Page last updated: 2024-10-16

acetic acid and Metaplasia

acetic acid has been researched along with Metaplasia in 19 studies

Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.

Metaplasia: A condition in which there is a change of one adult cell type to another similar adult cell type.

Research Excerpts

ExcerptRelevanceReference
"Our aim was to evaluate the ability of blue laser imaging (BLI) combined with acetic acid (BLI-AA) to detect gastric intestinal metaplasia (GIM)."7.91Blue laser imaging with acetic acid enhancement improved the detection rate of gastric intestinal metaplasia. ( Chen, H; Li, C; Liu, Y; Lu, Y; Wu, Q; Wu, X, 2019)
" Aim To determine whether enhanced magnification endoscopy using acetic acid instillation improves diagnostic accuracy of specialized intestinal metaplasia/dysplasia in Barrett's oesophagus."7.73Acetic acid-enhanced magnification endoscopy in the diagnosis of specialized intestinal metaplasia, dysplasia and early cancer in Barrett's oesophagus. ( Anagnostopoulos, GK; Badreldin, R; Campbell, E; Foley, S; Fortun, PJ; Hawkey, CJ; James, M; Kaye, P; Ragunath, K; Samuel, S; Shonde, A, 2006)
"We examined the detection rate of the specialized intestinal metaplasia/dysplasia in 64 consecutive patients with Barrett's oesophagus using acetic acid to enhance mucosal pit patterns."7.73Acetic acid-enhanced magnification endoscopy in the diagnosis of specialized intestinal metaplasia, dysplasia and early cancer in Barrett's oesophagus. ( Anagnostopoulos, GK; Badreldin, R; Campbell, E; Foley, S; Fortun, PJ; Hawkey, CJ; James, M; Kaye, P; Ragunath, K; Samuel, S; Shonde, A, 2006)
"Our aim was to evaluate the ability of blue laser imaging (BLI) combined with acetic acid (BLI-AA) to detect gastric intestinal metaplasia (GIM)."3.91Blue laser imaging with acetic acid enhancement improved the detection rate of gastric intestinal metaplasia. ( Chen, H; Li, C; Liu, Y; Lu, Y; Wu, Q; Wu, X, 2019)
" Aim To determine whether enhanced magnification endoscopy using acetic acid instillation improves diagnostic accuracy of specialized intestinal metaplasia/dysplasia in Barrett's oesophagus."3.73Acetic acid-enhanced magnification endoscopy in the diagnosis of specialized intestinal metaplasia, dysplasia and early cancer in Barrett's oesophagus. ( Anagnostopoulos, GK; Badreldin, R; Campbell, E; Foley, S; Fortun, PJ; Hawkey, CJ; James, M; Kaye, P; Ragunath, K; Samuel, S; Shonde, A, 2006)
"We examined the detection rate of the specialized intestinal metaplasia/dysplasia in 64 consecutive patients with Barrett's oesophagus using acetic acid to enhance mucosal pit patterns."3.73Acetic acid-enhanced magnification endoscopy in the diagnosis of specialized intestinal metaplasia, dysplasia and early cancer in Barrett's oesophagus. ( Anagnostopoulos, GK; Badreldin, R; Campbell, E; Foley, S; Fortun, PJ; Hawkey, CJ; James, M; Kaye, P; Ragunath, K; Samuel, S; Shonde, A, 2006)
"Thirty-one patients with Barrett's esophagus or visible columnar-lined lower esophagus."2.72Acetic acid-guided biopsies after magnifying endoscopy compared with random biopsies in the detection of Barrett's esophagus: a prospective randomized trial with crossover design. ( Bender, A; Herrmann, G; Hoffman, A; Jung, M; Kiesslich, R; Nafe, B; Neurath, MF, 2006)
"Intestinal metaplasia of Barrett's esophagus is pre-cancerous lesion and it is important to diagnose intestinal metaplasia by endoscopic examination."2.43[Magnification endoscopy diagnosis of Barrett's esophagus with methylene blue and acetic acid]. ( Nakamura, A; Sekine, A; Yagi, K, 2005)
"In diseases such as Barrett's esophagus and celiac disease, the mucosal abnormality is patchy or irregular, highlighting the need for targeted biopsies."2.42Enhanced magnification endoscopy in the upper gastrointestinal tract. ( Ehrlich, EE; Guelrud, M, 2004)
"The diagnosis of Barrett's esophagus (BE) is disturbed by numerous factors, including correct gastroesophageal junction judgment, the initial location of the Z-line and the biopsy result above it."1.48Circular stripes were more common in Barrett's esophagus after acetic acid staining. ( Dong, L; Fang, L; Ma, S; Sun, Y; Wang, J, 2018)
"This study showed that screening of cervical cancer by visual inspection is workable at CSCOM level."1.35[Extension of cervix cancer screening by visual methods to the community health centres in the district of Bamako]. ( Bayo, S; Dembele, Y; Diallo, D; Diané, M; Diarra, MH; Dolo, AI; Kaloga, I; Kamaté, B; Keita, B; Mariko, H; Ouattara, AT; Sacko, R; Sanogo, A; Tall, K; Teguete, B; Togola, B; Toure, M; Traoré, AC; Traoré, CB; Traoré, M; Traore, Y, 2008)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.53)18.2507
2000's10 (52.63)29.6817
2010's5 (26.32)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Ji, R1
Liu, J1
Zhang, MM1
Li, YY1
Zuo, XL1
Wang, X1
Li, YQ1
Teal, E1
Dua-Awereh, M1
Hirshorn, ST1
Zavros, Y1
Sun, Y1
Ma, S1
Fang, L1
Wang, J1
Dong, L1
Chen, H1
Wu, X1
Liu, Y1
Wu, Q1
Lu, Y1
Li, C1
Song, KH1
Hwang, JA1
Kim, SM1
Ko, HS1
Kang, MK1
Ryu, KH1
Koo, HS1
Lee, TH1
Huh, KC1
Choi, YW1
Kang, YW1
Sha, J1
Wang, P1
Zhu, B1
Zhu, M1
Li, X1
Gao, F1
Kamaté, B1
Traoré, CB1
Diallo, D1
Sacko, R1
Toure, M1
Keita, B1
Teguete, B1
Traore, Y1
Diarra, MH1
Ouattara, AT1
Traoré, AC1
Mariko, H1
Dembele, Y1
Togola, B1
Tall, K1
Sanogo, A1
Diané, M1
Kaloga, I1
Traoré, M1
Dolo, AI1
Bayo, S1
Kikuchi, M1
Nagata, H1
Watanabe, N1
Watanabe, H1
Tatemichi, M1
Hibi, T1
Toyoda, H1
Rubio, C1
Befrits, R1
Hamamoto, N1
Adachi, Y1
Jaramillo, E1
Guelrud, M2
Ehrlich, EE1
Yagi, K1
Nakamura, A1
Sekine, A1
Fortun, PJ1
Anagnostopoulos, GK1
Kaye, P1
James, M1
Foley, S1
Samuel, S1
Shonde, A1
Badreldin, R1
Campbell, E1
Hawkey, CJ1
Ragunath, K1
Réaud, S1
Croue, A1
Boyer, J1
Hoffman, A1
Kiesslich, R1
Bender, A1
Neurath, MF1
Nafe, B1
Herrmann, G1
Jung, M1
Conio, M1
Canto, MI1
Shimizu, T1
Akamatsu, T1
Sugiyama, A1
Ota, H1
Katsuyama, T1
Sankaranarayanan, R1
Shyamalakumary, B1
Wesley, R1
Sreedevi Amma, N1
Parkin, DM1
Nair, MK1
Herrera, I1
Essenfeld, H1
Castro, J1
Antonioli, DA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Acetic Acid Chromoendoscopy for Judging Extent of Gastric Intestinal Metaplasia[NCT01499576]126 participants (Actual)Interventional2011-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Agreement of Acetic Acid Chromoendoscopic Reading Between the Two Endoscopists

"The findings of chromoendoscopy will be interpretated by two endoscoipists (read as positive or negative finding) independently.~We calculate the Kappa index of agreement for the acetic acid chromoendoscopy." (NCT01499576)
Timeframe: One month after the completion of the study

InterventionKappa index of agreement (Number)
Acetic Acid Spraying0.808

Number of Participants With Adverse Events

Number of Participants with Adverse Events. Assess kind of side effect and severity. Measured by interview with a physician, just after the procedure and 1weak later. (NCT01499576)
Timeframe: up to 1week after the acetic acid chromoendoscopy

Interventionparticipants (Number)
Epigastric discomfortNeck discomfort
Acetic Acid Spraying92

Percent Agreement Between Acetic Acid Chromoendoscopy and Endoscopic Biopsy

Endoscopist judges the presence and the extent of gastric intestinal metaplasia during acetic acid chromoendoscopy. Endoscopist perform five endoscopic biopsies according to the protocol. The degree of agreement between the chromoendoscopy and the endoscopic biopsy is assessed as %. (NCT01499576)
Timeframe: 3 months after the completion of the study (a pathologist reviewed all the biopsy slide)

Interventionpercentage of lesions (Number)
Overall SensitivityOverall SpecificityOverall AccuracyBody SensitivityBody SpecificityBody AccuracyAntrum SensitivityAntrum SpecificityAntrum Accuracy
Acetic Acid Spraying78.594.489.267.194.789.480.993.688.4

Reviews

3 reviews available for acetic acid and Metaplasia

ArticleYear
Role of metaplasia during gastric regeneration.
    American journal of physiology. Cell physiology, 2020, 12-01, Volume: 319, Issue:6

    Topics: Acetic Acid; Animals; Gastric Mucosa; Humans; Metaplasia; Regeneration; Stomach

2020
Enhanced magnification endoscopy in the upper gastrointestinal tract.
    Gastrointestinal endoscopy clinics of North America, 2004, Volume: 14, Issue:3

    Topics: Acetic Acid; Barrett Esophagus; Cardia; Celiac Disease; Endoscopy, Digestive System; Humans; Metapla

2004
[Magnification endoscopy diagnosis of Barrett's esophagus with methylene blue and acetic acid].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63, Issue:8

    Topics: Acetic Acid; Barrett Esophagus; Esophagoscopes; Esophagoscopy; Esophagus; Humans; Metaplasia; Methyl

2005

Trials

3 trials available for acetic acid and Metaplasia

ArticleYear
Optical enhancement imaging versus acetic acid for detecting gastric intestinal metaplasia: A randomized, comparative trial.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2020, Volume: 52, Issue:6

    Topics: Acetic Acid; Adult; Aged; Biopsy; Female; Gastritis, Atrophic; Gastroscopy; Humans; Indicators and R

2020
Diagnostic accuracy of magnifying chromoendoscopy with detection of intestinal metaplasia and dysplasia using acetic acid in Barrett's esophagus.
    Gastroenterologie clinique et biologique, 2006, Volume: 30, Issue:2

    Topics: Acetic Acid; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Biopsy; Endoscopy, Gastrointestinal;

2006
Acetic acid-guided biopsies after magnifying endoscopy compared with random biopsies in the detection of Barrett's esophagus: a prospective randomized trial with crossover design.
    Gastrointestinal endoscopy, 2006, Volume: 64, Issue:1

    Topics: Acetic Acid; Adolescent; Adult; Aged; Barrett Esophagus; Biopsy; Color; Cross-Over Studies; Endoscop

2006

Other Studies

13 other studies available for acetic acid and Metaplasia

ArticleYear
Circular stripes were more common in Barrett's esophagus after acetic acid staining.
    BMC gastroenterology, 2018, Jan-25, Volume: 18, Issue:1

    Topics: Acetic Acid; Barrett Esophagus; Esophageal Mucosa; Esophagogastric Junction; Esophagoscopy; Female;

2018
Blue laser imaging with acetic acid enhancement improved the detection rate of gastric intestinal metaplasia.
    Lasers in medical science, 2019, Volume: 34, Issue:3

    Topics: Acetic Acid; Aged; Biopsy; Female; Gastroscopy; Humans; Imaging, Three-Dimensional; Lasers; Male; Me

2019
Acetic acid chromoendoscopy for determining the extent of gastric intestinal metaplasia.
    Gastrointestinal endoscopy, 2017, Volume: 85, Issue:2

    Topics: Acetic Acid; Adult; Aged; Endoscopy, Digestive System; Female; Humans; Indicators and Reagents; Male

2017
Acetic Acid Enhanced Narrow Band Imaging for the Diagnosis of Gastric Intestinal Metaplasia.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Acetic Acid; Adult; Biopsy; Demography; Female; Gastroscopy; Humans; Intestines; Male; Metaplasia; M

2017
[Extension of cervix cancer screening by visual methods to the community health centres in the district of Bamako].
    Le Mali medical, 2008, Volume: 23, Issue:4

    Topics: Acetic Acid; Adenocarcinoma; Adult; Biopsy; Carcinoma, Squamous Cell; Coloring Agents; Community Hea

2008
Altered expression of a putative progenitor cell marker DCAMKL1 in the rat gastric mucosa in regeneration, metaplasia and dysplasia.
    BMC gastroenterology, 2010, Jun-18, Volume: 10

    Topics: Acetic Acid; Animals; Biomarkers; Cell Proliferation; Disease Models, Animal; Doublecortin Protein;

2010
Detection of intestinal metaplasia in distal esophagus and esophagogastric junction by enhanced-magnification endoscopy.
    Gastrointestinal endoscopy, 2004, Volume: 59, Issue:1

    Topics: Acetic Acid; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Endoscopy, Gastrointestinal; Esophag

2004
Acetic acid-enhanced magnification endoscopy in the diagnosis of specialized intestinal metaplasia, dysplasia and early cancer in Barrett's oesophagus.
    Alimentary pharmacology & therapeutics, 2006, Mar-15, Volume: 23, Issue:6

    Topics: Acetic Acid; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Endoscopy, Gastroint

2006
Esophageal chromoendoscopy in Barrett's esophagus: "cons".
    Gastrointestinal endoscopy, 2006, Volume: 64, Issue:1

    Topics: Acetic Acid; Barrett Esophagus; Biopsy; Color; Endoscopy, Gastrointestinal; Humans; Image Enhancemen

2006
Acetic-acid chromoendoscopy for Barrett's esophagus: the "pros".
    Gastrointestinal endoscopy, 2006, Volume: 64, Issue:1

    Topics: Acetic Acid; Barrett Esophagus; Carcinoma in Situ; Color; Endoscopy, Gastrointestinal; Humans; Image

2006
Helicobacter pylori and the surface mucous gel layer of the human stomach.
    Helicobacter, 1996, Volume: 1, Issue:4

    Topics: Acetic Acid; Anti-Bacterial Agents; Chloroform; Drug Therapy, Combination; Eosine Yellowish-(YS); Et

1996
Visual inspection with acetic acid in the early detection of cervical cancer and precursors.
    International journal of cancer, 1999, Jan-05, Volume: 80, Issue:1

    Topics: Acetic Acid; Adult; Carcinoma in Situ; Cervix Uteri; Colposcopy; Educational Status; Female; Humans;

1999
Intestinal metaplasia of the gastric cardia: A prospective study with enhanced magnification endoscopy.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:3

    Topics: Acetic Acid; Adolescent; Adult; Aged; Cardia; Female; Gastric Mucosa; Gastroscopy; Humans; Image Enh

2002