Page last updated: 2024-10-16

acetic acid and Neuralgia

acetic acid has been researched along with Neuralgia in 16 studies

Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
"Pentoxifylline (PTX) has strong antyinflamatory effects, decreases TNF-alpha and other proinflammatory cytokines production."5.38Pentoxifylline modifies central and peripheral vagal mechanism in acute and chronic pain models. ( Dobrogowski, J; Nowak, Ł; Thor, PJ; Wordliczek, J; Zurowski, D, 2012)
" Rhodojaponin III (RJ-III) has been identified as the main pharmacological activity and toxic component of the herb; however, oral antinociception and mechanism of RJ-III have not yet been investigated."1.72Evaluation of Rhodojaponin III from Rhododendron molle G. Don on oral antinociceptive activity, mechanism of action, and subacute toxicity in rodents. ( Feng, Y; Liu, M; Sun, S; Wang, Y; Yang, J; Yang, Q; Zhang, J; Zhao, J, 2022)
"375 mg/kg and above may cause side effect after long-term oral administration."1.72Evaluation of Rhodojaponin III from Rhododendron molle G. Don on oral antinociceptive activity, mechanism of action, and subacute toxicity in rodents. ( Feng, Y; Liu, M; Sun, S; Wang, Y; Yang, J; Yang, Q; Zhang, J; Zhao, J, 2022)
"Chronic neuropathic pain is a burden to millions of patients every day."1.51Neuropathic insult increases the responsiveness to acetic acid in mice. ( Bagdas, D; Damaj, MI; Gurdap, CO; Markwalter, PS; Neddenriep, B, 2019)
"Neuropathic pain was induced by chronic constriction injury (CCI) of the sciatic nerve of C57BL/6J male mice and examined in assays of acetic acid (AA)-induced stretching or conditioned place aversion to assess nociceptive and aversive behaviors."1.51Neuropathic insult increases the responsiveness to acetic acid in mice. ( Bagdas, D; Damaj, MI; Gurdap, CO; Markwalter, PS; Neddenriep, B, 2019)
"Rotarod and catalepsy tests were used to identify potential side effects, while the functional effect of TRR469 was studied using [(3)H]-d-aspartate release from synaptosomes."1.40TRR469, a potent A(1) adenosine receptor allosteric modulator, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice. ( Baraldi, PG; Borea, PA; Gessi, S; Merighi, S; Romagnoli, R; Targa, M; Varani, K; Vincenzi, F, 2014)
"TRR469 was anti-allodynic in the neuropathic pain model and did not display locomotor or cataleptic side effects."1.40TRR469, a potent A(1) adenosine receptor allosteric modulator, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice. ( Baraldi, PG; Borea, PA; Gessi, S; Merighi, S; Romagnoli, R; Targa, M; Varani, K; Vincenzi, F, 2014)
"Pentoxifylline (PTX) has strong antyinflamatory effects, decreases TNF-alpha and other proinflammatory cytokines production."1.38Pentoxifylline modifies central and peripheral vagal mechanism in acute and chronic pain models. ( Dobrogowski, J; Nowak, Ł; Thor, PJ; Wordliczek, J; Zurowski, D, 2012)
"Pre-treatment with yohimbine, an alpha 2-adrenergic receptor antagonist, notably reversed the antinociceptive activity induced by octacosanol in the abdominal constriction test."1.38Antinociceptive and anti-inflammatory effects of octacosanol from the leaves of Sabicea grisea var. grisea in mice. ( Barreto, E; Brito, FA; Conserva, LM; De Souza Ferro, JN; Lemos, RPL; Oliveira, AM, 2012)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's10 (62.50)24.3611
2020's3 (18.75)2.80

Authors

AuthorsStudies
Xiong, J1
Zhuang, T1
Ma, Y1
Xu, J1
Ye, J2
Ma, R1
Zhang, S1
Liu, X1
Liu, BF1
Hao, C1
Zhang, G1
Chen, Y1
Yang, J2
Yang, Q1
Zhao, J1
Sun, S1
Liu, M2
Wang, Y1
Feng, Y1
Zhang, J1
Oggianu, L1
Garrone, B1
Fiorentini, F1
Del Bene, F1
Rosignoli, MT1
Di Giorgio, FP1
Kaminski, RM1
Wang, D1
Yang, H1
Liang, Y1
Wang, X1
Du, X1
Li, R1
Jiang, Y1
Gurdap, CO1
Markwalter, PS1
Neddenriep, B1
Bagdas, D1
Damaj, MI1
Nowak, Ł1
Zurowski, D1
Dobrogowski, J1
Wordliczek, J1
Thor, PJ1
Liu, Y2
Wu, Z1
Tang, D2
Xun, X2
Liu, L1
Li, X1
Nie, D1
Xiang, Y1
Yi, J3
Vincenzi, F1
Targa, M1
Romagnoli, R1
Merighi, S1
Gessi, S1
Baraldi, PG1
Borea, PA1
Varani, K1
Tang, J1
Zhang, Y1
Peng, D1
Liu, Z2
Shi, X1
Yang, L1
Li, L1
Chen, L1
Li, Y2
Chen, H1
Ji, G1
Lin, D1
Qiu, Y1
Rapacz, A1
Obniska, J1
Wiklik-Poudel, B1
Rybka, S1
Sałat, K1
Filipek, B1
Nikai, T1
Basbaum, AI1
Ahn, AH1
Shen, J1
Liu, H1
Xu, Y1
Su, YP1
Yu, CX1
Oliveira, AM1
Conserva, LM1
De Souza Ferro, JN1
Brito, FA1
Lemos, RPL1
Barreto, E1
Rácz, I1
Schütz, B1
Abo-Salem, OM1
Zimmer, A1
Daud, A1
Habib, N1
Riera, AS1

Other Studies

16 other studies available for acetic acid and Neuralgia

ArticleYear
Optimization of bifunctional piperidinamide derivatives as σ
    European journal of medicinal chemistry, 2021, Dec-15, Volume: 226

    Topics: Acetic Acid; Amides; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Formaldehyde; Guin

2021
Evaluation of Rhodojaponin III from Rhododendron molle G. Don on oral antinociceptive activity, mechanism of action, and subacute toxicity in rodents.
    Journal of ethnopharmacology, 2022, Aug-10, Volume: 294

    Topics: Acetic Acid; Analgesics; Animals; Diterpenes; Molecular Docking Simulation; Neuralgia; Nociceptive P

2022
PK/PD analysis of trazodone and gabapentin in neuropathic pain rodent models: Translational PK-PD modeling from nonclinical to clinical development.
    Clinical and translational science, 2023, Volume: 16, Issue:4

    Topics: Acetic Acid; Analgesics; Animals; Gabapentin; Humans; Mice; Models, Biological; Neuralgia; Rodentia;

2023
Antinociceptive Effect of Spirocyclopiperazinium Salt Compound DXL-A-24 and the Underlying Mechanism.
    Neurochemical research, 2019, Volume: 44, Issue:12

    Topics: Acetic Acid; Analgesics; Animals; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Prot

2019
Neuropathic insult increases the responsiveness to acetic acid in mice.
    Behavioural pharmacology, 2019, Volume: 30, Issue:6

    Topics: Acetic Acid; Animals; Conditioning, Classical; Disease Models, Animal; Hyperalgesia; Male; Mice; Mic

2019
Pentoxifylline modifies central and peripheral vagal mechanism in acute and chronic pain models.
    Folia medica Cracoviensia, 2012, Volume: 52, Issue:1-2

    Topics: Acetic Acid; Acute Pain; Animals; Anti-Inflammatory Agents; Chronic Pain; Cytokines; Hyperalgesia; I

2012
Analgesic effects of Huwentoxin-IV on animal models of inflammatory and neuropathic pain.
    Protein and peptide letters, 2014, Volume: 21, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Formaldehyde; Inflammati

2014
TRR469, a potent A(1) adenosine receptor allosteric modulator, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice.
    Neuropharmacology, 2014, Volume: 81

    Topics: Acetic Acid; Allosteric Regulation; Analgesics; Animals; Catalepsy; CHO Cells; Cricetinae; Cricetulu

2014
Synthesis and analgesic effects of μ-TRTX-Hhn1b on models of inflammatory and neuropathic pain.
    Toxins, 2014, Aug-13, Volume: 6, Issue:8

    Topics: Acetic Acid; Analgesics; Animals; Disease Models, Animal; Formaldehyde; HEK293 Cells; Humans; Inflam

2014
Potential analgesic effects of a novel N-acylethanolamine acid amidase inhibitor F96 through PPAR-α.
    Scientific reports, 2015, Aug-27, Volume: 5

    Topics: Acetic Acid; Amidohydrolases; Analgesics; Animals; Disease Models, Animal; Ear; Edema; Enzyme Inhibi

2015
Anticonvulsant and antinociceptive activity of new amides derived from 3-phenyl-2,5-dioxo-pyrrolidine-1-yl-acetic acid in mice.
    European journal of pharmacology, 2016, Jun-15, Volume: 781

    Topics: Acetic Acid; Amides; Analgesics; Animals; Anticonvulsants; Binding Sites; Calcium Channels; Male; Mi

2016
Profound reduction of somatic and visceral pain in mice by intrathecal administration of the anti-migraine drug, sumatriptan.
    Pain, 2008, Oct-31, Volume: 139, Issue:3

    Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Blood-Brain Barrier; Carrageenan; Drug Evaluation, P

2008
Gelsenicine from Gelsemium elegans attenuates neuropathic and inflammatory pain in mice.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:12

    Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Behavior, Animal; Drugs, Chinese Herbal; Formaldehyde;

2011
Antinociceptive and anti-inflammatory effects of octacosanol from the leaves of Sabicea grisea var. grisea in mice.
    International journal of molecular sciences, 2012, Volume: 13, Issue:2

    Topics: Acetic Acid; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Anti-Inflammatory Agents;

2012
Visceral, inflammatory and neuropathic pain in glycine receptor alpha 3-deficient mice.
    Neuroreport, 2005, Dec-19, Volume: 16, Issue:18

    Topics: Acetic Acid; Animals; Formaldehyde; Inflammation; Irritants; Mice; Mice, Mutant Strains; Neuralgia;

2005
Anti-inflammatory, anti-nociceptive and antipyretic effects of extracts of Phrygilanthus acutifolius flowers.
    Journal of ethnopharmacology, 2006, Nov-24, Volume: 108, Issue:2

    Topics: Acetic Acid; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-

2006