to investigate the anti-inflammatory activities of GL in mice."3.81Observing Anti-inflammatory and Anti-nociceptive Activities of Glycyrrhizin Through Regulating COX-2 and Pro-inflammatory Cytokines Expressions in Mice. ( Li, YX; Ma, L; Niu, Y; Niu, YT; Shi, GJ; Sun, T; Wang, HL; Wu, J; Yu, JQ; Zheng, J, 2015)
" Rhodojaponin III (RJ-III) has been identified as the main pharmacological activity and toxic component of the herb; however, oral antinociception and mechanism of RJ-III have not yet been investigated."1.72Evaluation of Rhodojaponin III from Rhododendron molle G. Don on oral antinociceptive activity, mechanism of action, and subacute toxicity in rodents. ( Feng, Y; Liu, M; Sun, S; Wang, Y; Yang, J; Yang, Q; Zhang, J; Zhao, J, 2022)
"375 mg/kg and above may cause side effect after long-term oral administration."1.72Evaluation of Rhodojaponin III from Rhododendron molle G. Don on oral antinociceptive activity, mechanism of action, and subacute toxicity in rodents. ( Feng, Y; Liu, M; Sun, S; Wang, Y; Yang, J; Yang, Q; Zhang, J; Zhao, J, 2022)
"Chronic neuropathic pain is a burden to millions of patients every day."1.51Neuropathic insult increases the responsiveness to acetic acid in mice. ( Bagdas, D; Damaj, MI; Gurdap, CO; Markwalter, PS; Neddenriep, B, 2019)
"Neuropathic pain was induced by chronic constriction injury (CCI) of the sciatic nerve of C57BL/6J male mice and examined in assays of acetic acid (AA)-induced stretching or conditioned place aversion to assess nociceptive and aversive behaviors."1.51Neuropathic insult increases the responsiveness to acetic acid in mice. ( Bagdas, D; Damaj, MI; Gurdap, CO; Markwalter, PS; Neddenriep, B, 2019)
"Most drugs used to treat pain and inflammation have potential side effects, which makes it necessary to search for new sources of bioactive molecules."1.48LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice. ( Alencar Filho, EB; Almeida, JRGDS; Barreiro, EJL; Diniz, TC; Lavor, ÉM; Lima, LM; Lima-Saraiva, SRG; Mendes, RL; Oliveira Júnior, RG; Silva, JC; Silva, MGE; Soares, JMD, 2018)
"Pain and inflammation are complex clinical conditions that are present in a wide variety of disorders."1.48LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice. ( Alencar Filho, EB; Almeida, JRGDS; Barreiro, EJL; Diniz, TC; Lavor, ÉM; Lima, LM; Lima-Saraiva, SRG; Mendes, RL; Oliveira Júnior, RG; Silva, JC; Silva, MGE; Soares, JMD, 2018)
"Acetic acid (AA; 0."1.40Role of spinal GABAA receptors in pudendal inhibition of nociceptive and nonnociceptive bladder reflexes in cats. ( de Groat, WC; Reese, J; Roppolo, JR; Schwen, Z; Shen, B; Tai, C; Wang, J; Xiao, Z, 2014)
"Pre-treatment with yohimbine, an alpha 2-adrenergic receptor antagonist, notably reversed the antinociceptive activity induced by octacosanol in the abdominal constriction test."1.38Antinociceptive and anti-inflammatory effects of octacosanol from the leaves of Sabicea grisea var. grisea in mice. ( Barreto, E; Brito, FA; Conserva, LM; De Souza Ferro, JN; Lemos, RPL; Oliveira, AM, 2012)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's26 (96.30)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Yang, J1
Yang, Q1
Zhao, J1
Sun, S1
Liu, M1
Wang, Y1
Feng, Y1
Zhang, J1
Wang, D1
Yang, H1
Liang, Y1
Wang, X1
Du, X1
Li, R1
Jiang, Y1
Ye, J1
Boakye-Gyasi, E1
Henneh, IT1
Abotsi, WKM1
Ameyaw, EO1
Woode, E1
Spencer, NJ1
Magnúsdóttir, EI1
Jakobsson, JET1
Kestell, G1
Chen, BN1
Morris, D1
Brookes, SJ1
Lagerström, MC1
Palit, P2
Mukherjee, D1
Mahanta, P1
Shadab, M1
Ali, N2
Roychoudhury, S1
Asad, M1
Mandal, SC2
Shoaib, M1
Shah, SWA1
Shah, I1
Shafiullah, -1
Ayaz, M1
Tahir, MN1
Akhtar, S1
Ayub, MT1
Chen, Y1
Yu, H1
Guo, F1
Wu, Y1
Li, Y1
Hishe, HZ1
Ambech, TA1
Hiben, MG1
Fanta, BS1
Silva, JC1
Oliveira Júnior, RG1
Silva, MGE1
Lavor, ÉM1
Soares, JMD1
Lima-Saraiva, SRG1
Diniz, TC1
Mendes, RL1
Alencar Filho, EB1
Barreiro, EJL1
Lima, LM1
Almeida, JRGDS1
Gurdap, CO1
Markwalter, PS1
Neddenriep, B1
Bagdas, D1
Damaj, MI1
Rios, ER1
Rocha, NF1
Carvalho, AM1
Vasconcelos, LF1
Dias, ML1
de Sousa, DP2
de Sousa, FC1
Fonteles, MM1
Magro, DA1
Hohmann, MS1
Mizokami, SS2
Cunha, TM2
Alves-Filho, JC1
Casagrande, R2
Ferreira, SH2
Liew, FY1
Cunha, FQ2
Verri, WA2
Ren, W1
Yuan, L1
Li, J1
Huang, XJ1
Chen, S1
Zou, DJ1
Liu, X1
Yang, XZ1
Xiao, Z1
Reese, J1
Schwen, Z1
Shen, B1
Wang, J1
Roppolo, JR1
de Groat, WC1
Tai, C1
Qiu, F1
Qiu, CY1
Cai, H1
Liu, TT1
Qu, ZW1
Yang, Z1
Li, JD1
Zhou, QY1
Hu, WP1
Wang, HL1
Li, YX1
Niu, YT1
Zheng, J1
Wu, J1
Shi, GJ1
Ma, L1
Niu, Y1
Sun, T1
Yu, JQ1
Ganguly, A1
Al Mahmud, Z1
Kumar Saha, S1
Abdur Rahman, SM1
da Silva Brum, E1
da Rosa Moreira, L1
da Silva, ARH1
Boligon, AA1
Carvalho, FB1
Athayde, ML1
Brandão, R1
Oliveira, SM1
Azevedo, LF1
Silva, SMD1
Navarro, LB1
Yamaguchi, LF1
Nascimento, CGO1
Soncini, R1
Ishikawa, T1
Souto-Maior, FN1
Fonsêca, DV1
Salgado, PR1
Monte, LO1
de Almeida, RN1
Barkatullah, -1
Ibrar, M1
Ikram, N1
Rauf, A1
Hadda, TB1
Bawazeer, S1
Khan, H1
Pervez, S1
Bhunia, B1
Bhuiya, NM1
Hasan, M1
Mahmud, ZA1
Qais, N1
Kabir, MS1
Ahmed, F1
Uddin, MM1
Pavao-de-Souza, GF1
Zarpelon, AC1
Tedeschi, GC1
Sanson, JS1
Ohsawa, M1
Mutoh, J1
Asato, M1
Yamamoto, S1
Ono, H1
Hisa, H1
Kamei, J1
Oliveira, AM1
Conserva, LM1
De Souza Ferro, JN1
Brito, FA1
Lemos, RPL1
Barreto, E1
Montrucchio, DP1
Miguel, OG1
Zanin, SM1
da Silva, GA1
Cardozo, AM1
Santos, AR1

Other Studies

27 other studies available for acetic acid and Nociceptive Pain

ArticleYear
Evaluation of Rhodojaponin III from Rhododendron molle G. Don on oral antinociceptive activity, mechanism of action, and subacute toxicity in rodents.
    Journal of ethnopharmacology, 2022, Aug-10, Volume: 294

    Topics: Acetic Acid; Analgesics; Animals; Diterpenes; Molecular Docking Simulation; Neuralgia; Nociceptive P

2022
Antinociceptive Effect of Spirocyclopiperazinium Salt Compound DXL-A-24 and the Underlying Mechanism.
    Neurochemical research, 2019, Volume: 44, Issue:12

    Topics: Acetic Acid; Analgesics; Animals; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Prot

2019
Hydro-ethanolic leaf extract of Ziziphus abyssinica Hochst Ex A. Rich (Rhamnaceae) exhibits anti-nociceptive effects in murine models.
    BMC complementary and alternative medicine, 2017, Apr-26, Volume: 17, Issue:1

    Topics: Acetic Acid; Africa; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; D

2017
CGRPα within the Trpv1-Cre population contributes to visceral nociception.
    American journal of physiology. Gastrointestinal and liver physiology, 2018, 02-01, Volume: 314, Issue:2

    Topics: Acetic Acid; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Disease Models, Animal; Gan

2018
Attenuation of nociceptive pain and inflammatory disorders by total steroid and terpenoid fraction of Euphorbia tirucalli Linn root in experimental in vitro and in vivo model.
    Inflammopharmacology, 2018, Volume: 26, Issue:1

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Cell Line, Tumor; Cytokines;

2018
Synthesis, antinociceptive activity and structure activity relationship of flavone derivatives.
    Pakistan journal of pharmaceutical sciences, 2017, Volume: 30, Issue:5

    Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Flavones; Formaldehyde;

2017
Antinociceptive and anti-inflammatory activities of a standardizedextract of bis-iridoids from Pterocephalus hookeri.
    Journal of ethnopharmacology, 2018, Apr-24, Volume: 216

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Caprifoliaceae; Carrageenan; Dexamethaso

2018
Anti-nociceptive effect of methanol extract of leaves of Senna singueana in mice.
    Journal of ethnopharmacology, 2018, May-10, Volume: 217

    Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationsh

2018
LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice.
    PloS one, 2018, Volume: 13, Issue:7

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrage

2018
Neuropathic insult increases the responsiveness to acetic acid in mice.
    Behavioural pharmacology, 2019, Volume: 30, Issue:6

    Topics: Acetic Acid; Animals; Conditioning, Classical; Disease Models, Animal; Hyperalgesia; Male; Mice; Mic

2019
TRP and ASIC channels mediate the antinociceptive effect of citronellyl acetate.
    Chemico-biological interactions, 2013, May-25, Volume: 203, Issue:3

    Topics: Acetic Acid; Acid Sensing Ion Channels; Acute Pain; Administration, Oral; Analgesics; Animals; Disea

2013
An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2013, Volume: 46, Issue:7

    Topics: Acetic Acid; Animals; Benzoquinones; Homozygote; Hot Temperature; Hyperalgesia; Interleukin-1 Recept

2013
Ethanolic extract of Aconiti Brachypodi Radix attenuates nociceptive pain probably via inhibition of voltage-dependent Na⁺ channel.
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2012, Volume: 9, Issue:4

    Topics: Acetic Acid; Aconitum; Analgesics; Animals; Dinoprostone; Disease Models, Animal; Dose-Response Rela

2012
Role of spinal GABAA receptors in pudendal inhibition of nociceptive and nonnociceptive bladder reflexes in cats.
    American journal of physiology. Renal physiology, 2014, Apr-01, Volume: 306, Issue:7

    Topics: Acetic Acid; Animals; Cats; Disease Models, Animal; Electric Stimulation; Female; GABA Antagonists;

2014
Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin, V1A receptor in primary sensory neurons.
    British journal of pharmacology, 2014, Volume: 171, Issue:12

    Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Action Potentials; Analge

2014
Observing Anti-inflammatory and Anti-nociceptive Activities of Glycyrrhizin Through Regulating COX-2 and Pro-inflammatory Cytokines Expressions in Mice.
    Inflammation, 2015, Volume: 38, Issue:6

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Cyc

2015
Evaluation of antinociceptive and antidiarrhoeal properties of Manilkara zapota leaves in Swiss albino mice.
    Pharmaceutical biology, 2016, Volume: 54, Issue:8

    Topics: Acetic Acid; Analgesics; Animals; Antidiarrheals; Behavior, Animal; Castor Oil; Diarrhea; Disease Mo

2016
Tabernaemontana catharinensis ethyl acetate fraction presents antinociceptive activity without causing toxicological effects in mice.
    Journal of ethnopharmacology, 2016, Sep-15, Volume: 191

    Topics: Acetates; Acetic Acid; Administration, Oral; Analgesics; Animals; Apocynaceae; Behavior, Animal; Cap

2016
Evidence of anti-inflammatory and antinociceptive activities of Plinia edulis leaf infusion.
    Journal of ethnopharmacology, 2016, Nov-04, Volume: 192

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Chemotaxi

2016
Antinociceptive and anticonvulsant effects of the monoterpene linalool oxide.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Acetic Acid; Acyclic Monoterpenes; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Cyclohexa

2017
In vivo antinociceptive and muscle relaxant activity of leaf and bark of Buddleja asiatica L.
    Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:5

    Topics: Acetic Acid; Analgesics; Animals; Buddleja; Disease Models, Animal; Dose-Response Relationship, Drug

2016
Total steroid and terpenoid enriched fraction from Euphorbia neriifolia Linn offers protection against nociceptive-pain, inflammation, and in vitro arthritis model: An insight of mechanistic study.
    International immunopharmacology, 2016, Volume: 41

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonate 12-Lipoxygenase; Arthritis;

2016
In vivo analgesic, antipyretic and anti-inflammatory potential of leaf extracts and fractions of Eria javanica.
    Journal of complementary & integrative medicine, 2017, Mar-01, Volume: 14, Issue:1

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Carrageenan; Edema; Female

2017
Acetic acid- and phenyl-p-benzoquinone-induced overt pain-like behavior depends on spinal activation of MAP kinases, PI(3)K and microglia in mice.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:3

    Topics: Acetic Acid; Androstadienes; Animals; Anthracenes; Benzoquinones; Disease Models, Animal; Flavonoids

2012
Carnosine has antinociceptive properties in the inflammation-induced nociceptive response in mice.
    European journal of pharmacology, 2012, May-05, Volume: 682, Issue:1-3

    Topics: Acetic Acid; Analgesics; Animals; Carnosine; Formaldehyde; Gene Expression Regulation; Inflammation;

2012
Antinociceptive and anti-inflammatory effects of octacosanol from the leaves of Sabicea grisea var. grisea in mice.
    International journal of molecular sciences, 2012, Volume: 13, Issue:2

    Topics: Acetic Acid; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Anti-Inflammatory Agents;

2012
Antinociceptive effects of a chloroform extract and the alkaloid dicentrine isolated from fruits of Ocotea puberula.
    Planta medica, 2012, Volume: 78, Issue:14

    Topics: Acetic Acid; Alkaloids; Analgesics, Opioid; Animals; Aporphines; Chloroform; Dose-Response Relations

2012