acetic acid has been researched along with Gastric Ulcer in 370 studies
Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.
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" The anthocyanidin effects were examined in gastric ulcer mouse models induced by ethanol, non-steroidal anti-inflammatory drugs (NSAIDs), ischemia-reperfusion (IR), acetic acid and duodenal ulcer induced by polypharmacy." | 8.02 | Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation. ( Dos Santos, RC; Fagundes, FL; Pereira, QC; Zarricueta, ML, 2021) |
" speciosa accelerated healing of gastric ulcers even in presence of indomethacin, while decreasing bacterial loads in rats' stomachs." | 8.02 | Eremomastax speciosa (Hochst.) Cufod. counteracts the delaying effect of indomethacin on Helicobacter pylori-associated chronic gastric ulcers healing. ( Amang, AP; Choudhary, MI; Enow-Orock, GE; Maharjan, R; Mezui, C; Siwe, GT; Tan, PV; Zondegoumba, NE, 2021) |
" To elucidate the mechanism responsible for delayed healing of the gastric injury in old age, we analyzed the expression of these markers in rats of different months during the healing of an acetic acid-induced gastric ulcer." | 7.96 | Immunohistochemical Studies of Age-Related Changes in Cell Proliferation and Angiogenesis during the Healing of Acetic Acid-Induced Gastric Ulcers in Rats. ( Ajayi, AF; Olaleye, SB, 2020) |
" After the period of exposure, chronic gastric ulcer were induced by intraluminal application of 50% acetic acid." | 7.96 | Exposure to Mosquito Coil Smoke Delays Healing of Acetic Acid Induced Gastric Ulcer in Male Wistar Rats. ( Odukanmi, A; Olaleye, SB; Olanrewaju, TR; Salami, AT, 2020) |
" This study evaluated its healing efficacy and the mechanism involved using the rat model of chronic gastric ulcer induced by serosal injection of 80% acetic acid in vivo, and human gastric adenocarcinoma cells (AGS) in vitro." | 7.91 | (-)-Myrtenol accelerates healing of acetic acid-induced gastric ulcers in rats and in human gastric adenocarcinoma cells. ( Braga, AD; Lopes, MTP; Nunes, PIG; Oliveira, FTB; Oliveira, RCM; Rao, VS; Santos, FA; Santos, VG; Silva, ACA; Sousa, DP; Viana, AFSC; Viana, DA, 2019) |
"The gastroprotective property of (-)-myrtenol, a monoterpenoid, has been demonstrated previously against acute gastric ulceration induced by ethanol." | 7.91 | (-)-Myrtenol accelerates healing of acetic acid-induced gastric ulcers in rats and in human gastric adenocarcinoma cells. ( Braga, AD; Lopes, MTP; Nunes, PIG; Oliveira, FTB; Oliveira, RCM; Rao, VS; Santos, FA; Santos, VG; Silva, ACA; Sousa, DP; Viana, AFSC; Viana, DA, 2019) |
"This study was conducted to investigate the effects of nitric oxide (NO) in acetic acid-induced gastric ulcer of rats and the underlying mechanisms." | 7.85 | Nitric oxide donor protects against acetic acid-induced gastric ulcer in rats via S-nitrosylation of TRPV1 on vagus nerve. ( Gong, L; Han, T; Li, J; Liu, C; Tang, Y; Xue, B; Yu, X, 2017) |
"Carbon monoxide (CO), a gaseous mediator produced by haem oxygenases (HOs), has been shown to prevent stress-, ethanol-, aspirin- and alendronate-induced gastric damage; however, its role in gastric ulcer healing has not been fully elucidated." | 7.85 | Carbon monoxide released from its pharmacological donor, tricarbonyldichlororuthenium (II) dimer, accelerates the healing of pre-existing gastric ulcers. ( Brzozowski, T; Chmura, A; Ginter, G; Hubalewska-Mazgaj, M; Kwiecien, S; Magierowska, K; Magierowski, M; Pajdo, R; Sliwowski, Z, 2017) |
"The purpose of our investigative work has been to determine whether there can be therapeutic roles in the administration of sildenafil citrate, heparin and several neuropeptides on an animal model where gastric ulcers were induced with acetic acid, and to compare their efficacy." | 7.85 | Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017) |
"Overall the data indicate that low dose heparin, and especially sildenafil citrate and neuropeptides, can be used clinically as an alternative approach in the treatment of the gastric ulcer." | 7.85 | Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017) |
"In order to elucidate the contribution of cycloxygenase (COX) enzymes in the anti-oxidant and anti-inflammatory mechanisms of nesfatin-1, which improves the healing process of chronic gastric ulcers, either acetic acid (80%; ulcer groups; n = 40) or saline (control groups; n = 40) was applied to the serosal surface of male Sprague Dawley rats' stomachs for 1 min." | 7.85 | Anti-inflammatory effects of nesfatin-1 on acetic acid-induced gastric ulcer in rats: involvement of cyclo-oxygenase pathway. ( Cantali-Ozturk, C; Demirci, EK; Kolgazi, M; Ozdemir-Kumral, ZN; Sirvanci, S; Yegen, BC; Yuksel, M, 2017) |
" This study evaluated the mechanisms involved in the gastric ulcer healing of the hydroalcoholic extract from green tea (GEt), its ethyl acetate fraction, (GEAc) and epigallocatechin gallate (EGCG) using the model of acetic acid-induced gastric ulcer in rats." | 7.83 | Healing mechanisms of the hydroalcoholic extract and ethyl acetate fraction of green tea (Camellia sinensis (L.) Kuntze) on chronic gastric ulcers. ( Baggio, CH; Borato, DG; da Silva, LM; de Souza, LM; Iacomini, M; Maria-Ferreira, D; Scoparo, CT; Werner, MF, 2016) |
"This research was performed to explore the protective effect of cod skin collagen peptides (CCP) on gastric ulcer induced by acetic acid." | 7.83 | Protective Effect of Cod (Gadus macrocephalus) Skin Collagen Peptides on Acetic Acid-Induced Gastric Ulcer in Rats. ( Hou, H; Li, B; Niu, H; Wang, Z; Zhang, Z, 2016) |
"The model of gastric ulcer was imitated by acetic acid in rats, and AL was gavaged." | 7.81 | Comparison of the anti-ulcer activity between the crude and bran-processed Atractylodes lancea in the rat model of gastric ulcer induced by acetic acid. ( Cai, Q; Jia, TZ; Jiang, N; Ma, MY; Min, DY; Yu, Y; Yuan, Y, 2015) |
"Gastric ulcers were induced by the serosal application of 100% acetic acid, and the areas of the ulcers were measured thereafter." | 7.79 | NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4(+)VEGFR1(+) cells to the ulcer granulation tissues. ( Ae, T; Amano, H; Eshima, K; Hosono, K; Ito, Y; Katada, C; Koizumi, W; Majima, M; Minamino, T; Ohno, T; Sato, T; Shibuya, M; Suzuki, T, 2013) |
"The effect of fumonisin B1, an inhibitor of ceramide synthase, and of d,l,-threo-1-phenyl-2-hexadecanoylamino-3-morpholino-1-propanol (PPMP) and N-butyldeoxynojirimycin (NB-DNJ), both inhibitors of glucosylceramide synthase, on the accumulation of ceramide and formation of gastric ulcer were examined in the rat model of acetic acid-induced gastric ulcer." | 7.79 | Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. ( Hibi, T; Miura, S; Mizushima, T; Nagata, H; Nakashita, M; Suzuki, H; Taki, T; Uehara, K, 2013) |
"Fumonisin B1 attenuated acetic acid-induced gastric ulcer formation, associated with a decrease in the number of apoptotic cells." | 7.79 | Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. ( Hibi, T; Miura, S; Mizushima, T; Nagata, H; Nakashita, M; Suzuki, H; Taki, T; Uehara, K, 2013) |
"We evaluate the curative efficacy of the ethanolic extract (EET) of roots from Arctium lappa (bardana) in healing of chronic gastric ulcers induced by 80% acetic acid in rats and additionally studies the possible mechanisms underlying this action." | 7.79 | Ethanolic extract of roots from Arctium lappa L. accelerates the healing of acetic acid-induced gastric ulcer in rats: Involvement of the antioxidant system. ( Allemand, A; André, E; Baggio, CH; Cipriani, TR; da Silva, LM; Dartora, N; de Souza, LM; Dos Santos, AC; Marques, MC; Mendes, DA; Werner, MF, 2013) |
"To observe the effects and mechanisms of Pongamia pinnata root flavonoids (PRF) on the experimental gastric ulcer induced by acetic acid and to study the mechanism of PRF on the quality of ulcer healing." | 7.78 | [Effect of Pongamia pinnata root flavonoids on the quality of ulcer healing and expression of EGF and TGF-alpha in the rat model of gastric ulcer induced by acetic acid]. ( Huang, XZ; Liu, KY; Zhu, Y, 2012) |
"The models were established by acetic acid erosion, the quality of ulcer healing of PRF on the model of gastric ulcer were observed." | 7.78 | [Effect of Pongamia pinnata root flavonoids on the quality of ulcer healing and expression of EGF and TGF-alpha in the rat model of gastric ulcer induced by acetic acid]. ( Huang, XZ; Liu, KY; Zhu, Y, 2012) |
" The pharmacological activity of AFE and pure scopoletin at the same equivalent dose present in AFE was investigated in rat on gastro-esophageal inflammatory models (acid reflux esophagitis, acute gastritis induced by ethanol and serotonin, and chronic gastric ulcer induced by acetic acid); gastric biochemical parameters and gastrointestinal motility." | 7.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
"50 g/kg) significantly prevented the formation of acid reflux esophagitis, reduced the formation of ethanol-induced acute gastric lesions, suppressed the development of gastric lesions in response to serotonin, and accelerated the healing of acetic acid-induced chronic gastric ulcer in rats with equal potency to those obtained by standard antisecretory agents (ranitidine and lansoprazole)." | 7.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
" (Rubiaceae) fruit, commonly known as "Noni", in an aqueous extract preparation (AFE) as used in Thai traditional medicine and its biomarker scopoletin on gastro-esophageal inflammatory models that are related to the claimed pharmacological properties of AFE and/or resembled the human esophagitis or gastric ulcer." | 7.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
" This study aimed to determine the role of viable Lactobacillus in the healing of acetic acid-induced chronic gastric ulcer." | 7.76 | Yogurt containing Lactobacillus gasseri OLL 2716 (LG21 yogurt) accelerated the healing of acetic acid-induced gastric ulcer in rats. ( Kurakazu, K; Shimizu, K; Uchida, M, 2010) |
"To evaluate the role of ALA treatment on the healing of acetic acid-induced gastric ulcer, rats were given ALA (35 mg/kg/day) or saline for 3 days before the induction of ulcer and the treatment was continued twice daily for 2 days (early) or 10 days (late) until they were decapitated." | 7.75 | Alpha-lipoic acid improves acetic acid-induced gastric ulcer healing in rats. ( Ercan, F; Erzik, C; Karakoyun, B; Yeğen, BC; Yüksel, M, 2009) |
"This study is to investigate therapeutic effect of astaxanthin on acetic acid-induced gastric ulcer in rats." | 7.75 | [Therapeutic effect of astaxanthin on acetic acid-induced gastric ulcer in rats]. ( Fu, Y; Ruan, H; Yang, Q; Zhang, Z; Zhu, X, 2009) |
" Optimal effective dose of PPSM (25 mg/kg) showed antiulcerogenic activity against acute gastric ulcers (GU) induced by pylorus ligation and aspirin and duodenal ulcer induced by cysteamine but not against ethanol-induced GU." | 7.75 | Effect of methanolic extract of Pongamia pinnata Linn seed on gastro-duodenal ulceration and mucosal offensive and defensive factors in rats. ( Agarwal, PK; Dorababu, M; Goel, RK; Goel, S; Joshi, VK; Prabha, T; Singh, A, 2009) |
"In the present study, we compared the effects of alpha-tocopherol and probucol, antioxidants, on the healing of acetic acid-induced gastric ulcers in 8-, 48- and 96-week-old rats." | 7.74 | Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol. ( Ishihara, M; Ito, M; Kojima, R, 2008) |
" In the present study, we examined the effect of alendronate on the healing of acetic acid-induced gastric ulcers in rats and investigated the mechanism involved in this action both in vivo and in vitro using the rat gastric epithelial cell line (RGM1)." | 7.74 | Impairment of gastric ulcer healing by alendronate, a nitrogen-containing bisphosphonate, in rats. ( Aihara, E; Amagase, K; Hayashi, S; Nishikawa, K; Takeuchi, K, 2007) |
"Gastric ulcers were induced with acetic acid in rats; aspirin was administrated by gavage from day 25 to day 54 after ulcer induction." | 7.74 | Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007) |
"Aspirin enhance the recurrence of gastric ulcer." | 7.74 | Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007) |
"To assess the synergistic action of famotidine (FMD) and chlorpheniramine (CPA) on acetic acid-induced chronic gastric ulcer in rats." | 7.73 | Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats. ( Chen, C; Qin, Z, 2005) |
"The synergistic action of FMD and CPA on acetic acid-induced chronic gastric ulcer in rats decreases the incidence of ulcer and also enhances the healing of ulcer." | 7.73 | Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats. ( Chen, C; Qin, Z, 2005) |
" Since prostaglandins are inducers of hepatocyte growth factor (HGF), we examined the effect of rebamipide on the expression of HGF, c-met, cyclooxygenase-2 (Cox-2) and subtype of the prostaglandin E2 receptor (EP2) in acetic acid-induced gastric ulcer, a model of human ulcer." | 7.72 | Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor. ( Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A, 2003) |
" Gastric ulcers were produced by injecting 50 microl of 20% acetic acid into subserosa of the border between the fundic and antral gland areas." | 7.72 | Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor. ( Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A, 2003) |
"We previously discovered that a 4-wk course of indomethacin delivered to rats with acetic acid ulcers resulted in production of "unhealed gastric ulcers" that persisted for up to 12 wks after treatment cessation." | 7.72 | Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats. ( Amagase, K; Okabe, S; Tsukimi, Y; Yokota, M, 2003) |
" We investigated the changes in the level of gastric colonization 140 days after inducing gastric ulcer by acetic acid in the antral mucosa of a miniature pig infected with H." | 7.72 | Temporal increase in the gastric colonization of Helicobacter pylori after healing of acetic acid-induced gastric ulcer in a miniature pig. ( Iwata, M; Katsuta, M; Kikuchi, I; Koga, T; Okazaki, Y; Sato, K; Shimada, Y; Takahashi, K, 2003) |
"In this study, the healing effects of Centella asiatica water extract (CE) and asiaticoside (AC), an active constituent of CE, on acetic acid induced gastric ulcers (kissing ulcers) in rats were examined." | 7.72 | The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats. ( Cheng, CL; Guo, JS; Koo, MW; Luk, J, 2004) |
"The purpose of this study was to evaluate the healing effect of interleukin-11 (IL-11) on acetic acid-induced gastric ulcer in rats." | 7.71 | Mechanism of the antiulcerogenic effect of IL-11 on acetic acid-induced gastric ulcer in rats. ( Fukuda, E; Ito, M; Matsuu, M; Nakashima, M; Nakayama, T; Sekine, I; Shichijo, K; Wen, CY, 2002) |
"Acetic acid was perfused into the gastric cavitties of 130 rats to produce animal model of /gastric ulcer." | 7.71 | [Expression and activity of cyclooxygenases-1 and -2 in acetic acid induced gastric ulcer in rats]. ( Guo, J; Koo, MW; Wang, J, 2001) |
"To investigate the effect of Jianpiyiqi prescription on the expression of heat shock proteins (HSPs) and the changes of HSPs in gastric-ulcerated rats, the rat model of chronic gastric ulcer was induced by acetic acid." | 7.71 | Effect of jianpiyiqi prescription on the expression of heat shock proteins in acetic acid-induced chronic gastric ulcer rats. ( Li, G; Luo, S; Tao, X, 2001) |
"To investigate the possible role of cyclooxygenase-2 (COX-2) inhibitor NS-398 in formation and healing of acetic acid-induced gastric ulcer in rats." | 7.71 | [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001) |
"Fourty eight male Sprague-Dawley rats weighed 160-180 g were perfused with acetic acid into the stomach to induce gastric ulcer and then divided into two groups." | 7.71 | [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001) |
"NS-398 inhibits COX-2 activity, thus alleviating inflammatory reaction in acetic acid induced gastric ulcer and averting further damage of tissues." | 7.71 | [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001) |
" A mechanistic study of the potentiating effects of cigarette smoking on acetic acid-induced gastric ulceration in rats was hence performed." | 7.70 | Mechanistic study of adverse actions of cigarette smoke exposure on acetic acid-induced gastric ulceration in rats. ( Cho, CH; Chow, JY; Ma, L, 1998) |
"Based on our previous studies that aspirin (ASA) -induced gastric ulceration in rats can be significantly reduced if the drug is chemically associated with phosphatidylcholine (PC), we undertook the present study to compare gastric ulcer healing rates in rats administered either unmodified or PC-complexed ASA." | 7.70 | Phosphatidylcholine-associated aspirin accelerates healing of gastric ulcers in rats. ( Kurinets, A; Lichtenberger, LM, 1998) |
"Effect of lafutidine ((+/-)-2-(furfurylsulfinyl)-N-[4-[4-(piperidinomethyl)-2-pyr idyl] oxy-(Z)-2-butenyl] acetamide, FRG-8813), a novel antiulcer agent, on the healing and relapse in acetic acid-induced gastric ulcer in rats was investigated." | 7.70 | [Effect of lafutidine, a novel antiulcer agent, on healing and relapse of acetic acid-induced gastric ulcer in rats]. ( Aoyama, M; Arai, Y; Ohnishi, H; Onodera, S; Shibata, M; Tanaka, M; Yamaura, T, 1998) |
" at an effective anti-inflammatory dose to rats with pre-existing acetic acid-induced gastric ulcer, NS-398 caused a statistically significant delay of ulcer healing." | 7.70 | Effects of novel anti-inflammatory compounds on healing of acetic acid-induced gastric ulcer in rats. ( Dyer, RD; Gilbertsen, RB; Guglietta, A; Kraus, ER; Lesch, CA; Sanchez, B; Schrier, D; Song, Y, 1998) |
"To investigate whether or not heparin can accelerate the healing process of acetic acid-induced gastric ulcers in rats and to identify the mechanisms for heparin to produce this effect, so that we can develop a new therapeutic application to heparin besides its traditional anticoagulant activity." | 7.70 | Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998) |
"Male Sprague-Dawley rats were used to produce acetic acid-induced gastric ulcers." | 7.70 | Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998) |
"Heparin with the doses used in the present study accelerated the healing of acetic acid-induced gastric ulcers in rats in a dose- and time-dependent manner, and this action was related to its effects to increase the levels of gastric mucosal PGE2 and GMBF as well as to decrease the gastric mucosal MPO activity." | 7.70 | Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998) |
"The healing of experimental gastric ulcers induced in rats is consistently delayed upon chronic treatment with indomethacin." | 7.70 | A new ulcer model, "unhealed gastric ulcers", induced by chronic treatment with indomethacin in rats with acetic acid ulcers. ( Amagase, K; Okabe, S, 1999) |
" The pharmacokinetics of the drug were also evaluated after oral administration to rats with acetic acid-induced gastric ulcer (AIURs)." | 7.70 | Gastrointestinal absorption of a new reversible proton pump inhibitor, YJA-20379-8, and its pharmacokinetics after oral administration in acetic acid-induced gastric ulcer in rats. ( Chang, MS; Chung, SY; Han, KS; Kim, HJ; Kim, J; Lee, MG, 1999) |
" In this study, we examined the effect of pentoxifylline on healing of acetic acid induced gastric ulcers in rats." | 7.70 | Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000) |
"Pentoxifylline accelerates healing of acetic acid induced gastric ulcer in rats." | 7.70 | Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000) |
"Rats with gastric ulcer received an intraperitoneal injection of 10 mg/kg pentoxifylline once daily for 14 days or for only the first 7 days or the last 7 days of the 14-day treatment period." | 7.70 | Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000) |
"To investigate the influence of water extracts of CagA-positive or -negative Helicobacter pylori on healing of chronic gastric ulcers and on connexin formation, proliferation and apoptosis, in acetic acid-induced chronic gastric ulcers in rats." | 7.70 | The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000) |
"Acetic acid was used to induce chronic gastric ulcers in rats, and a water extract of H." | 7.70 | The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000) |
"In untreated rats, acetic acid-induced gastric ulcers healed after 14 days and the electrophoretic band corresponding to connexin 32 appeared 4 days after ulcer induction." | 7.70 | The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000) |
"Effects of treatment with free radical scavengers in the healing process of acetic acid-induced gastric ulcer on the ulcer aggravation induced by indomethacin were investigated." | 7.69 | Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats. ( Kondo, M; Matsuyama, K; Naito, Y; Nishimura, S; Yagi, N; Yoshikawa, T, 1995) |
"This study was done to elucidate whether rebamipide during the initial period of acetic acid-induced gastric ulcer affected healing and future ulcer relapse." | 7.69 | Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine. ( Arakawa, T; Fukuda, T; Kobayashi, K; Watanabe, T; Yamasaki, K, 1995) |
"Tobacco cigarette smoke attenuates injury-induced hyperemia, aggravates hypertonic saline-induced mucosal damage, inhibits ulcer margin hyperemia, and increases the size of the acetic acid-induced ulcer in the rat stomach." | 7.69 | Misoprostol reverses the inhibition of gastric hyperemia and aggravation of gastric damage by tobacco cigarette smoke in the rat. ( Iwata, F; Leung, FW, 1995) |
"The healing of acetic acid-induced gastric ulcer in rats and the effects of cimetidine and calcitonin were investigated with reference to the enzyme activity of both prolylhydroxylase and collagenase as related to histological findings." | 7.69 | Wound healing of acetic acid-induced gastric ulcer in rats and the effects of cimetidine and calcitonin, with special reference to prolylhydroxylase and collagenase enzyme activity. ( Arai, M; Komatsu, H; Kurose, I; Maruyama, K; Nakamura, M; Okazaki, I; Tsuchiya, M, 1995) |
"The effects of IGN-2098 on the healing process of acetic acid-induced gastric ulcer was investigated in comparison with the other histamine H2-receptor antagonists, famotidine and roxatidine acetate HCl, in rats." | 7.69 | [Therapeutic effect of IGN-2098, a new antiulcer drug (H2-antagonist), in the ulcer diminishing period against acetic acid-induced gastric ulcer in rats]. ( Ikarashi, Y; Misaki, N; Ohba, S; Ohbayashi, S; Uchida, M, 1995) |
"The effects of cimetidine, omeprazole and atropine sulfate on the healing of acetic acid-induced gastric ulcers in rats with limited food intake time (9:00-10:00 a." | 7.69 | Effect of cimetidine and omeprazole on gastric ulcer healing of rats with limited food intake time. ( Ito, M; Kojima, R; Segami, T; Suzuki, Y; Tsukahara, T, 1994) |
"To investigate the effect of capsaicin, cimetidine, and in combination, given intragastrically in the healing of acetic acid induced chronic gastric ulcer in the rat." | 7.69 | Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996) |
"Capsaicin promotes the healing of acetic acid induced gastric ulcer, probably by its gastric hyperaemic effect." | 7.69 | Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996) |
"Capsaicin protects the gastric mucosa against experimental injury while capsaicin desensitisation reduces the rate of gastric ulcer healing." | 7.69 | Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996) |
"To clarify the relationship between Helicobacter pylori and the healing of gastric ulcers, we investigated the healing of acetic acid-induced gastric ulcers in the antral mucosa of Japanese monkeys (n = 5) infected with H." | 7.69 | Helicobacter pylori infection delays the healing of acetic acid-induced gastric ulcer in Japanese monkeys. ( Fujioka, T; Kodama, R; Kubota, T; Nasu, M; Shuto, R, 1996) |
"We found indomethacin aggravates healed gastric ulcers (ulcer relapse) in rats." | 7.69 | Prevention of gastric ulcer relapse induced by indomethacin in rats by a mutein of basic fibroblast growth factor. ( Asano, S; Inada, I; Maeda, R; Murakami, I; Sato, F; Satoh, H; Shino, A, 1997) |
" Therefore, the aim of this study was to examine the role of collagenase and gelatinases A and B in the development and healing of acetic acid-induced gastric ulcer in rats." | 7.69 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
"Gastric ulcer was induced by injecting 20 microliters glacial acetic acid into gastric wall of rat stomachs." | 7.69 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
"This study examined the relationship between healing of acetic acid-induced chronic gastric ulcer and connexin formation." | 7.69 | Relationship between healing of acetic acid-induced chronic gastric ulcer and connexin. ( Fujita, T; Kushima, R; Mine, T, 1997) |
" We investigated proliferative activity in the healing process of acetic acid-induced gastric ulcer by immunohistochemical staining of PCNA and 5-bromo-2-deoxyuridine (BrdU), and the two methods were compared." | 7.68 | Cell proliferation kinetics in acetic acid-induced gastric ulcer evaluated by immunohistochemical staining of proliferating cell nuclear antigen. ( Hiramatsu, A; Inoue, K; Kitajima, T; Mizuno, T; Nakano, T; Okuhira, M; Tani, K, 1993) |
"Effects of troxipide (Ku-54) on various experimental gastric ulcers in rats were studied." | 7.68 | [The pharmacodynamics of troxipide on experimental gastric ulcers in rats]. ( Fan, A; Fang, Z; Wang, J; Wang, Y; Zhang, L, 1993) |
"To clarify the ability of endoscopic ultrasonography (EUS) to diagnose gastric ulcer, we induced gastric ulcer (19 open ulcers and 11 ulcer scars) by injecting acetic acid into the stomach via an endoscope in 15 dogs." | 7.68 | Evaluation of acetic acid-induced gastric ulcers in dogs by endoscopic ultrasonography. ( Chijiiwa, Y; Fujishima, H; Maruoka, A; Misawa, T; Nawata, H, 1993) |
"We examined the effect of NC-1300-O-3 on the healing of acetic acid-induced gastric ulcers in male Donryu rats." | 7.68 | Effect of NC-1300-O-3 on healing of acetic acid-induced gastric ulcers in rats. ( Inoue, K; Okabe, S; Takagi, K, 1993) |
"Repeated administration of indomethacin delays the healing of acetic acid-induced gastric ulcers in rats, but the underlying mechanism remains unclear." | 7.68 | Mechanism by which indomethacin delays gastric ulcer healing in the rat: inhibited contraction of the ulcer base. ( Ogihara, Y; Okabe, S, 1993) |
"Repeated administration of indomethacin or prednisolone for 2 weeks apparently delayed the healing of initial gastric ulcers induced by acetic acid injection in rats." | 7.68 | Effects of indomethacin and prednisolone on the different stages of healing of acetic acid-induced gastric ulcers in the rat. ( Ogihara, Y; Okabe, S, 1993) |
"The effect of a proton pump inhibitor, omeprazole (OPZ), in combination with mouse epidermal growth factor (EGF), on the healing of chronic gastric ulcers induced by acetic acid in submandibular glands removed rats (SMR rat) was investigated." | 7.68 | [Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats]. ( Imai, S; Itoh, M; Joh, T; Takeuchi, T; Yokoyama, Y, 1992) |
"The localization of fibronectin (FN) and laminin (LM) and cellular kinetics of epithelium in acetic acid induced gastric ulcers were examined by immunohistochemistry, comparing fundic glands ulcer with fundic-pyloric border ulcer." | 7.68 | [The immunohistochemical study on the recurrent mechanism of acetic acid induced gastric ulcer in rats--extracellular matrix and cellular kinetics]. ( Yagi, K, 1992) |
"We investigated the effects of cimetidine and omeprazole on angiogenesis in granulation tissue and on the healing of gastric ulcers induced by acetic acid in rats." | 7.68 | Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats. ( Goto, H; Hase, S; Segawa, K; Tsuchida, T; Tsukamoto, Y, 1990) |
"To clarify the mechanism of gastric ulcer recurrence, we studied acetic acid-induced gastric ulcers." | 7.68 | Evaluation of acetic acid-induced gastric ulcers in rats by scanning acoustic microscopy. ( Goto, H; Hase, S; Mizutani, K; Niwa, Y; Ohashi, S; Tsukamoto, Y, 1991) |
"The macroscopic and microscopic effects of 12-sulfodehydroabietic acid monosodium salt (TA-2711, CAS 86408-72-2) on the healing of acetic acid-induced gastric ulcers in rats were compared with those of sucralfate and carbenoxolone." | 7.68 | Effects of the new anti-ulcer agent 12-sulfodehydroabietic acid monosodium salt on healing of acetic acid-induced gastric ulcers in rats. ( Iwasaki, H; Magaribuchi, T; Onoda, Y; Tamaki, H, 1991) |
"Repeated administration of indomethacin markedly delays spontaneous healing of experimental gastric ulcers induced in rats." | 7.68 | Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats. ( Hirose, H; Okabe, S; Takeuchi, K, 1991) |
"The present study was designed to investigate the changes in gastric mucosal PGI2 level accompanying the healing of acetic acid-induced gastric ulcers in rats." | 7.68 | Healing of acetic acid-induced gastric ulcer and gastric mucosal PGI2 level in rats. ( Irino, O; Kawano, O; Misaki, N; Saitoh, K; Uchida, M, 1990) |
"The present study examined the time sequence and histologic and ultrastructural features of the formation and evolution of experimental, acetic acid-induced gastric ulcerations in rats." | 7.68 | Vascular and microvascular changes--key factors in the development of acetic acid-induced gastric ulcers in rats. ( Dabros, W; Eltorai, M; Gergely, H; Hollander, D; Krause, WJ; Stachura, J; Tarnawski, A, 1990) |
"Epidermal growth factor (EGF) has been shown to enhance healing of experimental gastric ulcers when given subcutaneously or orally in the drinking water." | 7.68 | Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat. ( Endoh, K; Imai, S; Itoh, M; Iwai, A; Joh, T; Kawai, T; Matsusako, K; Takeuchi, T; Yasue, N; Yokoyama, Y, 1990) |
"Omeprazole, a gastric mucosal proton pump inhibitor, significantly and dose-dependently prevented the delayed healing of acetic acid-induced gastric ulcers in response to repeatedly administered indomethacin to rats." | 7.68 | Effect of omeprazole on delayed healing of acetic acid-induced gastric ulcers in rats. ( Nagai, H; Okabe, S; Wang, JY, 1990) |
"The anti-ulcer effect of sofalcone, an isoprenyl chalcone derivative, on acetic acid-induced gastric ulcers in rats was studied histologically and histochemically." | 7.67 | Effect of 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy) chalcone (sofalcone) on chronic gastric ulcers in rats. ( Arai, I; Kimura, M; Nakane, S; Saziki, R; Tarumoto, Y, 1984) |
"The progress of acetic acid-induced gastric ulcers in rats were sequentially observed with an endoscope for 365 days, and the influences of the ulcer-induced site, age and sex on the healing, recurrence and relapse of these ulcers were investigated." | 7.67 | [Experimental studies on gastric ulcer (6). Endoscopical evaluation of healing processes of acetic acid ulcer in rats (2): Healing, recurrence and relapse of ulcer]. ( Fukawa, K; Irino, O; Kawano, O; Misaki, N; Uchida, M, 1984) |
"In an attempt to elucidate the role of granulation vessels in the healing of gastric ulcer, healing and angiogenesis in granulation tissue of acetic acid ulcers were studied in rats." | 7.67 | Effects of prednisolone and human epidermal growth factor on angiogenesis in granulation tissue of gastric ulcer induced by acetic acid. ( Hase, S; Nakazawa, S; Segawa, K; Tsukamoto, Y, 1989) |
"The present study was undertaken to elucidate the role of mucous secreting cells in the healing of acetic acid-induced gastric ulcers in rats." | 7.67 | Physiological significance of mucous neck cell-type mucins in the healing of acetic acid-induced gastric ulcers in rats. ( Hashikura, Y; Ichikawa, H; Katsuyama, T; Kobayashi, C; Sugiyama, A, 1989) |
"We examined the changes in prolylhydroxylase (PH) and interstitial collagenase (CA) activities in the healing of acetic acid-induced gastric ulcers in rats." | 7.67 | Prolylhydroxylase and collagenase activities in the healing of acetic acid-induced gastric ulcers in rats and the effects of cimetidine and elcatonin. ( Komatsu, K; Kurose, I; Maruyama, K; Oda, M; Okazaki, I; Tsuchiya, M, 1989) |
"We investigated the roles of endogenous leukotrienes (LTs) and prostaglandins (PGs) in the healing of gastric ulcers induced by acetic acid in rats." | 7.67 | Roles of endogenous leukotrienes and prostaglandins in the healing of gastric ulcers induced by acetic acid in rats. ( Arakawa, T; Fukuda, T; Kobayashi, K; Nakamura, H; Nebiki, H; Torii, Y, 1989) |
"Changes in the pH gradient and thickness of the mucus gel layer in the healing of acetic acid-induced gastric ulcers in rats were investigated." | 7.67 | Role of the mucus gel layer in the healing of acetic acid-induced gastric ulcers in rats. ( Kawano, O; Matsueda, K; Misaki, N; Muraoka, A; Uchida, M; Umeda, N, 1989) |
"We examined the effect of human epidermal growth factor (hEGF) on the healing rate of gastric ulcers induced in rats." | 7.67 | Effects of human epidermal growth factor on natural and delayed healing of acetic acid-induced gastric ulcers in rats. ( Kuwahara, Y; Okabe, S, 1989) |
"We examined the mechanism by which repeated administration of indomethacin significantly delays the natural healing of experimental gastric ulcers induced in rats." | 7.67 | Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin. ( Okabe, S; Takeuchi, K; Wang, JY; Yamasaki, S, 1989) |
"A metalloproteinase was extracted from a medium of cultured gastric tissues following acetic acid-induced ulcer or taurocholic acid-induced gastritis, and the enzyme was partially purified by Sephadex G-200 column chromatography." | 7.67 | Production of metalloproteinase in gastric tissue with acetic acid-induced ulcer or taurocholic acid-induced gastritis. ( Ishikura, Y; Mori, Y; Murakami, S; Nakanishi, J; Tsuchiya, S, 1987) |
"Chronic gastric ulcers were produced by injection of 20% acetic acid (0." | 7.67 | Effects of trimoprostil on healing and recurrence of acetic acid-induced gastric ulcer in rats. ( Nakamura, K; Umeda, Y, 1986) |
"Ulcers were induced by serosal application of 80 % acetic acid to the stomach of rats anaesthetized with 50 mg/kg thiopentone sodium and treatment was given three times daily." | 5.46 | Effects of quinine on gastric ulcer healing in Wistar rats. ( Adeniyi, OS; Friday, ET; Makinde, OV; Olaleye, SB, 2017) |
"Gastric ulcers was induced in the animals of 12 groups with one untreated group being left as the control (Group I - control; given normal saline (NS))." | 5.46 | Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017) |
"Gastric ulcers were induced by the serosal application of 100% acetic acid, and the areas of the ulcers were measured thereafter." | 5.39 | NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4(+)VEGFR1(+) cells to the ulcer granulation tissues. ( Ae, T; Amano, H; Eshima, K; Hosono, K; Ito, Y; Katada, C; Koizumi, W; Majima, M; Minamino, T; Ohno, T; Sato, T; Shibuya, M; Suzuki, T, 2013) |
"Aspirin enhance the recurrence of gastric ulcer." | 5.34 | Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007) |
"Ulcer recurrence and poor healing may be critically important to the development of serious gastrointestinal complications in patients with long-term non-steroid anti-inflammatory drugs (NSAIDs)." | 5.34 | Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007) |
"Gastric ulcers were induced with acetic acid in rats; aspirin was administrated by gavage from day 25 to day 54 after ulcer induction." | 5.34 | Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007) |
"Gastric ulcers were induced in male SD rats by serosal application of acetic acid for 60 sec." | 5.34 | Effect of dopamine on the healing of acetic acid-induced gastric ulcers in rats. ( Amagase, K; Nishikawa, K; Takeuchi, K, 2007) |
"Gastric ulcer is a source of visceral pain." | 5.33 | Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006) |
"Gastric ulcers were induced by luminal application of 60% acetic acid under surgical conditions." | 5.33 | Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006) |
"Gastric ulcers were produced by injecting 50 microl of 20% acetic acid into subserosa of the border between the fundic and antral gland areas." | 5.32 | Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor. ( Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A, 2003) |
"The gastric ulcer was induced endoscopically with 1 mL of 40% acetic acid 12 days after inoculation of H." | 5.32 | Temporal increase in the gastric colonization of Helicobacter pylori after healing of acetic acid-induced gastric ulcer in a miniature pig. ( Iwata, M; Katsuta, M; Kikuchi, I; Koga, T; Okazaki, Y; Sato, K; Shimada, Y; Takahashi, K, 2003) |
"Gastric ulcers were induced in male Wistar rats by applying acetic acid to the fundus of the stomach." | 5.31 | Mechanism of the antiulcerogenic effect of IL-11 on acetic acid-induced gastric ulcer in rats. ( Fukuda, E; Ito, M; Matsuu, M; Nakashima, M; Nakayama, T; Sekine, I; Shichijo, K; Wen, CY, 2002) |
"Acetic acid was perfused into the gastric cavitties of 130 rats to produce animal model of /gastric ulcer." | 5.31 | [Expression and activity of cyclooxygenases-1 and -2 in acetic acid induced gastric ulcer in rats]. ( Guo, J; Koo, MW; Wang, J, 2001) |
"Pentoxifylline has many anti-inflammatory properties including inhibition of production of tumor necrosis factor alpha (TNF-alpha)." | 5.31 | Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000) |
"In untreated rats, acetic acid-induced gastric ulcers healed after 14 days and the electrophoretic band corresponding to connexin 32 appeared 4 days after ulcer induction." | 5.31 | The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000) |
"Acetic acid was used to induce chronic gastric ulcers in rats, and a water extract of H." | 5.31 | The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000) |
"In acetic acid-treated rats, this activity increased to 2." | 5.30 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
"Gastric ulcer was induced by injecting 20 microliters glacial acetic acid into gastric wall of rat stomachs." | 5.30 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
"Pretreatment with allopurinol (Allo, 5 mg/kg, i." | 5.30 | Mechanistic study of adverse actions of cigarette smoke exposure on acetic acid-induced gastric ulceration in rats. ( Cho, CH; Chow, JY; Ma, L, 1998) |
"Gastric ulcers were induced in anesthetized rats by briefly exposing the mucosal surface to 0." | 5.30 | Phosphatidylcholine-associated aspirin accelerates healing of gastric ulcers in rats. ( Kurinets, A; Lichtenberger, LM, 1998) |
" Heparin in the doses of 100, 500, and 1000 U/kg were administered intravenously through the tail vein once daily, starting 1 day after ulcer induction for 7 days in the dose-response experiment or heparin 1000 U/kg at a time schedule of 3, 5, and 7 days in the time-response study, respectively." | 5.30 | Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998) |
" The results suggest that modification of the oral dose of YJA-20379-8 may not be required in gastric ulcer patients if the present rat pharmacokinetic data could be extrapolated to man." | 5.30 | Gastrointestinal absorption of a new reversible proton pump inhibitor, YJA-20379-8, and its pharmacokinetics after oral administration in acetic acid-induced gastric ulcer in rats. ( Chang, MS; Chung, SY; Han, KS; Kim, HJ; Kim, J; Lee, MG, 1999) |
"Gastric ulcers were produced on the anterior wall of the stomach of male Sprague-Dawley rats by submucosal injection of 20% acetic acid." | 5.29 | Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats. ( Kondo, M; Matsuyama, K; Naito, Y; Nishimura, S; Yagi, N; Yoshikawa, T, 1995) |
"Gastric ulcers were produced 5 days after submucosal injection of 20% acetic acid (0." | 5.29 | Effect and mechanism of sucralfate on healing of acetic acid-induced gastric ulcers in rats. ( Ogihara, Y; Okabe, S, 1993) |
"The influence of KU-1257 on the recurrence and relapse of acetic acid ulcers in rats was investigated grossly and histologically in comparison with that of cimetidine." | 5.29 | [Influence of KU-1257 on the recurrence and relapse of acetic acid-induced chronic gastric ulcers in rats]. ( Kobayashi, F; Ohkubo, H; Ohsawa, A; Sekiguchi, H; Taga, F, 1996) |
"The effect of a proton pump inhibitor, omeprazole (OPZ), in combination with mouse epidermal growth factor (EGF), on the healing of chronic gastric ulcers induced by acetic acid in submandibular glands removed rats (SMR rat) was investigated." | 5.28 | [Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats]. ( Imai, S; Itoh, M; Joh, T; Takeuchi, T; Yokoyama, Y, 1992) |
" Chronic administration of hydrocortisone sodium phosphate resulted in a significant delay of ulcer healing induced by acetic acid." | 5.28 | Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991) |
"Chronic gastric ulcers were produced in male Wistar rats, weighing 180 g, by the application of 100% acetic acid." | 5.28 | Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991) |
"Gastric ulcers were induced 5 days after submucosal injection of an acetic acid solution into the stomachs of rats." | 5.28 | Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats. ( Hirose, H; Okabe, S; Takeuchi, K, 1991) |
" This suggests that further stimulation of ulcer healing may be expected if EGF is given with an acid-suppressive agent or with an agent allowing EGF to remain in rat gastric lumen at high concentrations." | 5.28 | Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat. ( Endoh, K; Imai, S; Itoh, M; Iwai, A; Joh, T; Kawai, T; Matsusako, K; Takeuchi, T; Yasue, N; Yokoyama, Y, 1990) |
"Gastric ulcers were induced by subserosal injection of acetic acid, and confirmed by endoscopy on the third day." | 5.28 | Prolylhydroxylase and collagenase activities in the healing of acetic acid-induced gastric ulcers in rats and the effects of cimetidine and elcatonin. ( Komatsu, K; Kurose, I; Maruyama, K; Oda, M; Okazaki, I; Tsuchiya, M, 1989) |
"Gastric ulcers were produced 5 days after injecting 20% acetic acid (0." | 5.28 | Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin. ( Okabe, S; Takeuchi, K; Wang, JY; Yamasaki, S, 1989) |
"Chronic gastric ulcers were produced by injection of 20% acetic acid (0." | 5.27 | Effects of trimoprostil on healing and recurrence of acetic acid-induced gastric ulcer in rats. ( Nakamura, K; Umeda, Y, 1986) |
"The present study aimed to observe the healing effect of QWZT on acetic acid-induced gastric ulcer in a rat model and to preliminarily elucidate its possible therapeutic mechanism from the perspective of host intestinal microbiota and metabolism." | 4.84 | Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats. ( An, Y; Jiang, S; Lin, H; Liu, J; Wang, C; Wang, F; Wang, G; Zhang, J; Zheng, H; Zheng, W, 2024) |
"The Wistar male rats (7 weeks old; weight 180-200 g) were randomly divided into normal control group (NC), acetic acid-induced gastric ulcer group (GU), and QWZT treatment group (High dose: 1250 mg/kg/day, Middle dose: 625 mg/kg/day, Low dose: 312." | 4.84 | Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats. ( An, Y; Jiang, S; Lin, H; Liu, J; Wang, C; Wang, F; Wang, G; Zhang, J; Zheng, H; Zheng, W, 2024) |
" Apart from that, FMT improved acetic acid-induced gastric ulcers in rats." | 4.84 | Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats. ( An, Y; Jiang, S; Lin, H; Liu, J; Wang, C; Wang, F; Wang, G; Zhang, J; Zheng, H; Zheng, W, 2024) |
"QWZT improved acetic acid-induced gastric ulcers in rats by remodeling intestinal microbiota and regulating host metabolism." | 4.84 | Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats. ( An, Y; Jiang, S; Lin, H; Liu, J; Wang, C; Wang, F; Wang, G; Zhang, J; Zheng, H; Zheng, W, 2024) |
"Rats (females) were treated with AEC (3, 30 or 300 mg/kg) prior to the ethanol or piroxicam-induced gastric ulcers." | 4.12 | Gastroprotective and gastric healing effects of the aqueous extract of Casearia sylvestris in rodents: Ultrasound, histological and biochemical analyzes. ( Aires, BA; Boeing, T; Cury, BJ; da Costa Zanatta, ME; de Oliveira, BMM; Dos Santos, AC; Mota da Silva, L; Roman Junior, WA; Serpa, PZ; Somensi, LB; Steffler, AM; Venzon, L, 2022) |
"The AEC (30 or 300 mg/kg) prevented ulcers in the ethanol- and piroxicam-induced acute." | 4.12 | Gastroprotective and gastric healing effects of the aqueous extract of Casearia sylvestris in rodents: Ultrasound, histological and biochemical analyzes. ( Aires, BA; Boeing, T; Cury, BJ; da Costa Zanatta, ME; de Oliveira, BMM; Dos Santos, AC; Mota da Silva, L; Roman Junior, WA; Serpa, PZ; Somensi, LB; Steffler, AM; Venzon, L, 2022) |
"Gastric healing effects, underlining mechanisms, and behavioral changes were measured in80% acetic acid-induced gastric ulcer model in rats receiving GE by oral (30 mg/kg) or inhaled route (1 mg/L of air/min); whereas the effects of GE to avoid ulcer recurrence was evaluated in mice submitted to 10% acetic acid plus IL-1β ulcer." | 4.12 | Geraniol accelerates the gastric healing, minimizes ulcers recurrence, and reduces anxiolytic-like behavior in ulcerated rodents by oral or inhaled route. ( Boeing, T; Cazarin, CA; da Silva, LM; de Souza, MM; Dos Santos França, TC; Longo, B; Mariano, LNB; Mariott, M; Meurer, MC; Pereira, LN; Somensi, LB; Venzon, L, 2022) |
"Geraniol (GE) is dietary acyclic monoterpene alcohol found in essential oils from aromatic plants with therapeutic value against gastric ulcers already described." | 4.12 | Geraniol accelerates the gastric healing, minimizes ulcers recurrence, and reduces anxiolytic-like behavior in ulcerated rodents by oral or inhaled route. ( Boeing, T; Cazarin, CA; da Silva, LM; de Souza, MM; Dos Santos França, TC; Longo, B; Mariano, LNB; Mariott, M; Meurer, MC; Pereira, LN; Somensi, LB; Venzon, L, 2022) |
" The anthocyanidin effects were examined in gastric ulcer mouse models induced by ethanol, non-steroidal anti-inflammatory drugs (NSAIDs), ischemia-reperfusion (IR), acetic acid and duodenal ulcer induced by polypharmacy." | 4.02 | Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation. ( Dos Santos, RC; Fagundes, FL; Pereira, QC; Zarricueta, ML, 2021) |
" trimera (EOBT) against gastric ulcer lesions caused by absolute ethanol and acetic acid, respectively, and to identify the mechanism of action of this essential oil in male Wistar rats." | 4.02 | The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity. ( Assunção, R; Besten, MA; Bueno, G; Chavez Rico, SL; Emílio-Silva, MT; Heiden, G; Hiruma-Lima, CA; Justulin, LA; Lima Camargo, AC; Machado da Rocha, LR; Nunes, DS; Ohara, R; Périco, LL; Rodrigues, VP, 2021) |
" speciosa accelerated healing of gastric ulcers even in presence of indomethacin, while decreasing bacterial loads in rats' stomachs." | 4.02 | Eremomastax speciosa (Hochst.) Cufod. counteracts the delaying effect of indomethacin on Helicobacter pylori-associated chronic gastric ulcers healing. ( Amang, AP; Choudhary, MI; Enow-Orock, GE; Maharjan, R; Mezui, C; Siwe, GT; Tan, PV; Zondegoumba, NE, 2021) |
" Chronic gastric ulcer in rats was modeled using glacial acetic acid." | 3.96 | A new derivative of acetylsalicylic acid and carnosine: synthesis, physical and chemical properties, biological activity. ( Andreeva, LA; Fedorova, TN; Kulichenkova, KN; Kulikova, OI; Lopachev, AV; Lopacheva, OM; Migulin, VA; Nagaev, IY; Stvolinsky, SL; Trubitsina, IE, 2020) |
" To elucidate the mechanism responsible for delayed healing of the gastric injury in old age, we analyzed the expression of these markers in rats of different months during the healing of an acetic acid-induced gastric ulcer." | 3.96 | Immunohistochemical Studies of Age-Related Changes in Cell Proliferation and Angiogenesis during the Healing of Acetic Acid-Induced Gastric Ulcers in Rats. ( Ajayi, AF; Olaleye, SB, 2020) |
" After the period of exposure, chronic gastric ulcer were induced by intraluminal application of 50% acetic acid." | 3.96 | Exposure to Mosquito Coil Smoke Delays Healing of Acetic Acid Induced Gastric Ulcer in Male Wistar Rats. ( Odukanmi, A; Olaleye, SB; Olanrewaju, TR; Salami, AT, 2020) |
"We used acetic acid to induce gastric ulcer in Sprague Dawley rats." | 3.96 | Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157. ( Li, N; Lu, Q; Shi, R; Shrestha, SM; Tan, J; Wei, M; Wu, G; Wu, H; Zhang, Z, 2020) |
"Although Clopidogrel is safe in healthy volunteers, it can induce recurrence of gastric ulcers in high-risk patients." | 3.96 | Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157. ( Li, N; Lu, Q; Shi, R; Shrestha, SM; Tan, J; Wei, M; Wu, G; Wu, H; Zhang, Z, 2020) |
" This study evaluated its healing efficacy and the mechanism involved using the rat model of chronic gastric ulcer induced by serosal injection of 80% acetic acid in vivo, and human gastric adenocarcinoma cells (AGS) in vitro." | 3.91 | (-)-Myrtenol accelerates healing of acetic acid-induced gastric ulcers in rats and in human gastric adenocarcinoma cells. ( Braga, AD; Lopes, MTP; Nunes, PIG; Oliveira, FTB; Oliveira, RCM; Rao, VS; Santos, FA; Santos, VG; Silva, ACA; Sousa, DP; Viana, AFSC; Viana, DA, 2019) |
"The gastroprotective property of (-)-myrtenol, a monoterpenoid, has been demonstrated previously against acute gastric ulceration induced by ethanol." | 3.91 | (-)-Myrtenol accelerates healing of acetic acid-induced gastric ulcers in rats and in human gastric adenocarcinoma cells. ( Braga, AD; Lopes, MTP; Nunes, PIG; Oliveira, FTB; Oliveira, RCM; Rao, VS; Santos, FA; Santos, VG; Silva, ACA; Sousa, DP; Viana, AFSC; Viana, DA, 2019) |
"o) on chronic gastric ulcer induced by acetic acid in rats, a model that resembles the ulcer in humans." | 3.91 | Hesperidin, a citrus flavanone glycoside, accelerates the gastric healing process of acetic acid-induced ulcer in rats. ( Boeing, T; Bolda Mariano, LN; Cechinel-Filho, V; da Silva, LM; de Andrade, SF; de Souza, P; Dos Santos, AC; Longo, B; Mariott, M; Pezzini, BC; Somensi, LB, 2019) |
"Gastric ulceration was experimentally generated by administration of single oral doses of indomethacin (30 mg/kg) to fasted rats." | 3.91 | Antiulcer activity of Cyperus alternifolius in relation to its UPLC-MS metabolite fingerprint: A mechanistic study. ( Abdallah, HMI; Efferth, T; Elshamy, AI; Farag, MA; Farrag, ARH; Gendy, AEGE; Hegazy, MF; Khattab, AR; Mohamed, TA, 2019) |
"Preclinical Research & Development The objective of the present study was to evaluate the tapentadol-diclofenac combination in three dose-ratios in the mouse acetic acid-induced visceral pain and their ulcerogenic activity on the stomachal mucous." | 3.88 | Assessment of the antinociceptive and ulcerogenic activity of the tapentadol-diclofenac combination in rodents. ( Alonso-Castro, ÁJ; Granados-Soto, V; Isiordia-Espinoza, MA; Sánchez-Enriquez, S; Zapata-Morales, JR, 2018) |
"In this rat study involving males, intact (cycling) females, and ovariectomized females, gastric ulcers were induced using acetic acid." | 3.88 | Sex-specific effects of ( Bueno, G; Camargo, ACL; da Rocha, LRM; da Silva, LM; de Andrade, SF; Dos Santos, C; Dos Santos, RC; Hiruma-Lima, CA; Justulin Júnior, LA; Nunes, VVA; Ohara, R; Périco, LL; Rodrigues, VP; Steimbach, VMB; Vilegas, W, 2018) |
"This study was conducted to investigate the effects of nitric oxide (NO) in acetic acid-induced gastric ulcer of rats and the underlying mechanisms." | 3.85 | Nitric oxide donor protects against acetic acid-induced gastric ulcer in rats via S-nitrosylation of TRPV1 on vagus nerve. ( Gong, L; Han, T; Li, J; Liu, C; Tang, Y; Xue, B; Yu, X, 2017) |
"Background This study aimed to evaluate the effects of the position of an acetic acid-induced gastric ulcer and the effects of prokinetic drugs on gastric emptying." | 3.85 | Gastric emptying after artificial ulceration in rats: differences due to the site of the ulcer and the effects of prokinetic drugs. ( Kobayashi, O; Shimizu, K; Uchida, M, 2017) |
"Carbon monoxide (CO), a gaseous mediator produced by haem oxygenases (HOs), has been shown to prevent stress-, ethanol-, aspirin- and alendronate-induced gastric damage; however, its role in gastric ulcer healing has not been fully elucidated." | 3.85 | Carbon monoxide released from its pharmacological donor, tricarbonyldichlororuthenium (II) dimer, accelerates the healing of pre-existing gastric ulcers. ( Brzozowski, T; Chmura, A; Ginter, G; Hubalewska-Mazgaj, M; Kwiecien, S; Magierowska, K; Magierowski, M; Pajdo, R; Sliwowski, Z, 2017) |
"The purpose of our investigative work has been to determine whether there can be therapeutic roles in the administration of sildenafil citrate, heparin and several neuropeptides on an animal model where gastric ulcers were induced with acetic acid, and to compare their efficacy." | 3.85 | Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017) |
"Overall the data indicate that low dose heparin, and especially sildenafil citrate and neuropeptides, can be used clinically as an alternative approach in the treatment of the gastric ulcer." | 3.85 | Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017) |
""Unhealed gastric ulcers" were induced using indomethacin following the establishment of acetic-acid-induced chronic gastric ulcers." | 3.85 | Healing and Antisecretory Effects of Aqueous Extract of ( Amang, AP; Emakoua, J; Enow-Orock, GE; Mbah, G; Mezui, C; Nkwengoua, EZ; Siwe, GT; Tan, PV, 2017) |
"In order to elucidate the contribution of cycloxygenase (COX) enzymes in the anti-oxidant and anti-inflammatory mechanisms of nesfatin-1, which improves the healing process of chronic gastric ulcers, either acetic acid (80%; ulcer groups; n = 40) or saline (control groups; n = 40) was applied to the serosal surface of male Sprague Dawley rats' stomachs for 1 min." | 3.85 | Anti-inflammatory effects of nesfatin-1 on acetic acid-induced gastric ulcer in rats: involvement of cyclo-oxygenase pathway. ( Cantali-Ozturk, C; Demirci, EK; Kolgazi, M; Ozdemir-Kumral, ZN; Sirvanci, S; Yegen, BC; Yuksel, M, 2017) |
"The model of gastric ulcer was imitated by acetic acid in rats." | 3.83 | [Study on Variation of Gastroprotective Effect of Atractylodes lancea Rhizome Before and After Processing]. ( Cai, Q; Jia, TZ; Yu, Y, 2016) |
"The gastroprotective effect of Atractylodes lancea rhizome was enhanced after stir-frying with wheat bran in the rat model of gastric ulcer induced by acetic acid." | 3.83 | [Study on Variation of Gastroprotective Effect of Atractylodes lancea Rhizome Before and After Processing]. ( Cai, Q; Jia, TZ; Yu, Y, 2016) |
" This study evaluated the mechanisms involved in the gastric ulcer healing of the hydroalcoholic extract from green tea (GEt), its ethyl acetate fraction, (GEAc) and epigallocatechin gallate (EGCG) using the model of acetic acid-induced gastric ulcer in rats." | 3.83 | Healing mechanisms of the hydroalcoholic extract and ethyl acetate fraction of green tea (Camellia sinensis (L.) Kuntze) on chronic gastric ulcers. ( Baggio, CH; Borato, DG; da Silva, LM; de Souza, LM; Iacomini, M; Maria-Ferreira, D; Scoparo, CT; Werner, MF, 2016) |
"This research was performed to explore the protective effect of cod skin collagen peptides (CCP) on gastric ulcer induced by acetic acid." | 3.83 | Protective Effect of Cod (Gadus macrocephalus) Skin Collagen Peptides on Acetic Acid-Induced Gastric Ulcer in Rats. ( Hou, H; Li, B; Niu, H; Wang, Z; Zhang, Z, 2016) |
" The gastroprotective and ulcer healing activities of HEPu were evaluated using acidified ethanol (acute) and acetic acid (chronic) gastric ulcer models in rodents." | 3.83 | Piper umbellatum L.: A medicinal plant with gastric-ulcer protective and ulcer healing effects in experimental rodent models. ( Balogun, SO; da Silva Junior, IF; Damazo, AS; de Oliveira, RG; Martins, DTO, 2016) |
" Models of acute gastric ulcer induction by ethanol and indomethacin and of chronic ulcer by acetic acid were used." | 3.81 | Antiulcerogenic activity of Carica papaya seed in rats. ( Argadoña, EJ; Cardoso, CA; Carollo, CA; Carrasco, V; Cordeiro, KW; Freitas, Kde C; Pinto, LA, 2015) |
"The model of gastric ulcer was imitated by acetic acid in rats, and AL was gavaged." | 3.81 | Comparison of the anti-ulcer activity between the crude and bran-processed Atractylodes lancea in the rat model of gastric ulcer induced by acetic acid. ( Cai, Q; Jia, TZ; Jiang, N; Ma, MY; Min, DY; Yu, Y; Yuan, Y, 2015) |
"In order to demonstrate the possible protective effects of estrogen receptor (ER)-α and ERβ receptor subtypes in the pathogenesis of colonic and gastric oxidant damage, experimental ulcer and colitis were induced by acetic acid, and the animals were randomly divided as colitis, ulcer, and their corresponding non-ulcer and non-colitis control groups." | 3.80 | Estrogen alleviates acetic acid-induced gastric or colonic damage via both ERα- and ERβ-mediated and direct antioxidant mechanisms in rats. ( Ercan, F; Kumral, ZN; Memi, G; Yeğen, BC, 2014) |
"The gastric ulcer model were established by acetic acid, water-immersion stress, aspirin induction, pyloric ligation in rats, in order to observe the effect of Weiyangning pills against experimental gastric ulcer and study its effect on the content of nitric oxide (NO) and epidermal growth factor (EGF), gastric mucosal blood flow, the content of PGE2, gastric secretion, gastric acid content and the activity of pepsin." | 3.79 | [Study on efficacy and mechanism of weiyangning pills against experimental gastric ulcer]. ( Cao, HY; Huang, P; Liu, J; Wen, S; Wu, QH; Xu, JJ, 2013) |
" AT and 6-HL exhibited anti ulcer activity in experimentally induced ulcer models including cold restraint stress (CRU), alcohol (AL), pylorus ligation-induced gastric ulcer (PL) models and they also showed ulcer healing effect in chronic acetic acid-induced ulcer model (AC)." | 3.79 | Arbortristoside-A and 7-O-trans-cinnamoyl-6β-hydroxyloganin isolated from Nyctanthes arbortristis possess anti-ulcerogenic and ulcer-healing properties. ( Barthwal, MK; Mishra, V; Narender, T; Palit, G; Pandeti, S; Pandey, HP; Shukla, A, 2013) |
"Gastric ulcers were induced by the serosal application of 100% acetic acid, and the areas of the ulcers were measured thereafter." | 3.79 | NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4(+)VEGFR1(+) cells to the ulcer granulation tissues. ( Ae, T; Amano, H; Eshima, K; Hosono, K; Ito, Y; Katada, C; Koizumi, W; Majima, M; Minamino, T; Ohno, T; Sato, T; Shibuya, M; Suzuki, T, 2013) |
"The effect of fumonisin B1, an inhibitor of ceramide synthase, and of d,l,-threo-1-phenyl-2-hexadecanoylamino-3-morpholino-1-propanol (PPMP) and N-butyldeoxynojirimycin (NB-DNJ), both inhibitors of glucosylceramide synthase, on the accumulation of ceramide and formation of gastric ulcer were examined in the rat model of acetic acid-induced gastric ulcer." | 3.79 | Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. ( Hibi, T; Miura, S; Mizushima, T; Nagata, H; Nakashita, M; Suzuki, H; Taki, T; Uehara, K, 2013) |
"Fumonisin B1 attenuated acetic acid-induced gastric ulcer formation, associated with a decrease in the number of apoptotic cells." | 3.79 | Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. ( Hibi, T; Miura, S; Mizushima, T; Nagata, H; Nakashita, M; Suzuki, H; Taki, T; Uehara, K, 2013) |
"We evaluate the curative efficacy of the ethanolic extract (EET) of roots from Arctium lappa (bardana) in healing of chronic gastric ulcers induced by 80% acetic acid in rats and additionally studies the possible mechanisms underlying this action." | 3.79 | Ethanolic extract of roots from Arctium lappa L. accelerates the healing of acetic acid-induced gastric ulcer in rats: Involvement of the antioxidant system. ( Allemand, A; André, E; Baggio, CH; Cipriani, TR; da Silva, LM; Dartora, N; de Souza, LM; Dos Santos, AC; Marques, MC; Mendes, DA; Werner, MF, 2013) |
" In carrageenan-induced rat paw oedema test, compound 2c and 2f exhibited good anti-inflammatory effect at 3rd h, whereas compounds 2c, 2e, 2d, 2g and 2h showed activity in croton oil induced ear oedema assay in mice." | 3.78 | Fluorine bearing sydnones with styryl ketone group: synthesis and their possible analgesic and anti-inflammatory activities. ( Deshpande, SR; Pai, KV, 2012) |
" The acetic acid-induced gastric ulcer model, Western blotting assay (COX-1, COX-2 and EGF) and immunohistochemical localization of HSP-70, PCNA and COX-2 were also used to evaluate the Rhizophora mangle healing properties." | 3.78 | Mechanisms of action underlying the gastric antiulcer activity of the Rhizophora mangle L. ( Almeida, AC; da Silva, MA; da Silva, MS; de-Faria, FM; Dunder, RJ; Luiz-Ferreira, A; Pellizzon, CH; Rozza, AL; Souza-Brito, AR; Takayama, C; Toma, W; Vilegas, W, 2012) |
"Application of acetic acid topically to the mucosal or serosal side of the stomach has been well used to create a chronic gastric ulcer model." | 3.78 | Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model. ( Cao, H; Chen, D; Johannessen, H; Kodama, Y; Okabe, S; Takahashi, R; Wang, TC; Zhao, CM, 2012) |
" Severe necrosis in the cancer was observed in the side exposing to acetic acid, but not in the control side, shortly after the treatment (i." | 3.78 | Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model. ( Cao, H; Chen, D; Johannessen, H; Kodama, Y; Okabe, S; Takahashi, R; Wang, TC; Zhao, CM, 2012) |
"Topical application of acetic acid either from mucosal or serosal surface promptly caused the necrosis of tumor, suggesting the potential approach of this simple and reliable method as a cytoreductive treatment of gastric cancer in patients through endoscopy or laparoscopy." | 3.78 | Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model. ( Cao, H; Chen, D; Johannessen, H; Kodama, Y; Okabe, S; Takahashi, R; Wang, TC; Zhao, CM, 2012) |
"The preventive and healing properties of Croton urucurana bark methanol extract (CUE) were evaluated in experimental models of acute (ethanol and indomethacin) and chronic (acetic acid) gastric ulcers." | 3.78 | Antiulcerogenic effect of Croton urucurana Baillon bark. ( Aparecida Pinto, L; de Cássia Freitas, K; Faloni de Andrade, S; Leite Kassuya, CA; Nazari Formagio, AS; Wolff Cordeiro, K, 2012) |
"To observe the effects and mechanisms of Pongamia pinnata root flavonoids (PRF) on the experimental gastric ulcer induced by acetic acid and to study the mechanism of PRF on the quality of ulcer healing." | 3.78 | [Effect of Pongamia pinnata root flavonoids on the quality of ulcer healing and expression of EGF and TGF-alpha in the rat model of gastric ulcer induced by acetic acid]. ( Huang, XZ; Liu, KY; Zhu, Y, 2012) |
"The models were established by acetic acid erosion, the quality of ulcer healing of PRF on the model of gastric ulcer were observed." | 3.78 | [Effect of Pongamia pinnata root flavonoids on the quality of ulcer healing and expression of EGF and TGF-alpha in the rat model of gastric ulcer induced by acetic acid]. ( Huang, XZ; Liu, KY; Zhu, Y, 2012) |
" The pharmacological activity of AFE and pure scopoletin at the same equivalent dose present in AFE was investigated in rat on gastro-esophageal inflammatory models (acid reflux esophagitis, acute gastritis induced by ethanol and serotonin, and chronic gastric ulcer induced by acetic acid); gastric biochemical parameters and gastrointestinal motility." | 3.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
"50 g/kg) significantly prevented the formation of acid reflux esophagitis, reduced the formation of ethanol-induced acute gastric lesions, suppressed the development of gastric lesions in response to serotonin, and accelerated the healing of acetic acid-induced chronic gastric ulcer in rats with equal potency to those obtained by standard antisecretory agents (ranitidine and lansoprazole)." | 3.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
" (Rubiaceae) fruit, commonly known as "Noni", in an aqueous extract preparation (AFE) as used in Thai traditional medicine and its biomarker scopoletin on gastro-esophageal inflammatory models that are related to the claimed pharmacological properties of AFE and/or resembled the human esophagitis or gastric ulcer." | 3.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
" The acetic acid-induced gastric ulcer model and Western Blot assay (COX-2 and EGF) were also used to evaluate the OEH healing capacity." | 3.77 | Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae). ( de Almeida, AC; de-Faria, FM; Dunder, RJ; Hiruma-Lima, CA; Luiz-Ferreira, A; Manzo, LP; Pellizzon, CH; Rehen, CS; Rozza, AL; Salvador, MJ; Socca, EA; Souza-Brito, AR; Takayama, C; Valim-Araújo, Dde A, 2011) |
" They have been tested for analgesic activity by acetic acid induced writhing in mice and for anti-inflammatory activity by carrageenan induced rat paw edema at 100 mg/kg body weight p." | 3.77 | Design and synthesis of certain mesoionic sydnonyl styrylketones as potential nonsteroidal antiinflammatory agents. ( Deshpande, SR; Pai, KV; Pai, RS, 2011) |
"Chronic gastric ulcer was induced by an injection of 100% glacial acetic acid into the submucosal layer of the glandular stomach, then the area of all ulcers was added together as the ulcer index and inhibition rate of ulcer was calculated." | 3.77 | Activity of DBXX granules on anti-gastric ulcer and decreasing the side effect of chemotherapy in S180 tumor-bearing mice. ( Cao, Y; Han, N; Lin, X; Liu, Z; Xue, R; Yin, J, 2011) |
" Six weeks following streptozotocin or saline injection, gastric ulcers were induced by serosal application of acetic acid." | 3.77 | Role of activation of 5'-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats. ( Baraka, AM; Deif, MM, 2011) |
"The potential utility of 5'-adenosine monophosphate-activated protein kinase (AMPK)-activating agents, such as metformin, in inducing angiogenesis, could be a promising approach to promote healing of gastric ulcers complicated by diabetes mellitus." | 3.77 | Role of activation of 5'-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats. ( Baraka, AM; Deif, MM, 2011) |
"Administration of metformin, but not pioglitazone, resulted in a significant decrease in the gastric ulcer area, a significant increase in epithelial regeneration assessed histologically, a significant increase in the number of microvessels in the ulcer margin, a significant increase in gastric vascular endothelial growth factor concentration and gastric von Willebrand factor as well as a significant increase in gastric phospho-AMPK." | 3.77 | Role of activation of 5'-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats. ( Baraka, AM; Deif, MM, 2011) |
" The antiulcer effect of an extract from cochinchina momordica seeds (SK-MS10) was evaluated in a rat model of acetic acid-induced gastric ulcers." | 3.76 | Enhancement of gastric ulcer healing and angiogenesis by cochinchina Momordica seed extract in rats. ( Jung, HC; Kang, JM; Kim, B; Kim, JH; Kim, JS; Kim, N; Lee, BY; Lee, HS; Lee, MK; Park, JH; Song, IS, 2010) |
" This study aimed to determine the role of viable Lactobacillus in the healing of acetic acid-induced chronic gastric ulcer." | 3.76 | Yogurt containing Lactobacillus gasseri OLL 2716 (LG21 yogurt) accelerated the healing of acetic acid-induced gastric ulcer in rats. ( Kurakazu, K; Shimizu, K; Uchida, M, 2010) |
" Here, we assessed whether rats infected with the tapeworm Hymenolepis diminuta were protected from gastric ulceration induced by the serosal application of acetic acid." | 3.75 | Acetic acid induced ulceration in rats is not affected by infection with Hymenolepis diminuta. ( McKay, DM; Wallace, JL, 2009) |
"To evaluate the role of ALA treatment on the healing of acetic acid-induced gastric ulcer, rats were given ALA (35 mg/kg/day) or saline for 3 days before the induction of ulcer and the treatment was continued twice daily for 2 days (early) or 10 days (late) until they were decapitated." | 3.75 | Alpha-lipoic acid improves acetic acid-induced gastric ulcer healing in rats. ( Ercan, F; Erzik, C; Karakoyun, B; Yeğen, BC; Yüksel, M, 2009) |
"This study is to investigate therapeutic effect of astaxanthin on acetic acid-induced gastric ulcer in rats." | 3.75 | [Therapeutic effect of astaxanthin on acetic acid-induced gastric ulcer in rats]. ( Fu, Y; Ruan, H; Yang, Q; Zhang, Z; Zhu, X, 2009) |
" Optimal effective dose of PPSM (25 mg/kg) showed antiulcerogenic activity against acute gastric ulcers (GU) induced by pylorus ligation and aspirin and duodenal ulcer induced by cysteamine but not against ethanol-induced GU." | 3.75 | Effect of methanolic extract of Pongamia pinnata Linn seed on gastro-duodenal ulceration and mucosal offensive and defensive factors in rats. ( Agarwal, PK; Dorababu, M; Goel, RK; Goel, S; Joshi, VK; Prabha, T; Singh, A, 2009) |
" Chronic gastric ulcers were induced in male Wistar rats by the application of 100% acetic acid to the serosal surface of the stomach on 60 sec." | 3.75 | [Influence of honey, royal jelly and propolis on accelerating acetate healing of experimental gastric ulcers in rats]. ( Belostotskiĭ, NI; Dubtsova, EA; Kas'ianenko, VI; Lazebnik, LB, 2009) |
"In the present study, we compared the effects of alpha-tocopherol and probucol, antioxidants, on the healing of acetic acid-induced gastric ulcers in 8-, 48- and 96-week-old rats." | 3.74 | Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol. ( Ishihara, M; Ito, M; Kojima, R, 2008) |
"A series of fenamate quinazolinyl analogues, viz acids 6a-d, esters 6e-h, carbohydrazides 7a-d, arylidenes 8a-d, oxadiazol-2-ones 13a-d and oxadiazol-2-thiones 14a-d, have been prepared and screened for their analgesic (acetic acid-induced writhing), anti-inflammatory (carrageenan-induced rat paw edema) activities as well as their ulcerogenic effects." | 3.74 | Synthesis, analgesic and anti inflammatory activities of some new fenamate analogues. ( Alafeefy, AM, 2008) |
" To determine whether sequentially applied stimuli interact, we determined visceromotor responses (VMR) to gastric distension, measured at baseline and 60 min after instillation of saline, glycocholic acid (GCA) or ethanol through a gastrostomy in controls and rats with gastric ulcers." | 3.74 | Luminal stimuli acutely sensitize visceromotor responses to distension of the rat stomach. ( Bielefeldt, K; Gebhart, GF; Lamb, K, 2007) |
"Gastric ulcers were induced in male rats by serosal application of acetic acid." | 3.74 | [Effect of mucosal protective on the quality of gastric ulcer healing]. ( Chen, K; Chen, SJ; Deng, YY; Liu, WL; Qian, Y; Si, JM; Sun, KK; Wang, LJ; Wu, JG; Zhu, YF, 2007) |
" In the present study, we examined the effect of alendronate on the healing of acetic acid-induced gastric ulcers in rats and investigated the mechanism involved in this action both in vivo and in vitro using the rat gastric epithelial cell line (RGM1)." | 3.74 | Impairment of gastric ulcer healing by alendronate, a nitrogen-containing bisphosphonate, in rats. ( Aihara, E; Amagase, K; Hayashi, S; Nishikawa, K; Takeuchi, K, 2007) |
"The effect of peroxisome proliferator-activated receptor-alpha (PPAR-alpha) on gastric secretion and gastric cytoprotection was evaluated using five different models of gastric ulcers: acetic acid-induced chronic gastric ulcers, pylorus ligation, ethanol-induced, indomethacin-induced and ischemia-reperfusion-induced gastric ulcers." | 3.74 | Effect of peroxisome proliferator-activated receptor-alpha agonist (bezafibrate) on gastric secretion and gastric cytoprotection in rats. ( Asad, M; Hrishikeshavan, HJ; Pathak, R; Prasad, S, 2007) |
"Gastric ulcers were induced with acetic acid in rats; aspirin was administrated by gavage from day 25 to day 54 after ulcer induction." | 3.74 | Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007) |
"Aspirin enhance the recurrence of gastric ulcer." | 3.74 | Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007) |
" once daily for 1 week, markedly delayed the healing of acetic acid-induced gastric ulcers with the suppression of basic fibroblast growth factor (bFGF) expression." | 3.74 | Prophylactic effect of rebamipide against the irritative and healing impairment actions of alendronate in rat stomachs. ( Aihara, E; Amagase, K; Hayashi, S; Kato, S; Takeuchi, K, 2007) |
"The healing effects on gastric ulcers inducted by subserosal injection of acetic acid were evaluated by macroscopic and microscopic measures, immunohistochemistry and cell counting in rats treated with MeOH extract of Mouriri pusa (250 mg/kg, p." | 3.74 | Studies of gastric mucosa regeneration and safety promoted by Mouriri pusa treatment in acetic acid ulcer model. ( Andreo, M; Hiruma-Lima, CA; Kushima, H; Pellizzon, CH; Takahira, RK; Vasconcelos, PC; Vilegas, W, 2008) |
" Gastric ulcers were induced by serosal application of absolute acetic acid." | 3.74 | Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis. ( Ae, T; Amagase, K; Arai, K; Hattori, Y; Hayashi, I; Hosono, K; Komine, R; Kurihara, H; Kurihara, Y; Majima, M; Mizuguchi, S; Oh-Hashi, Y; Ohno, T; Okabe, S; Saeki, T; Saigenji, K; Suzuki, T, 2008) |
" Acetic acid-induced gastric ulcers were produced in mice after BM transplantation." | 3.74 | Cultured bone marrow cell local implantation accelerates healing of ulcers in mice. ( Egawa, S; Hayashi, N; Iijima, H; Irie, T; Ishii, S; Kakiuchi, Y; Kawano, S; Nishida, T; Shinzaki, S; Tsuji, S; Tsujii, M; Tsutsui, S; Yasumaru, M; Yoshio, T, 2008) |
" In a chronic model, by acetic acid-induced gastric ulcers, COX-2 was expressed at 7 days and was also associated with PGE(2) increase." | 3.73 | COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions. ( Alarcón de la Lastra, C; Bruseghini, L; Manuel Herrerias, J; Motilva, V; Sánchez-Fidalgo, S, 2005) |
"All inflammation parameters were increased by acetic acid-induced colitis or ethanol-induced gastric ulcer compared with the control group." | 3.73 | Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes. ( Cevík, H; Ercan, F; Erkanli, G; Işman, CA; Yeğen, BC, 2005) |
"The objective of the present study has been to advance knowledge of the gastric role played by the amino acid L-Arginine (L-Arg) in the evolution of a chronic gastric ulcer." | 3.73 | Administration of L-arginine reduces the delay of the healing process caused by ibuprofen. Implication of COX and growth factors expression. ( Bruseghini, L; Esteras, A; Illanes, M; Martín-Lacave, I; Motilva, V; Sánchez-Fidalgo, S, 2005) |
" Since compounds with cytoprotective and antioxidant effects can improve healing of gastroduodenal ulcer induced by noxious agents, this work investigated the healing effect of D- 002 on acute and chronic gastric ulcers induced with indomethacin and acetic acid, respectively, in rats." | 3.73 | Therapeutic effect of D-002 (abexol) on gastric ulcer induced experimentally in rats. ( Arruzazabala, L; Carbajal, D; Más, R; Molina, V, 2005) |
" Gaultherin, 2-[(6-O-beta-D-Xylopyranosyl-beta-D-glucopyranosyl)oxy] benzoic acid methyl ester, a natural salicylate derivative extracted from Gaultheria yunnanensis, has been shown to have analgesic and anti-inflammatory effects and lack gastric ulcerogenic effect compared to aspirin in our primary study." | 3.73 | Gaultherin, a natural salicylate derivative from Gaultheria yunnanensis: towards a better non-steroidal anti-inflammatory drug. ( Ding, Y; Du, GH; He, XL; Zhang, B, 2006) |
"To assess the synergistic action of famotidine (FMD) and chlorpheniramine (CPA) on acetic acid-induced chronic gastric ulcer in rats." | 3.73 | Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats. ( Chen, C; Qin, Z, 2005) |
"The synergistic action of FMD and CPA on acetic acid-induced chronic gastric ulcer in rats decreases the incidence of ulcer and also enhances the healing of ulcer." | 3.73 | Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats. ( Chen, C; Qin, Z, 2005) |
"The effect of MXY to the mice's gastric ulcer induced by hydrochloric acid-ethanol, reserpine, and chronic gastric ulcer induced by acetic acid were observed." | 3.73 | [Study of the effect of exceed critical extracts from Radix Aucklandiae on experimental gastric ulcer model]. ( Han, J; Lin, H; Rong, X; Zhong, Z, 2005) |
" The aim of this study was to investigate the effects of selective or non-selective inhibition of NOS on the expression and activity of COX-2 during healing of acetic acid-induced gastric ulcers in rats." | 3.73 | Differential effects of selective and non-selective inhibition of nitric oxide synthase on the expression and activity of cyclooxygenase-2 during gastric ulcer healing. ( Cho, CH; Guo, JS; Koo, MW; Wang, JY, 2006) |
" Dose dependent percent inhibition of granuloma formation, exudate volume, total leukocyte count was observed in 4e (25, 50 and 100 mg/kg) and celecoxib (CAS 169590-42-5; 5 mg/kg) treated groups in the cotton pellet granuloma and granuloma pouch technique, respectively, in rats." | 3.73 | Evaluation of anti-inflammatory and analgesic activity of a new class of biphenyl analogs in animal models of inflammation. ( Bodhankar, SL; Kulkarni, VM; Rathi, BS; Wagh, NK, 2006) |
" When the effect of test compound was evaluated on the 15th day after acetic acid injection to rats, repeated oral administration of tea catechin (25, 50, 100 mg/kg twice daily) dose-dependently accelerated the healing of acetic acid-induced chronic gastric ulcers." | 3.73 | Anti-ulcer effect of tea catechin in rats. ( Hamaishi, K; Ito, M; Kojima, R, 2006) |
"Gastric ulcer was induced in rat by acetic acid according Okeba's method with some modification and the recurrence model was induced by IL-1beta." | 3.73 | [Effects of jianwei yuyang granule on inflammatory reaction and NF-kappaB expression in rat gastric mucosa of ulcer healing and recurrence]. ( Cao, Y; Chen, YQ; Li, JB; Ling, JH; Pan, YZ; Shen, DZ, 2006) |
" Since prostaglandins are inducers of hepatocyte growth factor (HGF), we examined the effect of rebamipide on the expression of HGF, c-met, cyclooxygenase-2 (Cox-2) and subtype of the prostaglandin E2 receptor (EP2) in acetic acid-induced gastric ulcer, a model of human ulcer." | 3.72 | Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor. ( Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A, 2003) |
" Gastric ulcers were produced by injecting 50 microl of 20% acetic acid into subserosa of the border between the fundic and antral gland areas." | 3.72 | Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor. ( Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A, 2003) |
"To identify the pathogenesis of gastric ulcers by comparing injury to the nonglandular gastric mucosa of horses caused by hydrochloric acid (HCl) or volatile fatty acids (VFAs)." | 3.72 | Effects of hydrochloric, acetic, butyric, and propionic acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses. ( Andrews, FM; Argenzio, RA; Mathew, AG; Nadeau, JA; Patton, CS; Saxton, AM, 2003) |
"Previous work demonstrates that oleanolic acid (OA), a triterpene widely distributed in plants, shows gastroprotective effect in the ethanol, aspirin and pilorous ligature-induced gastric ulcer in rats as well as in the ethanol/hydrochloric acid-induced ulcer in mice." | 3.72 | Oleanolic acid promotes healing of acetic acid-induced chronic gastric lesions in rats. ( Astudillo, L; Rodríguez, JA; Schmeda-Hirschmann, G, 2003) |
"We previously discovered that a 4-wk course of indomethacin delivered to rats with acetic acid ulcers resulted in production of "unhealed gastric ulcers" that persisted for up to 12 wks after treatment cessation." | 3.72 | Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats. ( Amagase, K; Okabe, S; Tsukimi, Y; Yokota, M, 2003) |
" We investigated the changes in the level of gastric colonization 140 days after inducing gastric ulcer by acetic acid in the antral mucosa of a miniature pig infected with H." | 3.72 | Temporal increase in the gastric colonization of Helicobacter pylori after healing of acetic acid-induced gastric ulcer in a miniature pig. ( Iwata, M; Katsuta, M; Kikuchi, I; Koga, T; Okazaki, Y; Sato, K; Shimada, Y; Takahashi, K, 2003) |
"Effects of glucocorticoid deficiency followed by corticosterone replacement on the healing of gastric erosions and chronic gastric ulcers have been investigated in rats." | 3.72 | [Deficiency of glucocorticoid production delays the healing of acute gastric mucosal erosion and chronic ulcers in rats]. ( Bagaeva, TR; Filaretova, LP; Morozova, OIu; Podvigina, TT, 2003) |
"In this study, the healing effects of Centella asiatica water extract (CE) and asiaticoside (AC), an active constituent of CE, on acetic acid induced gastric ulcers (kissing ulcers) in rats were examined." | 3.72 | The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats. ( Cheng, CL; Guo, JS; Koo, MW; Luk, J, 2004) |
"Male Sprague Dawley (SD) rats were used in the following two studies: (i) the effects of risedronate and alendronate on gastric potential difference (PD), gastric mucosal blood flow (GMBF) and acid back-diffusion in the stomach mounted on ex vivo chamber under urethane anesthesia and; (ii) the influence of daily treatment with these drugs on the healing of acetic acid-induced gastric ulcers was examined." | 3.72 | Mucosal irritative and healing impairment action of risedronate in rat stomachs: comparison with alendronate. ( Aihara, E; Kanatsu, K; Kato, S; Okayama, M; Takeuchi, K, 2004) |
" Conversely, the healing of acetic acid-induced gastric ulcers was significantly delayed by daily administration of these drugs, yet this effect was less pronounced in the case of risedronate." | 3.72 | Mucosal irritative and healing impairment action of risedronate in rat stomachs: comparison with alendronate. ( Aihara, E; Kanatsu, K; Kato, S; Okayama, M; Takeuchi, K, 2004) |
"We used alendronate and risedronate as bisphosphonates and examined whether or not these agents have a mucosal irritative action in the stomach and impair the healing of pre-existing gastric ulcers in rats." | 3.72 | Mucosal irritative and healing impairment action of risedronate in rat stomachs: comparison with alendronate. ( Aihara, E; Kanatsu, K; Kato, S; Okayama, M; Takeuchi, K, 2004) |
"Gastric ulcers were induced in normal/NIDDM rats by various physical (2 hr cold restraint stress and 4 hr pylorus ligation) and chemical agents (ethanol, 1 ml/200 g, oral, 1 hr before; aspirin, 200 mg/kg, oral, 4 hr) and duodenal ulcers were induced by cysteamine (40 mg/200 g)." | 3.72 | Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats. ( Agrawal, VK; Aryya, NC; Dorababu, M; Goel, RK; Prabha, T; Priyambada, S, 2004) |
" Concerning the gastric effects, lavender oil, linalool and linalyl acetate oral administration protected against acute ethanol-induced gastric ulcers but did not prevent indomethacin-induced lesions indicating no interference with arachidonic acid metabolic cascade." | 3.72 | Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil. ( Ballabeni, V; Barocelli, E; Bianchi, A; Bruni, R; Calcina, F; Chiavarini, M; Impicciatore, M, 2004) |
" lucidum on the healing of gastric ulcers induced by acetic acid in the rat and to elucidate the underlying mechanisms involved." | 3.72 | Ganoderma lucidum polysaccharide fractions accelerate healing of acetic acid-induced ulcers in rats. ( Chan, E; Gao, H; Gao, Y; Lan, J; Tang, W; Zhou, S, 2004) |
"The purpose of this study was to evaluate the healing effect of interleukin-11 (IL-11) on acetic acid-induced gastric ulcer in rats." | 3.71 | Mechanism of the antiulcerogenic effect of IL-11 on acetic acid-induced gastric ulcer in rats. ( Fukuda, E; Ito, M; Matsuu, M; Nakashima, M; Nakayama, T; Sekine, I; Shichijo, K; Wen, CY, 2002) |
"Acetic acid was perfused into the gastric cavitties of 130 rats to produce animal model of /gastric ulcer." | 3.71 | [Expression and activity of cyclooxygenases-1 and -2 in acetic acid induced gastric ulcer in rats]. ( Guo, J; Koo, MW; Wang, J, 2001) |
"Acetic acid-induced gastric ulcers were prepared in 8-week-old male Wistar rats." | 3.71 | Expression of a specific mucin type recognized by monoclonal antibodies in the rat gastric mucosa regenerating from acetic acid-induced ulcer. ( Hayashida, H; Hotta, K; Ichikawa, T; Ishihara, K; Kurihara, M; Okayasu, I; Saigenji, K, 2001) |
"Proteoglycan expression was studied by immunohistochemistry and in situ hybridization in acetic acid-induced gastric ulcers in rat during early phases and during chronic ulceration." | 3.71 | Expression of decorin and biglycan in rat gastric tissue: effects of ulceration and basic fibroblast growth factor. ( Altenburger, M; Domschke, W; Konturek, JW; Kresse, H; Pohle, T; Shahin, M, 2001) |
" The acute gastric ulcer models used were pylorus ligation, indomethacin-induced and ethanol-induced gastric ulcers." | 3.71 | Effect of centrally administered prolactin on gastric and duodenal ulcers in rats. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001) |
"Expression of MIF was examined in a rat gastric ulcer model induced by acetic acid, and the functional role of MIF in acute gastric ulcer was investigated by administration of a neutralizing anti-MIF antibody." | 3.71 | Macrophage migration inhibitory factor is an important mediator in the pathogenesis of gastric inflammation in rats. ( Bucala, R; Chen, YX; Cho, CH; Chun Hui, CW; Chun, B; Fung, PC; Huang, XR; Hui, WM; Lam, SK; Lan, HY; Metz, C; Wong, BC; Wong, Y, 2001) |
"To investigate the effect of Jianpiyiqi prescription on the expression of heat shock proteins (HSPs) and the changes of HSPs in gastric-ulcerated rats, the rat model of chronic gastric ulcer was induced by acetic acid." | 3.71 | Effect of jianpiyiqi prescription on the expression of heat shock proteins in acetic acid-induced chronic gastric ulcer rats. ( Li, G; Luo, S; Tao, X, 2001) |
" The acute gastric ulcer models used were pylorus ligation, indomethacin, ethanol and histamine induced acute gastric ulcers." | 3.71 | Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001) |
"9), when given in the dose of 10-50 mg/kg, twice daily for 5 days, showed dose-dependent anti-ulcerogenic on various gastric ulcer models induced by ethanol, aspirin, 2 h cold restraint stress and 4 h pylorus ligation." | 3.71 | Prophylactic and curative effects of Bacopa monniera in gastric ulcer models. ( Babu, MD; Goel, RK; Rao, CV; Sairam, K, 2001) |
"ethanol-induced gastric lesion, aspirin-induced gastric ulcer, acetic acid-induced ulcer and Shay ulcer." | 3.71 | Effect of butanol fraction of Panax ginseng head on gastric lesion and ulcer. ( Jeong, CS, 2002) |
"To investigate the possible role of cyclooxygenase-2 (COX-2) inhibitor NS-398 in formation and healing of acetic acid-induced gastric ulcer in rats." | 3.71 | [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001) |
"Fourty eight male Sprague-Dawley rats weighed 160-180 g were perfused with acetic acid into the stomach to induce gastric ulcer and then divided into two groups." | 3.71 | [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001) |
"NS-398 inhibits COX-2 activity, thus alleviating inflammatory reaction in acetic acid induced gastric ulcer and averting further damage of tissues." | 3.71 | [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001) |
" In the second set of experiments, acetic acid-induced gastric ulcers were examined." | 3.71 | Transient increase of rat gastric amylin in the neonatal period and in experimental ulcers. ( Karlsson, FA; Li, Z; Shi, A, 2002) |
" pylori infection, indomethacin, and their combination affects the healing of gastric ulcers and whether or not such factors provoke a relapse of healed gastric ulcers in Mongolian gerbils." | 3.71 | Influence of Helicobacter pylori infection on healing and relapse of acetic acid ulcers in Mongolian gerbils. ( Ebata, M; Keto, Y; Okabe, S; Tomita, K, 2002) |
" A mechanistic study of the potentiating effects of cigarette smoking on acetic acid-induced gastric ulceration in rats was hence performed." | 3.70 | Mechanistic study of adverse actions of cigarette smoke exposure on acetic acid-induced gastric ulceration in rats. ( Cho, CH; Chow, JY; Ma, L, 1998) |
"Based on our previous studies that aspirin (ASA) -induced gastric ulceration in rats can be significantly reduced if the drug is chemically associated with phosphatidylcholine (PC), we undertook the present study to compare gastric ulcer healing rates in rats administered either unmodified or PC-complexed ASA." | 3.70 | Phosphatidylcholine-associated aspirin accelerates healing of gastric ulcers in rats. ( Kurinets, A; Lichtenberger, LM, 1998) |
"Effect of lafutidine ((+/-)-2-(furfurylsulfinyl)-N-[4-[4-(piperidinomethyl)-2-pyr idyl] oxy-(Z)-2-butenyl] acetamide, FRG-8813), a novel antiulcer agent, on the healing and relapse in acetic acid-induced gastric ulcer in rats was investigated." | 3.70 | [Effect of lafutidine, a novel antiulcer agent, on healing and relapse of acetic acid-induced gastric ulcer in rats]. ( Aoyama, M; Arai, Y; Ohnishi, H; Onodera, S; Shibata, M; Tanaka, M; Yamaura, T, 1998) |
" In this study, we examined whether this antichemotactic factor as well as chemotactic factors are involved in the indomethacin-induced delayed healing of experimental gastric ulcers." | 3.70 | Mechanism by which indomethacin delays the healing of acetic acid-induced ulcers in rats. Role of neutrophil antichemotactic and chemotactic activities. ( Fujita, H; Okabe, S; Takahashi, S, 1998) |
" Gastric ulcers were induced by serosal application of acetic acid." | 3.70 | Bacteria rapidly colonize and modulate healing of gastric ulcers in rats. ( Buret, A; Elliott, SN; McKnight, W; Miller, MJ; Wallace, JL, 1998) |
"We investigated the effect of probucol, a lipid-lowering agent with antioxidant properties, on HCl plus ethanol-induced gastric mucosal injury and on the healing of acetic acid-induced gastric ulcers in rats." | 3.70 | Anti-ulcer effects of antioxidants: effect of probucol. ( Ishihara, M; Ito, M; Suzuki, Y, 1998) |
" at an effective anti-inflammatory dose to rats with pre-existing acetic acid-induced gastric ulcer, NS-398 caused a statistically significant delay of ulcer healing." | 3.70 | Effects of novel anti-inflammatory compounds on healing of acetic acid-induced gastric ulcer in rats. ( Dyer, RD; Gilbertsen, RB; Guglietta, A; Kraus, ER; Lesch, CA; Sanchez, B; Schrier, D; Song, Y, 1998) |
"To investigate whether or not heparin can accelerate the healing process of acetic acid-induced gastric ulcers in rats and to identify the mechanisms for heparin to produce this effect, so that we can develop a new therapeutic application to heparin besides its traditional anticoagulant activity." | 3.70 | Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998) |
"Male Sprague-Dawley rats were used to produce acetic acid-induced gastric ulcers." | 3.70 | Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998) |
"Heparin with the doses used in the present study accelerated the healing of acetic acid-induced gastric ulcers in rats in a dose- and time-dependent manner, and this action was related to its effects to increase the levels of gastric mucosal PGE2 and GMBF as well as to decrease the gastric mucosal MPO activity." | 3.70 | Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998) |
"The healing of experimental gastric ulcers induced in rats is consistently delayed upon chronic treatment with indomethacin." | 3.70 | A new ulcer model, "unhealed gastric ulcers", induced by chronic treatment with indomethacin in rats with acetic acid ulcers. ( Amagase, K; Okabe, S, 1999) |
"We investigated the role of endogenous interleukin (IL)-1 in the mRNA expression of cyclooxygenase (COX)-1, COX-2, inducible nitric oxide synthase (iNOS), cytokine-induced neutrophil chemoattractant (CINC)-1, epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), hepatocyte growth factor (HGF), and transforming growth factor (TGF)-beta1 in acetic acid-induced gastric ulcers in rats." | 3.70 | Regulation by endogenous interleukin-1 of mRNA expression of healing-related factors in gastric ulcers in rats. ( Kobayashi, N; Okabe, S; Takahashi, S, 1999) |
" The pharmacokinetics of the drug were also evaluated after oral administration to rats with acetic acid-induced gastric ulcer (AIURs)." | 3.70 | Gastrointestinal absorption of a new reversible proton pump inhibitor, YJA-20379-8, and its pharmacokinetics after oral administration in acetic acid-induced gastric ulcer in rats. ( Chang, MS; Chung, SY; Han, KS; Kim, HJ; Kim, J; Lee, MG, 1999) |
" pylori infection in an acetic acid-induced gastric ulcer (AAU) model in Mongolian gerbils." | 3.70 | Distribution of Helicobacter pylori in a Mongolian gerbil gastric ulcer model. ( Akashi, T; Isobe, Y; Kaneda, Y; Kijima, H; Kimura, M; Miyata, H; Yagi, K, 1999) |
"Pylorus ligated, water immersion stress-induced, reserpine-induced, and acetic acid-induced gastric ulcers in rats or mice were prepared." | 3.70 | Effect of recombinant human basic fibroblast growth factor on stomach ulcers in rats and mice. ( Gao, MT; Li, WG; Rao, CM; Wang, JZ; Wu, YJ, 1999) |
"In acetic acid-induced gastric ulcers in rats, rh-bFGF 2." | 3.70 | Effect of recombinant human basic fibroblast growth factor on stomach ulcers in rats and mice. ( Gao, MT; Li, WG; Rao, CM; Wang, JZ; Wu, YJ, 1999) |
" In this study, we examined the effect of pentoxifylline on healing of acetic acid induced gastric ulcers in rats." | 3.70 | Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000) |
"Pentoxifylline accelerates healing of acetic acid induced gastric ulcer in rats." | 3.70 | Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000) |
"Rats with gastric ulcer received an intraperitoneal injection of 10 mg/kg pentoxifylline once daily for 14 days or for only the first 7 days or the last 7 days of the 14-day treatment period." | 3.70 | Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000) |
"To investigate the influence of water extracts of CagA-positive or -negative Helicobacter pylori on healing of chronic gastric ulcers and on connexin formation, proliferation and apoptosis, in acetic acid-induced chronic gastric ulcers in rats." | 3.70 | The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000) |
"Acetic acid was used to induce chronic gastric ulcers in rats, and a water extract of H." | 3.70 | The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000) |
"In untreated rats, acetic acid-induced gastric ulcers healed after 14 days and the electrophoretic band corresponding to connexin 32 appeared 4 days after ulcer induction." | 3.70 | The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000) |
" Furthermore, acetic acid ulcer, which is a model of chronic gastric ulcer, was experimentally induced in the stomachs of rats to assess the influence of 0." | 3.69 | Influence of ammonia solution on gastric mucosa and acetic acid induced ulcer in rats. ( Fujiki, N; Hata, M; Kato, T; Kohli, Y; Ueda, T; Yamazaki, Y, 1994) |
"Effects of treatment with free radical scavengers in the healing process of acetic acid-induced gastric ulcer on the ulcer aggravation induced by indomethacin were investigated." | 3.69 | Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats. ( Kondo, M; Matsuyama, K; Naito, Y; Nishimura, S; Yagi, N; Yoshikawa, T, 1995) |
"This study was done to elucidate whether rebamipide during the initial period of acetic acid-induced gastric ulcer affected healing and future ulcer relapse." | 3.69 | Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine. ( Arakawa, T; Fukuda, T; Kobayashi, K; Watanabe, T; Yamasaki, K, 1995) |
"Tobacco cigarette smoke attenuates injury-induced hyperemia, aggravates hypertonic saline-induced mucosal damage, inhibits ulcer margin hyperemia, and increases the size of the acetic acid-induced ulcer in the rat stomach." | 3.69 | Misoprostol reverses the inhibition of gastric hyperemia and aggravation of gastric damage by tobacco cigarette smoke in the rat. ( Iwata, F; Leung, FW, 1995) |
"The healing of acetic acid-induced gastric ulcer in rats and the effects of cimetidine and calcitonin were investigated with reference to the enzyme activity of both prolylhydroxylase and collagenase as related to histological findings." | 3.69 | Wound healing of acetic acid-induced gastric ulcer in rats and the effects of cimetidine and calcitonin, with special reference to prolylhydroxylase and collagenase enzyme activity. ( Arai, M; Komatsu, H; Kurose, I; Maruyama, K; Nakamura, M; Okazaki, I; Tsuchiya, M, 1995) |
"We determined the kinetics and phenotypes of infiltrating B cells in gastric ulcer in the rat induced by gastric injection of acetic acid (day 0)." | 3.69 | Two phenotypically distinct B lymphocytes (IgMhighIgDlow and IgMlowIgDhigh) in chronic gastric ulcer in the rat. ( Arisawa, T; Asai, J; Goto, H; Hayakawa, T; Ito, M; Ohbayashi, M; Ohmiya, N; Tsukamoto, Y, 1995) |
"The effects of IGN-2098 on the healing process of acetic acid-induced gastric ulcer was investigated in comparison with the other histamine H2-receptor antagonists, famotidine and roxatidine acetate HCl, in rats." | 3.69 | [Therapeutic effect of IGN-2098, a new antiulcer drug (H2-antagonist), in the ulcer diminishing period against acetic acid-induced gastric ulcer in rats]. ( Ikarashi, Y; Misaki, N; Ohba, S; Ohbayashi, S; Uchida, M, 1995) |
"We examined the effect of a liquid diet or a combined diet of liquid plus cellulose on the healing of gastric ulcers induced in rats in comparison with that of solid chow." | 3.69 | Acceleration of healing of gastric ulcers induced in rats by liquid diet: importance of tissue contraction. ( Okabe, S; Tsukimi, Y, 1994) |
" Eto inhibited carrageenin-induced edema in rats, adjuvant-induced arthritis in rats, acetic acid-induced writhing in mice and brewer's yeast-induced hyperalgesia and fever in rats." | 3.69 | Anti-inflammatory effects of etodolac: comparison with other non-steroidal anti-inflammatory drugs. ( Fujisawa, H; Inoue, K; Inoue, Y; Kimura, K; Kyoi, T; Motonaga, A; Ueda, F, 1994) |
"We tested the hypothesis that attenuation of the hyperemia at the margin of acetic acid-induced gastric ulcer in rats by tobacco cigarette smoke will increase the size of the ulcer in the acute and the healing stages." | 3.69 | Tobacco cigarette smoke aggravates gastric ulcer in rats by attenuation of ulcer margin hyperemia. ( Iwata, F; Leung, FW, 1995) |
"The effects of cimetidine, omeprazole and atropine sulfate on the healing of acetic acid-induced gastric ulcers in rats with limited food intake time (9:00-10:00 a." | 3.69 | Effect of cimetidine and omeprazole on gastric ulcer healing of rats with limited food intake time. ( Ito, M; Kojima, R; Segami, T; Suzuki, Y; Tsukahara, T, 1994) |
" Gastric ulcers were induced by application of acetic acid using a standard technique." | 3.69 | Effects of misoprostol on delayed ulcer healing induced by aspirin. ( Andrews, FJ; O'Brien, PE; Penney, AG, 1994) |
"Gastric ulcers were induced in rats by acetic acid treatment, and the mast cell kinetics in the lesions were studied." | 3.69 | Increase in mucosal and connective tissue-type mast cells in the stomach with acetic acid-induced ulcer in rat. ( Arizono, N; Bamba, T; Hattori, T; Nakajima, S, 1996) |
" Gastric ulcers were induced in young, adult, and aged rats using serosal or mucosal (kissing ulcers) application of acetic acid." | 3.69 | Influence of age on natural and delayed healing of experimentally-induced gastric ulcers in rats. ( Andrews, FJ; O'Brien, PE; Penney, AG, 1996) |
"We investigated the effects of cimetidine, omeprazole and atropine, antisecretory anti-ulcer agents, on the healing of gastric and duodenal ulcers simultaneously induced in the same rats." | 3.69 | Simultaneous evaluation of gastric and duodenal ulcers-healing activities of anti-ulcer agents in rats. ( Ito, M; Segami, T; Suzuki, Y, 1996) |
"To investigate the effect of capsaicin, cimetidine, and in combination, given intragastrically in the healing of acetic acid induced chronic gastric ulcer in the rat." | 3.69 | Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996) |
"Capsaicin promotes the healing of acetic acid induced gastric ulcer, probably by its gastric hyperaemic effect." | 3.69 | Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996) |
"Capsaicin protects the gastric mucosa against experimental injury while capsaicin desensitisation reduces the rate of gastric ulcer healing." | 3.69 | Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996) |
"To clarify the relationship between Helicobacter pylori and the healing of gastric ulcers, we investigated the healing of acetic acid-induced gastric ulcers in the antral mucosa of Japanese monkeys (n = 5) infected with H." | 3.69 | Helicobacter pylori infection delays the healing of acetic acid-induced gastric ulcer in Japanese monkeys. ( Fujioka, T; Kodama, R; Kubota, T; Nasu, M; Shuto, R, 1996) |
"We found indomethacin aggravates healed gastric ulcers (ulcer relapse) in rats." | 3.69 | Prevention of gastric ulcer relapse induced by indomethacin in rats by a mutein of basic fibroblast growth factor. ( Asano, S; Inada, I; Maeda, R; Murakami, I; Sato, F; Satoh, H; Shino, A, 1997) |
" Therefore, the aim of this study was to examine the role of collagenase and gelatinases A and B in the development and healing of acetic acid-induced gastric ulcer in rats." | 3.69 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
"Gastric ulcer was induced by injecting 20 microliters glacial acetic acid into gastric wall of rat stomachs." | 3.69 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
"The aim of this study was to examine the synthesis of sulfated glycosaminoglycans during normal healing of experimental acetic acid-induced gastric ulcer in rats and to investigate the effect of indomethacin, a drug known to delay ulcer healing, on this synthesis using an in vivo labelling system." | 3.69 | Changes in sulfated macromolecules produced in vivo during normal and indomethacin-delayed ulcer healing in rats. ( Andrews, FJ; Comper, WD; Lyons, KC; O'Brien, PE, 1997) |
" Northern blot analysis revealed that PGC gene expression was enhanced not only in acetic acid-induced chronic gastric ulcers but also in indomethacin-induced gastric mucosal lesions." | 3.69 | Pepsinogen C gene product is a possible growth factor during gastric mucosal healing. ( Chiba, T; Kawanami, C; Kinoshita, Y; Kishi, K; Maekawa, T; Matsushima, Y; Okada, A; Watanabe, N, 1997) |
"Procollagens alpha 1 (I), alpha 1 (III), and alpha 1 (IV) RNA and their polypeptides were assessed in acetic acid induced rat gastric ulcers by in situ hybridisation and immunohistochemistry." | 3.69 | Gastric ulcer healing in the rat: kinetics and localisation of de novo procollagen synthesis. ( Domschke, W; Gillessen, A; Herbst, H; Pohle, T; Schuppan, D; Shahin, M; Weber, C, 1997) |
"Immunohistological staining was done using the antibodies for the proliferating cell nuclear antigen prolyl 4-hydroxylase and alpha-smooth muscle actin in acetic acid induced gastric ulcers in rats." | 3.69 | Kinetics of fibroblasts in ulcer healing in rats: interference with indomethacin. ( Arisawa, T; Asai, J; Goto, H; Hase, S; Hayakawa, T; Hirose, Y; Niwa, Y; Tsukamoto, Y, 1997) |
"This study examined the relationship between healing of acetic acid-induced chronic gastric ulcer and connexin formation." | 3.69 | Relationship between healing of acetic acid-induced chronic gastric ulcer and connexin. ( Fujita, T; Kushima, R; Mine, T, 1997) |
"We investigated the influence of inhibition of nitric oxide (NO) synthase, using NG-nitro-L-arginine (L-NNA) or NG-mono-methyl-L-arginine (L-NMMA), and the effects of exogenous donor of NO, such as glyceryl trinitrate (GTN), on the healing of chronic gastric ulcers induced by acetic acid, on gastric blood flow around the ulcer and on the number of capillaries in the granulation tissue at the ulcer bed." | 3.68 | Inhibition of nitric oxide synthase delays healing of chronic gastric ulcers. ( Brzozowski, T; Konturek, SJ; Majka, J; Pytko-Polonczyk, J; Stachura, J, 1993) |
" We investigated proliferative activity in the healing process of acetic acid-induced gastric ulcer by immunohistochemical staining of PCNA and 5-bromo-2-deoxyuridine (BrdU), and the two methods were compared." | 3.68 | Cell proliferation kinetics in acetic acid-induced gastric ulcer evaluated by immunohistochemical staining of proliferating cell nuclear antigen. ( Hiramatsu, A; Inoue, K; Kitajima, T; Mizuno, T; Nakano, T; Okuhira, M; Tani, K, 1993) |
" The antiulcer activity of vinpocetine was demonstrated also in gastric injury induced by phenylbulazone and in chronic gastric ulcer induced by acetic acid." | 3.68 | Protective action of vinpocetine against experimentally induced gastric damage in rats. ( Babulová, A; Machová, J; Nosálová, V, 1993) |
"Effects of troxipide (Ku-54) on various experimental gastric ulcers in rats were studied." | 3.68 | [The pharmacodynamics of troxipide on experimental gastric ulcers in rats]. ( Fan, A; Fang, Z; Wang, J; Wang, Y; Zhang, L, 1993) |
"To clarify the ability of endoscopic ultrasonography (EUS) to diagnose gastric ulcer, we induced gastric ulcer (19 open ulcers and 11 ulcer scars) by injecting acetic acid into the stomach via an endoscope in 15 dogs." | 3.68 | Evaluation of acetic acid-induced gastric ulcers in dogs by endoscopic ultrasonography. ( Chijiiwa, Y; Fujishima, H; Maruoka, A; Misawa, T; Nawata, H, 1993) |
"We examined the effect of NC-1300-O-3 on the healing of acetic acid-induced gastric ulcers in male Donryu rats." | 3.68 | Effect of NC-1300-O-3 on healing of acetic acid-induced gastric ulcers in rats. ( Inoue, K; Okabe, S; Takagi, K, 1993) |
" Administration of bFGF (3-300 micrograms/kg/day) by an intragastric or an intraperitoneal route or sucralfate (400 mg/kg/day) orally to rats with acetic acid induced gastric ulcers, enhanced the healing rate of these ulcers during seven day treatment in a dose dependent manner." | 3.68 | Fibroblast growth factor in gastroprotection and ulcer healing: interaction with sucralfate. ( Bielanski, W; Brzozowski, T; Konturek, SJ; Majka, J; Otto, W; Stachura, J; Szlachcic, A, 1993) |
"Repeated administration of indomethacin delays the healing of acetic acid-induced gastric ulcers in rats, but the underlying mechanism remains unclear." | 3.68 | Mechanism by which indomethacin delays gastric ulcer healing in the rat: inhibited contraction of the ulcer base. ( Ogihara, Y; Okabe, S, 1993) |
"Repeated administration of indomethacin or prednisolone for 2 weeks apparently delayed the healing of initial gastric ulcers induced by acetic acid injection in rats." | 3.68 | Effects of indomethacin and prednisolone on the different stages of healing of acetic acid-induced gastric ulcers in the rat. ( Ogihara, Y; Okabe, S, 1993) |
"The effect of a proton pump inhibitor, omeprazole (OPZ), in combination with mouse epidermal growth factor (EGF), on the healing of chronic gastric ulcers induced by acetic acid in submandibular glands removed rats (SMR rat) was investigated." | 3.68 | [Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats]. ( Imai, S; Itoh, M; Joh, T; Takeuchi, T; Yokoyama, Y, 1992) |
" When administered twice daily at various doses (1-100 mg/kg) for 10 days, ebrotidine reduced dose dependently the area of chronic gastric ulcers, and it was accompanied by significantly higher contents of epidermal growth factor (EGF) in the ulcer bed than in the intact mucosa." | 3.68 | Gastroprotective and ulcer-healing activities of a new H2-receptor antagonist: ebrotidine. ( Brzozowski, T; Konturek, SJ; Majka, J, 1992) |
" Two experimental gastric ulcer models were selected: chronic acetic acid-induced ulcers and cold stress-induced ulcers." | 3.68 | [The antigastroulcerative activity of beta-sitosterol-beta-D-glucoside and its aglycone in rats]. ( Jiu, M; Xiao, M; Xiao, R; Yang, Z; You, J, 1992) |
"The localization of fibronectin (FN) and laminin (LM) and cellular kinetics of epithelium in acetic acid induced gastric ulcers were examined by immunohistochemistry, comparing fundic glands ulcer with fundic-pyloric border ulcer." | 3.68 | [The immunohistochemical study on the recurrent mechanism of acetic acid induced gastric ulcer in rats--extracellular matrix and cellular kinetics]. ( Yagi, K, 1992) |
"To investigate the destructive process of connective tissues in gastric ulcer, both collagenolytic and gelatinolytic activities were examined in the homogenates of rat acetic acid-induced gastric ulcer, a typical model of chronic ulcer." | 3.68 | Effects of H2-receptor antagonists on matrix metalloproteinases in rat gastric tissues with acetic acid-induced ulcer. ( Ito, A; Kakizaki, M; Mori, Y; Murakami, S; Nagase, H; Yamada, H, 1991) |
"We investigated the effects of cimetidine and omeprazole on angiogenesis in granulation tissue and on the healing of gastric ulcers induced by acetic acid in rats." | 3.68 | Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats. ( Goto, H; Hase, S; Segawa, K; Tsuchida, T; Tsukamoto, Y, 1990) |
"To clarify the mechanism of gastric ulcer recurrence, we studied acetic acid-induced gastric ulcers." | 3.68 | Evaluation of acetic acid-induced gastric ulcers in rats by scanning acoustic microscopy. ( Goto, H; Hase, S; Mizutani, K; Niwa, Y; Ohashi, S; Tsukamoto, Y, 1991) |
"The macroscopic and microscopic effects of 12-sulfodehydroabietic acid monosodium salt (TA-2711, CAS 86408-72-2) on the healing of acetic acid-induced gastric ulcers in rats were compared with those of sucralfate and carbenoxolone." | 3.68 | Effects of the new anti-ulcer agent 12-sulfodehydroabietic acid monosodium salt on healing of acetic acid-induced gastric ulcers in rats. ( Iwasaki, H; Magaribuchi, T; Onoda, Y; Tamaki, H, 1991) |
"Repeated administration of indomethacin markedly delays spontaneous healing of experimental gastric ulcers induced in rats." | 3.68 | Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats. ( Hirose, H; Okabe, S; Takeuchi, K, 1991) |
"The present study was designed to investigate the changes in gastric mucosal PGI2 level accompanying the healing of acetic acid-induced gastric ulcers in rats." | 3.68 | Healing of acetic acid-induced gastric ulcer and gastric mucosal PGI2 level in rats. ( Irino, O; Kawano, O; Misaki, N; Saitoh, K; Uchida, M, 1990) |
"The present study was designed to assess histologic and ultrastructural features of gastric mucosa in the areas of grossly healed ulcers (acetic acid-induced gastric ulcers) in rats." | 3.68 | "Healed" experimental gastric ulcers remain histologically and ultrastructurally abnormal. ( Dabros, W; Gergely, H; Hollander, D; Krause, WJ; Stachura, J; Tarnawski, A, 1990) |
"The present study examined the time sequence and histologic and ultrastructural features of the formation and evolution of experimental, acetic acid-induced gastric ulcerations in rats." | 3.68 | Vascular and microvascular changes--key factors in the development of acetic acid-induced gastric ulcers in rats. ( Dabros, W; Eltorai, M; Gergely, H; Hollander, D; Krause, WJ; Stachura, J; Tarnawski, A, 1990) |
"Epidermal growth factor (EGF) has been shown to enhance healing of experimental gastric ulcers when given subcutaneously or orally in the drinking water." | 3.68 | Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat. ( Endoh, K; Imai, S; Itoh, M; Iwai, A; Joh, T; Kawai, T; Matsusako, K; Takeuchi, T; Yasue, N; Yokoyama, Y, 1990) |
"Omeprazole, a gastric mucosal proton pump inhibitor, significantly and dose-dependently prevented the delayed healing of acetic acid-induced gastric ulcers in response to repeatedly administered indomethacin to rats." | 3.68 | Effect of omeprazole on delayed healing of acetic acid-induced gastric ulcers in rats. ( Nagai, H; Okabe, S; Wang, JY, 1990) |
"Combined treatment with the H2 antagonist ranitidine and the cytoprotective agent pentacaine was studied in acute gastric lesions induced by phenylbutazone and stress, in chronic gastric ulcers induced by acetic acid, and in Shay's model of gastric secretion stimulated by histamine." | 3.68 | Efficacy of combined ranitidine and pentacaine treatment in experimentally induced gastric damage in rats. ( Babul'ová, A; Benes, L; Nosál'ová, V, 1990) |
"The anti-ulcer effect of sofalcone, an isoprenyl chalcone derivative, on acetic acid-induced gastric ulcers in rats was studied histologically and histochemically." | 3.67 | Effect of 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy) chalcone (sofalcone) on chronic gastric ulcers in rats. ( Arai, I; Kimura, M; Nakane, S; Saziki, R; Tarumoto, Y, 1984) |
"The effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on various experimental gastric ulcers and gastric secretion in experimental animals was compared with that of cimetidine and cetraxate." | 3.67 | Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals. ( Aratani, S; Enomoto, H; Kimura, K; Mimura, K; Nomura, A; Ueda, F, 1984) |
"The progress of acetic acid-induced gastric ulcers in rats were sequentially observed with an endoscope for 365 days, and the influences of the ulcer-induced site, age and sex on the healing, recurrence and relapse of these ulcers were investigated." | 3.67 | [Experimental studies on gastric ulcer (6). Endoscopical evaluation of healing processes of acetic acid ulcer in rats (2): Healing, recurrence and relapse of ulcer]. ( Fukawa, K; Irino, O; Kawano, O; Misaki, N; Uchida, M, 1984) |
"In an attempt to elucidate the role of granulation vessels in the healing of gastric ulcer, healing and angiogenesis in granulation tissue of acetic acid ulcers were studied in rats." | 3.67 | Effects of prednisolone and human epidermal growth factor on angiogenesis in granulation tissue of gastric ulcer induced by acetic acid. ( Hase, S; Nakazawa, S; Segawa, K; Tsukamoto, Y, 1989) |
"The present study was undertaken to elucidate the role of mucous secreting cells in the healing of acetic acid-induced gastric ulcers in rats." | 3.67 | Physiological significance of mucous neck cell-type mucins in the healing of acetic acid-induced gastric ulcers in rats. ( Hashikura, Y; Ichikawa, H; Katsuyama, T; Kobayashi, C; Sugiyama, A, 1989) |
"We examined the changes in prolylhydroxylase (PH) and interstitial collagenase (CA) activities in the healing of acetic acid-induced gastric ulcers in rats." | 3.67 | Prolylhydroxylase and collagenase activities in the healing of acetic acid-induced gastric ulcers in rats and the effects of cimetidine and elcatonin. ( Komatsu, K; Kurose, I; Maruyama, K; Oda, M; Okazaki, I; Tsuchiya, M, 1989) |
"We investigated the roles of endogenous leukotrienes (LTs) and prostaglandins (PGs) in the healing of gastric ulcers induced by acetic acid in rats." | 3.67 | Roles of endogenous leukotrienes and prostaglandins in the healing of gastric ulcers induced by acetic acid in rats. ( Arakawa, T; Fukuda, T; Kobayashi, K; Nakamura, H; Nebiki, H; Torii, Y, 1989) |
"Changes in the pH gradient and thickness of the mucus gel layer in the healing of acetic acid-induced gastric ulcers in rats were investigated." | 3.67 | Role of the mucus gel layer in the healing of acetic acid-induced gastric ulcers in rats. ( Kawano, O; Matsueda, K; Misaki, N; Muraoka, A; Uchida, M; Umeda, N, 1989) |
"We examined the effect of human epidermal growth factor (hEGF) on the healing rate of gastric ulcers induced in rats." | 3.67 | Effects of human epidermal growth factor on natural and delayed healing of acetic acid-induced gastric ulcers in rats. ( Kuwahara, Y; Okabe, S, 1989) |
"We examined the mechanism by which repeated administration of indomethacin significantly delays the natural healing of experimental gastric ulcers induced in rats." | 3.67 | Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin. ( Okabe, S; Takeuchi, K; Wang, JY; Yamasaki, S, 1989) |
"A metalloproteinase was extracted from a medium of cultured gastric tissues following acetic acid-induced ulcer or taurocholic acid-induced gastritis, and the enzyme was partially purified by Sephadex G-200 column chromatography." | 3.67 | Production of metalloproteinase in gastric tissue with acetic acid-induced ulcer or taurocholic acid-induced gastritis. ( Ishikura, Y; Mori, Y; Murakami, S; Nakanishi, J; Tsuchiya, S, 1987) |
" Arbaprostil, given orally in doses of 1-100 micrograms/kg twice daily for 2 weeks, had little or no effect on the healing of acetic acid-induced gastric ulcers." | 3.67 | Effects of 15(R)-15-methyl prostaglandin E2 (arbaprostil) on gastric secretion and various gastric lesions induced in rats. ( Jino, H; Nishida, A; Okabe, S, 1986) |
"Chronic gastric ulcers were produced by injection of 20% acetic acid (0." | 3.67 | Effects of trimoprostil on healing and recurrence of acetic acid-induced gastric ulcer in rats. ( Nakamura, K; Umeda, Y, 1986) |
" prevented formation of ulcers induced by serotonin, indomethacin, acetylsalicylic acid or stress (acute ulcer models), its effect being greater against gastric ulcers induced by serotonin." | 3.67 | Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103). ( Hoshina, K; Naruchi, T; Takeshita, T; Yamazaki, N, 1985) |
"Changes in the incorporation of 3H-glucosamine into the macromolecular glycoprotein during the healing process of acetic acid induced gastric ulcer in rats were sequentially examined in the ulcer region and the intact region at 2, 10, 40, 80 and 365 days after the operation." | 3.67 | [Changes in the biosynthetic activity of gastric glycoproteins during the healing process of acetic acid ulcer in rats]. ( Ishikura, Y; Mori, Y; Murakami, S, 1985) |
") inhibited the development of gastric ulcers induced by pylorus ligation, water-immersion stress, aspirin and reserpine and duodenal ulcers induced by cysteamine in rats." | 3.67 | Effect of elcatonin on experimental gastric and duodenal ulcers. ( Noguchi, M; Ohno, H; Takayanagi, N, 1985) |
" Oral or intraduodenal administration of AG 629 in a dose range of 25-100 mg/kg inhibited water-immersion stress ulcer, exertion ulcer, Shay ulcer, indometacin- and acetylsalicylic acid (ASA)-induced gastric ulcer, and indomethacin-induced small intestinal ulcer in rats, histamine-induced gastric ulcer in guinea pigs, and ASA-induced gastric ulcer in dogs, though it was not effective against cysteamine-induced duodenal ulcer in rats." | 3.67 | Effects of 5-acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one, a new anti-ulcer agent, on experimental acute and chronic ulcers. ( Hirata, T; Inada, I; Inatomi, N; Maki, Y; Satoh, H; Sino, A, 1985) |
" Finally, absorption, distribution, metabolism, and excretion (ADME) was used to evaluate the bioavailability of potential compounds." | 1.72 | The effect of anti-alcoholic gastric ulcer before and after vinegar-processed Yuanhu Zhitong prescription based on spectral-effect relationship. ( Dong, J; Hou, A; Jiang, H; Kuang, H; Lv, J; Wang, S; Wang, X; Yang, L; Yu, H; Zhang, J; Zhang, S; Zheng, S, 2022) |
"Gastric ulcers were induced by submucosal injections of 40% acetic acid solution into stomach submucosa and bilateral inferior vagal ganglia were collected one week afterwards." | 1.56 | Inferior vagal ganglion galaninergic response to gastric ulcers. ( Franke-Radowiecka, A; Juranek, J; Kaleczyc, J; Mogielnicka-Brzozowska, M; Pidsudko, Z; Zalecki, M, 2020) |
"The treatment with hesperidin at 3 and 10 mg/kg, once a day, by seven days, accelerated by 34 and 62%, respectively, the ulcer healing process when compared to vehicle-treated group (99." | 1.51 | Hesperidin, a citrus flavanone glycoside, accelerates the gastric healing process of acetic acid-induced ulcer in rats. ( Boeing, T; Bolda Mariano, LN; Cechinel-Filho, V; da Silva, LM; de Andrade, SF; de Souza, P; Dos Santos, AC; Longo, B; Mariott, M; Pezzini, BC; Somensi, LB, 2019) |
"Gastric ulcer is one of the main prevalent gastrointestinal multi-etiological disorders with many associated complications and adverse effects." | 1.51 | Antiulcer activity of Cyperus alternifolius in relation to its UPLC-MS metabolite fingerprint: A mechanistic study. ( Abdallah, HMI; Efferth, T; Elshamy, AI; Farag, MA; Farrag, ARH; Gendy, AEGE; Hegazy, MF; Khattab, AR; Mohamed, TA, 2019) |
" Dose-response curves were generated for tapentadol, diclofenac, and their combination in the acetic acid-induced writhing test in mice." | 1.48 | Assessment of the antinociceptive and ulcerogenic activity of the tapentadol-diclofenac combination in rodents. ( Alonso-Castro, ÁJ; Granados-Soto, V; Isiordia-Espinoza, MA; Sánchez-Enriquez, S; Zapata-Morales, JR, 2018) |
"Acetic acid ulcers were induced either in the region between the fundus and pylorus on the anterior wall of the stomach or in the glandular region on the greater curvature of the stomach to determine whether there were regional differences in the effect of the ulcers." | 1.46 | Gastric emptying after artificial ulceration in rats: differences due to the site of the ulcer and the effects of prokinetic drugs. ( Kobayashi, O; Shimizu, K; Uchida, M, 2017) |
"Ulcers were induced by serosal application of 80 % acetic acid to the stomach of rats anaesthetized with 50 mg/kg thiopentone sodium and treatment was given three times daily." | 1.46 | Effects of quinine on gastric ulcer healing in Wistar rats. ( Adeniyi, OS; Friday, ET; Makinde, OV; Olaleye, SB, 2017) |
"Gastric ulcers was induced in the animals of 12 groups with one untreated group being left as the control (Group I - control; given normal saline (NS))." | 1.46 | Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017) |
"Gastric ulcers were induced in rats by applying acetic acid to the serosa of the stomach." | 1.43 | Glyprolines exert protective and repair-promoting effects in the rat stomach: potential role of the cytokine GRO/CINC-1. ( Andreeva, LA; Bakaeva, ZV; Myasoedov, NF; Sangadzhieva, AD; Tanaka, T; Tani, S; Torshin, VI; Wallace, JL, 2016) |
"(-)-Linalool is a monoterpene constituent of many essential oils." | 1.43 | Beta-cyclodextrin enhanced gastroprotective effect of (-)-linalool, a monoterpene present in rosewood essential oil, in gastric lesion models. ( da Costa, DS; da Silva, FV; de Barros Fernandes, H; de Cássia Meneses Oliveira, R; de Lira, KL; de Sousa, AA; Lopes, MT; Oliveira, IS; Quintans-Júnior, LJ; Viana, AF, 2016) |
"Twenty-eight gastric hyperalgesia rats and 20 control rats were used." | 1.39 | Desvenlafaxine succinate ameliorates visceral hypersensitivity but delays solid gastric emptying in rats. ( Chen, JD; Dai, F; Lei, Y; Li, S; Song, G, 2013) |
"Gastric ulcers were induced by the serosal application of 100% acetic acid, and the areas of the ulcers were measured thereafter." | 1.39 | NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4(+)VEGFR1(+) cells to the ulcer granulation tissues. ( Ae, T; Amano, H; Eshima, K; Hosono, K; Ito, Y; Katada, C; Koizumi, W; Majima, M; Minamino, T; Ohno, T; Sato, T; Shibuya, M; Suzuki, T, 2013) |
"Gastric ulcers were induced by serosal application of acetic acid in mice, and gastric tissues were processed for further evaluation." | 1.39 | High-mobility group box 1 inhibits gastric ulcer healing through Toll-like receptor 4 and receptor for advanced glycation end products. ( Arakawa, T; Fujiwara, Y; Higashimori, A; Nadatani, Y; Ohkawa, F; Shiba, M; Sogawa, M; Takeda, S; Takeuchi, K; Tanigawa, T; Tominaga, K; Watanabe, K; Watanabe, T; Yamagami, H, 2013) |
"Gastric cancer was found in both the anterior and posterior walls of the corpus in all 43 mice." | 1.38 | Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model. ( Cao, H; Chen, D; Johannessen, H; Kodama, Y; Okabe, S; Takahashi, R; Wang, TC; Zhao, CM, 2012) |
"It is important in treatment of gastric ulcers to not only prevent further ulcer formation but also enhance ulcer healing." | 1.37 | Stimulation of gastric ulcer healing by heat shock protein 70. ( Asano, T; Ishihara, T; Mizushima, T; Suemasu, S; Tanaka, K, 2011) |
"Gastric ulcers were produced by focal and serosal application of acetic acid." | 1.37 | Stimulation of gastric ulcer healing by heat shock protein 70. ( Asano, T; Ishihara, T; Mizushima, T; Suemasu, S; Tanaka, K, 2011) |
"It proved that DBXX granules showed good healing effect on the chronic gastric ulcer mice and significant effect on decreasing the side effect of chemotherapy of S180 tumor-bearing mice." | 1.37 | Activity of DBXX granules on anti-gastric ulcer and decreasing the side effect of chemotherapy in S180 tumor-bearing mice. ( Cao, Y; Han, N; Lin, X; Liu, Z; Xue, R; Yin, J, 2011) |
"Chronic gastric ulcer was induced by an injection of 100% glacial acetic acid into the submucosal layer of the glandular stomach, then the area of all ulcers was added together as the ulcer index and inhibition rate of ulcer was calculated." | 1.37 | Activity of DBXX granules on anti-gastric ulcer and decreasing the side effect of chemotherapy in S180 tumor-bearing mice. ( Cao, Y; Han, N; Lin, X; Liu, Z; Xue, R; Yin, J, 2011) |
"Gastric ulcers were produced by subserosal injection of acetic acid." | 1.36 | Enhancement of gastric ulcer healing and angiogenesis by cochinchina Momordica seed extract in rats. ( Jung, HC; Kang, JM; Kim, B; Kim, JH; Kim, JS; Kim, N; Lee, BY; Lee, HS; Lee, MK; Park, JH; Song, IS, 2010) |
"Gastric ulcers were induced by the serosal application of 100% acetic acid, and the areas of the ulcers were measured thereafter." | 1.36 | Role of microsomal prostaglandin E synthase-1 in the facilitation of angiogenesis and the healing of gastric ulcers. ( Ae, T; Akira, S; Hattori, Y; Hosono, K; Koizumi, W; Majima, M; Minamino, T; Ohno, T; Sato, T; Suzuki, T; Uematsu, S, 2010) |
"Contemporary medications used in the treatment of gastric ulcers involve the use of novel mucosal protective drugs." | 1.36 | Ginger extract and polaprezinc exert gastroprotective actions by anti-oxidant and growth factor modulating effects in rats. ( Ko, JK; Leung, CC, 2010) |
" To assess the significance of this multiple probe approach, drug concentrations in each probe location were monitored after selected compounds were dosed to the ligated stomach by oral gavage." | 1.35 | The direct comparison of health and ulcerated stomach tissue: a multiple probe microdialysis sampling approach. ( Lunte, CE; Woo, KL, 2008) |
"Carnosol was identified as a possible active constituent for the gastroprotective effect of HE." | 1.35 | Gastroprotective constituents of Salvia officinalis L. ( Baggio, CH; dos Santos, AC; dos Santos, EP; Freitas, CS; Heller, M; Horst, H; Marques, MC; Mayer, B; Micke, GA; Otuki, MF; Pizzolatti, MG; Twardowschy, A, 2009) |
"Chronic gastric ulcers were induced in male Wistar rats by the application of 100% acetic acid to the serosal surface of the stomach on 60 sec." | 1.35 | [Influence of honey, royal jelly and propolis on accelerating acetate healing of experimental gastric ulcers in rats]. ( Belostotskiĭ, NI; Dubtsova, EA; Kas'ianenko, VI; Lazebnik, LB, 2009) |
" No toxic effect was observed in all parameters evaluated." | 1.35 | Studies of gastric mucosa regeneration and safety promoted by Mouriri pusa treatment in acetic acid ulcer model. ( Andreo, M; Hiruma-Lima, CA; Kushima, H; Pellizzon, CH; Takahira, RK; Vasconcelos, PC; Vilegas, W, 2008) |
"Gastric ulcers were induced by serosal application of absolute acetic acid." | 1.35 | Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis. ( Ae, T; Amagase, K; Arai, K; Hattori, Y; Hayashi, I; Hosono, K; Komine, R; Kurihara, H; Kurihara, Y; Majima, M; Mizuguchi, S; Oh-Hashi, Y; Ohno, T; Okabe, S; Saeki, T; Saigenji, K; Suzuki, T, 2008) |
"Gastric ulcers were induced, and BM-derived cells, myofibroblasts, or phosphate-buffered saline were injected around ulcers." | 1.35 | Cultured bone marrow cell local implantation accelerates healing of ulcers in mice. ( Egawa, S; Hayashi, N; Iijima, H; Irie, T; Ishii, S; Kakiuchi, Y; Kawano, S; Nishida, T; Shinzaki, S; Tsuji, S; Tsujii, M; Tsutsui, S; Yasumaru, M; Yoshio, T, 2008) |
"Gastric ulcers were induced in male rats by serosal application of acetic acid." | 1.34 | [Effect of mucosal protective on the quality of gastric ulcer healing]. ( Chen, K; Chen, SJ; Deng, YY; Liu, WL; Qian, Y; Si, JM; Sun, KK; Wang, LJ; Wu, JG; Zhu, YF, 2007) |
"Aspirin enhance the recurrence of gastric ulcer." | 1.34 | Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007) |
"Ulcer recurrence and poor healing may be critically important to the development of serious gastrointestinal complications in patients with long-term non-steroid anti-inflammatory drugs (NSAIDs)." | 1.34 | Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007) |
"Gastric ulcers were induced with acetic acid in rats; aspirin was administrated by gavage from day 25 to day 54 after ulcer induction." | 1.34 | Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007) |
"Hydrogen sulfide is an endogenous mediator that relaxes vascular smooth muscle, exhibits several antiinflammatory activities, and contributes to gastric mucosal defense." | 1.34 | Hydrogen sulfide enhances ulcer healing in rats. ( Dicay, M; Martin, GR; McKnight, W; Wallace, JL, 2007) |
"Gastric ulcers were induced in male SD rats by serosal application of acetic acid for 60 sec." | 1.34 | Effect of dopamine on the healing of acetic acid-induced gastric ulcers in rats. ( Amagase, K; Nishikawa, K; Takeuchi, K, 2007) |
"Ketorolac is a non-steroidal anti-inflammatory drug." | 1.34 | Ketorolac-dextran conjugates: synthesis, in vitro and in vivo evaluation. ( Chaturvedi, SC; Trivedi, P; Vyas, S, 2007) |
"Ketorolac contents were evaluated by UV-spectrophotometric analysis." | 1.34 | Ketorolac-dextran conjugates: synthesis, in vitro and in vivo evaluation. ( Chaturvedi, SC; Trivedi, P; Vyas, S, 2007) |
"Melatonin is a hormone involved in the transduction of photoperiodic information, and appears to modulate a variety of neural and endocrine functions." | 1.33 | Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes. ( Cevík, H; Ercan, F; Erkanli, G; Işman, CA; Yeğen, BC, 2005) |
"Acute gastric ulcer was induced with single oral doses of indomethacin (20 mg/kg)." | 1.33 | Therapeutic effect of D-002 (abexol) on gastric ulcer induced experimentally in rats. ( Arruzazabala, L; Carbajal, D; Más, R; Molina, V, 2005) |
"Mucosal inflammation is a crucial factor for the recurrence of peptic ulcer." | 1.33 | Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils. ( Osaka, T; Sakurai, K; Yamasaki, K, 2005) |
"Ulcer recurrence was examined at 60, 100, and 140 days after production of acetic acid-induced gastric ulcers in rats." | 1.33 | Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils. ( Osaka, T; Sakurai, K; Yamasaki, K, 2005) |
"Acetic acid ulcers were produced in the rat gastric corpus; non-ulcer rats served as controls." | 1.33 | Cell proliferation in the gastric epithelium of the ulcer rat. ( Helander, HF; Li, H, 2005) |
"Gastric ulcer is a source of visceral pain." | 1.33 | Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006) |
"Gastric ulcers were induced by luminal application of 60% acetic acid under surgical conditions." | 1.33 | Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006) |
"Pathohistology of ulcer healing and recurrence was observed." | 1.33 | [Effects of jianwei yuyang granule on inflammatory reaction and NF-kappaB expression in rat gastric mucosa of ulcer healing and recurrence]. ( Cao, Y; Chen, YQ; Li, JB; Ling, JH; Pan, YZ; Shen, DZ, 2006) |
"Gastric ulcer was induced in rat by acetic acid according Okeba's method with some modification and the recurrence model was induced by IL-1beta." | 1.33 | [Effects of jianwei yuyang granule on inflammatory reaction and NF-kappaB expression in rat gastric mucosa of ulcer healing and recurrence]. ( Cao, Y; Chen, YQ; Li, JB; Ling, JH; Pan, YZ; Shen, DZ, 2006) |
"Gastric ulcers were produced by injecting 50 microl of 20% acetic acid into subserosa of the border between the fundic and antral gland areas." | 1.32 | Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor. ( Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A, 2003) |
"The gastric ulcer was induced endoscopically with 1 mL of 40% acetic acid 12 days after inoculation of H." | 1.32 | Temporal increase in the gastric colonization of Helicobacter pylori after healing of acetic acid-induced gastric ulcer in a miniature pig. ( Iwata, M; Katsuta, M; Kikuchi, I; Koga, T; Okazaki, Y; Sato, K; Shimada, Y; Takahashi, K, 2003) |
"Gastric ulcers were induced in rats and mice by the application of acetic acid and cryoinjury, respectively." | 1.32 | Roles of inducible nitric oxide synthase in the development and healing of experimentally induced gastric ulcers. ( Esumi, H; Nagata, H; Ogura, T; Sakurazawa, N; Sugita, M; Tatemichi, M, 2003) |
"Gastric ulcers were induced in normal/NIDDM rats by various physical (2 hr cold restraint stress and 4 hr pylorus ligation) and chemical agents (ethanol, 1 ml/200 g, oral, 1 hr before; aspirin, 200 mg/kg, oral, 4 hr) and duodenal ulcers were induced by cysteamine (40 mg/200 g)." | 1.32 | Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats. ( Agrawal, VK; Aryya, NC; Dorababu, M; Goel, RK; Prabha, T; Priyambada, S, 2004) |
" An initial dose-response study using 12." | 1.32 | Evaluation of Pongamia pinnata root extract on gastric ulcers and mucosal offensive and defensive factors in rats. ( Agrawal, VK; Dora Babu, M; Goel, RK; Prabha, T; Priyambada, S, 2003) |
"Gastric ulcers were induced in male Wistar rats by applying acetic acid to the fundus of the stomach." | 1.31 | Mechanism of the antiulcerogenic effect of IL-11 on acetic acid-induced gastric ulcer in rats. ( Fukuda, E; Ito, M; Matsuu, M; Nakashima, M; Nakayama, T; Sekine, I; Shichijo, K; Wen, CY, 2002) |
"Acetic acid was perfused into the gastric cavitties of 130 rats to produce animal model of /gastric ulcer." | 1.31 | [Expression and activity of cyclooxygenases-1 and -2 in acetic acid induced gastric ulcer in rats]. ( Guo, J; Koo, MW; Wang, J, 2001) |
"Pentoxifylline has many anti-inflammatory properties including inhibition of production of tumor necrosis factor alpha (TNF-alpha)." | 1.31 | Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000) |
"In untreated rats, acetic acid-induced gastric ulcers healed after 14 days and the electrophoretic band corresponding to connexin 32 appeared 4 days after ulcer induction." | 1.31 | The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000) |
"Acetic acid was used to induce chronic gastric ulcers in rats, and a water extract of H." | 1.31 | The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000) |
"Chronic gastric ulcers were induced using acetic acid and duodenal ulcers by cysteamine hydrochloride." | 1.31 | Effect of centrally administered prolactin on gastric and duodenal ulcers in rats. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001) |
"The effect of hyperprolactinaemia, induced by two or four pituitary homografts under the kidney capsule, on gastric and duodenal ulcers has been studied." | 1.31 | Effect of hyperprolactinaemia as induced by pituitary homografts under kidney capsule on gastric and duodenal ulcers in rats. ( Abraham, BK; Asad, M; Balasinor, N; Koumaravelou, K; Ramaswamy, S; Shewade, DG, 2001) |
"Chronic gastric ulcers were induced using acetic acid and duodenal ulcers by mercaptamine hydrochloride." | 1.31 | Effect of hyperprolactinaemia as induced by pituitary homografts under kidney capsule on gastric and duodenal ulcers in rats. ( Abraham, BK; Asad, M; Balasinor, N; Koumaravelou, K; Ramaswamy, S; Shewade, DG, 2001) |
"Chronic gastric ulcers were induced using acetic acid and duodenal ulcers by cysteamine hydrochloride." | 1.31 | Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001) |
"Indomethacin treatment showed a tendency to delay ulcer healing." | 1.31 | Influence of Helicobacter pylori infection on healing and relapse of acetic acid ulcers in Mongolian gerbils. ( Ebata, M; Keto, Y; Okabe, S; Tomita, K, 2002) |
"Gastric ulcers were induced by serosal application of an acetic acid solution." | 1.31 | Influence of Helicobacter pylori infection on healing and relapse of acetic acid ulcers in Mongolian gerbils. ( Ebata, M; Keto, Y; Okabe, S; Tomita, K, 2002) |
" The effects of long-term administration of NS-398 on gastric ulcers were examined." | 1.30 | Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice. ( Akamatsu, T; Kasuga, M; Matsuda, K; Mizuno, H; Noguchi, H; Sakamoto, C; Uchida, T; Wada, K, 1997) |
"No recurrence was found in the rats treated with 0." | 1.30 | Role of neutrophils in a rat model of gastric ulcer recurrence caused by interleukin-1 beta. ( Arakawa, T; Fukuda, T; Higuchi, K; Kobayashi, K; Watanabe, T, 1997) |
"In acetic acid-treated rats, this activity increased to 2." | 1.30 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
"Gastric ulcer was induced by injecting 20 microliters glacial acetic acid into gastric wall of rat stomachs." | 1.30 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
"In the model of adjuvant arthritis VUFB-16066 improves most of disease symptoms including immunopathological disturbances, which indicates possible disease-modifying activity of the drug." | 1.30 | Pharmacological profile of the novel potent antirheumatic 4-(2',4'-difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic acid. ( Andĕrova, E; Jandera, A; Kuchar, M; Panajotova, V, 1997) |
"Pretreatment with allopurinol (Allo, 5 mg/kg, i." | 1.30 | Mechanistic study of adverse actions of cigarette smoke exposure on acetic acid-induced gastric ulceration in rats. ( Cho, CH; Chow, JY; Ma, L, 1998) |
"Gastric ulcers were induced in anesthetized rats by briefly exposing the mucosal surface to 0." | 1.30 | Phosphatidylcholine-associated aspirin accelerates healing of gastric ulcers in rats. ( Kurinets, A; Lichtenberger, LM, 1998) |
"Gastric ulcers were induced by serosal application of acetic acid." | 1.30 | Bacteria rapidly colonize and modulate healing of gastric ulcers in rats. ( Buret, A; Elliott, SN; McKnight, W; Miller, MJ; Wallace, JL, 1998) |
" Heparin in the doses of 100, 500, and 1000 U/kg were administered intravenously through the tail vein once daily, starting 1 day after ulcer induction for 7 days in the dose-response experiment or heparin 1000 U/kg at a time schedule of 3, 5, and 7 days in the time-response study, respectively." | 1.30 | Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998) |
"Portal hypertension was induced by staged portal vein ligation." | 1.30 | Delayed healing of acetic-acid-induced gastric ulcer in portal hypertensive rats. ( Baatar, D; Bandoh, T; Kitano, S; Ninomiya, K; Tsuboi, S; Yoshida, T, 1999) |
"Gastric ulcers were induced by application of acetic acid to the serosal surface of the stomach." | 1.30 | Delayed healing of acetic-acid-induced gastric ulcer in portal hypertensive rats. ( Baatar, D; Bandoh, T; Kitano, S; Ninomiya, K; Tsuboi, S; Yoshida, T, 1999) |
" The results suggest that modification of the oral dose of YJA-20379-8 may not be required in gastric ulcer patients if the present rat pharmacokinetic data could be extrapolated to man." | 1.30 | Gastrointestinal absorption of a new reversible proton pump inhibitor, YJA-20379-8, and its pharmacokinetics after oral administration in acetic acid-induced gastric ulcer in rats. ( Chang, MS; Chung, SY; Han, KS; Kim, HJ; Kim, J; Lee, MG, 1999) |
" accelerated the chronic ulcer healing with a bell-shaped dose-effect curve and the best dosage was 10 kU." | 1.30 | Effect of recombinant human basic fibroblast growth factor on stomach ulcers in rats and mice. ( Gao, MT; Li, WG; Rao, CM; Wang, JZ; Wu, YJ, 1999) |
"Gastric ulcers were induced by luminal application of an acetic acid solution (60%, 0." | 1.29 | Changes in gastric function and healing of chronic gastric ulcers in aged rats. ( Okabe, S; Tsukimi, Y, 1995) |
"Gastric ulcers were produced on the anterior wall of the stomach of male Sprague-Dawley rats by submucosal injection of 20% acetic acid." | 1.29 | Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats. ( Kondo, M; Matsuyama, K; Naito, Y; Nishimura, S; Yagi, N; Yoshikawa, T, 1995) |
"In the adjuvant arthritis test, the ED30 value (1." | 1.29 | Anti-inflammatory effects of etodolac: comparison with other non-steroidal anti-inflammatory drugs. ( Fujisawa, H; Inoue, K; Inoue, Y; Kimura, K; Kyoi, T; Motonaga, A; Ueda, F, 1994) |
"Gastric ulcers were produced by luminal application of 60% acetic acid (0." | 1.29 | Validity of kissing gastric ulcers induced in rats for screening of antiulcer drugs. ( Okabe, S; Tsukimi, Y, 1994) |
"Gastric ulcers were induced by application of acetic acid using a standard technique." | 1.29 | Effects of misoprostol on delayed ulcer healing induced by aspirin. ( Andrews, FJ; O'Brien, PE; Penney, AG, 1994) |
"Gastric ulcers were produced 5 days after submucosal injection of 20% acetic acid (0." | 1.29 | Effect and mechanism of sucralfate on healing of acetic acid-induced gastric ulcers in rats. ( Ogihara, Y; Okabe, S, 1993) |
"Gastric ulcers were induced in rats by acetic acid treatment, and the mast cell kinetics in the lesions were studied." | 1.29 | Increase in mucosal and connective tissue-type mast cells in the stomach with acetic acid-induced ulcer in rat. ( Arizono, N; Bamba, T; Hattori, T; Nakajima, S, 1996) |
"The influence of KU-1257 on the recurrence and relapse of acetic acid ulcers in rats was investigated grossly and histologically in comparison with that of cimetidine." | 1.29 | [Influence of KU-1257 on the recurrence and relapse of acetic acid-induced chronic gastric ulcers in rats]. ( Kobayashi, F; Ohkubo, H; Ohsawa, A; Sekiguchi, H; Taga, F, 1996) |
"Gastric ulcers were induced in young, adult, and aged rats using serosal or mucosal (kissing ulcers) application of acetic acid." | 1.29 | Influence of age on natural and delayed healing of experimentally-induced gastric ulcers in rats. ( Andrews, FJ; O'Brien, PE; Penney, AG, 1996) |
"The effect of a proton pump inhibitor, omeprazole (OPZ), in combination with mouse epidermal growth factor (EGF), on the healing of chronic gastric ulcers induced by acetic acid in submandibular glands removed rats (SMR rat) was investigated." | 1.28 | [Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats]. ( Imai, S; Itoh, M; Joh, T; Takeuchi, T; Yokoyama, Y, 1992) |
"Ebrotidine is a novel H2-receptor antagonist that exhibits both gastroprotective and ulcer-healing properties." | 1.28 | Gastroprotective and ulcer-healing activities of a new H2-receptor antagonist: ebrotidine. ( Brzozowski, T; Konturek, SJ; Majka, J, 1992) |
" Chronic administration of hydrocortisone sodium phosphate resulted in a significant delay of ulcer healing induced by acetic acid." | 1.28 | Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991) |
"Chronic gastric ulcers were produced in male Wistar rats, weighing 180 g, by the application of 100% acetic acid." | 1.28 | Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991) |
" Chronic administration of HC sodium phosphate resulted in a significant delay of ulcer healing induced by acetic acid." | 1.28 | Effects of prostaglandins on hydrocortisone-induced delayed healing of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991) |
"Chronic gastric ulcers were produced in male Wistar rats, weighing 180 g, by serosal application of 100% acetic acid." | 1.28 | Effects of prostaglandins on hydrocortisone-induced delayed healing of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991) |
"Gastric ulcers were induced 5 days after submucosal injection of an acetic acid solution into the stomachs of rats." | 1.28 | Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats. ( Hirose, H; Okabe, S; Takeuchi, K, 1991) |
" This suggests that further stimulation of ulcer healing may be expected if EGF is given with an acid-suppressive agent or with an agent allowing EGF to remain in rat gastric lumen at high concentrations." | 1.28 | Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat. ( Endoh, K; Imai, S; Itoh, M; Iwai, A; Joh, T; Kawai, T; Matsusako, K; Takeuchi, T; Yasue, N; Yokoyama, Y, 1990) |
"Gastric ulcers were induced by subserosal injection of acetic acid, and confirmed by endoscopy on the third day." | 1.28 | Prolylhydroxylase and collagenase activities in the healing of acetic acid-induced gastric ulcers in rats and the effects of cimetidine and elcatonin. ( Komatsu, K; Kurose, I; Maruyama, K; Oda, M; Okazaki, I; Tsuchiya, M, 1989) |
"Gastric ulcers were produced 5 days after injecting 20% acetic acid (0." | 1.28 | Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin. ( Okabe, S; Takeuchi, K; Wang, JY; Yamasaki, S, 1989) |
"Cetraxate was effective in preventing only stress-induced ulcers and had almost no effect on other experimental ulcers." | 1.27 | Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals. ( Aratani, S; Enomoto, H; Kimura, K; Mimura, K; Nomura, A; Ueda, F, 1984) |
"Cimetidine was effective in preventing stress- and acetic acid-induced ulcers but had no significant effect on Shay, indomethacin-induced and histamine-induced ulcers." | 1.27 | Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals. ( Aratani, S; Enomoto, H; Kimura, K; Mimura, K; Nomura, A; Ueda, F, 1984) |
"Chronic gastric ulcers were produced by injection of 20% acetic acid (0." | 1.27 | Effects of trimoprostil on healing and recurrence of acetic acid-induced gastric ulcer in rats. ( Nakamura, K; Umeda, Y, 1986) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 37 (10.00) | 18.7374 |
1990's | 108 (29.19) | 18.2507 |
2000's | 120 (32.43) | 29.6817 |
2010's | 83 (22.43) | 24.3611 |
2020's | 22 (5.95) | 2.80 |
Authors | Studies |
---|---|
Fagundes, FL | 1 |
Pereira, QC | 1 |
Zarricueta, ML | 1 |
Dos Santos, RC | 2 |
Wang, X | 1 |
Wang, S | 1 |
Hou, A | 1 |
Yu, H | 1 |
Zhang, J | 2 |
Zheng, S | 1 |
Zhang, S | 1 |
Lv, J | 1 |
Dong, J | 1 |
Yang, L | 2 |
Kuang, H | 1 |
Jiang, H | 1 |
de Oliveira, BMM | 1 |
Serpa, PZ | 1 |
da Costa Zanatta, ME | 1 |
Aires, BA | 1 |
Steffler, AM | 1 |
Somensi, LB | 4 |
Cury, BJ | 2 |
Dos Santos, AC | 4 |
Venzon, L | 3 |
Boeing, T | 5 |
Mota da Silva, L | 1 |
Roman Junior, WA | 1 |
Meurer, MC | 1 |
Dos Santos França, TC | 1 |
Longo, B | 2 |
Mariott, M | 2 |
Mariano, LNB | 2 |
Cazarin, CA | 1 |
Pereira, LN | 1 |
de Souza, MM | 1 |
da Silva, LM | 10 |
Wang, C | 4 |
Tan, L | 1 |
Liu, J | 5 |
Fu, D | 1 |
Li, P | 2 |
Li, Z | 2 |
Ipek, E | 1 |
Ekren Aşıcı, GS | 1 |
Epikmen, ET | 1 |
Abbak, M | 1 |
Kurt, BK | 1 |
Özsoy, ŞY | 1 |
Tunca, R | 1 |
Jiang, S | 1 |
Zheng, H | 1 |
An, Y | 1 |
Zheng, W | 1 |
Lin, H | 2 |
Wang, G | 1 |
Wang, F | 2 |
Kulikova, OI | 1 |
Stvolinsky, SL | 1 |
Migulin, VA | 1 |
Andreeva, LA | 2 |
Nagaev, IY | 1 |
Lopacheva, OM | 1 |
Kulichenkova, KN | 1 |
Lopachev, AV | 1 |
Trubitsina, IE | 1 |
Fedorova, TN | 1 |
Yuan, Y | 2 |
Pan, H | 1 |
Hsu, AC | 1 |
Chen, J | 1 |
Xing, M | 1 |
Fu, R | 1 |
Liu, Y | 1 |
Wang, P | 1 |
Ma, P | 1 |
Zhu, C | 1 |
Fan, D | 1 |
Garabadu, D | 1 |
Singh, S | 1 |
Gautam, T | 1 |
Ajayi, AF | 1 |
Olaleye, SB | 3 |
Guo, Y | 1 |
Du, Y | 1 |
Xie, L | 1 |
Pu, Y | 1 |
Yuan, J | 1 |
Wang, Z | 2 |
Zhang, T | 1 |
Wang, B | 1 |
Panda, SS | 1 |
Girgis, AS | 1 |
Honkanadavar, HH | 1 |
George, RF | 1 |
Srour, AM | 1 |
Costa, P | 1 |
Meurer, M | 1 |
França, TCS | 1 |
Gouveia, L | 1 |
de Bassi, AC | 1 |
Steimbach, V | 1 |
de Souza, P | 2 |
de Almeida, MO | 1 |
Arruda, C | 1 |
de Andrade, SF | 5 |
Bastos, JK | 1 |
Odukanmi, A | 1 |
Salami, AT | 1 |
Olanrewaju, TR | 1 |
Zalecki, M | 2 |
Juranek, J | 1 |
Pidsudko, Z | 1 |
Mogielnicka-Brzozowska, M | 1 |
Kaleczyc, J | 1 |
Franke-Radowiecka, A | 2 |
Al-Ostoot, FH | 1 |
Grisha, S | 1 |
Mohammed, YHE | 1 |
Vivek, HK | 1 |
Ara Khanum, S | 1 |
Wu, H | 1 |
Wei, M | 1 |
Li, N | 1 |
Lu, Q | 1 |
Shrestha, SM | 1 |
Tan, J | 1 |
Zhang, Z | 3 |
Wu, G | 1 |
Shi, R | 1 |
Bueno, G | 2 |
Chavez Rico, SL | 1 |
Périco, LL | 2 |
Ohara, R | 2 |
Rodrigues, VP | 2 |
Emílio-Silva, MT | 1 |
Assunção, R | 1 |
Machado da Rocha, LR | 1 |
Nunes, DS | 1 |
Besten, MA | 1 |
Heiden, G | 1 |
Lima Camargo, AC | 1 |
Justulin, LA | 1 |
Hiruma-Lima, CA | 4 |
Siwe, GT | 2 |
Maharjan, R | 1 |
Amang, AP | 2 |
Mezui, C | 2 |
Zondegoumba, NE | 1 |
Enow-Orock, GE | 2 |
Choudhary, MI | 1 |
Tan, PV | 2 |
Plywacz, A | 1 |
Antushevich, H | 1 |
Han, T | 1 |
Tang, Y | 1 |
Li, J | 2 |
Xue, B | 1 |
Gong, L | 1 |
Yu, X | 1 |
Liu, C | 1 |
Uchida, M | 8 |
Kobayashi, O | 1 |
Shimizu, K | 2 |
Adeniyi, OS | 1 |
Makinde, OV | 1 |
Friday, ET | 1 |
Magierowski, M | 1 |
Magierowska, K | 1 |
Hubalewska-Mazgaj, M | 1 |
Sliwowski, Z | 1 |
Ginter, G | 1 |
Pajdo, R | 3 |
Chmura, A | 1 |
Kwiecien, S | 4 |
Brzozowski, T | 7 |
Kalayci, M | 1 |
Kocdor, MA | 1 |
Kuloglu, T | 1 |
Sahin, İ | 1 |
Sarac, M | 1 |
Aksoy, A | 1 |
Yardim, M | 1 |
Dalkilic, S | 1 |
Gursu, O | 1 |
Aydin, S | 2 |
Akkoc, RF | 1 |
Ugras, M | 1 |
Artas, G | 1 |
Ozercan, İH | 1 |
Ugur, K | 1 |
Pinz, MP | 1 |
Reis, AS | 1 |
de Oliveira, RL | 1 |
Voss, GT | 1 |
Vogt, AG | 1 |
Sacramento, MD | 1 |
Roehrs, JA | 1 |
Alves, D | 1 |
Luchese, C | 1 |
Wilhelm, EA | 1 |
Wang, Y | 2 |
Wang, SL | 1 |
Zhang, JY | 1 |
Song, XN | 1 |
Zhang, ZY | 1 |
Li, JF | 1 |
Li, S | 2 |
Emakoua, J | 1 |
Mbah, G | 1 |
Nkwengoua, EZ | 1 |
Zapata-Morales, JR | 1 |
Alonso-Castro, ÁJ | 1 |
Granados-Soto, V | 1 |
Sánchez-Enriquez, S | 1 |
Isiordia-Espinoza, MA | 1 |
Hamdi, A | 1 |
Majouli, K | 1 |
Abdelhamid, A | 1 |
Marzouk, B | 1 |
Belghith, H | 1 |
Chraief, I | 1 |
Bouraoui, A | 1 |
Marzouk, Z | 1 |
Heyden, YV | 1 |
Kolgazi, M | 1 |
Ozdemir-Kumral, ZN | 1 |
Cantali-Ozturk, C | 1 |
Demirci, EK | 1 |
Yuksel, M | 3 |
Sirvanci, S | 1 |
Yegen, BC | 5 |
Dos Santos, CBR | 1 |
da Silva Ramos, R | 1 |
Ortiz, BLS | 1 |
da Silva, GM | 1 |
Giuliatti, S | 1 |
Balderas-Lopez, JL | 1 |
Navarrete, A | 1 |
Carvalho, JCT | 1 |
Navarro, L | 1 |
Rosell, G | 1 |
Sánchez, S | 1 |
Boixareu, N | 1 |
Pors, K | 1 |
Pouplana, R | 1 |
Campanera, JM | 1 |
Pujol, MD | 1 |
Yu, Y | 2 |
Cai, Q | 2 |
Jia, TZ | 2 |
Nunes, VVA | 1 |
Camargo, ACL | 1 |
Justulin Júnior, LA | 1 |
Steimbach, VMB | 1 |
da Rocha, LRM | 1 |
Vilegas, W | 5 |
Dos Santos, C | 1 |
Almeida, GVB | 1 |
Arunachalam, K | 1 |
Balogun, SO | 4 |
Pavan, E | 2 |
Ascêncio, SD | 2 |
Soares, IM | 2 |
Zanatta, AC | 1 |
Macho, A | 1 |
Oliveira Martins, DT | 1 |
Bang, BW | 1 |
Park, D | 1 |
Kwon, KS | 1 |
Lee, DH | 1 |
Jang, MJ | 1 |
Park, SK | 1 |
Kim, JY | 1 |
Yoshioka, T | 1 |
Fukuda, A | 1 |
Araki, O | 1 |
Ogawa, S | 1 |
Hanyu, Y | 1 |
Matsumoto, Y | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Single Arm, Open-label Pilot Trial Examining the Effects of Pau d' Arco on Primary Dysmenorrhea in Reproductive Age Women[NCT04245540] | Early Phase 1 | 12 participants (Actual) | Interventional | 2019-07-30 | Completed | ||
Effects of Lavender Aromatherapy and Cold Application on Pain During Drain Removal[NCT04798040] | 121 participants (Actual) | Interventional | 2021-09-01 | Completed | |||
Elderly Patients With Dementia in the Department of Acute Geriatrics: Pilot Study, Monocentric, Randomized Use of Aromatherapy as a Complementary Treatment to Psychopharmacotherapy in Psychological Disorders and BPSD Behavior[NCT03662360] | 32 participants (Actual) | Interventional | 2018-05-20 | Completed | |||
A Randomized Prospective Placebo-Controlled Study of the Effects of Lavender Aromatherapy on Preoperative Anxiety in Breast Surgery Patients[NCT01837966] | 93 participants (Actual) | Interventional | 2013-01-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"The Neuropsychiatric Inventory - Nursing Home Version (NPI-NH) test will characterize the neuropsychiatric and psychopathological symptoms of patients affected by dementia.~Events as delirium, anxiety, depression, etc. will be recorded by the frequency (from 0, absence, to 4, high frequency) and the seriousness (from 0, absence, to 3, high). The total score of the NPI-NH is given by the frequency x (multiply) seriousness (total score for each event has a range from 0 to 12). The patient final score will be given by the sum of the score of the 12 events. For each patient will be given a total score from 0 to 144.~NPI NH score has been collected in both control and aromatherapy groups at T1 and T3, in patients who needed and who did not needed Pro Re Nata." (NCT03662360)
Timeframe: Time 1 (baseline) and Time 3 (day 7)
Intervention | score on a scale (Mean) | ||
---|---|---|---|
T1 NPI score in patients do not need Pro Re Nata | T3 NPI score in patients needed Pro Re Nata | T3 NPI score in patients do not need Pro Re Nata | |
GROUP A - Control Group | 21.81 | 32.87 | 20.00 |
GROUP B - Aromatherapy Group | 25.93 | 16.5 | 7.25 |
NPI-NH assess the psychological distress in physicians, nurses and nursing assistants who managed the patients. It has a score from 0 (no discomfort) to score of 5 (extreme discomfort). The psychological distress is measured for each of the 12 events in the NPI-NH scale, for a total score from 0 to 60. (NCT03662360)
Timeframe: Time 1 (baseline) and Time 3 (day 7)
Intervention | score on a scale (Mean) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
T1 NPI NH physicians in pts with PRN | T1 NPI NH physicians in pts without PRN | T1 NPI NH nurses in pts with PRN | T1 NPI NH nurses in pts without PRN | T1 NPI NH nursing assistants in pts with PRN | T1 NPI NH nursing assistants in pts without PRN | T3 NPI NH physician in pts with PRN | T3 NPI NH physician in pts without PRN | T3 NPI NH nurses in pts with PRN | T3 NPI NH nurses in pts without PRN | T3 NPI NH nursing assistants in pts with PRN | T3 NPI NH nursing assistants in pts without PRN | |
GROUP A - Control Group | 4.19 | 1.60 | 9.63 | 6.40 | 11.00 | 7.10 | 6.00 | 3.20 | 12.00 | 9.30 | 13.19 | 9.90 |
GROUP B - Aromatherapy Group | 5.64 | 4.13 | 11.64 | 10.13 | 12.21 | 10.88 | 2.64 | 0.88 | 5.79 | 4.25 | 5.93 | 4.38 |
We hoped to show that lavender aroma therapy reduces preoperative anxiety in patients undergoing breast. The Trait subscale (STAI-TRAID) of the Spielberger State-Trait Anxiety Inventory was administered before and after 10 minutes of aromatherapy treatment pre-surgery. The TRAIT subscale contains 20 questions scored on a Likert scale from 1-4; item scores are summed for a total score ranging from 20 to 80, with higher scores indicating higher anxiety. Change in anxiety was calculated as the score pre-aromatherapy minus the score post-aromatherapy. Higher positive change scores indicate greater reductions in anxiety. (NCT01837966)
Timeframe: 20 minutes before surgery (pre aromatherapy) and 10 minutes before surgery (post aromatherapy)
Intervention | units on a scale (Mean) |
---|---|
Lavender Oil | 0.89 |
Placebo | .74 |
1 trial available for acetic acid and Gastric Ulcer
Article | Year |
---|---|
Are probiotics effective in the treatment of fungal colonization of the gastrointestinal tract? Experimental and clinical studies.
Topics: Acetic Acid; Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antif | 2006 |
369 other studies available for acetic acid and Gastric Ulcer
Article | Year |
---|---|
Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation.
Topics: Acetic Acid; Animals; Anthocyanins; Antioxidants; Biomarkers; Cyclooxygenase 1; Disease Models, Anim | 2021 |
The effect of anti-alcoholic gastric ulcer before and after vinegar-processed Yuanhu Zhitong prescription based on spectral-effect relationship.
Topics: Acetic Acid; Chromatography, Liquid; Drugs, Chinese Herbal; Eosine Yellowish-(YS); Hematoxylin; Huma | 2022 |
Gastroprotective and gastric healing effects of the aqueous extract of Casearia sylvestris in rodents: Ultrasound, histological and biochemical analyzes.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Casearia; Ethanol; Female; Gastric Mucosa; Mice; Mucins; Ni | 2022 |
Geraniol accelerates the gastric healing, minimizes ulcers recurrence, and reduces anxiolytic-like behavior in ulcerated rodents by oral or inhaled route.
Topics: Acetic Acid; Acyclic Monoterpenes; Animals; Anti-Anxiety Agents; Anti-Ulcer Agents; Gastric Mucosa; | 2022 |
Integrated Metabolomics and Network Pharmacology to Decipher the Latent Mechanisms of Protopanaxatriol against Acetic Acid-Induced Gastric Ulcer.
Topics: Acetic Acid; Animals; Biomarkers; Epidermal Growth Factor; Ginsenosides; Interleukin-6; Metabolomics | 2022 |
Evaluation of Acetic Acid-Induced Chronic Gastric Ulcer Healing by Propionyl-L-Carnitine Administration.
Topics: Acetic Acid; Animals; Cyclooxygenase 2; Epidermal Growth Factor; Rats; Rats, Wistar; Stomach Ulcer; | 2023 |
Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats.
Topics: Acetic Acid; Animals; Gastrointestinal Microbiome; Male; Metabolome; Rats; Rats, Wistar; Stomach Ulc | 2024 |
A new derivative of acetylsalicylic acid and carnosine: synthesis, physical and chemical properties, biological activity.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Carnosine; Erythrocytes; Hemolysis; | 2020 |
Protective Effect of Ocotillol, the Derivate of Ocotillol-Type Saponins in
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Endothelin-1; Ginsenosides; Male; | 2020 |
Human-like collagen promotes the healing of acetic acid-induced gastric ulcers in rats by regulating NOS and growth factors.
Topics: Acetic Acid; Animals; Cell Line; Cell Movement; Cell Proliferation; Collagen; Drug Administration Sc | 2020 |
Topics: Acetic Acid; Animals; Catalase; Gastric Mucosa; Glutathione; Male; Manilkara; Plant Bark; Plant Extr | 2021 |
Immunohistochemical Studies of Age-Related Changes in Cell Proliferation and Angiogenesis during the Healing of Acetic Acid-Induced Gastric Ulcers in Rats.
Topics: Acetic Acid; Age Factors; Animals; Biomarkers; Cell Proliferation; ErbB Receptors; Factor VIII; Immu | 2020 |
Effects of Paeonol and Gastroretention Tablets of Paeonol on Experimental Gastric Ulcers and Intestinal Flora in Rats.
Topics: Acetic Acid; Acetophenones; Animals; Antioxidants; Catalase; Gastric Acid; Gastric Mucosa; Gastroint | 2020 |
Synthesis of new ibuprofen hybrid conjugates as potential anti-inflammatory and analgesic agents.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygena | 2020 |
Gastric healing effect of p-coumaric acid isolated from Baccharis dracunculifolia DC on animal model.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Baccharis; Catalase; Cell Line; Cell Proliferation; Cell Su | 2021 |
Exposure to Mosquito Coil Smoke Delays Healing of Acetic Acid Induced Gastric Ulcer in Male Wistar Rats.
Topics: Acetic Acid; Animals; Culicidae; Gastric Mucosa; Insecticides; Male; Oxidative Stress; Rats, Wistar; | 2020 |
Inferior vagal ganglion galaninergic response to gastric ulcers.
Topics: Acetic Acid; Animals; Galanin; Ganglia, Parasympathetic; Receptors, Galanin; RNA, Messenger; Stomach | 2020 |
Molecular docking and synthesis of caffeic acid analogous and its anti-inflammatory, analgesic and ulcerogenic studies.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Carrageena | 2021 |
Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157.
Topics: Acetic Acid; Administration, Oral; Animals; Clopidogrel; Injections, Intraperitoneal; Male; Peptide | 2020 |
The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Baccharis; Brazil; Caspases; Cyclooxygenase 1; Cyclooxygena | 2021 |
Eremomastax speciosa (Hochst.) Cufod. counteracts the delaying effect of indomethacin on Helicobacter pylori-associated chronic gastric ulcers healing.
Topics: Acanthaceae; Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Disease Models, Animal; Dose-Res | 2021 |
Cocaine and Amphetamine Regulated Transcript (CART) Expression Changes in the Stomach Wall Affected by Experimentally Induced Gastric Ulcerations.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Enteric Nervous System; Female; Myenteric Plexus; Nerve | 2021 |
Nitric oxide donor protects against acetic acid-induced gastric ulcer in rats via S-nitrosylation of TRPV1 on vagus nerve.
Topics: Acetic Acid; Animals; Dose-Response Relationship, Drug; Membrane Potentials; Neurons; Nitric Oxide; | 2017 |
Gastric emptying after artificial ulceration in rats: differences due to the site of the ulcer and the effects of prokinetic drugs.
Topics: Acetic Acid; Animals; Benzamides; Breath Tests; Dose-Response Relationship, Drug; Gastric Emptying; | 2017 |
Effects of quinine on gastric ulcer healing in Wistar rats.
Topics: Acetic Acid; Animals; Cinchona; Gastric Mucosa; Inflammation; Lipid Peroxidation; Male; Mucus; Oxida | 2017 |
Carbon monoxide released from its pharmacological donor, tricarbonyldichlororuthenium (II) dimer, accelerates the healing of pre-existing gastric ulcers.
Topics: Acetic Acid; Animals; Carbon Monoxide; Cyclooxygenase 2; Epidermal Growth Factor; ErbB Receptors; Ga | 2017 |
Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Disease Models, Animal; Dose-Response Relationship, Drug; G | 2017 |
7-Chloro-4-phenylsulfonyl quinoline, a new antinociceptive and anti-inflammatory molecule: Structural improvement of a quinoline derivate with pharmacological activity.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Croton Oil; Edema; Hot Temperature; Huma | 2017 |
Anti-ulcer and anti-Helicobacter pylori potentials of the ethyl acetate fraction of Physalis alkekengi L. var. franchetii (Solanaceae) in rodent.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Ul | 2018 |
Healing and Antisecretory Effects of Aqueous Extract of
Topics: Acanthaceae; Acetic Acid; Animals; Antioxidants; Disease Models, Animal; Gastric Mucosa; Humans; Ind | 2017 |
Assessment of the antinociceptive and ulcerogenic activity of the tapentadol-diclofenac combination in rodents.
Topics: Acetic Acid; Analgesics; Animals; Diclofenac; Dose-Response Relationship, Drug; Drug Synergism; Male | 2018 |
Pharmacological activities of the organic extracts and fatty acid composition of the petroleum ether extract from Haplophyllum tuberculatum leaves.
Topics: Acetic Acid; Alkanes; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carrageenan; | 2018 |
Anti-inflammatory effects of nesfatin-1 on acetic acid-induced gastric ulcer in rats: involvement of cyclo-oxygenase pathway.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Calcium-Binding Proteins; Cyclooxygenase 1; Cyclooxy | 2017 |
Oil from the fruits of Pterodon emarginatus Vog.: A traditional anti-inflammatory. Study combining in vivo and in silico.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Croton Oil; Cyclooxygenase | 2018 |
Synthesis and biological properties of aryl methyl sulfones.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carrageenan; Dimet | 2018 |
[Study on Variation of Gastroprotective Effect of Atractylodes lancea Rhizome Before and After Processing].
Topics: Acetic Acid; Animals; Atractylodes; Drugs, Chinese Herbal; Rats; Rhizome; Stomach Ulcer; Trefoil Fac | 2016 |
Sex-specific effects of
Topics: Acetic Acid; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Eugenia; Female; Gastric | 2018 |
Chemical characterization and evaluation of gastric antiulcer properties of the hydroethanolic extract of the stem bark of Virola elongata (Benth.) Warb.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Ethanol; Female; Mice; Myristicaceae; Phytochemicals; Phyto | 2019 |
BST-104, a Water Extract of Lonicera japonica, Has a Gastroprotective Effect via Antioxidant and Anti-Inflammatory Activities.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Chlorogenic Acid; C | 2019 |
Bmi1 marks gastric stem cells located in the isthmus in mice.
Topics: Acetic Acid; Animals; Biomarkers; Cell Differentiation; Cell Lineage; Cell Proliferation; Disease Mo | 2019 |
(-)-Myrtenol accelerates healing of acetic acid-induced gastric ulcers in rats and in human gastric adenocarcinoma cells.
Topics: Acetic Acid; Adenocarcinoma; Animals; Bicyclic Monoterpenes; Cell Line, Tumor; Cell Movement; Cell P | 2019 |
Evaluation of the antiulcer activity of the aqueous stem bark extract of Balanites aegyptiaca L Delile in Wistar rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Balanites; Ethanol; Indomethacin; Ligation; Male; Phytother | 2019 |
Hesperidin, a citrus flavanone glycoside, accelerates the gastric healing process of acetic acid-induced ulcer in rats.
Topics: Acetic Acid; Animals; Catalase; Drug Administration Schedule; Flavanones; Gastric Mucosa; Glutathion | 2019 |
Antiulcer activity of Cyperus alternifolius in relation to its UPLC-MS metabolite fingerprint: A mechanistic study.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Chromatography, Liquid; | 2019 |
Protective effect of polysaccharides from Radix Hedysari on gastric ulcers induced by acetic acid in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Cell Movement; Cell | 2019 |
The probiotic mixture VSL#3 accelerates gastric ulcer healing by stimulating vascular endothelial growth factor.
Topics: Acetic Acid; Animals; Cytokines; DNA Primers; Dose-Response Relationship, Drug; Gene Expression Regu | 2013 |
Role of gastric mucus secretion, oxinitrergic system and sulfhydryl groups on the gastroprotection elicited by Polygala cyparissias (Polygalaceae) in mice.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Chronic Disease; Ethanol; Gastric Mucosa; Helicobacter pylo | 2013 |
[Study on efficacy and mechanism of weiyangning pills against experimental gastric ulcer].
Topics: Acetic Acid; Animals; Aspirin; Dinoprostone; Drugs, Chinese Herbal; Epidermal Growth Factor; Female; | 2013 |
Arbortristoside-A and 7-O-trans-cinnamoyl-6β-hydroxyloganin isolated from Nyctanthes arbortristis possess anti-ulcerogenic and ulcer-healing properties.
Topics: Acetic Acid; Alcohols; Animals; Anti-Ulcer Agents; Cinnamates; Disease Models, Animal; Female; Irido | 2013 |
Desvenlafaxine succinate ameliorates visceral hypersensitivity but delays solid gastric emptying in rats.
Topics: Acetic Acid; Administration, Oral; Adrenergic Uptake Inhibitors; Animals; Cyclohexanols; Desvenlafax | 2013 |
NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4(+)VEGFR1(+) cells to the ulcer granulation tissues.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemokine CXCL12; Enzyme Pre | 2013 |
Zinc(II)-curcumin accelerates the healing of acetic acid-induced chronic gastric ulcers in rats by decreasing oxidative stress and downregulation of matrix metalloproteinase-9.
Topics: Acetic Acid; Animals; Curcumin; Disease Models, Animal; Down-Regulation; Gastric Mucosa; Glutathione | 2013 |
The acid-secreting parietal cell as an endocrine source of Sonic Hedgehog during gastric repair.
Topics: Acetic Acid; Animals; Cell Line; Epithelial Cells; Female; Gastric Mucosa; Gene Expression Regulatio | 2013 |
High-mobility group box 1 inhibits gastric ulcer healing through Toll-like receptor 4 and receptor for advanced glycation end products.
Topics: Acetic Acid; Animals; Antibodies; Gastric Mucosa; Gene Expression Regulation; Glycation End Products | 2013 |
Experimental healing of preexisting gastric ulcers induced by hormones controlling food intake ghrelin, orexin-A and nesfatin-1 is impaired under diabetic conditions. A key to understanding the diabetic gastropathy?
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Calcium-Binding Proteins; Diabetes Mellitus, Experimental; | 2013 |
Estrogen alleviates acetic acid-induced gastric or colonic damage via both ERα- and ERβ-mediated and direct antioxidant mechanisms in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Movement; Colitis; Cytokines; Est | 2014 |
Evaluation of the gastroprotective activity of the extracts, fractions, and pure compounds obtained from aerial parts of Rubus imperialis in different experimental models.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Ethanol; Indometha | 2014 |
Rhamnogalacturonan from Acmella oleracea (L.) R.K. Jansen: gastroprotective and ulcer healing properties in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Asteraceae; Body Weight; Cell Proliferation; | 2014 |
Metabolomics coupled with multivariate data and pathway analysis on potential biomarkers in gastric ulcer and intervention effects of Corydalis yanhusuo alkaloid.
Topics: Acetic Acid; Alkaloids; Animals; Base Sequence; Biomarkers; Chromatography, High Pressure Liquid; Co | 2014 |
Evaluation of the morphological changes of gastric mucosa induced by a low concentration of acetic acid using a rat model.
Topics: Acetic Acid; Animals; Burns, Chemical; Caustics; Fibroblasts; Forensic Pathology; Gastric Mucosa; Ma | 2014 |
Motility and chemotaxis mediate the preferential colonization of gastric injury sites by Helicobacter pylori.
Topics: Acetic Acid; Animals; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Indicators and R | 2014 |
Mechanisms involved in the gastroprotective activity of Celtis iguanaea (Jacq.) Sargent on gastric lesions in mice.
Topics: Acetic Acid; Adrenergic alpha-2 Receptor Antagonists; Animals; Anti-Ulcer Agents; Cyclooxygenase Inh | 2014 |
Synthesis, hydrolysis kinetics and pharmacological evaluation of aceclofenac prodrugs.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2015 |
Antiulcerogenic activity of Carica papaya seed in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carica; Ethanol; F | 2015 |
Terminalia catappa L.: a medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Caribbean Region; Disease Models, An | 2015 |
Comparison of the anti-ulcer activity between the crude and bran-processed Atractylodes lancea in the rat model of gastric ulcer induced by acetic acid.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Atractylodes; Dietary Fiber; Dinoprostone; Disease M | 2015 |
Evidence of gastric ulcer healing activity of Maytenus robusta Reissek: In vitro and in vivo studies.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Brazil; Catalase; Cell Line, Tumor; Cell Survival; Female; | 2015 |
Evaluation of the safety, gastroprotective activity and mechanism of action of standardised leaves infusion extract of Copaifera malmei Harms.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Brazil; Catalase; Cell Survival; CHO Cells; Cricetulus; Eth | 2015 |
Gastroprotective effects of thymol on acute and chronic ulcers in rats: The role of prostaglandins, ATP-sensitive K(+) channels, and gastric mucus secretion.
Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relation | 2016 |
Healing mechanisms of the hydroalcoholic extract and ethyl acetate fraction of green tea (Camellia sinensis (L.) Kuntze) on chronic gastric ulcers.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Camellia sinensis; Ethanol; Female; Gastric Acid; | 2016 |
Gastroprotective potential of Pentahydroxy flavone isolated from Madhuca indica J. F. Gmel. leaves against acetic acid-induced ulcer in rats: The role of oxido-inflammatory and prostaglandins markers.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Biomarkers; Cyclooxygenase 2; Gastric Mucosa; Glutathione; | 2016 |
Protective Effect of Cod (Gadus macrocephalus) Skin Collagen Peptides on Acetic Acid-Induced Gastric Ulcer in Rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Collagen; Gadiformes; Gastric Mucosa; HSP70 H | 2016 |
Glyprolines exert protective and repair-promoting effects in the rat stomach: potential role of the cytokine GRO/CINC-1.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cells, Cultured; Chemokine CXCL1; Epithelial Cells; Gastric | 2016 |
Diminazene aceturate, an angiotensin-converting enzyme II activator, prevents gastric mucosal damage in mice: Role of the angiotensin-(1-7)/Mas receptor axis.
Topics: Acetic Acid; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, An | 2016 |
Hydroethanolic extract of Baccharis trimera promotes gastroprotection and healing of acute and chronic gastric ulcers induced by ethanol and acetic acid.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Baccharis; Cytoprotection; Disease Models, An | 2016 |
Rational Design and Synthesis of Biologically Active Disubstituted 2(3H) Furanones and Pyrrolone Derivatives as Potent and Safer Non Steroidal Anti-inflammatory Agents.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Female; Furans; Male | 2016 |
Piper umbellatum L.: A medicinal plant with gastric-ulcer protective and ulcer healing effects in experimental rodent models.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Catalase; Chronic Dis | 2016 |
Beta-cyclodextrin enhanced gastroprotective effect of (-)-linalool, a monoterpene present in rosewood essential oil, in gastric lesion models.
Topics: Acetic Acid; Acyclic Monoterpenes; Animals; Anti-Ulcer Agents; Antioxidants; beta-Cyclodextrins; Cyt | 2016 |
The direct comparison of health and ulcerated stomach tissue: a multiple probe microdialysis sampling approach.
Topics: Acetic Acid; Animals; Area Under Curve; Caffeine; Calibration; Chromatography, High Pressure Liquid; | 2008 |
Characterization of eltenac and novel COX-2 selective thiopheneacetic acid analogues in vitro and in vivo.
Topics: Acetic Acid; Aniline Compounds; Animals; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibit | 2008 |
Acetic acid induced ulceration in rats is not affected by infection with Hymenolepis diminuta.
Topics: Acetic Acid; Animals; Disease Models, Animal; Hymenolepiasis; Hymenolepis diminuta; Male; Rats; Rats | 2009 |
The role of sensory C-fibers in response of vagal afferent stimulation by gastric distension in rats with experimental chronic gastric ulcer.
Topics: Acetic Acid; Afferent Pathways; Animals; Capsaicin; Chronic Disease; Disease Models, Animal; Gastric | 2008 |
Effects of pantoprazole on ulcer healing delay associated with NSAID treatment.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroid | 2009 |
Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol.
Topics: Acetic Acid; Administration, Oral; Aging; alpha-Tocopherol; Animals; Anti-Ulcer Agents; Antioxidants | 2008 |
Synthesis, analgesic and anti inflammatory activities of some new fenamate analogues.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, | 2008 |
Synthesis and evaluation of antiinflammatory and analgesic activities of a novel series of coumarin Mannich bases.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Coumarins; Drug Evaluation | 2008 |
Alpha-lipoic acid improves acetic acid-induced gastric ulcer healing in rats.
Topics: Acetic Acid; Animals; Antioxidants; DNA Fragmentation; Female; Gastric Mucosa; Glutathione; Luminesc | 2009 |
Cytokine signalling by gp130 regulates gastric mucosal healing after ulceration and, indirectly, antral tumour progression.
Topics: Acetic Acid; Animals; Cell Proliferation; Cytokine Receptor gp130; Disease Progression; Fibrosis; Ga | 2009 |
Synergy between enzyme inhibitors of fatty acid amide hydrolase and cyclooxygenase in visceral nociception.
Topics: Acetic Acid; Amidohydrolases; Animals; Benzamides; Carbamates; Cyclooxygenase Inhibitors; Diclofenac | 2009 |
Novel 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines: synthesis, characterization, and evaluation of analgesic/anti-inflammatory, antioxidant activities.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carrageenan | 2009 |
Treatment with ghrelin accelerates the healing of acetic acid-induced gastric and duodenal ulcers in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cell Proliferation; Chronic Disease; DNA; Dose-Response Rel | 2009 |
Protective and therapeutic effects of resveratrol on acetic acid-induced gastric ulcer.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Female; Glutathione; Irritants; Lipid | 2009 |
Gastroprotective constituents of Salvia officinalis L.
Topics: Abietanes; Acetic Acid; Animals; Anti-Ulcer Agents; Ethanol; Female; Gastric Mucosa; Phytotherapy; P | 2009 |
In vitro and in vivo anti-Helicobacter pylori activity of Calophyllum brasiliense Camb.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Brazil; Calophyllum; Dinoprostone; D | 2009 |
Synthesis of novel 1,3,4-oxadiazole derivatives and their biological properties.
Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Carrageenan; Dise | 2009 |
[Therapeutic effect of astaxanthin on acetic acid-induced gastric ulcer in rats].
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Catalase; Gastric Mucosa; Glutathione Peroxid | 2009 |
Effect of methanolic extract of Pongamia pinnata Linn seed on gastro-duodenal ulceration and mucosal offensive and defensive factors in rats.
Topics: Acetic Acid; Animals; Aspirin; Catalase; Chromatography, Thin Layer; Cold Temperature; Duodenal Ulce | 2009 |
Role of modulation of vascular endothelial growth factor and tumor necrosis factor-alpha in gastric ulcer healing in diabetic rats.
Topics: Acetic Acid; Animals; Anticholesteremic Agents; Diabetes Mellitus, Experimental; Free Radical Scaven | 2010 |
[Influence of honey, royal jelly and propolis on accelerating acetate healing of experimental gastric ulcers in rats].
Topics: Acetic Acid; Animals; Anti-Infective Agents; Chronic Disease; Disease Models, Animal; Fatty Acids; H | 2009 |
Synthesis of new 2,3-dihydroquinazolin-4(1H)-one derivatives for analgesic and anti-inflammatory evaluation.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Chalcones; Drug Evaluation, | 2010 |
Effects of lansoprazole on the expression of VEGF and cellular proliferation in a rat model of acetic acid-induced gastric ulcer.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Anti-Ulcer Agents; Cell Cycle; Cell P | 2010 |
Enhancement of gastric ulcer healing and angiogenesis by cochinchina Momordica seed extract in rats.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Factor VIII; Male; Momordica; Neovasc | 2010 |
Altered expression of a putative progenitor cell marker DCAMKL1 in the rat gastric mucosa in regeneration, metaplasia and dysplasia.
Topics: Acetic Acid; Animals; Biomarkers; Cell Proliferation; Disease Models, Animal; Doublecortin Protein; | 2010 |
Role of microsomal prostaglandin E synthase-1 in the facilitation of angiogenesis and the healing of gastric ulcers.
Topics: Acetic Acid; Analysis of Variance; Animals; Cyclooxygenase 2; Gastric Mucosa; Immunoenzyme Technique | 2010 |
Yogurt containing Lactobacillus gasseri OLL 2716 (LG21 yogurt) accelerated the healing of acetic acid-induced gastric ulcer in rats.
Topics: Acetic Acid; Animals; Dinoprostone; Gamma Rays; Gastric Mucosa; Hydrochloric Acid; Lactobacillus; Pr | 2010 |
[Investigation of therapeutic mechanism of Weiweifang on experimental gastric ulcer in rats viewing from metabonomics].
Topics: Acetic Acid; Amino Acids; Animals; Drugs, Chinese Herbal; Fatty Acids; Gas Chromatography-Mass Spect | 2010 |
Ginger extract and polaprezinc exert gastroprotective actions by anti-oxidant and growth factor modulating effects in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Carnosine; Chemokines; Cytokines; Cytoprotect | 2010 |
Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Biomarkers; Cisapride; Disease Models | 2011 |
Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae).
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Bicyclic Monoterpenes; Brazil; Bridged Bicyclo Compounds; C | 2011 |
Design and synthesis of certain mesoionic sydnonyl styrylketones as potential nonsteroidal antiinflammatory agents.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Drug Design; Edema; Fema | 2011 |
Gastroprotective and ulcer-healing mechanisms of ellagic acid in experimental rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cytokines; Dinoprostone; Ellagic Acid; Ethanol; Female; Gas | 2011 |
Fluorine bearing sydnones with styryl ketone group: synthesis and their possible analgesic and anti-inflammatory activities.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Croton Oil; Edema; Female; | 2012 |
Stimulation of gastric ulcer healing by heat shock protein 70.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; HSP70 Heat-Shock Proteins; Male; Mice; Mice, Inbred C57BL; | 2011 |
Pharmacological profile of FK881(ASP6537), a novel potent and selective cyclooxygenase-1 inhibitor.
Topics: Acetic Acid; Animals; Arthritis, Experimental; Carrageenan; CHO Cells; Cricetinae; Cricetulus; Cyclo | 2011 |
Activity of DBXX granules on anti-gastric ulcer and decreasing the side effect of chemotherapy in S180 tumor-bearing mice.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antineoplastic Agents; Cyclophosphamide; Dose-Response Rela | 2011 |
Role of activation of 5'-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats.
Topics: Acetic Acid; Animals; Blood Glucose; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Experi | 2011 |
Mechanisms of action underlying the gastric antiulcer activity of the Rhizophora mangle L.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Epidermal | 2012 |
Isolation of active constituents from cherry laurel (Laurocerasus officinalis Roem.) leaves through bioassay-guided procedures.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Biological Assay; Capilla | 2012 |
Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model.
Topics: Acetic Acid; Adenocarcinoma; Administration, Topical; Animals; Antineoplastic Agents; Disease Models | 2012 |
Antiulcerogenic effect of Croton urucurana Baillon bark.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Croton; Disease Models, Animal; Ethanol; Female; Gastric Ac | 2012 |
Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors.
Topics: 1-Deoxynojirimycin; Acetic Acid; Animals; Apoptosis; Disease Models, Animal; Enzyme Inhibitors; Fumo | 2013 |
Antiulcer effect of bark extract of Tabebuia avellanedae: activation of cell proliferation in gastric mucosa during the healing process.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cell Proliferation; Female; Gastric Mucosa; Mucus; Phenols; | 2013 |
Ethanolic extract of roots from Arctium lappa L. accelerates the healing of acetic acid-induced gastric ulcer in rats: Involvement of the antioxidant system.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Arctium; Capillary Permeability; Ethanol; Fem | 2013 |
Evaluation of antiulcer activity and mechanism of action of methanol stem bark extract of Lafoensia pacari A. St.-Hil. (Lytraceae) in experimental animals.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Brazil; Ethanol; Gastrointestinal Transit; Indomethacin; In | 2012 |
[Effect of Pongamia pinnata root flavonoids on the quality of ulcer healing and expression of EGF and TGF-alpha in the rat model of gastric ulcer induced by acetic acid].
Topics: Acetic Acid; Animals; Epidermal Growth Factor; Female; Flavonoids; Gastric Mucosa; Male; Millettia; | 2012 |
Evaluation of the analgesic and anti-inflammatory activities of some thiazolo[4,5-d]pyrimidines.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan | 2002 |
[Deficit of glucocorticoid production in rats aggravates ulcerogenic effects of stimuli of various modality and intensity].
Topics: Acetic Acid; Adrenalectomy; Animals; Aspirin; Corticosterone; Ethanol; Glucocorticoids; Hormone Repl | 2002 |
Mechanism of the antiulcerogenic effect of IL-11 on acetic acid-induced gastric ulcer in rats.
Topics: Acetic Acid; Animals; Humans; Interleukin-11; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, | 2002 |
Rebamipide prevents delay of acetic acid-induced gastric ulcer healing caused by Helicobacter pylori infection in Mongolian gerbils.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Apoptosis; Cell Division; Epithelium; Gerbillinae; | 2002 |
Models of gastric hyperalgesia in the rat.
Topics: Acetic Acid; Animals; Avoidance Learning; Behavior, Animal; Catheterization; Disease Models, Animal; | 2002 |
Oligoethylene ester derivatives of ketoprofen, naproxen and diclofenac as oral prodrugs: a pharmacological evaluation.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Edema; Ester | 2002 |
Antinociceptive and gastroprotective effects of diterpenes from the flower buds of Egletes viscosa.
Topics: Acetic Acid; Analgesics; Animals; Anti-Ulcer Agents; Asteraceae; Diterpenes; Dose-Response Relations | 2002 |
Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Cyclooxygenase 2; Gastric Mucosa; Glyceraldehyde-3 | 2003 |
Effects of hydrochloric, acetic, butyric, and propionic acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses.
Topics: Acetic Acid; Animals; Butyric Acid; Culture Techniques; Fatty Acids, Volatile; Female; Gastric Mucos | 2003 |
Synthesis of ibuprofen heterocyclic amides and investigation of their analgesic and toxicological properties.
Topics: Acetic Acid; Administration, Oral; Amides; Analgesics, Non-Narcotic; Animals; Ibuprofen; Injections, | 2003 |
Nerve growth factor and gastric hyperalgesia in the rat.
Topics: Acetic Acid; Animals; Antibodies; Electromyography; Enzyme-Linked Immunosorbent Assay; Hyperalgesia; | 2003 |
Oleanolic acid promotes healing of acetic acid-induced chronic gastric lesions in rats.
Topics: Acetic Acid; Analysis of Variance; Animals; Gastric Mucosa; Histamine H2 Antagonists; Male; Oleanoli | 2003 |
Rebamipide binds to iNOS-positive cells in acetic acid-treated but not in ethanol-treated rat gastric mucosa.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Binding Sites; Ethanol; Gastric Mucosa; Indicators | 2003 |
Transforming growth factor-alpha directly augments histidine decarboxylase and vesicular monoamine transporter 2 production in rat enterochromaffin-like cells.
Topics: Acetic Acid; Animals; Blotting, Northern; Cell Separation; Cells, Cultured; Enterochromaffin Cells; | 2004 |
Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats.
Topics: Acetic Acid; Animals; Dinoprostone; Disease Models, Animal; Drug Administration Schedule; Fibrosis; | 2003 |
Temporal increase in the gastric colonization of Helicobacter pylori after healing of acetic acid-induced gastric ulcer in a miniature pig.
Topics: Acetic Acid; Animals; Colony Count, Microbial; Helicobacter Infections; Helicobacter pylori; Male; S | 2003 |
Gastroprotective and anti-inflammatory effects of resin from Protium heptaphyllum in mice and rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Brazil; Burseraceae; Capillary Pe | 2004 |
Roles of inducible nitric oxide synthase in the development and healing of experimentally induced gastric ulcers.
Topics: Acetic Acid; Animals; Apoptosis; Cell Division; Gene Expression; Male; Mice; Mice, Inbred C57BL; Neo | 2003 |
[Deficiency of glucocorticoid production delays the healing of acute gastric mucosal erosion and chronic ulcers in rats].
Topics: Acetic Acid; Adrenalectomy; Animals; Chronic Disease; Corticosterone; Gastric Mucosa; Glucocorticoid | 2003 |
Estradiol treatment ameliorates acetic acid-induced gastric and colonic injuries in rats.
Topics: Acetic Acid; Animals; Colitis; Dose-Response Relationship, Drug; Epithelium; Estradiol; Female; Male | 2003 |
Synthesis, characterization and antiinflammatory-analgesic properties of 6-(alpha-amino-4-chlorobenzyl)thiazolo [3,2-b]-1,2,4-triazol-5-ols.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoquinones; Capillary Per | 2004 |
The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cell Division; Centella; Chromatography, High Pressure Liqu | 2004 |
Role of brain-gut axis in healing of gastric ulcers.
Topics: Acetic Acid; Animals; Brain; Capsaicin; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Gastri | 2004 |
Mucosal irritative and healing impairment action of risedronate in rat stomachs: comparison with alendronate.
Topics: Acetic Acid; Alendronate; Animals; Diphosphonates; Etidronic Acid; Gastric Mucosa; Male; Rats; Rats, | 2004 |
Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Aspirin; Azadirachta; Bacopa; Cold Temperature; Diabetes Me | 2004 |
Antiulcer activity of Utleria salicifolia rhizome extract.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Dose-Response | 2004 |
Serum response factor is a critical requirement for VEGF signaling in endothelial cells and VEGF-induced angiogenesis.
Topics: Acetic Acid; Actins; Animals; Cell Division; Cell Movement; Cells, Cultured; Collagen; Culture Media | 2004 |
Evaluation of Pongamia pinnata root extract on gastric ulcers and mucosal offensive and defensive factors in rats.
Topics: Acetic Acid; Animals; Anti-Infective Agents, Local; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ul | 2003 |
[Effect of Chinese drugs for jianpi huayu on healing quality of gastric ulcer in rats].
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Drugs, Chinese Herbal; Epidermal Growth Factor; ErbB Recept | 2004 |
Experimentally induced ulcers and gastric sensory-motor function in rats.
Topics: Acetic Acid; Animals; Gastrointestinal Motility; Male; Muscle Contraction; Muscle, Smooth; Pain; Phy | 2005 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
[Protective effect of the intraperitoneal and intragastric administration of PGP-peptide on ethanol-induced erosions and acetate-induced ulcers in rats].
Topics: Acetic Acid; Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug | 2004 |
Synthesis, biological evaluation and kinetic studies of glyceride prodrugs of diclofenac.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Chromatography, High Pressu | 2004 |
COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions.
Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxyge | 2005 |
A new property of endogenous immunostimulator Taftsin.
Topics: Acetic Acid; Adjuvants, Immunologic; Animals; Ethanol; Male; Rats; Restraint, Physical; Stomach Ulce | 2004 |
Ganoderma lucidum polysaccharide fractions accelerate healing of acetic acid-induced ulcers in rats.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Disease Models, Animal; Dose-Response | 2004 |
Gastric ulcers evoke hyperexcitability and enhance P2X receptor function in rat gastric sensory neurons.
Topics: Acetic Acid; Adenosine Triphosphate; Animals; Carbocyanines; Cells, Cultured; Dose-Response Relation | 2005 |
Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes.
Topics: Acetic Acid; Animals; Colitis; Darkness; Ethanol; Female; Gastric Mucosa; Inflammation; Intestinal M | 2005 |
Is gastric ulceration different in normal and malnourished rats?
Topics: Acetic Acid; Animals; Body Weight; Corticosterone; Cytoprotection; Dinoprostone; Ethanol; Female; Ga | 2005 |
Administration of L-arginine reduces the delay of the healing process caused by ibuprofen. Implication of COX and growth factors expression.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Chronic Disease; Cyclooxyge | 2005 |
Therapeutic effect of D-002 (abexol) on gastric ulcer induced experimentally in rats.
Topics: Acetic Acid; Acute Disease; Administration, Oral; Animals; Anti-Ulcer Agents; Antioxidants; Chronic | 2005 |
Anti-inflammatory, antinociceptive, and gastric effects of Hypericum perforatum in rats.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; | 2005 |
Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Free Radicals; Gastric Mucosa; Glutathione Peroxid | 2005 |
[Expression and activity of cyclooxygenases-1 and -2 in acetic acid induced gastric ulcer in rats].
Topics: Acetic Acid; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Isoenzymes; Male; Rats; Rats, Sprague-Dawl | 2001 |
Cell proliferation in the gastric epithelium of the ulcer rat.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Epithelial Cells; | 2005 |
Gastroprotective and ulcer healing effect of ferruginol in mice and rats: assessment of its mechanism of action using in vitro models.
Topics: Abietanes; Acetic Acid; Animals; Anti-Ulcer Agents; Biphenyl Compounds; Cell Line; Cell Survival; Di | 2006 |
Gaultherin, a natural salicylate derivative from Gaultheria yunnanensis: towards a better non-steroidal anti-inflammatory drug.
Topics: Abdominal Pain; Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 2006 |
Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Acetic Acid; Animals; Chlorpheniramine; Chronic Disease; Drug Synergis | 2005 |
[Study of the effect of exceed critical extracts from Radix Aucklandiae on experimental gastric ulcer model].
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Disease Models, Animal; Drugs, Chinese Herbal; Gastric Muco | 2005 |
Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats.
Topics: Acetic Acid; Adrenal Glands; Animals; Anti-Inflammatory Agents, Non-Steroidal; Consciousness; Cortic | 2006 |
Differential effects of selective and non-selective inhibition of nitric oxide synthase on the expression and activity of cyclooxygenase-2 during gastric ulcer healing.
Topics: Acetic Acid; Amidines; Animals; Benzylamines; Blotting, Western; Cyclooxygenase 2; Enzyme Inhibitors | 2006 |
The cationic host defense peptide rCRAMP promotes gastric ulcer healing in rats.
Topics: Acetic Acid; Actins; Animals; Anti-Ulcer Agents; Antimicrobial Cationic Peptides; Blotting, Western; | 2006 |
Analgesic, antiinflammatory, and ulcerogenic studies of meloxicam solid dispersion prepared with polyethylene glycol 6000.
Topics: Abdominal Pain; Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 2006 |
Evaluation of anti-inflammatory and analgesic activity of a new class of biphenyl analogs in animal models of inflammation.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; C-Rea | 2006 |
Anti-ulcer effect of tea catechin in rats.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Camellia sinensis; Catechin; Dose-Res | 2006 |
[Effects of jianwei yuyang granule on inflammatory reaction and NF-kappaB expression in rat gastric mucosa of ulcer healing and recurrence].
Topics: Acetic Acid; Animals; Drug Combinations; Drugs, Chinese Herbal; Female; Gastric Mucosa; Male; NF-kap | 2006 |
Luminal stimuli acutely sensitize visceromotor responses to distension of the rat stomach.
Topics: Acetic Acid; Afferent Pathways; Animals; Catheterization; Disease Models, Animal; Dyspepsia; Electro | 2007 |
[Effect of mucosal protective on the quality of gastric ulcer healing].
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Diterpenes; Drug Therapy, Combination; ErbB Receptors; Gast | 2007 |
Synthesis of 3-[4'-(p-chlorophenyl)-thiazol-2'-yl]-2-[(substituted azetidinone/thiazolidinone)-aminomethyl]-6-bromoquinazolin-4-ones as anti-inflammatory agent.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azetidines; Dose-Response Relationshi | 2007 |
2-Amino/azido/hydrazino-5-alkoxy-5H-[1]benzopyrano[4,3-d]pyrimidines: synthesis and pharmacological evaluation.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Carragee | 2007 |
Gastroprotective effects of DA-6034, a new flavonoid derivative, in various gastric mucosal damage models.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Centra | 2007 |
Impairment of gastric ulcer healing by alendronate, a nitrogen-containing bisphosphonate, in rats.
Topics: Acetic Acid; Alendronate; Animals; Bone Density Conservation Agents; Cells, Cultured; Cyclooxygenase | 2007 |
Effect of peroxisome proliferator-activated receptor-alpha agonist (bezafibrate) on gastric secretion and gastric cytoprotection in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Bezafibrate; Ethanol; Gastric Acid; Gastric Mucosa; Indomet | 2007 |
Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Base Sequence; Cyclooxygenas | 2007 |
Antinociceptive and anti-inflammatory steroidal saponins from Dracaena ombet.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Dose- | 2007 |
Hydrogen sulfide enhances ulcer healing in rats.
Topics: Acetic Acid; Animals; Hydrogen Sulfide; Intubation, Gastrointestinal; Male; Organothiophosphorus Com | 2007 |
[Somatic pain sensitivity of conscious rats with chronic gastric ulcers].
Topics: Acetic Acid; Animals; Male; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Stomach Ul | 2007 |
Flavonoid-rich fraction of Maytenus ilicifolia Mart. ex. Reiss protects the gastric mucosa of rodents through inhibition of both H+,K+ -ATPase activity and formation of nitric oxide.
Topics: Acetic Acid; Animals; Female; Flavonoids; Gastric Acid; Gastric Juice; Gastric Mucosa; Glutathione; | 2007 |
Prophylactic effect of rebamipide against the irritative and healing impairment actions of alendronate in rat stomachs.
Topics: Acetic Acid; Administration, Oral; Alanine; Alendronate; Animals; Anti-Ulcer Agents; Blotting, Weste | 2007 |
Effect of dopamine on the healing of acetic acid-induced gastric ulcers in rats.
Topics: Acetic Acid; Animals; Dopamine; Gastric Mucosa; Gene Expression; Male; Rats; Rats, Sprague-Dawley; R | 2007 |
Selank and its metabolites maintain homeostasis in the gastric mucosa.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Ethanol; Gastric Mucosa; Homeostasis; Male; Oligopeptides; | 2007 |
Studies of gastric mucosa regeneration and safety promoted by Mouriri pusa treatment in acetic acid ulcer model.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Cell Proliferation; Gastric Mucosa; M | 2008 |
Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis.
Topics: Acetic Acid; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Ethanol; G | 2008 |
New celecoxib derivatives as anti-inflammatory agents.
Topics: Acetic Acid; Animals; Carrageenan; Celecoxib; Chronic Disease; Crystallization; Cyclooxygenase 1; Cy | 2008 |
Synthesis and biological evaluation of thieno[2,3-d]pyrimidine derivatives for anti-inflammatory, analgesic and ulcerogenic activity.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Disease Models, An | 2007 |
Ketorolac-dextran conjugates: synthesis, in vitro and in vivo evaluation.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Buffers; Carrag | 2007 |
Cultured bone marrow cell local implantation accelerates healing of ulcers in mice.
Topics: Acetic Acid; Animals; Bone Marrow Transplantation; Cell Transdifferentiation; Cells, Cultured; Femal | 2008 |
Histomorphological characteristics of accelerated healing of acetate ulcers under the effect of glyprolines.
Topics: Acetic Acid; Animals; Gastric Mucosa; Male; Oligopeptides; Proline; Rats; Regeneration; Stomach Ulce | 2007 |
Synthesis and pharmacological evaluation of 2-substituted benzo[b]thiophenes as anti-inflammatory and analgesic agents.
Topics: Acetic Acid; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; C | 2009 |
Effect of 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy) chalcone (sofalcone) on chronic gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cell Division; Chalcone; Chalcones; Gastric Mucos | 1984 |
Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Female; Gastric Acid; Gastric Mucosa; | 1984 |
[Experimental studies on gastric ulcer (6). Endoscopical evaluation of healing processes of acetic acid ulcer in rats (2): Healing, recurrence and relapse of ulcer].
Topics: Acetates; Acetic Acid; Age Factors; Animals; Female; Gastric Mucosa; Gastroscopy; Male; Rats; Recurr | 1984 |
Changes in synthetic activity of sulfated mucosubstances in healing process of acetic acid ulcer in rats and effect of anti-ulcer agents.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Gastric Mucosa; Male; Rats; Rats, Inbred Strains; | 1984 |
Experimental studies on gastric ulcer. (4). Sequential observation and evaluation of gastric ulcers by endoscope in the rat.
Topics: Acetates; Acetic Acid; Animals; Gastroscopy; Rats; Rats, Inbred Strains; Stomach Ulcer | 1983 |
Exacerbation of acetic acid ulcer induced by non-steroidal anti-inflammatory drugs in rats.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents; Aspirin; Gastric Emptying; Gastric Juice; | 1983 |
[Studies on defensive factors of experimental ulcers (2). Increasing action of aceglutamide aluminum on defensive factors in acetic acid ulcers of rats (author's transl)].
Topics: Acetates; Acetic Acid; Administration, Oral; Aluminum; Animals; Anti-Ulcer Agents; Gastric Mucosa; G | 1982 |
[Experimental study for the gastric mucosal damage--especially, the effect of cigarette smoking on the healing course of acetic acid ulcer in rats (author's transl)].
Topics: Acetates; Acetic Acid; Animals; Male; Nicotine; Rats; Rats, Inbred Strains; Smoking; Stomach Ulcer; | 1981 |
Effect of basic fibroblast growth factor on microvascular regeneration from gastric ulcerative lesion-increased binding site of bFGF after CS23 treatment.
Topics: Acetates; Acetic Acid; Animals; Binding Sites; Fibroblast Growth Factor 2; Granulation Tissue; Micro | 1995 |
Changes in gastric function and healing of chronic gastric ulcers in aged rats.
Topics: Acetates; Acetic Acid; Aging; Animals; Cell Division; Gastric Acid; Gastrins; Gastrointestinal Motil | 1995 |
Influence of ammonia solution on gastric mucosa and acetic acid induced ulcer in rats.
Topics: Acetates; Acetic Acid; Ammonia; Animals; Bromodeoxyuridine; Cell Division; DNA; Dose-Response Relati | 1994 |
Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats.
Topics: Acetates; Acetic Acid; Allopurinol; Animals; Cyclooxygenase Inhibitors; Dimethyl Sulfoxide; Free Rad | 1995 |
Gene expression of keratinocyte and hepatocyte growth factors during the healing of rat gastric mucosal lesions.
Topics: Acetates; Acetic Acid; Animals; Base Sequence; Cell Line; Cells, Cultured; DNA; Fibroblast Growth Fa | 1995 |
Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine.
Topics: Acetates; Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Cimetidine; Drug Therapy, Combination; M | 1995 |
Plasticity of myofibroblasts appearing in granulation tissues after acetic acid treatment. Effect of bFGF.
Topics: Acetates; Acetic Acid; Animals; Autoradiography; Desmin; Fibroblast Growth Factor 2; Fibroblasts; Ga | 1995 |
Misoprostol reverses the inhibition of gastric hyperemia and aggravation of gastric damage by tobacco cigarette smoke in the rat.
Topics: Acetates; Acetic Acid; Analysis of Variance; Animals; Gastric Mucosa; Hyperemia; Male; Misoprostol; | 1995 |
Antiulcer action and toxicity of Styrax camporum and Caesalpinia ferrea.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Female; Gastric Acid; Gastric Mucosa; Plant Extra | 1995 |
Enhancement in gastric mucosal EGF and PDGF receptor expression with ulcer healing by sulglycotide.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cell Membrane; Chronic Disease; ErbB Receptors; G | 1995 |
Wound healing of acetic acid-induced gastric ulcer in rats and the effects of cimetidine and calcitonin, with special reference to prolylhydroxylase and collagenase enzyme activity.
Topics: Acetates; Acetic Acid; Animals; Calcitonin; Cells, Cultured; Cimetidine; Collagenases; Gastric Mucos | 1995 |
Inhibition of nitric oxide synthase delays healing of chronic gastric ulcers.
Topics: Acetates; Acetic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Gastric Mucosa; Male; Nitric O | 1993 |
Two phenotypically distinct B lymphocytes (IgMhighIgDlow and IgMlowIgDhigh) in chronic gastric ulcer in the rat.
Topics: Acetates; Acetic Acid; Animals; B-Lymphocyte Subsets; Chronic Disease; Fluorescent Antibody Techniqu | 1995 |
[Therapeutic effect of IGN-2098, a new antiulcer drug (H2-antagonist), in the ulcer diminishing period against acetic acid-induced gastric ulcer in rats].
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Famotidine; Histamine H2 Antagonists; Male; Piper | 1995 |
Acceleration of healing of gastric ulcers induced in rats by liquid diet: importance of tissue contraction.
Topics: Acetates; Acetic Acid; Animal Feed; Animals; Body Weight; Cell Division; Cellulose; Food, Formulated | 1994 |
Anti-inflammatory effects of etodolac: comparison with other non-steroidal anti-inflammatory drugs.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Ca | 1994 |
Zinc deficiency delays gastric ulcer healing in rats.
Topics: Acetates; Acetic Acid; Animals; Bromodeoxyuridine; Cell Division; Diet; Disease Models, Animal; Gast | 1995 |
Tobacco cigarette smoke aggravates gastric ulcer in rats by attenuation of ulcer margin hyperemia.
Topics: Acetates; Acetic Acid; Animals; Hyperemia; Injections, Subcutaneous; Male; Nicotiana; Nicotine; Plan | 1995 |
Effect of cimetidine and omeprazole on gastric ulcer healing of rats with limited food intake time.
Topics: Acetates; Acetic Acid; Administration, Oral; Analysis of Variance; Animals; Atropine; Cimetidine; Di | 1994 |
Validity of kissing gastric ulcers induced in rats for screening of antiulcer drugs.
Topics: Acetates; Acetic Acid; Aluminum Hydroxide; Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; D | 1994 |
Cell proliferation kinetics in acetic acid-induced gastric ulcer evaluated by immunohistochemical staining of proliferating cell nuclear antigen.
Topics: Acetates; Acetic Acid; Animals; Cell Division; Gastric Mucosa; Immunoenzyme Techniques; Male; Nuclea | 1993 |
Influence of capsaicin-sensitive afferent fibers on acetic acid-induced chronic gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Chronic Disease; Male; N | 1994 |
Persistent lack of somatostatin receptors in gastric mucosa of healing ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Autoradiography; Cicatrix; ErbB Receptors; Female; Gastric Mucosa; R | 1994 |
Effects of misoprostol on delayed ulcer healing induced by aspirin.
Topics: Acetates; Acetic Acid; Animals; Aspirin; Gastric Mucosa; Male; Misoprostol; Rats; Rats, Inbred Strai | 1994 |
3,3'-Bi-[1,3-thiazolidine-4-one] system. VII. Synthesis and SARS of some 2-heteroaryl derivatives with antiinflammatory and related activities.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Ca | 1994 |
Biochemical and pharmacological properties of a newly synthesized proton pump (H+/K(+)-ATPase) inhibitor, TY-11345 in experimental animals.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Benzimidazoles; Duodenal Ulcer; Epirizole; Ethano | 1993 |
Protective action of vinpocetine against experimentally induced gastric damage in rats.
Topics: Acetates; Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Dinoprostone; Ethanol; Fema | 1993 |
Enhancement in gastric mucosal laminin receptor expression with ulcer healing.
Topics: Acetates; Acetic Acid; Animals; Gastric Mucosa; Laminin; Male; Radioligand Assay; Rats; Rats, Spragu | 1993 |
Apoptosis: genetically programmed physiologic cell loss in normal gastric oxyntic mucosa and in mucosa of grossly healed gastric ulcer.
Topics: Acetates; Acetic Acid; Animals; Apoptosis; Epithelium; Gastric Mucosa; Male; Microscopy, Electron; O | 1993 |
[The pharmacodynamics of troxipide on experimental gastric ulcers in rats].
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Female; Male; Piperidines; Rats; Rats | 1993 |
Evaluation of acetic acid-induced gastric ulcers in dogs by endoscopic ultrasonography.
Topics: Acetates; Acetic Acid; Animals; Dogs; Gastroscopy; Predictive Value of Tests; Sensitivity and Specif | 1993 |
[Anti-ulcer effect of the drug OF-743 in an acid model of ulcer formation by the Okabe method].
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Disease Models, Animal; Gastric Mucosa; Male; Pep | 1993 |
Effect of NC-1300-O-3 on healing of acetic acid-induced gastric ulcers in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Benzimid | 1993 |
Fibroblast growth factor in gastroprotection and ulcer healing: interaction with sucralfate.
Topics: Acetates; Acetic Acid; Acute Disease; Animals; Aspirin; Disease Models, Animal; Dose-Response Relati | 1993 |
Effect and mechanism of sucralfate on healing of acetic acid-induced gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Dinoprostone; Gastric Mucosa; Indomethacin; Male; Rats; Rats, Inbred | 1993 |
Mechanism by which indomethacin delays gastric ulcer healing in the rat: inhibited contraction of the ulcer base.
Topics: Acetates; Acetic Acid; Animals; Connective Tissue; Gastric Mucosa; Indomethacin; Male; Muscle Contra | 1993 |
Effects of indomethacin and prednisolone on the different stages of healing of acetic acid-induced gastric ulcers in the rat.
Topics: Acetates; Acetic Acid; Animals; Collagen; Connective Tissue; Gastric Mucosa; Indomethacin; Male; Pre | 1993 |
Increase in mucosal and connective tissue-type mast cells in the stomach with acetic acid-induced ulcer in rat.
Topics: Acetates; Acetic Acid; Animals; Cell Count; Connective Tissue; Gastric Mucosa; Male; Mast Cells; Rat | 1996 |
Anti-inflammatory and analgesic activity of Baccharis trimera: identification of its active constituents.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanols; Carra | 1996 |
[A study on factors of acupuncture methods affecting effects through acupuncture treatments for experimental gastric ulcer in rats].
Topics: Acetates; Acetic Acid; Acupuncture Therapy; Animals; Electroacupuncture; Female; Lipid Peroxides; Ma | 1995 |
[Influence of KU-1257 on the recurrence and relapse of acetic acid-induced chronic gastric ulcers in rats].
Topics: Acetates; Acetic Acid; Animals; Chronic Disease; Cimetidine; Histamine H2 Antagonists; Male; Phenylu | 1996 |
Role of polymorphonuclear leukocytes and oxygen-derived free radicals in chronic gastric lesion induced by acetic acid in rat.
Topics: Acetic Acid; Allopurinol; Animals; Antimetabolites; Capillary Permeability; Enzyme Inhibitors; Epith | 1996 |
Influence of age on natural and delayed healing of experimentally-induced gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Indomethacin; Male; | 1996 |
Simultaneous evaluation of gastric and duodenal ulcers-healing activities of anti-ulcer agents in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Atropine; Chronic Disease; Cimetidine; Duodenal Ulcer; Hist | 1996 |
Synchronized induction in bFGF and Cdk2 during gastric ulcer healing.
Topics: Acetic Acid; Animals; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Fibro | 1996 |
Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Capsaicin; Chronic Disease; Cimetidine; Drug Therapy, Combi | 1996 |
Helicobacter pylori infection delays the healing of acetic acid-induced gastric ulcer in Japanese monkeys.
Topics: Acetic Acid; Animals; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Macaca; Stomach | 1996 |
Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice.
Topics: Acetic Acid; Acids; Animals; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 | 1997 |
Simultaneous restitution of matrix and cells in gastric ulcer: use of a combined in-situ hybridization and immunohistochemistry technique applicable to paraffin-embedded tissue.
Topics: Acetic Acid; Animals; Collagen; Digoxigenin; Extracellular Matrix; Immunohistochemistry; In Situ Hyb | 1997 |
Role of neutrophils in a rat model of gastric ulcer recurrence caused by interleukin-1 beta.
Topics: Acetic Acid; Animals; Antibodies, Monoclonal; Cell Count; Endoscopy; Gastric Mucosa; Humans; Injecti | 1997 |
Investigations on the protective action of Condonopsis pilosula (Dangshen) extract on experimentally-induced gastric ulcer in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Drugs, Chinese Herbal; Duodenum; Gastric Acid; Gastric Muco | 1997 |
Increased expression of transforming growth factor-beta1 during gastric ulcer healing in rats.
Topics: Acetic Acid; Alprostadil; Animals; Blotting, Northern; Extracellular Matrix Proteins; Gastric Mucosa | 1997 |
Prevention of gastric ulcer relapse induced by indomethacin in rats by a mutein of basic fibroblast growth factor.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agen | 1997 |
Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats.
Topics: Acetic Acid; Animals; Collagenases; Connective Tissue; Disease Models, Animal; Gastric Mucosa; Gelat | 1997 |
Inoculation of VacA- and CagA- Helicobacter pylori delays gastric ulcer healing in the rat.
Topics: Acetic Acid; Animals; Antigens, Bacterial; Apoptosis; Bacterial Proteins; Cell Division; Disease Mod | 1997 |
ME-3407, a new antiulcer agent, inhibits acid secretion by interfering with redistribution of H(+)-K(+)-ATPase.
Topics: Acetic Acid; Androstadienes; Animals; Anti-Ulcer Agents; Cyclic AMP-Dependent Protein Kinases; Enzym | 1997 |
Pharmacological profile of the novel potent antirheumatic 4-(2',4'-difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic acid.
Topics: Abdominal Pain; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Art | 1997 |
Changes in sulfated macromolecules produced in vivo during normal and indomethacin-delayed ulcer healing in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Gastric Mucosa; Glycosaminoglycans; G | 1997 |
Pepsinogen C gene product is a possible growth factor during gastric mucosal healing.
Topics: Acetic Acid; Animals; DNA, Complementary; Gastric Mucosa; Gastritis; Gene Expression Regulation; Gro | 1997 |
Gastric ulcer healing in the rat: kinetics and localisation of de novo procollagen synthesis.
Topics: Acetic Acid; Animals; Extracellular Matrix; Gastric Mucosa; Gene Expression; Immunohistochemistry; I | 1997 |
The potentiating actions of cigarette smoking on ethanol-induced gastric mucosal damage in rats.
Topics: Acetic Acid; Animals; Cold Temperature; Dinoprostone; Ethanol; Gastric Mucosa; Leukotriene C4; Male; | 1997 |
Kinetics of fibroblasts in ulcer healing in rats: interference with indomethacin.
Topics: Acetic Acid; Actins; Animals; Apoptosis; Culture Techniques; Cyclooxygenase Inhibitors; Disease Mode | 1997 |
Kinetics and collagenolytic role of eosinophils in chronic gastric ulcer in the rat.
Topics: Acetic Acid; Animals; Antibodies, Monoclonal; Antibody Specificity; Chronic Disease; Collagenases; E | 1997 |
Relationship between healing of acetic acid-induced chronic gastric ulcer and connexin.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Chronic Disease; Cimetidine; Connexins; Epidermal Growth Fa | 1997 |
Basic fibroblast growth factor increases constitutive nitric oxide synthase during healing of rat gastric ulcers.
Topics: Acetic Acid; Animals; Enzyme Inhibitors; Fibroblast Growth Factor 2; Gastric Mucosa; Humans; Male; N | 1997 |
Mechanistic study of adverse actions of cigarette smoke exposure on acetic acid-induced gastric ulceration in rats.
Topics: Acetic Acid; Allopurinol; Animals; Dinoprostone; Enzyme Activation; Gastric Mucosa; Male; Nicotiana; | 1998 |
Phosphatidylcholine-associated aspirin accelerates healing of gastric ulcers in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Combinations; Male; Pho | 1998 |
[Effect of lafutidine, a novel antiulcer agent, on healing and relapse of acetic acid-induced gastric ulcer in rats].
Topics: Acetamides; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Dose-Response Relationship, Drug; F | 1998 |
Mechanism by which indomethacin delays the healing of acetic acid-induced ulcers in rats. Role of neutrophil antichemotactic and chemotactic activities.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemotactic Factors; Dinoprostone; Ga | 1998 |
Bacteria rapidly colonize and modulate healing of gastric ulcers in rats.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Bacitracin; Escherichia coli; Gastric Acid; Lactobacill | 1998 |
Anti-ulcer effects of antioxidants: effect of probucol.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Antioxidants; Chronic Disease; Cimetidine; D | 1998 |
Effects of novel anti-inflammatory compounds on healing of acetic acid-induced gastric ulcer in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; C | 1998 |
Localization of cyclooxygenase-2 and regulation of its mRNA expression in gastric ulcers in rats.
Topics: Acetic Acid; Animals; Antibodies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhi | 1998 |
Anti-ulcer effects of antioxidants, quercetin, alpha-tocopherol, nifedipine and tetracycline in rats.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Antioxidants; Calcium Channel Blocke | 1998 |
Relationship between vascular endothelial growth factor and angiogenesis in spontaneous and indomethacin-delayed healing of acetic acid-induced gastric ulcers in rats.
Topics: Acetic Acid; Animals; Cyclooxygenase Inhibitors; Endothelial Growth Factors; Gastric Mucosa; Indomet | 1998 |
Midkine gene expression in the healing process of gastric ulcer.
Topics: Acetic Acid; Animals; Carrier Proteins; Cell Division; Cell Line; Cytokines; Fibroblasts; Gastric Mu | 1999 |
Healing effects of heparin on acetic acid-induced gastric ulcers in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Dinoprostone; Dose-Response Relationship, Drug; Gastric Muc | 1998 |
Local downregulation of enterochromaffin-like cell histamine formation in ulcer healing: a study in rats.
Topics: Acetic Acid; Animals; Chromogranin A; Chromogranins; Down-Regulation; Enterochromaffin-like Cells; F | 1999 |
A new ulcer model, "unhealed gastric ulcers", induced by chronic treatment with indomethacin in rats with acetic acid ulcers.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cyclooxygenase Inh | 1999 |
Delayed healing of acetic-acid-induced gastric ulcer in portal hypertensive rats.
Topics: Acetic Acid; Animals; Cell Division; Disease Models, Animal; Gastric Mucosa; Hypertension, Portal; L | 1999 |
Regulation by endogenous interleukin-1 of mRNA expression of healing-related factors in gastric ulcers in rats.
Topics: Acetic Acid; Animals; Cells, Cultured; Chemotaxis; Dinoprostone; Dose-Response Relationship, Drug; G | 1999 |
Gastrointestinal absorption of a new reversible proton pump inhibitor, YJA-20379-8, and its pharmacokinetics after oral administration in acetic acid-induced gastric ulcer in rats.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Area Under Curve; Chromatography, Hig | 1999 |
Distribution of Helicobacter pylori in a Mongolian gerbil gastric ulcer model.
Topics: Acetic Acid; Animals; Colony Count, Microbial; Disease Models, Animal; Gastric Mucosa; Gerbillinae; | 1999 |
Effect of recombinant human basic fibroblast growth factor on stomach ulcers in rats and mice.
Topics: Acetic Acid; Animals; DNA; Female; Fibroblast Growth Factor 2; Gastric Mucosa; Ligation; Male; Mice; | 1999 |
Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing.
Topics: Acetic Acid; Analysis of Variance; Animals; Hematologic Agents; Immunoenzyme Techniques; Male; Neutr | 2000 |
Autonomic nervous regeneration in acetic acid-induced ulcer from the viewpoint of synapse formation--effect of basic fibroblast growth factor and sofalcone in the rat.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Autonomic Nervous System; Autoradiography; Binding Sites; C | 2000 |
The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats.
Topics: Acetic Acid; Animals; Antigens, Bacterial; Apoptosis; Bacterial Proteins; Blotting, Western; Cell Di | 2000 |
Synthesis and pharmacological screening of 1,3,4-thiadiazino[2,3-b]quinazoline derivatives.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, A | 2000 |
Effect of oligofucose derivatives on acetic acid-induced gastric ulcer in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Male; | 2001 |
Expression of a specific mucin type recognized by monoclonal antibodies in the rat gastric mucosa regenerating from acetic acid-induced ulcer.
Topics: Acetic Acid; Animals; Antibodies, Monoclonal; Disease Models, Animal; Gastric Mucins; Gastric Mucosa | 2001 |
Expression of decorin and biglycan in rat gastric tissue: effects of ulceration and basic fibroblast growth factor.
Topics: Acetic Acid; Animals; Apoptosis; Biglycan; Decorin; Disease Models, Animal; Drug Evaluation, Preclin | 2001 |
Effect of centrally administered prolactin on gastric and duodenal ulcers in rats.
Topics: Acetic Acid; Animals; Chronic Disease; Cysteamine; Duodenal Ulcer; Ethanol; Gastric Acid; Gastric Ac | 2001 |
The antiulcerative effect of Thai Musa species in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Female; Indomethacin; Pla | 2001 |
Macrophage migration inhibitory factor is an important mediator in the pathogenesis of gastric inflammation in rats.
Topics: Acetic Acid; Acute Disease; Animals; Antibodies, Monoclonal; Disease Models, Animal; Gastritis; Gene | 2001 |
Effect of jianpiyiqi prescription on the expression of heat shock proteins in acetic acid-induced chronic gastric ulcer rats.
Topics: Acetic Acid; Animals; Chronic Disease; Drugs, Chinese Herbal; Heat-Shock Proteins; Male; Phytotherap | 2001 |
Effect of hyperprolactinaemia as induced by pituitary homografts under kidney capsule on gastric and duodenal ulcers in rats.
Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Cysteamine; Duodenal Ulcer; Gastric Acid; Hype | 2001 |
Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Chronic Disease; Cysteamine; Disease Models, | 2001 |
Prophylactic and curative effects of Bacopa monniera in gastric ulcer models.
Topics: Acetic Acid; Animals; Antioxidants; Aspirin; Catalase; Cell Division; Cold Temperature; Disease Mode | 2001 |
Experimental ulcers alter voltage-sensitive sodium currents in rat gastric sensory neurons.
Topics: Acetic Acid; Anesthetics, Local; Animals; Disease Models, Animal; Ganglia, Spinal; Gastritis; Hypera | 2002 |
Effect of butanol fraction of Panax ginseng head on gastric lesion and ulcer.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Butanols; Gast | 2002 |
[Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats].
Topics: Acetic Acid; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dino | 2001 |
Transient increase of rat gastric amylin in the neonatal period and in experimental ulcers.
Topics: Acetic Acid; Amyloid; Animals; Animals, Newborn; Gastric Mucosa; Indicators and Reagents; Islet Amyl | 2002 |
Time-course changes of ECL cell markers in acetic acid-induced gastric ulcers in rats.
Topics: Acetic Acid; Animals; Biomarkers; Blotting, Northern; Down-Regulation; Enterochromaffin-like Cells; | 2002 |
Influence of Helicobacter pylori infection on healing and relapse of acetic acid ulcers in Mongolian gerbils.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cyclooxygenase Inh | 2002 |
Acidic fibroblast growth factor accelerates the healing of acetic-acid-induced gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Aluminum Hydroxide; Animals; Antacids; Drug Combinations; Famotidine; Female; | 1992 |
[Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats].
Topics: Acetates; Acetic Acid; Adenosine Triphosphatases; Animals; Chronic Disease; Drug Therapy, Combinatio | 1992 |
[Therapeutic effect of moxibustion on experimental gastric ulcer of rats and its mechanism].
Topics: Acetates; Acetic Acid; Animals; Dinoprost; Dinoprostone; Female; Gastric Mucosa; Male; Moxibustion; | 1992 |
Gastroprotective and ulcer-healing activities of a new H2-receptor antagonist: ebrotidine.
Topics: Acetates; Acetic Acid; Animals; Benzenesulfonates; Epidermal Growth Factor; Ethanol; Gastric Acid; G | 1992 |
[The antigastroulcerative activity of beta-sitosterol-beta-D-glucoside and its aglycone in rats].
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Female; Male; Rats; Rats, Inbred Strains; Sitoste | 1992 |
[The immunohistochemical study on the recurrent mechanism of acetic acid induced gastric ulcer in rats--extracellular matrix and cellular kinetics].
Topics: Acetates; Acetic Acid; Animals; Cell Cycle; Epithelium; Extracellular Matrix; Fibronectins; Gastric | 1992 |
[The gastric mucosal adhesiveness of Z-103 in rats with chronic ulcer].
Topics: Acetates; Acetic Acid; Adhesiveness; Animals; Anti-Ulcer Agents; Carnosine; Chronic Disease; Dipepti | 1992 |
Effects of H2-receptor antagonists on matrix metalloproteinases in rat gastric tissues with acetic acid-induced ulcer.
Topics: Acetates; Acetic Acid; Animals; Extracellular Matrix; Gelatin; Histamine H2 Antagonists; Male; Metal | 1991 |
Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Cimetidine; Dose-Response Relationship, Drug; Granulation Tissue; Ma | 1990 |
Helicobacter pylori affects the quality of experimental gastric ulcer healing in a new animal model.
Topics: Acetates; Acetic Acid; Animals; Disease Models, Animal; Gastric Mucosa; Helicobacter pylori; Male; R | 1991 |
Research on heterocyclic compounds. XXVIII. Imidazo[1,2-c]pyrimidines.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bridged Bicyclo Compounds; | 1991 |
Evaluation of acetic acid-induced gastric ulcers in rats by scanning acoustic microscopy.
Topics: Acetates; Acetic Acid; Acoustics; Animals; Disease Models, Animal; Male; Microscopy; Rats; Rats, Inb | 1991 |
Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidi | 1991 |
Effects of the new anti-ulcer agent 12-sulfodehydroabietic acid monosodium salt on healing of acetic acid-induced gastric ulcers in rats.
Topics: Abietanes; Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Carbenoxolone; Diterpenes; Gastric Muc | 1991 |
Effects of prostaglandins on hydrocortisone-induced delayed healing of chronic gastric ulcers in the rat.
Topics: 16,16-Dimethylprostaglandin E2; Acetates; Acetic Acid; Animals; Epoprostenol; Gastric Mucosa; Hydroc | 1991 |
Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Dinoprostone; Gastric Mucosa; Indomethacin; Male; Omeprazole; Rats; | 1991 |
Healing of acetic acid-induced gastric ulcer and gastric mucosal PGI2 level in rats.
Topics: Acetates; Acetic Acid; Animals; Epoprostenol; Gastric Mucosa; Male; Rats; Rats, Inbred Strains; Recu | 1990 |
Roles of muscularis mucosae and myofibroblasts in the healing process of acetic acid-induced ulcer.
Topics: Acetates; Acetic Acid; Animals; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Gastri | 1990 |
"Healed" experimental gastric ulcers remain histologically and ultrastructurally abnormal.
Topics: Acetates; Acetic Acid; Animals; Gastric Mucosa; Male; Microscopy, Electron; Rats; Rats, Inbred Strai | 1990 |
Vascular and microvascular changes--key factors in the development of acetic acid-induced gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Gastric Mucosa; Granulation Tissue; Male; Microcirculation; Microsco | 1990 |
Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat.
Topics: Acetates; Acetic Acid; Animals; Drug Therapy, Combination; Epidermal Growth Factor; Male; Omeprazole | 1990 |
Effect of omeprazole on delayed healing of acetic acid-induced gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Drug Therapy, Combination; Gastric Acid; Histamine; Indomethacin; Ma | 1990 |
Efficacy of combined ranitidine and pentacaine treatment in experimentally induced gastric damage in rats.
Topics: Acetates; Acetic Acid; Anesthetics, Local; Animals; Carbamates; Drug Therapy, Combination; Female; P | 1990 |
Effect of zinc acexamate and ranitidine on chronic gastric lesions in the rat.
Topics: Acetates; Acetic Acid; Aminocaproates; Aminocaproic Acid; Animals; Anti-Ulcer Agents; Male; Ranitidi | 1990 |
Effects of prednisolone and human epidermal growth factor on angiogenesis in granulation tissue of gastric ulcer induced by acetic acid.
Topics: Acetates; Acetic Acid; Animals; Drug Combinations; Epidermal Growth Factor; Granulation Tissue; Male | 1989 |
Physiological significance of mucous neck cell-type mucins in the healing of acetic acid-induced gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Gastric Mucosa; Male; Mucins; Rats; Rats, Inbred Strains; Staining a | 1989 |
Nociceptive sensitivity/behavioral reactivity regulation in rats during aversive states of different nature: its mediation by opioid peptides.
Topics: Acetates; Acetic Acid; Animals; Avoidance Learning; Behavior, Animal; Body Weight; Endorphins; Femal | 1989 |
Fluorescent histochemical study on the localization of myofibroblasts in the healing of acetic acid-induced gastric ulcers in the rat.
Topics: Acetates; Acetic Acid; Animals; Fibroblasts; Fluorescein-5-isothiocyanate; Fluoresceins; Histocytoch | 1989 |
Prolylhydroxylase and collagenase activities in the healing of acetic acid-induced gastric ulcers in rats and the effects of cimetidine and elcatonin.
Topics: Acetates; Acetic Acid; Animals; Calcitonin; Cimetidine; Hydrogen-Ion Concentration; Male; Microbial | 1989 |
Roles of endogenous leukotrienes and prostaglandins in the healing of gastric ulcers induced by acetic acid in rats.
Topics: Acetates; Acetic Acid; Animals; Benzoquinones; Gastric Mucosa; Leukotriene B4; Leukotrienes; Lipoxyg | 1989 |
Characterization of metalloproteinases in rat gastric tissues with acetic acid-induced ulcers.
Topics: Acetates; Acetic Acid; Animals; Enzyme Precursors; Famotidine; Gastric Mucosa; Gelatin; Male; Metall | 1989 |
Influence of food-intake during a fixed period on hydrocortisone-induced relapse of acetic acid ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Eating; Gastric Mucosa; Hydrocortisone; Male; Rats; Rats, Inbred Str | 1989 |
Role of the mucus gel layer in the healing of acetic acid-induced gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Gels; Hydrogen-Ion Concentration; Male; Mucus; Rats; Rats, Inbred St | 1989 |
Effects of human epidermal growth factor on natural and delayed healing of acetic acid-induced gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gastric A | 1989 |
[The role of polymorphonuclear leukocytes in the mechanisms of ulcerogenesis].
Topics: Acetates; Acetic Acid; Animals; Gastric Mucosa; Histocytochemistry; Lysosomes; Male; Neutrophils; Ra | 1989 |
[Experimental chronic stomach ulcer].
Topics: Acetates; Acetic Acid; Animals; Disease Models, Animal; Gastric Mucosa; Injections; Male; Rats; Rats | 1989 |
Collagen and collagenase in ulcer tissue--1. The healing process of acetic acid ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Collagen; Gastric Mucosa; Hydroxyproline; Male; Microbial Collagenas | 1987 |
Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin.
Topics: Acetates; Acetic Acid; Animals; Dinoprostone; Gastric Acid; Gastric Mucosa; Indomethacin; Male; Rats | 1989 |
[Effect of NaHCO3 infusion on the healing of acetic acid-induced gastric ulcer in rats].
Topics: Acetates; Acetazolamide; Acetic Acid; Animals; Bicarbonates; Infusions, Parenteral; Male; Rats; Rats | 1986 |
Production of metalloproteinase in gastric tissue with acetic acid-induced ulcer or taurocholic acid-induced gastritis.
Topics: Acetates; Acetic Acid; Animals; Collagen; Endopeptidases; Gastritis; Gelatin; Male; Metalloendopepti | 1987 |
Suppression of gastric ulcer induced by stress and HCL-ethanol by intravenously administered metallothionein-II.
Topics: Acetates; Acetic Acid; Animals; Cimetidine; Ethanol; Hydrochloric Acid; Male; Metallothionein; Rats; | 1988 |
Gastroprotective and ulcer healing effects of solon, a synthetic flavonoid derivative of sophoradin.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Bicarbonates; Chalcone; Chalcones; Dinoprostone; | 1987 |
[Lysosomal enzyme activity of the gastric mucosa in rats during experimental ulcer formation].
Topics: Acetates; Acetic Acid; Animals; Disease Models, Animal; Gastric Mucosa; Histamine; Lysosomes; Rats; | 1987 |
Effects of 15(R)-15-methyl prostaglandin E2 (arbaprostil) on gastric secretion and various gastric lesions induced in rats.
Topics: Acetates; Acetic Acid; Administration, Oral; Animals; Arbaprostil; Aspirin; Dose-Response Relationsh | 1986 |
Increasing action of teprenone, a new antiulcer agent, on high-molecular-weight glycoprotein in gastric mucus during the healing process of acetic acid-induced ulcer in rats.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Diterpenes; Gastric Mucosa; Glycoprot | 1986 |
Effects of trimoprostil on healing and recurrence of acetic acid-induced gastric ulcer in rats.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Dinoprostone; Gastric Acid; Male; Pro | 1986 |
[Synthesis of 3-aromatic ring substituted 2-(4-chlorobenzoylamino)propionic acid derivatives and their antiulcer activities].
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Chlorobenzoates; Propionates; Rats; Stomach Ulcer | 1985 |
Healing-promoting action of teprenone, a new antiulcer agent on acetic acid ulcer in rats.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Diterpenes; Male; Polyenes; Proglumid | 1985 |
Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103).
Topics: Acetates; Acetic Acid; Aminopyrine; Animals; Anti-Ulcer Agents; Aspirin; Bethanechol Compounds; Cime | 1985 |
Healing-promoting action of dried aluminium hydroxide gel evaluated by the method of histological measurements in acetic acid ulcer of rats.
Topics: Acetates; Acetic Acid; Aluminum Hydroxide; Animals; Male; Propantheline; Rats; Rats, Inbred Strains; | 1985 |
[Changes in the biosynthetic activity of gastric glycoproteins during the healing process of acetic acid ulcer in rats].
Topics: Acetates; Acetic Acid; Animals; Chromatography, Gel; Gastric Mucosa; Glucosamine; Glycoproteins; Mal | 1985 |
Effect of elcatonin on experimental gastric and duodenal ulcers.
Topics: Acetates; Acetic Acid; Actihaemyl; Animals; Anti-Ulcer Agents; Aspirin; Calcitonin; Cimetidine; Cyst | 1985 |
Effects of 5-acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one, a new anti-ulcer agent, on experimental acute and chronic ulcers.
Topics: Acetates; Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Aspirin; Benzofurans; Chronic Dise | 1985 |