acetic acid has been researched along with Esophageal Neoplasms in 25 studies
Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.
Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Analysis of this large series showed that acetic acid-assisted evaluation of Barrett's esophagus detects neoplasia better than white light endoscopy, with sensitivity and specificity equal to that of histological analysis." | 3.76 | Acetic acid spray is an effective tool for the endoscopic detection of neoplasia in patients with Barrett's esophagus. ( Bhandari, P; Duku, M; Longcroft-Wheaton, G; Mead, R; Poller, D, 2010) |
| " The aim of this study was to investigate the effects of synbiotics in esophageal cancer patients receiving neoadjuvant chemotherapy on the intestinal microbiota and the adverse events of chemotherapy." | 2.84 | Randomized study of the effect of synbiotics during neoadjuvant chemotherapy on adverse events in esophageal cancer patients. ( Akita, H; Asahara, T; Fujiwara, Y; Gotoh, K; Ishikawa, O; Kobayashi, S; Miyata, H; Miyoshi, N; Motoori, M; Nomoto, K; Noura, S; Ohue, M; Omori, T; Saito, T; Sakon, M; Sugimura, K; Takahashi, H; Yano, M, 2017) |
| " The primary endpoint was the incidence of chemotherapy-related adverse events." | 2.84 | Randomized study of the effect of synbiotics during neoadjuvant chemotherapy on adverse events in esophageal cancer patients. ( Akita, H; Asahara, T; Fujiwara, Y; Gotoh, K; Ishikawa, O; Kobayashi, S; Miyata, H; Miyoshi, N; Motoori, M; Nomoto, K; Noura, S; Ohue, M; Omori, T; Saito, T; Sakon, M; Sugimura, K; Takahashi, H; Yano, M, 2017) |
| "Synbiotics during neoadjuvant chemotherapy in esophageal cancer patients reduced the occurrence of adverse events of chemotherapy through adjustments to the intestinal microbiota." | 2.84 | Randomized study of the effect of synbiotics during neoadjuvant chemotherapy on adverse events in esophageal cancer patients. ( Akita, H; Asahara, T; Fujiwara, Y; Gotoh, K; Ishikawa, O; Kobayashi, S; Miyata, H; Miyoshi, N; Motoori, M; Nomoto, K; Noura, S; Ohue, M; Omori, T; Saito, T; Sakon, M; Sugimura, K; Takahashi, H; Yano, M, 2017) |
| "Sixty-one patients with advanced esophageal cancer who were scheduled to receive neoadjuvant chemotherapy were randomly allocated to 2 groups." | 2.84 | Randomized study of the effect of synbiotics during neoadjuvant chemotherapy on adverse events in esophageal cancer patients. ( Akita, H; Asahara, T; Fujiwara, Y; Gotoh, K; Ishikawa, O; Kobayashi, S; Miyata, H; Miyoshi, N; Motoori, M; Nomoto, K; Noura, S; Ohue, M; Omori, T; Saito, T; Sakon, M; Sugimura, K; Takahashi, H; Yano, M, 2017) |
| "Acetic acid 2." | 2.78 | Duration of acetowhitening as a novel objective tool for diagnosing high risk neoplasia in Barrett's esophagus: a prospective cohort trial. ( Basford, P; Bhandari, P; Brown, J; Cowlishaw, D; Higgins, B; Longcroft-Wheaton, G, 2013) |
| "57 patients with Barrett's esophagus (mean length 3." | 2.73 | Comparison of computed virtual chromoendoscopy and conventional chromoendoscopy with acetic acid for detection of neoplasia in Barrett's esophagus. ( Ell, C; Fissler-Eckhoff, A; May, A; Nguyen-Tat, M; Pech, O; Pohl, J; Rabenstein, T, 2007) |
| "A squamous cell carcinoma was diagnosed and treated with chemotherapy, oesophagus-cardia resection and gastric tube reconstruction." | 2.41 | [Consequences of caustic damage of the esophagus]. ( Bartelsman, JF; Davids, PH; Tilanus, HW; van Lanschot, JJ, 2001) |
| "Acetic acid is a commonly available dye that has been used in the detection of neoplasia within Barrett's esophagus." | 1.40 | Acetic acid chromoendoscopy in Barrett's esophagus surveillance is superior to the standardized random biopsy protocol: results from a large cohort study (with video). ( Bhandari, P; Bhattacharyya, R; Longcroft-Wheaton, G; Tholoor, S; Tsagkournis, O, 2014) |
| "Data were collected from patients with Barrett's esophagus examined at a tertiary referral center, between July 2005 and November 2008 using Fujinon gastroscopes and EPX 4400 processor (n = 190)." | 1.36 | Acetic acid spray is an effective tool for the endoscopic detection of neoplasia in patients with Barrett's esophagus. ( Bhandari, P; Duku, M; Longcroft-Wheaton, G; Mead, R; Poller, D, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (20.00) | 29.6817 |
| 2010's | 17 (68.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Longcroft-Wheaton, G | 6 |
| Fogg, C | 1 |
| Chedgy, F | 1 |
| Kandiah, K | 3 |
| Murray, L | 1 |
| Dewey, A | 1 |
| Barr, H | 1 |
| Higgins, B | 2 |
| Poller, D | 2 |
| Jankowski, J | 1 |
| DeCaestecker, J | 1 |
| Bhandari, P | 7 |
| Kandel, P | 1 |
| Wallace, MB | 1 |
| Chedgy, FJQ | 1 |
| Subramaniam, S | 2 |
| Bassett, P | 1 |
| Repici, A | 1 |
| Sharma, P | 1 |
| Pech, O | 2 |
| Iwaya, Y | 1 |
| Rowsell, C | 1 |
| Gupta, V | 1 |
| Marcon, N | 1 |
| Brown, J | 1 |
| Basford, P | 1 |
| Cowlishaw, D | 2 |
| Saxena, P | 1 |
| Canto, MI | 1 |
| Verna, C | 1 |
| Feyles, E | 1 |
| Lorenzi, L | 1 |
| Rolle, E | 1 |
| Grassini, M | 1 |
| Giacobbe, U | 1 |
| Niola, P | 1 |
| Battaglia, E | 1 |
| Bassotti, G | 1 |
| Villanacci, V | 1 |
| Tholoor, S | 1 |
| Bhattacharyya, R | 1 |
| Tsagkournis, O | 1 |
| Coletta, M | 1 |
| Sami, SS | 1 |
| Nachiappan, A | 1 |
| Fraquelli, M | 1 |
| Casazza, G | 1 |
| Ragunath, K | 2 |
| Motoori, M | 1 |
| Yano, M | 1 |
| Miyata, H | 1 |
| Sugimura, K | 1 |
| Saito, T | 1 |
| Omori, T | 1 |
| Fujiwara, Y | 1 |
| Miyoshi, N | 1 |
| Akita, H | 1 |
| Gotoh, K | 1 |
| Takahashi, H | 1 |
| Kobayashi, S | 1 |
| Noura, S | 1 |
| Ohue, M | 1 |
| Asahara, T | 1 |
| Nomoto, K | 1 |
| Ishikawa, O | 1 |
| Sakon, M | 1 |
| Chedgy, FJ | 1 |
| Thayalasekaran, S | 1 |
| Duku, M | 1 |
| Mead, R | 1 |
| Kandaswamy, P | 1 |
| Camus, M | 1 |
| Coriat, R | 1 |
| Leblanc, S | 1 |
| Brezault, C | 1 |
| Terris, B | 1 |
| Pommaret, E | 1 |
| Gaudric, M | 1 |
| Chryssostalis, A | 1 |
| Prat, F | 1 |
| Chaussade, S | 1 |
| Yamagata, T | 1 |
| Hirasawa, D | 1 |
| Fujita, N | 1 |
| Obana, T | 1 |
| Sugawara, T | 1 |
| Ohira, T | 1 |
| Harada, Y | 1 |
| Maeda, Y | 1 |
| Koike, Y | 1 |
| Suzuki, K | 1 |
| Yamamoto, Y | 1 |
| Kusaka, J | 1 |
| Tanaka, M | 1 |
| Noda, Y | 1 |
| Lambert, R | 1 |
| Rey, JF | 2 |
| Sankaranarayanan, R | 1 |
| Vázquez-Iglesias, JL | 1 |
| Alonso-Aguirre, P | 1 |
| Diz-Lois, MT | 1 |
| Vázquez-Millán, MA | 1 |
| Alvarez, A | 1 |
| Lorenzo, MJ | 1 |
| Pohl, J | 1 |
| May, A | 1 |
| Rabenstein, T | 2 |
| Nguyen-Tat, M | 1 |
| Fissler-Eckhoff, A | 1 |
| Ell, C | 1 |
| Curvers, W | 1 |
| Baak, L | 1 |
| Kiesslich, R | 1 |
| Van Oijen, A | 1 |
| Scholten, P | 1 |
| Seitz, U | 1 |
| Ten Kate, F | 1 |
| Fockens, P | 1 |
| Bergman, J | 1 |
| Davids, PH | 1 |
| Bartelsman, JF | 1 |
| Tilanus, HW | 1 |
| van Lanschot, JJ | 1 |
| Alexandrov, VA | 1 |
| Novikov, AI | 2 |
| Zabezhinsky, MA | 1 |
| Stolyarov, VI | 1 |
| Petrov, AS | 1 |
| Aleksandrov, VA | 1 |
| Zabezhinskiĭ, MA | 1 |
| Stoliarov, VI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acetic Acid vs Seattle Protocol for Neoplastic Lesions in Barrett Esophagus[NCT04054713] | 76 participants (Anticipated) | Interventional | 2019-07-03 | Recruiting | |||
| "Acetic Acid Chromoendoscopy in Barrett's Esophagus Surveillance is Superior to the Standardized Random Biopsy Protocol in Detecting Neoplasia: A Prospective Randomized Study"[NCT02614703] | Phase 2/Phase 3 | 60 participants (Actual) | Interventional | 2017-03-10 | Terminated (stopped due to Sample was under-powered) | ||
| Acetic Acid Chromoendoscopy for Judging Extent of Gastric Intestinal Metaplasia[NCT01499576] | 126 participants (Actual) | Interventional | 2011-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Spray of Acetic Acid into the esophageal mucosa during routine esophageal biopsies for Barrett's esophagus surveillance increases the yield of neoplasia. (NCT02614703)
Timeframe: 142 seconds
| Intervention | participants (Number) |
|---|---|
| Chromoendoscopy Using Acetic Acid 2.5% | 1 |
| Standard Random Esophageal Biopsies | 0 |
"The findings of chromoendoscopy will be interpretated by two endoscoipists (read as positive or negative finding) independently.~We calculate the Kappa index of agreement for the acetic acid chromoendoscopy." (NCT01499576)
Timeframe: One month after the completion of the study
| Intervention | Kappa index of agreement (Number) |
|---|---|
| Acetic Acid Spraying | 0.808 |
Number of Participants with Adverse Events. Assess kind of side effect and severity. Measured by interview with a physician, just after the procedure and 1weak later. (NCT01499576)
Timeframe: up to 1week after the acetic acid chromoendoscopy
| Intervention | participants (Number) | |
|---|---|---|
| Epigastric discomfort | Neck discomfort | |
| Acetic Acid Spraying | 9 | 2 |
Endoscopist judges the presence and the extent of gastric intestinal metaplasia during acetic acid chromoendoscopy. Endoscopist perform five endoscopic biopsies according to the protocol. The degree of agreement between the chromoendoscopy and the endoscopic biopsy is assessed as %. (NCT01499576)
Timeframe: 3 months after the completion of the study (a pathologist reviewed all the biopsy slide)
| Intervention | percentage of lesions (Number) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Overall Sensitivity | Overall Specificity | Overall Accuracy | Body Sensitivity | Body Specificity | Body Accuracy | Antrum Sensitivity | Antrum Specificity | Antrum Accuracy | |
| Acetic Acid Spraying | 78.5 | 94.4 | 89.2 | 67.1 | 94.7 | 89.4 | 80.9 | 93.6 | 88.4 |
6 reviews available for acetic acid and Esophageal Neoplasms
| Article | Year |
|---|---|
The Role of Adjunct Imaging in Endoscopic Detection of Dysplasia in Barrett's Esophagus.
Topics: Acetic Acid; Barrett Esophagus; Esophageal Neoplasms; Esophagoscopy; Esophagus; Humans; Indicators a | 2017 |
Red flag imaging techniques in Barrett's esophagus.
Topics: Acetic Acid; Adenocarcinoma; Barrett Esophagus; Early Detection of Cancer; Esophageal Neoplasms; Eso | 2013 |
Acetic acid chromoendoscopy for the diagnosis of early neoplasia and specialized intestinal metaplasia in Barrett's esophagus: a meta-analysis.
Topics: Acetic Acid; Adenocarcinoma; Barrett Esophagus; Early Detection of Cancer; Esophageal Neoplasms; Eso | 2016 |
Acetic acid chromoendoscopy: Improving neoplasia detection in Barrett's esophagus.
Topics: Acetic Acid; Adenocarcinoma; Barrett Esophagus; Esophageal Neoplasms; Esophagoscopy; Humans; Indicat | 2016 |
Magnification and chromoscopy with the acetic acid test.
Topics: Acetic Acid; Adenocarcinoma; Barrett Esophagus; Carcinoma, Squamous Cell; Colposcopy; Esophageal Neo | 2003 |
[Consequences of caustic damage of the esophagus].
Topics: Acetic Acid; Adult; Burns, Chemical; Carcinoma, Squamous Cell; Deglutition Disorders; Dilatation; Es | 2001 |
3 trials available for acetic acid and Esophageal Neoplasms
| Article | Year |
|---|---|
Duration of acetowhitening as a novel objective tool for diagnosing high risk neoplasia in Barrett's esophagus: a prospective cohort trial.
Topics: Acetic Acid; Adult; Aged; Aged, 80 and over; Area Under Curve; Barrett Esophagus; Carcinoma; Esophag | 2013 |
Randomized study of the effect of synbiotics during neoadjuvant chemotherapy on adverse events in esophageal cancer patients.
Topics: Acetic Acid; Adult; Aged; Aged, 80 and over; Cisplatin; Docetaxel; Endpoint Determination; Esophagea | 2017 |
Comparison of computed virtual chromoendoscopy and conventional chromoendoscopy with acetic acid for detection of neoplasia in Barrett's esophagus.
Topics: Acetic Acid; Administration, Topical; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Biopsy; Dis | 2007 |
16 other studies available for acetic acid and Esophageal Neoplasms
| Article | Year |
|---|---|
A feasibility trial of Acetic acid-targeted Biopsies versus nontargeted quadrantic biopsies during BArrett's surveillance: the ABBA trial.
Topics: Acetic Acid; Barrett Esophagus; Biopsy; Esophageal Neoplasms; Esophagoscopy; Feasibility Studies; Hu | 2020 |
[French comment on article Development and validation of a training module on the use of acetic acid for the detection of Barrett's neoplasia1].
Topics: Acetic Acid; Barrett Esophagus; Esophageal Neoplasms; Humans | 2017 |
International development and validation of a classification system for the identification of Barrett's neoplasia using acetic acid chromoendoscopy: the Portsmouth acetic acid classification (PREDICT).
Topics: Acetic Acid; Barrett Esophagus; Biopsy; Clinical Competence; Esophageal Neoplasms; Esophagoscopy; Es | 2018 |
[French comment on article Systematic assessment with I-SCAN magnification endoscopy and acetic acid improves dysplasia detection in patients with Barrett's esophagus].
Topics: Acetic Acid; Barrett Esophagus; Endoscopy; Esophageal Neoplasms; Esophagoscopy; Humans; Precancerous | 2017 |
Buried Barrett's Adenocarcinoma Clearly Demonstrated with Acetic Acid Chromoendoscopy.
Topics: Acetic Acid; Adenocarcinoma; Aged; Barrett Esophagus; Biopsy; Esophageal Neoplasms; Esophagoscopy; E | 2018 |
Commentaire de travail de G. Longcroft-Wheaton et al., pp. 426.
Topics: Acetic Acid; Barrett Esophagus; Carcinoma; Esophageal Neoplasms; Female; Humans; Male; Precancerous | 2013 |
I-SCAN targeted versus random biopsies in Barrett's oesophagus.
Topics: Acetic Acid; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Biopsy; Cohort Studies; Esophageal N | 2014 |
Acetic acid chromoendoscopy in Barrett's esophagus surveillance is superior to the standardized random biopsy protocol: results from a large cohort study (with video).
Topics: Acetic Acid; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Biopsy; Cohort Studi | 2014 |
Acetic acid chromoendoscopy in Barrett's esophagus surveillance is superior to the standardized random biopsy protocol: results from a large cohort study (with video).
Topics: Acetic Acid; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Biopsy; Cohort Studi | 2014 |
Acetic acid chromoendoscopy in Barrett's esophagus surveillance is superior to the standardized random biopsy protocol: results from a large cohort study (with video).
Topics: Acetic Acid; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Biopsy; Cohort Studi | 2014 |
Acetic acid chromoendoscopy in Barrett's esophagus surveillance is superior to the standardized random biopsy protocol: results from a large cohort study (with video).
Topics: Acetic Acid; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Biopsy; Cohort Studi | 2014 |
Acetic acid spray is an effective tool for the endoscopic detection of neoplasia in patients with Barrett's esophagus.
Topics: Acetic Acid; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Biopsy; Esophageal Neoplasms; Female | 2010 |
Acetic acid-enhanced chromoendoscopy is more cost-effective than protocol-guided biopsies in a high-risk Barrett's population.
Topics: Acetic Acid; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Biopsy; Cost-Benefit | 2012 |
Helpfulness of the combination of acetic acid and FICE in the detection of Barrett's epithelium and Barrett's associated neoplasias.
Topics: Acetic Acid; Adult; Aged; Barrett Esophagus; Endoscopy, Gastrointestinal; Esophageal Neoplasms; Esop | 2012 |
Efficacy of acetic acid-spraying method in diagnosing extension of Barrett's cancer under the squamous epithelium.
Topics: Acetic Acid; Aged; Barrett Esophagus; Diagnosis, Differential; Epithelium; Esophageal Neoplasms; Eso | 2012 |
Acetic acid allows effective selection of areas for obtaining biopsy samples in Barrett's esophagus.
Topics: Acetic Acid; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Biopsy; Esophageal N | 2007 |
Chromoendoscopy and narrow-band imaging compared with high-resolution magnification endoscopy in Barrett's esophagus.
Topics: Acetic Acid; Aged; Aged, 80 and over; Barrett Esophagus; Coloring Agents; Esophageal Neoplasms; Esop | 2008 |
The stimulating effect of acetic acid, alcohol and thermal burn injury on esophagus and forestomach carcinogenesis induced by N-nitrososarcosin ethyl ester in rats.
Topics: Acetates; Acetic Acid; Animals; Carcinoma in Situ; Carcinoma, Squamous Cell; Cocarcinogenesis; Esoph | 1989 |
[Stimulating effects of 3% acetic acid on the induction of esophageal tumors in rats].
Topics: Acetates; Acetic Acid; Animals; Carcinogens; Carcinoma, Squamous Cell; Drug Synergism; Esophageal Ne | 1988 |