acetic acid has been researched along with Innate Inflammatory Response in 245 studies
Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It was aimed to induce a new experimental colitis model by using acetic acid and trinitrobenzene sulphonic acid together and to investigate the severity of inflammation biochemically and histopathologically in comparison with other models." | 8.31 | A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid. ( Astarcı, HM; Buğdaycı, G; Cinpolat, HY; Şengül, N, 2023) |
| "Fifty-six Wistar albino male rats were randomly divided into 4 groups as control, acetic acid, trinitrobenzene sulphonic acid, and combined groups, and the animals were sacrificed following the induction of colitis on the third day and on the seventh day." | 8.31 | A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid. ( Astarcı, HM; Buğdaycı, G; Cinpolat, HY; Şengül, N, 2023) |
| "The acetic acid model forms acute colitis." | 8.31 | A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid. ( Astarcı, HM; Buğdaycı, G; Cinpolat, HY; Şengül, N, 2023) |
| " The objective of the present study is to elucidate for the first time the effects of Cotinus coggygria (CC) ethanol extract (CCE) on colonic structure and inflammation of acetic acid-induced ulcerative colitis in rats." | 8.31 | Cotinus coggygria Scop. Attenuates Acetic Acid-Induced Colitis in Rats by Regulation of Inflammatory Mediators. ( Akakın, D; Bitiş, L; Çevik, Ö; Ertaş, B; Kayalı, DG; Şen, A; Şener, G; Yıldırım, A, 2023) |
| " The oral administration of HA-BUD-ES-NPs in an acetic acid induced colitis rat model significantly mitigated the symptoms of IBD, and improved BUD therapeutic efficacy compared to drug suspension." | 8.31 | Targeted delivery of budesonide in acetic acid induced colitis: impact on miR-21 and E-cadherin expression. ( Allam, EA; El-Kamel, AH; El-Moslemany, RM; Elkafrawy, H; Seoudi, SS, 2023) |
| "In this study, the therapeutic effect of quinic acid (QA), which has anti-inflammatory activity, was investigated on acetic acid-induced colitis in male Wistar rats." | 8.31 | Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways. ( Amini-Khoei, H; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M; Sabzevary-Ghahfarokhi, M, 2023) |
| "Ulcerative colitis (UC) was induced in rats by acetic acid intrarectally, and the protective effects of QA in 10, 30, 60, and 100 mg/kg doses were investigated." | 8.31 | Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways. ( Amini-Khoei, H; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M; Sabzevary-Ghahfarokhi, M, 2023) |
| " In this study, the regulatory effect of EGCG on more complex oral microbial systems was further explored through a mouse model of acetic acid-induced oral inflammation." | 8.31 | Epigallocatechin gallate (EGCG) alleviates the inflammatory response and recovers oral microbiota in acetic acid-induced oral inflammation mice. ( Chen, P; Chen, S; Cheng, Y; Chu, Q; Fan, F; Feng, X; Gong, S; Hu, H; Lv, H; Pan, Y; Zhou, S, 2023) |
| "The current study was performed to evaluate the therapeutic impacts of the juglone in acetic acid-induced colitis in male Wistar rats." | 8.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| " Colitis was induced in 36 male Wistar rats (n = 6), except in the sham group, 1 ml of acetic acid 4% was administered intrarectally." | 8.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| " Juglone attenuated colitis symptoms, reduced inflammation cytokines, declined neutrophil infiltration, and suppressed IL- 1β and TNF-α expressions in acetic acid-induced colitis rats." | 8.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Juglone exhibited anti-inflammatory and antioxidant effects in the experimental colitis model and could be a therapeutic candidate for IBD." | 8.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Macroscopic and microscopic assessments revealed that juglone significantly decreased colonic tissue damage and inflammation at 150 mg/kg." | 8.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Fifty rats were randomly separated into five groups (n = 10) with different durations (30 s, 5, 10, and 20 min) of exposure of the colon to 4% acetic acid and colitis was investigated for 0-9 days." | 8.12 | Improving Animal Model of Induced Colitis by Acetic Acid in Terms of Fibrosis and Inflammation Incidence in the Colon. ( Babaei, A; Bahrami, G; Madani, H; Malekshahi, H; Miraghaee, S, 2022) |
| " The anthocyanidin effects were examined in gastric ulcer mouse models induced by ethanol, non-steroidal anti-inflammatory drugs (NSAIDs), ischemia-reperfusion (IR), acetic acid and duodenal ulcer induced by polypharmacy." | 8.02 | Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation. ( Dos Santos, RC; Fagundes, FL; Pereira, QC; Zarricueta, ML, 2021) |
| " The effect of the extract on acute inflammation was analyzed by increasing vascular permeability via acetic acid and xylene induced ear edema among mice." | 8.02 | Effect of Nectaroscordum koelzi Methanolic Extract on Acute and Chronic Inflammation in Male Mice. ( Alipour, M; Hasanvand, KH; Khaksarian, M; Mahmoudvand, H; Nadri, S; Naizi, M, 2021) |
| "The findings showed that the extract was effective on acute inflammation induced by acetic acid in mice." | 8.02 | Effect of Nectaroscordum koelzi Methanolic Extract on Acute and Chronic Inflammation in Male Mice. ( Alipour, M; Hasanvand, KH; Khaksarian, M; Mahmoudvand, H; Nadri, S; Naizi, M, 2021) |
| "7 cells stimulated with LPS (1μg/mL) and in in-vivo study, colitis was induced by intra rectal administration of 4% Acetic acid." | 8.02 | Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats. ( S K, K; V S, A, 2021) |
| " Phloretin exerted ameliorative effect in both pre and post-treatment groups by restoring plasma ALP and LDH level and reduce inflammatory markers like myeloperoxidase, nitric oxide and eosinophil peroxidase level as well as downregulates colon ICAM-1 gene in acetic acid induced ulcerative colitis in rats." | 8.02 | Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats. ( S K, K; V S, A, 2021) |
| " In this study, we evaluated the ability of goat whey to prevent intestinal inflammation in the experimental model of acetic acid-induced rats and compared it to sulfasalazine." | 7.83 | Goat whey ameliorates intestinal inflammation on acetic acid-induced colitis in rats. ( Antonino de Assis, PO; Antunes de Araújo, A; Araújo, DFS; Formiga de Sousa, YR; Gálvez, J; Guerra, GCB; Júnior, RFA; Nunes de Medeiros, A; Pintado, MME; Queiroga, RCRDE, 2016) |
| " Additionally, we evaluated the analgesic effect on the acetic acid-induced writhing response and the inhibitory activity on xylene-induced ear edema in mice." | 7.81 | Anti-inflammatory and analgesic effects of pyeongwisan on LPS-stimulated murine macrophages and mouse models of acetic acid-induced writhing response and xylene-induced ear edema. ( Cho, WK; Gu, MJ; Ha, JH; Jeong, YH; Ma, JY; Oh, YC, 2015) |
| " Additionally, anti-inflammatory function of gelsolin (8 mg/mouse) compared with anti-inflammatory drug diclofenac sodium (10 mg/kg)] was confirmed in the carrageenan injection induced paw edema where latter was measured by vernier caliper and fluorescent tomography imaging." | 7.81 | Analgesic and Anti-Inflammatory Properties of Gelsolin in Acetic Acid Induced Writhing, Tail Immersion and Carrageenan Induced Paw Edema in Mice. ( Chopra, BS; Choudhary, V; Garg, R; Gupta, AK; Khatri, N; Parasar, D; Sagar, A, 2015) |
| " The aim of the present study was to investigate the potential protective effect of l-arginine (Arg; nitric oxide precursor) and aminoguanidine (inducible nitric oxide synthase inhibitor) against acetic acid (AA)-induced colitis in rats, and the potential role of NF-κB." | 7.80 | L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65. ( Farghaly, HS; Thabit, RH, 2014) |
| " Opioid coadministration had a synergistic effect in the acute tonic pain (acetic acid writhing test), acute phasic pain (tail flick test) and inflammatory pain (orofacial formalin test)." | 7.79 | Systemic synergism between codeine and morphine in three pain models in mice. ( Miranda, HF; Noriega, V; Prieto, JC; Sierralta, F; Zepeda, RJ, 2013) |
| "Thirty rats were divided into five groups: a control group, an acetic acid-induced colitis group, a group treated with melatonin before colitis induction, a group treated short-term after colitis induction, and a group treated long-term after colitis induction." | 7.79 | The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat. ( Blann, A; El Sers, DA; Idriss, NK; Jaumdally, RJ; Sayyed, HG, 2013) |
| "Melatonin is effective in prevention and short-term treatment of the inflammatory process in acetic-acid induced colitis whereas the benefit of long-term treatment is unclear." | 7.79 | The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat. ( Blann, A; El Sers, DA; Idriss, NK; Jaumdally, RJ; Sayyed, HG, 2013) |
| "Melatonin may be involved in gastrointestinal tract physiology and could affect inflammation-related gastrointestinal disorders." | 7.79 | The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat. ( Blann, A; El Sers, DA; Idriss, NK; Jaumdally, RJ; Sayyed, HG, 2013) |
| ", synergistic) in preclinical models of visceral and inflammatory pain, specifically acetic acid-induced writhing in mice and carrageenan-induced thermal hyperalgesia and mechanical allodynia in rats." | 7.74 | Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents. ( Jones, CK; Peters, SC; Shannon, HE, 2007) |
| " Isobolographic analysis of the effects of duloxetine in combination with ibuprofen revealed a significant synergistic (greater than additive) interaction between duloxetine and ibuprofen both for reducing acetic acid-induced writhing and carrageenan-induced thermal hyperalgesia, but were additive for reversing mechanical allodynia." | 7.74 | Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents. ( Jones, CK; Peters, SC; Shannon, HE, 2007) |
| "Our data indicate that duloxetine and ibuprofen have synergistic efficacy in a visceral and an inflammatory pain model in rodents, and suggest that duloxetine and ibuprofen in combination may provide a useful approach to the clinical treatment of persistent pain, particularly inflammation-related pain." | 7.74 | Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents. ( Jones, CK; Peters, SC; Shannon, HE, 2007) |
| "Colitis was induced by intracolonic administration of acetic acid (5%) in Sprague-Dawley rats (200-250 g)." | 7.73 | Oxytocin ameliorates oxidative colonic inflammation by a neutrophil-dependent mechanism. ( Ercan, F; Gedik, N; Işeri, SO; Sağlam, B; Sener, G; Yeğen, BC, 2005) |
| "We previously discovered that a 4-wk course of indomethacin delivered to rats with acetic acid ulcers resulted in production of "unhealed gastric ulcers" that persisted for up to 12 wks after treatment cessation." | 7.72 | Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats. ( Amagase, K; Okabe, S; Tsukimi, Y; Yokota, M, 2003) |
| "The present study was designed to compare the effect of leptin on acute colonic inflammation with that of acute stress exposure, which acts via the hypothalamic-pituitary-adrenal (HPA) axis." | 7.72 | The anti-inflammatory effect of leptin on experimental colitis: involvement of endogenous glucocorticoids. ( Bozkurt, A; Cakir, B; Ercan, F; Yeğen, BC, 2004) |
| "The antihyperalgesic effect of pentoxifylline was investigated in three experimental pain models." | 7.72 | Antihyperalgesic effect of pentoxifylline on experimental inflammatory pain. ( Benevides, VM; Brito, GA; Cunha, FQ; da Rocha, FA; Ferreira, SH; Poole, S; Ribeiro, RA; Sachs, D; Vale, ML, 2004) |
| "The methanol extract of the florets of Tagetes patula (MEFTP) inhibited acute and chronic inflammation in mice and rats." | 7.71 | Effect of methanol extract from flower petals of Tagetes patula L. on acute and chronic inflammation model. ( Evans, FJ; Kasahara, Y; Khan, MT; Kitanaka, S; Yasukawa, K, 2002) |
| "Colitis was evoked by a single transrectal injection of 1 ml of 4 % acetic acid." | 5.91 | Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia activity. ( Ahmed, KA; Elbaz, EM; Essam, RM; Safwat, MH, 2023) |
| "Ulcerative colitis is a chronic inflammation of the colon." | 5.91 | Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue. ( Amini-Khoei, H; AnjomShoa, M; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2023) |
| "To induce ulcerative colitis, animals received 0." | 5.91 | Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue. ( Amini-Khoei, H; AnjomShoa, M; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2023) |
| "All juglone-treated groups reduced the NF-κB levels compared to the control group (p < 0." | 5.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Juglone is a phenolic bioactive compound with antimicrobial, antitumour, antioxidant, and anti-inflammatory characteristics." | 5.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Juglone was extracted from Pterocarya fraxinifolia via maceration method." | 5.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Colitis was induced in 36 male Wistar rats (n = 6), except in the sham group, 1 ml of acetic acid 4% was administered intrarectally." | 5.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Ulcerative colitis is a chronic inflammatory disease, profoundly affecting the patient's quality of life and is associated with various complications." | 5.72 | Linagliptin ameliorates acetic acid-induced colitis via modulating AMPK/SIRT1/PGC-1α and JAK2/STAT3 signaling pathway in rats. ( El-Bahy, AAZ; El-Ghannam, MS; El-Yamany, MF; Nassar, NN; Saad, MA, 2022) |
| "Phloretin (50 mg/kg) was given orally for 3 days to Wistar rats after induction for the post-treatment group and 1 day before induction to the pre-treatment group." | 5.62 | Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats. ( S K, K; V S, A, 2021) |
| "Pretreatment with molsidomine significantly reduced disease activity index, colon mass index, colonic macroscopic and histological damage." | 5.62 | Molsidomine alleviates acetic acid-induced colitis in rats by reducing oxidative stress, inflammation and apoptosis. ( El-Kashef, DH; Mohamed, NI; Suddek, GM, 2021) |
| "Curcumin has proven to be beneficial in the prevention and treatment of a number of inflammatory diseases, but due its poor bioavailability, the therapeutic applications are limited." | 5.56 | Anti-Ulcerative Effect of Curcumin-Galactomannoside Complex on Acetic Acid-Induced Experimental Model by Inhibiting Inflammation and Oxidative Stress. ( Asha, S; Girishkumar, B; Grace, J; Jose, SP; Krishnakumar, IM; Ratheesh, M; Sandya, S; Sheethal, S, 2020) |
| "The pathogenesis of ulcerative colitis (UC) is related to reduced antioxidant capacity and increased inflammatory processes." | 5.56 | Anti-Ulcerative Effect of Curcumin-Galactomannoside Complex on Acetic Acid-Induced Experimental Model by Inhibiting Inflammation and Oxidative Stress. ( Asha, S; Girishkumar, B; Grace, J; Jose, SP; Krishnakumar, IM; Ratheesh, M; Sandya, S; Sheethal, S, 2020) |
| "Colitis was induced in rats by acetic acid and the rats were divided into four groups where one group served as experimental control and the other groups were treated with two doses of methanol extract of dried latex of C." | 5.51 | Protection afforded by methanol extract of Calotropis procera latex in experimental model of colitis is mediated through inhibition of oxidative stress and pro-inflammatory signaling. ( Das, P; Kumar, VL; Pandey, A; Verma, S, 2019) |
| "Ulcers were induced by serosal application of 80 % acetic acid to the stomach of rats anaesthetized with 50 mg/kg thiopentone sodium and treatment was given three times daily." | 5.46 | Effects of quinine on gastric ulcer healing in Wistar rats. ( Adeniyi, OS; Friday, ET; Makinde, OV; Olaleye, SB, 2017) |
| "Colitis was induced by intrarectal inoculation of rats with 4% acetic acid for three consecutive days." | 5.40 | L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65. ( Farghaly, HS; Thabit, RH, 2014) |
| "Oleanolic acid (OA) is a triterpenoid known for its anti-inflammatory and anti-cancer properties; however, the anti-inflammatory effects of OA on lipopolysaccharide (LPS)-mediated pro-inflammatory responses have not been studied." | 5.39 | Anti-inflammatory effects of oleanolic acid on LPS-induced inflammation in vitro and in vivo. ( Bae, JS; Ku, SK; Lee, W; Song, KS; Yang, EJ, 2013) |
| "Pentoxifylline (PTX) has strong antyinflamatory effects, decreases TNF-alpha and other proinflammatory cytokines production." | 5.38 | Pentoxifylline modifies central and peripheral vagal mechanism in acute and chronic pain models. ( Dobrogowski, J; Nowak, Ł; Thor, PJ; Wordliczek, J; Zurowski, D, 2012) |
| "Colitis was induced by intracolonic administration of acetic acid (5%) in Sprague-Dawley rats (200-250 g)." | 5.33 | Oxytocin ameliorates oxidative colonic inflammation by a neutrophil-dependent mechanism. ( Ercan, F; Gedik, N; Işeri, SO; Sağlam, B; Sener, G; Yeğen, BC, 2005) |
| "Pentoxifylline did not inhibit the nociceptive response in the hot plate test in mice." | 5.32 | Antihyperalgesic effect of pentoxifylline on experimental inflammatory pain. ( Benevides, VM; Brito, GA; Cunha, FQ; da Rocha, FA; Ferreira, SH; Poole, S; Ribeiro, RA; Sachs, D; Vale, ML, 2004) |
| "It was aimed to induce a new experimental colitis model by using acetic acid and trinitrobenzene sulphonic acid together and to investigate the severity of inflammation biochemically and histopathologically in comparison with other models." | 4.31 | A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid. ( Astarcı, HM; Buğdaycı, G; Cinpolat, HY; Şengül, N, 2023) |
| "Fifty-six Wistar albino male rats were randomly divided into 4 groups as control, acetic acid, trinitrobenzene sulphonic acid, and combined groups, and the animals were sacrificed following the induction of colitis on the third day and on the seventh day." | 4.31 | A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid. ( Astarcı, HM; Buğdaycı, G; Cinpolat, HY; Şengül, N, 2023) |
| "The acetic acid model forms acute colitis." | 4.31 | A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid. ( Astarcı, HM; Buğdaycı, G; Cinpolat, HY; Şengül, N, 2023) |
| " The objective of the present study is to elucidate for the first time the effects of Cotinus coggygria (CC) ethanol extract (CCE) on colonic structure and inflammation of acetic acid-induced ulcerative colitis in rats." | 4.31 | Cotinus coggygria Scop. Attenuates Acetic Acid-Induced Colitis in Rats by Regulation of Inflammatory Mediators. ( Akakın, D; Bitiş, L; Çevik, Ö; Ertaş, B; Kayalı, DG; Şen, A; Şener, G; Yıldırım, A, 2023) |
| " The oral administration of HA-BUD-ES-NPs in an acetic acid induced colitis rat model significantly mitigated the symptoms of IBD, and improved BUD therapeutic efficacy compared to drug suspension." | 4.31 | Targeted delivery of budesonide in acetic acid induced colitis: impact on miR-21 and E-cadherin expression. ( Allam, EA; El-Kamel, AH; El-Moslemany, RM; Elkafrawy, H; Seoudi, SS, 2023) |
| "In this study, the therapeutic effect of quinic acid (QA), which has anti-inflammatory activity, was investigated on acetic acid-induced colitis in male Wistar rats." | 4.31 | Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways. ( Amini-Khoei, H; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M; Sabzevary-Ghahfarokhi, M, 2023) |
| "Ulcerative colitis (UC) was induced in rats by acetic acid intrarectally, and the protective effects of QA in 10, 30, 60, and 100 mg/kg doses were investigated." | 4.31 | Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways. ( Amini-Khoei, H; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M; Sabzevary-Ghahfarokhi, M, 2023) |
| " In this study, the regulatory effect of EGCG on more complex oral microbial systems was further explored through a mouse model of acetic acid-induced oral inflammation." | 4.31 | Epigallocatechin gallate (EGCG) alleviates the inflammatory response and recovers oral microbiota in acetic acid-induced oral inflammation mice. ( Chen, P; Chen, S; Cheng, Y; Chu, Q; Fan, F; Feng, X; Gong, S; Hu, H; Lv, H; Pan, Y; Zhou, S, 2023) |
| "The current study was performed to evaluate the therapeutic impacts of the juglone in acetic acid-induced colitis in male Wistar rats." | 4.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| " Colitis was induced in 36 male Wistar rats (n = 6), except in the sham group, 1 ml of acetic acid 4% was administered intrarectally." | 4.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| " Juglone attenuated colitis symptoms, reduced inflammation cytokines, declined neutrophil infiltration, and suppressed IL- 1β and TNF-α expressions in acetic acid-induced colitis rats." | 4.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Juglone exhibited anti-inflammatory and antioxidant effects in the experimental colitis model and could be a therapeutic candidate for IBD." | 4.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Macroscopic and microscopic assessments revealed that juglone significantly decreased colonic tissue damage and inflammation at 150 mg/kg." | 4.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| " Anti-inflammatory activity was determined by the carrageenan-induced and histamine-induce Rat paw edema in rats, analgesic activity was determined by acetic acid-Induced writhing test, formalin-induced hind paw licking in mice and Tail immersion test." | 4.12 | Evaluation of anti-inflammatory and analgesic effects of Hertia intermedia (Boiss.) Kuntze extract. ( Arslan, M; Iqbal, J; Jabbar, A; Jan, SU; Khan, Z; Mehjabeen, -; Muhammad, S; Qadir, A; Shah, PA; Soomer Khan, N; Younis, M, 2022) |
| "Fifty rats were randomly separated into five groups (n = 10) with different durations (30 s, 5, 10, and 20 min) of exposure of the colon to 4% acetic acid and colitis was investigated for 0-9 days." | 4.12 | Improving Animal Model of Induced Colitis by Acetic Acid in Terms of Fibrosis and Inflammation Incidence in the Colon. ( Babaei, A; Bahrami, G; Madani, H; Malekshahi, H; Miraghaee, S, 2022) |
| " The anthocyanidin effects were examined in gastric ulcer mouse models induced by ethanol, non-steroidal anti-inflammatory drugs (NSAIDs), ischemia-reperfusion (IR), acetic acid and duodenal ulcer induced by polypharmacy." | 4.02 | Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation. ( Dos Santos, RC; Fagundes, FL; Pereira, QC; Zarricueta, ML, 2021) |
| " The effect of the extract on acute inflammation was analyzed by increasing vascular permeability via acetic acid and xylene induced ear edema among mice." | 4.02 | Effect of Nectaroscordum koelzi Methanolic Extract on Acute and Chronic Inflammation in Male Mice. ( Alipour, M; Hasanvand, KH; Khaksarian, M; Mahmoudvand, H; Nadri, S; Naizi, M, 2021) |
| "The findings showed that the extract was effective on acute inflammation induced by acetic acid in mice." | 4.02 | Effect of Nectaroscordum koelzi Methanolic Extract on Acute and Chronic Inflammation in Male Mice. ( Alipour, M; Hasanvand, KH; Khaksarian, M; Mahmoudvand, H; Nadri, S; Naizi, M, 2021) |
| "7 cells stimulated with LPS (1μg/mL) and in in-vivo study, colitis was induced by intra rectal administration of 4% Acetic acid." | 4.02 | Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats. ( S K, K; V S, A, 2021) |
| " Phloretin exerted ameliorative effect in both pre and post-treatment groups by restoring plasma ALP and LDH level and reduce inflammatory markers like myeloperoxidase, nitric oxide and eosinophil peroxidase level as well as downregulates colon ICAM-1 gene in acetic acid induced ulcerative colitis in rats." | 4.02 | Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats. ( S K, K; V S, A, 2021) |
| "The results showed that physalin A inhibited carrageenan-induced paw edema of rats and capillary permeability of mice induced by acetic acid in vivo." | 4.02 | Anti-inflammatory action of physalin A by blocking the activation of NF-κB signaling pathway. ( Gu, J; Li, D; Li, H; Liu, P; Liu, Y; Mou, X; Qiu, F; Wang, L; Zhang, Q; Zhao, F; Zong, M, 2021) |
| " The effect of the extract in three additional in vivo models were studied: intestinal motility and diarrhea induced by ricin oil, and visceral pain induced by intracolonic administration of capsaicin." | 4.02 | Pharmacologycal activity of peperina (Minthostachys verticillata) on gastrointestinal tract. ( Bach, H; Carranza, A; Gorzalczany, SB; Rodríguez Basso, A; Zainutti, VM, 2021) |
| " The plant extract at doses of 50, 100 and 150 mg/kg was tested for anti-inflammatory activity against carrageenan and egg albumin induced paw edema in mice and analgesic activity was appraised against acetic acid induced writhing and formalin induced paw licking in mice models." | 3.96 | Evaluation of anti-inflammatory and analgesic activities of aqueous methanolic extract of Ranunculus muricatus in albino mice. ( Alamgeer, -; Asif, H; Hasan, UH; Irfan, HM; Nasreen, P; Sharif, A; Uttra, AM; Younis, W, 2020) |
| "Coconut water vinegar has helped to attenuate acetaminophen-induced liver damage by restoring antioxidant activity and suppression of inflammation." | 3.88 | Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice. ( Alitheen, NB; Beh, BK; Ho, WY; Ky, H; Lim, KL; Long, K; Mohamad, NE; Sharifuddin, SA; Yeap, SK, 2018) |
| " were studied in the models of acute aseptic inflammation induced by carrageenan, histamine, and serotonin and acetic acid-induced painful chemical stimulation." | 3.85 | Anti-Inflammatory and Analgesic Activities of the Complex of Flavonoids from Lychnis chalcedonica L. ( Afanas'eva, OG; Aksinenko, SG; Amosova, EN; Krylova, SG; Lopatina, KA; Nesterova, YV; Povet'eva, TN; Rybalkina, OY; Suslov, NI; Zibareva, LN; Zueva, EP, 2017) |
| " Methods The anti-nociceptive potentials of the extracts were studied using the acetic acid-induced writhing test in mice and the antipyretic activity was investigated using yeast-induced pyrexia in rats." | 3.85 | In vivo analgesic, antipyretic and anti-inflammatory potential of leaf extracts and fractions of Eria javanica. ( Ahmed, F; Bhuiya, NM; Hasan, M; Kabir, MS; Mahmud, ZA; Qais, N; Uddin, MM, 2017) |
| "05) suppressed topical ear edema, systemic paw edema, global edematous response to formaldehyde arthritis and granuloma tissue growth." | 3.83 | Extracts of Leptadenia hastata Leaf, a Famine Food and Traditional Remedy for Furuncles, Suppress Inflammation in Murine Models. ( Akah, PA; Ezea, SC; Ezike, AC; Okoli, CO; Ufere, IK, 2016) |
| "The probable mechanisms of action of kolaviron were assessed by using naloxone, prazosin, and atropine to investigate the involvement of adrenergic, opioidergic, and cholinergic systems, respectively, using tail flick, the acetic acid-induced writhing, formalin-induced paw licking, and carrageenan-induced paw edema models." | 3.83 | Antinociceptive and anti-inflammatory potentials of kolaviron: mechanisms of action. ( Onasanwo, SA; Rotu, RA, 2016) |
| "Kolaviron possesses antinociceptive and anti-inflammatory activity, both centrally and peripherally, which justifies its folkloric use to relieve pain and inflammation." | 3.83 | Antinociceptive and anti-inflammatory potentials of kolaviron: mechanisms of action. ( Onasanwo, SA; Rotu, RA, 2016) |
| " The analgesic, anti-inflammatory and anti-platelet activities were assessed using acetic acid and formalin-induced nociception in mice, carrageenan-induced rat paw edema and arachidonic acid-induced platelets aggregation tests." | 3.83 | Analgesic, anti-inflammatory and anti-platelet activities of Buddleja crispa. ( Bukhari, IA; Gilani, AH; Meo, SA; Saeed, A, 2016) |
| "The combination of pomegranate seed oil and ketoprofen in nanoemulsions aiming to improve the antinociceptive effect was evaluated according to the writhing test and Complete Freud's Adjuvant induced paw inflammation in mice." | 3.83 | Pomegranate seed oil nanoemulsions improve the photostability and in vivo antinociceptive effect of a non-steroidal anti-inflammatory drug. ( Barbieri, AV; Beck, RCR; Cervi, VF; Cruz, L; Ferreira, LM; Gehrcke, M; Nogueira, CW; Sari, MHM; Zborowski, VA, 2016) |
| " At same doses, SP-Ul was tested on Wistar rats on paw edema elicited by different irritants (carrageenan, dextran, bradykinin, histamine or serotonin)." | 3.83 | Analgesic and anti-inflammatory actions on bradykinin route of a polysulfated fraction from alga Ulva lactuca. ( Benevides, NM; Bezerra, MM; Chaves, HV; de Araújo, IW; de Sousa Oliveira Vanderlei, E; Maciel, GF; Pereira, KM; Quinderé, AL; Ribeiro, KA; Ribeiro, NA; Rodrigues, JA; Silva, JF, 2016) |
| " In this study, we evaluated the ability of goat whey to prevent intestinal inflammation in the experimental model of acetic acid-induced rats and compared it to sulfasalazine." | 3.83 | Goat whey ameliorates intestinal inflammation on acetic acid-induced colitis in rats. ( Antonino de Assis, PO; Antunes de Araújo, A; Araújo, DFS; Formiga de Sousa, YR; Gálvez, J; Guerra, GCB; Júnior, RFA; Nunes de Medeiros, A; Pintado, MME; Queiroga, RCRDE, 2016) |
| " Additionally, we evaluated the analgesic effect on the acetic acid-induced writhing response and the inhibitory activity on xylene-induced ear edema in mice." | 3.81 | Anti-inflammatory and analgesic effects of pyeongwisan on LPS-stimulated murine macrophages and mouse models of acetic acid-induced writhing response and xylene-induced ear edema. ( Cho, WK; Gu, MJ; Ha, JH; Jeong, YH; Ma, JY; Oh, YC, 2015) |
| " Then, the pharmacological activities of FJHQT extract with respect to clinical use was investigated with acetic acid-induced writhing response, formalin-induced licking response and carrageenan-induced paw edema." | 3.81 | Anti-nociceptive, anti-inflammatory and toxicological evaluation of Fang-Ji-Huang-Qi-Tang in rodents. ( Chang, CW; Lin, YC; Wu, CR, 2015) |
| "Yeast induced pyrexia, Paw edema, acetic acid-induced writhing and hot plate test were carried out in vivo." | 3.81 | Antipyretic, anti-inflammatory and analgesic activity of Acacia hydaspica R. Parker and its phytochemical analysis. ( Afsar, T; Khan, MR; Mirza, B; Razak, S; Ullah, S, 2015) |
| "Acetic acid writhing and tail flick tests were used to evaluate the analgesic activity, and yeast-induced fever in mice was used to evaluate the antipyretic activity of the solvent fractions." | 3.81 | In Vivo Analgesic and Antipyretic Activities of N-Butanol and Water Fractions of Ocimum Suave Aqueous Leaves Extract in Mice. ( Makonnen, E; Tesema, S, 2015) |
| " Xylene-induced ear edema, carrageenan-induced paw edema and acetic acid-induced vascular permeability test were used to investigate the anti-inflammatory activities of GL in mice." | 3.81 | Observing Anti-inflammatory and Anti-nociceptive Activities of Glycyrrhizin Through Regulating COX-2 and Pro-inflammatory Cytokines Expressions in Mice. ( Li, YX; Ma, L; Niu, Y; Niu, YT; Shi, GJ; Sun, T; Wang, HL; Wu, J; Yu, JQ; Zheng, J, 2015) |
| " Additionally, anti-inflammatory function of gelsolin (8 mg/mouse) compared with anti-inflammatory drug diclofenac sodium (10 mg/kg)] was confirmed in the carrageenan injection induced paw edema where latter was measured by vernier caliper and fluorescent tomography imaging." | 3.81 | Analgesic and Anti-Inflammatory Properties of Gelsolin in Acetic Acid Induced Writhing, Tail Immersion and Carrageenan Induced Paw Edema in Mice. ( Chopra, BS; Choudhary, V; Garg, R; Gupta, AK; Khatri, N; Parasar, D; Sagar, A, 2015) |
| " & Naudin (Ss-EtOH) in the experimental models of edema induced by carrageenan, dextran, or histamin and nociception induced by chemical stimuli, such as acetic acid, formalin, capsaicin, or glutamate." | 3.80 | Anti-inflammatory and antinociceptive effects of Sterculia striata A. St.-Hil. & Naudin (Malvaceae) in rodents. ( Almeida, FR; Amaral, MP; Chaves, MH; Costa, DA; Figueiredo, KA; Júnior, FB; Oliveira, FA; Oliveira, IS; Oliveira, RC; Silva, FV, 2014) |
| " Acetic acid-induced writhing, paw licking induced by formalin, hot plate, and carrageenan-induced paw edema tests were used to investigate the anti-inflammatory and antinociceptive activities of the xanthone compound." | 3.80 | Analgesic and anti-inflammatory activities of the 2,8-dihydroxy-1,6-dimethoxyxanthone from Haploclathra paniculata (Mart) Benth (Guttiferae). ( Dias Silva, MJ; Dias, DF; Doriguetto, AC; dos Santos, MH; Giusti-Paiva, A; Gontijo, VS; Moreira, ME; Nagem, TJ; Pereira, RG; Veloso, MP, 2014) |
| " The bioactivity of this compound was assessed using carrageenan-induced paw oedema in rats and carrageenan-induced pulmonary oedema in mice for the anti-inflammatory activity, while acetic acid-induced writhing test in mice and zymosan-induced fever in rats were used for analgesic test." | 3.80 | Studies on the anti-inflammatory, analgesic and antipyrexic activities of betulinic acid derived from Tetracera potatoria. ( Oridupa, OA; Oyebanji, BO; Saba, AB, 2014) |
| " The aim of the present study was to investigate the potential protective effect of l-arginine (Arg; nitric oxide precursor) and aminoguanidine (inducible nitric oxide synthase inhibitor) against acetic acid (AA)-induced colitis in rats, and the potential role of NF-κB." | 3.80 | L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65. ( Farghaly, HS; Thabit, RH, 2014) |
| "Intra-gastric administration of AGB (75, 150, and 300 mg/kg) showed a dose-dependent antinociceptive effect in intraperitoneal acetic acid (writhing), thermal nociception in CD1 mice, and subplantar formalin models, as well as anti-inflammatory effect in carrageenan- induced paw edema in Wistar rats." | 3.80 | Antinociceptive and anti-inflammatory activities of Geranium bellum and its isolated compounds. ( Altamirano-Báez, DA; Ángeles, LJ; Bautista-Ávila, M; Cariño-Cortés, R; De la O Arciniega, M; Gayosso de Lucio, JA; Ortiz, MI; Velázquez-González, C, 2014) |
| " bellum (AGB) extract and the isolated compounds were assessed using experimental pain models, including thermal nociception like hot plate test, and chemical nociception induced by intraperitoneal acetic acid or subplantar formalin injection in vivo." | 3.80 | Antinociceptive and anti-inflammatory activities of Geranium bellum and its isolated compounds. ( Altamirano-Báez, DA; Ángeles, LJ; Bautista-Ávila, M; Cariño-Cortés, R; De la O Arciniega, M; Gayosso de Lucio, JA; Ortiz, MI; Velázquez-González, C, 2014) |
| "AEBO produced a significant inhibition of histamine-induced paw edema starting at 60 min time point, with maximal percentage of inhibition (60." | 3.79 | Chemical constituents and antihistamine activity of Bixa orellana leaf extract. ( Ahmad, Z; Ee Cheng Lian, G; Kadir, AA; Somchit, MN; Yong, YK; Zakaria, ZA, 2013) |
| " Further, an acetic acid-induced writhing test and tail immersion test were employed to screen for analgesic effects, yeast-induced pyrexia was used to test for antipyretic effects, and gastric ulceration was used to evaluate ulcerogenic effects." | 3.79 | Dietary component p-coumaric acid suppresses monosodium urate crystal-induced inflammation in rats. ( Pragasam, SJ; Rasool, M, 2013) |
| " Opioid coadministration had a synergistic effect in the acute tonic pain (acetic acid writhing test), acute phasic pain (tail flick test) and inflammatory pain (orofacial formalin test)." | 3.79 | Systemic synergism between codeine and morphine in three pain models in mice. ( Miranda, HF; Noriega, V; Prieto, JC; Sierralta, F; Zepeda, RJ, 2013) |
| " The antinociceptive study of DV was performed using models of acetic acid-induced writhing and formalin-induced pain in mice." | 3.79 | Bioassay-guided evaluation of Dioscorea villosa - an acute and subchronic toxicity, antinociceptive and anti-inflammatory approach. ( Araújo, AA; Barreto, RS; de Albuquerque, RL; de Almeida, EB; Lima, AK; Lima, CM; Melo, MG; Moraes, VR; Nogueira, PC; Oliveira, DL; Oliveira, ER; Quintans-Júnior, LJ; Serafini, MR, 2013) |
| "Thirty rats were divided into five groups: a control group, an acetic acid-induced colitis group, a group treated with melatonin before colitis induction, a group treated short-term after colitis induction, and a group treated long-term after colitis induction." | 3.79 | The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat. ( Blann, A; El Sers, DA; Idriss, NK; Jaumdally, RJ; Sayyed, HG, 2013) |
| "Melatonin is effective in prevention and short-term treatment of the inflammatory process in acetic-acid induced colitis whereas the benefit of long-term treatment is unclear." | 3.79 | The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat. ( Blann, A; El Sers, DA; Idriss, NK; Jaumdally, RJ; Sayyed, HG, 2013) |
| "Melatonin may be involved in gastrointestinal tract physiology and could affect inflammation-related gastrointestinal disorders." | 3.79 | The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat. ( Blann, A; El Sers, DA; Idriss, NK; Jaumdally, RJ; Sayyed, HG, 2013) |
| " The anti-inflammatory and anti-nociceptive activities of 40% ethanolic extracts of the three plants were compared using the models of xylene-induced ear edema, formalin-induced inflammation, carrageenan-induced air pouch inflammation, acetic acid-induced writhing and formalin-induced nociception." | 3.79 | Comparison of active constituents, acute toxicity, anti-nociceptive and anti-inflammatory activities of Porana sinensis Hemsl., Erycibe obtusifolia Benth. and Erycibe schmidtii Craib. ( Chen, Z; Liao, L; Wang, Z; Wu, L; Zhang, Z, 2013) |
| " The anti-inflammatory activity was investigated using carragenin, egg-albumin induced oedema models, while acetic acid, formalin-induced paw licking and thermal-induced pain models were used to evaluate the antinociceptive property." | 3.78 | Anti-inflammatory and analgesic activities of Melanthera scandens. ( Amazu, LU; Frank, SG; Okokon, JE; Udoh, AE, 2012) |
| " The animals were randomly divided into Patrinia villosa group (PV group), dexamethasone group (DEX group), and model-control group (CON group) to perform an ear edema test, a carrageenin-induced paw edema test, a cotton pellet-induced granuloma formation test, and an acetic acid-induced writhing test." | 3.78 | The anti-inflammatory and anti-nociceptive activities of Patrinia villosa and its mechanism on the proinflammatory cytokines of rats with pelvic inflammation. ( Huang, Y; Jin, Y; Xia, YX; Xu, ST; Zheng, Y; Zhu, HB, 2012) |
| "The anti-inflammatory property of CPZ on acute inflammation was evaluated by inflammatory models of dimethylbenzene (DMB)-induced ear vasodilatation and acetic acid-induced capillary permeability enhancement in mice, as well as the carrageenan-induced paw edema rat model, in which inflammation-related cytokine including prostaglandin E(2) (PGE(2)), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and nitric oxide (NO) in the edematous paw tissue were determined by enzyme linked immunosorbent assay (ELISA)." | 3.78 | Experimental study on anti-inflammatory activity of a TCM recipe consisting of the supercritical fluid CO2 extract of Chrysanthemum indicum, Patchouli Oil and Zedoary Turmeric Oil in vivo. ( Lai, P; Lai, XP; Liang, HC; Qin, Z; Su, JY; Su, ZR; Tan, LR; Ye, MR, 2012) |
| " All the compounds were assessed for analgesic and antiinflammatory activities using an acetic acid-induced writhing model, a hot-plate test, a carrageenan-induced paw oedema model, a cotton-pellet oedema model and in vitro lipoxygenase inhibitory assay." | 3.78 | Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc. ( Adhikari, A; Gul, F; Kaleem, WA; Khan, A; Khan, I; Khan, IA; Khan, N; Nisar, M; Qayum, M; Shah, MR; Zia-Ul-Haq, M, 2012) |
| "The results suggest that the methanolic extract of Cyathula prostrata possesses anti-inflammatory and analgesic activities and this authenticates the use of the plant in the traditional treatment of ailments associated with inflammation and pain." | 3.78 | Antiinflammatory, analgesic and antioxidant activities of Cyathula prostrata (Linn.) Blume (Amaranthaceae). ( Ibrahim, B; Sowemimo, A; Van de Venter, M; van Rooyen, A, 2012) |
| " Carrageenan induced paw edema model was used for anti-inflammatory and acetic acid induced model used for analgesic activity." | 3.78 | Anti-inflammatory and analgesic potential of a novel steroidal derivative from Bryophyllum pinnatum. ( Afzal, M; Afzal, O; Alam, J; Anwar, F; Gupta, G; Gupta, R; Hakeem, KR; Kazmi, I; Pravez, M; Rahman, M, 2012) |
| " Nevertheless, the anti-inflammatory activity was tested in carrageenan induced paw edema and histamine induced inflammatory tests." | 3.78 | Antipyretic, analgesic and anti-inflammatory activity of Viola betonicifolia whole plant. ( Khan, H; Muhammad, N; Saeed, M, 2012) |
| " Similarly carrageenan and histamine induces inflammation was significantly antagonized by VBME, 66." | 3.78 | Antipyretic, analgesic and anti-inflammatory activity of Viola betonicifolia whole plant. ( Khan, H; Muhammad, N; Saeed, M, 2012) |
| " Analgesic activity was evaluated using the acetic acid-induced writhing and hot plate tests in mice while carrageenan induced paw oedema test was used to investigate the anti-inflammatory actions of the fractions obtained." | 3.78 | Bioactivity guided isolation of analgesic and anti-inflammatory constituents of Cnestis ferruginea Vahl ex DC (Connaraceae) root. ( Adeyemi, OO; Agbaje, OE; Ishola, IO; Narender, T; Shukla, R, 2012) |
| "05) dose dependent inhibition of pain response elicited by acetic acid and increased nociceptive reaction latency in hot plate test." | 3.78 | Bioactivity guided isolation of analgesic and anti-inflammatory constituents of Cnestis ferruginea Vahl ex DC (Connaraceae) root. ( Adeyemi, OO; Agbaje, OE; Ishola, IO; Narender, T; Shukla, R, 2012) |
| " EO(MeOH) was evaluated for its analgesic activity in acetic acid-induced writhing response and formalin test, and anti-inflammatory effect was examined by λ-carrageenan-induced paw edema assay." | 3.78 | Analgesic and anti-inflammatory activities of the methanol extract of Elaeagnus oldhamii Maxim. in mice. ( Chang, YS; Ho, YL; Lai, SC; Liao, CR; Peng, WH, 2012) |
| "The antinociceptive and antiinflammatory activities of MEA were evaluated using the writhing, formalin, and tail-flick tests, carrageenan-induced paw edema and arachidonic acid-induced ear edema." | 3.77 | Antinociceptive and antiinflammatory activities of Adiantum latifolium Lam.: evidence for a role of IL-1β inhibition. ( Barros, TA; Lucchese, AM; Nogueira, TM; Nonato, FR; Oliveira, CE; Santos, RR; Soares, MB; Villarreal, CF, 2011) |
| " In addition, MEA (100 and 200mg/kg/IP) inhibited important events related to the inflammatory response induced by carrageenan or arachidonic acid, namely local edema and increase in tissue interleukin-1β levels." | 3.77 | Antinociceptive and antiinflammatory activities of Adiantum latifolium Lam.: evidence for a role of IL-1β inhibition. ( Barros, TA; Lucchese, AM; Nogueira, TM; Nonato, FR; Oliveira, CE; Santos, RR; Soares, MB; Villarreal, CF, 2011) |
| " 2) Mice with xylene-induced acute exudative edema and acetic acid-induced writhing." | 3.77 | Evidence for the complementary and synergistic effects of the three-alkaloid combination regimen containing berberine, hypaconitine and skimmianine on the ulcerative colitis rats induced by trinitrobenzene-sulfonic acid. ( Guo, Z; Li, C; Li, Q; Li, Y; Liu, L; Long, Y; Mei, Q; Niu, Y; Sun, Y; Wang, Y; Wu, H; Zhang, M, 2011) |
| " Firstly, the anti-inflammatory and analgesic effects of the FEO were studied by xylene-induced ear edema, adjuvant-induced joint inflammation law in rats, acetic acid-induced writhing and hot-plate tests in mice." | 3.77 | The studies of anti-inflammatory and analgesic activities and pharmacokinetics of Oxytropis falcate Bunge extraction after transdermal administration in rats. ( Cai, BC; Chen, HX; Chen, J; Chen, ZP; Liu, D; Lu, TL; Qu, MM; Xiao, YY, 2011) |
| " While the analgesic activity was examined against thermally and chemically induced nociceptive pain in mice, using the acetic acid and hot-plate test methods." | 3.77 | Anti-inflammatory and analgesic activity of different extracts of Commiphora myrrha. ( Duan, JA; Hua, YQ; Qian, DW; Su, S; Tang, YP; Wang, T; Yu, L; Zhou, W, 2011) |
| "Salicylaldehyde 2-chlorobenzoyl hydrazone (H(2)LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H(2)LASSBio-1064) and their complexes [Zn(LASSBio-466)H(2)O](2) (1) and [Zn(HLASSBio-1064)Cl](2) (2) were evaluated in animal models of peripheral and central nociception, and acute inflammation." | 3.77 | Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (H(2)LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H(2)LASSBio-1064) and their zinc(II) complexes. ( Alexandre-Moreira, MS; Alves, MA; Barreiro, EJ; Beraldo, H; Castellano, EE; Júnior, WB; Lima, LM; Parrilha, GL; Perez-Rebolledo, A; Piro, OE, 2011) |
| " Three more models, acetic acid-induced mouse vascular permeation, cotton pellet-induced rat granuloma, and carrageenan-induced rat hind paw edema were also employed to verify the anti-inflammatory effect of the identified fraction." | 3.77 | Anti-inflammatory activities and mechanisms of action of the petroleum ether fraction of Rosa multiflora Thunb. hips. ( Cao, X; Chan, CO; Chen, S; Guo, D; Guo, Y; Mok, DK; Xu, L; Ye, Y; Yu, Z, 2011) |
| " The analgesic effect was studied using acetic acid-induced abdominal constriction and hot plate test in mice, while the anti-inflammatory effect was investigated using carrageenan induced paw oedema in rats." | 3.77 | Evaluation of analgesic and anti-inflammatory effects of ethanol extract of Ficus iteophylla leaves in rodents. ( Abdulkadir, MF; Abdullahi, MI; Abdulmalik, IA; Musa, AM; Sule, MI; Yaro, AH; Yusuf, H, 2011) |
| "This study examined the analgesic and anti-inflammatory actions of cis-mulberroside A isolated from Ramulus mori in several models of inflammatory pain in mice." | 3.76 | Anti-inflammatory and analgesic properties of cis-mulberroside A from Ramulus mori. ( Shi, L; Zhang, Z, 2010) |
| " For the anti-inflammatory activity, the carrageenan-induced hind paw edema and acetic acid-induced increased capillary permeability models were used, whereas for the antinociceptive activity, the p-benzoquinone-induced writhing and hot plate tests in mice were used." | 3.76 | Assessment of anti-inflammatory and antinociceptive activities of Olea europaea L. ( Akkol, EK; Baykal, T; Süntar, IP, 2010) |
| " Antipyretic (Baker's yeast-induced fever test), analgesic (acetic acid-induced writhing, tail immersion assays), anti-inflammatory (carrageenan-induced paw edema) and in vitro antioxidant (DPPH radical, superoxide radical scavenging) activities of evodione and leptonol were tested." | 3.76 | Antipyretic, analgesic, anti-inflammatory and antioxidant activities of two major chromenes from Melicope lunu-ankenda. ( Baby, S; Chandrasekhar, A; Chandrika, SP; Johnson, AJ; Kumar R, A; Rasheed, SA; Subramoniam, A, 2010) |
| " The results showed that PL significantly and dose-dependently suppressed the paw edema of rats induced by carrageenan and various proinflammatory mediators, including histamine, serotonin, bradykinin, and prostaglandin E(2)." | 3.76 | Anti-inflammatory and analgesic effect of plumbagin through inhibition of nuclear factor-κB activation. ( Ge, L; Liu, L; Liu, Y; Luo, P; Wong, YF; Zhang, ZF; Zhou, H, 2010) |
| "01% acetic acid were used to induce mild localised inflammation within bronchopulmonary segments." | 3.76 | Experimental mild pulmonary inflammation promotes the development of exercise-induced pulmonary haemorrhage. ( McKane, SA; Slocombe, RF, 2010) |
| "It has been shown that the ethanol and aqueous extracts significantly increased the hot-plate pain threshold and reduced acetic acid-induced writhing response in mice." | 3.75 | Anti-inflammatory and analgesic effects of ethanol and aqueous extracts of Pterocephalus hookeri (C.B. Clarke) Höeck. ( Du, GH; Fang, WS; Hu, JJ; Lin, JW; Zhang, L, 2009) |
| " Pretreatment with a single dose of sophocarpine also produced significant dose-dependent anti-inflammatory effects on carrageenan-induced rat hind paw edema (15 and 30 mg/kg), xylene-induced mouse ear edema (20 and 40 mg/kg) and acetic acid-induced mouse vascular permeation (20 and 40 mg/kg)." | 3.75 | Anti-nociceptive and anti-inflammatory activity of sophocarpine. ( Fu, C; Gao, Y; Li, B; Li, C; Li, G; Li, M; Zhu, X, 2009) |
| "Pretreatment with a single dose of sophocarpine (20 and 40 mg/kg) produced dose-dependent anti-nociceptive effects in thermally and chemically induced mouse pain models." | 3.75 | Anti-nociceptive and anti-inflammatory activity of sophocarpine. ( Fu, C; Gao, Y; Li, B; Li, C; Li, G; Li, M; Zhu, X, 2009) |
| " Thalidomide is effective in reducing the extent of arthritis as well as reducing the seizure scoring and increasing seizure onset in the adjuvant arthritis group." | 3.74 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| " The glucan was tested for its effects on the acetic acid-induced writhing reaction in mice, a typical model for quantifying inflammatory pain." | 3.74 | Anti-inflammatory and analgesic properties in a rodent model of a (1-->3),(1-->6)-linked beta-glucan isolated from Pleurotus pulmonarius. ( Baggio, CH; Carbonero, ER; Freitas, CS; Gorin, PA; Iacomini, M; Marcon, R; Olsen, LM; Santos, AR; Smiderle, FR, 2008) |
| "Effects of complex and individual bioactive substances extracted from tall delphinium on acute inflammation induced by carrageenin, acetic acid, serotonin, and histamine were studied." | 3.74 | Effects of bioactive substances from tall delphinium on the development of acute inflammation of different genesis. ( Andreeva, TI; Nagornyak, YG; Nesterova, YV; Poveteva, TN; Suslov, NI, 2008) |
| ", synergistic) in preclinical models of visceral and inflammatory pain, specifically acetic acid-induced writhing in mice and carrageenan-induced thermal hyperalgesia and mechanical allodynia in rats." | 3.74 | Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents. ( Jones, CK; Peters, SC; Shannon, HE, 2007) |
| " Isobolographic analysis of the effects of duloxetine in combination with ibuprofen revealed a significant synergistic (greater than additive) interaction between duloxetine and ibuprofen both for reducing acetic acid-induced writhing and carrageenan-induced thermal hyperalgesia, but were additive for reversing mechanical allodynia." | 3.74 | Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents. ( Jones, CK; Peters, SC; Shannon, HE, 2007) |
| "Our data indicate that duloxetine and ibuprofen have synergistic efficacy in a visceral and an inflammatory pain model in rodents, and suggest that duloxetine and ibuprofen in combination may provide a useful approach to the clinical treatment of persistent pain, particularly inflammation-related pain." | 3.74 | Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents. ( Jones, CK; Peters, SC; Shannon, HE, 2007) |
| "In the present study, we have investigated the analgesic effect of the aqueous extract of the root of Glycine tomentella (AGT) using models of acetic acid-induced writhing response and formalin test, the anti-inflammatory effect of AGT using model of lambda-carrageenan-induced paw edema." | 3.74 | Analgesic and anti-inflammatory activities of aqueous extract from Glycine tomentella root in mice. ( Huang, HW; Hung, YC; Ko, YZ; Lin, YC; Lu, TC; Peng, WH, 2007) |
| " indica dry extract (100, 200 and 400 mg kg-1) exhibited dose dependent and significant anti-inflammatory activity in acute (carrageenean and histamine induced hind paw oedema, p < 0." | 3.74 | Anti-inflammatory and anti-nociceptive activities of Fumaria indica whole plant extract in experimental animals. ( Gupta, PK; Rao, CV; Verma, AR; Vijayakumar, M, 2007) |
| "Infusions of Indian black tea (BTI), when administered orally, produced significant inhibition of rat paw oedema, induced with carrageenin (pre and post treatment) and arachidonic acid." | 3.74 | Pharmacological studies on Indian black tea (leaf variety) in acute and chronic inflammatory conditions. ( Adhikari, D; Karmakar, S; Kumar, KT; Pal, S; Roy, DK; Samanta, SK; Sen, T, 2008) |
| " The acetic acid-induced writhing test, tail flick test and the tetradecanoylphorbol acetate (TPA)-induced ear inflammation model in mice were used to determine these effects." | 3.73 | Analgesic and topical anti-inflammatory activity of Hypericum canariense L. and Hypericum glandulosum Ait. ( Bonkanka, CX; Hernández-Pérez, M; Rabanal, RM; Sánchez-Mateo, CC, 2005) |
| "Colitis was induced by intracolonic administration of acetic acid (5%) in Sprague-Dawley rats (200-250 g)." | 3.73 | Oxytocin ameliorates oxidative colonic inflammation by a neutrophil-dependent mechanism. ( Ercan, F; Gedik, N; Işeri, SO; Sağlam, B; Sener, G; Yeğen, BC, 2005) |
| "All inflammation parameters were increased by acetic acid-induced colitis or ethanol-induced gastric ulcer compared with the control group." | 3.73 | Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes. ( Cevík, H; Ercan, F; Erkanli, G; Işman, CA; Yeğen, BC, 2005) |
| " The oral administration of aspartame (2-16mg/kg, po) significantly increased the pain threshold against acetic acid-induced writhes in mice." | 3.73 | Possible analgesic and anti-inflammatory interactions of aspartame with opioids and NSAIDs. ( Jain, NK; Kulkarni, SK; Sharma, S, 2005) |
| " It also inhibited carrageenan-induced acute edema and acetic acid-induced writhing response." | 3.73 | Prevention of arthritic inflammation using an oriental herbal combination BDX-1 isolated from Achyranthes bidentata and Atractylodes japonica. ( Han, SB; Kang, JS; Kim, HM; Lee, CW; Lee, JH; Lee, K; Lee, KH; Park, SK; Yoon, WK; Yoon, YD, 2005) |
| " Gaultherin, 2-[(6-O-beta-D-Xylopyranosyl-beta-D-glucopyranosyl)oxy] benzoic acid methyl ester, a natural salicylate derivative extracted from Gaultheria yunnanensis, has been shown to have analgesic and anti-inflammatory effects and lack gastric ulcerogenic effect compared to aspirin in our primary study." | 3.73 | Gaultherin, a natural salicylate derivative from Gaultheria yunnanensis: towards a better non-steroidal anti-inflammatory drug. ( Ding, Y; Du, GH; He, XL; Zhang, B, 2006) |
| " The antiinflammatory property of the aqueous leaf extract was investigated in rats, using fresh egg albumin-induced pedal (paw) edema, while the analgesic effect of the plant extract was evaluated by the "hot-plate" and "acetic acid" test models of pain in mice." | 3.73 | Antiinflammatory and analgesic effects of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract in rats and mice. ( Ojewole, JA, 2006) |
| " Dose dependent percent inhibition of granuloma formation, exudate volume, total leukocyte count was observed in 4e (25, 50 and 100 mg/kg) and celecoxib (CAS 169590-42-5; 5 mg/kg) treated groups in the cotton pellet granuloma and granuloma pouch technique, respectively, in rats." | 3.73 | Evaluation of anti-inflammatory and analgesic activity of a new class of biphenyl analogs in animal models of inflammation. ( Bodhankar, SL; Kulkarni, VM; Rathi, BS; Wagh, NK, 2006) |
| " To investigate the anti-inflammatory and anti-oxidant activity of these compounds, their effects on carrageenan-induced paw edema, arachidonic acid (AA)-induced ear edema and analgesic activity in acetic acid (HAc)-induced writhing response were carried out in vivo; cyclooxygenase (COX) activity, reactive oxygen species (ROS) generation in rat basophilic leukemia (RBL 2H3) cells and 1,1-diphenyl-2-picryl-hydroazyl (DPPH) scavenging activity were determined in vitro." | 3.73 | Anti-inflammatory action of phenolic compounds from Gastrodia elata root. ( Jang, YW; Kang, HS; Kim, CJ; Lee, JY; Moon, H; Sim, SS, 2006) |
| "The effect of methanolic extract of Asparagus pubescens was investigated on chemical, thermal-induced pain as well as fresh egg albumin-induced inflammation and pentylenetetrazol (PTZ)-induced convulsion in rodents." | 3.72 | Anti-nociceptive and anti-inflammatory effects of methanolic extract of Asparagus pubescens root in rodents. ( Nwafor, PA; Okwuasaba, FK, 2003) |
| " The effect on acute inflammation was studied using vascular permeability increased by acetic acid and xylene-induced ear oedema in mice." | 3.72 | Antinociceptive, antiinflammatory and acute toxicity effects of Salvia leriifolia Benth seed extract in mice and rats. ( Arash, AR; Haddadkhodaparast, MH; Hosseinzadeh, H, 2003) |
| "We previously discovered that a 4-wk course of indomethacin delivered to rats with acetic acid ulcers resulted in production of "unhealed gastric ulcers" that persisted for up to 12 wks after treatment cessation." | 3.72 | Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats. ( Amagase, K; Okabe, S; Tsukimi, Y; Yokota, M, 2003) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid in male Sprague-Dawley rats." | 3.72 | Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis. ( Kang, JW; Kim, HJ; Kim, TW; La, JH; Sung, TS; Yang, IS, 2003) |
| "The present study was designed to compare the effect of leptin on acute colonic inflammation with that of acute stress exposure, which acts via the hypothalamic-pituitary-adrenal (HPA) axis." | 3.72 | The anti-inflammatory effect of leptin on experimental colitis: involvement of endogenous glucocorticoids. ( Bozkurt, A; Cakir, B; Ercan, F; Yeğen, BC, 2004) |
| " Pain nociception, as assessed by the acetic acid writhing response, was reduced significantly in KO mice relative to WT mice." | 3.72 | Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1. ( Akira, S; Azuma, Y; Hirasawa, N; Ishii, T; Ishikawa, Y; Kamei, D; Kawaguchi, H; Kudo, I; Mikami-Nakanishi, M; Murakami, M; Nakatani, Y; Oh-Ishi, S; Ohuchi, K; Takegoshi, Y; Uematsu, S; Yamakawa, K; Yasui, H, 2004) |
| "The antihyperalgesic effect of pentoxifylline was investigated in three experimental pain models." | 3.72 | Antihyperalgesic effect of pentoxifylline on experimental inflammatory pain. ( Benevides, VM; Brito, GA; Cunha, FQ; da Rocha, FA; Ferreira, SH; Poole, S; Ribeiro, RA; Sachs, D; Vale, ML, 2004) |
| "The methanol extract of the florets of Tagetes patula (MEFTP) inhibited acute and chronic inflammation in mice and rats." | 3.71 | Effect of methanol extract from flower petals of Tagetes patula L. on acute and chronic inflammation model. ( Evans, FJ; Kasahara, Y; Khan, MT; Kitanaka, S; Yasukawa, K, 2002) |
| " mascaensis (Lamiaceae), and chloroform and aqueous fractions were evaluated in mice using paw and ear oedema induced by carrageenan and 12-o-tetradecanoyl-phorbol-acetate (TPA), respectively, as inflammation models, the writhing test induced by acetic acid for evaluating analgesic activity and the disk-diffusion method for testing antimicrobial actions." | 3.71 | Analgesic and antiinflammatory properties of Sideritis lotsyi var. Mascaensis. ( Hernández-Pérez, M; Rabanal Gallego, RM, 2002) |
| " The effect of the extracts against acute inflammation was studied by acetic acid increased vascular permeability and xylene-induced ear edema in mice." | 3.71 | Antinociceptive, anti-inflammatory and acute toxicity effects of Zhumeria majdae extracts in mice and rats. ( Fadishei, M; Hosseinzadeh, H; Mahmoudi, M; Ramezani, M, 2002) |
| " That is, it exhibited in vivo anti-inflammatory activity in several tested inflammatory reactions including 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse ear edema, carrageenan-induced rat paw edema, and acetic acid-induced mouse writhing." | 3.70 | Suppression of inflammatory responses by surfactin, a selective inhibitor of platelet cytosolic phospholipase A2. ( Jung, JK; Jung, SY; Kim, DK; Kim, K; Lee, CH; Lee, DK; Park, JK, 1998) |
| "The present study shows that meloxicam dose-dependently exhibited systemic antinociceptive action when assessed against neurogenic and inflammatory pain caused by acetic acid, formalin and capsaicin models." | 3.70 | Antinociceptive effect of meloxicam, in neurogenic and inflammatory nociceptive models in mice. ( De Freitas, GA; Santos, AR; Vedana, EM, 1998) |
| " Tests of other neurogenic inflammatory stimuli in NK1 -/- mice revealed impaired behavioural responses to cyclophosphamide cystitis and no acute reflex responses or primary hyperalgesia to intracolonic acetic acid." | 3.70 | Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene. ( Cervero, F; De Felipe, C; Hunt, SP; Laird, JM; Olivar, T; Roza, C, 2000) |
| "The authors investigated the anti-inflammatory actions of ketoprofen using a battery of tests: in the rat paw oedema test induced by five different inciters, in the capillary permeability test, and in measuring the interleukin-8 (IL-8) production and superoxide dismutase (SOD) activity." | 3.69 | The anti-inflammatory effects of ketoprofen in animal experiments. ( Honda, Y; Koikei, Y; Mineshita, S; Nomura, Y; Shiba, K; Toyoshima, A; Wang, LM; Wang, XX; Yamamoto, T; Yang, L, 1997) |
| "Colitis was evoked by a single transrectal injection of 1 ml of 4 % acetic acid." | 1.91 | Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia activity. ( Ahmed, KA; Elbaz, EM; Essam, RM; Safwat, MH, 2023) |
| "Ulcerative colitis is a chronic inflammation of the colon." | 1.91 | Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue. ( Amini-Khoei, H; AnjomShoa, M; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2023) |
| "To induce ulcerative colitis, animals received 0." | 1.91 | Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue. ( Amini-Khoei, H; AnjomShoa, M; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2023) |
| "Oral ulcer is a frequent condition that commonly affects the tongue and in which 75% of the patients experience pain, and 25% report taste changes." | 1.91 | Thymus satureioides Coss. combats oral ulcer via inhibition of inflammation, proteolysis, and apoptosis. ( Abdelfattah, MAO; Elbatreek, MH; Fathi, AM; Mahdi, I; Mahmoud, MF; Sobeh, M, 2023) |
| "All juglone-treated groups reduced the NF-κB levels compared to the control group (p < 0." | 1.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Juglone is a phenolic bioactive compound with antimicrobial, antitumour, antioxidant, and anti-inflammatory characteristics." | 1.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Juglone was extracted from Pterocarya fraxinifolia via maceration method." | 1.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Colitis was induced in 36 male Wistar rats (n = 6), except in the sham group, 1 ml of acetic acid 4% was administered intrarectally." | 1.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Ulcerative colitis is a chronic inflammatory disease, profoundly affecting the patient's quality of life and is associated with various complications." | 1.72 | Linagliptin ameliorates acetic acid-induced colitis via modulating AMPK/SIRT1/PGC-1α and JAK2/STAT3 signaling pathway in rats. ( El-Bahy, AAZ; El-Ghannam, MS; El-Yamany, MF; Nassar, NN; Saad, MA, 2022) |
| "Extensive evidence suggests that gut microbiota may interact with the kidneys and play central roles in the pathogenesis of disease." | 1.72 | Gut-Kidney Impairment Process of Adenine Combined with ( Deng, N; Li, X; Peng, M; Peng, X; Qiao, B; Tan, Z; Yu, R, 2022) |
| "Phloretin (50 mg/kg) was given orally for 3 days to Wistar rats after induction for the post-treatment group and 1 day before induction to the pre-treatment group." | 1.62 | Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats. ( S K, K; V S, A, 2021) |
| "Pretreatment with molsidomine significantly reduced disease activity index, colon mass index, colonic macroscopic and histological damage." | 1.62 | Molsidomine alleviates acetic acid-induced colitis in rats by reducing oxidative stress, inflammation and apoptosis. ( El-Kashef, DH; Mohamed, NI; Suddek, GM, 2021) |
| "Curcumin has proven to be beneficial in the prevention and treatment of a number of inflammatory diseases, but due its poor bioavailability, the therapeutic applications are limited." | 1.56 | Anti-Ulcerative Effect of Curcumin-Galactomannoside Complex on Acetic Acid-Induced Experimental Model by Inhibiting Inflammation and Oxidative Stress. ( Asha, S; Girishkumar, B; Grace, J; Jose, SP; Krishnakumar, IM; Ratheesh, M; Sandya, S; Sheethal, S, 2020) |
| "The pathogenesis of ulcerative colitis (UC) is related to reduced antioxidant capacity and increased inflammatory processes." | 1.56 | Anti-Ulcerative Effect of Curcumin-Galactomannoside Complex on Acetic Acid-Induced Experimental Model by Inhibiting Inflammation and Oxidative Stress. ( Asha, S; Girishkumar, B; Grace, J; Jose, SP; Krishnakumar, IM; Ratheesh, M; Sandya, S; Sheethal, S, 2020) |
| "The poncirin (30 mg/kg) treatment considerably inhibited the mechanical hyperalgesia and allodynia as well as thermal hyperalgesia and cold allodynia." | 1.51 | Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice. ( Afridi, R; Khalid, S; Khan, AU; Khan, S; Kim, YS; Rasheed, H; Shal, B; Shehzad, O; Ullah, MZ, 2019) |
| "Colitis was induced in rats by acetic acid and the rats were divided into four groups where one group served as experimental control and the other groups were treated with two doses of methanol extract of dried latex of C." | 1.51 | Protection afforded by methanol extract of Calotropis procera latex in experimental model of colitis is mediated through inhibition of oxidative stress and pro-inflammatory signaling. ( Das, P; Kumar, VL; Pandey, A; Verma, S, 2019) |
| " On the other hand, acetaminophen challenged mice treated with 14 days of coconut water vinegar were recorded with reduction of serum liver profiles, improved liver histology, restored liver antioxidant, reduction of liver inflammation and decreased level of liver cytochrome P450 2E1 in dosage dependent level." | 1.48 | Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice. ( Alitheen, NB; Beh, BK; Ho, WY; Ky, H; Lim, KL; Long, K; Mohamad, NE; Sharifuddin, SA; Yeap, SK, 2018) |
| "Most drugs used to treat pain and inflammation have potential side effects, which makes it necessary to search for new sources of bioactive molecules." | 1.48 | LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice. ( Alencar Filho, EB; Almeida, JRGDS; Barreiro, EJL; Diniz, TC; Lavor, ÉM; Lima, LM; Lima-Saraiva, SRG; Mendes, RL; Oliveira Júnior, RG; Silva, JC; Silva, MGE; Soares, JMD, 2018) |
| "Pain and inflammation are complex clinical conditions that are present in a wide variety of disorders." | 1.48 | LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice. ( Alencar Filho, EB; Almeida, JRGDS; Barreiro, EJL; Diniz, TC; Lavor, ÉM; Lima, LM; Lima-Saraiva, SRG; Mendes, RL; Oliveira Júnior, RG; Silva, JC; Silva, MGE; Soares, JMD, 2018) |
| "Ulcers were induced by serosal application of 80 % acetic acid to the stomach of rats anaesthetized with 50 mg/kg thiopentone sodium and treatment was given three times daily." | 1.46 | Effects of quinine on gastric ulcer healing in Wistar rats. ( Adeniyi, OS; Friday, ET; Makinde, OV; Olaleye, SB, 2017) |
| "Cardamonin is a natural chalcone derivative with considerable anti-inflammatory activity." | 1.46 | Protective effect of cardamonin against acetic acid-induced ulcerative colitis in rats. ( Abd Al Haleem, EN; Ali, AA; Khaleel, SA; Sallam, AS, 2017) |
| "Cardamonin has a protective effect against acetic acid-induced colitis." | 1.46 | Protective effect of cardamonin against acetic acid-induced ulcerative colitis in rats. ( Abd Al Haleem, EN; Ali, AA; Khaleel, SA; Sallam, AS, 2017) |
| "hastata leaf in the treatment of furuncles may largely derive from anti-inflammatory activities mediated through inhibition of both increase in vascular permeability and leucocyte migration, and stabilization of cell membranes." | 1.43 | Extracts of Leptadenia hastata Leaf, a Famine Food and Traditional Remedy for Furuncles, Suppress Inflammation in Murine Models. ( Akah, PA; Ezea, SC; Ezike, AC; Okoli, CO; Ufere, IK, 2016) |
| " Furthermore, time- and dose-response curves were obtained to determine the antinociceptive effect of the formulations." | 1.43 | Pomegranate seed oil nanoemulsions improve the photostability and in vivo antinociceptive effect of a non-steroidal anti-inflammatory drug. ( Barbieri, AV; Beck, RCR; Cervi, VF; Cruz, L; Ferreira, LM; Gehrcke, M; Nogueira, CW; Sari, MHM; Zborowski, VA, 2016) |
| " tragacantha exhibited anti-inflammatory and analgesic properties and they are also safe for medicinal use." | 1.43 | Phytochemical screening, safety evaluation, anti-inflammatory and analgesic studies of the leaf extracts of Sterculia tragacantha. ( Abatan, MO; Adedapo, AA; Mogbojuri, OM, 2016) |
| "In the HFHC model of NAFLD, manipulation of dietary AGEs modulates liver injury, inflammation, and liver fibrosis via a RAGE dependent pathway." | 1.43 | Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease. ( Andrikopoulos, S; Angus, PW; Brown, BE; Davies, MJ; Forbes, JM; Furness, JB; Herath, CB; Jia, Z; Leung, C; Rivera, LR, 2016) |
| "Fever was inhibited by BA most significantly by 3hours post-injection of zymosan (1." | 1.40 | Studies on the anti-inflammatory, analgesic and antipyrexic activities of betulinic acid derived from Tetracera potatoria. ( Oridupa, OA; Oyebanji, BO; Saba, AB, 2014) |
| "Colitis was induced by intrarectal inoculation of rats with 4% acetic acid for three consecutive days." | 1.40 | L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65. ( Farghaly, HS; Thabit, RH, 2014) |
| "Acute inflammation was produced by subplantar injection of 0." | 1.39 | Chemical constituents and antihistamine activity of Bixa orellana leaf extract. ( Ahmad, Z; Ee Cheng Lian, G; Kadir, AA; Somchit, MN; Yong, YK; Zakaria, ZA, 2013) |
| "Curcumin treatment was associated with amelioration of macroscopic and microscopic colitis sores, decreased MPO activity, and decreased MDA levels in acetic acid-induced colitis." | 1.39 | Effects of curcumin on apoptosis and oxidoinflammatory regulation in a rat model of acetic acid-induced colitis: the roles of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase. ( Akpolat, M; Cerkezkayabekir, A; Kizilay, G; Omurlu, IK; Sapmaz-Metin, M; Topcu-Tarladacalisir, Y; Uz, YH, 2013) |
| " In this regard, we carried out to evaluated both antinociceptive and anti-inflammatory activities in experimental models and assess the toxic effects of the acute (single dose) and subchronic (30 days) oral administration of dry extract of Dioscorea villosa in rodents." | 1.39 | Bioassay-guided evaluation of Dioscorea villosa - an acute and subchronic toxicity, antinociceptive and anti-inflammatory approach. ( Araújo, AA; Barreto, RS; de Albuquerque, RL; de Almeida, EB; Lima, AK; Lima, CM; Melo, MG; Moraes, VR; Nogueira, PC; Oliveira, DL; Oliveira, ER; Quintans-Júnior, LJ; Serafini, MR, 2013) |
| "Oleanolic acid (OA) is a triterpenoid known for its anti-inflammatory and anti-cancer properties; however, the anti-inflammatory effects of OA on lipopolysaccharide (LPS)-mediated pro-inflammatory responses have not been studied." | 1.39 | Anti-inflammatory effects of oleanolic acid on LPS-induced inflammation in vitro and in vivo. ( Bae, JS; Ku, SK; Lee, W; Song, KS; Yang, EJ, 2013) |
| "Pentoxifylline (PTX) has strong antyinflamatory effects, decreases TNF-alpha and other proinflammatory cytokines production." | 1.38 | Pentoxifylline modifies central and peripheral vagal mechanism in acute and chronic pain models. ( Dobrogowski, J; Nowak, Ł; Thor, PJ; Wordliczek, J; Zurowski, D, 2012) |
| " Brucine in MTAF was absorbed more completely than it alone at the same dosage of brucine after transdermal administration." | 1.38 | Analgesic and anti-inflammatory activity and pharmacokinetics of alkaloids from seeds of Strychnos nux-vomica after transdermal administration: effect of changes in alkaloid composition. ( Cai, BC; Cai, H; Chen, J; Chen, ZP; Liu, X; Lu, TL; Qu, YG; Wang, X; Xu, F, 2012) |
| "In addition, TFC reduced CFA-induced tactile hyperalgesia in a dose-dependent manner and the LD50 of TFC was determined to be 400 mg/kg." | 1.38 | Isolation and biological activity of triglycerides of the fermented mushroom of Coprinus Comatus. ( Guo, JY; Han, CC; Liu, ZQ; Ren, J; Shi, JL, 2012) |
| "Amentoflavone (CF-2) was isolated from the aqueous/n-butanol fraction." | 1.38 | Bioactivity guided isolation of analgesic and anti-inflammatory constituents of Cnestis ferruginea Vahl ex DC (Connaraceae) root. ( Adeyemi, OO; Agbaje, OE; Ishola, IO; Narender, T; Shukla, R, 2012) |
| "crassifolius for the treatment of pain and inflammation." | 1.38 | Anti-nociceptive and anti-inflammatory effects of Croton crassifolius ethanol extract. ( Fang, F; Wang, G; Yang, L; Yu, L; Zhao, J, 2012) |
| "URB937 is a peripherally restricted inhibitor of the anandamide-deactivating enzyme fatty-acid amide hydrolase (FAAH)." | 1.38 | Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier. ( Bertorelli, R; Guijarro, A; Moreno-Sanz, G; Oluyemi, O; Piomelli, D; Reggiani, A; Sasso, O, 2012) |
| "armatum in the treatment of inflammation and pain is warranted." | 1.37 | Antinociceptive and anti-inflammatory activities of ethyl acetate fraction from Zanthoxylum armatum in mice. ( Cai, CC; Deng, YX; Guo, T; Pan, SL; Wang, YL; Xie, H; Yao, CY, 2011) |
| " Secondly, we developed a sensitive and specific HPLC method to analyze 2', 4'-dihydroxychalcone (TFC, the mainly ingredient of FEO) in rat plasma to study the pharmacokinetic of TEC." | 1.37 | The studies of anti-inflammatory and analgesic activities and pharmacokinetics of Oxytropis falcate Bunge extraction after transdermal administration in rats. ( Cai, BC; Chen, HX; Chen, J; Chen, ZP; Liu, D; Lu, TL; Qu, MM; Xiao, YY, 2011) |
| " The pharmacokinetics and absolute bioavailability of FEO in rat, furthermore, was studied." | 1.37 | The studies of anti-inflammatory and analgesic activities and pharmacokinetics of Oxytropis falcate Bunge extraction after transdermal administration in rats. ( Cai, BC; Chen, HX; Chen, J; Chen, ZP; Liu, D; Lu, TL; Qu, MM; Xiao, YY, 2011) |
| " The inhibition of oedema formation increased with increasing dosage from 25 to 100mg/kg." | 1.37 | Analgesic effects and anti-inflammatory properties of the crude methanolic extract of Schwenckia americana Linn (Solanaceae). ( Abdullahi, N; Adebisi, I; Chika, A; Jimoh, AO; Umar, MT, 2011) |
| " The analgesic activity of the ethanolic extract and its fractions has been carried out by tail-flick method and writhing test at a dosage of 300 mg/kg po." | 1.37 | Anti-inflammatory and anti-nociceptive activities of ethanolic extract and its various fractions from Adiantum capillus veneris Linn. ( Alam, MM; Alam, MS; Gupta, A; Haider, S; Hamid, H; Nazreen, S, 2011) |
| "27%) at 300 mg/kg po dosage when compared to the standard drug Indomethacin (63." | 1.37 | Anti-inflammatory and anti-nociceptive activities of ethanolic extract and its various fractions from Adiantum capillus veneris Linn. ( Alam, MM; Alam, MS; Gupta, A; Haider, S; Hamid, H; Nazreen, S, 2011) |
| "Morin was shown to contain an in vivo anti-inflammatory activity using a carrageenan-induced air pouch model in mice." | 1.36 | Evaluation of the antiangiogenic, anti-inflammatory, and antinociceptive activities of morin. ( Jung, HJ; Kim, SJ; Lim, CJ; Park, EH; Song, YS, 2010) |
| "Thalidomide was also effective in reducing TNFalpha levels thus contributing to its antiepileptic activity." | 1.35 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| "Inflammation was associated with decreased threshold to PTZ induced seizure." | 1.35 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| "There is higher incidence of seizures among patients with chronic inflammatory disease." | 1.35 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| "Ketorolac is a non-steroidal anti-inflammatory drug." | 1.34 | Ketorolac-dextran conjugates: synthesis, in vitro and in vivo evaluation. ( Chaturvedi, SC; Trivedi, P; Vyas, S, 2007) |
| "Ketorolac contents were evaluated by UV-spectrophotometric analysis." | 1.34 | Ketorolac-dextran conjugates: synthesis, in vitro and in vivo evaluation. ( Chaturvedi, SC; Trivedi, P; Vyas, S, 2007) |
| "Colitis was induced by intracolonic administration of acetic acid (5%) in Sprague-Dawley rats (200-250 g)." | 1.33 | Oxytocin ameliorates oxidative colonic inflammation by a neutrophil-dependent mechanism. ( Ercan, F; Gedik, N; Işeri, SO; Sağlam, B; Sener, G; Yeğen, BC, 2005) |
| "Melatonin is a hormone involved in the transduction of photoperiodic information, and appears to modulate a variety of neural and endocrine functions." | 1.33 | Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes. ( Cevík, H; Ercan, F; Erkanli, G; Işman, CA; Yeğen, BC, 2005) |
| "Pain is commonly associated with inflammation." | 1.33 | Differential effect of zileuton, a 5-lipoxygenase inhibitor, against nociceptive paradigms in mice and rats. ( Kulkarni, SK; Patil, CS; Singh, VP, 2005) |
| "The effect on carrageenan-induced mechanical hyperalgesia, and acetic acid-induced vascular permeability was also determined." | 1.33 | Differential effect of zileuton, a 5-lipoxygenase inhibitor, against nociceptive paradigms in mice and rats. ( Kulkarni, SK; Patil, CS; Singh, VP, 2005) |
| "Mucosal inflammation is a crucial factor for the recurrence of peptic ulcer." | 1.33 | Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils. ( Osaka, T; Sakurai, K; Yamasaki, K, 2005) |
| "Ulcer recurrence was examined at 60, 100, and 140 days after production of acetic acid-induced gastric ulcers in rats." | 1.33 | Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils. ( Osaka, T; Sakurai, K; Yamasaki, K, 2005) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid in male Sprague-Dawley rats." | 1.32 | Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis. ( Kang, JW; Kim, HJ; Kim, TW; La, JH; Sung, TS; Yang, IS, 2003) |
| "Pentoxifylline did not inhibit the nociceptive response in the hot plate test in mice." | 1.32 | Antihyperalgesic effect of pentoxifylline on experimental inflammatory pain. ( Benevides, VM; Brito, GA; Cunha, FQ; da Rocha, FA; Ferreira, SH; Poole, S; Ribeiro, RA; Sachs, D; Vale, ML, 2004) |
| "We propose that two separate hyperalgesia pathways exist, one of which is NK1 receptor dependent, whereas the other does not require intact substance P/NK1 signalling." | 1.31 | Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene. ( Cervero, F; De Felipe, C; Hunt, SP; Laird, JM; Olivar, T; Roza, C, 2000) |
| "In hexamethonium-pretreated animals, an atropine-sensitive component of [betaAla(8)]NKA(4-10)-induced colonic contractions was also evident." | 1.31 | Tachykinin NK(2) receptors and enhancement of cholinergic transmission in the inflamed rat colon: an in vivo motility study. ( Carini, F; Giuliani, S; Lecci, A; Maggi, CA; Tramontana, M, 2001) |
| " LD50 values of the infusion and maceration extracts were 3." | 1.31 | Antinociceptive, anti-inflammatory and acute toxicity effects of Zhumeria majdae extracts in mice and rats. ( Fadishei, M; Hosseinzadeh, H; Mahmoudi, M; Ramezani, M, 2002) |
| "The chloroformic fraction was the most interesting, exhibiting a good analgesic and anti-inflammatory activity." | 1.31 | Evaluation of the antinflammatory and analgesic activity of Sideritis canariensis var. pannosa in mice. ( Hernández-Pérez, M; Rabanal, RM, 2002) |
| "Acetic acid or 9% NaCl was injected intraperitoneally before the meal." | 1.30 | Tachykininergic mediation of viscerosensitive responses to acute inflammation in rats: role of CGRP. ( Buéno, L; Julia, V, 1997) |
| "Visceral pain was assessed by abdominal muscle contractions." | 1.30 | Tachykininergic mediation of viscerosensitive responses to acute inflammation in rats: role of CGRP. ( Buéno, L; Julia, V, 1997) |
| "Acute colitis was induced in male FVB mice (about 25 g) by intrarectal administration of 200 microliters of 0." | 1.30 | Induction of plasma hepatocyte growth factor in acute colitis of mice. ( Kawasaki, H; Kojo, H; Matsuno, M; Miura, K; Shiota, G; Umeki, K, 1997) |
| "Distal colitis was induced in rats by intrarectal administration of 4% acetic acid." | 1.30 | Acute experimental colitis decreases colonic circular smooth muscle contractility in rats. ( Dempsey, DT; Martin, JS; Myers, BS; Parkman, HP; Ryan, JP; Thomas, RM, 1997) |
| "Inflammation was induced by mucosal exposure to ethanol and acetic acid." | 1.30 | Inflammation modulates in vitro colonic myoelectric and contractile activity and interstitial cells of Cajal. ( Berezin, I; Huizinga, JD; Lu, G; Qian, X; Sarna, SK; Telford, GL, 1997) |
| " The dose-response experiments showed that the maximal anti-inflammatory and anti-exudative effects appeared at the dose of 3." | 1.28 | Parathyroid hormone fragment 1-34 inhibits drug-induced inflammation in various experimental models. ( Amico-Roxas, M; Caruso, A; Clementi, G; Cutuli, V; Fiore, CE; Prato, A, 1991) |
| "The analgesic and acute central nervous system (CNS) side effect potential of the enkephalinase inhibitor SCH 32615 (N-[L-(1-carboxy-2-phenyl)ethyl]-L-phenyl-alanine-beta-alanine) were evaluated after IV administration to mice, rats and squirrel monkeys." | 1.28 | Analgesic and acute central nervous system side effects of the intravenously administered enkephalinase inhibitor SCH 32615. ( Chipkin, RE; Coffin, VL, 1991) |
| " Twice daily dosing at 30 mg/kg p." | 1.27 | Pharmacological effects of SCH 30497--a novel analgesic substance. ( Barnett, A; Berger, JG; Chipkin, RE; Iorio, LC; Latranyi, MB, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (2.45) | 18.7374 |
| 1990's | 15 (6.12) | 18.2507 |
| 2000's | 58 (23.67) | 29.6817 |
| 2010's | 121 (49.39) | 24.3611 |
| 2020's | 45 (18.37) | 2.80 |
| Authors | Studies |
|---|---|
| Maruo, S | 1 |
| Kuriyama, I | 1 |
| Kuramochi, K | 1 |
| Tsubaki, K | 1 |
| Yoshida, H | 1 |
| Mizushina, Y | 1 |
| Fagundes, FL | 1 |
| Pereira, QC | 1 |
| Zarricueta, ML | 1 |
| Dos Santos, RC | 1 |
| Ghanim, AM | 1 |
| Girgis, AS | 1 |
| Kariuki, BM | 1 |
| Samir, N | 1 |
| Said, MF | 1 |
| Abdelnaser, A | 1 |
| Nasr, S | 1 |
| Bekheit, MS | 1 |
| Abdelhameed, MF | 1 |
| Almalki, AJ | 1 |
| Ibrahim, TS | 1 |
| Panda, SS | 1 |
| El-Ghannam, MS | 1 |
| Saad, MA | 1 |
| Nassar, NN | 1 |
| El-Yamany, MF | 1 |
| El-Bahy, AAZ | 1 |
| Bastaki, SMA | 2 |
| Amir, N | 2 |
| Adeghate, E | 2 |
| Ojha, S | 2 |
| Xia, T | 2 |
| Zhang, Z | 4 |
| Zhao, Y | 2 |
| Kang, C | 1 |
| Zhang, X | 3 |
| Tian, Y | 1 |
| Yu, J | 2 |
| Cao, H | 1 |
| Wang, M | 3 |
| Savran, M | 1 |
| Ascı, H | 1 |
| Erzurumlu, Y | 1 |
| Ozmen, O | 1 |
| Ilhan, I | 1 |
| Sırın, MC | 1 |
| Karakuyu, NF | 1 |
| Karaibrahimoglu, A | 1 |
| Noubissi, PA | 1 |
| Njilifac, Q | 1 |
| Fokam Tagne, MA | 1 |
| Dongmo Nguepi, MS | 1 |
| Foyet Fondjo, A | 1 |
| Kouémou Emégam, N | 1 |
| Ngakou Mukam, J | 1 |
| Zintchem, R | 1 |
| Wambe, H | 1 |
| Fankem, GO | 1 |
| Fotio Tonfack, A | 1 |
| Toukala, JP | 1 |
| Taiwe Sotoing, G | 1 |
| Kamgamg, R | 1 |
| Younis, M | 1 |
| Iqbal, J | 1 |
| Muhammad, S | 1 |
| Jan, SU | 1 |
| Jabbar, A | 1 |
| Mehjabeen, - | 1 |
| Qadir, A | 1 |
| Soomer Khan, N | 1 |
| Arslan, M | 1 |
| Shah, PA | 1 |
| Khan, Z | 1 |
| Li, X | 3 |
| Peng, X | 1 |
| Qiao, B | 1 |
| Peng, M | 1 |
| Deng, N | 1 |
| Yu, R | 1 |
| Tan, Z | 1 |
| Cinpolat, HY | 2 |
| Buğdaycı, G | 2 |
| Şengül, N | 2 |
| Astarcı, HM | 2 |
| Elbaz, EM | 1 |
| Essam, RM | 1 |
| Ahmed, KA | 1 |
| Safwat, MH | 1 |
| Liu, C | 1 |
| Han, M | 1 |
| Lv, F | 1 |
| Gao, Y | 2 |
| Wang, X | 3 |
| Guo, Y | 3 |
| Cheng, Y | 3 |
| Qian, H | 1 |
| Erarslan, AS | 1 |
| Ozmerdivenli, R | 1 |
| Sirinyıldız, F | 1 |
| Cevik, O | 2 |
| Gumus, E | 1 |
| Cesur, G | 1 |
| Şen, A | 1 |
| Ertaş, B | 1 |
| Yıldırım, A | 1 |
| Kayalı, DG | 1 |
| Akakın, D | 1 |
| Bitiş, L | 1 |
| Şener, G | 2 |
| Dawod Farhan, A | 1 |
| Al-Bayati, NY | 1 |
| Seoudi, SS | 1 |
| Allam, EA | 1 |
| El-Kamel, AH | 1 |
| Elkafrawy, H | 1 |
| El-Moslemany, RM | 1 |
| El Mahdy, RN | 1 |
| Nader, MA | 1 |
| Helal, MG | 1 |
| Abu-Risha, SE | 1 |
| Abdelmageed, ME | 1 |
| Ghasemi-Dehnoo, M | 2 |
| Amini-Khoei, H | 2 |
| Lorigooini, Z | 2 |
| AnjomShoa, M | 1 |
| Rafieian-Kopaei, M | 2 |
| Elbatreek, MH | 1 |
| Fathi, AM | 1 |
| Mahdi, I | 1 |
| Abdelfattah, MAO | 1 |
| Mahmoud, MF | 1 |
| Sobeh, M | 1 |
| Luan, L | 1 |
| Pan, H | 2 |
| Chen, Y | 1 |
| Ye, X | 1 |
| Hou, Z | 1 |
| Chen, S | 3 |
| Sabzevary-Ghahfarokhi, M | 1 |
| Alaaeldin, E | 1 |
| Refaat, H | 1 |
| Saber, EA | 1 |
| Aziz, NM | 1 |
| Abdel-Maqsoud, NMR | 1 |
| Aleem, MMAE | 1 |
| Kamel, MY | 1 |
| Mady, FM | 1 |
| Pan, Y | 1 |
| Lv, H | 1 |
| Feng, X | 1 |
| Zhou, S | 1 |
| Hu, H | 1 |
| Fan, F | 1 |
| Gong, S | 1 |
| Chen, P | 1 |
| Chu, Q | 1 |
| Alizadeh Nobakht, NA | 1 |
| Lashgari, NA | 1 |
| Momeni Roudsari, N | 1 |
| Niknejad, A | 1 |
| Khayatan, D | 1 |
| Tavakoli, S | 1 |
| Abdollahi, AR | 1 |
| Esmaealzadeh, N | 1 |
| Momtaz, S | 1 |
| Abdolghaffari, AH | 1 |
| Afridi, R | 1 |
| Khan, AU | 1 |
| Khalid, S | 1 |
| Shal, B | 1 |
| Rasheed, H | 1 |
| Ullah, MZ | 1 |
| Shehzad, O | 1 |
| Kim, YS | 1 |
| Khan, S | 1 |
| Osmakov, DI | 1 |
| Koshelev, SG | 1 |
| Palikov, VA | 1 |
| Palikova, YA | 1 |
| Shaykhutdinova, ER | 1 |
| Dyachenko, IA | 1 |
| Andreev, YA | 1 |
| Kozlov, SA | 1 |
| Pacheco, SDG | 1 |
| Gasparin, AT | 1 |
| Jesus, CHA | 1 |
| Sotomaior, BB | 1 |
| Ventura, ACSSB | 1 |
| Redivo, DDB | 1 |
| Cabrini, DA | 1 |
| Gaspari Dias, JF | 1 |
| Miguel, MD | 1 |
| Miguel, OG | 1 |
| da Cunha, JM | 1 |
| Iqbal, A | 1 |
| Din, SU | 1 |
| Bakht, J | 1 |
| Khan, IU | 1 |
| Shah, Z | 1 |
| Kumari, P | 1 |
| Kaur, S | 1 |
| Kaur, J | 1 |
| Bhatti, R | 1 |
| Singh, P | 1 |
| Sheethal, S | 1 |
| Ratheesh, M | 1 |
| Jose, SP | 1 |
| Asha, S | 1 |
| Krishnakumar, IM | 1 |
| Sandya, S | 1 |
| Girishkumar, B | 1 |
| Grace, J | 1 |
| Khaksarian, M | 1 |
| Mahmoudvand, H | 1 |
| Alipour, M | 1 |
| Naizi, M | 1 |
| Hasanvand, KH | 1 |
| Nadri, S | 1 |
| Yuan, HL | 1 |
| Zhao, YL | 1 |
| Qin, XJ | 1 |
| Liu, YP | 1 |
| Yu, HF | 1 |
| Zhu, PF | 1 |
| Jin, Q | 1 |
| Yang, XW | 1 |
| Luo, XD | 1 |
| V S, A | 1 |
| S K, K | 1 |
| Du, Y | 1 |
| Xie, L | 1 |
| Pu, Y | 1 |
| Yuan, J | 1 |
| Wang, Z | 2 |
| Zhang, T | 1 |
| Wang, B | 1 |
| Zhang, C | 1 |
| Huang, Y | 2 |
| Li, P | 1 |
| Chen, X | 1 |
| Liu, F | 1 |
| Hou, Q | 1 |
| Bahrami, G | 1 |
| Malekshahi, H | 1 |
| Miraghaee, S | 1 |
| Madani, H | 1 |
| Babaei, A | 1 |
| Ningaraju, S | 1 |
| Munawer, U | 1 |
| Raghavendra, VB | 1 |
| Balaji, KS | 1 |
| Melappa, G | 1 |
| Brindhadevi, K | 1 |
| Pugazhendhi, A | 1 |
| Wang, L | 1 |
| Gu, J | 1 |
| Zong, M | 1 |
| Zhang, Q | 1 |
| Li, H | 1 |
| Li, D | 1 |
| Mou, X | 1 |
| Liu, P | 2 |
| Liu, Y | 4 |
| Qiu, F | 1 |
| Zhao, F | 1 |
| Zahouani, Y | 1 |
| Ben Rhouma, K | 1 |
| Kacem, K | 1 |
| Sebai, H | 1 |
| Sakly, M | 1 |
| Alamgeer, - | 1 |
| Nasreen, P | 1 |
| Uttra, AM | 1 |
| Asif, H | 1 |
| Younis, W | 1 |
| Hasan, UH | 1 |
| Irfan, HM | 1 |
| Sharif, A | 1 |
| Rodríguez Basso, A | 1 |
| Carranza, A | 1 |
| Zainutti, VM | 1 |
| Bach, H | 1 |
| Gorzalczany, SB | 1 |
| Khlifi, A | 1 |
| Pecio, Ł | 1 |
| Lobo, JC | 1 |
| Melo, D | 1 |
| Ben Ayache, S | 1 |
| Flamini, G | 1 |
| Oliveira, MBPP | 1 |
| Oleszek, W | 1 |
| Achour, L | 1 |
| Duan, W | 1 |
| Li, S | 1 |
| Geng, B | 1 |
| Zheng, Y | 3 |
| Guo, C | 1 |
| Wang, Y | 3 |
| Zhang, S | 1 |
| Du, Z | 1 |
| Li, M | 3 |
| Ding, K | 1 |
| Du, P | 1 |
| Song, J | 1 |
| Qiu, H | 1 |
| Liu, H | 2 |
| Zhang, L | 2 |
| Zhou, J | 1 |
| Jiang, S | 1 |
| Liu, J | 1 |
| Liu, FY | 1 |
| Wen, J | 1 |
| Hou, J | 1 |
| Zhang, SQ | 1 |
| Sun, CB | 1 |
| Zhou, LC | 1 |
| Yin, W | 1 |
| Pang, WL | 1 |
| Wang, C | 1 |
| Ying, Y | 1 |
| Han, SS | 1 |
| Yan, JY | 1 |
| Li, CX | 1 |
| Yuan, JL | 1 |
| Xing, HJ | 1 |
| Yang, ZS | 1 |
| Li, Y | 2 |
| Jia, X | 1 |
| Tang, N | 1 |
| Tao, H | 1 |
| Xia, R | 1 |
| Mohamed, NI | 1 |
| Suddek, GM | 1 |
| El-Kashef, DH | 1 |
| Boakye-Gyasi, E | 1 |
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| Abotsi, WKM | 1 |
| Ameyaw, EO | 1 |
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| Hussain, L | 1 |
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| Freitas, CDT | 2 |
| Sousa-Filho, LM | 1 |
| Lima, MSCS | 1 |
| Pereira, ACTC | 1 |
| Ferreira, GP | 1 |
| Lopes, FES | 1 |
| Silva, RO | 1 |
| Barbosa, ALDR | 2 |
| Oliveira, JS | 2 |
| Nesterova, YV | 2 |
| Povet'eva, TN | 1 |
| Zibareva, LN | 1 |
| Suslov, NI | 2 |
| Zueva, EP | 1 |
| Aksinenko, SG | 1 |
| Afanas'eva, OG | 1 |
| Krylova, SG | 1 |
| Amosova, EN | 1 |
| Rybalkina, OY | 1 |
| Lopatina, KA | 1 |
| Poorvashree, J | 1 |
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| Palit, P | 1 |
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| Roychoudhury, S | 1 |
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| Barbosa, MU | 2 |
| Silva, MA | 1 |
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| Beh, BK | 1 |
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| Oliveira, ER | 1 |
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| Quintans-Júnior, LJ | 1 |
| Araújo, AA | 1 |
| Sayyed, HG | 1 |
| Jaumdally, RJ | 1 |
| Idriss, NK | 1 |
| El Sers, DA | 1 |
| Blann, A | 1 |
| Jin, Y | 1 |
| Zhu, HB | 1 |
| Xu, ST | 1 |
| Xia, YX | 1 |
| Chen, Z | 1 |
| Liao, L | 1 |
| Wu, L | 1 |
| Negoro, T | 1 |
| Kin, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Vinegar Consumption on 24-hour Urinary Risk Factors Associated With Calcium Oxalate Urinary Stone Formation: a Randomised Controlled Trial[NCT02649140] | 50 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for acetic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
Regeneration and the mechanism of epidermal tumor promotion.
Topics: Acetates; Acetic Acid; Animals; Carcinogens; Cell Differentiation; Connective Tissue Cells; Diterpen | 1985 |
1 trial available for acetic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
Anxiolytic and anti-colitis effects of Moringa oleifera leaf-aqueous extract on acetic acid-induced colon inflammation in rat.
Topics: Acetic Acid; Animals; Anti-Anxiety Agents; Antioxidants; Colon; Glutathione; Inflammation; Moringa o | 2022 |
243 other studies available for acetic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; DNA Polymerase beta; Enz | 2011 |
Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation.
Topics: Acetic Acid; Animals; Anthocyanins; Antioxidants; Biomarkers; Cyclooxygenase 1; Disease Models, Anim | 2021 |
Design and synthesis of ibuprofen-quinoline conjugates as potential anti-inflammatory and analgesic drug candidates.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cycloox | 2022 |
Linagliptin ameliorates acetic acid-induced colitis via modulating AMPK/SIRT1/PGC-1α and JAK2/STAT3 signaling pathway in rats.
Topics: Acetic Acid; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Colitis; Cytokines; D | 2022 |
Lycopodium Mitigates Oxidative Stress and Inflammation in the Colonic Mucosa of Acetic Acid-Induced Colitis in Rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Colitis; Colitis, Ulcerat | 2022 |
The anti-diabetic activity of polyphenols-rich vinegar extract in mice via regulating gut microbiota and liver inflammation.
Topics: Acetic Acid; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gastrointestinal M | 2022 |
"Theranekron: A Novel Anti-inflammatory Candidate for Acetic Acid-Induced Colonic Inflammation in Rats".
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis; Colon; Female; Inflammation; Inflammatory B | 2022 |
Evaluation of anti-inflammatory and analgesic effects of Hertia intermedia (Boiss.) Kuntze extract.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Asteraceae; Carrageenan; Edema | 2022 |
Gut-Kidney Impairment Process of Adenine Combined with
Topics: Acetic Acid; Adenine; Animals; Bacteroides; Colitis; Creatinine; Diarrhea; Disease Models, Animal; F | 2022 |
A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid.
Topics: Acetic Acid; Animals; Colitis; Colon; Inflammation; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenes | 2023 |
A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid.
Topics: Acetic Acid; Animals; Colitis; Colon; Inflammation; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenes | 2023 |
A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid.
Topics: Acetic Acid; Animals; Colitis; Colon; Inflammation; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenes | 2023 |
A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid.
Topics: Acetic Acid; Animals; Colitis; Colon; Inflammation; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenes | 2023 |
Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia activity.
Topics: Acetic Acid; Acetylcholinesterase; Animals; Antioxidants; Cognitive Dysfunction; Colitis; Colitis, U | 2023 |
Study on the Cellular Anti-Inflammatory Effect of Torularhodin Produced by
Topics: Acetic Acid; Anti-Inflammatory Agents; Basidiomycota; Carotenoids; Inflammation; Lipopolysaccharides | 2023 |
Therapeutic and prophylactic role of vitamin D and curcumin in acetic acid-induced acute ulcerative colitis model.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Colitis, Ulcerative; Colon; C | 2023 |
Cotinus coggygria Scop. Attenuates Acetic Acid-Induced Colitis in Rats by Regulation of Inflammatory Mediators.
Topics: Acetic Acid; Anacardiaceae; Animals; Antioxidants; Colitis; Colon; Cytokines; Humans; Inflammation; | 2023 |
Reduce the Changes in Histological Features of Colon Resulting from Induced Ulcerative Colitis in Mice by Worm Antigens.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Inflammation; Male; Mice | 2022 |
Targeted delivery of budesonide in acetic acid induced colitis: impact on miR-21 and E-cadherin expression.
Topics: Acetic Acid; Animals; Budesonide; Caco-2 Cells; Cadherins; Colitis; Humans; Hyaluronic Acid; Inflamm | 2023 |
Eicosapentaenoic acid mitigates ulcerative colitis-induced by acetic acid through modulation of NF-κB and TGF-β/ EGFR signaling pathways.
Topics: Acetic Acid; Animals; Antioxidants; Colitis, Ulcerative; Colon; Eicosapentaenoic Acid; ErbB Receptor | 2023 |
Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Inflammation; Lipopolysacch | 2023 |
Thymus satureioides Coss. combats oral ulcer via inhibition of inflammation, proteolysis, and apoptosis.
Topics: Acetic Acid; Animals; Apoptosis; Caspase 3; Cyclooxygenase 2; Humans; Inflammation; Matrix Metallopr | 2023 |
Role of extracted phytochemicals from
Topics: Acetic Acid; Animals; Catechin; Colitis; Inflammation; Mice; Rosa | 2023 |
Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Inflammation; Male; NF-kappa B; Ni | 2023 |
Co-administration of Thymoquinone and Propolis in Liposomal Formulations as a Potential Approach for Treatment of Acetic Acid-Induced Ulcerative Colitis: Physiological and Histopathological Analysis.
Topics: Acetic Acid; Colitis; Colitis, Ulcerative; Humans; Inflammation; Liposomes; Propolis | 2023 |
Epigallocatechin gallate (EGCG) alleviates the inflammatory response and recovers oral microbiota in acetic acid-induced oral inflammation mice.
Topics: Acetic Acid; Animals; Catechin; Cytokines; Humans; Inflammation; Mice; Microbiota; Tea | 2023 |
Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Colon; Inflammation; Inflamma | 2023 |
Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chronic Pain; Disease Mo | 2019 |
Alkaloid Lindoldhamine Inhibits Acid-Sensing Ion Channel 1a and Reveals Anti-Inflammatory Properties.
Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Animals; Anti-Inflammator | 2019 |
Antinociceptive and Anti-Inflammatory Effects of Bixin, a Carotenoid Extracted from the Seeds of Bixa orellana.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Bixaceae; Carotenoids; Carrageenan; Dise | 2019 |
Anti-inflammatory, anti-pyretic and analgesic activities of Tamarix dioica.
Topics: Acetic Acid; Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antifungal Agents | 2019 |
Modification of the lead molecule: Tryptophan and piperidine appended triazines reversing inflammation and hyeperalgesia in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 In | 2020 |
Anti-Ulcerative Effect of Curcumin-Galactomannoside Complex on Acetic Acid-Induced Experimental Model by Inhibiting Inflammation and Oxidative Stress.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Colitis, Ulcerative; Curcumin; Drug Combinations; Galactose | 2020 |
Effect of Nectaroscordum koelzi Methanolic Extract on Acute and Chronic Inflammation in Male Mice.
Topics: Acetic Acid; Allium; Animals; Anti-Inflammatory Agents; Capillary Permeability; Disease Models, Anim | 2021 |
Anti-inflammatory and analgesic activities of Neolamarckia cadamba and its bioactive monoterpenoid indole alkaloids.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; Disease Models, | 2020 |
Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Immunity; Inflammation; Mice; Phloretin; Rats; Rats, Wistar; R | 2021 |
Effects of Paeonol and Gastroretention Tablets of Paeonol on Experimental Gastric Ulcers and Intestinal Flora in Rats.
Topics: Acetic Acid; Acetophenones; Animals; Antioxidants; Catalase; Gastric Acid; Gastric Mucosa; Gastroint | 2020 |
Ginger relieves intestinal hypersensitivity of diarrhea predominant irritable bowel syndrome by inhibiting proinflammatory reaction.
Topics: Acetic Acid; Animals; China; Diarrhea; Disease Models, Animal; Inflammation; Irritable Bowel Syndrom | 2020 |
Improving Animal Model of Induced Colitis by Acetic Acid in Terms of Fibrosis and Inflammation Incidence in the Colon.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Fibrosis; Incidence; Inflammation; Rat | 2022 |
Chaetomium globosum extract mediated gold nanoparticle synthesis and potent anti-inflammatory activity.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Catechin; Chaetomium; | 2021 |
Anti-inflammatory action of physalin A by blocking the activation of NF-κB signaling pathway.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Disease Models, | 2021 |
Aqueous Leaf Extract of
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Inflammation; Oxidative Str | 2021 |
Evaluation of anti-inflammatory and analgesic activities of aqueous methanolic extract of Ranunculus muricatus in albino mice.
Topics: Acetic Acid; Albumins; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, A | 2020 |
Pharmacologycal activity of peperina (Minthostachys verticillata) on gastrointestinal tract.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Behavior, Animal; Capsaicin; Castor Oil; Colitis, Ul | 2021 |
Leaves of Cleome amblyocarpa Barr. And Murb. And Cleome arabica L.: Assessment of nutritional composition and chemical profile (LC-ESI-MS/MS), anti-inflammatory and analgesic effects of their extracts.
Topics: Acetic Acid; Africa, Northern; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carr | 2021 |
Polyphenol-rich vinegar extract regulates intestinal microbiota and immunity and prevents alcohol-induced inflammation in mice.
Topics: Acetic Acid; Animals; China; Ethanol; Gastrointestinal Microbiome; Inflammation; Mice; Plant Extract | 2021 |
Crataegus pinnatifida polysaccharide alleviates colitis via modulation of gut microbiota and SCFAs metabolism.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Bacteroides; Cell Line; Colitis; Colon; Crataegus; D | 2021 |
Nerolidol, a sesquiterpene, attenuates oxidative stress and inflammation in acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Colitis; Cytoki | 2021 |
Polyphenols Extracted from Shanxi-Aged Vinegar Inhibit Inflammation in LPS-Induced RAW264.7 Macrophages and ICR Mice via the Suppression of MAPK/NF-κB Pathway Activation.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Nucleus Shape; Cell Shape; Cell Surv | 2021 |
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Topics: Acetic Acid; Animals; Aorta; Atherosclerosis; Benzyl Alcohols; Butyric Acid; Disease Models, Animal; | 2021 |
Melanoidins, extracted from Chinese traditional vinegar powder, inhibit alcohol-induced inflammation and oxidative stress in macrophages via activation of SIRT1 and SIRT3.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; China; Ethanol; Humans; Inflammation; Macrophages; M | 2021 |
Molsidomine alleviates acetic acid-induced colitis in rats by reducing oxidative stress, inflammation and apoptosis.
Topics: Acetic Acid; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulator | 2021 |
Hydro-ethanolic leaf extract of Ziziphus abyssinica Hochst Ex A. Rich (Rhamnaceae) exhibits anti-nociceptive effects in murine models.
Topics: Acetic Acid; Africa; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; D | 2017 |
Report: Analgesic and anti-inflammatory activity of aqueous-methanolic extract of Aerva javanica.
Topics: Acetic Acid; Amaranthaceae; Analgesics; Animals; Anti-Inflammatory Agents; Chondrus; Disease Models, | 2017 |
Effects of quinine on gastric ulcer healing in Wistar rats.
Topics: Acetic Acid; Animals; Cinchona; Gastric Mucosa; Inflammation; Lipid Peroxidation; Male; Mucus; Oxida | 2017 |
Proteins from the Rhinella schneideri parotoid gland secretion exhibit anti-nociceptive effect against nociception induced by inflammation.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Bufonidae; Disease Models, Animal; Edema | 2017 |
Anti-Inflammatory and Analgesic Activities of the Complex of Flavonoids from Lychnis chalcedonica L.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Diclofenac; Female; Flavono | 2017 |
Novel drug delivery of dual acting prodrugs of hydroxychloroquine with aryl acetic acid NSAIDs: Design, kinetics and pharmacological study.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, R | 2017 |
Attenuation of nociceptive pain and inflammatory disorders by total steroid and terpenoid fraction of Euphorbia tirucalli Linn root in experimental in vitro and in vivo model.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Cell Line, Tumor; Cytokines; | 2018 |
Topical action of Buriti oil (Mauritia flexuosa L.) in myositis induced in rats.
Topics: Acetic Acid; Administration, Topical; Animals; Arecaceae; Carotenoids; Disease Models, Animal; Fibro | 2017 |
Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice.
Topics: Acetaminophen; Acetic Acid; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cocos; In | 2018 |
LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrage | 2018 |
Protection afforded by methanol extract of Calotropis procera latex in experimental model of colitis is mediated through inhibition of oxidative stress and pro-inflammatory signaling.
Topics: Acetic Acid; Animals; Calotropis; Colitis; Disease Models, Animal; Female; Inflammation; Inflammatio | 2019 |
Proteins from Plumeria pudica latex exhibit protective effect in acetic acid induced colitis in mice by inhibition of pro-inflammatory mechanisms and oxidative stress.
Topics: Acetic Acid; Animals; Apocynaceae; Colitis; Colon; Cytokines; Glutathione; Inflammation; Interleukin | 2019 |
Chemical constituents and antihistamine activity of Bixa orellana leaf extract.
Topics: Acetic Acid; Animals; Bixaceae; Capillary Permeability; Down-Regulation; Edema; Histamine; Histamine | 2013 |
Dietary component p-coumaric acid suppresses monosodium urate crystal-induced inflammation in rats.
Topics: Acetic Acid; Acid Phosphatase; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; beta-Glu | 2013 |
Systemic synergism between codeine and morphine in three pain models in mice.
Topics: Acetic Acid; Acute Pain; Analgesics, Opioid; Animals; Behavior, Animal; Codeine; Disease Models, Ani | 2013 |
Effects of curcumin on apoptosis and oxidoinflammatory regulation in a rat model of acetic acid-induced colitis: the roles of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Colitis, Ulcerative; Colon; | 2013 |
Anti-inflammatory and analgesic activities of Melanthera scandens.
Topics: Acetic Acid; Albumins; Analgesics; Animals; Anti-Inflammatory Agents; Asteraceae; Carrageenan; Edema | 2012 |
Pentoxifylline modifies central and peripheral vagal mechanism in acute and chronic pain models.
Topics: Acetic Acid; Acute Pain; Animals; Anti-Inflammatory Agents; Chronic Pain; Cytokines; Hyperalgesia; I | 2012 |
Bioassay-guided evaluation of Dioscorea villosa - an acute and subchronic toxicity, antinociceptive and anti-inflammatory approach.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Biological Assay; | 2013 |
The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat.
Topics: Acetic Acid; Animals; Biomarkers; Colitis; Gene Expression Regulation; Inflammation; Male; Melatonin | 2013 |
The anti-inflammatory and anti-nociceptive activities of Patrinia villosa and its mechanism on the proinflammatory cytokines of rats with pelvic inflammation.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; | 2012 |
Comparison of active constituents, acute toxicity, anti-nociceptive and anti-inflammatory activities of Porana sinensis Hemsl., Erycibe obtusifolia Benth. and Erycibe schmidtii Craib.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Convolvulaceae; Ear; Edema; | 2013 |
Potentiated macrophage activation by acid sensing under low adiponectin levels.
Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Adiponectin; Amiloride; A | 2014 |
Anti-inflammatory and analgesic activity of R.A.P. (Radix Angelicae Pubescentis) ethanol extracts.
Topics: Acetic Acid; Analgesics; Angelica; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, A | 2013 |
Evaluation of anti-inflammatory, analgesic, and antipyretic effects of ethanolic extract of Pedalium murex Linn. fruits.
Topics: Acetic Acid; Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents; Antipyretics; Carr | 2013 |
Analgesic effects of Huwentoxin-IV on animal models of inflammatory and neuropathic pain.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Formaldehyde; Inflammati | 2014 |
Anti-inflammatory and antinociceptive effects of Sterculia striata A. St.-Hil. & Naudin (Malvaceae) in rodents.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Carrageenan; Dextrans; Edema; | 2014 |
Analgesic and anti-inflammatory activities of the 2,8-dihydroxy-1,6-dimethoxyxanthone from Haploclathra paniculata (Mart) Benth (Guttiferae).
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Carrag | 2014 |
Alpha amylase enzyme inhibitory and anti-inflammatory effect of Lawsonia inermis.
Topics: Acetic Acid; alpha-Amylases; Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; | 2013 |
Study on analgesic and anti-inflammatory properties of Cordia myxa fruit hydro-alcoholic extract.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Cordia; Disease Models | 2013 |
Anti-allergic rhinitis effect of caffeoylxanthiazonoside isolated from fruits of Xanthium strumarium L. in rodent animals.
Topics: Acetic Acid; Analgesics; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Caffeic Acids; Dis | 2014 |
Studies on the anti-inflammatory, analgesic and antipyrexic activities of betulinic acid derived from Tetracera potatoria.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Betulinic Acid; Carrageena | 2014 |
Antinociceptive and anti-inflammatory activities of the sesame oil and sesamin.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Dioxoles; Edema; Formaldehy | 2014 |
Synthesis and analgesic effects of μ-TRTX-Hhn1b on models of inflammatory and neuropathic pain.
Topics: Acetic Acid; Analgesics; Animals; Disease Models, Animal; Formaldehyde; HEK293 Cells; Humans; Inflam | 2014 |
L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65.
Topics: Acetic Acid; Animals; Arginine; Body Weight; Colitis; Colon; Guanidines; Inflammation; Male; NF-kapp | 2014 |
Anti-inflammatory and antinociceptive activity of Urera aurantiaca.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Female; Free Radical | 2015 |
Antinociceptive and anti-inflammatory activities of Geranium bellum and its isolated compounds.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Ellagic Acid; Female | 2014 |
Anti-inflammatory and analgesic effects of pyeongwisan on LPS-stimulated murine macrophages and mouse models of acetic acid-induced writhing response and xylene-induced ear edema.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Cyclooxygenase | 2015 |
Anti-nociceptive, anti-inflammatory and toxicological evaluation of Fang-Ji-Huang-Qi-Tang in rodents.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Aristolochia; Aristolochic Acids; Astrag | 2015 |
Extracts of Leptadenia hastata Leaf, a Famine Food and Traditional Remedy for Furuncles, Suppress Inflammation in Murine Models.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Apocynaceae; Arthritis; Capillary Permeability; Carr | 2016 |
Design and Synthesis of Mannich bases as Benzimidazole Derivatives as Analgesic Agents.
Topics: Acetic Acid; Analgesics; Animals; Benzimidazoles; Diclofenac; Disease Models, Animal; Drug Evaluatio | 2015 |
Anti-inflammatory activity of Buchholzia coriacea Engl. (Capparaceae) leaf extract: evaluation of components of the inflammatory response involved.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Capillary Permeability; Capparaceae; Cell Membrane; | 2015 |
Antipyretic, anti-inflammatory and analgesic activity of Acacia hydaspica R. Parker and its phytochemical analysis.
Topics: Acacia; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Carrageenan; Edema | 2015 |
Antinociceptive and anti-tussive activities of the ethanol extract of the flowers of Meconopsis punicea Maxim.
Topics: Acetic Acid; Alkaloids; Ammonia; Analgesics; Animals; Anti-Inflammatory Agents; Cough; Flavonoids; F | 2015 |
In Vivo Analgesic and Antipyretic Activities of N-Butanol and Water Fractions of Ocimum Suave Aqueous Leaves Extract in Mice.
Topics: 1-Butanol; Acetic Acid; Analgesics; Animals; Antipyretics; Dose-Response Relationship, Drug; Ethiopi | 2015 |
Observing Anti-inflammatory and Anti-nociceptive Activities of Glycyrrhizin Through Regulating COX-2 and Pro-inflammatory Cytokines Expressions in Mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Cyc | 2015 |
Analgesic and Anti-Inflammatory Properties of Gelsolin in Acetic Acid Induced Writhing, Tail Immersion and Carrageenan Induced Paw Edema in Mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Diclofenac; Disease Models, | 2015 |
Antinociceptive and anti-inflammatory potentials of kolaviron: mechanisms of action.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Atropine; Carrageenan; Edema; Female; Fl | 2016 |
Analgesic, anti-inflammatory and anti-platelet activities of Buddleja crispa.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Blood Platelets; Carra | 2016 |
Non-neuronal, but atropine-sensitive ileal contractile responses to short-chain fatty acids: age-dependent desensitization and restoration under inflammatory conditions in mice.
Topics: Acetic Acid; Acetylcholine; Acetylcholinesterase; Age Factors; Animals; Atropine; Choline O-Acetyltr | 2016 |
Comparative pharmaceutical study on colon targeted micro-particles of celecoxib: in-vitro-in-vivo evaluation.
Topics: Acetic Acid; Acrylic Resins; Animals; Celecoxib; Chemistry, Pharmaceutical; Colon; Colonic Neoplasms | 2016 |
Pomegranate seed oil nanoemulsions improve the photostability and in vivo antinociceptive effect of a non-steroidal anti-inflammatory drug.
Topics: Abdomen; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Constriction, Pa | 2016 |
Phytochemical screening, safety evaluation, anti-inflammatory and analgesic studies of the leaf extracts of Sterculia tragacantha.
Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Female; Flavonoi | 2016 |
Design and Synthesis of 2-(Arylmethylideneamino) Isoindolines as New Potential Analgesic and Anti-Inflammatory Agents: A Molecular Hybridization Approach.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Edema; Infla | 2016 |
Analgesic and anti-inflammatory actions on bradykinin route of a polysulfated fraction from alga Ulva lactuca.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Bradykinin; Carrageenan; Chemical Fracti | 2016 |
Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease.
Topics: Acetic Acid; Animals; Cholesterol; Diet, High-Fat; Disease Progression; Fatty Liver; Fructose; Glyca | 2016 |
Goat whey ameliorates intestinal inflammation on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Goats; Humans; Inflammation; Peroxidase; Rats; Rats, Wistar; T | 2016 |
Bacterial short-chain fatty acid metabolites modulate the inflammatory response against infectious bacteria.
Topics: Acetic Acid; Acrylamides; Aggregatibacter actinomycetemcomitans; Animals; Butyrates; Cytokines; Hist | 2017 |
Protective effect of cardamonin against acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Caspase 3; Chalcones; Colitis, Ulcerative; Colon; Cy | 2017 |
In vivo analgesic, antipyretic and anti-inflammatory potential of leaf extracts and fractions of Eria javanica.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Carrageenan; Edema; Female | 2017 |
Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat.
Topics: Acetic Acid; Analysis of Variance; Animals; Arthritis; Colitis; Cyclooxygenase Inhibitors; Cytokines | 2008 |
Profound reduction of somatic and visceral pain in mice by intrathecal administration of the anti-migraine drug, sumatriptan.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Blood-Brain Barrier; Carrageenan; Drug Evaluation, P | 2008 |
Anti-inflammatory and analgesic properties in a rodent model of a (1-->3),(1-->6)-linked beta-glucan isolated from Pleurotus pulmonarius.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Capillary Permeability | 2008 |
Effects of bioactive substances from tall delphinium on the development of acute inflammation of different genesis.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Inflammatory Agents; Carrageenan; Delphinium; Histamine; I | 2008 |
The analgesic and anti-inflammatory activities of the extract of Albizia lebbeck in animal model.
Topics: Acetic Acid; Administration, Oral; Albizzia; Analgesics; Animals; Anti-Inflammatory Agents; Carragee | 2009 |
Anti-inflammatory phenylpropanoid glycosides from Clerodendron trichotomum leaves.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Capillary Permeability; Carragee | 2009 |
The effects of the selective and non-peptide CXCR2 receptor antagonist SB225002 on acute and long-lasting models of nociception in mice.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetic Acid; Animals; Arthritis, Experimental; Carrageenan; | 2010 |
Anti-inflammatory and analgesic effects of ethanol and aqueous extracts of Pterocephalus hookeri (C.B. Clarke) Höeck.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Dip | 2009 |
Synthesis of novel 1,3,4-oxadiazole derivatives and their biological properties.
Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Carrageenan; Dise | 2009 |
Anti-nociceptive and anti-inflammatory activity of sophocarpine.
Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carra | 2009 |
Anti-inflammatory, anti-angiogenic and anti-nociceptive activities of an ethanol extract of Salvia plebeia R. Brown.
Topics: Acetic Acid; Analgesics; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; B | 2009 |
Anti-inflammatory and analgesic properties of cis-mulberroside A from Ramulus mori.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cell Line; Disaccharides; D | 2010 |
Evaluation of the antiangiogenic, anti-inflammatory, and antinociceptive activities of morin.
Topics: Acetic Acid; Analgesics; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Behavior, Anima | 2010 |
Effect of Lactobacillus plantarum and Pseudomonas aeruginosa culture supernatants on polymorphonuclear damage and inflammatory response.
Topics: Acetic Acid; Acyl-Butyrolactones; Animals; Antibiosis; Endotoxins; Humans; Inflammation; Lactobacill | 2010 |
Anti-inflammatory and anti-arthritic activity of total flavonoids of the roots of Sophora flavescens.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Behavior, Animal; Cell Line; | 2010 |
Assessment of anti-inflammatory and antinociceptive activities of Olea europaea L.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Capillary Permeability; C | 2010 |
Analgesic and anti-inflammatory effects of Pistacia integerrima extracts in mice.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Diclofenac; Dose-Respons | 2010 |
Antipyretic, analgesic, anti-inflammatory and antioxidant activities of two major chromenes from Melicope lunu-ankenda.
Topics: Acetic Acid; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Antioxidants; | 2010 |
Antinociceptive and anti-inflammatory activities of lectin from marine red alga Pterocladiella capillacea.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Disease M | 2010 |
Antinociceptive and antiinflammatory activities of Adiantum latifolium Lam.: evidence for a role of IL-1β inhibition.
Topics: Acetic Acid; Adiantum; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Behavior, An | 2011 |
Anti-inflammatory and analgesic effect of plumbagin through inhibition of nuclear factor-κB activation.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykini | 2010 |
Antiinflammatory, analgesic and antipyretic activities of ethanolic root extract of Croton zambesicus.
Topics: Acetic Acid; Amphetamine; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal | 2010 |
Evidence for the complementary and synergistic effects of the three-alkaloid combination regimen containing berberine, hypaconitine and skimmianine on the ulcerative colitis rats induced by trinitrobenzene-sulfonic acid.
Topics: Acetic Acid; Aconitine; Alkaloids; Analgesics; Animals; Antidiarrheals; Behavior, Animal; Berberine; | 2011 |
Experimental mild pulmonary inflammation promotes the development of exercise-induced pulmonary haemorrhage.
Topics: Acetic Acid; Animals; Bronchoalveolar Lavage; Hemorrhage; Horse Diseases; Horses; Inflammation; Lung | 2010 |
Antinociceptive and anti-inflammatory activities of ethyl acetate fraction from Zanthoxylum armatum in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Dose-Response Relation | 2011 |
The studies of anti-inflammatory and analgesic activities and pharmacokinetics of Oxytropis falcate Bunge extraction after transdermal administration in rats.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Biological Availabilit | 2011 |
Anti-inflammatory and analgesic activity of different extracts of Commiphora myrrha.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Commiphora; Dinoprosto | 2011 |
Genomic loci and candidate genes underlying inflammatory nociception.
Topics: Acetic Acid; Animals; Chromosome Mapping; Confidence Intervals; Databases, Genetic; Female; Genome; | 2011 |
Effect of nitric oxide inhibitor and donor substances on the inflammatory process caused by endodontic irrigants.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Citric Acid; Edetic Acid; Enzyme Inhibitors; Inflamm | 2011 |
Triterpenes involved in the anti-inflammatory effect of ethanolic extract of Pterodon emarginatus Vogel stem bark.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Chemical Fractionation; Croton Oil; Dise | 2012 |
Analgesic effects and anti-inflammatory properties of the crude methanolic extract of Schwenckia americana Linn (Solanaceae).
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Re | 2011 |
Anti-inflammatory and analgesic activities of ethanolic extract of Sphaeranthus indicus Linn.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Asteraceae; Carrageenan; Disease Models, | 2011 |
Anti-inflammatory and analgesic activity of protocatechuic acid in rats and mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2011 |
Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (H(2)LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H(2)LASSBio-1064) and their zinc(II) complexes.
Topics: Acetic Acid; Aldehydes; Analgesics; Animals; Anti-Inflammatory Agents; Coordination Complexes; Cryst | 2011 |
Experimental study on anti-inflammatory activity of a TCM recipe consisting of the supercritical fluid CO2 extract of Chrysanthemum indicum, Patchouli Oil and Zedoary Turmeric Oil in vivo.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carbon Dioxide; Carrageenan; | 2012 |
Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Drug Evaluation, Preclinica | 2012 |
Antipyretic, anti-inflammatory and analgesic properties of nilavembu kudineer choornam: a classical preparation used in the treatment of chikungunya fever.
Topics: Acetic Acid; Animals; Carrageenan; Case-Control Studies; Disease Models, Animal; Dose-Response Relat | 2011 |
Anti-inflammatory activities and mechanisms of action of the petroleum ether fraction of Rosa multiflora Thunb. hips.
Topics: Acetic Acid; Alkanes; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Diseas | 2011 |
Anti-inflammatory and anti-nociceptive activities of ethanolic extract and its various fractions from Adiantum capillus veneris Linn.
Topics: Acetic Acid; Adiantum; Analgesics; Animals; Anti-Inflammatory Agents; Edema; Ethanol; Female; Inflam | 2011 |
Diuretic, anti-inflammatory, and analgesic activities of the ethanol extract from Cynoglossum lanceolatum.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Boraginaceae; Carrageenan; Disease Model | 2012 |
Analgesic and anti-inflammatory activity and pharmacokinetics of alkaloids from seeds of Strychnos nux-vomica after transdermal administration: effect of changes in alkaloid composition.
Topics: Acetic Acid; Administration, Cutaneous; Alkaloids; Analgesics; Animals; Anti-Inflammatory Agents; Be | 2012 |
Gelsenicine from Gelsemium elegans attenuates neuropathic and inflammatory pain in mice.
Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Behavior, Animal; Drugs, Chinese Herbal; Formaldehyde; | 2011 |
Wound healing and anti-inflammatory activities of the Michauxia L'Hérit (Campanulaceae) species native to Turkey.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Campanulaceae; Cap | 2012 |
Wound healing and anti-inflammatory properties of Ranunculus pedatus and Ranunculus constantinapolitanus: a comparative study.
Topics: Acetic Acid; Animals; Anti-Infective Agents; Capillary Permeability; Disease Models, Animal; Hydroxy | 2012 |
Appraisal on the wound healing and anti-inflammatory activities of the essential oils obtained from the cones and needles of Pinus species by in vivo and in vitro experimental models.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Capillary Permeability; Disease Models, Animal; Enzy | 2012 |
Isolation of active constituents from cherry laurel (Laurocerasus officinalis Roem.) leaves through bioassay-guided procedures.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Biological Assay; Capilla | 2012 |
Antioxidant, anti-inflammatory and anti-nociceptive effects of Ammannia baccifera L. (Lythracceae), a folklore medicinal plant.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Biphenyl | 2012 |
Anti-nociceptive and anti-inflammatory properties of the ethanolic extract of Lagenaria breviflora whole fruit in rat and mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cucurbitaceae; Disease Mode | 2011 |
Carnosine has antinociceptive properties in the inflammation-induced nociceptive response in mice.
Topics: Acetic Acid; Analgesics; Animals; Carnosine; Formaldehyde; Gene Expression Regulation; Inflammation; | 2012 |
Antiinflammatory, analgesic and antioxidant activities of Cyathula prostrata (Linn.) Blume (Amaranthaceae).
Topics: Acetic Acid; Amaranthaceae; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic | 2012 |
The anti-inflammatory and antinociceptive properties of the chloroform fraction from Phyllanthus niruri plant is mediated via the peripheral nervous system.
Topics: Acetic Acid; Albumins; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Aspirin; Behavio | 2010 |
Anti-inflammatory and analgesic potential of a novel steroidal derivative from Bryophyllum pinnatum.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Diclofena | 2012 |
Enhancement of anti-inflammatory and antinociceptive actions of red ginseng extract by fermentation.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; | 2012 |
Isolation and biological activity of triglycerides of the fermented mushroom of Coprinus Comatus.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Biological | 2012 |
Antipyretic, analgesic and anti-inflammatory activity of Viola betonicifolia whole plant.
Topics: Acetaminophen; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Behavior, A | 2012 |
Kaurenoic acid from Sphagneticola trilobata Inhibits Inflammatory Pain: effect on cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway.
Topics: Acetic Acid; Administration, Oral; Animals; Asteraceae; Carbazoles; Cyclic GMP-Dependent Protein Kin | 2012 |
Bioactivity guided isolation of analgesic and anti-inflammatory constituents of Cnestis ferruginea Vahl ex DC (Connaraceae) root.
Topics: Acetic Acid; Africa; Analgesics; Animals; Anti-Inflammatory Agents; Biflavonoids; Carrageenan; Conna | 2012 |
Anti-nociceptive and anti-inflammatory effects of Croton crassifolius ethanol extract.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Capillaries; Carrageen | 2012 |
Evaluation of analgesic and anti-inflammatory effects of ethanol extract of Ficus iteophylla leaves in rodents.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Ethanol; Ficus; Infl | 2011 |
Analgesic and anti-inflammatory activities of the methanol extract of Elaeagnus oldhamii Maxim. in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Carragee | 2012 |
Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier.
Topics: Acetic Acid; Amidohydrolases; Analgesics; Animals; Arachidonic Acids; ATP Binding Cassette Transport | 2012 |
Anti-inflammatory and analgesic properties of the ethanolic extract of Cnidoscolus aconitifolius in rats and mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Disease M | 2011 |
Anti-inflammatory effects of oleanolic acid on LPS-induced inflammation in vitro and in vivo.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carboxymethylcellulose Sodium; Cell A | 2013 |
Geopropolis from Melipona scutellaris decreases the mechanical inflammatory hypernociception by inhibiting the production of IL-1β and TNF-α.
Topics: Acetic Acid; Analgesics; Animals; Bees; Behavior, Animal; Brazil; Carrageenan; Complex Mixtures; For | 2012 |
Purification and biological activities of Abelmoschus esculentus seed lectin.
Topics: Abelmoschus; Acetic Acid; Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents; Carbo | 2012 |
Anti-inflammatory, analgesic, and antioxidant activities of Pisonia aculeata: folk medicinal use to scientific approach.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Carr | 2013 |
Effect of methanol extract from flower petals of Tagetes patula L. on acute and chronic inflammation model.
Topics: Acetic Acid; Acute Disease; Alprostadil; Animals; Bradykinin; Capillary Permeability; Carrageenan; C | 2002 |
Analgesic and antiinflammatory properties of Sideritis lotsyi var. Mascaensis.
Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Ba | 2002 |
A new bioactive steroidal saponin from Sansevieria cylindrica.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Perme | 2003 |
The analgesic, antipyretic and anti-inflammatory activity of Diospyros variegata Kruz.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-St | 2003 |
Anti-nociceptive and anti-inflammatory effects of methanolic extract of Asparagus pubescens root in rodents.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Behavior | 2003 |
Acetic acid conditioning stimulus induces long-lasting antinociception of somatic inflammatory pain.
Topics: Acetic Acid; Analgesics; Animals; Conditioning, Psychological; Inflammation; Male; Mice; Mice, Inbre | 2003 |
Antinociceptive, antiinflammatory and acute toxicity effects of Salvia leriifolia Benth seed extract in mice and rats.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationshi | 2003 |
Differential patterns of c-fos mRNA expression in the amygdaloid nuclei induced by chemical somatic and visceral noxious stimuli in rats.
Topics: Acetic Acid; Amygdala; Animals; Formaldehyde; In Situ Hybridization; Inflammation; Male; Pain; Pain | 2003 |
Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats.
Topics: Acetic Acid; Animals; Dinoprostone; Disease Models, Animal; Drug Administration Schedule; Fibrosis; | 2003 |
Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis.
Topics: Acetic Acid; Animals; Biomarkers; Colitis; Disease Models, Animal; Inflammation; Irritable Bowel Syn | 2003 |
The anti-inflammatory effect of leptin on experimental colitis: involvement of endogenous glucocorticoids.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis; Colon; Dehydration; Female; Glucocorticoids | 2004 |
Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1.
Topics: Acetic Acid; Animals; Arthritis, Experimental; Dinoprostone; Escherichia coli; Inflammation; Intramo | 2004 |
Antihyperalgesic effect of pentoxifylline on experimental inflammatory pain.
Topics: Acetic Acid; Animals; Arthritis, Experimental; Carrageenan; Hot Temperature; Hyperalgesia; Iloprost; | 2004 |
Analgesic and topical anti-inflammatory activity of Hypericum canariense L. and Hypericum glandulosum Ait.
Topics: Acetic Acid; Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-S | 2005 |
Oxytocin ameliorates oxidative colonic inflammation by a neutrophil-dependent mechanism.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colon; Female; Gastrointestinal Tract; Glutathione; Imm | 2005 |
Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes.
Topics: Acetic Acid; Animals; Colitis; Darkness; Ethanol; Female; Gastric Mucosa; Inflammation; Intestinal M | 2005 |
Differential effect of zileuton, a 5-lipoxygenase inhibitor, against nociceptive paradigms in mice and rats.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Capillary Permeability; Carrageenan; Cyclopropanes; Dose | 2005 |
Effect of adrenomedullin administration on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Adrenomedullin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Indicators a | 2005 |
Possible analgesic and anti-inflammatory interactions of aspartame with opioids and NSAIDs.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2005 |
Prevention of arthritic inflammation using an oriental herbal combination BDX-1 isolated from Achyranthes bidentata and Atractylodes japonica.
Topics: Acetic Acid; Achyranthes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; | 2005 |
Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Free Radicals; Gastric Mucosa; Glutathione Peroxid | 2005 |
Visceral, inflammatory and neuropathic pain in glycine receptor alpha 3-deficient mice.
Topics: Acetic Acid; Animals; Formaldehyde; Inflammation; Irritants; Mice; Mice, Mutant Strains; Neuralgia; | 2005 |
Gaultherin, a natural salicylate derivative from Gaultheria yunnanensis: towards a better non-steroidal anti-inflammatory drug.
Topics: Abdominal Pain; Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 2006 |
Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents.
Topics: Acetic Acid; Adrenergic Uptake Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavio | 2007 |
Prostaglandin facilitates afferent nerve activity via EP1 receptors during urinary bladder inflammation in rats.
Topics: Acetic Acid; Afferent Pathways; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bridged Bicyclo Co | 2006 |
Anti-inflammatory and anti-nociceptive activity of risedronate in experimental pain models in rats and mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Diphosphonates; | 2006 |
Analgesic, antiinflammatory, and ulcerogenic studies of meloxicam solid dispersion prepared with polyethylene glycol 6000.
Topics: Abdominal Pain; Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 2006 |
Antiinflammatory and analgesic effects of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract in rats and mice.
Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Diclofenac; Female; | 2006 |
Evaluation of anti-inflammatory and analgesic activity of a new class of biphenyl analogs in animal models of inflammation.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; C-Rea | 2006 |
Suppressive effect of Withania somnifera root powder on experimental gouty arthritis: An in vivo and in vitro study.
Topics: Acetic Acid; Animals; Arthritis, Experimental; Arthritis, Gouty; Cell Line; Humans; Indomethacin; In | 2006 |
Anti-inflammatory action of phenolic compounds from Gastrodia elata root.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Benzyl Compounds; Carrageenan; Cyc | 2006 |
Analgesic and anti-inflammatory activities of aqueous extract from Glycine tomentella root in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Fabaceae; Formaldehy | 2007 |
Synthesis and biological evaluation of thieno[2,3-d]pyrimidine derivatives for anti-inflammatory, analgesic and ulcerogenic activity.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Disease Models, An | 2007 |
Ketorolac-dextran conjugates: synthesis, in vitro and in vivo evaluation.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Buffers; Carrag | 2007 |
Anti-inflammatory and anti-nociceptive activities of Fumaria indica whole plant extract in experimental animals.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cotto | 2007 |
Biological effects of a sulfated-polysaccharide isolated from the marine red algae Champia feldmannii.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticoagula | 2008 |
Lipid synthesis in macrophages during inflammation in vivo: effect of agonists of peroxisome proliferator activated receptors alpha and gamma and of retinoid X receptors.
Topics: Acetic Acid; Animals; Cholesterol; Cholesterol Esters; Fatty Acids; Inflammation; Lipids; Lipopolysa | 2008 |
Pharmacological studies on Indian black tea (leaf variety) in acute and chronic inflammatory conditions.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetic Acid; Acute Disease; Animals; A | 2008 |
Synthesis of new imidazolyl acetic acid derivatives with anti-inflammatory and analgesic activities.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, A | 2008 |
Gangliosides antinociceptive effects in rodents.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; | 1984 |
Effect of phorbol myristate acetate, a tumor-promoting agent, on the growth of Mycobacterium lepraemurium in the mouse footpad.
Topics: Acetates; Acetic Acid; Animals; Dexamethasone; Female; Hypersensitivity, Delayed; Indomethacin; Infl | 1983 |
Ethnopharmacology of bear gall bladder: I.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Bile; Bile Ac | 1995 |
A device for automatic measurement of writhing and its application to the assessment of analgesic agents.
Topics: Acetates; Acetic Acid; Aminopyrine; Analgesics; Animals; Behavior, Animal; Caffeine; Disease Models, | 1994 |
Antinociceptive and antipyretic effects of alkaloids extracted from the stem bark of Hunteria zeylanica.
Topics: Acetates; Acetic Acid; Administration, Oral; Alkaloids; Analgesics; Analgesics, Non-Narcotic; Animal | 1994 |
Anti-nociceptive effects of aconiti tuber and its alkaloids.
Topics: Acetates; Acetic Acid; Aconitine; Analgesics; Animals; Arthritis, Experimental; Cold Temperature; Di | 1994 |
Tachykininergic mediation of viscerosensitive responses to acute inflammation in rats: role of CGRP.
Topics: Abdominal Muscles; Acetic Acid; Acute Disease; Animals; Calcitonin Gene-Related Peptide; Gastric Emp | 1997 |
The anti-inflammatory effects of ketoprofen in animal experiments.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzenesulfonates; Bradykinin; Capill | 1997 |
Induction of plasma hepatocyte growth factor in acute colitis of mice.
Topics: Acetic Acid; Acute Disease; Administration, Rectal; Animals; Biomarkers; Colitis; Disease Models, An | 1997 |
Acute experimental colitis decreases colonic circular smooth muscle contractility in rats.
Topics: Acetic Acid; Acetylcholine; Acute Disease; Animals; Colitis; Colon; Gastrointestinal Motility; GTP-B | 1997 |
Inflammation modulates in vitro colonic myoelectric and contractile activity and interstitial cells of Cajal.
Topics: Acetic Acid; Animals; Colon; Dogs; Ethanol; In Vitro Techniques; Inflammation; Intestinal Mucosa; Me | 1997 |
Anti-P-selectin antibody exacerbated inflammatory responses in acetic acid-induced colitis.
Topics: Acetic Acid; Animals; Antibodies; Colitis; Colon; Immunoglobulin G; Inflammation; Male; Nitric Oxide | 1997 |
Suppression of inflammatory responses by surfactin, a selective inhibitor of platelet cytosolic phospholipase A2.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Bacterial Proteins; | 1998 |
Antinociceptive effect of meloxicam, in neurogenic and inflammatory nociceptive models in mice.
Topics: Abdominal Muscles; Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Capsaicin; Cyclooxygenase I | 1998 |
Studies on the anti-inflammatory and analgesic activity of Cedrus deodara (Roxb.) Loud. wood oil.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Ed | 1999 |
Altered pain responses in mice lacking alpha 1E subunit of the voltage-dependent Ca2+ channel.
Topics: Acetic Acid; Animals; Anxiety; Calcium; Calcium Channels, R-Type; Exploratory Behavior; Fear; Formal | 2000 |
Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene.
Topics: Acetic Acid; Animals; Behavior, Animal; Capsaicin; Colon; Cyclophosphamide; Cystitis; Female; Hypera | 2000 |
Cytokine-mediated inflammatory hyperalgesia limited by interleukin-1 receptor antagonist.
Topics: Acetic Acid; Animals; Antibodies; Bradykinin; Carrageenan; Cytokines; Dinoprostone; Dopamine; Dose-R | 2000 |
Kurosu, a traditional vinegar produced from unpolished rice, suppresses lipid peroxidation in vitro and in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetic Acid; Animals; Antioxidants; Bepridil; Biphenyl Compounds; | 2000 |
Altered neuroadaptation in opiate dependence and neurogenic inflammatory nociception in alpha CGRP-deficient mice.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; F | 2001 |
Tachykinin NK(2) receptors and enhancement of cholinergic transmission in the inflamed rat colon: an in vivo motility study.
Topics: Acetic Acid; Animals; Atropine; Cholinergic Fibers; Colon; Enzyme Inhibitors; Gastrointestinal Motil | 2001 |
Antinociceptive, anti-inflammatory and acute toxicity effects of Zhumeria majdae extracts in mice and rats.
Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Ag | 2002 |
Evaluation of the antinflammatory and analgesic activity of Sideritis canariensis var. pannosa in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Carrageenan; Chlo | 2002 |
Effects of ablation of N- and R-type Ca(2+) channels on pain transmission.
Topics: Acetic Acid; Animals; Behavior, Animal; Calcium Channels, N-Type; Calcium Channels, R-Type; Central | 2002 |
Parathyroid hormone fragment 1-34 inhibits drug-induced inflammation in various experimental models.
Topics: Acetates; Acetic Acid; Animals; Carrageenan; Edema; Inflammation; Male; Nystatin; Parathyroid Hormon | 1991 |
Analgesic and acute central nervous system side effects of the intravenously administered enkephalinase inhibitor SCH 32615.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Autonomic Nervous System; Behavior, Animal; Central Nerv | 1991 |
Pharmacological effects of SCH 30497--a novel analgesic substance.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nervous System; D | 1985 |
Characteristics of inflammation induced by fusarenon-X, a trichothecene mycotoxin from Fusarium species.
Topics: Abdomen; Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents; Capillary Permeability; Dose-Resp | 1987 |
Biosynthesis of paf-acether: VIII: Impairment of paf-acether production in activated macrophages does not depend upon acetyltransferase activity.
Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Acetyltransferases; Animals; Female; Glycerylphosphorylcho | 1986 |