Page last updated: 2024-10-16

acetic acid and Gastric Ulcer

acetic acid has been researched along with Gastric Ulcer in 370 studies

Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.

Research Excerpts

ExcerptRelevanceReference
" The anthocyanidin effects were examined in gastric ulcer mouse models induced by ethanol, non-steroidal anti-inflammatory drugs (NSAIDs), ischemia-reperfusion (IR), acetic acid and duodenal ulcer induced by polypharmacy."8.02Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation. ( Dos Santos, RC; Fagundes, FL; Pereira, QC; Zarricueta, ML, 2021)
" speciosa accelerated healing of gastric ulcers even in presence of indomethacin, while decreasing bacterial loads in rats' stomachs."8.02Eremomastax speciosa (Hochst.) Cufod. counteracts the delaying effect of indomethacin on Helicobacter pylori-associated chronic gastric ulcers healing. ( Amang, AP; Choudhary, MI; Enow-Orock, GE; Maharjan, R; Mezui, C; Siwe, GT; Tan, PV; Zondegoumba, NE, 2021)
" To elucidate the mechanism responsible for delayed healing of the gastric injury in old age, we analyzed the expression of these markers in rats of different months during the healing of an acetic acid-induced gastric ulcer."7.96Immunohistochemical Studies of Age-Related Changes in Cell Proliferation and Angiogenesis during the Healing of Acetic Acid-Induced Gastric Ulcers in Rats. ( Ajayi, AF; Olaleye, SB, 2020)
" After the period of exposure, chronic gastric ulcer were induced by intraluminal application of 50% acetic acid."7.96Exposure to Mosquito Coil Smoke Delays Healing of Acetic Acid Induced Gastric Ulcer in Male Wistar Rats. ( Odukanmi, A; Olaleye, SB; Olanrewaju, TR; Salami, AT, 2020)
" This study evaluated its healing efficacy and the mechanism involved using the rat model of chronic gastric ulcer induced by serosal injection of 80% acetic acid in vivo, and human gastric adenocarcinoma cells (AGS) in vitro."7.91(-)-Myrtenol accelerates healing of acetic acid-induced gastric ulcers in rats and in human gastric adenocarcinoma cells. ( Braga, AD; Lopes, MTP; Nunes, PIG; Oliveira, FTB; Oliveira, RCM; Rao, VS; Santos, FA; Santos, VG; Silva, ACA; Sousa, DP; Viana, AFSC; Viana, DA, 2019)
"The gastroprotective property of (-)-myrtenol, a monoterpenoid, has been demonstrated previously against acute gastric ulceration induced by ethanol."7.91(-)-Myrtenol accelerates healing of acetic acid-induced gastric ulcers in rats and in human gastric adenocarcinoma cells. ( Braga, AD; Lopes, MTP; Nunes, PIG; Oliveira, FTB; Oliveira, RCM; Rao, VS; Santos, FA; Santos, VG; Silva, ACA; Sousa, DP; Viana, AFSC; Viana, DA, 2019)
"This study was conducted to investigate the effects of nitric oxide (NO) in acetic acid-induced gastric ulcer of rats and the underlying mechanisms."7.85Nitric oxide donor protects against acetic acid-induced gastric ulcer in rats via S-nitrosylation of TRPV1 on vagus nerve. ( Gong, L; Han, T; Li, J; Liu, C; Tang, Y; Xue, B; Yu, X, 2017)
"Carbon monoxide (CO), a gaseous mediator produced by haem oxygenases (HOs), has been shown to prevent stress-, ethanol-, aspirin- and alendronate-induced gastric damage; however, its role in gastric ulcer healing has not been fully elucidated."7.85Carbon monoxide released from its pharmacological donor, tricarbonyldichlororuthenium (II) dimer, accelerates the healing of pre-existing gastric ulcers. ( Brzozowski, T; Chmura, A; Ginter, G; Hubalewska-Mazgaj, M; Kwiecien, S; Magierowska, K; Magierowski, M; Pajdo, R; Sliwowski, Z, 2017)
"The purpose of our investigative work has been to determine whether there can be therapeutic roles in the administration of sildenafil citrate, heparin and several neuropeptides on an animal model where gastric ulcers were induced with acetic acid, and to compare their efficacy."7.85Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017)
"Overall the data indicate that low dose heparin, and especially sildenafil citrate and neuropeptides, can be used clinically as an alternative approach in the treatment of the gastric ulcer."7.85Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017)
"In order to elucidate the contribution of cycloxygenase (COX) enzymes in the anti-oxidant and anti-inflammatory mechanisms of nesfatin-1, which improves the healing process of chronic gastric ulcers, either acetic acid (80%; ulcer groups; n = 40) or saline (control groups; n = 40) was applied to the serosal surface of male Sprague Dawley rats' stomachs for 1 min."7.85Anti-inflammatory effects of nesfatin-1 on acetic acid-induced gastric ulcer in rats: involvement of cyclo-oxygenase pathway. ( Cantali-Ozturk, C; Demirci, EK; Kolgazi, M; Ozdemir-Kumral, ZN; Sirvanci, S; Yegen, BC; Yuksel, M, 2017)
" This study evaluated the mechanisms involved in the gastric ulcer healing of the hydroalcoholic extract from green tea (GEt), its ethyl acetate fraction, (GEAc) and epigallocatechin gallate (EGCG) using the model of acetic acid-induced gastric ulcer in rats."7.83Healing mechanisms of the hydroalcoholic extract and ethyl acetate fraction of green tea (Camellia sinensis (L.) Kuntze) on chronic gastric ulcers. ( Baggio, CH; Borato, DG; da Silva, LM; de Souza, LM; Iacomini, M; Maria-Ferreira, D; Scoparo, CT; Werner, MF, 2016)
"This research was performed to explore the protective effect of cod skin collagen peptides (CCP) on gastric ulcer induced by acetic acid."7.83Protective Effect of Cod (Gadus macrocephalus) Skin Collagen Peptides on Acetic Acid-Induced Gastric Ulcer in Rats. ( Hou, H; Li, B; Niu, H; Wang, Z; Zhang, Z, 2016)
"The model of gastric ulcer was imitated by acetic acid in rats, and AL was gavaged."7.81Comparison of the anti-ulcer activity between the crude and bran-processed Atractylodes lancea in the rat model of gastric ulcer induced by acetic acid. ( Cai, Q; Jia, TZ; Jiang, N; Ma, MY; Min, DY; Yu, Y; Yuan, Y, 2015)
"Gastric ulcers were induced by the serosal application of 100% acetic acid, and the areas of the ulcers were measured thereafter."7.79NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4(+)VEGFR1(+) cells to the ulcer granulation tissues. ( Ae, T; Amano, H; Eshima, K; Hosono, K; Ito, Y; Katada, C; Koizumi, W; Majima, M; Minamino, T; Ohno, T; Sato, T; Shibuya, M; Suzuki, T, 2013)
"The effect of fumonisin B1, an inhibitor of ceramide synthase, and of d,l,-threo-1-phenyl-2-hexadecanoylamino-3-morpholino-1-propanol (PPMP) and N-butyldeoxynojirimycin (NB-DNJ), both inhibitors of glucosylceramide synthase, on the accumulation of ceramide and formation of gastric ulcer were examined in the rat model of acetic acid-induced gastric ulcer."7.79Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. ( Hibi, T; Miura, S; Mizushima, T; Nagata, H; Nakashita, M; Suzuki, H; Taki, T; Uehara, K, 2013)
"Fumonisin B1 attenuated acetic acid-induced gastric ulcer formation, associated with a decrease in the number of apoptotic cells."7.79Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. ( Hibi, T; Miura, S; Mizushima, T; Nagata, H; Nakashita, M; Suzuki, H; Taki, T; Uehara, K, 2013)
"We evaluate the curative efficacy of the ethanolic extract (EET) of roots from Arctium lappa (bardana) in healing of chronic gastric ulcers induced by 80% acetic acid in rats and additionally studies the possible mechanisms underlying this action."7.79Ethanolic extract of roots from Arctium lappa L. accelerates the healing of acetic acid-induced gastric ulcer in rats: Involvement of the antioxidant system. ( Allemand, A; André, E; Baggio, CH; Cipriani, TR; da Silva, LM; Dartora, N; de Souza, LM; Dos Santos, AC; Marques, MC; Mendes, DA; Werner, MF, 2013)
"To observe the effects and mechanisms of Pongamia pinnata root flavonoids (PRF) on the experimental gastric ulcer induced by acetic acid and to study the mechanism of PRF on the quality of ulcer healing."7.78[Effect of Pongamia pinnata root flavonoids on the quality of ulcer healing and expression of EGF and TGF-alpha in the rat model of gastric ulcer induced by acetic acid]. ( Huang, XZ; Liu, KY; Zhu, Y, 2012)
"The models were established by acetic acid erosion, the quality of ulcer healing of PRF on the model of gastric ulcer were observed."7.78[Effect of Pongamia pinnata root flavonoids on the quality of ulcer healing and expression of EGF and TGF-alpha in the rat model of gastric ulcer induced by acetic acid]. ( Huang, XZ; Liu, KY; Zhu, Y, 2012)
" The pharmacological activity of AFE and pure scopoletin at the same equivalent dose present in AFE was investigated in rat on gastro-esophageal inflammatory models (acid reflux esophagitis, acute gastritis induced by ethanol and serotonin, and chronic gastric ulcer induced by acetic acid); gastric biochemical parameters and gastrointestinal motility."7.77Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011)
"50 g/kg) significantly prevented the formation of acid reflux esophagitis, reduced the formation of ethanol-induced acute gastric lesions, suppressed the development of gastric lesions in response to serotonin, and accelerated the healing of acetic acid-induced chronic gastric ulcer in rats with equal potency to those obtained by standard antisecretory agents (ranitidine and lansoprazole)."7.77Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011)
" (Rubiaceae) fruit, commonly known as "Noni", in an aqueous extract preparation (AFE) as used in Thai traditional medicine and its biomarker scopoletin on gastro-esophageal inflammatory models that are related to the claimed pharmacological properties of AFE and/or resembled the human esophagitis or gastric ulcer."7.77Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011)
" This study aimed to determine the role of viable Lactobacillus in the healing of acetic acid-induced chronic gastric ulcer."7.76Yogurt containing Lactobacillus gasseri OLL 2716 (LG21 yogurt) accelerated the healing of acetic acid-induced gastric ulcer in rats. ( Kurakazu, K; Shimizu, K; Uchida, M, 2010)
"To evaluate the role of ALA treatment on the healing of acetic acid-induced gastric ulcer, rats were given ALA (35 mg/kg/day) or saline for 3 days before the induction of ulcer and the treatment was continued twice daily for 2 days (early) or 10 days (late) until they were decapitated."7.75Alpha-lipoic acid improves acetic acid-induced gastric ulcer healing in rats. ( Ercan, F; Erzik, C; Karakoyun, B; Yeğen, BC; Yüksel, M, 2009)
"This study is to investigate therapeutic effect of astaxanthin on acetic acid-induced gastric ulcer in rats."7.75[Therapeutic effect of astaxanthin on acetic acid-induced gastric ulcer in rats]. ( Fu, Y; Ruan, H; Yang, Q; Zhang, Z; Zhu, X, 2009)
" Optimal effective dose of PPSM (25 mg/kg) showed antiulcerogenic activity against acute gastric ulcers (GU) induced by pylorus ligation and aspirin and duodenal ulcer induced by cysteamine but not against ethanol-induced GU."7.75Effect of methanolic extract of Pongamia pinnata Linn seed on gastro-duodenal ulceration and mucosal offensive and defensive factors in rats. ( Agarwal, PK; Dorababu, M; Goel, RK; Goel, S; Joshi, VK; Prabha, T; Singh, A, 2009)
"In the present study, we compared the effects of alpha-tocopherol and probucol, antioxidants, on the healing of acetic acid-induced gastric ulcers in 8-, 48- and 96-week-old rats."7.74Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol. ( Ishihara, M; Ito, M; Kojima, R, 2008)
" In the present study, we examined the effect of alendronate on the healing of acetic acid-induced gastric ulcers in rats and investigated the mechanism involved in this action both in vivo and in vitro using the rat gastric epithelial cell line (RGM1)."7.74Impairment of gastric ulcer healing by alendronate, a nitrogen-containing bisphosphonate, in rats. ( Aihara, E; Amagase, K; Hayashi, S; Nishikawa, K; Takeuchi, K, 2007)
"Gastric ulcers were induced with acetic acid in rats; aspirin was administrated by gavage from day 25 to day 54 after ulcer induction."7.74Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007)
"Aspirin enhance the recurrence of gastric ulcer."7.74Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007)
"To assess the synergistic action of famotidine (FMD) and chlorpheniramine (CPA) on acetic acid-induced chronic gastric ulcer in rats."7.73Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats. ( Chen, C; Qin, Z, 2005)
"The synergistic action of FMD and CPA on acetic acid-induced chronic gastric ulcer in rats decreases the incidence of ulcer and also enhances the healing of ulcer."7.73Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats. ( Chen, C; Qin, Z, 2005)
" Since prostaglandins are inducers of hepatocyte growth factor (HGF), we examined the effect of rebamipide on the expression of HGF, c-met, cyclooxygenase-2 (Cox-2) and subtype of the prostaglandin E2 receptor (EP2) in acetic acid-induced gastric ulcer, a model of human ulcer."7.72Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor. ( Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A, 2003)
" Gastric ulcers were produced by injecting 50 microl of 20% acetic acid into subserosa of the border between the fundic and antral gland areas."7.72Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor. ( Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A, 2003)
"We previously discovered that a 4-wk course of indomethacin delivered to rats with acetic acid ulcers resulted in production of "unhealed gastric ulcers" that persisted for up to 12 wks after treatment cessation."7.72Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats. ( Amagase, K; Okabe, S; Tsukimi, Y; Yokota, M, 2003)
" We investigated the changes in the level of gastric colonization 140 days after inducing gastric ulcer by acetic acid in the antral mucosa of a miniature pig infected with H."7.72Temporal increase in the gastric colonization of Helicobacter pylori after healing of acetic acid-induced gastric ulcer in a miniature pig. ( Iwata, M; Katsuta, M; Kikuchi, I; Koga, T; Okazaki, Y; Sato, K; Shimada, Y; Takahashi, K, 2003)
"In this study, the healing effects of Centella asiatica water extract (CE) and asiaticoside (AC), an active constituent of CE, on acetic acid induced gastric ulcers (kissing ulcers) in rats were examined."7.72The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats. ( Cheng, CL; Guo, JS; Koo, MW; Luk, J, 2004)
"The purpose of this study was to evaluate the healing effect of interleukin-11 (IL-11) on acetic acid-induced gastric ulcer in rats."7.71Mechanism of the antiulcerogenic effect of IL-11 on acetic acid-induced gastric ulcer in rats. ( Fukuda, E; Ito, M; Matsuu, M; Nakashima, M; Nakayama, T; Sekine, I; Shichijo, K; Wen, CY, 2002)
"Acetic acid was perfused into the gastric cavitties of 130 rats to produce animal model of /gastric ulcer."7.71[Expression and activity of cyclooxygenases-1 and -2 in acetic acid induced gastric ulcer in rats]. ( Guo, J; Koo, MW; Wang, J, 2001)
"To investigate the effect of Jianpiyiqi prescription on the expression of heat shock proteins (HSPs) and the changes of HSPs in gastric-ulcerated rats, the rat model of chronic gastric ulcer was induced by acetic acid."7.71Effect of jianpiyiqi prescription on the expression of heat shock proteins in acetic acid-induced chronic gastric ulcer rats. ( Li, G; Luo, S; Tao, X, 2001)
"To investigate the possible role of cyclooxygenase-2 (COX-2) inhibitor NS-398 in formation and healing of acetic acid-induced gastric ulcer in rats."7.71[Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001)
"Fourty eight male Sprague-Dawley rats weighed 160-180 g were perfused with acetic acid into the stomach to induce gastric ulcer and then divided into two groups."7.71[Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001)
"NS-398 inhibits COX-2 activity, thus alleviating inflammatory reaction in acetic acid induced gastric ulcer and averting further damage of tissues."7.71[Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001)
" A mechanistic study of the potentiating effects of cigarette smoking on acetic acid-induced gastric ulceration in rats was hence performed."7.70Mechanistic study of adverse actions of cigarette smoke exposure on acetic acid-induced gastric ulceration in rats. ( Cho, CH; Chow, JY; Ma, L, 1998)
"Based on our previous studies that aspirin (ASA) -induced gastric ulceration in rats can be significantly reduced if the drug is chemically associated with phosphatidylcholine (PC), we undertook the present study to compare gastric ulcer healing rates in rats administered either unmodified or PC-complexed ASA."7.70Phosphatidylcholine-associated aspirin accelerates healing of gastric ulcers in rats. ( Kurinets, A; Lichtenberger, LM, 1998)
"Effect of lafutidine ((+/-)-2-(furfurylsulfinyl)-N-[4-[4-(piperidinomethyl)-2-pyr idyl] oxy-(Z)-2-butenyl] acetamide, FRG-8813), a novel antiulcer agent, on the healing and relapse in acetic acid-induced gastric ulcer in rats was investigated."7.70[Effect of lafutidine, a novel antiulcer agent, on healing and relapse of acetic acid-induced gastric ulcer in rats]. ( Aoyama, M; Arai, Y; Ohnishi, H; Onodera, S; Shibata, M; Tanaka, M; Yamaura, T, 1998)
" at an effective anti-inflammatory dose to rats with pre-existing acetic acid-induced gastric ulcer, NS-398 caused a statistically significant delay of ulcer healing."7.70Effects of novel anti-inflammatory compounds on healing of acetic acid-induced gastric ulcer in rats. ( Dyer, RD; Gilbertsen, RB; Guglietta, A; Kraus, ER; Lesch, CA; Sanchez, B; Schrier, D; Song, Y, 1998)
"To investigate whether or not heparin can accelerate the healing process of acetic acid-induced gastric ulcers in rats and to identify the mechanisms for heparin to produce this effect, so that we can develop a new therapeutic application to heparin besides its traditional anticoagulant activity."7.70Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998)
"Male Sprague-Dawley rats were used to produce acetic acid-induced gastric ulcers."7.70Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998)
"Heparin with the doses used in the present study accelerated the healing of acetic acid-induced gastric ulcers in rats in a dose- and time-dependent manner, and this action was related to its effects to increase the levels of gastric mucosal PGE2 and GMBF as well as to decrease the gastric mucosal MPO activity."7.70Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998)
"The healing of experimental gastric ulcers induced in rats is consistently delayed upon chronic treatment with indomethacin."7.70A new ulcer model, "unhealed gastric ulcers", induced by chronic treatment with indomethacin in rats with acetic acid ulcers. ( Amagase, K; Okabe, S, 1999)
" The pharmacokinetics of the drug were also evaluated after oral administration to rats with acetic acid-induced gastric ulcer (AIURs)."7.70Gastrointestinal absorption of a new reversible proton pump inhibitor, YJA-20379-8, and its pharmacokinetics after oral administration in acetic acid-induced gastric ulcer in rats. ( Chang, MS; Chung, SY; Han, KS; Kim, HJ; Kim, J; Lee, MG, 1999)
" In this study, we examined the effect of pentoxifylline on healing of acetic acid induced gastric ulcers in rats."7.70Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000)
"Pentoxifylline accelerates healing of acetic acid induced gastric ulcer in rats."7.70Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000)
"Rats with gastric ulcer received an intraperitoneal injection of 10 mg/kg pentoxifylline once daily for 14 days or for only the first 7 days or the last 7 days of the 14-day treatment period."7.70Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000)
"To investigate the influence of water extracts of CagA-positive or -negative Helicobacter pylori on healing of chronic gastric ulcers and on connexin formation, proliferation and apoptosis, in acetic acid-induced chronic gastric ulcers in rats."7.70The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000)
"Acetic acid was used to induce chronic gastric ulcers in rats, and a water extract of H."7.70The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000)
"In untreated rats, acetic acid-induced gastric ulcers healed after 14 days and the electrophoretic band corresponding to connexin 32 appeared 4 days after ulcer induction."7.70The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000)
"Effects of treatment with free radical scavengers in the healing process of acetic acid-induced gastric ulcer on the ulcer aggravation induced by indomethacin were investigated."7.69Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats. ( Kondo, M; Matsuyama, K; Naito, Y; Nishimura, S; Yagi, N; Yoshikawa, T, 1995)
"This study was done to elucidate whether rebamipide during the initial period of acetic acid-induced gastric ulcer affected healing and future ulcer relapse."7.69Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine. ( Arakawa, T; Fukuda, T; Kobayashi, K; Watanabe, T; Yamasaki, K, 1995)
"Tobacco cigarette smoke attenuates injury-induced hyperemia, aggravates hypertonic saline-induced mucosal damage, inhibits ulcer margin hyperemia, and increases the size of the acetic acid-induced ulcer in the rat stomach."7.69Misoprostol reverses the inhibition of gastric hyperemia and aggravation of gastric damage by tobacco cigarette smoke in the rat. ( Iwata, F; Leung, FW, 1995)
"The healing of acetic acid-induced gastric ulcer in rats and the effects of cimetidine and calcitonin were investigated with reference to the enzyme activity of both prolylhydroxylase and collagenase as related to histological findings."7.69Wound healing of acetic acid-induced gastric ulcer in rats and the effects of cimetidine and calcitonin, with special reference to prolylhydroxylase and collagenase enzyme activity. ( Arai, M; Komatsu, H; Kurose, I; Maruyama, K; Nakamura, M; Okazaki, I; Tsuchiya, M, 1995)
"The effects of IGN-2098 on the healing process of acetic acid-induced gastric ulcer was investigated in comparison with the other histamine H2-receptor antagonists, famotidine and roxatidine acetate HCl, in rats."7.69[Therapeutic effect of IGN-2098, a new antiulcer drug (H2-antagonist), in the ulcer diminishing period against acetic acid-induced gastric ulcer in rats]. ( Ikarashi, Y; Misaki, N; Ohba, S; Ohbayashi, S; Uchida, M, 1995)
"The effects of cimetidine, omeprazole and atropine sulfate on the healing of acetic acid-induced gastric ulcers in rats with limited food intake time (9:00-10:00 a."7.69Effect of cimetidine and omeprazole on gastric ulcer healing of rats with limited food intake time. ( Ito, M; Kojima, R; Segami, T; Suzuki, Y; Tsukahara, T, 1994)
"To investigate the effect of capsaicin, cimetidine, and in combination, given intragastrically in the healing of acetic acid induced chronic gastric ulcer in the rat."7.69Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996)
"Capsaicin promotes the healing of acetic acid induced gastric ulcer, probably by its gastric hyperaemic effect."7.69Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996)
"Capsaicin protects the gastric mucosa against experimental injury while capsaicin desensitisation reduces the rate of gastric ulcer healing."7.69Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996)
"To clarify the relationship between Helicobacter pylori and the healing of gastric ulcers, we investigated the healing of acetic acid-induced gastric ulcers in the antral mucosa of Japanese monkeys (n = 5) infected with H."7.69Helicobacter pylori infection delays the healing of acetic acid-induced gastric ulcer in Japanese monkeys. ( Fujioka, T; Kodama, R; Kubota, T; Nasu, M; Shuto, R, 1996)
"We found indomethacin aggravates healed gastric ulcers (ulcer relapse) in rats."7.69Prevention of gastric ulcer relapse induced by indomethacin in rats by a mutein of basic fibroblast growth factor. ( Asano, S; Inada, I; Maeda, R; Murakami, I; Sato, F; Satoh, H; Shino, A, 1997)
" Therefore, the aim of this study was to examine the role of collagenase and gelatinases A and B in the development and healing of acetic acid-induced gastric ulcer in rats."7.69Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997)
"Gastric ulcer was induced by injecting 20 microliters glacial acetic acid into gastric wall of rat stomachs."7.69Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997)
"This study examined the relationship between healing of acetic acid-induced chronic gastric ulcer and connexin formation."7.69Relationship between healing of acetic acid-induced chronic gastric ulcer and connexin. ( Fujita, T; Kushima, R; Mine, T, 1997)
" We investigated proliferative activity in the healing process of acetic acid-induced gastric ulcer by immunohistochemical staining of PCNA and 5-bromo-2-deoxyuridine (BrdU), and the two methods were compared."7.68Cell proliferation kinetics in acetic acid-induced gastric ulcer evaluated by immunohistochemical staining of proliferating cell nuclear antigen. ( Hiramatsu, A; Inoue, K; Kitajima, T; Mizuno, T; Nakano, T; Okuhira, M; Tani, K, 1993)
"Effects of troxipide (Ku-54) on various experimental gastric ulcers in rats were studied."7.68[The pharmacodynamics of troxipide on experimental gastric ulcers in rats]. ( Fan, A; Fang, Z; Wang, J; Wang, Y; Zhang, L, 1993)
"To clarify the ability of endoscopic ultrasonography (EUS) to diagnose gastric ulcer, we induced gastric ulcer (19 open ulcers and 11 ulcer scars) by injecting acetic acid into the stomach via an endoscope in 15 dogs."7.68Evaluation of acetic acid-induced gastric ulcers in dogs by endoscopic ultrasonography. ( Chijiiwa, Y; Fujishima, H; Maruoka, A; Misawa, T; Nawata, H, 1993)
"We examined the effect of NC-1300-O-3 on the healing of acetic acid-induced gastric ulcers in male Donryu rats."7.68Effect of NC-1300-O-3 on healing of acetic acid-induced gastric ulcers in rats. ( Inoue, K; Okabe, S; Takagi, K, 1993)
"Repeated administration of indomethacin delays the healing of acetic acid-induced gastric ulcers in rats, but the underlying mechanism remains unclear."7.68Mechanism by which indomethacin delays gastric ulcer healing in the rat: inhibited contraction of the ulcer base. ( Ogihara, Y; Okabe, S, 1993)
"Repeated administration of indomethacin or prednisolone for 2 weeks apparently delayed the healing of initial gastric ulcers induced by acetic acid injection in rats."7.68Effects of indomethacin and prednisolone on the different stages of healing of acetic acid-induced gastric ulcers in the rat. ( Ogihara, Y; Okabe, S, 1993)
"The effect of a proton pump inhibitor, omeprazole (OPZ), in combination with mouse epidermal growth factor (EGF), on the healing of chronic gastric ulcers induced by acetic acid in submandibular glands removed rats (SMR rat) was investigated."7.68[Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats]. ( Imai, S; Itoh, M; Joh, T; Takeuchi, T; Yokoyama, Y, 1992)
"The localization of fibronectin (FN) and laminin (LM) and cellular kinetics of epithelium in acetic acid induced gastric ulcers were examined by immunohistochemistry, comparing fundic glands ulcer with fundic-pyloric border ulcer."7.68[The immunohistochemical study on the recurrent mechanism of acetic acid induced gastric ulcer in rats--extracellular matrix and cellular kinetics]. ( Yagi, K, 1992)
"We investigated the effects of cimetidine and omeprazole on angiogenesis in granulation tissue and on the healing of gastric ulcers induced by acetic acid in rats."7.68Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats. ( Goto, H; Hase, S; Segawa, K; Tsuchida, T; Tsukamoto, Y, 1990)
"To clarify the mechanism of gastric ulcer recurrence, we studied acetic acid-induced gastric ulcers."7.68Evaluation of acetic acid-induced gastric ulcers in rats by scanning acoustic microscopy. ( Goto, H; Hase, S; Mizutani, K; Niwa, Y; Ohashi, S; Tsukamoto, Y, 1991)
"The macroscopic and microscopic effects of 12-sulfodehydroabietic acid monosodium salt (TA-2711, CAS 86408-72-2) on the healing of acetic acid-induced gastric ulcers in rats were compared with those of sucralfate and carbenoxolone."7.68Effects of the new anti-ulcer agent 12-sulfodehydroabietic acid monosodium salt on healing of acetic acid-induced gastric ulcers in rats. ( Iwasaki, H; Magaribuchi, T; Onoda, Y; Tamaki, H, 1991)
"Repeated administration of indomethacin markedly delays spontaneous healing of experimental gastric ulcers induced in rats."7.68Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats. ( Hirose, H; Okabe, S; Takeuchi, K, 1991)
"The present study was designed to investigate the changes in gastric mucosal PGI2 level accompanying the healing of acetic acid-induced gastric ulcers in rats."7.68Healing of acetic acid-induced gastric ulcer and gastric mucosal PGI2 level in rats. ( Irino, O; Kawano, O; Misaki, N; Saitoh, K; Uchida, M, 1990)
"The present study examined the time sequence and histologic and ultrastructural features of the formation and evolution of experimental, acetic acid-induced gastric ulcerations in rats."7.68Vascular and microvascular changes--key factors in the development of acetic acid-induced gastric ulcers in rats. ( Dabros, W; Eltorai, M; Gergely, H; Hollander, D; Krause, WJ; Stachura, J; Tarnawski, A, 1990)
"Epidermal growth factor (EGF) has been shown to enhance healing of experimental gastric ulcers when given subcutaneously or orally in the drinking water."7.68Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat. ( Endoh, K; Imai, S; Itoh, M; Iwai, A; Joh, T; Kawai, T; Matsusako, K; Takeuchi, T; Yasue, N; Yokoyama, Y, 1990)
"Omeprazole, a gastric mucosal proton pump inhibitor, significantly and dose-dependently prevented the delayed healing of acetic acid-induced gastric ulcers in response to repeatedly administered indomethacin to rats."7.68Effect of omeprazole on delayed healing of acetic acid-induced gastric ulcers in rats. ( Nagai, H; Okabe, S; Wang, JY, 1990)
"The anti-ulcer effect of sofalcone, an isoprenyl chalcone derivative, on acetic acid-induced gastric ulcers in rats was studied histologically and histochemically."7.67Effect of 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy) chalcone (sofalcone) on chronic gastric ulcers in rats. ( Arai, I; Kimura, M; Nakane, S; Saziki, R; Tarumoto, Y, 1984)
"The progress of acetic acid-induced gastric ulcers in rats were sequentially observed with an endoscope for 365 days, and the influences of the ulcer-induced site, age and sex on the healing, recurrence and relapse of these ulcers were investigated."7.67[Experimental studies on gastric ulcer (6). Endoscopical evaluation of healing processes of acetic acid ulcer in rats (2): Healing, recurrence and relapse of ulcer]. ( Fukawa, K; Irino, O; Kawano, O; Misaki, N; Uchida, M, 1984)
"In an attempt to elucidate the role of granulation vessels in the healing of gastric ulcer, healing and angiogenesis in granulation tissue of acetic acid ulcers were studied in rats."7.67Effects of prednisolone and human epidermal growth factor on angiogenesis in granulation tissue of gastric ulcer induced by acetic acid. ( Hase, S; Nakazawa, S; Segawa, K; Tsukamoto, Y, 1989)
"The present study was undertaken to elucidate the role of mucous secreting cells in the healing of acetic acid-induced gastric ulcers in rats."7.67Physiological significance of mucous neck cell-type mucins in the healing of acetic acid-induced gastric ulcers in rats. ( Hashikura, Y; Ichikawa, H; Katsuyama, T; Kobayashi, C; Sugiyama, A, 1989)
"We examined the changes in prolylhydroxylase (PH) and interstitial collagenase (CA) activities in the healing of acetic acid-induced gastric ulcers in rats."7.67Prolylhydroxylase and collagenase activities in the healing of acetic acid-induced gastric ulcers in rats and the effects of cimetidine and elcatonin. ( Komatsu, K; Kurose, I; Maruyama, K; Oda, M; Okazaki, I; Tsuchiya, M, 1989)
"We investigated the roles of endogenous leukotrienes (LTs) and prostaglandins (PGs) in the healing of gastric ulcers induced by acetic acid in rats."7.67Roles of endogenous leukotrienes and prostaglandins in the healing of gastric ulcers induced by acetic acid in rats. ( Arakawa, T; Fukuda, T; Kobayashi, K; Nakamura, H; Nebiki, H; Torii, Y, 1989)
"Changes in the pH gradient and thickness of the mucus gel layer in the healing of acetic acid-induced gastric ulcers in rats were investigated."7.67Role of the mucus gel layer in the healing of acetic acid-induced gastric ulcers in rats. ( Kawano, O; Matsueda, K; Misaki, N; Muraoka, A; Uchida, M; Umeda, N, 1989)
"We examined the effect of human epidermal growth factor (hEGF) on the healing rate of gastric ulcers induced in rats."7.67Effects of human epidermal growth factor on natural and delayed healing of acetic acid-induced gastric ulcers in rats. ( Kuwahara, Y; Okabe, S, 1989)
"We examined the mechanism by which repeated administration of indomethacin significantly delays the natural healing of experimental gastric ulcers induced in rats."7.67Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin. ( Okabe, S; Takeuchi, K; Wang, JY; Yamasaki, S, 1989)
"A metalloproteinase was extracted from a medium of cultured gastric tissues following acetic acid-induced ulcer or taurocholic acid-induced gastritis, and the enzyme was partially purified by Sephadex G-200 column chromatography."7.67Production of metalloproteinase in gastric tissue with acetic acid-induced ulcer or taurocholic acid-induced gastritis. ( Ishikura, Y; Mori, Y; Murakami, S; Nakanishi, J; Tsuchiya, S, 1987)
"Chronic gastric ulcers were produced by injection of 20% acetic acid (0."7.67Effects of trimoprostil on healing and recurrence of acetic acid-induced gastric ulcer in rats. ( Nakamura, K; Umeda, Y, 1986)
"Ulcers were induced by serosal application of 80 % acetic acid to the stomach of rats anaesthetized with 50 mg/kg thiopentone sodium and treatment was given three times daily."5.46Effects of quinine on gastric ulcer healing in Wistar rats. ( Adeniyi, OS; Friday, ET; Makinde, OV; Olaleye, SB, 2017)
"Gastric ulcers was induced in the animals of 12 groups with one untreated group being left as the control (Group I - control; given normal saline (NS))."5.46Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017)
"Gastric ulcers were induced by the serosal application of 100% acetic acid, and the areas of the ulcers were measured thereafter."5.39NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4(+)VEGFR1(+) cells to the ulcer granulation tissues. ( Ae, T; Amano, H; Eshima, K; Hosono, K; Ito, Y; Katada, C; Koizumi, W; Majima, M; Minamino, T; Ohno, T; Sato, T; Shibuya, M; Suzuki, T, 2013)
"Aspirin enhance the recurrence of gastric ulcer."5.34Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007)
"Ulcer recurrence and poor healing may be critically important to the development of serious gastrointestinal complications in patients with long-term non-steroid anti-inflammatory drugs (NSAIDs)."5.34Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007)
"Gastric ulcers were induced with acetic acid in rats; aspirin was administrated by gavage from day 25 to day 54 after ulcer induction."5.34Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007)
"Gastric ulcers were induced in male SD rats by serosal application of acetic acid for 60 sec."5.34Effect of dopamine on the healing of acetic acid-induced gastric ulcers in rats. ( Amagase, K; Nishikawa, K; Takeuchi, K, 2007)
"Gastric ulcer is a source of visceral pain."5.33Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006)
"Gastric ulcers were induced by luminal application of 60% acetic acid under surgical conditions."5.33Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006)
"Gastric ulcers were produced by injecting 50 microl of 20% acetic acid into subserosa of the border between the fundic and antral gland areas."5.32Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor. ( Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A, 2003)
"The gastric ulcer was induced endoscopically with 1 mL of 40% acetic acid 12 days after inoculation of H."5.32Temporal increase in the gastric colonization of Helicobacter pylori after healing of acetic acid-induced gastric ulcer in a miniature pig. ( Iwata, M; Katsuta, M; Kikuchi, I; Koga, T; Okazaki, Y; Sato, K; Shimada, Y; Takahashi, K, 2003)
"Gastric ulcers were induced in male Wistar rats by applying acetic acid to the fundus of the stomach."5.31Mechanism of the antiulcerogenic effect of IL-11 on acetic acid-induced gastric ulcer in rats. ( Fukuda, E; Ito, M; Matsuu, M; Nakashima, M; Nakayama, T; Sekine, I; Shichijo, K; Wen, CY, 2002)
"Acetic acid was perfused into the gastric cavitties of 130 rats to produce animal model of /gastric ulcer."5.31[Expression and activity of cyclooxygenases-1 and -2 in acetic acid induced gastric ulcer in rats]. ( Guo, J; Koo, MW; Wang, J, 2001)
"Pentoxifylline has many anti-inflammatory properties including inhibition of production of tumor necrosis factor alpha (TNF-alpha)."5.31Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000)
"In untreated rats, acetic acid-induced gastric ulcers healed after 14 days and the electrophoretic band corresponding to connexin 32 appeared 4 days after ulcer induction."5.31The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000)
"Acetic acid was used to induce chronic gastric ulcers in rats, and a water extract of H."5.31The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000)
"In acetic acid-treated rats, this activity increased to 2."5.30Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997)
"Gastric ulcer was induced by injecting 20 microliters glacial acetic acid into gastric wall of rat stomachs."5.30Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997)
"Pretreatment with allopurinol (Allo, 5 mg/kg, i."5.30Mechanistic study of adverse actions of cigarette smoke exposure on acetic acid-induced gastric ulceration in rats. ( Cho, CH; Chow, JY; Ma, L, 1998)
"Gastric ulcers were induced in anesthetized rats by briefly exposing the mucosal surface to 0."5.30Phosphatidylcholine-associated aspirin accelerates healing of gastric ulcers in rats. ( Kurinets, A; Lichtenberger, LM, 1998)
" Heparin in the doses of 100, 500, and 1000 U/kg were administered intravenously through the tail vein once daily, starting 1 day after ulcer induction for 7 days in the dose-response experiment or heparin 1000 U/kg at a time schedule of 3, 5, and 7 days in the time-response study, respectively."5.30Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998)
" The results suggest that modification of the oral dose of YJA-20379-8 may not be required in gastric ulcer patients if the present rat pharmacokinetic data could be extrapolated to man."5.30Gastrointestinal absorption of a new reversible proton pump inhibitor, YJA-20379-8, and its pharmacokinetics after oral administration in acetic acid-induced gastric ulcer in rats. ( Chang, MS; Chung, SY; Han, KS; Kim, HJ; Kim, J; Lee, MG, 1999)
"Gastric ulcers were produced on the anterior wall of the stomach of male Sprague-Dawley rats by submucosal injection of 20% acetic acid."5.29Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats. ( Kondo, M; Matsuyama, K; Naito, Y; Nishimura, S; Yagi, N; Yoshikawa, T, 1995)
"Gastric ulcers were produced 5 days after submucosal injection of 20% acetic acid (0."5.29Effect and mechanism of sucralfate on healing of acetic acid-induced gastric ulcers in rats. ( Ogihara, Y; Okabe, S, 1993)
"The influence of KU-1257 on the recurrence and relapse of acetic acid ulcers in rats was investigated grossly and histologically in comparison with that of cimetidine."5.29[Influence of KU-1257 on the recurrence and relapse of acetic acid-induced chronic gastric ulcers in rats]. ( Kobayashi, F; Ohkubo, H; Ohsawa, A; Sekiguchi, H; Taga, F, 1996)
"The effect of a proton pump inhibitor, omeprazole (OPZ), in combination with mouse epidermal growth factor (EGF), on the healing of chronic gastric ulcers induced by acetic acid in submandibular glands removed rats (SMR rat) was investigated."5.28[Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats]. ( Imai, S; Itoh, M; Joh, T; Takeuchi, T; Yokoyama, Y, 1992)
" Chronic administration of hydrocortisone sodium phosphate resulted in a significant delay of ulcer healing induced by acetic acid."5.28Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991)
"Chronic gastric ulcers were produced in male Wistar rats, weighing 180 g, by the application of 100% acetic acid."5.28Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991)
"Gastric ulcers were induced 5 days after submucosal injection of an acetic acid solution into the stomachs of rats."5.28Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats. ( Hirose, H; Okabe, S; Takeuchi, K, 1991)
" This suggests that further stimulation of ulcer healing may be expected if EGF is given with an acid-suppressive agent or with an agent allowing EGF to remain in rat gastric lumen at high concentrations."5.28Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat. ( Endoh, K; Imai, S; Itoh, M; Iwai, A; Joh, T; Kawai, T; Matsusako, K; Takeuchi, T; Yasue, N; Yokoyama, Y, 1990)
"Gastric ulcers were induced by subserosal injection of acetic acid, and confirmed by endoscopy on the third day."5.28Prolylhydroxylase and collagenase activities in the healing of acetic acid-induced gastric ulcers in rats and the effects of cimetidine and elcatonin. ( Komatsu, K; Kurose, I; Maruyama, K; Oda, M; Okazaki, I; Tsuchiya, M, 1989)
"Gastric ulcers were produced 5 days after injecting 20% acetic acid (0."5.28Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin. ( Okabe, S; Takeuchi, K; Wang, JY; Yamasaki, S, 1989)
"Chronic gastric ulcers were produced by injection of 20% acetic acid (0."5.27Effects of trimoprostil on healing and recurrence of acetic acid-induced gastric ulcer in rats. ( Nakamura, K; Umeda, Y, 1986)
"The present study aimed to observe the healing effect of QWZT on acetic acid-induced gastric ulcer in a rat model and to preliminarily elucidate its possible therapeutic mechanism from the perspective of host intestinal microbiota and metabolism."4.84Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats. ( An, Y; Jiang, S; Lin, H; Liu, J; Wang, C; Wang, F; Wang, G; Zhang, J; Zheng, H; Zheng, W, 2024)
"The Wistar male rats (7 weeks old; weight 180-200 g) were randomly divided into normal control group (NC), acetic acid-induced gastric ulcer group (GU), and QWZT treatment group (High dose: 1250 mg/kg/day, Middle dose: 625 mg/kg/day, Low dose: 312."4.84Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats. ( An, Y; Jiang, S; Lin, H; Liu, J; Wang, C; Wang, F; Wang, G; Zhang, J; Zheng, H; Zheng, W, 2024)
" Apart from that, FMT improved acetic acid-induced gastric ulcers in rats."4.84Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats. ( An, Y; Jiang, S; Lin, H; Liu, J; Wang, C; Wang, F; Wang, G; Zhang, J; Zheng, H; Zheng, W, 2024)
"QWZT improved acetic acid-induced gastric ulcers in rats by remodeling intestinal microbiota and regulating host metabolism."4.84Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats. ( An, Y; Jiang, S; Lin, H; Liu, J; Wang, C; Wang, F; Wang, G; Zhang, J; Zheng, H; Zheng, W, 2024)
"Rats (females) were treated with AEC (3, 30 or 300 mg/kg) prior to the ethanol or piroxicam-induced gastric ulcers."4.12Gastroprotective and gastric healing effects of the aqueous extract of Casearia sylvestris in rodents: Ultrasound, histological and biochemical analyzes. ( Aires, BA; Boeing, T; Cury, BJ; da Costa Zanatta, ME; de Oliveira, BMM; Dos Santos, AC; Mota da Silva, L; Roman Junior, WA; Serpa, PZ; Somensi, LB; Steffler, AM; Venzon, L, 2022)
"The AEC (30 or 300 mg/kg) prevented ulcers in the ethanol- and piroxicam-induced acute."4.12Gastroprotective and gastric healing effects of the aqueous extract of Casearia sylvestris in rodents: Ultrasound, histological and biochemical analyzes. ( Aires, BA; Boeing, T; Cury, BJ; da Costa Zanatta, ME; de Oliveira, BMM; Dos Santos, AC; Mota da Silva, L; Roman Junior, WA; Serpa, PZ; Somensi, LB; Steffler, AM; Venzon, L, 2022)
"Gastric healing effects, underlining mechanisms, and behavioral changes were measured in80% acetic acid-induced gastric ulcer model in rats receiving GE by oral (30 mg/kg) or inhaled route (1 mg/L of air/min); whereas the effects of GE to avoid ulcer recurrence was evaluated in mice submitted to 10% acetic acid plus IL-1β ulcer."4.12Geraniol accelerates the gastric healing, minimizes ulcers recurrence, and reduces anxiolytic-like behavior in ulcerated rodents by oral or inhaled route. ( Boeing, T; Cazarin, CA; da Silva, LM; de Souza, MM; Dos Santos França, TC; Longo, B; Mariano, LNB; Mariott, M; Meurer, MC; Pereira, LN; Somensi, LB; Venzon, L, 2022)
"Geraniol (GE) is dietary acyclic monoterpene alcohol found in essential oils from aromatic plants with therapeutic value against gastric ulcers already described."4.12Geraniol accelerates the gastric healing, minimizes ulcers recurrence, and reduces anxiolytic-like behavior in ulcerated rodents by oral or inhaled route. ( Boeing, T; Cazarin, CA; da Silva, LM; de Souza, MM; Dos Santos França, TC; Longo, B; Mariano, LNB; Mariott, M; Meurer, MC; Pereira, LN; Somensi, LB; Venzon, L, 2022)
" The anthocyanidin effects were examined in gastric ulcer mouse models induced by ethanol, non-steroidal anti-inflammatory drugs (NSAIDs), ischemia-reperfusion (IR), acetic acid and duodenal ulcer induced by polypharmacy."4.02Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation. ( Dos Santos, RC; Fagundes, FL; Pereira, QC; Zarricueta, ML, 2021)
" trimera (EOBT) against gastric ulcer lesions caused by absolute ethanol and acetic acid, respectively, and to identify the mechanism of action of this essential oil in male Wistar rats."4.02The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity. ( Assunção, R; Besten, MA; Bueno, G; Chavez Rico, SL; Emílio-Silva, MT; Heiden, G; Hiruma-Lima, CA; Justulin, LA; Lima Camargo, AC; Machado da Rocha, LR; Nunes, DS; Ohara, R; Périco, LL; Rodrigues, VP, 2021)
" speciosa accelerated healing of gastric ulcers even in presence of indomethacin, while decreasing bacterial loads in rats' stomachs."4.02Eremomastax speciosa (Hochst.) Cufod. counteracts the delaying effect of indomethacin on Helicobacter pylori-associated chronic gastric ulcers healing. ( Amang, AP; Choudhary, MI; Enow-Orock, GE; Maharjan, R; Mezui, C; Siwe, GT; Tan, PV; Zondegoumba, NE, 2021)
" Chronic gastric ulcer in rats was modeled using glacial acetic acid."3.96A new derivative of acetylsalicylic acid and carnosine: synthesis, physical and chemical properties, biological activity. ( Andreeva, LA; Fedorova, TN; Kulichenkova, KN; Kulikova, OI; Lopachev, AV; Lopacheva, OM; Migulin, VA; Nagaev, IY; Stvolinsky, SL; Trubitsina, IE, 2020)
" To elucidate the mechanism responsible for delayed healing of the gastric injury in old age, we analyzed the expression of these markers in rats of different months during the healing of an acetic acid-induced gastric ulcer."3.96Immunohistochemical Studies of Age-Related Changes in Cell Proliferation and Angiogenesis during the Healing of Acetic Acid-Induced Gastric Ulcers in Rats. ( Ajayi, AF; Olaleye, SB, 2020)
" After the period of exposure, chronic gastric ulcer were induced by intraluminal application of 50% acetic acid."3.96Exposure to Mosquito Coil Smoke Delays Healing of Acetic Acid Induced Gastric Ulcer in Male Wistar Rats. ( Odukanmi, A; Olaleye, SB; Olanrewaju, TR; Salami, AT, 2020)
"We used acetic acid to induce gastric ulcer in Sprague Dawley rats."3.96Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157. ( Li, N; Lu, Q; Shi, R; Shrestha, SM; Tan, J; Wei, M; Wu, G; Wu, H; Zhang, Z, 2020)
"Although Clopidogrel is safe in healthy volunteers, it can induce recurrence of gastric ulcers in high-risk patients."3.96Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157. ( Li, N; Lu, Q; Shi, R; Shrestha, SM; Tan, J; Wei, M; Wu, G; Wu, H; Zhang, Z, 2020)
" This study evaluated its healing efficacy and the mechanism involved using the rat model of chronic gastric ulcer induced by serosal injection of 80% acetic acid in vivo, and human gastric adenocarcinoma cells (AGS) in vitro."3.91(-)-Myrtenol accelerates healing of acetic acid-induced gastric ulcers in rats and in human gastric adenocarcinoma cells. ( Braga, AD; Lopes, MTP; Nunes, PIG; Oliveira, FTB; Oliveira, RCM; Rao, VS; Santos, FA; Santos, VG; Silva, ACA; Sousa, DP; Viana, AFSC; Viana, DA, 2019)
"The gastroprotective property of (-)-myrtenol, a monoterpenoid, has been demonstrated previously against acute gastric ulceration induced by ethanol."3.91(-)-Myrtenol accelerates healing of acetic acid-induced gastric ulcers in rats and in human gastric adenocarcinoma cells. ( Braga, AD; Lopes, MTP; Nunes, PIG; Oliveira, FTB; Oliveira, RCM; Rao, VS; Santos, FA; Santos, VG; Silva, ACA; Sousa, DP; Viana, AFSC; Viana, DA, 2019)
"o) on chronic gastric ulcer induced by acetic acid in rats, a model that resembles the ulcer in humans."3.91Hesperidin, a citrus flavanone glycoside, accelerates the gastric healing process of acetic acid-induced ulcer in rats. ( Boeing, T; Bolda Mariano, LN; Cechinel-Filho, V; da Silva, LM; de Andrade, SF; de Souza, P; Dos Santos, AC; Longo, B; Mariott, M; Pezzini, BC; Somensi, LB, 2019)
"Gastric ulceration was experimentally generated by administration of single oral doses of indomethacin (30 mg/kg) to fasted rats."3.91Antiulcer activity of Cyperus alternifolius in relation to its UPLC-MS metabolite fingerprint: A mechanistic study. ( Abdallah, HMI; Efferth, T; Elshamy, AI; Farag, MA; Farrag, ARH; Gendy, AEGE; Hegazy, MF; Khattab, AR; Mohamed, TA, 2019)
"Preclinical Research & Development The objective of the present study was to evaluate the tapentadol-diclofenac combination in three dose-ratios in the mouse acetic acid-induced visceral pain and their ulcerogenic activity on the stomachal mucous."3.88Assessment of the antinociceptive and ulcerogenic activity of the tapentadol-diclofenac combination in rodents. ( Alonso-Castro, ÁJ; Granados-Soto, V; Isiordia-Espinoza, MA; Sánchez-Enriquez, S; Zapata-Morales, JR, 2018)
"In this rat study involving males, intact (cycling) females, and ovariectomized females, gastric ulcers were induced using acetic acid."3.88Sex-specific effects of ( Bueno, G; Camargo, ACL; da Rocha, LRM; da Silva, LM; de Andrade, SF; Dos Santos, C; Dos Santos, RC; Hiruma-Lima, CA; Justulin Júnior, LA; Nunes, VVA; Ohara, R; Périco, LL; Rodrigues, VP; Steimbach, VMB; Vilegas, W, 2018)
"This study was conducted to investigate the effects of nitric oxide (NO) in acetic acid-induced gastric ulcer of rats and the underlying mechanisms."3.85Nitric oxide donor protects against acetic acid-induced gastric ulcer in rats via S-nitrosylation of TRPV1 on vagus nerve. ( Gong, L; Han, T; Li, J; Liu, C; Tang, Y; Xue, B; Yu, X, 2017)
"Background This study aimed to evaluate the effects of the position of an acetic acid-induced gastric ulcer and the effects of prokinetic drugs on gastric emptying."3.85Gastric emptying after artificial ulceration in rats: differences due to the site of the ulcer and the effects of prokinetic drugs. ( Kobayashi, O; Shimizu, K; Uchida, M, 2017)
"Carbon monoxide (CO), a gaseous mediator produced by haem oxygenases (HOs), has been shown to prevent stress-, ethanol-, aspirin- and alendronate-induced gastric damage; however, its role in gastric ulcer healing has not been fully elucidated."3.85Carbon monoxide released from its pharmacological donor, tricarbonyldichlororuthenium (II) dimer, accelerates the healing of pre-existing gastric ulcers. ( Brzozowski, T; Chmura, A; Ginter, G; Hubalewska-Mazgaj, M; Kwiecien, S; Magierowska, K; Magierowski, M; Pajdo, R; Sliwowski, Z, 2017)
"The purpose of our investigative work has been to determine whether there can be therapeutic roles in the administration of sildenafil citrate, heparin and several neuropeptides on an animal model where gastric ulcers were induced with acetic acid, and to compare their efficacy."3.85Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017)
"Overall the data indicate that low dose heparin, and especially sildenafil citrate and neuropeptides, can be used clinically as an alternative approach in the treatment of the gastric ulcer."3.85Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017)
""Unhealed gastric ulcers" were induced using indomethacin following the establishment of acetic-acid-induced chronic gastric ulcers."3.85Healing and Antisecretory Effects of Aqueous Extract of ( Amang, AP; Emakoua, J; Enow-Orock, GE; Mbah, G; Mezui, C; Nkwengoua, EZ; Siwe, GT; Tan, PV, 2017)
"In order to elucidate the contribution of cycloxygenase (COX) enzymes in the anti-oxidant and anti-inflammatory mechanisms of nesfatin-1, which improves the healing process of chronic gastric ulcers, either acetic acid (80%; ulcer groups; n = 40) or saline (control groups; n = 40) was applied to the serosal surface of male Sprague Dawley rats' stomachs for 1 min."3.85Anti-inflammatory effects of nesfatin-1 on acetic acid-induced gastric ulcer in rats: involvement of cyclo-oxygenase pathway. ( Cantali-Ozturk, C; Demirci, EK; Kolgazi, M; Ozdemir-Kumral, ZN; Sirvanci, S; Yegen, BC; Yuksel, M, 2017)
"The model of gastric ulcer was imitated by acetic acid in rats."3.83[Study on Variation of Gastroprotective Effect of Atractylodes lancea Rhizome Before and After Processing]. ( Cai, Q; Jia, TZ; Yu, Y, 2016)
"The gastroprotective effect of Atractylodes lancea rhizome was enhanced after stir-frying with wheat bran in the rat model of gastric ulcer induced by acetic acid."3.83[Study on Variation of Gastroprotective Effect of Atractylodes lancea Rhizome Before and After Processing]. ( Cai, Q; Jia, TZ; Yu, Y, 2016)
" This study evaluated the mechanisms involved in the gastric ulcer healing of the hydroalcoholic extract from green tea (GEt), its ethyl acetate fraction, (GEAc) and epigallocatechin gallate (EGCG) using the model of acetic acid-induced gastric ulcer in rats."3.83Healing mechanisms of the hydroalcoholic extract and ethyl acetate fraction of green tea (Camellia sinensis (L.) Kuntze) on chronic gastric ulcers. ( Baggio, CH; Borato, DG; da Silva, LM; de Souza, LM; Iacomini, M; Maria-Ferreira, D; Scoparo, CT; Werner, MF, 2016)
"This research was performed to explore the protective effect of cod skin collagen peptides (CCP) on gastric ulcer induced by acetic acid."3.83Protective Effect of Cod (Gadus macrocephalus) Skin Collagen Peptides on Acetic Acid-Induced Gastric Ulcer in Rats. ( Hou, H; Li, B; Niu, H; Wang, Z; Zhang, Z, 2016)
" The gastroprotective and ulcer healing activities of HEPu were evaluated using acidified ethanol (acute) and acetic acid (chronic) gastric ulcer models in rodents."3.83Piper umbellatum L.: A medicinal plant with gastric-ulcer protective and ulcer healing effects in experimental rodent models. ( Balogun, SO; da Silva Junior, IF; Damazo, AS; de Oliveira, RG; Martins, DTO, 2016)
" Models of acute gastric ulcer induction by ethanol and indomethacin and of chronic ulcer by acetic acid were used."3.81Antiulcerogenic activity of Carica papaya seed in rats. ( Argadoña, EJ; Cardoso, CA; Carollo, CA; Carrasco, V; Cordeiro, KW; Freitas, Kde C; Pinto, LA, 2015)
"The model of gastric ulcer was imitated by acetic acid in rats, and AL was gavaged."3.81Comparison of the anti-ulcer activity between the crude and bran-processed Atractylodes lancea in the rat model of gastric ulcer induced by acetic acid. ( Cai, Q; Jia, TZ; Jiang, N; Ma, MY; Min, DY; Yu, Y; Yuan, Y, 2015)
"In order to demonstrate the possible protective effects of estrogen receptor (ER)-α and ERβ receptor subtypes in the pathogenesis of colonic and gastric oxidant damage, experimental ulcer and colitis were induced by acetic acid, and the animals were randomly divided as colitis, ulcer, and their corresponding non-ulcer and non-colitis control groups."3.80Estrogen alleviates acetic acid-induced gastric or colonic damage via both ERα- and ERβ-mediated and direct antioxidant mechanisms in rats. ( Ercan, F; Kumral, ZN; Memi, G; Yeğen, BC, 2014)
"The gastric ulcer model were established by acetic acid, water-immersion stress, aspirin induction, pyloric ligation in rats, in order to observe the effect of Weiyangning pills against experimental gastric ulcer and study its effect on the content of nitric oxide (NO) and epidermal growth factor (EGF), gastric mucosal blood flow, the content of PGE2, gastric secretion, gastric acid content and the activity of pepsin."3.79[Study on efficacy and mechanism of weiyangning pills against experimental gastric ulcer]. ( Cao, HY; Huang, P; Liu, J; Wen, S; Wu, QH; Xu, JJ, 2013)
" AT and 6-HL exhibited anti ulcer activity in experimentally induced ulcer models including cold restraint stress (CRU), alcohol (AL), pylorus ligation-induced gastric ulcer (PL) models and they also showed ulcer healing effect in chronic acetic acid-induced ulcer model (AC)."3.79Arbortristoside-A and 7-O-trans-cinnamoyl-6β-hydroxyloganin isolated from Nyctanthes arbortristis possess anti-ulcerogenic and ulcer-healing properties. ( Barthwal, MK; Mishra, V; Narender, T; Palit, G; Pandeti, S; Pandey, HP; Shukla, A, 2013)
"Gastric ulcers were induced by the serosal application of 100% acetic acid, and the areas of the ulcers were measured thereafter."3.79NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4(+)VEGFR1(+) cells to the ulcer granulation tissues. ( Ae, T; Amano, H; Eshima, K; Hosono, K; Ito, Y; Katada, C; Koizumi, W; Majima, M; Minamino, T; Ohno, T; Sato, T; Shibuya, M; Suzuki, T, 2013)
"The effect of fumonisin B1, an inhibitor of ceramide synthase, and of d,l,-threo-1-phenyl-2-hexadecanoylamino-3-morpholino-1-propanol (PPMP) and N-butyldeoxynojirimycin (NB-DNJ), both inhibitors of glucosylceramide synthase, on the accumulation of ceramide and formation of gastric ulcer were examined in the rat model of acetic acid-induced gastric ulcer."3.79Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. ( Hibi, T; Miura, S; Mizushima, T; Nagata, H; Nakashita, M; Suzuki, H; Taki, T; Uehara, K, 2013)
"Fumonisin B1 attenuated acetic acid-induced gastric ulcer formation, associated with a decrease in the number of apoptotic cells."3.79Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. ( Hibi, T; Miura, S; Mizushima, T; Nagata, H; Nakashita, M; Suzuki, H; Taki, T; Uehara, K, 2013)
"We evaluate the curative efficacy of the ethanolic extract (EET) of roots from Arctium lappa (bardana) in healing of chronic gastric ulcers induced by 80% acetic acid in rats and additionally studies the possible mechanisms underlying this action."3.79Ethanolic extract of roots from Arctium lappa L. accelerates the healing of acetic acid-induced gastric ulcer in rats: Involvement of the antioxidant system. ( Allemand, A; André, E; Baggio, CH; Cipriani, TR; da Silva, LM; Dartora, N; de Souza, LM; Dos Santos, AC; Marques, MC; Mendes, DA; Werner, MF, 2013)
" In carrageenan-induced rat paw oedema test, compound 2c and 2f exhibited good anti-inflammatory effect at 3rd h, whereas compounds 2c, 2e, 2d, 2g and 2h showed activity in croton oil induced ear oedema assay in mice."3.78Fluorine bearing sydnones with styryl ketone group: synthesis and their possible analgesic and anti-inflammatory activities. ( Deshpande, SR; Pai, KV, 2012)
" The acetic acid-induced gastric ulcer model, Western blotting assay (COX-1, COX-2 and EGF) and immunohistochemical localization of HSP-70, PCNA and COX-2 were also used to evaluate the Rhizophora mangle healing properties."3.78Mechanisms of action underlying the gastric antiulcer activity of the Rhizophora mangle L. ( Almeida, AC; da Silva, MA; da Silva, MS; de-Faria, FM; Dunder, RJ; Luiz-Ferreira, A; Pellizzon, CH; Rozza, AL; Souza-Brito, AR; Takayama, C; Toma, W; Vilegas, W, 2012)
"Application of acetic acid topically to the mucosal or serosal side of the stomach has been well used to create a chronic gastric ulcer model."3.78Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model. ( Cao, H; Chen, D; Johannessen, H; Kodama, Y; Okabe, S; Takahashi, R; Wang, TC; Zhao, CM, 2012)
" Severe necrosis in the cancer was observed in the side exposing to acetic acid, but not in the control side, shortly after the treatment (i."3.78Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model. ( Cao, H; Chen, D; Johannessen, H; Kodama, Y; Okabe, S; Takahashi, R; Wang, TC; Zhao, CM, 2012)
"Topical application of acetic acid either from mucosal or serosal surface promptly caused the necrosis of tumor, suggesting the potential approach of this simple and reliable method as a cytoreductive treatment of gastric cancer in patients through endoscopy or laparoscopy."3.78Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model. ( Cao, H; Chen, D; Johannessen, H; Kodama, Y; Okabe, S; Takahashi, R; Wang, TC; Zhao, CM, 2012)
"The preventive and healing properties of Croton urucurana bark methanol extract (CUE) were evaluated in experimental models of acute (ethanol and indomethacin) and chronic (acetic acid) gastric ulcers."3.78Antiulcerogenic effect of Croton urucurana Baillon bark. ( Aparecida Pinto, L; de Cássia Freitas, K; Faloni de Andrade, S; Leite Kassuya, CA; Nazari Formagio, AS; Wolff Cordeiro, K, 2012)
"To observe the effects and mechanisms of Pongamia pinnata root flavonoids (PRF) on the experimental gastric ulcer induced by acetic acid and to study the mechanism of PRF on the quality of ulcer healing."3.78[Effect of Pongamia pinnata root flavonoids on the quality of ulcer healing and expression of EGF and TGF-alpha in the rat model of gastric ulcer induced by acetic acid]. ( Huang, XZ; Liu, KY; Zhu, Y, 2012)
"The models were established by acetic acid erosion, the quality of ulcer healing of PRF on the model of gastric ulcer were observed."3.78[Effect of Pongamia pinnata root flavonoids on the quality of ulcer healing and expression of EGF and TGF-alpha in the rat model of gastric ulcer induced by acetic acid]. ( Huang, XZ; Liu, KY; Zhu, Y, 2012)
" The pharmacological activity of AFE and pure scopoletin at the same equivalent dose present in AFE was investigated in rat on gastro-esophageal inflammatory models (acid reflux esophagitis, acute gastritis induced by ethanol and serotonin, and chronic gastric ulcer induced by acetic acid); gastric biochemical parameters and gastrointestinal motility."3.77Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011)
"50 g/kg) significantly prevented the formation of acid reflux esophagitis, reduced the formation of ethanol-induced acute gastric lesions, suppressed the development of gastric lesions in response to serotonin, and accelerated the healing of acetic acid-induced chronic gastric ulcer in rats with equal potency to those obtained by standard antisecretory agents (ranitidine and lansoprazole)."3.77Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011)
" (Rubiaceae) fruit, commonly known as "Noni", in an aqueous extract preparation (AFE) as used in Thai traditional medicine and its biomarker scopoletin on gastro-esophageal inflammatory models that are related to the claimed pharmacological properties of AFE and/or resembled the human esophagitis or gastric ulcer."3.77Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011)
" The acetic acid-induced gastric ulcer model and Western Blot assay (COX-2 and EGF) were also used to evaluate the OEH healing capacity."3.77Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae). ( de Almeida, AC; de-Faria, FM; Dunder, RJ; Hiruma-Lima, CA; Luiz-Ferreira, A; Manzo, LP; Pellizzon, CH; Rehen, CS; Rozza, AL; Salvador, MJ; Socca, EA; Souza-Brito, AR; Takayama, C; Valim-Araújo, Dde A, 2011)
" They have been tested for analgesic activity by acetic acid induced writhing in mice and for anti-inflammatory activity by carrageenan induced rat paw edema at 100 mg/kg body weight p."3.77Design and synthesis of certain mesoionic sydnonyl styrylketones as potential nonsteroidal antiinflammatory agents. ( Deshpande, SR; Pai, KV; Pai, RS, 2011)
"Chronic gastric ulcer was induced by an injection of 100% glacial acetic acid into the submucosal layer of the glandular stomach, then the area of all ulcers was added together as the ulcer index and inhibition rate of ulcer was calculated."3.77Activity of DBXX granules on anti-gastric ulcer and decreasing the side effect of chemotherapy in S180 tumor-bearing mice. ( Cao, Y; Han, N; Lin, X; Liu, Z; Xue, R; Yin, J, 2011)
" Six weeks following streptozotocin or saline injection, gastric ulcers were induced by serosal application of acetic acid."3.77Role of activation of 5'-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats. ( Baraka, AM; Deif, MM, 2011)
"The potential utility of 5'-adenosine monophosphate-activated protein kinase (AMPK)-activating agents, such as metformin, in inducing angiogenesis, could be a promising approach to promote healing of gastric ulcers complicated by diabetes mellitus."3.77Role of activation of 5'-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats. ( Baraka, AM; Deif, MM, 2011)
"Administration of metformin, but not pioglitazone, resulted in a significant decrease in the gastric ulcer area, a significant increase in epithelial regeneration assessed histologically, a significant increase in the number of microvessels in the ulcer margin, a significant increase in gastric vascular endothelial growth factor concentration and gastric von Willebrand factor as well as a significant increase in gastric phospho-AMPK."3.77Role of activation of 5'-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats. ( Baraka, AM; Deif, MM, 2011)
" The antiulcer effect of an extract from cochinchina momordica seeds (SK-MS10) was evaluated in a rat model of acetic acid-induced gastric ulcers."3.76Enhancement of gastric ulcer healing and angiogenesis by cochinchina Momordica seed extract in rats. ( Jung, HC; Kang, JM; Kim, B; Kim, JH; Kim, JS; Kim, N; Lee, BY; Lee, HS; Lee, MK; Park, JH; Song, IS, 2010)
" This study aimed to determine the role of viable Lactobacillus in the healing of acetic acid-induced chronic gastric ulcer."3.76Yogurt containing Lactobacillus gasseri OLL 2716 (LG21 yogurt) accelerated the healing of acetic acid-induced gastric ulcer in rats. ( Kurakazu, K; Shimizu, K; Uchida, M, 2010)
" Here, we assessed whether rats infected with the tapeworm Hymenolepis diminuta were protected from gastric ulceration induced by the serosal application of acetic acid."3.75Acetic acid induced ulceration in rats is not affected by infection with Hymenolepis diminuta. ( McKay, DM; Wallace, JL, 2009)
"To evaluate the role of ALA treatment on the healing of acetic acid-induced gastric ulcer, rats were given ALA (35 mg/kg/day) or saline for 3 days before the induction of ulcer and the treatment was continued twice daily for 2 days (early) or 10 days (late) until they were decapitated."3.75Alpha-lipoic acid improves acetic acid-induced gastric ulcer healing in rats. ( Ercan, F; Erzik, C; Karakoyun, B; Yeğen, BC; Yüksel, M, 2009)
"This study is to investigate therapeutic effect of astaxanthin on acetic acid-induced gastric ulcer in rats."3.75[Therapeutic effect of astaxanthin on acetic acid-induced gastric ulcer in rats]. ( Fu, Y; Ruan, H; Yang, Q; Zhang, Z; Zhu, X, 2009)
" Optimal effective dose of PPSM (25 mg/kg) showed antiulcerogenic activity against acute gastric ulcers (GU) induced by pylorus ligation and aspirin and duodenal ulcer induced by cysteamine but not against ethanol-induced GU."3.75Effect of methanolic extract of Pongamia pinnata Linn seed on gastro-duodenal ulceration and mucosal offensive and defensive factors in rats. ( Agarwal, PK; Dorababu, M; Goel, RK; Goel, S; Joshi, VK; Prabha, T; Singh, A, 2009)
" Chronic gastric ulcers were induced in male Wistar rats by the application of 100% acetic acid to the serosal surface of the stomach on 60 sec."3.75[Influence of honey, royal jelly and propolis on accelerating acetate healing of experimental gastric ulcers in rats]. ( Belostotskiĭ, NI; Dubtsova, EA; Kas'ianenko, VI; Lazebnik, LB, 2009)
"In the present study, we compared the effects of alpha-tocopherol and probucol, antioxidants, on the healing of acetic acid-induced gastric ulcers in 8-, 48- and 96-week-old rats."3.74Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol. ( Ishihara, M; Ito, M; Kojima, R, 2008)
"A series of fenamate quinazolinyl analogues, viz acids 6a-d, esters 6e-h, carbohydrazides 7a-d, arylidenes 8a-d, oxadiazol-2-ones 13a-d and oxadiazol-2-thiones 14a-d, have been prepared and screened for their analgesic (acetic acid-induced writhing), anti-inflammatory (carrageenan-induced rat paw edema) activities as well as their ulcerogenic effects."3.74Synthesis, analgesic and anti inflammatory activities of some new fenamate analogues. ( Alafeefy, AM, 2008)
" To determine whether sequentially applied stimuli interact, we determined visceromotor responses (VMR) to gastric distension, measured at baseline and 60 min after instillation of saline, glycocholic acid (GCA) or ethanol through a gastrostomy in controls and rats with gastric ulcers."3.74Luminal stimuli acutely sensitize visceromotor responses to distension of the rat stomach. ( Bielefeldt, K; Gebhart, GF; Lamb, K, 2007)
"Gastric ulcers were induced in male rats by serosal application of acetic acid."3.74[Effect of mucosal protective on the quality of gastric ulcer healing]. ( Chen, K; Chen, SJ; Deng, YY; Liu, WL; Qian, Y; Si, JM; Sun, KK; Wang, LJ; Wu, JG; Zhu, YF, 2007)
" In the present study, we examined the effect of alendronate on the healing of acetic acid-induced gastric ulcers in rats and investigated the mechanism involved in this action both in vivo and in vitro using the rat gastric epithelial cell line (RGM1)."3.74Impairment of gastric ulcer healing by alendronate, a nitrogen-containing bisphosphonate, in rats. ( Aihara, E; Amagase, K; Hayashi, S; Nishikawa, K; Takeuchi, K, 2007)
"The effect of peroxisome proliferator-activated receptor-alpha (PPAR-alpha) on gastric secretion and gastric cytoprotection was evaluated using five different models of gastric ulcers: acetic acid-induced chronic gastric ulcers, pylorus ligation, ethanol-induced, indomethacin-induced and ischemia-reperfusion-induced gastric ulcers."3.74Effect of peroxisome proliferator-activated receptor-alpha agonist (bezafibrate) on gastric secretion and gastric cytoprotection in rats. ( Asad, M; Hrishikeshavan, HJ; Pathak, R; Prasad, S, 2007)
"Gastric ulcers were induced with acetic acid in rats; aspirin was administrated by gavage from day 25 to day 54 after ulcer induction."3.74Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007)
"Aspirin enhance the recurrence of gastric ulcer."3.74Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007)
" once daily for 1 week, markedly delayed the healing of acetic acid-induced gastric ulcers with the suppression of basic fibroblast growth factor (bFGF) expression."3.74Prophylactic effect of rebamipide against the irritative and healing impairment actions of alendronate in rat stomachs. ( Aihara, E; Amagase, K; Hayashi, S; Kato, S; Takeuchi, K, 2007)
"The healing effects on gastric ulcers inducted by subserosal injection of acetic acid were evaluated by macroscopic and microscopic measures, immunohistochemistry and cell counting in rats treated with MeOH extract of Mouriri pusa (250 mg/kg, p."3.74Studies of gastric mucosa regeneration and safety promoted by Mouriri pusa treatment in acetic acid ulcer model. ( Andreo, M; Hiruma-Lima, CA; Kushima, H; Pellizzon, CH; Takahira, RK; Vasconcelos, PC; Vilegas, W, 2008)
" Gastric ulcers were induced by serosal application of absolute acetic acid."3.74Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis. ( Ae, T; Amagase, K; Arai, K; Hattori, Y; Hayashi, I; Hosono, K; Komine, R; Kurihara, H; Kurihara, Y; Majima, M; Mizuguchi, S; Oh-Hashi, Y; Ohno, T; Okabe, S; Saeki, T; Saigenji, K; Suzuki, T, 2008)
" Acetic acid-induced gastric ulcers were produced in mice after BM transplantation."3.74Cultured bone marrow cell local implantation accelerates healing of ulcers in mice. ( Egawa, S; Hayashi, N; Iijima, H; Irie, T; Ishii, S; Kakiuchi, Y; Kawano, S; Nishida, T; Shinzaki, S; Tsuji, S; Tsujii, M; Tsutsui, S; Yasumaru, M; Yoshio, T, 2008)
" In a chronic model, by acetic acid-induced gastric ulcers, COX-2 was expressed at 7 days and was also associated with PGE(2) increase."3.73COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions. ( Alarcón de la Lastra, C; Bruseghini, L; Manuel Herrerias, J; Motilva, V; Sánchez-Fidalgo, S, 2005)
"All inflammation parameters were increased by acetic acid-induced colitis or ethanol-induced gastric ulcer compared with the control group."3.73Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes. ( Cevík, H; Ercan, F; Erkanli, G; Işman, CA; Yeğen, BC, 2005)
"The objective of the present study has been to advance knowledge of the gastric role played by the amino acid L-Arginine (L-Arg) in the evolution of a chronic gastric ulcer."3.73Administration of L-arginine reduces the delay of the healing process caused by ibuprofen. Implication of COX and growth factors expression. ( Bruseghini, L; Esteras, A; Illanes, M; Martín-Lacave, I; Motilva, V; Sánchez-Fidalgo, S, 2005)
" Since compounds with cytoprotective and antioxidant effects can improve healing of gastroduodenal ulcer induced by noxious agents, this work investigated the healing effect of D- 002 on acute and chronic gastric ulcers induced with indomethacin and acetic acid, respectively, in rats."3.73Therapeutic effect of D-002 (abexol) on gastric ulcer induced experimentally in rats. ( Arruzazabala, L; Carbajal, D; Más, R; Molina, V, 2005)
" Gaultherin, 2-[(6-O-beta-D-Xylopyranosyl-beta-D-glucopyranosyl)oxy] benzoic acid methyl ester, a natural salicylate derivative extracted from Gaultheria yunnanensis, has been shown to have analgesic and anti-inflammatory effects and lack gastric ulcerogenic effect compared to aspirin in our primary study."3.73Gaultherin, a natural salicylate derivative from Gaultheria yunnanensis: towards a better non-steroidal anti-inflammatory drug. ( Ding, Y; Du, GH; He, XL; Zhang, B, 2006)
"To assess the synergistic action of famotidine (FMD) and chlorpheniramine (CPA) on acetic acid-induced chronic gastric ulcer in rats."3.73Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats. ( Chen, C; Qin, Z, 2005)
"The synergistic action of FMD and CPA on acetic acid-induced chronic gastric ulcer in rats decreases the incidence of ulcer and also enhances the healing of ulcer."3.73Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats. ( Chen, C; Qin, Z, 2005)
"The effect of MXY to the mice's gastric ulcer induced by hydrochloric acid-ethanol, reserpine, and chronic gastric ulcer induced by acetic acid were observed."3.73[Study of the effect of exceed critical extracts from Radix Aucklandiae on experimental gastric ulcer model]. ( Han, J; Lin, H; Rong, X; Zhong, Z, 2005)
" The aim of this study was to investigate the effects of selective or non-selective inhibition of NOS on the expression and activity of COX-2 during healing of acetic acid-induced gastric ulcers in rats."3.73Differential effects of selective and non-selective inhibition of nitric oxide synthase on the expression and activity of cyclooxygenase-2 during gastric ulcer healing. ( Cho, CH; Guo, JS; Koo, MW; Wang, JY, 2006)
" Dose dependent percent inhibition of granuloma formation, exudate volume, total leukocyte count was observed in 4e (25, 50 and 100 mg/kg) and celecoxib (CAS 169590-42-5; 5 mg/kg) treated groups in the cotton pellet granuloma and granuloma pouch technique, respectively, in rats."3.73Evaluation of anti-inflammatory and analgesic activity of a new class of biphenyl analogs in animal models of inflammation. ( Bodhankar, SL; Kulkarni, VM; Rathi, BS; Wagh, NK, 2006)
" When the effect of test compound was evaluated on the 15th day after acetic acid injection to rats, repeated oral administration of tea catechin (25, 50, 100 mg/kg twice daily) dose-dependently accelerated the healing of acetic acid-induced chronic gastric ulcers."3.73Anti-ulcer effect of tea catechin in rats. ( Hamaishi, K; Ito, M; Kojima, R, 2006)
"Gastric ulcer was induced in rat by acetic acid according Okeba's method with some modification and the recurrence model was induced by IL-1beta."3.73[Effects of jianwei yuyang granule on inflammatory reaction and NF-kappaB expression in rat gastric mucosa of ulcer healing and recurrence]. ( Cao, Y; Chen, YQ; Li, JB; Ling, JH; Pan, YZ; Shen, DZ, 2006)
" Since prostaglandins are inducers of hepatocyte growth factor (HGF), we examined the effect of rebamipide on the expression of HGF, c-met, cyclooxygenase-2 (Cox-2) and subtype of the prostaglandin E2 receptor (EP2) in acetic acid-induced gastric ulcer, a model of human ulcer."3.72Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor. ( Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A, 2003)
" Gastric ulcers were produced by injecting 50 microl of 20% acetic acid into subserosa of the border between the fundic and antral gland areas."3.72Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor. ( Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A, 2003)
"To identify the pathogenesis of gastric ulcers by comparing injury to the nonglandular gastric mucosa of horses caused by hydrochloric acid (HCl) or volatile fatty acids (VFAs)."3.72Effects of hydrochloric, acetic, butyric, and propionic acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses. ( Andrews, FM; Argenzio, RA; Mathew, AG; Nadeau, JA; Patton, CS; Saxton, AM, 2003)
"Previous work demonstrates that oleanolic acid (OA), a triterpene widely distributed in plants, shows gastroprotective effect in the ethanol, aspirin and pilorous ligature-induced gastric ulcer in rats as well as in the ethanol/hydrochloric acid-induced ulcer in mice."3.72Oleanolic acid promotes healing of acetic acid-induced chronic gastric lesions in rats. ( Astudillo, L; Rodríguez, JA; Schmeda-Hirschmann, G, 2003)
"We previously discovered that a 4-wk course of indomethacin delivered to rats with acetic acid ulcers resulted in production of "unhealed gastric ulcers" that persisted for up to 12 wks after treatment cessation."3.72Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats. ( Amagase, K; Okabe, S; Tsukimi, Y; Yokota, M, 2003)
" We investigated the changes in the level of gastric colonization 140 days after inducing gastric ulcer by acetic acid in the antral mucosa of a miniature pig infected with H."3.72Temporal increase in the gastric colonization of Helicobacter pylori after healing of acetic acid-induced gastric ulcer in a miniature pig. ( Iwata, M; Katsuta, M; Kikuchi, I; Koga, T; Okazaki, Y; Sato, K; Shimada, Y; Takahashi, K, 2003)
"Effects of glucocorticoid deficiency followed by corticosterone replacement on the healing of gastric erosions and chronic gastric ulcers have been investigated in rats."3.72[Deficiency of glucocorticoid production delays the healing of acute gastric mucosal erosion and chronic ulcers in rats]. ( Bagaeva, TR; Filaretova, LP; Morozova, OIu; Podvigina, TT, 2003)
"In this study, the healing effects of Centella asiatica water extract (CE) and asiaticoside (AC), an active constituent of CE, on acetic acid induced gastric ulcers (kissing ulcers) in rats were examined."3.72The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats. ( Cheng, CL; Guo, JS; Koo, MW; Luk, J, 2004)
"Male Sprague Dawley (SD) rats were used in the following two studies: (i) the effects of risedronate and alendronate on gastric potential difference (PD), gastric mucosal blood flow (GMBF) and acid back-diffusion in the stomach mounted on ex vivo chamber under urethane anesthesia and; (ii) the influence of daily treatment with these drugs on the healing of acetic acid-induced gastric ulcers was examined."3.72Mucosal irritative and healing impairment action of risedronate in rat stomachs: comparison with alendronate. ( Aihara, E; Kanatsu, K; Kato, S; Okayama, M; Takeuchi, K, 2004)
" Conversely, the healing of acetic acid-induced gastric ulcers was significantly delayed by daily administration of these drugs, yet this effect was less pronounced in the case of risedronate."3.72Mucosal irritative and healing impairment action of risedronate in rat stomachs: comparison with alendronate. ( Aihara, E; Kanatsu, K; Kato, S; Okayama, M; Takeuchi, K, 2004)
"We used alendronate and risedronate as bisphosphonates and examined whether or not these agents have a mucosal irritative action in the stomach and impair the healing of pre-existing gastric ulcers in rats."3.72Mucosal irritative and healing impairment action of risedronate in rat stomachs: comparison with alendronate. ( Aihara, E; Kanatsu, K; Kato, S; Okayama, M; Takeuchi, K, 2004)
"Gastric ulcers were induced in normal/NIDDM rats by various physical (2 hr cold restraint stress and 4 hr pylorus ligation) and chemical agents (ethanol, 1 ml/200 g, oral, 1 hr before; aspirin, 200 mg/kg, oral, 4 hr) and duodenal ulcers were induced by cysteamine (40 mg/200 g)."3.72Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats. ( Agrawal, VK; Aryya, NC; Dorababu, M; Goel, RK; Prabha, T; Priyambada, S, 2004)
" Concerning the gastric effects, lavender oil, linalool and linalyl acetate oral administration protected against acute ethanol-induced gastric ulcers but did not prevent indomethacin-induced lesions indicating no interference with arachidonic acid metabolic cascade."3.72Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil. ( Ballabeni, V; Barocelli, E; Bianchi, A; Bruni, R; Calcina, F; Chiavarini, M; Impicciatore, M, 2004)
" lucidum on the healing of gastric ulcers induced by acetic acid in the rat and to elucidate the underlying mechanisms involved."3.72Ganoderma lucidum polysaccharide fractions accelerate healing of acetic acid-induced ulcers in rats. ( Chan, E; Gao, H; Gao, Y; Lan, J; Tang, W; Zhou, S, 2004)
"The purpose of this study was to evaluate the healing effect of interleukin-11 (IL-11) on acetic acid-induced gastric ulcer in rats."3.71Mechanism of the antiulcerogenic effect of IL-11 on acetic acid-induced gastric ulcer in rats. ( Fukuda, E; Ito, M; Matsuu, M; Nakashima, M; Nakayama, T; Sekine, I; Shichijo, K; Wen, CY, 2002)
"Acetic acid was perfused into the gastric cavitties of 130 rats to produce animal model of /gastric ulcer."3.71[Expression and activity of cyclooxygenases-1 and -2 in acetic acid induced gastric ulcer in rats]. ( Guo, J; Koo, MW; Wang, J, 2001)
"Acetic acid-induced gastric ulcers were prepared in 8-week-old male Wistar rats."3.71Expression of a specific mucin type recognized by monoclonal antibodies in the rat gastric mucosa regenerating from acetic acid-induced ulcer. ( Hayashida, H; Hotta, K; Ichikawa, T; Ishihara, K; Kurihara, M; Okayasu, I; Saigenji, K, 2001)
"Proteoglycan expression was studied by immunohistochemistry and in situ hybridization in acetic acid-induced gastric ulcers in rat during early phases and during chronic ulceration."3.71Expression of decorin and biglycan in rat gastric tissue: effects of ulceration and basic fibroblast growth factor. ( Altenburger, M; Domschke, W; Konturek, JW; Kresse, H; Pohle, T; Shahin, M, 2001)
" The acute gastric ulcer models used were pylorus ligation, indomethacin-induced and ethanol-induced gastric ulcers."3.71Effect of centrally administered prolactin on gastric and duodenal ulcers in rats. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001)
"Expression of MIF was examined in a rat gastric ulcer model induced by acetic acid, and the functional role of MIF in acute gastric ulcer was investigated by administration of a neutralizing anti-MIF antibody."3.71Macrophage migration inhibitory factor is an important mediator in the pathogenesis of gastric inflammation in rats. ( Bucala, R; Chen, YX; Cho, CH; Chun Hui, CW; Chun, B; Fung, PC; Huang, XR; Hui, WM; Lam, SK; Lan, HY; Metz, C; Wong, BC; Wong, Y, 2001)
"To investigate the effect of Jianpiyiqi prescription on the expression of heat shock proteins (HSPs) and the changes of HSPs in gastric-ulcerated rats, the rat model of chronic gastric ulcer was induced by acetic acid."3.71Effect of jianpiyiqi prescription on the expression of heat shock proteins in acetic acid-induced chronic gastric ulcer rats. ( Li, G; Luo, S; Tao, X, 2001)
" The acute gastric ulcer models used were pylorus ligation, indomethacin, ethanol and histamine induced acute gastric ulcers."3.71Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001)
"9), when given in the dose of 10-50 mg/kg, twice daily for 5 days, showed dose-dependent anti-ulcerogenic on various gastric ulcer models induced by ethanol, aspirin, 2 h cold restraint stress and 4 h pylorus ligation."3.71Prophylactic and curative effects of Bacopa monniera in gastric ulcer models. ( Babu, MD; Goel, RK; Rao, CV; Sairam, K, 2001)
"ethanol-induced gastric lesion, aspirin-induced gastric ulcer, acetic acid-induced ulcer and Shay ulcer."3.71Effect of butanol fraction of Panax ginseng head on gastric lesion and ulcer. ( Jeong, CS, 2002)
"To investigate the possible role of cyclooxygenase-2 (COX-2) inhibitor NS-398 in formation and healing of acetic acid-induced gastric ulcer in rats."3.71[Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001)
"Fourty eight male Sprague-Dawley rats weighed 160-180 g were perfused with acetic acid into the stomach to induce gastric ulcer and then divided into two groups."3.71[Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001)
"NS-398 inhibits COX-2 activity, thus alleviating inflammatory reaction in acetic acid induced gastric ulcer and averting further damage of tissues."3.71[Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001)
" In the second set of experiments, acetic acid-induced gastric ulcers were examined."3.71Transient increase of rat gastric amylin in the neonatal period and in experimental ulcers. ( Karlsson, FA; Li, Z; Shi, A, 2002)
" pylori infection, indomethacin, and their combination affects the healing of gastric ulcers and whether or not such factors provoke a relapse of healed gastric ulcers in Mongolian gerbils."3.71Influence of Helicobacter pylori infection on healing and relapse of acetic acid ulcers in Mongolian gerbils. ( Ebata, M; Keto, Y; Okabe, S; Tomita, K, 2002)
" A mechanistic study of the potentiating effects of cigarette smoking on acetic acid-induced gastric ulceration in rats was hence performed."3.70Mechanistic study of adverse actions of cigarette smoke exposure on acetic acid-induced gastric ulceration in rats. ( Cho, CH; Chow, JY; Ma, L, 1998)
"Based on our previous studies that aspirin (ASA) -induced gastric ulceration in rats can be significantly reduced if the drug is chemically associated with phosphatidylcholine (PC), we undertook the present study to compare gastric ulcer healing rates in rats administered either unmodified or PC-complexed ASA."3.70Phosphatidylcholine-associated aspirin accelerates healing of gastric ulcers in rats. ( Kurinets, A; Lichtenberger, LM, 1998)
"Effect of lafutidine ((+/-)-2-(furfurylsulfinyl)-N-[4-[4-(piperidinomethyl)-2-pyr idyl] oxy-(Z)-2-butenyl] acetamide, FRG-8813), a novel antiulcer agent, on the healing and relapse in acetic acid-induced gastric ulcer in rats was investigated."3.70[Effect of lafutidine, a novel antiulcer agent, on healing and relapse of acetic acid-induced gastric ulcer in rats]. ( Aoyama, M; Arai, Y; Ohnishi, H; Onodera, S; Shibata, M; Tanaka, M; Yamaura, T, 1998)
" In this study, we examined whether this antichemotactic factor as well as chemotactic factors are involved in the indomethacin-induced delayed healing of experimental gastric ulcers."3.70Mechanism by which indomethacin delays the healing of acetic acid-induced ulcers in rats. Role of neutrophil antichemotactic and chemotactic activities. ( Fujita, H; Okabe, S; Takahashi, S, 1998)
" Gastric ulcers were induced by serosal application of acetic acid."3.70Bacteria rapidly colonize and modulate healing of gastric ulcers in rats. ( Buret, A; Elliott, SN; McKnight, W; Miller, MJ; Wallace, JL, 1998)
"We investigated the effect of probucol, a lipid-lowering agent with antioxidant properties, on HCl plus ethanol-induced gastric mucosal injury and on the healing of acetic acid-induced gastric ulcers in rats."3.70Anti-ulcer effects of antioxidants: effect of probucol. ( Ishihara, M; Ito, M; Suzuki, Y, 1998)
" at an effective anti-inflammatory dose to rats with pre-existing acetic acid-induced gastric ulcer, NS-398 caused a statistically significant delay of ulcer healing."3.70Effects of novel anti-inflammatory compounds on healing of acetic acid-induced gastric ulcer in rats. ( Dyer, RD; Gilbertsen, RB; Guglietta, A; Kraus, ER; Lesch, CA; Sanchez, B; Schrier, D; Song, Y, 1998)
"To investigate whether or not heparin can accelerate the healing process of acetic acid-induced gastric ulcers in rats and to identify the mechanisms for heparin to produce this effect, so that we can develop a new therapeutic application to heparin besides its traditional anticoagulant activity."3.70Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998)
"Male Sprague-Dawley rats were used to produce acetic acid-induced gastric ulcers."3.70Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998)
"Heparin with the doses used in the present study accelerated the healing of acetic acid-induced gastric ulcers in rats in a dose- and time-dependent manner, and this action was related to its effects to increase the levels of gastric mucosal PGE2 and GMBF as well as to decrease the gastric mucosal MPO activity."3.70Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998)
"The healing of experimental gastric ulcers induced in rats is consistently delayed upon chronic treatment with indomethacin."3.70A new ulcer model, "unhealed gastric ulcers", induced by chronic treatment with indomethacin in rats with acetic acid ulcers. ( Amagase, K; Okabe, S, 1999)
"We investigated the role of endogenous interleukin (IL)-1 in the mRNA expression of cyclooxygenase (COX)-1, COX-2, inducible nitric oxide synthase (iNOS), cytokine-induced neutrophil chemoattractant (CINC)-1, epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), hepatocyte growth factor (HGF), and transforming growth factor (TGF)-beta1 in acetic acid-induced gastric ulcers in rats."3.70Regulation by endogenous interleukin-1 of mRNA expression of healing-related factors in gastric ulcers in rats. ( Kobayashi, N; Okabe, S; Takahashi, S, 1999)
" The pharmacokinetics of the drug were also evaluated after oral administration to rats with acetic acid-induced gastric ulcer (AIURs)."3.70Gastrointestinal absorption of a new reversible proton pump inhibitor, YJA-20379-8, and its pharmacokinetics after oral administration in acetic acid-induced gastric ulcer in rats. ( Chang, MS; Chung, SY; Han, KS; Kim, HJ; Kim, J; Lee, MG, 1999)
" pylori infection in an acetic acid-induced gastric ulcer (AAU) model in Mongolian gerbils."3.70Distribution of Helicobacter pylori in a Mongolian gerbil gastric ulcer model. ( Akashi, T; Isobe, Y; Kaneda, Y; Kijima, H; Kimura, M; Miyata, H; Yagi, K, 1999)
"Pylorus ligated, water immersion stress-induced, reserpine-induced, and acetic acid-induced gastric ulcers in rats or mice were prepared."3.70Effect of recombinant human basic fibroblast growth factor on stomach ulcers in rats and mice. ( Gao, MT; Li, WG; Rao, CM; Wang, JZ; Wu, YJ, 1999)
"In acetic acid-induced gastric ulcers in rats, rh-bFGF 2."3.70Effect of recombinant human basic fibroblast growth factor on stomach ulcers in rats and mice. ( Gao, MT; Li, WG; Rao, CM; Wang, JZ; Wu, YJ, 1999)
" In this study, we examined the effect of pentoxifylline on healing of acetic acid induced gastric ulcers in rats."3.70Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000)
"Pentoxifylline accelerates healing of acetic acid induced gastric ulcer in rats."3.70Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000)
"Rats with gastric ulcer received an intraperitoneal injection of 10 mg/kg pentoxifylline once daily for 14 days or for only the first 7 days or the last 7 days of the 14-day treatment period."3.70Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000)
"To investigate the influence of water extracts of CagA-positive or -negative Helicobacter pylori on healing of chronic gastric ulcers and on connexin formation, proliferation and apoptosis, in acetic acid-induced chronic gastric ulcers in rats."3.70The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000)
"Acetic acid was used to induce chronic gastric ulcers in rats, and a water extract of H."3.70The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000)
"In untreated rats, acetic acid-induced gastric ulcers healed after 14 days and the electrophoretic band corresponding to connexin 32 appeared 4 days after ulcer induction."3.70The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000)
" Furthermore, acetic acid ulcer, which is a model of chronic gastric ulcer, was experimentally induced in the stomachs of rats to assess the influence of 0."3.69Influence of ammonia solution on gastric mucosa and acetic acid induced ulcer in rats. ( Fujiki, N; Hata, M; Kato, T; Kohli, Y; Ueda, T; Yamazaki, Y, 1994)
"Effects of treatment with free radical scavengers in the healing process of acetic acid-induced gastric ulcer on the ulcer aggravation induced by indomethacin were investigated."3.69Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats. ( Kondo, M; Matsuyama, K; Naito, Y; Nishimura, S; Yagi, N; Yoshikawa, T, 1995)
"This study was done to elucidate whether rebamipide during the initial period of acetic acid-induced gastric ulcer affected healing and future ulcer relapse."3.69Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine. ( Arakawa, T; Fukuda, T; Kobayashi, K; Watanabe, T; Yamasaki, K, 1995)
"Tobacco cigarette smoke attenuates injury-induced hyperemia, aggravates hypertonic saline-induced mucosal damage, inhibits ulcer margin hyperemia, and increases the size of the acetic acid-induced ulcer in the rat stomach."3.69Misoprostol reverses the inhibition of gastric hyperemia and aggravation of gastric damage by tobacco cigarette smoke in the rat. ( Iwata, F; Leung, FW, 1995)
"The healing of acetic acid-induced gastric ulcer in rats and the effects of cimetidine and calcitonin were investigated with reference to the enzyme activity of both prolylhydroxylase and collagenase as related to histological findings."3.69Wound healing of acetic acid-induced gastric ulcer in rats and the effects of cimetidine and calcitonin, with special reference to prolylhydroxylase and collagenase enzyme activity. ( Arai, M; Komatsu, H; Kurose, I; Maruyama, K; Nakamura, M; Okazaki, I; Tsuchiya, M, 1995)
"We determined the kinetics and phenotypes of infiltrating B cells in gastric ulcer in the rat induced by gastric injection of acetic acid (day 0)."3.69Two phenotypically distinct B lymphocytes (IgMhighIgDlow and IgMlowIgDhigh) in chronic gastric ulcer in the rat. ( Arisawa, T; Asai, J; Goto, H; Hayakawa, T; Ito, M; Ohbayashi, M; Ohmiya, N; Tsukamoto, Y, 1995)
"The effects of IGN-2098 on the healing process of acetic acid-induced gastric ulcer was investigated in comparison with the other histamine H2-receptor antagonists, famotidine and roxatidine acetate HCl, in rats."3.69[Therapeutic effect of IGN-2098, a new antiulcer drug (H2-antagonist), in the ulcer diminishing period against acetic acid-induced gastric ulcer in rats]. ( Ikarashi, Y; Misaki, N; Ohba, S; Ohbayashi, S; Uchida, M, 1995)
"We examined the effect of a liquid diet or a combined diet of liquid plus cellulose on the healing of gastric ulcers induced in rats in comparison with that of solid chow."3.69Acceleration of healing of gastric ulcers induced in rats by liquid diet: importance of tissue contraction. ( Okabe, S; Tsukimi, Y, 1994)
" Eto inhibited carrageenin-induced edema in rats, adjuvant-induced arthritis in rats, acetic acid-induced writhing in mice and brewer's yeast-induced hyperalgesia and fever in rats."3.69Anti-inflammatory effects of etodolac: comparison with other non-steroidal anti-inflammatory drugs. ( Fujisawa, H; Inoue, K; Inoue, Y; Kimura, K; Kyoi, T; Motonaga, A; Ueda, F, 1994)
"We tested the hypothesis that attenuation of the hyperemia at the margin of acetic acid-induced gastric ulcer in rats by tobacco cigarette smoke will increase the size of the ulcer in the acute and the healing stages."3.69Tobacco cigarette smoke aggravates gastric ulcer in rats by attenuation of ulcer margin hyperemia. ( Iwata, F; Leung, FW, 1995)
"The effects of cimetidine, omeprazole and atropine sulfate on the healing of acetic acid-induced gastric ulcers in rats with limited food intake time (9:00-10:00 a."3.69Effect of cimetidine and omeprazole on gastric ulcer healing of rats with limited food intake time. ( Ito, M; Kojima, R; Segami, T; Suzuki, Y; Tsukahara, T, 1994)
" Gastric ulcers were induced by application of acetic acid using a standard technique."3.69Effects of misoprostol on delayed ulcer healing induced by aspirin. ( Andrews, FJ; O'Brien, PE; Penney, AG, 1994)
"Gastric ulcers were induced in rats by acetic acid treatment, and the mast cell kinetics in the lesions were studied."3.69Increase in mucosal and connective tissue-type mast cells in the stomach with acetic acid-induced ulcer in rat. ( Arizono, N; Bamba, T; Hattori, T; Nakajima, S, 1996)
" Gastric ulcers were induced in young, adult, and aged rats using serosal or mucosal (kissing ulcers) application of acetic acid."3.69Influence of age on natural and delayed healing of experimentally-induced gastric ulcers in rats. ( Andrews, FJ; O'Brien, PE; Penney, AG, 1996)
"We investigated the effects of cimetidine, omeprazole and atropine, antisecretory anti-ulcer agents, on the healing of gastric and duodenal ulcers simultaneously induced in the same rats."3.69Simultaneous evaluation of gastric and duodenal ulcers-healing activities of anti-ulcer agents in rats. ( Ito, M; Segami, T; Suzuki, Y, 1996)
"To investigate the effect of capsaicin, cimetidine, and in combination, given intragastrically in the healing of acetic acid induced chronic gastric ulcer in the rat."3.69Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996)
"Capsaicin promotes the healing of acetic acid induced gastric ulcer, probably by its gastric hyperaemic effect."3.69Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996)
"Capsaicin protects the gastric mucosa against experimental injury while capsaicin desensitisation reduces the rate of gastric ulcer healing."3.69Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996)
"To clarify the relationship between Helicobacter pylori and the healing of gastric ulcers, we investigated the healing of acetic acid-induced gastric ulcers in the antral mucosa of Japanese monkeys (n = 5) infected with H."3.69Helicobacter pylori infection delays the healing of acetic acid-induced gastric ulcer in Japanese monkeys. ( Fujioka, T; Kodama, R; Kubota, T; Nasu, M; Shuto, R, 1996)
"We found indomethacin aggravates healed gastric ulcers (ulcer relapse) in rats."3.69Prevention of gastric ulcer relapse induced by indomethacin in rats by a mutein of basic fibroblast growth factor. ( Asano, S; Inada, I; Maeda, R; Murakami, I; Sato, F; Satoh, H; Shino, A, 1997)
" Therefore, the aim of this study was to examine the role of collagenase and gelatinases A and B in the development and healing of acetic acid-induced gastric ulcer in rats."3.69Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997)
"Gastric ulcer was induced by injecting 20 microliters glacial acetic acid into gastric wall of rat stomachs."3.69Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997)
"The aim of this study was to examine the synthesis of sulfated glycosaminoglycans during normal healing of experimental acetic acid-induced gastric ulcer in rats and to investigate the effect of indomethacin, a drug known to delay ulcer healing, on this synthesis using an in vivo labelling system."3.69Changes in sulfated macromolecules produced in vivo during normal and indomethacin-delayed ulcer healing in rats. ( Andrews, FJ; Comper, WD; Lyons, KC; O'Brien, PE, 1997)
" Northern blot analysis revealed that PGC gene expression was enhanced not only in acetic acid-induced chronic gastric ulcers but also in indomethacin-induced gastric mucosal lesions."3.69Pepsinogen C gene product is a possible growth factor during gastric mucosal healing. ( Chiba, T; Kawanami, C; Kinoshita, Y; Kishi, K; Maekawa, T; Matsushima, Y; Okada, A; Watanabe, N, 1997)
"Procollagens alpha 1 (I), alpha 1 (III), and alpha 1 (IV) RNA and their polypeptides were assessed in acetic acid induced rat gastric ulcers by in situ hybridisation and immunohistochemistry."3.69Gastric ulcer healing in the rat: kinetics and localisation of de novo procollagen synthesis. ( Domschke, W; Gillessen, A; Herbst, H; Pohle, T; Schuppan, D; Shahin, M; Weber, C, 1997)
"Immunohistological staining was done using the antibodies for the proliferating cell nuclear antigen prolyl 4-hydroxylase and alpha-smooth muscle actin in acetic acid induced gastric ulcers in rats."3.69Kinetics of fibroblasts in ulcer healing in rats: interference with indomethacin. ( Arisawa, T; Asai, J; Goto, H; Hase, S; Hayakawa, T; Hirose, Y; Niwa, Y; Tsukamoto, Y, 1997)
"This study examined the relationship between healing of acetic acid-induced chronic gastric ulcer and connexin formation."3.69Relationship between healing of acetic acid-induced chronic gastric ulcer and connexin. ( Fujita, T; Kushima, R; Mine, T, 1997)
"We investigated the influence of inhibition of nitric oxide (NO) synthase, using NG-nitro-L-arginine (L-NNA) or NG-mono-methyl-L-arginine (L-NMMA), and the effects of exogenous donor of NO, such as glyceryl trinitrate (GTN), on the healing of chronic gastric ulcers induced by acetic acid, on gastric blood flow around the ulcer and on the number of capillaries in the granulation tissue at the ulcer bed."3.68Inhibition of nitric oxide synthase delays healing of chronic gastric ulcers. ( Brzozowski, T; Konturek, SJ; Majka, J; Pytko-Polonczyk, J; Stachura, J, 1993)
" We investigated proliferative activity in the healing process of acetic acid-induced gastric ulcer by immunohistochemical staining of PCNA and 5-bromo-2-deoxyuridine (BrdU), and the two methods were compared."3.68Cell proliferation kinetics in acetic acid-induced gastric ulcer evaluated by immunohistochemical staining of proliferating cell nuclear antigen. ( Hiramatsu, A; Inoue, K; Kitajima, T; Mizuno, T; Nakano, T; Okuhira, M; Tani, K, 1993)
" The antiulcer activity of vinpocetine was demonstrated also in gastric injury induced by phenylbulazone and in chronic gastric ulcer induced by acetic acid."3.68Protective action of vinpocetine against experimentally induced gastric damage in rats. ( Babulová, A; Machová, J; Nosálová, V, 1993)
"Effects of troxipide (Ku-54) on various experimental gastric ulcers in rats were studied."3.68[The pharmacodynamics of troxipide on experimental gastric ulcers in rats]. ( Fan, A; Fang, Z; Wang, J; Wang, Y; Zhang, L, 1993)
"To clarify the ability of endoscopic ultrasonography (EUS) to diagnose gastric ulcer, we induced gastric ulcer (19 open ulcers and 11 ulcer scars) by injecting acetic acid into the stomach via an endoscope in 15 dogs."3.68Evaluation of acetic acid-induced gastric ulcers in dogs by endoscopic ultrasonography. ( Chijiiwa, Y; Fujishima, H; Maruoka, A; Misawa, T; Nawata, H, 1993)
"We examined the effect of NC-1300-O-3 on the healing of acetic acid-induced gastric ulcers in male Donryu rats."3.68Effect of NC-1300-O-3 on healing of acetic acid-induced gastric ulcers in rats. ( Inoue, K; Okabe, S; Takagi, K, 1993)
" Administration of bFGF (3-300 micrograms/kg/day) by an intragastric or an intraperitoneal route or sucralfate (400 mg/kg/day) orally to rats with acetic acid induced gastric ulcers, enhanced the healing rate of these ulcers during seven day treatment in a dose dependent manner."3.68Fibroblast growth factor in gastroprotection and ulcer healing: interaction with sucralfate. ( Bielanski, W; Brzozowski, T; Konturek, SJ; Majka, J; Otto, W; Stachura, J; Szlachcic, A, 1993)
"Repeated administration of indomethacin delays the healing of acetic acid-induced gastric ulcers in rats, but the underlying mechanism remains unclear."3.68Mechanism by which indomethacin delays gastric ulcer healing in the rat: inhibited contraction of the ulcer base. ( Ogihara, Y; Okabe, S, 1993)
"Repeated administration of indomethacin or prednisolone for 2 weeks apparently delayed the healing of initial gastric ulcers induced by acetic acid injection in rats."3.68Effects of indomethacin and prednisolone on the different stages of healing of acetic acid-induced gastric ulcers in the rat. ( Ogihara, Y; Okabe, S, 1993)
"The effect of a proton pump inhibitor, omeprazole (OPZ), in combination with mouse epidermal growth factor (EGF), on the healing of chronic gastric ulcers induced by acetic acid in submandibular glands removed rats (SMR rat) was investigated."3.68[Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats]. ( Imai, S; Itoh, M; Joh, T; Takeuchi, T; Yokoyama, Y, 1992)
" When administered twice daily at various doses (1-100 mg/kg) for 10 days, ebrotidine reduced dose dependently the area of chronic gastric ulcers, and it was accompanied by significantly higher contents of epidermal growth factor (EGF) in the ulcer bed than in the intact mucosa."3.68Gastroprotective and ulcer-healing activities of a new H2-receptor antagonist: ebrotidine. ( Brzozowski, T; Konturek, SJ; Majka, J, 1992)
" Two experimental gastric ulcer models were selected: chronic acetic acid-induced ulcers and cold stress-induced ulcers."3.68[The antigastroulcerative activity of beta-sitosterol-beta-D-glucoside and its aglycone in rats]. ( Jiu, M; Xiao, M; Xiao, R; Yang, Z; You, J, 1992)
"The localization of fibronectin (FN) and laminin (LM) and cellular kinetics of epithelium in acetic acid induced gastric ulcers were examined by immunohistochemistry, comparing fundic glands ulcer with fundic-pyloric border ulcer."3.68[The immunohistochemical study on the recurrent mechanism of acetic acid induced gastric ulcer in rats--extracellular matrix and cellular kinetics]. ( Yagi, K, 1992)
"To investigate the destructive process of connective tissues in gastric ulcer, both collagenolytic and gelatinolytic activities were examined in the homogenates of rat acetic acid-induced gastric ulcer, a typical model of chronic ulcer."3.68Effects of H2-receptor antagonists on matrix metalloproteinases in rat gastric tissues with acetic acid-induced ulcer. ( Ito, A; Kakizaki, M; Mori, Y; Murakami, S; Nagase, H; Yamada, H, 1991)
"We investigated the effects of cimetidine and omeprazole on angiogenesis in granulation tissue and on the healing of gastric ulcers induced by acetic acid in rats."3.68Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats. ( Goto, H; Hase, S; Segawa, K; Tsuchida, T; Tsukamoto, Y, 1990)
"To clarify the mechanism of gastric ulcer recurrence, we studied acetic acid-induced gastric ulcers."3.68Evaluation of acetic acid-induced gastric ulcers in rats by scanning acoustic microscopy. ( Goto, H; Hase, S; Mizutani, K; Niwa, Y; Ohashi, S; Tsukamoto, Y, 1991)
"The macroscopic and microscopic effects of 12-sulfodehydroabietic acid monosodium salt (TA-2711, CAS 86408-72-2) on the healing of acetic acid-induced gastric ulcers in rats were compared with those of sucralfate and carbenoxolone."3.68Effects of the new anti-ulcer agent 12-sulfodehydroabietic acid monosodium salt on healing of acetic acid-induced gastric ulcers in rats. ( Iwasaki, H; Magaribuchi, T; Onoda, Y; Tamaki, H, 1991)
"Repeated administration of indomethacin markedly delays spontaneous healing of experimental gastric ulcers induced in rats."3.68Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats. ( Hirose, H; Okabe, S; Takeuchi, K, 1991)
"The present study was designed to investigate the changes in gastric mucosal PGI2 level accompanying the healing of acetic acid-induced gastric ulcers in rats."3.68Healing of acetic acid-induced gastric ulcer and gastric mucosal PGI2 level in rats. ( Irino, O; Kawano, O; Misaki, N; Saitoh, K; Uchida, M, 1990)
"The present study was designed to assess histologic and ultrastructural features of gastric mucosa in the areas of grossly healed ulcers (acetic acid-induced gastric ulcers) in rats."3.68"Healed" experimental gastric ulcers remain histologically and ultrastructurally abnormal. ( Dabros, W; Gergely, H; Hollander, D; Krause, WJ; Stachura, J; Tarnawski, A, 1990)
"The present study examined the time sequence and histologic and ultrastructural features of the formation and evolution of experimental, acetic acid-induced gastric ulcerations in rats."3.68Vascular and microvascular changes--key factors in the development of acetic acid-induced gastric ulcers in rats. ( Dabros, W; Eltorai, M; Gergely, H; Hollander, D; Krause, WJ; Stachura, J; Tarnawski, A, 1990)
"Epidermal growth factor (EGF) has been shown to enhance healing of experimental gastric ulcers when given subcutaneously or orally in the drinking water."3.68Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat. ( Endoh, K; Imai, S; Itoh, M; Iwai, A; Joh, T; Kawai, T; Matsusako, K; Takeuchi, T; Yasue, N; Yokoyama, Y, 1990)
"Omeprazole, a gastric mucosal proton pump inhibitor, significantly and dose-dependently prevented the delayed healing of acetic acid-induced gastric ulcers in response to repeatedly administered indomethacin to rats."3.68Effect of omeprazole on delayed healing of acetic acid-induced gastric ulcers in rats. ( Nagai, H; Okabe, S; Wang, JY, 1990)
"Combined treatment with the H2 antagonist ranitidine and the cytoprotective agent pentacaine was studied in acute gastric lesions induced by phenylbutazone and stress, in chronic gastric ulcers induced by acetic acid, and in Shay's model of gastric secretion stimulated by histamine."3.68Efficacy of combined ranitidine and pentacaine treatment in experimentally induced gastric damage in rats. ( Babul'ová, A; Benes, L; Nosál'ová, V, 1990)
"The anti-ulcer effect of sofalcone, an isoprenyl chalcone derivative, on acetic acid-induced gastric ulcers in rats was studied histologically and histochemically."3.67Effect of 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy) chalcone (sofalcone) on chronic gastric ulcers in rats. ( Arai, I; Kimura, M; Nakane, S; Saziki, R; Tarumoto, Y, 1984)
"The effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on various experimental gastric ulcers and gastric secretion in experimental animals was compared with that of cimetidine and cetraxate."3.67Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals. ( Aratani, S; Enomoto, H; Kimura, K; Mimura, K; Nomura, A; Ueda, F, 1984)
"The progress of acetic acid-induced gastric ulcers in rats were sequentially observed with an endoscope for 365 days, and the influences of the ulcer-induced site, age and sex on the healing, recurrence and relapse of these ulcers were investigated."3.67[Experimental studies on gastric ulcer (6). Endoscopical evaluation of healing processes of acetic acid ulcer in rats (2): Healing, recurrence and relapse of ulcer]. ( Fukawa, K; Irino, O; Kawano, O; Misaki, N; Uchida, M, 1984)
"In an attempt to elucidate the role of granulation vessels in the healing of gastric ulcer, healing and angiogenesis in granulation tissue of acetic acid ulcers were studied in rats."3.67Effects of prednisolone and human epidermal growth factor on angiogenesis in granulation tissue of gastric ulcer induced by acetic acid. ( Hase, S; Nakazawa, S; Segawa, K; Tsukamoto, Y, 1989)
"The present study was undertaken to elucidate the role of mucous secreting cells in the healing of acetic acid-induced gastric ulcers in rats."3.67Physiological significance of mucous neck cell-type mucins in the healing of acetic acid-induced gastric ulcers in rats. ( Hashikura, Y; Ichikawa, H; Katsuyama, T; Kobayashi, C; Sugiyama, A, 1989)
"We examined the changes in prolylhydroxylase (PH) and interstitial collagenase (CA) activities in the healing of acetic acid-induced gastric ulcers in rats."3.67Prolylhydroxylase and collagenase activities in the healing of acetic acid-induced gastric ulcers in rats and the effects of cimetidine and elcatonin. ( Komatsu, K; Kurose, I; Maruyama, K; Oda, M; Okazaki, I; Tsuchiya, M, 1989)
"We investigated the roles of endogenous leukotrienes (LTs) and prostaglandins (PGs) in the healing of gastric ulcers induced by acetic acid in rats."3.67Roles of endogenous leukotrienes and prostaglandins in the healing of gastric ulcers induced by acetic acid in rats. ( Arakawa, T; Fukuda, T; Kobayashi, K; Nakamura, H; Nebiki, H; Torii, Y, 1989)
"Changes in the pH gradient and thickness of the mucus gel layer in the healing of acetic acid-induced gastric ulcers in rats were investigated."3.67Role of the mucus gel layer in the healing of acetic acid-induced gastric ulcers in rats. ( Kawano, O; Matsueda, K; Misaki, N; Muraoka, A; Uchida, M; Umeda, N, 1989)
"We examined the effect of human epidermal growth factor (hEGF) on the healing rate of gastric ulcers induced in rats."3.67Effects of human epidermal growth factor on natural and delayed healing of acetic acid-induced gastric ulcers in rats. ( Kuwahara, Y; Okabe, S, 1989)
"We examined the mechanism by which repeated administration of indomethacin significantly delays the natural healing of experimental gastric ulcers induced in rats."3.67Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin. ( Okabe, S; Takeuchi, K; Wang, JY; Yamasaki, S, 1989)
"A metalloproteinase was extracted from a medium of cultured gastric tissues following acetic acid-induced ulcer or taurocholic acid-induced gastritis, and the enzyme was partially purified by Sephadex G-200 column chromatography."3.67Production of metalloproteinase in gastric tissue with acetic acid-induced ulcer or taurocholic acid-induced gastritis. ( Ishikura, Y; Mori, Y; Murakami, S; Nakanishi, J; Tsuchiya, S, 1987)
" Arbaprostil, given orally in doses of 1-100 micrograms/kg twice daily for 2 weeks, had little or no effect on the healing of acetic acid-induced gastric ulcers."3.67Effects of 15(R)-15-methyl prostaglandin E2 (arbaprostil) on gastric secretion and various gastric lesions induced in rats. ( Jino, H; Nishida, A; Okabe, S, 1986)
"Chronic gastric ulcers were produced by injection of 20% acetic acid (0."3.67Effects of trimoprostil on healing and recurrence of acetic acid-induced gastric ulcer in rats. ( Nakamura, K; Umeda, Y, 1986)
" prevented formation of ulcers induced by serotonin, indomethacin, acetylsalicylic acid or stress (acute ulcer models), its effect being greater against gastric ulcers induced by serotonin."3.67Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103). ( Hoshina, K; Naruchi, T; Takeshita, T; Yamazaki, N, 1985)
"Changes in the incorporation of 3H-glucosamine into the macromolecular glycoprotein during the healing process of acetic acid induced gastric ulcer in rats were sequentially examined in the ulcer region and the intact region at 2, 10, 40, 80 and 365 days after the operation."3.67[Changes in the biosynthetic activity of gastric glycoproteins during the healing process of acetic acid ulcer in rats]. ( Ishikura, Y; Mori, Y; Murakami, S, 1985)
") inhibited the development of gastric ulcers induced by pylorus ligation, water-immersion stress, aspirin and reserpine and duodenal ulcers induced by cysteamine in rats."3.67Effect of elcatonin on experimental gastric and duodenal ulcers. ( Noguchi, M; Ohno, H; Takayanagi, N, 1985)
" Oral or intraduodenal administration of AG 629 in a dose range of 25-100 mg/kg inhibited water-immersion stress ulcer, exertion ulcer, Shay ulcer, indometacin- and acetylsalicylic acid (ASA)-induced gastric ulcer, and indomethacin-induced small intestinal ulcer in rats, histamine-induced gastric ulcer in guinea pigs, and ASA-induced gastric ulcer in dogs, though it was not effective against cysteamine-induced duodenal ulcer in rats."3.67Effects of 5-acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one, a new anti-ulcer agent, on experimental acute and chronic ulcers. ( Hirata, T; Inada, I; Inatomi, N; Maki, Y; Satoh, H; Sino, A, 1985)
" Finally, absorption, distribution, metabolism, and excretion (ADME) was used to evaluate the bioavailability of potential compounds."1.72The effect of anti-alcoholic gastric ulcer before and after vinegar-processed Yuanhu Zhitong prescription based on spectral-effect relationship. ( Dong, J; Hou, A; Jiang, H; Kuang, H; Lv, J; Wang, S; Wang, X; Yang, L; Yu, H; Zhang, J; Zhang, S; Zheng, S, 2022)
"Gastric ulcers were induced by submucosal injections of 40% acetic acid solution into stomach submucosa and bilateral inferior vagal ganglia were collected one week afterwards."1.56Inferior vagal ganglion galaninergic response to gastric ulcers. ( Franke-Radowiecka, A; Juranek, J; Kaleczyc, J; Mogielnicka-Brzozowska, M; Pidsudko, Z; Zalecki, M, 2020)
"The treatment with hesperidin at 3 and 10 mg/kg, once a day, by seven days, accelerated by 34 and 62%, respectively, the ulcer healing process when compared to vehicle-treated group (99."1.51Hesperidin, a citrus flavanone glycoside, accelerates the gastric healing process of acetic acid-induced ulcer in rats. ( Boeing, T; Bolda Mariano, LN; Cechinel-Filho, V; da Silva, LM; de Andrade, SF; de Souza, P; Dos Santos, AC; Longo, B; Mariott, M; Pezzini, BC; Somensi, LB, 2019)
"Gastric ulcer is one of the main prevalent gastrointestinal multi-etiological disorders with many associated complications and adverse effects."1.51Antiulcer activity of Cyperus alternifolius in relation to its UPLC-MS metabolite fingerprint: A mechanistic study. ( Abdallah, HMI; Efferth, T; Elshamy, AI; Farag, MA; Farrag, ARH; Gendy, AEGE; Hegazy, MF; Khattab, AR; Mohamed, TA, 2019)
" Dose-response curves were generated for tapentadol, diclofenac, and their combination in the acetic acid-induced writhing test in mice."1.48Assessment of the antinociceptive and ulcerogenic activity of the tapentadol-diclofenac combination in rodents. ( Alonso-Castro, ÁJ; Granados-Soto, V; Isiordia-Espinoza, MA; Sánchez-Enriquez, S; Zapata-Morales, JR, 2018)
"Acetic acid ulcers were induced either in the region between the fundus and pylorus on the anterior wall of the stomach or in the glandular region on the greater curvature of the stomach to determine whether there were regional differences in the effect of the ulcers."1.46Gastric emptying after artificial ulceration in rats: differences due to the site of the ulcer and the effects of prokinetic drugs. ( Kobayashi, O; Shimizu, K; Uchida, M, 2017)
"Ulcers were induced by serosal application of 80 % acetic acid to the stomach of rats anaesthetized with 50 mg/kg thiopentone sodium and treatment was given three times daily."1.46Effects of quinine on gastric ulcer healing in Wistar rats. ( Adeniyi, OS; Friday, ET; Makinde, OV; Olaleye, SB, 2017)
"Gastric ulcers was induced in the animals of 12 groups with one untreated group being left as the control (Group I - control; given normal saline (NS))."1.46Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017)
"Gastric ulcers were induced in rats by applying acetic acid to the serosa of the stomach."1.43Glyprolines exert protective and repair-promoting effects in the rat stomach: potential role of the cytokine GRO/CINC-1. ( Andreeva, LA; Bakaeva, ZV; Myasoedov, NF; Sangadzhieva, AD; Tanaka, T; Tani, S; Torshin, VI; Wallace, JL, 2016)
"(-)-Linalool is a monoterpene constituent of many essential oils."1.43Beta-cyclodextrin enhanced gastroprotective effect of (-)-linalool, a monoterpene present in rosewood essential oil, in gastric lesion models. ( da Costa, DS; da Silva, FV; de Barros Fernandes, H; de Cássia Meneses Oliveira, R; de Lira, KL; de Sousa, AA; Lopes, MT; Oliveira, IS; Quintans-Júnior, LJ; Viana, AF, 2016)
"Twenty-eight gastric hyperalgesia rats and 20 control rats were used."1.39Desvenlafaxine succinate ameliorates visceral hypersensitivity but delays solid gastric emptying in rats. ( Chen, JD; Dai, F; Lei, Y; Li, S; Song, G, 2013)
"Gastric ulcers were induced by the serosal application of 100% acetic acid, and the areas of the ulcers were measured thereafter."1.39NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4(+)VEGFR1(+) cells to the ulcer granulation tissues. ( Ae, T; Amano, H; Eshima, K; Hosono, K; Ito, Y; Katada, C; Koizumi, W; Majima, M; Minamino, T; Ohno, T; Sato, T; Shibuya, M; Suzuki, T, 2013)
"Gastric ulcers were induced by serosal application of acetic acid in mice, and gastric tissues were processed for further evaluation."1.39High-mobility group box 1 inhibits gastric ulcer healing through Toll-like receptor 4 and receptor for advanced glycation end products. ( Arakawa, T; Fujiwara, Y; Higashimori, A; Nadatani, Y; Ohkawa, F; Shiba, M; Sogawa, M; Takeda, S; Takeuchi, K; Tanigawa, T; Tominaga, K; Watanabe, K; Watanabe, T; Yamagami, H, 2013)
"Gastric cancer was found in both the anterior and posterior walls of the corpus in all 43 mice."1.38Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model. ( Cao, H; Chen, D; Johannessen, H; Kodama, Y; Okabe, S; Takahashi, R; Wang, TC; Zhao, CM, 2012)
"It is important in treatment of gastric ulcers to not only prevent further ulcer formation but also enhance ulcer healing."1.37Stimulation of gastric ulcer healing by heat shock protein 70. ( Asano, T; Ishihara, T; Mizushima, T; Suemasu, S; Tanaka, K, 2011)
"Gastric ulcers were produced by focal and serosal application of acetic acid."1.37Stimulation of gastric ulcer healing by heat shock protein 70. ( Asano, T; Ishihara, T; Mizushima, T; Suemasu, S; Tanaka, K, 2011)
"It proved that DBXX granules showed good healing effect on the chronic gastric ulcer mice and significant effect on decreasing the side effect of chemotherapy of S180 tumor-bearing mice."1.37Activity of DBXX granules on anti-gastric ulcer and decreasing the side effect of chemotherapy in S180 tumor-bearing mice. ( Cao, Y; Han, N; Lin, X; Liu, Z; Xue, R; Yin, J, 2011)
"Chronic gastric ulcer was induced by an injection of 100% glacial acetic acid into the submucosal layer of the glandular stomach, then the area of all ulcers was added together as the ulcer index and inhibition rate of ulcer was calculated."1.37Activity of DBXX granules on anti-gastric ulcer and decreasing the side effect of chemotherapy in S180 tumor-bearing mice. ( Cao, Y; Han, N; Lin, X; Liu, Z; Xue, R; Yin, J, 2011)
"Gastric ulcers were produced by subserosal injection of acetic acid."1.36Enhancement of gastric ulcer healing and angiogenesis by cochinchina Momordica seed extract in rats. ( Jung, HC; Kang, JM; Kim, B; Kim, JH; Kim, JS; Kim, N; Lee, BY; Lee, HS; Lee, MK; Park, JH; Song, IS, 2010)
"Gastric ulcers were induced by the serosal application of 100% acetic acid, and the areas of the ulcers were measured thereafter."1.36Role of microsomal prostaglandin E synthase-1 in the facilitation of angiogenesis and the healing of gastric ulcers. ( Ae, T; Akira, S; Hattori, Y; Hosono, K; Koizumi, W; Majima, M; Minamino, T; Ohno, T; Sato, T; Suzuki, T; Uematsu, S, 2010)
"Contemporary medications used in the treatment of gastric ulcers involve the use of novel mucosal protective drugs."1.36Ginger extract and polaprezinc exert gastroprotective actions by anti-oxidant and growth factor modulating effects in rats. ( Ko, JK; Leung, CC, 2010)
" To assess the significance of this multiple probe approach, drug concentrations in each probe location were monitored after selected compounds were dosed to the ligated stomach by oral gavage."1.35The direct comparison of health and ulcerated stomach tissue: a multiple probe microdialysis sampling approach. ( Lunte, CE; Woo, KL, 2008)
"Carnosol was identified as a possible active constituent for the gastroprotective effect of HE."1.35Gastroprotective constituents of Salvia officinalis L. ( Baggio, CH; dos Santos, AC; dos Santos, EP; Freitas, CS; Heller, M; Horst, H; Marques, MC; Mayer, B; Micke, GA; Otuki, MF; Pizzolatti, MG; Twardowschy, A, 2009)
"Chronic gastric ulcers were induced in male Wistar rats by the application of 100% acetic acid to the serosal surface of the stomach on 60 sec."1.35[Influence of honey, royal jelly and propolis on accelerating acetate healing of experimental gastric ulcers in rats]. ( Belostotskiĭ, NI; Dubtsova, EA; Kas'ianenko, VI; Lazebnik, LB, 2009)
" No toxic effect was observed in all parameters evaluated."1.35Studies of gastric mucosa regeneration and safety promoted by Mouriri pusa treatment in acetic acid ulcer model. ( Andreo, M; Hiruma-Lima, CA; Kushima, H; Pellizzon, CH; Takahira, RK; Vasconcelos, PC; Vilegas, W, 2008)
"Gastric ulcers were induced by serosal application of absolute acetic acid."1.35Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis. ( Ae, T; Amagase, K; Arai, K; Hattori, Y; Hayashi, I; Hosono, K; Komine, R; Kurihara, H; Kurihara, Y; Majima, M; Mizuguchi, S; Oh-Hashi, Y; Ohno, T; Okabe, S; Saeki, T; Saigenji, K; Suzuki, T, 2008)
"Gastric ulcers were induced, and BM-derived cells, myofibroblasts, or phosphate-buffered saline were injected around ulcers."1.35Cultured bone marrow cell local implantation accelerates healing of ulcers in mice. ( Egawa, S; Hayashi, N; Iijima, H; Irie, T; Ishii, S; Kakiuchi, Y; Kawano, S; Nishida, T; Shinzaki, S; Tsuji, S; Tsujii, M; Tsutsui, S; Yasumaru, M; Yoshio, T, 2008)
"Gastric ulcers were induced in male rats by serosal application of acetic acid."1.34[Effect of mucosal protective on the quality of gastric ulcer healing]. ( Chen, K; Chen, SJ; Deng, YY; Liu, WL; Qian, Y; Si, JM; Sun, KK; Wang, LJ; Wu, JG; Zhu, YF, 2007)
"Aspirin enhance the recurrence of gastric ulcer."1.34Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007)
"Ulcer recurrence and poor healing may be critically important to the development of serious gastrointestinal complications in patients with long-term non-steroid anti-inflammatory drugs (NSAIDs)."1.34Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007)
"Gastric ulcers were induced with acetic acid in rats; aspirin was administrated by gavage from day 25 to day 54 after ulcer induction."1.34Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats. ( Guo, CJ; Huang, GP; Jia, BB; Wang, GZ; Wang, JF; Xie, CG; Yin, GL; Zhou, G, 2007)
"Hydrogen sulfide is an endogenous mediator that relaxes vascular smooth muscle, exhibits several antiinflammatory activities, and contributes to gastric mucosal defense."1.34Hydrogen sulfide enhances ulcer healing in rats. ( Dicay, M; Martin, GR; McKnight, W; Wallace, JL, 2007)
"Gastric ulcers were induced in male SD rats by serosal application of acetic acid for 60 sec."1.34Effect of dopamine on the healing of acetic acid-induced gastric ulcers in rats. ( Amagase, K; Nishikawa, K; Takeuchi, K, 2007)
"Ketorolac is a non-steroidal anti-inflammatory drug."1.34Ketorolac-dextran conjugates: synthesis, in vitro and in vivo evaluation. ( Chaturvedi, SC; Trivedi, P; Vyas, S, 2007)
"Ketorolac contents were evaluated by UV-spectrophotometric analysis."1.34Ketorolac-dextran conjugates: synthesis, in vitro and in vivo evaluation. ( Chaturvedi, SC; Trivedi, P; Vyas, S, 2007)
"Melatonin is a hormone involved in the transduction of photoperiodic information, and appears to modulate a variety of neural and endocrine functions."1.33Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes. ( Cevík, H; Ercan, F; Erkanli, G; Işman, CA; Yeğen, BC, 2005)
"Acute gastric ulcer was induced with single oral doses of indomethacin (20 mg/kg)."1.33Therapeutic effect of D-002 (abexol) on gastric ulcer induced experimentally in rats. ( Arruzazabala, L; Carbajal, D; Más, R; Molina, V, 2005)
"Mucosal inflammation is a crucial factor for the recurrence of peptic ulcer."1.33Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils. ( Osaka, T; Sakurai, K; Yamasaki, K, 2005)
"Ulcer recurrence was examined at 60, 100, and 140 days after production of acetic acid-induced gastric ulcers in rats."1.33Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils. ( Osaka, T; Sakurai, K; Yamasaki, K, 2005)
"Acetic acid ulcers were produced in the rat gastric corpus; non-ulcer rats served as controls."1.33Cell proliferation in the gastric epithelium of the ulcer rat. ( Helander, HF; Li, H, 2005)
"Gastric ulcer is a source of visceral pain."1.33Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006)
"Gastric ulcers were induced by luminal application of 60% acetic acid under surgical conditions."1.33Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006)
"Pathohistology of ulcer healing and recurrence was observed."1.33[Effects of jianwei yuyang granule on inflammatory reaction and NF-kappaB expression in rat gastric mucosa of ulcer healing and recurrence]. ( Cao, Y; Chen, YQ; Li, JB; Ling, JH; Pan, YZ; Shen, DZ, 2006)
"Gastric ulcer was induced in rat by acetic acid according Okeba's method with some modification and the recurrence model was induced by IL-1beta."1.33[Effects of jianwei yuyang granule on inflammatory reaction and NF-kappaB expression in rat gastric mucosa of ulcer healing and recurrence]. ( Cao, Y; Chen, YQ; Li, JB; Ling, JH; Pan, YZ; Shen, DZ, 2006)
"Gastric ulcers were produced by injecting 50 microl of 20% acetic acid into subserosa of the border between the fundic and antral gland areas."1.32Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor. ( Ichiba, M; Murawaki, Y; Shiota, G; Udagawa, A, 2003)
"The gastric ulcer was induced endoscopically with 1 mL of 40% acetic acid 12 days after inoculation of H."1.32Temporal increase in the gastric colonization of Helicobacter pylori after healing of acetic acid-induced gastric ulcer in a miniature pig. ( Iwata, M; Katsuta, M; Kikuchi, I; Koga, T; Okazaki, Y; Sato, K; Shimada, Y; Takahashi, K, 2003)
"Gastric ulcers were induced in rats and mice by the application of acetic acid and cryoinjury, respectively."1.32Roles of inducible nitric oxide synthase in the development and healing of experimentally induced gastric ulcers. ( Esumi, H; Nagata, H; Ogura, T; Sakurazawa, N; Sugita, M; Tatemichi, M, 2003)
"Gastric ulcers were induced in normal/NIDDM rats by various physical (2 hr cold restraint stress and 4 hr pylorus ligation) and chemical agents (ethanol, 1 ml/200 g, oral, 1 hr before; aspirin, 200 mg/kg, oral, 4 hr) and duodenal ulcers were induced by cysteamine (40 mg/200 g)."1.32Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats. ( Agrawal, VK; Aryya, NC; Dorababu, M; Goel, RK; Prabha, T; Priyambada, S, 2004)
" An initial dose-response study using 12."1.32Evaluation of Pongamia pinnata root extract on gastric ulcers and mucosal offensive and defensive factors in rats. ( Agrawal, VK; Dora Babu, M; Goel, RK; Prabha, T; Priyambada, S, 2003)
"Gastric ulcers were induced in male Wistar rats by applying acetic acid to the fundus of the stomach."1.31Mechanism of the antiulcerogenic effect of IL-11 on acetic acid-induced gastric ulcer in rats. ( Fukuda, E; Ito, M; Matsuu, M; Nakashima, M; Nakayama, T; Sekine, I; Shichijo, K; Wen, CY, 2002)
"Acetic acid was perfused into the gastric cavitties of 130 rats to produce animal model of /gastric ulcer."1.31[Expression and activity of cyclooxygenases-1 and -2 in acetic acid induced gastric ulcer in rats]. ( Guo, J; Koo, MW; Wang, J, 2001)
"Pentoxifylline has many anti-inflammatory properties including inhibition of production of tumor necrosis factor alpha (TNF-alpha)."1.31Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Kuroki, T; Shimizu, N; Watanabe, T, 2000)
"In untreated rats, acetic acid-induced gastric ulcers healed after 14 days and the electrophoretic band corresponding to connexin 32 appeared 4 days after ulcer induction."1.31The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000)
"Acetic acid was used to induce chronic gastric ulcers in rats, and a water extract of H."1.31The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats. ( Endo, C; Fujita, T; Kobayashi, I; Kushima, R; Kushima, W; Mine, T; Muraoka, H; Taki, R, 2000)
"Chronic gastric ulcers were induced using acetic acid and duodenal ulcers by cysteamine hydrochloride."1.31Effect of centrally administered prolactin on gastric and duodenal ulcers in rats. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001)
"The effect of hyperprolactinaemia, induced by two or four pituitary homografts under the kidney capsule, on gastric and duodenal ulcers has been studied."1.31Effect of hyperprolactinaemia as induced by pituitary homografts under kidney capsule on gastric and duodenal ulcers in rats. ( Abraham, BK; Asad, M; Balasinor, N; Koumaravelou, K; Ramaswamy, S; Shewade, DG, 2001)
"Chronic gastric ulcers were induced using acetic acid and duodenal ulcers by mercaptamine hydrochloride."1.31Effect of hyperprolactinaemia as induced by pituitary homografts under kidney capsule on gastric and duodenal ulcers in rats. ( Abraham, BK; Asad, M; Balasinor, N; Koumaravelou, K; Ramaswamy, S; Shewade, DG, 2001)
"Chronic gastric ulcers were induced using acetic acid and duodenal ulcers by cysteamine hydrochloride."1.31Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001)
"Indomethacin treatment showed a tendency to delay ulcer healing."1.31Influence of Helicobacter pylori infection on healing and relapse of acetic acid ulcers in Mongolian gerbils. ( Ebata, M; Keto, Y; Okabe, S; Tomita, K, 2002)
"Gastric ulcers were induced by serosal application of an acetic acid solution."1.31Influence of Helicobacter pylori infection on healing and relapse of acetic acid ulcers in Mongolian gerbils. ( Ebata, M; Keto, Y; Okabe, S; Tomita, K, 2002)
" The effects of long-term administration of NS-398 on gastric ulcers were examined."1.30Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice. ( Akamatsu, T; Kasuga, M; Matsuda, K; Mizuno, H; Noguchi, H; Sakamoto, C; Uchida, T; Wada, K, 1997)
"No recurrence was found in the rats treated with 0."1.30Role of neutrophils in a rat model of gastric ulcer recurrence caused by interleukin-1 beta. ( Arakawa, T; Fukuda, T; Higuchi, K; Kobayashi, K; Watanabe, T, 1997)
"In acetic acid-treated rats, this activity increased to 2."1.30Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997)
"Gastric ulcer was induced by injecting 20 microliters glacial acetic acid into gastric wall of rat stomachs."1.30Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997)
"In the model of adjuvant arthritis VUFB-16066 improves most of disease symptoms including immunopathological disturbances, which indicates possible disease-modifying activity of the drug."1.30Pharmacological profile of the novel potent antirheumatic 4-(2',4'-difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic acid. ( Andĕrova, E; Jandera, A; Kuchar, M; Panajotova, V, 1997)
"Pretreatment with allopurinol (Allo, 5 mg/kg, i."1.30Mechanistic study of adverse actions of cigarette smoke exposure on acetic acid-induced gastric ulceration in rats. ( Cho, CH; Chow, JY; Ma, L, 1998)
"Gastric ulcers were induced in anesthetized rats by briefly exposing the mucosal surface to 0."1.30Phosphatidylcholine-associated aspirin accelerates healing of gastric ulcers in rats. ( Kurinets, A; Lichtenberger, LM, 1998)
"Gastric ulcers were induced by serosal application of acetic acid."1.30Bacteria rapidly colonize and modulate healing of gastric ulcers in rats. ( Buret, A; Elliott, SN; McKnight, W; Miller, MJ; Wallace, JL, 1998)
" Heparin in the doses of 100, 500, and 1000 U/kg were administered intravenously through the tail vein once daily, starting 1 day after ulcer induction for 7 days in the dose-response experiment or heparin 1000 U/kg at a time schedule of 3, 5, and 7 days in the time-response study, respectively."1.30Healing effects of heparin on acetic acid-induced gastric ulcers in rats. ( Cho, CH; Li, Y; Mei, QB, 1998)
"Portal hypertension was induced by staged portal vein ligation."1.30Delayed healing of acetic-acid-induced gastric ulcer in portal hypertensive rats. ( Baatar, D; Bandoh, T; Kitano, S; Ninomiya, K; Tsuboi, S; Yoshida, T, 1999)
"Gastric ulcers were induced by application of acetic acid to the serosal surface of the stomach."1.30Delayed healing of acetic-acid-induced gastric ulcer in portal hypertensive rats. ( Baatar, D; Bandoh, T; Kitano, S; Ninomiya, K; Tsuboi, S; Yoshida, T, 1999)
" The results suggest that modification of the oral dose of YJA-20379-8 may not be required in gastric ulcer patients if the present rat pharmacokinetic data could be extrapolated to man."1.30Gastrointestinal absorption of a new reversible proton pump inhibitor, YJA-20379-8, and its pharmacokinetics after oral administration in acetic acid-induced gastric ulcer in rats. ( Chang, MS; Chung, SY; Han, KS; Kim, HJ; Kim, J; Lee, MG, 1999)
" accelerated the chronic ulcer healing with a bell-shaped dose-effect curve and the best dosage was 10 kU."1.30Effect of recombinant human basic fibroblast growth factor on stomach ulcers in rats and mice. ( Gao, MT; Li, WG; Rao, CM; Wang, JZ; Wu, YJ, 1999)
"Gastric ulcers were induced by luminal application of an acetic acid solution (60%, 0."1.29Changes in gastric function and healing of chronic gastric ulcers in aged rats. ( Okabe, S; Tsukimi, Y, 1995)
"Gastric ulcers were produced on the anterior wall of the stomach of male Sprague-Dawley rats by submucosal injection of 20% acetic acid."1.29Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats. ( Kondo, M; Matsuyama, K; Naito, Y; Nishimura, S; Yagi, N; Yoshikawa, T, 1995)
"In the adjuvant arthritis test, the ED30 value (1."1.29Anti-inflammatory effects of etodolac: comparison with other non-steroidal anti-inflammatory drugs. ( Fujisawa, H; Inoue, K; Inoue, Y; Kimura, K; Kyoi, T; Motonaga, A; Ueda, F, 1994)
"Gastric ulcers were produced by luminal application of 60% acetic acid (0."1.29Validity of kissing gastric ulcers induced in rats for screening of antiulcer drugs. ( Okabe, S; Tsukimi, Y, 1994)
"Gastric ulcers were induced by application of acetic acid using a standard technique."1.29Effects of misoprostol on delayed ulcer healing induced by aspirin. ( Andrews, FJ; O'Brien, PE; Penney, AG, 1994)
"Gastric ulcers were produced 5 days after submucosal injection of 20% acetic acid (0."1.29Effect and mechanism of sucralfate on healing of acetic acid-induced gastric ulcers in rats. ( Ogihara, Y; Okabe, S, 1993)
"Gastric ulcers were induced in rats by acetic acid treatment, and the mast cell kinetics in the lesions were studied."1.29Increase in mucosal and connective tissue-type mast cells in the stomach with acetic acid-induced ulcer in rat. ( Arizono, N; Bamba, T; Hattori, T; Nakajima, S, 1996)
"The influence of KU-1257 on the recurrence and relapse of acetic acid ulcers in rats was investigated grossly and histologically in comparison with that of cimetidine."1.29[Influence of KU-1257 on the recurrence and relapse of acetic acid-induced chronic gastric ulcers in rats]. ( Kobayashi, F; Ohkubo, H; Ohsawa, A; Sekiguchi, H; Taga, F, 1996)
"Gastric ulcers were induced in young, adult, and aged rats using serosal or mucosal (kissing ulcers) application of acetic acid."1.29Influence of age on natural and delayed healing of experimentally-induced gastric ulcers in rats. ( Andrews, FJ; O'Brien, PE; Penney, AG, 1996)
"The effect of a proton pump inhibitor, omeprazole (OPZ), in combination with mouse epidermal growth factor (EGF), on the healing of chronic gastric ulcers induced by acetic acid in submandibular glands removed rats (SMR rat) was investigated."1.28[Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats]. ( Imai, S; Itoh, M; Joh, T; Takeuchi, T; Yokoyama, Y, 1992)
"Ebrotidine is a novel H2-receptor antagonist that exhibits both gastroprotective and ulcer-healing properties."1.28Gastroprotective and ulcer-healing activities of a new H2-receptor antagonist: ebrotidine. ( Brzozowski, T; Konturek, SJ; Majka, J, 1992)
" Chronic administration of hydrocortisone sodium phosphate resulted in a significant delay of ulcer healing induced by acetic acid."1.28Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991)
"Chronic gastric ulcers were produced in male Wistar rats, weighing 180 g, by the application of 100% acetic acid."1.28Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991)
" Chronic administration of HC sodium phosphate resulted in a significant delay of ulcer healing induced by acetic acid."1.28Effects of prostaglandins on hydrocortisone-induced delayed healing of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991)
"Chronic gastric ulcers were produced in male Wistar rats, weighing 180 g, by serosal application of 100% acetic acid."1.28Effects of prostaglandins on hydrocortisone-induced delayed healing of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991)
"Gastric ulcers were induced 5 days after submucosal injection of an acetic acid solution into the stomachs of rats."1.28Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats. ( Hirose, H; Okabe, S; Takeuchi, K, 1991)
" This suggests that further stimulation of ulcer healing may be expected if EGF is given with an acid-suppressive agent or with an agent allowing EGF to remain in rat gastric lumen at high concentrations."1.28Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat. ( Endoh, K; Imai, S; Itoh, M; Iwai, A; Joh, T; Kawai, T; Matsusako, K; Takeuchi, T; Yasue, N; Yokoyama, Y, 1990)
"Gastric ulcers were induced by subserosal injection of acetic acid, and confirmed by endoscopy on the third day."1.28Prolylhydroxylase and collagenase activities in the healing of acetic acid-induced gastric ulcers in rats and the effects of cimetidine and elcatonin. ( Komatsu, K; Kurose, I; Maruyama, K; Oda, M; Okazaki, I; Tsuchiya, M, 1989)
"Gastric ulcers were produced 5 days after injecting 20% acetic acid (0."1.28Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin. ( Okabe, S; Takeuchi, K; Wang, JY; Yamasaki, S, 1989)
"Cetraxate was effective in preventing only stress-induced ulcers and had almost no effect on other experimental ulcers."1.27Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals. ( Aratani, S; Enomoto, H; Kimura, K; Mimura, K; Nomura, A; Ueda, F, 1984)
"Cimetidine was effective in preventing stress- and acetic acid-induced ulcers but had no significant effect on Shay, indomethacin-induced and histamine-induced ulcers."1.27Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals. ( Aratani, S; Enomoto, H; Kimura, K; Mimura, K; Nomura, A; Ueda, F, 1984)
"Chronic gastric ulcers were produced by injection of 20% acetic acid (0."1.27Effects of trimoprostil on healing and recurrence of acetic acid-induced gastric ulcer in rats. ( Nakamura, K; Umeda, Y, 1986)

Research

Studies (370)

TimeframeStudies, this research(%)All Research%
pre-199037 (10.00)18.7374
1990's108 (29.19)18.2507
2000's120 (32.43)29.6817
2010's83 (22.43)24.3611
2020's22 (5.95)2.80

Authors

AuthorsStudies
Fagundes, FL1
Pereira, QC1
Zarricueta, ML1
Dos Santos, RC2
Wang, X1
Wang, S1
Hou, A1
Yu, H1
Zhang, J2
Zheng, S1
Zhang, S1
Lv, J1
Dong, J1
Yang, L2
Kuang, H1
Jiang, H1
de Oliveira, BMM1
Serpa, PZ1
da Costa Zanatta, ME1
Aires, BA1
Steffler, AM1
Somensi, LB4
Cury, BJ2
Dos Santos, AC4
Venzon, L3
Boeing, T5
Mota da Silva, L1
Roman Junior, WA1
Meurer, MC1
Dos Santos França, TC1
Longo, B2
Mariott, M2
Mariano, LNB2
Cazarin, CA1
Pereira, LN1
de Souza, MM1
da Silva, LM10
Wang, C4
Tan, L1
Liu, J5
Fu, D1
Li, P2
Li, Z2
Ipek, E1
Ekren Aşıcı, GS1
Epikmen, ET1
Abbak, M1
Kurt, BK1
Özsoy, ŞY1
Tunca, R1
Jiang, S1
Zheng, H1
An, Y1
Zheng, W1
Lin, H2
Wang, G1
Wang, F2
Kulikova, OI1
Stvolinsky, SL1
Migulin, VA1
Andreeva, LA2
Nagaev, IY1
Lopacheva, OM1
Kulichenkova, KN1
Lopachev, AV1
Trubitsina, IE1
Fedorova, TN1
Yuan, Y2
Pan, H1
Hsu, AC1
Chen, J1
Xing, M1
Fu, R1
Liu, Y1
Wang, P1
Ma, P1
Zhu, C1
Fan, D1
Garabadu, D1
Singh, S1
Gautam, T1
Ajayi, AF1
Olaleye, SB3
Guo, Y1
Du, Y1
Xie, L1
Pu, Y1
Yuan, J1
Wang, Z2
Zhang, T1
Wang, B1
Panda, SS1
Girgis, AS1
Honkanadavar, HH1
George, RF1
Srour, AM1
Costa, P1
Meurer, M1
França, TCS1
Gouveia, L1
de Bassi, AC1
Steimbach, V1
de Souza, P2
de Almeida, MO1
Arruda, C1
de Andrade, SF5
Bastos, JK1
Odukanmi, A1
Salami, AT1
Olanrewaju, TR1
Zalecki, M2
Juranek, J1
Pidsudko, Z1
Mogielnicka-Brzozowska, M1
Kaleczyc, J1
Franke-Radowiecka, A2
Al-Ostoot, FH1
Grisha, S1
Mohammed, YHE1
Vivek, HK1
Ara Khanum, S1
Wu, H1
Wei, M1
Li, N1
Lu, Q1
Shrestha, SM1
Tan, J1
Zhang, Z3
Wu, G1
Shi, R1
Bueno, G2
Chavez Rico, SL1
Périco, LL2
Ohara, R2
Rodrigues, VP2
Emílio-Silva, MT1
Assunção, R1
Machado da Rocha, LR1
Nunes, DS1
Besten, MA1
Heiden, G1
Lima Camargo, AC1
Justulin, LA1
Hiruma-Lima, CA4
Siwe, GT2
Maharjan, R1
Amang, AP2
Mezui, C2
Zondegoumba, NE1
Enow-Orock, GE2
Choudhary, MI1
Tan, PV2
Plywacz, A1
Antushevich, H1
Han, T1
Tang, Y1
Li, J2
Xue, B1
Gong, L1
Yu, X1
Liu, C1
Uchida, M8
Kobayashi, O1
Shimizu, K2
Adeniyi, OS1
Makinde, OV1
Friday, ET1
Magierowski, M1
Magierowska, K1
Hubalewska-Mazgaj, M1
Sliwowski, Z1
Ginter, G1
Pajdo, R3
Chmura, A1
Kwiecien, S4
Brzozowski, T7
Kalayci, M1
Kocdor, MA1
Kuloglu, T1
Sahin, İ1
Sarac, M1
Aksoy, A1
Yardim, M1
Dalkilic, S1
Gursu, O1
Aydin, S2
Akkoc, RF1
Ugras, M1
Artas, G1
Ozercan, İH1
Ugur, K1
Pinz, MP1
Reis, AS1
de Oliveira, RL1
Voss, GT1
Vogt, AG1
Sacramento, MD1
Roehrs, JA1
Alves, D1
Luchese, C1
Wilhelm, EA1
Wang, Y2
Wang, SL1
Zhang, JY1
Song, XN1
Zhang, ZY1
Li, JF1
Li, S2
Emakoua, J1
Mbah, G1
Nkwengoua, EZ1
Zapata-Morales, JR1
Alonso-Castro, ÁJ1
Granados-Soto, V1
Sánchez-Enriquez, S1
Isiordia-Espinoza, MA1
Hamdi, A1
Majouli, K1
Abdelhamid, A1
Marzouk, B1
Belghith, H1
Chraief, I1
Bouraoui, A1
Marzouk, Z1
Heyden, YV1
Kolgazi, M1
Ozdemir-Kumral, ZN1
Cantali-Ozturk, C1
Demirci, EK1
Yuksel, M3
Sirvanci, S1
Yegen, BC5
Dos Santos, CBR1
da Silva Ramos, R1
Ortiz, BLS1
da Silva, GM1
Giuliatti, S1
Balderas-Lopez, JL1
Navarrete, A1
Carvalho, JCT1
Navarro, L1
Rosell, G1
Sánchez, S1
Boixareu, N1
Pors, K1
Pouplana, R1
Campanera, JM1
Pujol, MD1
Yu, Y2
Cai, Q2
Jia, TZ2
Nunes, VVA1
Camargo, ACL1
Justulin Júnior, LA1
Steimbach, VMB1
da Rocha, LRM1
Vilegas, W5
Dos Santos, C1
Almeida, GVB1
Arunachalam, K1
Balogun, SO4
Pavan, E2
Ascêncio, SD2
Soares, IM2
Zanatta, AC1
Macho, A1
Oliveira Martins, DT1
Bang, BW1
Park, D1
Kwon, KS1
Lee, DH1
Jang, MJ1
Park, SK1
Kim, JY1
Yoshioka, T1
Fukuda, A1
Araki, O1
Ogawa, S1
Hanyu, Y1
Matsumoto, Y1
Yamaga, Y1
Nakanishi, Y1
Kawada, K1
Sakai, Y1
Chiba, T3
Seno, H1
Viana, AFSC1
Lopes, MTP1
Oliveira, FTB1
Nunes, PIG1
Santos, VG1
Braga, AD1
Silva, ACA1
Sousa, DP1
Viana, DA1
Rao, VS4
Oliveira, RCM1
Santos, FA2
Ugwah, MO1
Ugwah-Oguejiofor, CJ1
Etuk, EU1
Bello, SO1
Aliero, AA1
Pezzini, BC1
Bolda Mariano, LN1
Cechinel-Filho, V2
Farrag, ARH1
Abdallah, HMI1
Khattab, AR1
Elshamy, AI1
Gendy, AEGE1
Mohamed, TA1
Farag, MA1
Efferth, T1
Hegazy, MF1
Xue, Z1
Shi, G1
Fang, Y1
Liu, X1
Zhou, X1
Feng, S1
Zhao, L1
Dharmani, P1
De Simone, C1
Chadee, K1
Klein-Júnior, LC1
Santin, JR2
Lemos, M1
Silveira, AC1
Rocha, JA1
Beber, AP1
Wagner, TM1
Bresolin, TM1
Bella-Cruz, A1
Faloni de Andrade, S2
Xu, JJ1
Huang, P1
Wu, QH1
Cao, HY1
Wen, S1
Mishra, V1
Shukla, A1
Pandeti, S1
Barthwal, MK1
Pandey, HP1
Palit, G1
Narender, T1
Dai, F1
Lei, Y1
Song, G1
Chen, JD1
Sato, T2
Amano, H1
Ito, Y2
Eshima, K1
Minamino, T2
Ae, T3
Katada, C1
Ohno, T3
Hosono, K3
Suzuki, T3
Shibuya, M1
Koizumi, W2
Majima, M3
Mei, XT1
Xu, DH1
Xu, SK1
Zheng, YP1
Xu, SB1
Engevik, AC2
Feng, R1
Zavros, Y2
Nadatani, Y1
Watanabe, T6
Tanigawa, T2
Ohkawa, F1
Takeda, S1
Higashimori, A1
Sogawa, M1
Yamagami, H1
Shiba, M1
Watanabe, K1
Tominaga, K3
Fujiwara, Y3
Takeuchi, K7
Arakawa, T8
Szlachcic, A2
Majka, J5
Strzalka, M1
Szmyd, J1
Ptak-Belowska, A1
Kumral, ZN1
Memi, G1
Ercan, F3
Berté, PE1
da Silva Lopes, J1
Comandulli, NG1
Rangel, DW1
Monache, FD1
Filho, VC1
Niero, R2
Maria-Ferreira, D2
Mendes, DA2
Cabrini, Dde A1
Nascimento, AM1
Iacomini, M3
Cipriani, TR3
Santos, AR1
Werner, MF5
Baggio, CH6
Tianjiao, L1
Shuai, W1
Xiansheng, M1
Yongrui, B1
Shanshan, G1
Bo, L1
Lu, C1
Lei, W1
Xiaorong, R1
Nakao, K1
Ro, A1
Kibayashi, K1
Aihara, E4
Closson, C1
Matthis, AL1
Schumacher, MA1
Ottemann, KM1
Montrose, MH1
Martins, JL1
Rodrigues, OR1
da Silva, DM1
Galdino, PM1
de Paula, JR1
Romão, W1
da Costa, HB1
Vaz, BG1
Ghedini, PC1
Costa, EA1
Dhokchawle, BV1
Bhandari, AB1
Pinto, LA1
Cordeiro, KW1
Carrasco, V1
Carollo, CA1
Cardoso, CA1
Argadoña, EJ1
Freitas, Kde C1
Pinheiro Silva, L1
Damacena de Angelis, C1
Bonamin, F1
Kushima, H2
José Mininel, F1
Campaner Dos Santos, L1
Karina Delella, F1
Luis Felisbino, S1
Regina Machado da Rocha, L1
Aparecido Dos Santos Ramos, M1
Maria Bauab, T1
Toma, W3
Akiko Hiruma-Lima, C1
Jiang, N1
Ma, MY1
Min, DY1
Steimbach, VM1
Silveria, AC1
Cechinel Filho, V1
Adzu, B1
Aguiar, RW1
Ribeiro, RV1
Beserra, ÂM3
de Oliveira, RG2
da Silva, LI1
Damazo, AS2
Martins, DT4
Ribeiro, AR1
Diniz, PB1
Pinheiro, MS1
Albuquerque-Júnior, RL1
Thomazzi, SM1
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Umeda, N1
Kuwahara, Y1
Uspenskiĭ, VM1
Pigarevskiĭ, VE1
Sarychev, ES1
Golofeevskiĭ, VIu1
Brandt, W1
Buntrock, P1
Hasebe, T1
Harasawa, S1
Miwa, T1
Shibata, T1
Inayama, S1
Yamasaki, S1
Li, HQ1
Kawano, J1
Sato, S1
Kamata, T1
Nakanishi, J1
Ishikura, Y2
Tsuchiya, S1
Mimura, T1
Tsujikawa, K1
Yasuda, N1
Nakajima, H1
Haruyama, M1
Ohmura, T1
Okabe, M1
Mrzozowski, T1
Pawlik, W1
Amirov, NSh1
Jino, H1
Nishida, A1
Umeda, Y1
Tabusa, F1
Komatsu, M1
Morita, S1
Kanbe, T1
Nakagawa, K1
Fujii, A2
Hoshina, K1
Yamazaki, N1
Takeshita, T1
Naruchi, T1
Ohno, H1
Noguchi, M1
Takayanagi, N1
Inatomi, N1
Hirata, T1
Sino, A1
Maki, Y1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Single Arm, Open-label Pilot Trial Examining the Effects of Pau d' Arco on Primary Dysmenorrhea in Reproductive Age Women[NCT04245540]Early Phase 112 participants (Actual)Interventional2019-07-30Completed
Effects of Lavender Aromatherapy and Cold Application on Pain During Drain Removal[NCT04798040]121 participants (Actual)Interventional2021-09-01Completed
Elderly Patients With Dementia in the Department of Acute Geriatrics: Pilot Study, Monocentric, Randomized Use of Aromatherapy as a Complementary Treatment to Psychopharmacotherapy in Psychological Disorders and BPSD Behavior[NCT03662360]32 participants (Actual)Interventional2018-05-20Completed
A Randomized Prospective Placebo-Controlled Study of the Effects of Lavender Aromatherapy on Preoperative Anxiety in Breast Surgery Patients[NCT01837966]93 participants (Actual)Interventional2013-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Role of Essential Oil Therapy in Environmental Diffusion as a Complement of Psychotropic Drugs in the Management of Psychological and Behavioral Disorders (BPSD)

"The Neuropsychiatric Inventory - Nursing Home Version (NPI-NH) test will characterize the neuropsychiatric and psychopathological symptoms of patients affected by dementia.~Events as delirium, anxiety, depression, etc. will be recorded by the frequency (from 0, absence, to 4, high frequency) and the seriousness (from 0, absence, to 3, high). The total score of the NPI-NH is given by the frequency x (multiply) seriousness (total score for each event has a range from 0 to 12). The patient final score will be given by the sum of the score of the 12 events. For each patient will be given a total score from 0 to 144.~NPI NH score has been collected in both control and aromatherapy groups at T1 and T3, in patients who needed and who did not needed Pro Re Nata." (NCT03662360)
Timeframe: Time 1 (baseline) and Time 3 (day 7)

,
Interventionscore on a scale (Mean)
T1 NPI score in patients do not need Pro Re NataT3 NPI score in patients needed Pro Re NataT3 NPI score in patients do not need Pro Re Nata
GROUP A - Control Group21.8132.8720.00
GROUP B - Aromatherapy Group25.9316.57.25

Role of Essential Oil Therapy in Environmental Diffusion in Professional Caregiver Distress Linked to BPSD

NPI-NH assess the psychological distress in physicians, nurses and nursing assistants who managed the patients. It has a score from 0 (no discomfort) to score of 5 (extreme discomfort). The psychological distress is measured for each of the 12 events in the NPI-NH scale, for a total score from 0 to 60. (NCT03662360)
Timeframe: Time 1 (baseline) and Time 3 (day 7)

,
Interventionscore on a scale (Mean)
T1 NPI NH physicians in pts with PRNT1 NPI NH physicians in pts without PRNT1 NPI NH nurses in pts with PRNT1 NPI NH nurses in pts without PRNT1 NPI NH nursing assistants in pts with PRNT1 NPI NH nursing assistants in pts without PRNT3 NPI NH physician in pts with PRNT3 NPI NH physician in pts without PRNT3 NPI NH nurses in pts with PRNT3 NPI NH nurses in pts without PRNT3 NPI NH nursing assistants in pts with PRNT3 NPI NH nursing assistants in pts without PRN
GROUP A - Control Group4.191.609.636.4011.007.106.003.2012.009.3013.199.90
GROUP B - Aromatherapy Group5.644.1311.6410.1312.2110.882.640.885.794.255.934.38

Anxiety Reduction

We hoped to show that lavender aroma therapy reduces preoperative anxiety in patients undergoing breast. The Trait subscale (STAI-TRAID) of the Spielberger State-Trait Anxiety Inventory was administered before and after 10 minutes of aromatherapy treatment pre-surgery. The TRAIT subscale contains 20 questions scored on a Likert scale from 1-4; item scores are summed for a total score ranging from 20 to 80, with higher scores indicating higher anxiety. Change in anxiety was calculated as the score pre-aromatherapy minus the score post-aromatherapy. Higher positive change scores indicate greater reductions in anxiety. (NCT01837966)
Timeframe: 20 minutes before surgery (pre aromatherapy) and 10 minutes before surgery (post aromatherapy)

Interventionunits on a scale (Mean)
Lavender Oil0.89
Placebo.74

Trials

1 trial available for acetic acid and Gastric Ulcer

ArticleYear
Are probiotics effective in the treatment of fungal colonization of the gastrointestinal tract? Experimental and clinical studies.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57 Suppl 9

    Topics: Acetic Acid; Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antif

2006

Other Studies

369 other studies available for acetic acid and Gastric Ulcer

ArticleYear
Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation.
    Nutrients, 2021, Sep-23, Volume: 13, Issue:10

    Topics: Acetic Acid; Animals; Anthocyanins; Antioxidants; Biomarkers; Cyclooxygenase 1; Disease Models, Anim

2021
The effect of anti-alcoholic gastric ulcer before and after vinegar-processed Yuanhu Zhitong prescription based on spectral-effect relationship.
    Biomedical chromatography : BMC, 2022, Volume: 36, Issue:8

    Topics: Acetic Acid; Chromatography, Liquid; Drugs, Chinese Herbal; Eosine Yellowish-(YS); Hematoxylin; Huma

2022
Gastroprotective and gastric healing effects of the aqueous extract of Casearia sylvestris in rodents: Ultrasound, histological and biochemical analyzes.
    Journal of ethnopharmacology, 2022, Nov-15, Volume: 298

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Casearia; Ethanol; Female; Gastric Mucosa; Mice; Mucins; Ni

2022
Geraniol accelerates the gastric healing, minimizes ulcers recurrence, and reduces anxiolytic-like behavior in ulcerated rodents by oral or inhaled route.
    Inflammopharmacology, 2022, Volume: 30, Issue:6

    Topics: Acetic Acid; Acyclic Monoterpenes; Animals; Anti-Anxiety Agents; Anti-Ulcer Agents; Gastric Mucosa;

2022
Integrated Metabolomics and Network Pharmacology to Decipher the Latent Mechanisms of Protopanaxatriol against Acetic Acid-Induced Gastric Ulcer.
    International journal of molecular sciences, 2022, Oct-11, Volume: 23, Issue:20

    Topics: Acetic Acid; Animals; Biomarkers; Epidermal Growth Factor; Ginsenosides; Interleukin-6; Metabolomics

2022
Evaluation of Acetic Acid-Induced Chronic Gastric Ulcer Healing by Propionyl-L-Carnitine Administration.
    Chemistry & biodiversity, 2023, Volume: 20, Issue:7

    Topics: Acetic Acid; Animals; Cyclooxygenase 2; Epidermal Growth Factor; Rats; Rats, Wistar; Stomach Ulcer;

2023
Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats.
    Journal of ethnopharmacology, 2024, Jan-30, Volume: 319, Issue:Pt 3

    Topics: Acetic Acid; Animals; Gastrointestinal Microbiome; Male; Metabolome; Rats; Rats, Wistar; Stomach Ulc

2024
A new derivative of acetylsalicylic acid and carnosine: synthesis, physical and chemical properties, biological activity.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2020, Volume: 28, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Carnosine; Erythrocytes; Hemolysis;

2020
Protective Effect of Ocotillol, the Derivate of Ocotillol-Type Saponins in
    International journal of molecular sciences, 2020, Apr-08, Volume: 21, Issue:7

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Endothelin-1; Ginsenosides; Male;

2020
Human-like collagen promotes the healing of acetic acid-induced gastric ulcers in rats by regulating NOS and growth factors.
    Food & function, 2020, May-01, Volume: 11, Issue:5

    Topics: Acetic Acid; Animals; Cell Line; Cell Movement; Cell Proliferation; Collagen; Drug Administration Sc

2020
    Journal of dietary supplements, 2021, Volume: 18, Issue:3

    Topics: Acetic Acid; Animals; Catalase; Gastric Mucosa; Glutathione; Male; Manilkara; Plant Bark; Plant Extr

2021
Immunohistochemical Studies of Age-Related Changes in Cell Proliferation and Angiogenesis during the Healing of Acetic Acid-Induced Gastric Ulcers in Rats.
    TheScientificWorldJournal, 2020, Volume: 2020

    Topics: Acetic Acid; Age Factors; Animals; Biomarkers; Cell Proliferation; ErbB Receptors; Factor VIII; Immu

2020
Effects of Paeonol and Gastroretention Tablets of Paeonol on Experimental Gastric Ulcers and Intestinal Flora in Rats.
    Inflammation, 2020, Volume: 43, Issue:6

    Topics: Acetic Acid; Acetophenones; Animals; Antioxidants; Catalase; Gastric Acid; Gastric Mucosa; Gastroint

2020
Synthesis of new ibuprofen hybrid conjugates as potential anti-inflammatory and analgesic agents.
    Future medicinal chemistry, 2020, Volume: 12, Issue:15

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygena

2020
Gastric healing effect of p-coumaric acid isolated from Baccharis dracunculifolia DC on animal model.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Baccharis; Catalase; Cell Line; Cell Proliferation; Cell Su

2021
Exposure to Mosquito Coil Smoke Delays Healing of Acetic Acid Induced Gastric Ulcer in Male Wistar Rats.
    Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, 2020, Jun-30, Volume: 35, Issue:1

    Topics: Acetic Acid; Animals; Culicidae; Gastric Mucosa; Insecticides; Male; Oxidative Stress; Rats, Wistar;

2020
Inferior vagal ganglion galaninergic response to gastric ulcers.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Acetic Acid; Animals; Galanin; Ganglia, Parasympathetic; Receptors, Galanin; RNA, Messenger; Stomach

2020
Molecular docking and synthesis of caffeic acid analogous and its anti-inflammatory, analgesic and ulcerogenic studies.
    Bioorganic & medicinal chemistry letters, 2021, 02-01, Volume: 33

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Carrageena

2021
Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Acetic Acid; Administration, Oral; Animals; Clopidogrel; Injections, Intraperitoneal; Male; Peptide

2020
The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity.
    Journal of ethnopharmacology, 2021, May-10, Volume: 271

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Baccharis; Brazil; Caspases; Cyclooxygenase 1; Cyclooxygena

2021
Eremomastax speciosa (Hochst.) Cufod. counteracts the delaying effect of indomethacin on Helicobacter pylori-associated chronic gastric ulcers healing.
    Journal of ethnopharmacology, 2021, Oct-28, Volume: 279

    Topics: Acanthaceae; Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Disease Models, Animal; Dose-Res

2021
Cocaine and Amphetamine Regulated Transcript (CART) Expression Changes in the Stomach Wall Affected by Experimentally Induced Gastric Ulcerations.
    International journal of molecular sciences, 2021, Jul-12, Volume: 22, Issue:14

    Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Enteric Nervous System; Female; Myenteric Plexus; Nerve

2021
Nitric oxide donor protects against acetic acid-induced gastric ulcer in rats via S-nitrosylation of TRPV1 on vagus nerve.
    Scientific reports, 2017, 05-18, Volume: 7, Issue:1

    Topics: Acetic Acid; Animals; Dose-Response Relationship, Drug; Membrane Potentials; Neurons; Nitric Oxide;

2017
Gastric emptying after artificial ulceration in rats: differences due to the site of the ulcer and the effects of prokinetic drugs.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2017, Volume: 53, Issue:0

    Topics: Acetic Acid; Animals; Benzamides; Breath Tests; Dose-Response Relationship, Drug; Gastric Emptying;

2017
Effects of quinine on gastric ulcer healing in Wistar rats.
    Journal of complementary & integrative medicine, 2017, Jun-29, Volume: 14, Issue:4

    Topics: Acetic Acid; Animals; Cinchona; Gastric Mucosa; Inflammation; Lipid Peroxidation; Male; Mucus; Oxida

2017
Carbon monoxide released from its pharmacological donor, tricarbonyldichlororuthenium (II) dimer, accelerates the healing of pre-existing gastric ulcers.
    British journal of pharmacology, 2017, Volume: 174, Issue:20

    Topics: Acetic Acid; Animals; Carbon Monoxide; Cyclooxygenase 2; Epidermal Growth Factor; ErbB Receptors; Ga

2017
Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer.
    Life sciences, 2017, Oct-01, Volume: 186

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Disease Models, Animal; Dose-Response Relationship, Drug; G

2017
7-Chloro-4-phenylsulfonyl quinoline, a new antinociceptive and anti-inflammatory molecule: Structural improvement of a quinoline derivate with pharmacological activity.
    Regulatory toxicology and pharmacology : RTP, 2017, Volume: 90

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Croton Oil; Edema; Hot Temperature; Huma

2017
Anti-ulcer and anti-Helicobacter pylori potentials of the ethyl acetate fraction of Physalis alkekengi L. var. franchetii (Solanaceae) in rodent.
    Journal of ethnopharmacology, 2018, Jan-30, Volume: 211

    Topics: Acetates; Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Ul

2018
Healing and Antisecretory Effects of Aqueous Extract of
    BioMed research international, 2017, Volume: 2017

    Topics: Acanthaceae; Acetic Acid; Animals; Antioxidants; Disease Models, Animal; Gastric Mucosa; Humans; Ind

2017
Assessment of the antinociceptive and ulcerogenic activity of the tapentadol-diclofenac combination in rodents.
    Drug development research, 2018, Volume: 79, Issue:1

    Topics: Acetic Acid; Analgesics; Animals; Diclofenac; Dose-Response Relationship, Drug; Drug Synergism; Male

2018
Pharmacological activities of the organic extracts and fatty acid composition of the petroleum ether extract from Haplophyllum tuberculatum leaves.
    Journal of ethnopharmacology, 2018, Apr-24, Volume: 216

    Topics: Acetic Acid; Alkanes; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carrageenan;

2018
Anti-inflammatory effects of nesfatin-1 on acetic acid-induced gastric ulcer in rats: involvement of cyclo-oxygenase pathway.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2017, Volume: 68, Issue:5

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Calcium-Binding Proteins; Cyclooxygenase 1; Cyclooxy

2017
Oil from the fruits of Pterodon emarginatus Vog.: A traditional anti-inflammatory. Study combining in vivo and in silico.
    Journal of ethnopharmacology, 2018, Aug-10, Volume: 222

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Croton Oil; Cyclooxygenase

2018
Synthesis and biological properties of aryl methyl sulfones.
    Bioorganic & medicinal chemistry, 2018, 08-07, Volume: 26, Issue:14

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carrageenan; Dimet

2018
[Study on Variation of Gastroprotective Effect of Atractylodes lancea Rhizome Before and After Processing].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2016, Volume: 39, Issue:4

    Topics: Acetic Acid; Animals; Atractylodes; Drugs, Chinese Herbal; Rats; Rhizome; Stomach Ulcer; Trefoil Fac

2016
Sex-specific effects of
    World journal of gastroenterology, 2018, Oct-14, Volume: 24, Issue:38

    Topics: Acetic Acid; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Eugenia; Female; Gastric

2018
Chemical characterization and evaluation of gastric antiulcer properties of the hydroethanolic extract of the stem bark of Virola elongata (Benth.) Warb.
    Journal of ethnopharmacology, 2019, Mar-01, Volume: 231

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Ethanol; Female; Mice; Myristicaceae; Phytochemicals; Phyto

2019
BST-104, a Water Extract of Lonicera japonica, Has a Gastroprotective Effect via Antioxidant and Anti-Inflammatory Activities.
    Journal of medicinal food, 2019, Volume: 22, Issue:2

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Chlorogenic Acid; C

2019
Bmi1 marks gastric stem cells located in the isthmus in mice.
    The Journal of pathology, 2019, Volume: 248, Issue:2

    Topics: Acetic Acid; Animals; Biomarkers; Cell Differentiation; Cell Lineage; Cell Proliferation; Disease Mo

2019
(-)-Myrtenol accelerates healing of acetic acid-induced gastric ulcers in rats and in human gastric adenocarcinoma cells.
    European journal of pharmacology, 2019, Jul-05, Volume: 854

    Topics: Acetic Acid; Adenocarcinoma; Animals; Bicyclic Monoterpenes; Cell Line, Tumor; Cell Movement; Cell P

2019
Evaluation of the antiulcer activity of the aqueous stem bark extract of Balanites aegyptiaca L Delile in Wistar rats.
    Journal of ethnopharmacology, 2019, Jul-15, Volume: 239

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Balanites; Ethanol; Indomethacin; Ligation; Male; Phytother

2019
Hesperidin, a citrus flavanone glycoside, accelerates the gastric healing process of acetic acid-induced ulcer in rats.
    Chemico-biological interactions, 2019, Aug-01, Volume: 308

    Topics: Acetic Acid; Animals; Catalase; Drug Administration Schedule; Flavanones; Gastric Mucosa; Glutathion

2019
Antiulcer activity of Cyperus alternifolius in relation to its UPLC-MS metabolite fingerprint: A mechanistic study.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 62

    Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Chromatography, Liquid;

2019
Protective effect of polysaccharides from Radix Hedysari on gastric ulcers induced by acetic acid in rats.
    Food & function, 2019, Jul-17, Volume: 10, Issue:7

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Cell Movement; Cell

2019
The probiotic mixture VSL#3 accelerates gastric ulcer healing by stimulating vascular endothelial growth factor.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Acetic Acid; Animals; Cytokines; DNA Primers; Dose-Response Relationship, Drug; Gene Expression Regu

2013
Role of gastric mucus secretion, oxinitrergic system and sulfhydryl groups on the gastroprotection elicited by Polygala cyparissias (Polygalaceae) in mice.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:5

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Chronic Disease; Ethanol; Gastric Mucosa; Helicobacter pylo

2013
[Study on efficacy and mechanism of weiyangning pills against experimental gastric ulcer].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:5

    Topics: Acetic Acid; Animals; Aspirin; Dinoprostone; Drugs, Chinese Herbal; Epidermal Growth Factor; Female;

2013
Arbortristoside-A and 7-O-trans-cinnamoyl-6β-hydroxyloganin isolated from Nyctanthes arbortristis possess anti-ulcerogenic and ulcer-healing properties.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Sep-15, Volume: 20, Issue:12

    Topics: Acetic Acid; Alcohols; Animals; Anti-Ulcer Agents; Cinnamates; Disease Models, Animal; Female; Irido

2013
Desvenlafaxine succinate ameliorates visceral hypersensitivity but delays solid gastric emptying in rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2013, Aug-15, Volume: 305, Issue:4

    Topics: Acetic Acid; Administration, Oral; Adrenergic Uptake Inhibitors; Animals; Cyclohexanols; Desvenlafax

2013
NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4(+)VEGFR1(+) cells to the ulcer granulation tissues.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2013, Volume: 67, Issue:7

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemokine CXCL12; Enzyme Pre

2013
Zinc(II)-curcumin accelerates the healing of acetic acid-induced chronic gastric ulcers in rats by decreasing oxidative stress and downregulation of matrix metalloproteinase-9.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 60

    Topics: Acetic Acid; Animals; Curcumin; Disease Models, Animal; Down-Regulation; Gastric Mucosa; Glutathione

2013
The acid-secreting parietal cell as an endocrine source of Sonic Hedgehog during gastric repair.
    Endocrinology, 2013, Volume: 154, Issue:12

    Topics: Acetic Acid; Animals; Cell Line; Epithelial Cells; Female; Gastric Mucosa; Gene Expression Regulatio

2013
High-mobility group box 1 inhibits gastric ulcer healing through Toll-like receptor 4 and receptor for advanced glycation end products.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Acetic Acid; Animals; Antibodies; Gastric Mucosa; Gene Expression Regulation; Glycation End Products

2013
Experimental healing of preexisting gastric ulcers induced by hormones controlling food intake ghrelin, orexin-A and nesfatin-1 is impaired under diabetic conditions. A key to understanding the diabetic gastropathy?
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2013, Volume: 64, Issue:5

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Calcium-Binding Proteins; Diabetes Mellitus, Experimental;

2013
Estrogen alleviates acetic acid-induced gastric or colonic damage via both ERα- and ERβ-mediated and direct antioxidant mechanisms in rats.
    Inflammation, 2014, Volume: 37, Issue:3

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Movement; Colitis; Cytokines; Est

2014
Evaluation of the gastroprotective activity of the extracts, fractions, and pure compounds obtained from aerial parts of Rubus imperialis in different experimental models.
    Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:4

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Ethanol; Indometha

2014
Rhamnogalacturonan from Acmella oleracea (L.) R.K. Jansen: gastroprotective and ulcer healing properties in rats.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Asteraceae; Body Weight; Cell Proliferation;

2014
Metabolomics coupled with multivariate data and pathway analysis on potential biomarkers in gastric ulcer and intervention effects of Corydalis yanhusuo alkaloid.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Acetic Acid; Alkaloids; Animals; Base Sequence; Biomarkers; Chromatography, High Pressure Liquid; Co

2014
Evaluation of the morphological changes of gastric mucosa induced by a low concentration of acetic acid using a rat model.
    Journal of forensic and legal medicine, 2014, Volume: 22

    Topics: Acetic Acid; Animals; Burns, Chemical; Caustics; Fibroblasts; Forensic Pathology; Gastric Mucosa; Ma

2014
Motility and chemotaxis mediate the preferential colonization of gastric injury sites by Helicobacter pylori.
    PLoS pathogens, 2014, Volume: 10, Issue:7

    Topics: Acetic Acid; Animals; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Indicators and R

2014
Mechanisms involved in the gastroprotective activity of Celtis iguanaea (Jacq.) Sargent on gastric lesions in mice.
    Journal of ethnopharmacology, 2014, Sep-29, Volume: 155, Issue:3

    Topics: Acetic Acid; Adrenergic alpha-2 Receptor Antagonists; Animals; Anti-Ulcer Agents; Cyclooxygenase Inh

2014
Synthesis, hydrolysis kinetics and pharmacological evaluation of aceclofenac prodrugs.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2015, Volume: 13, Issue:3

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal;

2015
Antiulcerogenic activity of Carica papaya seed in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2015, Volume: 388, Issue:3

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carica; Ethanol; F

2015
Terminalia catappa L.: a medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models.
    Journal of ethnopharmacology, 2015, Jan-15, Volume: 159

    Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Caribbean Region; Disease Models, An

2015
Comparison of the anti-ulcer activity between the crude and bran-processed Atractylodes lancea in the rat model of gastric ulcer induced by acetic acid.
    Journal of ethnopharmacology, 2015, Feb-03, Volume: 160

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Atractylodes; Dietary Fiber; Dinoprostone; Disease M

2015
Evidence of gastric ulcer healing activity of Maytenus robusta Reissek: In vitro and in vivo studies.
    Journal of ethnopharmacology, 2015, Dec-04, Volume: 175

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Brazil; Catalase; Cell Line, Tumor; Cell Survival; Female;

2015
Evaluation of the safety, gastroprotective activity and mechanism of action of standardised leaves infusion extract of Copaifera malmei Harms.
    Journal of ethnopharmacology, 2015, Dec-04, Volume: 175

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Brazil; Catalase; Cell Survival; CHO Cells; Cricetulus; Eth

2015
Gastroprotective effects of thymol on acute and chronic ulcers in rats: The role of prostaglandins, ATP-sensitive K(+) channels, and gastric mucus secretion.
    Chemico-biological interactions, 2016, Jan-25, Volume: 244

    Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relation

2016
Healing mechanisms of the hydroalcoholic extract and ethyl acetate fraction of green tea (Camellia sinensis (L.) Kuntze) on chronic gastric ulcers.
    Naunyn-Schmiedeberg's archives of pharmacology, 2016, Volume: 389, Issue:3

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Camellia sinensis; Ethanol; Female; Gastric Acid;

2016
Gastroprotective potential of Pentahydroxy flavone isolated from Madhuca indica J. F. Gmel. leaves against acetic acid-induced ulcer in rats: The role of oxido-inflammatory and prostaglandins markers.
    Journal of ethnopharmacology, 2016, Apr-22, Volume: 182

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Biomarkers; Cyclooxygenase 2; Gastric Mucosa; Glutathione;

2016
Protective Effect of Cod (Gadus macrocephalus) Skin Collagen Peptides on Acetic Acid-Induced Gastric Ulcer in Rats.
    Journal of food science, 2016, Volume: 81, Issue:7

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Collagen; Gadiformes; Gastric Mucosa; HSP70 H

2016
Glyprolines exert protective and repair-promoting effects in the rat stomach: potential role of the cytokine GRO/CINC-1.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2016, Volume: 67, Issue:2

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cells, Cultured; Chemokine CXCL1; Epithelial Cells; Gastric

2016
Diminazene aceturate, an angiotensin-converting enzyme II activator, prevents gastric mucosal damage in mice: Role of the angiotensin-(1-7)/Mas receptor axis.
    Biochemical pharmacology, 2016, 07-15, Volume: 112

    Topics: Acetic Acid; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, An

2016
Hydroethanolic extract of Baccharis trimera promotes gastroprotection and healing of acute and chronic gastric ulcers induced by ethanol and acetic acid.
    Naunyn-Schmiedeberg's archives of pharmacology, 2016, Volume: 389, Issue:9

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Baccharis; Cytoprotection; Disease Models, An

2016
Rational Design and Synthesis of Biologically Active Disubstituted 2(3H) Furanones and Pyrrolone Derivatives as Potent and Safer Non Steroidal Anti-inflammatory Agents.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2016, Volume: 15, Issue:1

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Female; Furans; Male

2016
Piper umbellatum L.: A medicinal plant with gastric-ulcer protective and ulcer healing effects in experimental rodent models.
    Journal of ethnopharmacology, 2016, Nov-04, Volume: 192

    Topics: Acetic Acid; Acute Disease; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Catalase; Chronic Dis

2016
Beta-cyclodextrin enhanced gastroprotective effect of (-)-linalool, a monoterpene present in rosewood essential oil, in gastric lesion models.
    Naunyn-Schmiedeberg's archives of pharmacology, 2016, Volume: 389, Issue:11

    Topics: Acetic Acid; Acyclic Monoterpenes; Animals; Anti-Ulcer Agents; Antioxidants; beta-Cyclodextrins; Cyt

2016
The direct comparison of health and ulcerated stomach tissue: a multiple probe microdialysis sampling approach.
    Journal of pharmaceutical and biomedical analysis, 2008, Sep-10, Volume: 48, Issue:1

    Topics: Acetic Acid; Animals; Area Under Curve; Caffeine; Calibration; Chromatography, High Pressure Liquid;

2008
Characterization of eltenac and novel COX-2 selective thiopheneacetic acid analogues in vitro and in vivo.
    Biochemical pharmacology, 2008, Sep-15, Volume: 76, Issue:6

    Topics: Acetic Acid; Aniline Compounds; Animals; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibit

2008
Acetic acid induced ulceration in rats is not affected by infection with Hymenolepis diminuta.
    The Journal of parasitology, 2009, Volume: 95, Issue:2

    Topics: Acetic Acid; Animals; Disease Models, Animal; Hymenolepiasis; Hymenolepis diminuta; Male; Rats; Rats

2009
The role of sensory C-fibers in response of vagal afferent stimulation by gastric distension in rats with experimental chronic gastric ulcer.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59 Suppl 2

    Topics: Acetic Acid; Afferent Pathways; Animals; Capsaicin; Chronic Disease; Disease Models, Animal; Gastric

2008
Effects of pantoprazole on ulcer healing delay associated with NSAID treatment.
    Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 379, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroid

2009
Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol.
    European journal of pharmacology, 2008, Dec-28, Volume: 601, Issue:1-3

    Topics: Acetic Acid; Administration, Oral; Aging; alpha-Tocopherol; Animals; Anti-Ulcer Agents; Antioxidants

2008
Synthesis, analgesic and anti inflammatory activities of some new fenamate analogues.
    Arzneimittel-Forschung, 2008, Volume: 58, Issue:9

    Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry,

2008
Synthesis and evaluation of antiinflammatory and analgesic activities of a novel series of coumarin Mannich bases.
    Arzneimittel-Forschung, 2008, Volume: 58, Issue:10

    Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Coumarins; Drug Evaluation

2008
Alpha-lipoic acid improves acetic acid-induced gastric ulcer healing in rats.
    Inflammation, 2009, Volume: 32, Issue:1

    Topics: Acetic Acid; Animals; Antioxidants; DNA Fragmentation; Female; Gastric Mucosa; Glutathione; Luminesc

2009
Cytokine signalling by gp130 regulates gastric mucosal healing after ulceration and, indirectly, antral tumour progression.
    The Journal of pathology, 2009, Volume: 217, Issue:4

    Topics: Acetic Acid; Animals; Cell Proliferation; Cytokine Receptor gp130; Disease Progression; Fibrosis; Ga

2009
Synergy between enzyme inhibitors of fatty acid amide hydrolase and cyclooxygenase in visceral nociception.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:1

    Topics: Acetic Acid; Amidohydrolases; Animals; Benzamides; Carbamates; Cyclooxygenase Inhibitors; Diclofenac

2009
Novel 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines: synthesis, characterization, and evaluation of analgesic/anti-inflammatory, antioxidant activities.
    Archiv der Pharmazie, 2009, Volume: 342, Issue:5

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carrageenan

2009
Treatment with ghrelin accelerates the healing of acetic acid-induced gastric and duodenal ulcers in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009, Volume: 60, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cell Proliferation; Chronic Disease; DNA; Dose-Response Rel

2009
Protective and therapeutic effects of resveratrol on acetic acid-induced gastric ulcer.
    Free radical research, 2009, Volume: 43, Issue:6

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Female; Glutathione; Irritants; Lipid

2009
Gastroprotective constituents of Salvia officinalis L.
    Fitoterapia, 2009, Volume: 80, Issue:7

    Topics: Abietanes; Acetic Acid; Animals; Anti-Ulcer Agents; Ethanol; Female; Gastric Mucosa; Phytotherapy; P

2009
In vitro and in vivo anti-Helicobacter pylori activity of Calophyllum brasiliense Camb.
    Journal of ethnopharmacology, 2009, Jun-25, Volume: 123, Issue:3

    Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Brazil; Calophyllum; Dinoprostone; D

2009
Synthesis of novel 1,3,4-oxadiazole derivatives and their biological properties.
    Acta pharmaceutica (Zagreb, Croatia), 2009, Volume: 59, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Carrageenan; Dise

2009
[Therapeutic effect of astaxanthin on acetic acid-induced gastric ulcer in rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2009, Volume: 44, Issue:5

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Catalase; Gastric Mucosa; Glutathione Peroxid

2009
Effect of methanolic extract of Pongamia pinnata Linn seed on gastro-duodenal ulceration and mucosal offensive and defensive factors in rats.
    Indian journal of experimental biology, 2009, Volume: 47, Issue:8

    Topics: Acetic Acid; Animals; Aspirin; Catalase; Chromatography, Thin Layer; Cold Temperature; Duodenal Ulce

2009
Role of modulation of vascular endothelial growth factor and tumor necrosis factor-alpha in gastric ulcer healing in diabetic rats.
    Biochemical pharmacology, 2010, Jun-01, Volume: 79, Issue:11

    Topics: Acetic Acid; Animals; Anticholesteremic Agents; Diabetes Mellitus, Experimental; Free Radical Scaven

2010
[Influence of honey, royal jelly and propolis on accelerating acetate healing of experimental gastric ulcers in rats].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2009, Issue:6

    Topics: Acetic Acid; Animals; Anti-Infective Agents; Chronic Disease; Disease Models, Animal; Fatty Acids; H

2009
Synthesis of new 2,3-dihydroquinazolin-4(1H)-one derivatives for analgesic and anti-inflammatory evaluation.
    Archiv der Pharmazie, 2010, Volume: 343, Issue:5

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Chalcones; Drug Evaluation,

2010
Effects of lansoprazole on the expression of VEGF and cellular proliferation in a rat model of acetic acid-induced gastric ulcer.
    Journal of gastroenterology, 2010, Volume: 45, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Anti-Ulcer Agents; Cell Cycle; Cell P

2010
Enhancement of gastric ulcer healing and angiogenesis by cochinchina Momordica seed extract in rats.
    Journal of Korean medical science, 2010, Volume: 25, Issue:6

    Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Factor VIII; Male; Momordica; Neovasc

2010
Altered expression of a putative progenitor cell marker DCAMKL1 in the rat gastric mucosa in regeneration, metaplasia and dysplasia.
    BMC gastroenterology, 2010, Jun-18, Volume: 10

    Topics: Acetic Acid; Animals; Biomarkers; Cell Proliferation; Disease Models, Animal; Doublecortin Protein;

2010
Role of microsomal prostaglandin E synthase-1 in the facilitation of angiogenesis and the healing of gastric ulcers.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 299, Issue:5

    Topics: Acetic Acid; Analysis of Variance; Animals; Cyclooxygenase 2; Gastric Mucosa; Immunoenzyme Technique

2010
Yogurt containing Lactobacillus gasseri OLL 2716 (LG21 yogurt) accelerated the healing of acetic acid-induced gastric ulcer in rats.
    Bioscience, biotechnology, and biochemistry, 2010, Volume: 74, Issue:9

    Topics: Acetic Acid; Animals; Dinoprostone; Gamma Rays; Gastric Mucosa; Hydrochloric Acid; Lactobacillus; Pr

2010
[Investigation of therapeutic mechanism of Weiweifang on experimental gastric ulcer in rats viewing from metabonomics].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2010, Volume: 30, Issue:10

    Topics: Acetic Acid; Amino Acids; Animals; Drugs, Chinese Herbal; Fatty Acids; Gas Chromatography-Mass Spect

2010
Ginger extract and polaprezinc exert gastroprotective actions by anti-oxidant and growth factor modulating effects in rats.
    Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:12

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Carnosine; Chemokines; Cytokines; Cytoprotect

2010
Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats.
    Journal of ethnopharmacology, 2011, Mar-24, Volume: 134, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Biomarkers; Cisapride; Disease Models

2011
Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae).
    Journal of ethnopharmacology, 2011, Apr-26, Volume: 135, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Bicyclic Monoterpenes; Brazil; Bridged Bicyclo Compounds; C

2011
Design and synthesis of certain mesoionic sydnonyl styrylketones as potential nonsteroidal antiinflammatory agents.
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:3

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Drug Design; Edema; Fema

2011
Gastroprotective and ulcer-healing mechanisms of ellagic acid in experimental rats.
    Journal of agricultural and food chemistry, 2011, Jul-13, Volume: 59, Issue:13

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cytokines; Dinoprostone; Ellagic Acid; Ethanol; Female; Gas

2011
Fluorine bearing sydnones with styryl ketone group: synthesis and their possible analgesic and anti-inflammatory activities.
    Journal of enzyme inhibition and medicinal chemistry, 2012, Volume: 27, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Croton Oil; Edema; Female;

2012
Stimulation of gastric ulcer healing by heat shock protein 70.
    Biochemical pharmacology, 2011, Oct-01, Volume: 82, Issue:7

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; HSP70 Heat-Shock Proteins; Male; Mice; Mice, Inbred C57BL;

2011
Pharmacological profile of FK881(ASP6537), a novel potent and selective cyclooxygenase-1 inhibitor.
    Biochemical pharmacology, 2011, Oct-01, Volume: 82, Issue:7

    Topics: Acetic Acid; Animals; Arthritis, Experimental; Carrageenan; CHO Cells; Cricetinae; Cricetulus; Cyclo

2011
Activity of DBXX granules on anti-gastric ulcer and decreasing the side effect of chemotherapy in S180 tumor-bearing mice.
    Journal of ethnopharmacology, 2011, Oct-11, Volume: 137, Issue:3

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antineoplastic Agents; Cyclophosphamide; Dose-Response Rela

2011
Role of activation of 5'-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats.
    Pharmacology, 2011, Volume: 88, Issue:5-6

    Topics: Acetic Acid; Animals; Blood Glucose; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Experi

2011
Mechanisms of action underlying the gastric antiulcer activity of the Rhizophora mangle L.
    Journal of ethnopharmacology, 2012, Jan-06, Volume: 139, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Epidermal

2012
Isolation of active constituents from cherry laurel (Laurocerasus officinalis Roem.) leaves through bioassay-guided procedures.
    Journal of ethnopharmacology, 2012, Jan-31, Volume: 139, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Biological Assay; Capilla

2012
Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model.
    Journal of gastroenterology and hepatology, 2012, Volume: 27 Suppl 3

    Topics: Acetic Acid; Adenocarcinoma; Administration, Topical; Animals; Antineoplastic Agents; Disease Models

2012
Antiulcerogenic effect of Croton urucurana Baillon bark.
    Journal of ethnopharmacology, 2012, Aug-30, Volume: 143, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Croton; Disease Models, Animal; Ethanol; Female; Gastric Ac

2012
Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:2

    Topics: 1-Deoxynojirimycin; Acetic Acid; Animals; Apoptosis; Disease Models, Animal; Enzyme Inhibitors; Fumo

2013
Antiulcer effect of bark extract of Tabebuia avellanedae: activation of cell proliferation in gastric mucosa during the healing process.
    Phytotherapy research : PTR, 2013, Volume: 27, Issue:7

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cell Proliferation; Female; Gastric Mucosa; Mucus; Phenols;

2013
Ethanolic extract of roots from Arctium lappa L. accelerates the healing of acetic acid-induced gastric ulcer in rats: Involvement of the antioxidant system.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 51

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Arctium; Capillary Permeability; Ethanol; Fem

2013
Evaluation of antiulcer activity and mechanism of action of methanol stem bark extract of Lafoensia pacari A. St.-Hil. (Lytraceae) in experimental animals.
    Journal of ethnopharmacology, 2012, Dec-18, Volume: 144, Issue:3

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Brazil; Ethanol; Gastrointestinal Transit; Indomethacin; In

2012
[Effect of Pongamia pinnata root flavonoids on the quality of ulcer healing and expression of EGF and TGF-alpha in the rat model of gastric ulcer induced by acetic acid].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2012, Volume: 28, Issue:5

    Topics: Acetic Acid; Animals; Epidermal Growth Factor; Female; Flavonoids; Gastric Mucosa; Male; Millettia;

2012
Evaluation of the analgesic and anti-inflammatory activities of some thiazolo[4,5-d]pyrimidines.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:6

    Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan

2002
[Deficit of glucocorticoid production in rats aggravates ulcerogenic effects of stimuli of various modality and intensity].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2002, Volume: 88, Issue:5

    Topics: Acetic Acid; Adrenalectomy; Animals; Aspirin; Corticosterone; Ethanol; Glucocorticoids; Hormone Repl

2002
Mechanism of the antiulcerogenic effect of IL-11 on acetic acid-induced gastric ulcer in rats.
    Life sciences, 2002, May-10, Volume: 70, Issue:25

    Topics: Acetic Acid; Animals; Humans; Interleukin-11; Male; Proliferating Cell Nuclear Antigen; Rats; Rats,

2002
Rebamipide prevents delay of acetic acid-induced gastric ulcer healing caused by Helicobacter pylori infection in Mongolian gerbils.
    Digestive diseases and sciences, 2002, Volume: 47, Issue:7

    Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Apoptosis; Cell Division; Epithelium; Gerbillinae;

2002
Models of gastric hyperalgesia in the rat.
    American journal of physiology. Gastrointestinal and liver physiology, 2002, Volume: 283, Issue:3

    Topics: Acetic Acid; Animals; Avoidance Learning; Behavior, Animal; Catheterization; Disease Models, Animal;

2002
Oligoethylene ester derivatives of ketoprofen, naproxen and diclofenac as oral prodrugs: a pharmacological evaluation.
    Die Pharmazie, 2002, Volume: 57, Issue:8

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Edema; Ester

2002
Antinociceptive and gastroprotective effects of diterpenes from the flower buds of Egletes viscosa.
    Planta medica, 2002, Volume: 68, Issue:11

    Topics: Acetic Acid; Analgesics; Animals; Anti-Ulcer Agents; Asteraceae; Diterpenes; Dose-Response Relations

2002
Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor.
    Scandinavian journal of gastroenterology, 2003, Volume: 38, Issue:2

    Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Cyclooxygenase 2; Gastric Mucosa; Glyceraldehyde-3

2003
Effects of hydrochloric, acetic, butyric, and propionic acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses.
    American journal of veterinary research, 2003, Volume: 64, Issue:4

    Topics: Acetic Acid; Animals; Butyric Acid; Culture Techniques; Fatty Acids, Volatile; Female; Gastric Mucos

2003
Synthesis of ibuprofen heterocyclic amides and investigation of their analgesic and toxicological properties.
    European journal of medicinal chemistry, 2003, Volume: 38, Issue:5

    Topics: Acetic Acid; Administration, Oral; Amides; Analgesics, Non-Narcotic; Animals; Ibuprofen; Injections,

2003
Nerve growth factor and gastric hyperalgesia in the rat.
    Neurogastroenterology and motility, 2003, Volume: 15, Issue:4

    Topics: Acetic Acid; Animals; Antibodies; Electromyography; Enzyme-Linked Immunosorbent Assay; Hyperalgesia;

2003
Oleanolic acid promotes healing of acetic acid-induced chronic gastric lesions in rats.
    Pharmacological research, 2003, Volume: 48, Issue:3

    Topics: Acetic Acid; Analysis of Variance; Animals; Gastric Mucosa; Histamine H2 Antagonists; Male; Oleanoli

2003
Rebamipide binds to iNOS-positive cells in acetic acid-treated but not in ethanol-treated rat gastric mucosa.
    Alimentary pharmacology & therapeutics, 2003, Volume: 18 Suppl 1

    Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Binding Sites; Ethanol; Gastric Mucosa; Indicators

2003
Transforming growth factor-alpha directly augments histidine decarboxylase and vesicular monoamine transporter 2 production in rat enterochromaffin-like cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 286, Issue:3

    Topics: Acetic Acid; Animals; Blotting, Northern; Cell Separation; Cells, Cultured; Enterochromaffin Cells;

2004
Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2003, Volume: 54, Issue:3

    Topics: Acetic Acid; Animals; Dinoprostone; Disease Models, Animal; Drug Administration Schedule; Fibrosis;

2003
Temporal increase in the gastric colonization of Helicobacter pylori after healing of acetic acid-induced gastric ulcer in a miniature pig.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2003, Volume: 36, Issue:3

    Topics: Acetic Acid; Animals; Colony Count, Microbial; Helicobacter Infections; Helicobacter pylori; Male; S

2003
Gastroprotective and anti-inflammatory effects of resin from Protium heptaphyllum in mice and rats.
    Pharmacological research, 2004, Volume: 49, Issue:2

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Brazil; Burseraceae; Capillary Pe

2004
Roles of inducible nitric oxide synthase in the development and healing of experimentally induced gastric ulcers.
    International journal of experimental pathology, 2003, Volume: 84, Issue:5

    Topics: Acetic Acid; Animals; Apoptosis; Cell Division; Gene Expression; Male; Mice; Mice, Inbred C57BL; Neo

2003
[Deficiency of glucocorticoid production delays the healing of acute gastric mucosal erosion and chronic ulcers in rats].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2003, Volume: 89, Issue:9

    Topics: Acetic Acid; Adrenalectomy; Animals; Chronic Disease; Corticosterone; Gastric Mucosa; Glucocorticoid

2003
Estradiol treatment ameliorates acetic acid-induced gastric and colonic injuries in rats.
    Inflammation, 2003, Volume: 27, Issue:6

    Topics: Acetic Acid; Animals; Colitis; Dose-Response Relationship, Drug; Epithelium; Estradiol; Female; Male

2003
Synthesis, characterization and antiinflammatory-analgesic properties of 6-(alpha-amino-4-chlorobenzyl)thiazolo [3,2-b]-1,2,4-triazol-5-ols.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:1

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoquinones; Capillary Per

2004
The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats.
    Life sciences, 2004, Mar-19, Volume: 74, Issue:18

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cell Division; Centella; Chromatography, High Pressure Liqu

2004
Role of brain-gut axis in healing of gastric ulcers.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2004, Volume: 55, Issue:1 Pt 2

    Topics: Acetic Acid; Animals; Brain; Capsaicin; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Gastri

2004
Mucosal irritative and healing impairment action of risedronate in rat stomachs: comparison with alendronate.
    Journal of gastroenterology and hepatology, 2004, Volume: 19, Issue:5

    Topics: Acetic Acid; Alendronate; Animals; Diphosphonates; Etidronic Acid; Gastric Mucosa; Male; Rats; Rats,

2004
Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:4

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Aspirin; Azadirachta; Bacopa; Cold Temperature; Diabetes Me

2004
Antiulcer activity of Utleria salicifolia rhizome extract.
    Journal of ethnopharmacology, 2004, Volume: 91, Issue:2-3

    Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Dose-Response

2004
Serum response factor is a critical requirement for VEGF signaling in endothelial cells and VEGF-induced angiogenesis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:11

    Topics: Acetic Acid; Actins; Animals; Cell Division; Cell Movement; Cells, Cultured; Collagen; Culture Media

2004
Evaluation of Pongamia pinnata root extract on gastric ulcers and mucosal offensive and defensive factors in rats.
    Indian journal of experimental biology, 2003, Volume: 41, Issue:4

    Topics: Acetic Acid; Animals; Anti-Infective Agents, Local; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ul

2003
[Effect of Chinese drugs for jianpi huayu on healing quality of gastric ulcer in rats].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2004, Volume: 24, Issue:7

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Drugs, Chinese Herbal; Epidermal Growth Factor; ErbB Recept

2004
Experimentally induced ulcers and gastric sensory-motor function in rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 288, Issue:2

    Topics: Acetic Acid; Animals; Gastrointestinal Motility; Male; Muscle Contraction; Muscle, Smooth; Pain; Phy

2005
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
    Life sciences, 2004, Nov-26, Volume: 76, Issue:2

    Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani

2004
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
    Life sciences, 2004, Nov-26, Volume: 76, Issue:2

    Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani

2004
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
    Life sciences, 2004, Nov-26, Volume: 76, Issue:2

    Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani

2004
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
    Life sciences, 2004, Nov-26, Volume: 76, Issue:2

    Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani

2004
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
    Life sciences, 2004, Nov-26, Volume: 76, Issue:2

    Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani

2004
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
    Life sciences, 2004, Nov-26, Volume: 76, Issue:2

    Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani

2004
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
    Life sciences, 2004, Nov-26, Volume: 76, Issue:2

    Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani

2004
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
    Life sciences, 2004, Nov-26, Volume: 76, Issue:2

    Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani

2004
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
    Life sciences, 2004, Nov-26, Volume: 76, Issue:2

    Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani

2004
[Protective effect of the intraperitoneal and intragastric administration of PGP-peptide on ethanol-induced erosions and acetate-induced ulcers in rats].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2004, Issue:4

    Topics: Acetic Acid; Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug

2004
Synthesis, biological evaluation and kinetic studies of glyceride prodrugs of diclofenac.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:11

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Chromatography, High Pressu

2004
COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions.
    International immunopharmacology, 2005, Volume: 5, Issue:2

    Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxyge

2005
A new property of endogenous immunostimulator Taftsin.
    Bulletin of experimental biology and medicine, 2004, Volume: 138, Issue:2

    Topics: Acetic Acid; Adjuvants, Immunologic; Animals; Ethanol; Male; Rats; Restraint, Physical; Stomach Ulce

2004
Ganoderma lucidum polysaccharide fractions accelerate healing of acetic acid-induced ulcers in rats.
    Journal of medicinal food, 2004,Winter, Volume: 7, Issue:4

    Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Disease Models, Animal; Dose-Response

2004
Gastric ulcers evoke hyperexcitability and enhance P2X receptor function in rat gastric sensory neurons.
    Journal of neurophysiology, 2005, Volume: 93, Issue:6

    Topics: Acetic Acid; Adenosine Triphosphate; Animals; Carbocyanines; Cells, Cultured; Dose-Response Relation

2005
Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes.
    Journal of gastroenterology and hepatology, 2005, Volume: 20, Issue:2

    Topics: Acetic Acid; Animals; Colitis; Darkness; Ethanol; Female; Gastric Mucosa; Inflammation; Intestinal M

2005
Is gastric ulceration different in normal and malnourished rats?
    The British journal of nutrition, 2005, Volume: 93, Issue:1

    Topics: Acetic Acid; Animals; Body Weight; Corticosterone; Cytoprotection; Dinoprostone; Ethanol; Female; Ga

2005
Administration of L-arginine reduces the delay of the healing process caused by ibuprofen. Implication of COX and growth factors expression.
    Histology and histopathology, 2005, Volume: 20, Issue:2

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Chronic Disease; Cyclooxyge

2005
Therapeutic effect of D-002 (abexol) on gastric ulcer induced experimentally in rats.
    Journal of medicinal food, 2005,Spring, Volume: 8, Issue:1

    Topics: Acetic Acid; Acute Disease; Administration, Oral; Animals; Anti-Ulcer Agents; Antioxidants; Chronic

2005
Anti-inflammatory, antinociceptive, and gastric effects of Hypericum perforatum in rats.
    TheScientificWorldJournal, 2005, Aug-08, Volume: 5

    Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin;

2005
Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils.
    Digestive diseases and sciences, 2005, Volume: 50 Suppl 1

    Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Free Radicals; Gastric Mucosa; Glutathione Peroxid

2005
[Expression and activity of cyclooxygenases-1 and -2 in acetic acid induced gastric ulcer in rats].
    Zhonghua yi xue za zhi, 2001, Dec-25, Volume: 81, Issue:24

    Topics: Acetic Acid; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Isoenzymes; Male; Rats; Rats, Sprague-Dawl

2001
Cell proliferation in the gastric epithelium of the ulcer rat.
    Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:12

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Epithelial Cells;

2005
Gastroprotective and ulcer healing effect of ferruginol in mice and rats: assessment of its mechanism of action using in vitro models.
    Life sciences, 2006, Apr-18, Volume: 78, Issue:21

    Topics: Abietanes; Acetic Acid; Animals; Anti-Ulcer Agents; Biphenyl Compounds; Cell Line; Cell Survival; Di

2006
Gaultherin, a natural salicylate derivative from Gaultheria yunnanensis: towards a better non-steroidal anti-inflammatory drug.
    European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

    Topics: Abdominal Pain; Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal;

2006
Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats.
    World journal of gastroenterology, 2005, Dec-07, Volume: 11, Issue:45

    Topics: 6-Ketoprostaglandin F1 alpha; Acetic Acid; Animals; Chlorpheniramine; Chronic Disease; Drug Synergis

2005
[Study of the effect of exceed critical extracts from Radix Aucklandiae on experimental gastric ulcer model].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2005, Volume: 28, Issue:11

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Disease Models, Animal; Drugs, Chinese Herbal; Gastric Muco

2005
Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats.
    Autonomic neuroscience : basic & clinical, 2006, Jun-30, Volume: 126-127

    Topics: Acetic Acid; Adrenal Glands; Animals; Anti-Inflammatory Agents, Non-Steroidal; Consciousness; Cortic

2006
Differential effects of selective and non-selective inhibition of nitric oxide synthase on the expression and activity of cyclooxygenase-2 during gastric ulcer healing.
    European journal of pharmacology, 2006, May-01, Volume: 536, Issue:3

    Topics: Acetic Acid; Amidines; Animals; Benzylamines; Blotting, Western; Cyclooxygenase 2; Enzyme Inhibitors

2006
The cationic host defense peptide rCRAMP promotes gastric ulcer healing in rats.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:2

    Topics: Acetic Acid; Actins; Animals; Anti-Ulcer Agents; Antimicrobial Cationic Peptides; Blotting, Western;

2006
Analgesic, antiinflammatory, and ulcerogenic studies of meloxicam solid dispersion prepared with polyethylene glycol 6000.
    Methods and findings in experimental and clinical pharmacology, 2006, Volume: 28, Issue:7

    Topics: Abdominal Pain; Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal;

2006
Evaluation of anti-inflammatory and analgesic activity of a new class of biphenyl analogs in animal models of inflammation.
    Arzneimittel-Forschung, 2006, Volume: 56, Issue:9

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; C-Rea

2006
Anti-ulcer effect of tea catechin in rats.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:11

    Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Camellia sinensis; Catechin; Dose-Res

2006
[Effects of jianwei yuyang granule on inflammatory reaction and NF-kappaB expression in rat gastric mucosa of ulcer healing and recurrence].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:17

    Topics: Acetic Acid; Animals; Drug Combinations; Drugs, Chinese Herbal; Female; Gastric Mucosa; Male; NF-kap

2006
Luminal stimuli acutely sensitize visceromotor responses to distension of the rat stomach.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:2

    Topics: Acetic Acid; Afferent Pathways; Animals; Catheterization; Disease Models, Animal; Dyspepsia; Electro

2007
[Effect of mucosal protective on the quality of gastric ulcer healing].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2007, Volume: 36, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Diterpenes; Drug Therapy, Combination; ErbB Receptors; Gast

2007
Synthesis of 3-[4'-(p-chlorophenyl)-thiazol-2'-yl]-2-[(substituted azetidinone/thiazolidinone)-aminomethyl]-6-bromoquinazolin-4-ones as anti-inflammatory agent.
    Bioorganic & medicinal chemistry, 2007, Apr-15, Volume: 15, Issue:8

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azetidines; Dose-Response Relationshi

2007
2-Amino/azido/hydrazino-5-alkoxy-5H-[1]benzopyrano[4,3-d]pyrimidines: synthesis and pharmacological evaluation.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2007, Volume: 3, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Carragee

2007
Gastroprotective effects of DA-6034, a new flavonoid derivative, in various gastric mucosal damage models.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:11

    Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Centra

2007
Impairment of gastric ulcer healing by alendronate, a nitrogen-containing bisphosphonate, in rats.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:8

    Topics: Acetic Acid; Alendronate; Animals; Bone Density Conservation Agents; Cells, Cultured; Cyclooxygenase

2007
Effect of peroxisome proliferator-activated receptor-alpha agonist (bezafibrate) on gastric secretion and gastric cytoprotection in rats.
    Fundamental & clinical pharmacology, 2007, Volume: 21, Issue:3

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Bezafibrate; Ethanol; Gastric Acid; Gastric Mucosa; Indomet

2007
Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2007, Volume: 20, Issue:1-4

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Base Sequence; Cyclooxygenas

2007
Antinociceptive and anti-inflammatory steroidal saponins from Dracaena ombet.
    Planta medica, 2007, Volume: 73, Issue:10

    Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Dose-

2007
Hydrogen sulfide enhances ulcer healing in rats.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2007, Volume: 21, Issue:14

    Topics: Acetic Acid; Animals; Hydrogen Sulfide; Intubation, Gastrointestinal; Male; Organothiophosphorus Com

2007
[Somatic pain sensitivity of conscious rats with chronic gastric ulcers].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2007, Volume: 93, Issue:4

    Topics: Acetic Acid; Animals; Male; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Stomach Ul

2007
Flavonoid-rich fraction of Maytenus ilicifolia Mart. ex. Reiss protects the gastric mucosa of rodents through inhibition of both H+,K+ -ATPase activity and formation of nitric oxide.
    Journal of ethnopharmacology, 2007, Sep-25, Volume: 113, Issue:3

    Topics: Acetic Acid; Animals; Female; Flavonoids; Gastric Acid; Gastric Juice; Gastric Mucosa; Glutathione;

2007
Prophylactic effect of rebamipide against the irritative and healing impairment actions of alendronate in rat stomachs.
    Inflammopharmacology, 2007, Volume: 15, Issue:5

    Topics: Acetic Acid; Administration, Oral; Alanine; Alendronate; Animals; Anti-Ulcer Agents; Blotting, Weste

2007
Effect of dopamine on the healing of acetic acid-induced gastric ulcers in rats.
    Inflammopharmacology, 2007, Volume: 15, Issue:5

    Topics: Acetic Acid; Animals; Dopamine; Gastric Mucosa; Gene Expression; Male; Rats; Rats, Sprague-Dawley; R

2007
Selank and its metabolites maintain homeostasis in the gastric mucosa.
    Bulletin of experimental biology and medicine, 2007, Volume: 143, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Ethanol; Gastric Mucosa; Homeostasis; Male; Oligopeptides;

2007
Studies of gastric mucosa regeneration and safety promoted by Mouriri pusa treatment in acetic acid ulcer model.
    Journal of ethnopharmacology, 2008, Jan-17, Volume: 115, Issue:2

    Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Cell Proliferation; Gastric Mucosa; M

2008
Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis.
    Gastroenterology, 2008, Volume: 134, Issue:1

    Topics: Acetic Acid; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Ethanol; G

2008
New celecoxib derivatives as anti-inflammatory agents.
    Journal of medicinal chemistry, 2008, Jan-10, Volume: 51, Issue:1

    Topics: Acetic Acid; Animals; Carrageenan; Celecoxib; Chronic Disease; Crystallization; Cyclooxygenase 1; Cy

2008
Synthesis and biological evaluation of thieno[2,3-d]pyrimidine derivatives for anti-inflammatory, analgesic and ulcerogenic activity.
    Acta pharmaceutica (Zagreb, Croatia), 2007, Volume: 57, Issue:4

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Disease Models, An

2007
Ketorolac-dextran conjugates: synthesis, in vitro and in vivo evaluation.
    Acta pharmaceutica (Zagreb, Croatia), 2007, Volume: 57, Issue:4

    Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Buffers; Carrag

2007
Cultured bone marrow cell local implantation accelerates healing of ulcers in mice.
    Journal of gastroenterology, 2008, Volume: 43, Issue:2

    Topics: Acetic Acid; Animals; Bone Marrow Transplantation; Cell Transdifferentiation; Cells, Cultured; Femal

2008
Histomorphological characteristics of accelerated healing of acetate ulcers under the effect of glyprolines.
    Bulletin of experimental biology and medicine, 2007, Volume: 144, Issue:2

    Topics: Acetic Acid; Animals; Gastric Mucosa; Male; Oligopeptides; Proline; Rats; Regeneration; Stomach Ulce

2007
Synthesis and pharmacological evaluation of 2-substituted benzo[b]thiophenes as anti-inflammatory and analgesic agents.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Acetic Acid; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; C

2009
Effect of 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy) chalcone (sofalcone) on chronic gastric ulcers in rats.
    Japanese journal of pharmacology, 1984, Volume: 35, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cell Division; Chalcone; Chalcones; Gastric Mucos

1984
Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Female; Gastric Acid; Gastric Mucosa;

1984
[Experimental studies on gastric ulcer (6). Endoscopical evaluation of healing processes of acetic acid ulcer in rats (2): Healing, recurrence and relapse of ulcer].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1984, Volume: 83, Issue:1

    Topics: Acetates; Acetic Acid; Age Factors; Animals; Female; Gastric Mucosa; Gastroscopy; Male; Rats; Recurr

1984
Changes in synthetic activity of sulfated mucosubstances in healing process of acetic acid ulcer in rats and effect of anti-ulcer agents.
    Japanese journal of pharmacology, 1984, Volume: 34, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Gastric Mucosa; Male; Rats; Rats, Inbred Strains;

1984
Experimental studies on gastric ulcer. (4). Sequential observation and evaluation of gastric ulcers by endoscope in the rat.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Gastroscopy; Rats; Rats, Inbred Strains; Stomach Ulcer

1983
Exacerbation of acetic acid ulcer induced by non-steroidal anti-inflammatory drugs in rats.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents; Aspirin; Gastric Emptying; Gastric Juice;

1983
[Studies on defensive factors of experimental ulcers (2). Increasing action of aceglutamide aluminum on defensive factors in acetic acid ulcers of rats (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:4

    Topics: Acetates; Acetic Acid; Administration, Oral; Aluminum; Animals; Anti-Ulcer Agents; Gastric Mucosa; G

1982
[Experimental study for the gastric mucosal damage--especially, the effect of cigarette smoking on the healing course of acetic acid ulcer in rats (author's transl)].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1981, Dec-01, Volume: 78, Issue:12

    Topics: Acetates; Acetic Acid; Animals; Male; Nicotine; Rats; Rats, Inbred Strains; Smoking; Stomach Ulcer;

1981
Effect of basic fibroblast growth factor on microvascular regeneration from gastric ulcerative lesion-increased binding site of bFGF after CS23 treatment.
    Microvascular research, 1995, Volume: 50, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Binding Sites; Fibroblast Growth Factor 2; Granulation Tissue; Micro

1995
Changes in gastric function and healing of chronic gastric ulcers in aged rats.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:1

    Topics: Acetates; Acetic Acid; Aging; Animals; Cell Division; Gastric Acid; Gastrins; Gastrointestinal Motil

1995
Influence of ammonia solution on gastric mucosa and acetic acid induced ulcer in rats.
    European journal of histochemistry : EJH, 1994, Volume: 38, Issue:1

    Topics: Acetates; Acetic Acid; Ammonia; Animals; Bromodeoxyuridine; Cell Division; DNA; Dose-Response Relati

1994
Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:9

    Topics: Acetates; Acetic Acid; Allopurinol; Animals; Cyclooxygenase Inhibitors; Dimethyl Sulfoxide; Free Rad

1995
Gene expression of keratinocyte and hepatocyte growth factors during the healing of rat gastric mucosal lesions.
    Gastroenterology, 1995, Volume: 109, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Base Sequence; Cell Line; Cells, Cultured; DNA; Fibroblast Growth Fa

1995
Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:11

    Topics: Acetates; Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Cimetidine; Drug Therapy, Combination; M

1995
Plasticity of myofibroblasts appearing in granulation tissues after acetic acid treatment. Effect of bFGF.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:11

    Topics: Acetates; Acetic Acid; Animals; Autoradiography; Desmin; Fibroblast Growth Factor 2; Fibroblasts; Ga

1995
Misoprostol reverses the inhibition of gastric hyperemia and aggravation of gastric damage by tobacco cigarette smoke in the rat.
    Scandinavian journal of gastroenterology, 1995, Volume: 30, Issue:4

    Topics: Acetates; Acetic Acid; Analysis of Variance; Animals; Gastric Mucosa; Hyperemia; Male; Misoprostol;

1995
Antiulcer action and toxicity of Styrax camporum and Caesalpinia ferrea.
    Planta medica, 1995, Volume: 61, Issue:3

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Female; Gastric Acid; Gastric Mucosa; Plant Extra

1995
Enhancement in gastric mucosal EGF and PDGF receptor expression with ulcer healing by sulglycotide.
    General pharmacology, 1995, Volume: 26, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cell Membrane; Chronic Disease; ErbB Receptors; G

1995
Wound healing of acetic acid-induced gastric ulcer in rats and the effects of cimetidine and calcitonin, with special reference to prolylhydroxylase and collagenase enzyme activity.
    Journal of gastroenterology, 1995, Volume: 30, Issue:3

    Topics: Acetates; Acetic Acid; Animals; Calcitonin; Cells, Cultured; Cimetidine; Collagenases; Gastric Mucos

1995
Inhibition of nitric oxide synthase delays healing of chronic gastric ulcers.
    European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3

    Topics: Acetates; Acetic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Gastric Mucosa; Male; Nitric O

1993
Two phenotypically distinct B lymphocytes (IgMhighIgDlow and IgMlowIgDhigh) in chronic gastric ulcer in the rat.
    Clinical and experimental immunology, 1995, Volume: 100, Issue:1

    Topics: Acetates; Acetic Acid; Animals; B-Lymphocyte Subsets; Chronic Disease; Fluorescent Antibody Techniqu

1995
[Therapeutic effect of IGN-2098, a new antiulcer drug (H2-antagonist), in the ulcer diminishing period against acetic acid-induced gastric ulcer in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1995, Volume: 105, Issue:3

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Famotidine; Histamine H2 Antagonists; Male; Piper

1995
Acceleration of healing of gastric ulcers induced in rats by liquid diet: importance of tissue contraction.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:4

    Topics: Acetates; Acetic Acid; Animal Feed; Animals; Body Weight; Cell Division; Cellulose; Food, Formulated

1994
Anti-inflammatory effects of etodolac: comparison with other non-steroidal anti-inflammatory drugs.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:12

    Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Ca

1994
Zinc deficiency delays gastric ulcer healing in rats.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:6

    Topics: Acetates; Acetic Acid; Animals; Bromodeoxyuridine; Cell Division; Diet; Disease Models, Animal; Gast

1995
Tobacco cigarette smoke aggravates gastric ulcer in rats by attenuation of ulcer margin hyperemia.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 1

    Topics: Acetates; Acetic Acid; Animals; Hyperemia; Injections, Subcutaneous; Male; Nicotiana; Nicotine; Plan

1995
Effect of cimetidine and omeprazole on gastric ulcer healing of rats with limited food intake time.
    European journal of pharmacology, 1994, Oct-03, Volume: 263, Issue:3

    Topics: Acetates; Acetic Acid; Administration, Oral; Analysis of Variance; Animals; Atropine; Cimetidine; Di

1994
Validity of kissing gastric ulcers induced in rats for screening of antiulcer drugs.
    Journal of gastroenterology and hepatology, 1994, Volume: 9 Suppl 1

    Topics: Acetates; Acetic Acid; Aluminum Hydroxide; Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; D

1994
Cell proliferation kinetics in acetic acid-induced gastric ulcer evaluated by immunohistochemical staining of proliferating cell nuclear antigen.
    Journal of clinical gastroenterology, 1993, Volume: 17 Suppl 1

    Topics: Acetates; Acetic Acid; Animals; Cell Division; Gastric Mucosa; Immunoenzyme Techniques; Male; Nuclea

1993
Influence of capsaicin-sensitive afferent fibers on acetic acid-induced chronic gastric ulcers in rats.
    Scandinavian journal of gastroenterology, 1994, Volume: 29, Issue:5

    Topics: Acetates; Acetic Acid; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Chronic Disease; Male; N

1994
Persistent lack of somatostatin receptors in gastric mucosa of healing ulcers in rats.
    Gastroenterology, 1994, Volume: 107, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Autoradiography; Cicatrix; ErbB Receptors; Female; Gastric Mucosa; R

1994
Effects of misoprostol on delayed ulcer healing induced by aspirin.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:5

    Topics: Acetates; Acetic Acid; Animals; Aspirin; Gastric Mucosa; Male; Misoprostol; Rats; Rats, Inbred Strai

1994
3,3'-Bi-[1,3-thiazolidine-4-one] system. VII. Synthesis and SARS of some 2-heteroaryl derivatives with antiinflammatory and related activities.
    Farmaco (Societa chimica italiana : 1989), 1994, Volume: 49, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Ca

1994
Biochemical and pharmacological properties of a newly synthesized proton pump (H+/K(+)-ATPase) inhibitor, TY-11345 in experimental animals.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Benzimidazoles; Duodenal Ulcer; Epirizole; Ethano

1993
Protective action of vinpocetine against experimentally induced gastric damage in rats.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:9

    Topics: Acetates; Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Dinoprostone; Ethanol; Fema

1993
Enhancement in gastric mucosal laminin receptor expression with ulcer healing.
    Biochemistry and molecular biology international, 1993, Volume: 31, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Gastric Mucosa; Laminin; Male; Radioligand Assay; Rats; Rats, Spragu

1993
Apoptosis: genetically programmed physiologic cell loss in normal gastric oxyntic mucosa and in mucosa of grossly healed gastric ulcer.
    Journal of clinical gastroenterology, 1993, Volume: 17 Suppl 1

    Topics: Acetates; Acetic Acid; Animals; Apoptosis; Epithelium; Gastric Mucosa; Male; Microscopy, Electron; O

1993
[The pharmacodynamics of troxipide on experimental gastric ulcers in rats].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1993, Volume: 24, Issue:3

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Female; Male; Piperidines; Rats; Rats

1993
Evaluation of acetic acid-induced gastric ulcers in dogs by endoscopic ultrasonography.
    Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:12

    Topics: Acetates; Acetic Acid; Animals; Dogs; Gastroscopy; Predictive Value of Tests; Sensitivity and Specif

1993
[Anti-ulcer effect of the drug OF-743 in an acid model of ulcer formation by the Okabe method].
    Nauchnye doklady vysshei shkoly. Biologicheskie nauki, 1993, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Disease Models, Animal; Gastric Mucosa; Male; Pep

1993
Effect of NC-1300-O-3 on healing of acetic acid-induced gastric ulcers in rats.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Benzimid

1993
Fibroblast growth factor in gastroprotection and ulcer healing: interaction with sucralfate.
    Gut, 1993, Volume: 34, Issue:7

    Topics: Acetates; Acetic Acid; Acute Disease; Animals; Aspirin; Disease Models, Animal; Dose-Response Relati

1993
Effect and mechanism of sucralfate on healing of acetic acid-induced gastric ulcers in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1993, Volume: 44, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Dinoprostone; Gastric Mucosa; Indomethacin; Male; Rats; Rats, Inbred

1993
Mechanism by which indomethacin delays gastric ulcer healing in the rat: inhibited contraction of the ulcer base.
    Japanese journal of pharmacology, 1993, Volume: 61, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Connective Tissue; Gastric Mucosa; Indomethacin; Male; Muscle Contra

1993
Effects of indomethacin and prednisolone on the different stages of healing of acetic acid-induced gastric ulcers in the rat.
    Japanese journal of pharmacology, 1993, Volume: 61, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Collagen; Connective Tissue; Gastric Mucosa; Indomethacin; Male; Pre

1993
Increase in mucosal and connective tissue-type mast cells in the stomach with acetic acid-induced ulcer in rat.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 1996, Volume: 104, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Cell Count; Connective Tissue; Gastric Mucosa; Male; Mast Cells; Rat

1996
Anti-inflammatory and analgesic activity of Baccharis trimera: identification of its active constituents.
    Planta medica, 1996, Volume: 62, Issue:3

    Topics: Acetates; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanols; Carra

1996
[A study on factors of acupuncture methods affecting effects through acupuncture treatments for experimental gastric ulcer in rats].
    Zhen ci yan jiu = Acupuncture research, 1995, Volume: 20, Issue:2

    Topics: Acetates; Acetic Acid; Acupuncture Therapy; Animals; Electroacupuncture; Female; Lipid Peroxides; Ma

1995
[Influence of KU-1257 on the recurrence and relapse of acetic acid-induced chronic gastric ulcers in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1996, Volume: 107, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Chronic Disease; Cimetidine; Histamine H2 Antagonists; Male; Phenylu

1996
Role of polymorphonuclear leukocytes and oxygen-derived free radicals in chronic gastric lesion induced by acetic acid in rat.
    General pharmacology, 1996, Volume: 27, Issue:3

    Topics: Acetic Acid; Allopurinol; Animals; Antimetabolites; Capillary Permeability; Enzyme Inhibitors; Epith

1996
Influence of age on natural and delayed healing of experimentally-induced gastric ulcers in rats.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:9

    Topics: Acetates; Acetic Acid; Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Indomethacin; Male;

1996
Simultaneous evaluation of gastric and duodenal ulcers-healing activities of anti-ulcer agents in rats.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Atropine; Chronic Disease; Cimetidine; Duodenal Ulcer; Hist

1996
Synchronized induction in bFGF and Cdk2 during gastric ulcer healing.
    Biochemistry and molecular biology international, 1996, Volume: 40, Issue:2

    Topics: Acetic Acid; Animals; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Fibro

1996
Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat.
    Gut, 1996, Volume: 38, Issue:6

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Capsaicin; Chronic Disease; Cimetidine; Drug Therapy, Combi

1996
Helicobacter pylori infection delays the healing of acetic acid-induced gastric ulcer in Japanese monkeys.
    Journal of gastroenterology and hepatology, 1996, Volume: 11, Issue:11

    Topics: Acetic Acid; Animals; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Macaca; Stomach

1996
Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice.
    Gastroenterology, 1997, Volume: 112, Issue:2

    Topics: Acetic Acid; Acids; Animals; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2

1997
Simultaneous restitution of matrix and cells in gastric ulcer: use of a combined in-situ hybridization and immunohistochemistry technique applicable to paraffin-embedded tissue.
    Cell and tissue research, 1997, Volume: 287, Issue:3

    Topics: Acetic Acid; Animals; Collagen; Digoxigenin; Extracellular Matrix; Immunohistochemistry; In Situ Hyb

1997
Role of neutrophils in a rat model of gastric ulcer recurrence caused by interleukin-1 beta.
    The American journal of pathology, 1997, Volume: 150, Issue:3

    Topics: Acetic Acid; Animals; Antibodies, Monoclonal; Cell Count; Endoscopy; Gastric Mucosa; Humans; Injecti

1997
Investigations on the protective action of Condonopsis pilosula (Dangshen) extract on experimentally-induced gastric ulcer in rats.
    General pharmacology, 1997, Volume: 28, Issue:3

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Drugs, Chinese Herbal; Duodenum; Gastric Acid; Gastric Muco

1997
Increased expression of transforming growth factor-beta1 during gastric ulcer healing in rats.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:3

    Topics: Acetic Acid; Alprostadil; Animals; Blotting, Northern; Extracellular Matrix Proteins; Gastric Mucosa

1997
Prevention of gastric ulcer relapse induced by indomethacin in rats by a mutein of basic fibroblast growth factor.
    Japanese journal of pharmacology, 1997, Volume: 73, Issue:3

    Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agen

1997
Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats.
    Scandinavian journal of gastroenterology, 1997, Volume: 32, Issue:5

    Topics: Acetic Acid; Animals; Collagenases; Connective Tissue; Disease Models, Animal; Gastric Mucosa; Gelat

1997
Inoculation of VacA- and CagA- Helicobacter pylori delays gastric ulcer healing in the rat.
    Scandinavian journal of gastroenterology, 1997, Volume: 32, Issue:5

    Topics: Acetic Acid; Animals; Antigens, Bacterial; Apoptosis; Bacterial Proteins; Cell Division; Disease Mod

1997
ME-3407, a new antiulcer agent, inhibits acid secretion by interfering with redistribution of H(+)-K(+)-ATPase.
    The American journal of physiology, 1997, Volume: 272, Issue:5 Pt 1

    Topics: Acetic Acid; Androstadienes; Animals; Anti-Ulcer Agents; Cyclic AMP-Dependent Protein Kinases; Enzym

1997
Pharmacological profile of the novel potent antirheumatic 4-(2',4'-difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic acid.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:5

    Topics: Abdominal Pain; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Art

1997
Changes in sulfated macromolecules produced in vivo during normal and indomethacin-delayed ulcer healing in rats.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:8

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Gastric Mucosa; Glycosaminoglycans; G

1997
Pepsinogen C gene product is a possible growth factor during gastric mucosal healing.
    Biochemical and biophysical research communications, 1997, Sep-08, Volume: 238, Issue:1

    Topics: Acetic Acid; Animals; DNA, Complementary; Gastric Mucosa; Gastritis; Gene Expression Regulation; Gro

1997
Gastric ulcer healing in the rat: kinetics and localisation of de novo procollagen synthesis.
    Gut, 1997, Volume: 41, Issue:2

    Topics: Acetic Acid; Animals; Extracellular Matrix; Gastric Mucosa; Gene Expression; Immunohistochemistry; I

1997
The potentiating actions of cigarette smoking on ethanol-induced gastric mucosal damage in rats.
    Gastroenterology, 1997, Volume: 113, Issue:4

    Topics: Acetic Acid; Animals; Cold Temperature; Dinoprostone; Ethanol; Gastric Mucosa; Leukotriene C4; Male;

1997
Kinetics of fibroblasts in ulcer healing in rats: interference with indomethacin.
    Digestion, 1997, Volume: 58, Issue:4

    Topics: Acetic Acid; Actins; Animals; Apoptosis; Culture Techniques; Cyclooxygenase Inhibitors; Disease Mode

1997
Kinetics and collagenolytic role of eosinophils in chronic gastric ulcer in the rat.
    Histochemistry and cell biology, 1997, Volume: 108, Issue:1

    Topics: Acetic Acid; Animals; Antibodies, Monoclonal; Antibody Specificity; Chronic Disease; Collagenases; E

1997
Relationship between healing of acetic acid-induced chronic gastric ulcer and connexin.
    Journal of clinical gastroenterology, 1997, Volume: 25 Suppl 1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Chronic Disease; Cimetidine; Connexins; Epidermal Growth Fa

1997
Basic fibroblast growth factor increases constitutive nitric oxide synthase during healing of rat gastric ulcers.
    Journal of clinical gastroenterology, 1997, Volume: 25 Suppl 1

    Topics: Acetic Acid; Animals; Enzyme Inhibitors; Fibroblast Growth Factor 2; Gastric Mucosa; Humans; Male; N

1997
Mechanistic study of adverse actions of cigarette smoke exposure on acetic acid-induced gastric ulceration in rats.
    Life sciences, 1998, Volume: 62, Issue:3

    Topics: Acetic Acid; Allopurinol; Animals; Dinoprostone; Enzyme Activation; Gastric Mucosa; Male; Nicotiana;

1998
Phosphatidylcholine-associated aspirin accelerates healing of gastric ulcers in rats.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:4

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Combinations; Male; Pho

1998
[Effect of lafutidine, a novel antiulcer agent, on healing and relapse of acetic acid-induced gastric ulcer in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1998, Volume: 111, Issue:3

    Topics: Acetamides; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Dose-Response Relationship, Drug; F

1998
Mechanism by which indomethacin delays the healing of acetic acid-induced ulcers in rats. Role of neutrophil antichemotactic and chemotactic activities.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1998, Volume: 49, Issue:1

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemotactic Factors; Dinoprostone; Ga

1998
Bacteria rapidly colonize and modulate healing of gastric ulcers in rats.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Bacitracin; Escherichia coli; Gastric Acid; Lactobacill

1998
Anti-ulcer effects of antioxidants: effect of probucol.
    European journal of pharmacology, 1998, Aug-07, Volume: 354, Issue:2-3

    Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Antioxidants; Chronic Disease; Cimetidine; D

1998
Effects of novel anti-inflammatory compounds on healing of acetic acid-induced gastric ulcer in rats.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:1

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; C

1998
Localization of cyclooxygenase-2 and regulation of its mRNA expression in gastric ulcers in rats.
    The American journal of physiology, 1998, Volume: 275, Issue:5

    Topics: Acetic Acid; Animals; Antibodies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhi

1998
Anti-ulcer effects of antioxidants, quercetin, alpha-tocopherol, nifedipine and tetracycline in rats.
    Japanese journal of pharmacology, 1998, Volume: 78, Issue:4

    Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Antioxidants; Calcium Channel Blocke

1998
Relationship between vascular endothelial growth factor and angiogenesis in spontaneous and indomethacin-delayed healing of acetic acid-induced gastric ulcers in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1998, Volume: 49, Issue:4

    Topics: Acetic Acid; Animals; Cyclooxygenase Inhibitors; Endothelial Growth Factors; Gastric Mucosa; Indomet

1998
Midkine gene expression in the healing process of gastric ulcer.
    The Journal of laboratory and clinical medicine, 1999, Volume: 133, Issue:4

    Topics: Acetic Acid; Animals; Carrier Proteins; Cell Division; Cell Line; Cytokines; Fibroblasts; Gastric Mu

1999
Healing effects of heparin on acetic acid-induced gastric ulcers in rats.
    Chinese medical journal, 1998, Volume: 111, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Dinoprostone; Dose-Response Relationship, Drug; Gastric Muc

1998
Local downregulation of enterochromaffin-like cell histamine formation in ulcer healing: a study in rats.
    Digestion, 1999, Volume: 60, Issue:3

    Topics: Acetic Acid; Animals; Chromogranin A; Chromogranins; Down-Regulation; Enterochromaffin-like Cells; F

1999
A new ulcer model, "unhealed gastric ulcers", induced by chronic treatment with indomethacin in rats with acetic acid ulcers.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1999, Volume: 50, Issue:2

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cyclooxygenase Inh

1999
Delayed healing of acetic-acid-induced gastric ulcer in portal hypertensive rats.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1999, Volume: 31, Issue:4

    Topics: Acetic Acid; Animals; Cell Division; Disease Models, Animal; Gastric Mucosa; Hypertension, Portal; L

1999
Regulation by endogenous interleukin-1 of mRNA expression of healing-related factors in gastric ulcers in rats.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Acetic Acid; Animals; Cells, Cultured; Chemotaxis; Dinoprostone; Dose-Response Relationship, Drug; G

1999
Gastrointestinal absorption of a new reversible proton pump inhibitor, YJA-20379-8, and its pharmacokinetics after oral administration in acetic acid-induced gastric ulcer in rats.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:9

    Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Area Under Curve; Chromatography, Hig

1999
Distribution of Helicobacter pylori in a Mongolian gerbil gastric ulcer model.
    Laboratory animal science, 1999, Volume: 49, Issue:6

    Topics: Acetic Acid; Animals; Colony Count, Microbial; Disease Models, Animal; Gastric Mucosa; Gerbillinae;

1999
Effect of recombinant human basic fibroblast growth factor on stomach ulcers in rats and mice.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:8

    Topics: Acetic Acid; Animals; DNA; Female; Fibroblast Growth Factor 2; Gastric Mucosa; Ligation; Male; Mice;

1999
Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing.
    Digestion, 2000, Volume: 61, Issue:3

    Topics: Acetic Acid; Analysis of Variance; Animals; Hematologic Agents; Immunoenzyme Techniques; Male; Neutr

2000
Autonomic nervous regeneration in acetic acid-induced ulcer from the viewpoint of synapse formation--effect of basic fibroblast growth factor and sofalcone in the rat.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14 Suppl 1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Autonomic Nervous System; Autoradiography; Binding Sites; C

2000
The effects of water extracts of CagA positive or negative Helicobacter pylori on proliferation, apoptosis and connexin formation in acetic acid-induced gastric ulcer of rats.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14 Suppl 1

    Topics: Acetic Acid; Animals; Antigens, Bacterial; Apoptosis; Bacterial Proteins; Blotting, Western; Cell Di

2000
Synthesis and pharmacological screening of 1,3,4-thiadiazino[2,3-b]quinazoline derivatives.
    Die Pharmazie, 2000, Volume: 55, Issue:10

    Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, A

2000
Effect of oligofucose derivatives on acetic acid-induced gastric ulcer in rats.
    Bio-medical materials and engineering, 2001, Volume: 11, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Male;

2001
Expression of a specific mucin type recognized by monoclonal antibodies in the rat gastric mucosa regenerating from acetic acid-induced ulcer.
    Scandinavian journal of gastroenterology, 2001, Volume: 36, Issue:5

    Topics: Acetic Acid; Animals; Antibodies, Monoclonal; Disease Models, Animal; Gastric Mucins; Gastric Mucosa

2001
Expression of decorin and biglycan in rat gastric tissue: effects of ulceration and basic fibroblast growth factor.
    Scandinavian journal of gastroenterology, 2001, Volume: 36, Issue:7

    Topics: Acetic Acid; Animals; Apoptosis; Biglycan; Decorin; Disease Models, Animal; Drug Evaluation, Preclin

2001
Effect of centrally administered prolactin on gastric and duodenal ulcers in rats.
    Fundamental & clinical pharmacology, 2001, Volume: 15, Issue:3

    Topics: Acetic Acid; Animals; Chronic Disease; Cysteamine; Duodenal Ulcer; Ethanol; Gastric Acid; Gastric Ac

2001
The antiulcerative effect of Thai Musa species in rats.
    Phytotherapy research : PTR, 2001, Volume: 15, Issue:5

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Female; Indomethacin; Pla

2001
Macrophage migration inhibitory factor is an important mediator in the pathogenesis of gastric inflammation in rats.
    Gastroenterology, 2001, Volume: 121, Issue:3

    Topics: Acetic Acid; Acute Disease; Animals; Antibodies, Monoclonal; Disease Models, Animal; Gastritis; Gene

2001
Effect of jianpiyiqi prescription on the expression of heat shock proteins in acetic acid-induced chronic gastric ulcer rats.
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 2001, Volume: 21, Issue:2

    Topics: Acetic Acid; Animals; Chronic Disease; Drugs, Chinese Herbal; Heat-Shock Proteins; Male; Phytotherap

2001
Effect of hyperprolactinaemia as induced by pituitary homografts under kidney capsule on gastric and duodenal ulcers in rats.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:11

    Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Cysteamine; Duodenal Ulcer; Gastric Acid; Hype

2001
Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs.
    Life sciences, 2001, Nov-21, Volume: 70, Issue:1

    Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Chronic Disease; Cysteamine; Disease Models,

2001
Prophylactic and curative effects of Bacopa monniera in gastric ulcer models.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2001, Volume: 8, Issue:6

    Topics: Acetic Acid; Animals; Antioxidants; Aspirin; Catalase; Cell Division; Cold Temperature; Disease Mode

2001
Experimental ulcers alter voltage-sensitive sodium currents in rat gastric sensory neurons.
    Gastroenterology, 2002, Volume: 122, Issue:2

    Topics: Acetic Acid; Anesthetics, Local; Animals; Disease Models, Animal; Ganglia, Spinal; Gastritis; Hypera

2002
Effect of butanol fraction of Panax ginseng head on gastric lesion and ulcer.
    Archives of pharmacal research, 2002, Volume: 25, Issue:1

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Butanols; Gast

2002
[Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats].
    Zhonghua yi xue za zhi, 2001, Nov-25, Volume: 81, Issue:22

    Topics: Acetic Acid; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dino

2001
Transient increase of rat gastric amylin in the neonatal period and in experimental ulcers.
    Journal of gastroenterology, 2002, Volume: 37, Issue:3

    Topics: Acetic Acid; Amyloid; Animals; Animals, Newborn; Gastric Mucosa; Indicators and Reagents; Islet Amyl

2002
Time-course changes of ECL cell markers in acetic acid-induced gastric ulcers in rats.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16 Suppl 2

    Topics: Acetic Acid; Animals; Biomarkers; Blotting, Northern; Down-Regulation; Enterochromaffin-like Cells;

2002
Influence of Helicobacter pylori infection on healing and relapse of acetic acid ulcers in Mongolian gerbils.
    Digestive diseases and sciences, 2002, Volume: 47, Issue:4

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cyclooxygenase Inh

2002
Acidic fibroblast growth factor accelerates the healing of acetic-acid-induced gastric ulcers in rats.
    Digestion, 1992, Volume: 53, Issue:1-2

    Topics: Acetates; Acetic Acid; Aluminum Hydroxide; Animals; Antacids; Drug Combinations; Famotidine; Female;

1992
[Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50, Issue:1

    Topics: Acetates; Acetic Acid; Adenosine Triphosphatases; Animals; Chronic Disease; Drug Therapy, Combinatio

1992
[Therapeutic effect of moxibustion on experimental gastric ulcer of rats and its mechanism].
    Zhen ci yan jiu = Acupuncture research, 1992, Volume: 17, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Dinoprost; Dinoprostone; Female; Gastric Mucosa; Male; Moxibustion;

1992
Gastroprotective and ulcer-healing activities of a new H2-receptor antagonist: ebrotidine.
    Digestion, 1992, Volume: 51, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Benzenesulfonates; Epidermal Growth Factor; Ethanol; Gastric Acid; G

1992
[The antigastroulcerative activity of beta-sitosterol-beta-D-glucoside and its aglycone in rats].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1992, Volume: 23, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Female; Male; Rats; Rats, Inbred Strains; Sitoste

1992
[The immunohistochemical study on the recurrent mechanism of acetic acid induced gastric ulcer in rats--extracellular matrix and cellular kinetics].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1992, Volume: 89, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Cell Cycle; Epithelium; Extracellular Matrix; Fibronectins; Gastric

1992
[The gastric mucosal adhesiveness of Z-103 in rats with chronic ulcer].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 99, Issue:4

    Topics: Acetates; Acetic Acid; Adhesiveness; Animals; Anti-Ulcer Agents; Carnosine; Chronic Disease; Dipepti

1992
Effects of H2-receptor antagonists on matrix metalloproteinases in rat gastric tissues with acetic acid-induced ulcer.
    Journal of pharmacobio-dynamics, 1991, Volume: 14, Issue:6

    Topics: Acetates; Acetic Acid; Animals; Extracellular Matrix; Gelatin; Histamine H2 Antagonists; Male; Metal

1991
Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats.
    Digestion, 1990, Volume: 47, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Cimetidine; Dose-Response Relationship, Drug; Granulation Tissue; Ma

1990
Helicobacter pylori affects the quality of experimental gastric ulcer healing in a new animal model.
    Experimental and molecular pathology, 1991, Volume: 55, Issue:3

    Topics: Acetates; Acetic Acid; Animals; Disease Models, Animal; Gastric Mucosa; Helicobacter pylori; Male; R

1991
Research on heterocyclic compounds. XXVIII. Imidazo[1,2-c]pyrimidines.
    Farmaco (Societa chimica italiana : 1989), 1991, Volume: 46, Issue:10

    Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bridged Bicyclo Compounds;

1991
Evaluation of acetic acid-induced gastric ulcers in rats by scanning acoustic microscopy.
    Scandinavian journal of gastroenterology, 1991, Volume: 26, Issue:3

    Topics: Acetates; Acetic Acid; Acoustics; Animals; Disease Models, Animal; Male; Microscopy; Rats; Rats, Inb

1991
Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat.
    The American journal of medicine, 1991, Aug-08, Volume: 91, Issue:2A

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidi

1991
Effects of the new anti-ulcer agent 12-sulfodehydroabietic acid monosodium salt on healing of acetic acid-induced gastric ulcers in rats.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:5

    Topics: Abietanes; Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Carbenoxolone; Diterpenes; Gastric Muc

1991
Effects of prostaglandins on hydrocortisone-induced delayed healing of chronic gastric ulcers in the rat.
    Journal of clinical gastroenterology, 1991, Volume: 13 Suppl 1

    Topics: 16,16-Dimethylprostaglandin E2; Acetates; Acetic Acid; Animals; Epoprostenol; Gastric Mucosa; Hydroc

1991
Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats.
    Gastroenterology, 1991, Volume: 100, Issue:5 Pt 1

    Topics: Acetates; Acetic Acid; Animals; Dinoprostone; Gastric Mucosa; Indomethacin; Male; Omeprazole; Rats;

1991
Healing of acetic acid-induced gastric ulcer and gastric mucosal PGI2 level in rats.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Epoprostenol; Gastric Mucosa; Male; Rats; Rats, Inbred Strains; Recu

1990
Roles of muscularis mucosae and myofibroblasts in the healing process of acetic acid-induced ulcer.
    Journal of clinical gastroenterology, 1990, Volume: 12 Suppl 1

    Topics: Acetates; Acetic Acid; Animals; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Gastri

1990
"Healed" experimental gastric ulcers remain histologically and ultrastructurally abnormal.
    Journal of clinical gastroenterology, 1990, Volume: 12 Suppl 1

    Topics: Acetates; Acetic Acid; Animals; Gastric Mucosa; Male; Microscopy, Electron; Rats; Rats, Inbred Strai

1990
Vascular and microvascular changes--key factors in the development of acetic acid-induced gastric ulcers in rats.
    Journal of clinical gastroenterology, 1990, Volume: 12 Suppl 1

    Topics: Acetates; Acetic Acid; Animals; Gastric Mucosa; Granulation Tissue; Male; Microcirculation; Microsco

1990
Effect of epidermal growth factor in combination with sucralfate or omeprazole on the healing of chronic gastric ulcers in the rat.
    Journal of clinical gastroenterology, 1990, Volume: 12 Suppl 1

    Topics: Acetates; Acetic Acid; Animals; Drug Therapy, Combination; Epidermal Growth Factor; Male; Omeprazole

1990
Effect of omeprazole on delayed healing of acetic acid-induced gastric ulcers in rats.
    Japanese journal of pharmacology, 1990, Volume: 54, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Drug Therapy, Combination; Gastric Acid; Histamine; Indomethacin; Ma

1990
Efficacy of combined ranitidine and pentacaine treatment in experimentally induced gastric damage in rats.
    Agents and actions, 1990, Volume: 30, Issue:1-2

    Topics: Acetates; Acetic Acid; Anesthetics, Local; Animals; Carbamates; Drug Therapy, Combination; Female; P

1990
Effect of zinc acexamate and ranitidine on chronic gastric lesions in the rat.
    Digestion, 1990, Volume: 45, Issue:3

    Topics: Acetates; Acetic Acid; Aminocaproates; Aminocaproic Acid; Animals; Anti-Ulcer Agents; Male; Ranitidi

1990
Effects of prednisolone and human epidermal growth factor on angiogenesis in granulation tissue of gastric ulcer induced by acetic acid.
    Digestion, 1989, Volume: 42, Issue:3

    Topics: Acetates; Acetic Acid; Animals; Drug Combinations; Epidermal Growth Factor; Granulation Tissue; Male

1989
Physiological significance of mucous neck cell-type mucins in the healing of acetic acid-induced gastric ulcers in rats.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: Acetates; Acetic Acid; Animals; Gastric Mucosa; Male; Mucins; Rats; Rats, Inbred Strains; Staining a

1989
Nociceptive sensitivity/behavioral reactivity regulation in rats during aversive states of different nature: its mediation by opioid peptides.
    The International journal of neuroscience, 1989, Volume: 44, Issue:1-2

    Topics: Acetates; Acetic Acid; Animals; Avoidance Learning; Behavior, Animal; Body Weight; Endorphins; Femal

1989
Fluorescent histochemical study on the localization of myofibroblasts in the healing of acetic acid-induced gastric ulcers in the rat.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: Acetates; Acetic Acid; Animals; Fibroblasts; Fluorescein-5-isothiocyanate; Fluoresceins; Histocytoch

1989
Prolylhydroxylase and collagenase activities in the healing of acetic acid-induced gastric ulcers in rats and the effects of cimetidine and elcatonin.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: Acetates; Acetic Acid; Animals; Calcitonin; Cimetidine; Hydrogen-Ion Concentration; Male; Microbial

1989
Roles of endogenous leukotrienes and prostaglandins in the healing of gastric ulcers induced by acetic acid in rats.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: Acetates; Acetic Acid; Animals; Benzoquinones; Gastric Mucosa; Leukotriene B4; Leukotrienes; Lipoxyg

1989
Characterization of metalloproteinases in rat gastric tissues with acetic acid-induced ulcers.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: Acetates; Acetic Acid; Animals; Enzyme Precursors; Famotidine; Gastric Mucosa; Gelatin; Male; Metall

1989
Influence of food-intake during a fixed period on hydrocortisone-induced relapse of acetic acid ulcers in rats.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: Acetates; Acetic Acid; Animals; Eating; Gastric Mucosa; Hydrocortisone; Male; Rats; Rats, Inbred Str

1989
Role of the mucus gel layer in the healing of acetic acid-induced gastric ulcers in rats.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: Acetates; Acetic Acid; Animals; Gels; Hydrogen-Ion Concentration; Male; Mucus; Rats; Rats, Inbred St

1989
Effects of human epidermal growth factor on natural and delayed healing of acetic acid-induced gastric ulcers in rats.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: Acetates; Acetic Acid; Animals; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gastric A

1989
[The role of polymorphonuclear leukocytes in the mechanisms of ulcerogenesis].
    Arkhiv patologii, 1989, Volume: 51, Issue:10

    Topics: Acetates; Acetic Acid; Animals; Gastric Mucosa; Histocytochemistry; Lysosomes; Male; Neutrophils; Ra

1989
[Experimental chronic stomach ulcer].
    Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR, 1989, Volume: 49, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Disease Models, Animal; Gastric Mucosa; Injections; Male; Rats; Rats

1989
Collagen and collagenase in ulcer tissue--1. The healing process of acetic acid ulcers in rats.
    The Tokai journal of experimental and clinical medicine, 1987, Volume: 12, Issue:3

    Topics: Acetates; Acetic Acid; Animals; Collagen; Gastric Mucosa; Hydroxyproline; Male; Microbial Collagenas

1987
Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin.
    Gastroenterology, 1989, Volume: 96, Issue:2 Pt 1

    Topics: Acetates; Acetic Acid; Animals; Dinoprostone; Gastric Acid; Gastric Mucosa; Indomethacin; Male; Rats

1989
[Effect of NaHCO3 infusion on the healing of acetic acid-induced gastric ulcer in rats].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1986, Volume: 83, Issue:2

    Topics: Acetates; Acetazolamide; Acetic Acid; Animals; Bicarbonates; Infusions, Parenteral; Male; Rats; Rats

1986
Production of metalloproteinase in gastric tissue with acetic acid-induced ulcer or taurocholic acid-induced gastritis.
    Journal of pharmacobio-dynamics, 1987, Volume: 10, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Collagen; Endopeptidases; Gastritis; Gelatin; Male; Metalloendopepti

1987
Suppression of gastric ulcer induced by stress and HCL-ethanol by intravenously administered metallothionein-II.
    Biochemical and biophysical research communications, 1988, Mar-15, Volume: 151, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Cimetidine; Ethanol; Hydrochloric Acid; Male; Metallothionein; Rats;

1988
Gastroprotective and ulcer healing effects of solon, a synthetic flavonoid derivative of sophoradin.
    Hepato-gastroenterology, 1987, Volume: 34, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Bicarbonates; Chalcone; Chalcones; Dinoprostone;

1987
[Lysosomal enzyme activity of the gastric mucosa in rats during experimental ulcer formation].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 104, Issue:10

    Topics: Acetates; Acetic Acid; Animals; Disease Models, Animal; Gastric Mucosa; Histamine; Lysosomes; Rats;

1987
Effects of 15(R)-15-methyl prostaglandin E2 (arbaprostil) on gastric secretion and various gastric lesions induced in rats.
    Japanese journal of pharmacology, 1986, Volume: 40, Issue:2

    Topics: Acetates; Acetic Acid; Administration, Oral; Animals; Arbaprostil; Aspirin; Dose-Response Relationsh

1986
Increasing action of teprenone, a new antiulcer agent, on high-molecular-weight glycoprotein in gastric mucus during the healing process of acetic acid-induced ulcer in rats.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Diterpenes; Gastric Mucosa; Glycoprot

1986
Effects of trimoprostil on healing and recurrence of acetic acid-induced gastric ulcer in rats.
    Japanese journal of pharmacology, 1986, Volume: 42, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Dinoprostone; Gastric Acid; Male; Pro

1986
[Synthesis of 3-aromatic ring substituted 2-(4-chlorobenzoylamino)propionic acid derivatives and their antiulcer activities].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1985, Volume: 105, Issue:11

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Chlorobenzoates; Propionates; Rats; Stomach Ulcer

1985
Healing-promoting action of teprenone, a new antiulcer agent on acetic acid ulcer in rats.
    Japanese journal of pharmacology, 1985, Volume: 38, Issue:3

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Diterpenes; Male; Polyenes; Proglumid

1985
Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103).
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:2

    Topics: Acetates; Acetic Acid; Aminopyrine; Animals; Anti-Ulcer Agents; Aspirin; Bethanechol Compounds; Cime

1985
Healing-promoting action of dried aluminium hydroxide gel evaluated by the method of histological measurements in acetic acid ulcer of rats.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:4

    Topics: Acetates; Acetic Acid; Aluminum Hydroxide; Animals; Male; Propantheline; Rats; Rats, Inbred Strains;

1985
[Changes in the biosynthetic activity of gastric glycoproteins during the healing process of acetic acid ulcer in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:5

    Topics: Acetates; Acetic Acid; Animals; Chromatography, Gel; Gastric Mucosa; Glucosamine; Glycoproteins; Mal

1985
Effect of elcatonin on experimental gastric and duodenal ulcers.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:1

    Topics: Acetates; Acetic Acid; Actihaemyl; Animals; Anti-Ulcer Agents; Aspirin; Calcitonin; Cimetidine; Cyst

1985
Effects of 5-acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one, a new anti-ulcer agent, on experimental acute and chronic ulcers.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:10

    Topics: Acetates; Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Aspirin; Benzofurans; Chronic Dise

1985