acetic acid has been researched along with Disease Models, Animal in 538 studies
Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty rats were randomly separated into five groups (n = 10) with different durations (30 s, 5, 10, and 20 min) of exposure of the colon to 4% acetic acid and colitis was investigated for 0-9 days." | 8.12 | Improving Animal Model of Induced Colitis by Acetic Acid in Terms of Fibrosis and Inflammation Incidence in the Colon. ( Babaei, A; Bahrami, G; Madani, H; Malekshahi, H; Miraghaee, S, 2022) |
| " The anthocyanidin effects were examined in gastric ulcer mouse models induced by ethanol, non-steroidal anti-inflammatory drugs (NSAIDs), ischemia-reperfusion (IR), acetic acid and duodenal ulcer induced by polypharmacy." | 8.02 | Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation. ( Dos Santos, RC; Fagundes, FL; Pereira, QC; Zarricueta, ML, 2021) |
| " The effect of the extract on acute inflammation was analyzed by increasing vascular permeability via acetic acid and xylene induced ear edema among mice." | 8.02 | Effect of Nectaroscordum koelzi Methanolic Extract on Acute and Chronic Inflammation in Male Mice. ( Alipour, M; Hasanvand, KH; Khaksarian, M; Mahmoudvand, H; Nadri, S; Naizi, M, 2021) |
| "The findings showed that the extract was effective on acute inflammation induced by acetic acid in mice." | 8.02 | Effect of Nectaroscordum koelzi Methanolic Extract on Acute and Chronic Inflammation in Male Mice. ( Alipour, M; Hasanvand, KH; Khaksarian, M; Mahmoudvand, H; Nadri, S; Naizi, M, 2021) |
| " To evaluate the analgesic effects of AC, 4 different pain models including hot plate assay, acetic acid writhing assay, formalin and CFA induced pain models were adopted in this study." | 8.02 | Comparison of analgesic activities of aconitine in different mice pain models. ( Chen, J; Deng, J; Feng, Q; Han, J; Huang, Q; Leung, EL; Liu, Z; Lu, L; Qi, X; Wang, D; Wang, Y; Zhang, Y, 2021) |
| " speciosa accelerated healing of gastric ulcers even in presence of indomethacin, while decreasing bacterial loads in rats' stomachs." | 8.02 | Eremomastax speciosa (Hochst.) Cufod. counteracts the delaying effect of indomethacin on Helicobacter pylori-associated chronic gastric ulcers healing. ( Amang, AP; Choudhary, MI; Enow-Orock, GE; Maharjan, R; Mezui, C; Siwe, GT; Tan, PV; Zondegoumba, NE, 2021) |
| "It was shown that finasteride, a 5α-reductase inhibitor (50 mg/kg, intraperitoneally) produced analgesic and antiexudative effects in experimental peritonitis induced by intraperitoneal injection of 1% acetic acid." | 7.96 | Antiexudative Effects of Finasteride and a New Pyrazolo[C]Pyridine Derivative GIZh-72 in Acetic Acid-Induced Experimental Peritonitis. ( Ivanova, EA; Kalinina, TS; Kudryashov, NV; Kurshin, AA; Shimshirt, AA; Voronina, TA; Zhmurenko, LA, 2020) |
| "The phosphodiesterase-3 inhibitor, cilostazol has been recently shown to protect against chemically induced colitis in animal models." | 7.96 | Cilostazol protects against acetic acid-induced colitis in rats: Possible role for cAMP/SIRT1 pathway. ( Elhassanny, AEM; Elshazly, SM; Mahmoud, NM, 2020) |
| " An acetic acid-induced colitis model was produced in groups 2, 3 and 4 and was administered normal saline, topical GO and topical and systemic GO, respectively." | 7.96 | Effects of garlic oil (allium sativum) on acetic acid-induced colitis in rats: Garlic oil and experimental colitis. ( Can, M; Kılınç, F; Köktürk, F; Şen Tanrıkulu, C; Tanrıkulu, Y, 2020) |
| "GO can reduce colonic damage and inflammation in the acetic acid-induced colitis model, with effects on both local and systemic treatments, but with a more pronounced effect in local treatment." | 7.96 | Effects of garlic oil (allium sativum) on acetic acid-induced colitis in rats: Garlic oil and experimental colitis. ( Can, M; Kılınç, F; Köktürk, F; Şen Tanrıkulu, C; Tanrıkulu, Y, 2020) |
| "Here, we found that intratesticular bradykinin evokes pain behavior via stimulation of bradykinin B2 receptors and that intratesticular acetic acid injection induces intratesticular bradykinin synthesis, consequently leading to pain behavior." | 7.88 | Intratesticular Bradykinin Involvement in Rat Testicular Pain Models. ( Fujimoto, K; Masuda, N; Takeda, M; Yoshino, T; Yoshioka, K; Yuyama, H, 2018) |
| "To clarify the role of bradykinin in urogenital pain, we investigated bradykinin involvement in rat models of testicular pain." | 7.88 | Intratesticular Bradykinin Involvement in Rat Testicular Pain Models. ( Fujimoto, K; Masuda, N; Takeda, M; Yoshino, T; Yoshioka, K; Yuyama, H, 2018) |
| "An injection of bradykinin into the testes of conscious rats induced pain behaviors that were dose-proportionally reduced by prior administration of FK3657." | 7.88 | Intratesticular Bradykinin Involvement in Rat Testicular Pain Models. ( Fujimoto, K; Masuda, N; Takeda, M; Yoshino, T; Yoshioka, K; Yuyama, H, 2018) |
| "The purpose of our investigative work has been to determine whether there can be therapeutic roles in the administration of sildenafil citrate, heparin and several neuropeptides on an animal model where gastric ulcers were induced with acetic acid, and to compare their efficacy." | 7.85 | Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017) |
| "Overall the data indicate that low dose heparin, and especially sildenafil citrate and neuropeptides, can be used clinically as an alternative approach in the treatment of the gastric ulcer." | 7.85 | Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017) |
| " This study investigates the ameliorative effect of Ocimum basilicum essential oil on an acetic acid-induced colitis model in rats." | 7.83 | Protective Effect of Ocimum basilicum Essential Oil Against Acetic Acid-Induced Colitis in Rats. ( Ghannadi, AR; Mehrzadi, S; Minaiyan, M; Rashidian, A; Roohi, P, 2016) |
| "This study aimed to investigate the involvement of opioid receptors in the systemic and peripheral antinociceptive activities of montelukast in different animal models of pain." | 7.83 | Involvement of opioid receptors in the systemic and peripheral antinociceptive actions of montelukast in the animal models of pain. ( Alboghobeish, S; Ghorbanzadeh, B; Mansouri, MT; Sahraei, H, 2016) |
| "The model of gastric ulcer was imitated by acetic acid in rats, and AL was gavaged." | 7.81 | Comparison of the anti-ulcer activity between the crude and bran-processed Atractylodes lancea in the rat model of gastric ulcer induced by acetic acid. ( Cai, Q; Jia, TZ; Jiang, N; Ma, MY; Min, DY; Yu, Y; Yuan, Y, 2015) |
| " There is no study showing the efficacy of fostamatinib, with proven effects on some inflammatory diseases, on ulcerative colitis." | 7.81 | The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis. ( Aksit, H; Ayvaz, S; Can, G; Can, H; Demirtas, S; Karaca, T; Korkmaz, U; Kurt, M; Yilmaz, B, 2015) |
| "The study included 28 male Sprague-Dawley rats, randomly divided into control group, fostamatinib group, colitis group and fostamatinib + colitis group, each containing seven rats." | 7.81 | The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis. ( Aksit, H; Ayvaz, S; Can, G; Can, H; Demirtas, S; Karaca, T; Korkmaz, U; Kurt, M; Yilmaz, B, 2015) |
| "Fostamatinib reduced the inflammatory damage in the experimental colitis." | 7.81 | The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis. ( Aksit, H; Ayvaz, S; Can, G; Can, H; Demirtas, S; Karaca, T; Korkmaz, U; Kurt, M; Yilmaz, B, 2015) |
| " Additionally, anti-inflammatory function of gelsolin (8 mg/mouse) compared with anti-inflammatory drug diclofenac sodium (10 mg/kg)] was confirmed in the carrageenan injection induced paw edema where latter was measured by vernier caliper and fluorescent tomography imaging." | 7.81 | Analgesic and Anti-Inflammatory Properties of Gelsolin in Acetic Acid Induced Writhing, Tail Immersion and Carrageenan Induced Paw Edema in Mice. ( Chopra, BS; Choudhary, V; Garg, R; Gupta, AK; Khatri, N; Parasar, D; Sagar, A, 2015) |
| " Opioid coadministration had a synergistic effect in the acute tonic pain (acetic acid writhing test), acute phasic pain (tail flick test) and inflammatory pain (orofacial formalin test)." | 7.79 | Systemic synergism between codeine and morphine in three pain models in mice. ( Miranda, HF; Noriega, V; Prieto, JC; Sierralta, F; Zepeda, RJ, 2013) |
| "The effect of fumonisin B1, an inhibitor of ceramide synthase, and of d,l,-threo-1-phenyl-2-hexadecanoylamino-3-morpholino-1-propanol (PPMP) and N-butyldeoxynojirimycin (NB-DNJ), both inhibitors of glucosylceramide synthase, on the accumulation of ceramide and formation of gastric ulcer were examined in the rat model of acetic acid-induced gastric ulcer." | 7.79 | Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. ( Hibi, T; Miura, S; Mizushima, T; Nagata, H; Nakashita, M; Suzuki, H; Taki, T; Uehara, K, 2013) |
| "Fumonisin B1 attenuated acetic acid-induced gastric ulcer formation, associated with a decrease in the number of apoptotic cells." | 7.79 | Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. ( Hibi, T; Miura, S; Mizushima, T; Nagata, H; Nakashita, M; Suzuki, H; Taki, T; Uehara, K, 2013) |
| "To evaluate the antioxidant effect of an extract of the plant Boswellia serrata in an experimental model of acute ulcerative colitis induced by administration of acetic acid (AA) in rats." | 7.78 | Effect of Boswellia serrata on antioxidant status in an experimental model of colitis rats induced by acetic acid. ( Fillmann, HS; Hartmann, RM; Marroni, NP; Morgan Martins, MI; Tieppo, J, 2012) |
| " The pharmacological activity of AFE and pure scopoletin at the same equivalent dose present in AFE was investigated in rat on gastro-esophageal inflammatory models (acid reflux esophagitis, acute gastritis induced by ethanol and serotonin, and chronic gastric ulcer induced by acetic acid); gastric biochemical parameters and gastrointestinal motility." | 7.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
| "50 g/kg) significantly prevented the formation of acid reflux esophagitis, reduced the formation of ethanol-induced acute gastric lesions, suppressed the development of gastric lesions in response to serotonin, and accelerated the healing of acetic acid-induced chronic gastric ulcer in rats with equal potency to those obtained by standard antisecretory agents (ranitidine and lansoprazole)." | 7.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
| " (Rubiaceae) fruit, commonly known as "Noni", in an aqueous extract preparation (AFE) as used in Thai traditional medicine and its biomarker scopoletin on gastro-esophageal inflammatory models that are related to the claimed pharmacological properties of AFE and/or resembled the human esophagitis or gastric ulcer." | 7.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
| " Milnacipran, a serotonin/noradrenalin reuptake inhibitor, has recently been approved in the USA for fibromyalgia, a chronic pathology characterized by diffused/chronic musculoskeletal pain, and a high prevalence of irritable bowel syndrome." | 7.77 | Milnacipran is active in models of irritable bowel syndrome and abdominal visceral pain in rodents. ( Aliaga, M; Ardid, D; Bardin, L; Depoortère, R; Meleine, M; Muller, E; Newman-Tancredi, A, 2011) |
| " This study aims to investigate granisetron, a 5-HT( 3) receptor antagonist, in acetic acid-induced rat colitis and probable involvement of 5-HT(3) receptors." | 7.76 | Granisetron ameliorates acetic acid-induced colitis in rats. ( Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mousavizadeh, K; Rahimian, R; Rasouli, MR, 2010) |
| "This study compared effects of the mu opioid receptor agonist morphine (an acknowledged analgesic), the dopamine receptor antagonist haloperidol (a non-analgesic sedative), the adenosine receptor antagonist caffeine (a non-analgesic stimulant) and the neurokinin-1 receptor antagonist CJ 11,974-01 (a candidate analgesic) on acetic acid-induced writhing (a traditional pain-stimulated behavior) and acetic acid-induced suppression of locomotor activity (a pain-depressed behavior) in male ICR mice." | 7.75 | Targeting pain-depressed behaviors in preclinical assays of pain and analgesia: drug effects on acetic acid-depressed locomotor activity in ICR mice. ( Adams, C; Bilsky, EJ; Cormier, J; Dunbar, C; Mercer, H; Negus, SS; Stevenson, GW, 2009) |
| "In the present study, we compared the effects of alpha-tocopherol and probucol, antioxidants, on the healing of acetic acid-induced gastric ulcers in 8-, 48- and 96-week-old rats." | 7.74 | Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol. ( Ishihara, M; Ito, M; Kojima, R, 2008) |
| "We investigated the effects of glutamine on markers of oxidative stress, nuclear factor kappaB (NF-kappaB) activation, and pro-inflammatory mediators in a rat model of experimental colitis induced by intracolonic administration of 7% acetic acid." | 7.74 | Glutamine inhibits over-expression of pro-inflammatory genes and down-regulates the nuclear factor kappaB pathway in an experimental model of colitis in the rat. ( Fillmann, H; González-Gallego, J; Kretzmann, NA; Llesuy, S; Marroni, N; San-Miguel, B; Tuñón, MJ, 2007) |
| "These data demonstrated the comparable efficacy of gabapentin with morphine in visceral pain." | 7.74 | Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice. ( Meymandi, MS; Sepehri, G, 2008) |
| " Here, the antinociceptive effects of MOR agonists, the 6beta-glycine derivative of 14-O-methyloxymorphone (HS-731), DAMGO and morphine were evaluated in a mouse model of visceral pain." | 7.74 | DAMGO and 6beta-glycine substituted 14-O-methyloxymorphone but not morphine show peripheral, preemptive antinociception after systemic administration in a mouse visceral pain model and high intrinsic efficacy in the isolated rat vas deferens. ( Al-Khrasani, M; Friedmann, T; Furst, S; Király, K; Riba, P; Schmidhammer, H; Spetea, M, 2007) |
| "Experimental colitis induced by acetic acid has been used extensively as a model for intestinal inflammatory disease." | 7.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| "To assess the cytokine expression pattern identified through immunohistochemistry in colonic mucosa after experimental colitis induced by acetic acid and establish the relationship between this pattern and the presence of macroscopic lesions." | 7.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| "Adult male Wistar rats (n = 39) were divided at random into 4 groups: NC45 and NC24 (control without colitis; sacrificed at 45 minutes and 24 hours, respectively); and WC45 and WC24 (with experimental colitis induced by acetic acid; sacrificed at 45 minutes and 24 hours, respectively)." | 7.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| " Experimental colitis induced by acetic acid is a useful model for the development of studies assessing the role of cytokines in the inflammation of mucosa as well as anti-cytokine therapies." | 7.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| ", was investigated using a model of acetic acid-induced colitis in mice." | 7.73 | Protective effect of comaruman, a pectin of cinquefoil Comarum palustre L., on acetic acid-induced colitis in mice. ( Markov, PA; Nikitina, IR; Ovodov, YS; Ovodova, RG; Popov, SV, 2006) |
| " We aimed to investigate the antioxidant effect and the histopathologic changes caused by Gingko biloba on acetic acid-induced colitis." | 7.73 | The effects of Gingko biloba extract on acetic acid-induced colitis in rats. ( Aladağ, M; Ara, C; Demirel, U; Firat, S; Harputluoglu, MM; Hilmioğlu, F; Karadağ, N; Karincaoğlu, M; Temel, I; Yücel, N, 2006) |
| "Thus, a preventive effect of pectin from the common cranberry, namely oxycoccusan OP, on acetic acid-induced colitis in mice was detected." | 7.73 | Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice. ( Markov, PA; Nikitina, IR; Ovodov, YS; Petrishev, S; Popov, SV; Smirnov, V, 2006) |
| " Therefore, we assessed whether a series of desferrithiocin analogs, both carboxylic acids and hydroxamates, could (1) either promote or diminish the iron-mediated oxidation of ascorbate, (2) quench a model radical species, 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+), and (3) when applied topically, prevent acetic acid-induced colitis in rats." | 7.72 | Prevention of acetic acid-induced colitis by desferrithiocin analogs in a rat model. ( Bergeron, RJ; Nguyen, JN; Sninsky, CA; Weimar, WR; Wiegand, J, 2003) |
| " Indomethacin abolished the gross mucosal protective effect by 1% AA pretreatment in 8% AA-derived colitis in normal rats while the NS398 had no effect." | 7.72 | Acetic acid-derived prostaglandin-dependent colonic adaptive cytoprotection is preserved in chronic colitis: role of cyclo-oxygenase. ( Asama, T; Chisato, N; Kasai, S; Kono, T; Ohara, K; Yoneda, M, 2003) |
| "The present work was done to investigate the possible effects of thymoquinone on acetic acid-induced colitis in rats." | 7.72 | Thymoquinone protects against experimental colitis in rats. ( Mahgoub, AA, 2003) |
| "We previously discovered that a 4-wk course of indomethacin delivered to rats with acetic acid ulcers resulted in production of "unhealed gastric ulcers" that persisted for up to 12 wks after treatment cessation." | 7.72 | Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats. ( Amagase, K; Okabe, S; Tsukimi, Y; Yokota, M, 2003) |
| "Colitis reduces the blood and tissue levels of adenosine deaminase and adenylate deaminase." | 7.71 | Blood purine and energy status in rats with colitis. ( Al-Awadi, FM; Khan, I, 2001) |
| "To investigate the possible role of cyclooxygenase-2 (COX-2) inhibitor NS-398 in formation and healing of acetic acid-induced gastric ulcer in rats." | 7.71 | [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001) |
| "Fourty eight male Sprague-Dawley rats weighed 160-180 g were perfused with acetic acid into the stomach to induce gastric ulcer and then divided into two groups." | 7.71 | [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001) |
| "NS-398 inhibits COX-2 activity, thus alleviating inflammatory reaction in acetic acid induced gastric ulcer and averting further damage of tissues." | 7.71 | [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001) |
| "The healing of experimental gastric ulcers induced in rats is consistently delayed upon chronic treatment with indomethacin." | 7.70 | A new ulcer model, "unhealed gastric ulcers", induced by chronic treatment with indomethacin in rats with acetic acid ulcers. ( Amagase, K; Okabe, S, 1999) |
| " Peptides were active against acetic acid-induced peritonitis in the rats." | 7.70 | Antiinflammatory activity of adrenomedullin in the acetic acid peritonitis in rats. ( Amico-Roxas, M; Caruso, A; Clementi, G; Cutuli, VM; Mangano, NG; Prato, A, 1999) |
| "The effects of cimetidine, omeprazole and atropine sulfate on the healing of acetic acid-induced gastric ulcers in rats with limited food intake time (9:00-10:00 a." | 7.69 | Effect of cimetidine and omeprazole on gastric ulcer healing of rats with limited food intake time. ( Ito, M; Kojima, R; Segami, T; Suzuki, Y; Tsukahara, T, 1994) |
| "In our study we have tried to compare the prophylactic effects of superoxide dismutase (SOD), SOD+catalase (CAT), desferrioxamine, verapamil and disulfiram, which are all free oxygen radical (FOR) scavengers, in an animal model of experimental acetic acid colitis." | 7.69 | The prophylactic effects of superoxide dismutase, catalase, desferrioxamine, verapamil and disulfiram in experimental colitis. ( Cokneşelí, B; Köksoy, FN; Köse, H; Soybír, GR; Yalçin, O, 1997) |
| "We found indomethacin aggravates healed gastric ulcers (ulcer relapse) in rats." | 7.69 | Prevention of gastric ulcer relapse induced by indomethacin in rats by a mutein of basic fibroblast growth factor. ( Asano, S; Inada, I; Maeda, R; Murakami, I; Sato, F; Satoh, H; Shino, A, 1997) |
| " Therefore, the aim of this study was to examine the role of collagenase and gelatinases A and B in the development and healing of acetic acid-induced gastric ulcer in rats." | 7.69 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
| "Gastric ulcer was induced by injecting 20 microliters glacial acetic acid into gastric wall of rat stomachs." | 7.69 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
| "The therapeutic efficacy of the leukocyte recruitment inhibitor, NPC 15669 (N-[9H-(2,7-dimethylfluoren-9-yl-methoxy)carbonyl]-L-leucine), was evaluated through the time course of acetic acid colitis in rats." | 7.68 | The leukocyte recruitment inhibitor, NPC 15669 accelerates healing in acetic acid-induced colitis. ( Lowe, VC; Noronha-Blob, L, 1993) |
| "The extent of the small intestinal injury following experimental acetic acid induction of colitis in rats was examined." | 7.68 | Acetic acid-induced colitis results in bystander ileal injury. ( Cui, N; Empey, LR; Fedorak, RN, 1993) |
| "The effects of ketotifen, a 'mast cell stabiliser,' on two models of experimental colitis were examined." | 7.68 | Ketotifen effectively prevents mucosal damage in experimental colitis. ( Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D, 1992) |
| "To clarify the mechanism of gastric ulcer recurrence, we studied acetic acid-induced gastric ulcers." | 7.68 | Evaluation of acetic acid-induced gastric ulcers in rats by scanning acoustic microscopy. ( Goto, H; Hase, S; Mizutani, K; Niwa, Y; Ohashi, S; Tsukamoto, Y, 1991) |
| " To more fully evaluate the role of arachidonic acid metabolites in the mediation of intestinal inflammation, we studied arachidonate metabolism in an animal model: acetic acid colitis in the rat." | 7.67 | Metabolism of arachidonic acid in acetic acid colitis in rats. Similarity to human inflammatory bowel disease. ( Sharon, P; Stenson, WF, 1985) |
| "Ulcerative colitis is a chronic inflammatory disease, profoundly affecting the patient's quality of life and is associated with various complications." | 5.72 | Linagliptin ameliorates acetic acid-induced colitis via modulating AMPK/SIRT1/PGC-1α and JAK2/STAT3 signaling pathway in rats. ( El-Bahy, AAZ; El-Ghannam, MS; El-Yamany, MF; Nassar, NN; Saad, MA, 2022) |
| "Colitis was induced in rats by acetic acid and the rats were divided into four groups where one group served as experimental control and the other groups were treated with two doses of methanol extract of dried latex of C." | 5.51 | Protection afforded by methanol extract of Calotropis procera latex in experimental model of colitis is mediated through inhibition of oxidative stress and pro-inflammatory signaling. ( Das, P; Kumar, VL; Pandey, A; Verma, S, 2019) |
| "treatment with oxyntomodulin during the second, but not the first phase." | 5.48 | Antinociceptive profiles and mechanisms of centrally administered oxyntomodulin in various mouse pain models. ( Hong, JW; Jang, SP; Lee, HJ; Lee, JR; Park, SH; Suh, HW, 2018) |
| "Gastric ulcers was induced in the animals of 12 groups with one untreated group being left as the control (Group I - control; given normal saline (NS))." | 5.46 | Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017) |
| "Kaempferol was shown to attenuate the expansion of inflammatory lesions seen in ethanol (EtOH)/HCl- and aspirin-induced gastritis, LPS/caerulein (CA) triggered pancreatitis, and acetic acid-induced writhing." | 5.42 | Kaempferol, a dietary flavonoid, ameliorates acute inflammatory and nociceptive symptoms in gastritis, pancreatitis, and abdominal pain. ( Baek, KS; Cho, JY; Ha, VT; Kim, E; Kim, HG; Kim, JH; Kim, SH; Lee, MN; Park, JG; Sung, GH; Sung, NY; Yang, S; Yang, WS; Yi, YS, 2015) |
| "Ulcerative colitis is a chronic inflammatory disease and involves multiple etiological factors." | 5.39 | Protective effects of N-acetylcysteine on acetic acid-induced colitis in a porcine model. ( Chen, X; Ding, B; Hou, Y; Liu, Y; Long, M; Wang, L; Wang, Q; Wu, G; Yi, D, 2013) |
| "Quercetin (1) is an anti-inflammatory and antioxidant flavonoid." | 5.39 | Quercetin-loaded microcapsules ameliorate experimental colitis in mice by anti-inflammatory and antioxidant mechanisms. ( Baracat, MM; Casagrande, R; Colombo, BB; Fattori, V; Georgetti, SR; Guazelli, CF; Verri, WA; Vicentini, FT, 2013) |
| "The role of antidepressants in the treatment of visceral pain has not been extensively examined." | 5.37 | Milnacipran is active in models of irritable bowel syndrome and abdominal visceral pain in rodents. ( Aliaga, M; Ardid, D; Bardin, L; Depoortère, R; Meleine, M; Muller, E; Newman-Tancredi, A, 2011) |
| "Colitis was rendered by instillation of 1 mL of 4% acetic acid (vol/vol) and after 1 hour, granisetron (2 mg/kg), dexamethasone (1 mg/kg), meta-chlorophenylbiguanide (mCPBG, 5 mg/kg), a 5-HT( 3) receptor agonist, or granisetron + mCPBG was given intraperitoneally." | 5.36 | Granisetron ameliorates acetic acid-induced colitis in rats. ( Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mousavizadeh, K; Rahimian, R; Rasouli, MR, 2010) |
| "Visceral pain is one of the most common forms of pain and for which new drugs would be welcome." | 5.35 | Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice. ( Meymandi, MS; Sepehri, G, 2008) |
| "Propionic acid (PPA) is a short chain fatty acid, a metabolic end-product of enteric bacteria in the gut, and a common food preservative." | 5.35 | Intracerebroventricular injection of propionic acid, an enteric bacterial metabolic end-product, impairs social behavior in the rat: implications for an animal model of autism. ( Cain, DP; MacFabe, DF; Ossenkopp, KP; Scratch, S; Shultz, SR; Taylor, R; Whelan, J, 2008) |
| "Gastric ulcer is a source of visceral pain." | 5.33 | Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006) |
| "Gastric ulcers were induced by luminal application of 60% acetic acid under surgical conditions." | 5.33 | Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006) |
| "Acetic acid (AcOH), which is a short-chain fatty acid, is reported to have some beneficial effects on metabolism." | 5.33 | Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice. ( Kadowaki, T; Oshima, Y; Sakakibara, S; Tsukamoto, Y; Yamauchi, T, 2006) |
| "Colitis was induced by intracolonic injection of 3% acetic acid." | 5.32 | Thymoquinone protects against experimental colitis in rats. ( Mahgoub, AA, 2003) |
| "Colitis was induced by intrarectal administration of acetic acid and followed over a period of seven days." | 5.31 | Blood purine and energy status in rats with colitis. ( Al-Awadi, FM; Khan, I, 2001) |
| "In acetic acid-treated rats, this activity increased to 2." | 5.30 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
| "Gastric ulcer was induced by injecting 20 microliters glacial acetic acid into gastric wall of rat stomachs." | 5.30 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
| "Acetic acid colitis was induced 24 hr before enzyme inhibition began." | 5.29 | Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats. ( Guth, E; Guth, PH; LeDuc, LE; Reedy, T; Su, KC, 1993) |
| " Chronic administration of hydrocortisone sodium phosphate resulted in a significant delay of ulcer healing induced by acetic acid." | 5.28 | Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991) |
| "Chronic gastric ulcers were produced in male Wistar rats, weighing 180 g, by the application of 100% acetic acid." | 5.28 | Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991) |
| "Fifty rats were randomly separated into five groups (n = 10) with different durations (30 s, 5, 10, and 20 min) of exposure of the colon to 4% acetic acid and colitis was investigated for 0-9 days." | 4.12 | Improving Animal Model of Induced Colitis by Acetic Acid in Terms of Fibrosis and Inflammation Incidence in the Colon. ( Babaei, A; Bahrami, G; Madani, H; Malekshahi, H; Miraghaee, S, 2022) |
| " The anthocyanidin effects were examined in gastric ulcer mouse models induced by ethanol, non-steroidal anti-inflammatory drugs (NSAIDs), ischemia-reperfusion (IR), acetic acid and duodenal ulcer induced by polypharmacy." | 4.02 | Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation. ( Dos Santos, RC; Fagundes, FL; Pereira, QC; Zarricueta, ML, 2021) |
| " The effect of the extract on acute inflammation was analyzed by increasing vascular permeability via acetic acid and xylene induced ear edema among mice." | 4.02 | Effect of Nectaroscordum koelzi Methanolic Extract on Acute and Chronic Inflammation in Male Mice. ( Alipour, M; Hasanvand, KH; Khaksarian, M; Mahmoudvand, H; Nadri, S; Naizi, M, 2021) |
| "The findings showed that the extract was effective on acute inflammation induced by acetic acid in mice." | 4.02 | Effect of Nectaroscordum koelzi Methanolic Extract on Acute and Chronic Inflammation in Male Mice. ( Alipour, M; Hasanvand, KH; Khaksarian, M; Mahmoudvand, H; Nadri, S; Naizi, M, 2021) |
| "The results showed that physalin A inhibited carrageenan-induced paw edema of rats and capillary permeability of mice induced by acetic acid in vivo." | 4.02 | Anti-inflammatory action of physalin A by blocking the activation of NF-κB signaling pathway. ( Gu, J; Li, D; Li, H; Liu, P; Liu, Y; Mou, X; Qiu, F; Wang, L; Zhang, Q; Zhao, F; Zong, M, 2021) |
| " The effect of the extract in three additional in vivo models were studied: intestinal motility and diarrhea induced by ricin oil, and visceral pain induced by intracolonic administration of capsaicin." | 4.02 | Pharmacologycal activity of peperina (Minthostachys verticillata) on gastrointestinal tract. ( Bach, H; Carranza, A; Gorzalczany, SB; Rodríguez Basso, A; Zainutti, VM, 2021) |
| " erectum at doses of 200, 100, and 50 mg/kg and four major constituents (20, 21, 22, and 27) at doses of 100 and 50 mg/kg delivered via intragastrical administration were evaluated using carrageenan-induced paw edema and acetic acid-stimulated writhing animal models." | 4.02 | Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum. ( Liu, YP; Luo, XD; Qin, XJ; Yang, XW; Yuan, HL; Zhao, YL, 2021) |
| " erectum ameliorated the paw edema by carrageenan-stimulated and reduced the number of writhing by acetic acid-induced in mice compared to the model group, with the AL fraction showing the most potent effects." | 4.02 | Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum. ( Liu, YP; Luo, XD; Qin, XJ; Yang, XW; Yuan, HL; Zhao, YL, 2021) |
| " trimera (EOBT) against gastric ulcer lesions caused by absolute ethanol and acetic acid, respectively, and to identify the mechanism of action of this essential oil in male Wistar rats." | 4.02 | The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity. ( Assunção, R; Besten, MA; Bueno, G; Chavez Rico, SL; Emílio-Silva, MT; Heiden, G; Hiruma-Lima, CA; Justulin, LA; Lima Camargo, AC; Machado da Rocha, LR; Nunes, DS; Ohara, R; Périco, LL; Rodrigues, VP, 2021) |
| " AiME showed significant dose-dependent analgesic activity against acetic acid-induced writhing, formalin-induced paw licking, and hot plate pain model." | 4.02 | Pharmacological investigation of analgesic and antipyretic activities of methanol extract of the whole part of Aeginetia indica. ( Abeer, M; Ahmed, J; Barek, MA; Haque, ME; Jafrin, S; Jashimuddin, M; Naznin, NE; Reza, MS; Ud Daula, AFMS, 2021) |
| " To evaluate the analgesic effects of AC, 4 different pain models including hot plate assay, acetic acid writhing assay, formalin and CFA induced pain models were adopted in this study." | 4.02 | Comparison of analgesic activities of aconitine in different mice pain models. ( Chen, J; Deng, J; Feng, Q; Han, J; Huang, Q; Leung, EL; Liu, Z; Lu, L; Qi, X; Wang, D; Wang, Y; Zhang, Y, 2021) |
| " The acetylcholinesterase inhibitor (ACHEI); neostigmine, is known clinically for its analgesic effect in the perioperative phases proving high efficacy; besides possessing anti-inflammatory properties controlling immune cells and cytokine level." | 4.02 | The effective interplay of (non-) selective NSAIDs with neostigmine in animal models of analgesia and inflammation. ( Abdel-Bary, A; El-Tahan, RA; Gowayed, MA, 2021) |
| " speciosa accelerated healing of gastric ulcers even in presence of indomethacin, while decreasing bacterial loads in rats' stomachs." | 4.02 | Eremomastax speciosa (Hochst.) Cufod. counteracts the delaying effect of indomethacin on Helicobacter pylori-associated chronic gastric ulcers healing. ( Amang, AP; Choudhary, MI; Enow-Orock, GE; Maharjan, R; Mezui, C; Siwe, GT; Tan, PV; Zondegoumba, NE, 2021) |
| " The objective of this experiment is to investigate the protective effects of modafinil on colitis induced by acetic acid in rat and the involvement of nitric oxide pathway." | 3.96 | Biochemical and histopathological evidence for the beneficial effects of modafinil on the rat model of inflammatory bowel disease: involvement of nitric oxide pathway. ( Dehpour, AR; Dejban, P; Rahimi, N; Takzare, N, 2020) |
| "Colitis was induced by intra-rectal instillation of 1 ml acetic acid (4%)." | 3.96 | Biochemical and histopathological evidence for the beneficial effects of modafinil on the rat model of inflammatory bowel disease: involvement of nitric oxide pathway. ( Dehpour, AR; Dejban, P; Rahimi, N; Takzare, N, 2020) |
| "While induction of colitis caused severe macroscopic lesions, administration of dexamethasone and modafinil (100 and 150 mg/kg) significantly improved macroscopic ulcers." | 3.96 | Biochemical and histopathological evidence for the beneficial effects of modafinil on the rat model of inflammatory bowel disease: involvement of nitric oxide pathway. ( Dehpour, AR; Dejban, P; Rahimi, N; Takzare, N, 2020) |
| "It was shown that finasteride, a 5α-reductase inhibitor (50 mg/kg, intraperitoneally) produced analgesic and antiexudative effects in experimental peritonitis induced by intraperitoneal injection of 1% acetic acid." | 3.96 | Antiexudative Effects of Finasteride and a New Pyrazolo[C]Pyridine Derivative GIZh-72 in Acetic Acid-Induced Experimental Peritonitis. ( Ivanova, EA; Kalinina, TS; Kudryashov, NV; Kurshin, AA; Shimshirt, AA; Voronina, TA; Zhmurenko, LA, 2020) |
| "25% acetic acid irrigation to mitigate nasal BB injury appears to be ineffective in reducing the full-thickness mucoperichondrial necrosis starting within 3 h." | 3.96 | A potential post-removal pH neutralization strategy to mitigate nasal button battery injuries. ( Bakırtaş, M; Sancaktar, ME, 2020) |
| "3 V lithium BBs were placed on the cadaveric sheep nasal septum model segments." | 3.96 | A potential post-removal pH neutralization strategy to mitigate nasal button battery injuries. ( Bakırtaş, M; Sancaktar, ME, 2020) |
| "The phosphodiesterase-3 inhibitor, cilostazol has been recently shown to protect against chemically induced colitis in animal models." | 3.96 | Cilostazol protects against acetic acid-induced colitis in rats: Possible role for cAMP/SIRT1 pathway. ( Elhassanny, AEM; Elshazly, SM; Mahmoud, NM, 2020) |
| " An acetic acid-induced colitis model was produced in groups 2, 3 and 4 and was administered normal saline, topical GO and topical and systemic GO, respectively." | 3.96 | Effects of garlic oil (allium sativum) on acetic acid-induced colitis in rats: Garlic oil and experimental colitis. ( Can, M; Kılınç, F; Köktürk, F; Şen Tanrıkulu, C; Tanrıkulu, Y, 2020) |
| "GO can reduce colonic damage and inflammation in the acetic acid-induced colitis model, with effects on both local and systemic treatments, but with a more pronounced effect in local treatment." | 3.96 | Effects of garlic oil (allium sativum) on acetic acid-induced colitis in rats: Garlic oil and experimental colitis. ( Can, M; Kılınç, F; Köktürk, F; Şen Tanrıkulu, C; Tanrıkulu, Y, 2020) |
| " The plant extract at doses of 50, 100 and 150 mg/kg was tested for anti-inflammatory activity against carrageenan and egg albumin induced paw edema in mice and analgesic activity was appraised against acetic acid induced writhing and formalin induced paw licking in mice models." | 3.96 | Evaluation of anti-inflammatory and analgesic activities of aqueous methanolic extract of Ranunculus muricatus in albino mice. ( Alamgeer, -; Asif, H; Hasan, UH; Irfan, HM; Nasreen, P; Sharif, A; Uttra, AM; Younis, W, 2020) |
| "Esophageal ulcers were induced in rats by topical exposure of the lower esophageal serosa to acetic acid, followed by intraperitoneal administration of HGF (200 µg/day) using an osmotic pump for 7 days." | 3.91 | Hepatocyte Growth Factor Facilitates Esophageal Mucosal Repair and Inhibits the Submucosal Fibrosis in a Rat Model of Esophageal Ulcer. ( Arima, S; Hashimoto, S; Ido, A; Kanmura, S; Komaki, Y; Maeda, H; Mawatari, S; Nasu, Y; Oda, K; Sasaki, F; Tanoue, S; Tsubouchi, H, 2019) |
| ") administration of acetic acid, a well-established protocol for visceral pain in rodents." | 3.91 | Understanding nociception-related phenotypes in adult zebrafish: Behavioral and pharmacological characterization using a new acetic acid model. ( Costa, FV; Kalueff, AV; Quadros, VA; Rosa, LV; Rosemberg, DB; Santos, ARS, 2019) |
| " Enhanced analgesic and anti-inflammatory activity was observed with S-SMEDD formulations in acetic acid-induced writhings and carrageenan-induced paw edema models, respectively." | 3.91 | Mefenamic acid-loaded solid SMEDDS: an innovative aspect for dose reduction and improved pharmacodynamic profile. ( Bedi, N; Kumar, M; Singh, D, 2019) |
| "It is aimed to investigate the possible contribution of cannabinoid system that supresses the nociceptive process by the activation of CB1 and CB2 receptors in central and peripheral levels of pain pathways, to the analgesic activity of protocatechuic acid." | 3.91 | Cannabinoid system involves in the analgesic effect of protocatechuic acid. ( Arslan, R; Bektas, N; Dikmen, DY; Okcay, Y, 2019) |
| " To assess the usefulness of this model for testing potential analgesics, three known synthetic pain medications were assessed (ibuprofen, acetaminophen and tramadol) along with three naturally occurring products (honokiol, tetrahydrocannabinol and cannabidiol)." | 3.88 | Comparison of cannabinoids with known analgesics using a novel high throughput zebrafish larval model of nociception. ( Achenbach, JC; Berrue, F; Ellis, LD; Hill, J; McDougall, JJ; Morash, M, 2018) |
| " On the other hand, acetic acid-induced writhes indicate visceral pain features of IBS model animals." | 3.88 | Involvement of peripheral alpha2A adrenoceptor in the acceleration of gastrointestinal transit and abdominal visceral pain induced by intermittent deprivation of REM sleep. ( Endo, S; Kozawa, M; Murakami, H; Muto, M; Tadano, T; Tan-No, K; Tsuchiya, M; Yaoita, F, 2018) |
| " Interestingly, the acid-induced trigeminal pain behaviour was inhibited by amiloride, an antagonist of acid-sensing ion channels (ASICs), but not by AMG-9810, an inhibitor of transient receptor potential cation channel V1(TRPV1)." | 3.88 | Increased Asics Expression via the Camkii-CREB Pathway in a Novel Mouse Model of Trigeminal Pain. ( Fu, X; Huang, L; Lu, Z; Wang, X; Wang, Y; Xiao, Z; Zhu, F, 2018) |
| "In this rat study involving males, intact (cycling) females, and ovariectomized females, gastric ulcers were induced using acetic acid." | 3.88 | Sex-specific effects of ( Bueno, G; Camargo, ACL; da Rocha, LRM; da Silva, LM; de Andrade, SF; Dos Santos, C; Dos Santos, RC; Hiruma-Lima, CA; Justulin Júnior, LA; Nunes, VVA; Ohara, R; Périco, LL; Rodrigues, VP; Steimbach, VMB; Vilegas, W, 2018) |
| "Here, we found that intratesticular bradykinin evokes pain behavior via stimulation of bradykinin B2 receptors and that intratesticular acetic acid injection induces intratesticular bradykinin synthesis, consequently leading to pain behavior." | 3.88 | Intratesticular Bradykinin Involvement in Rat Testicular Pain Models. ( Fujimoto, K; Masuda, N; Takeda, M; Yoshino, T; Yoshioka, K; Yuyama, H, 2018) |
| "To clarify the role of bradykinin in urogenital pain, we investigated bradykinin involvement in rat models of testicular pain." | 3.88 | Intratesticular Bradykinin Involvement in Rat Testicular Pain Models. ( Fujimoto, K; Masuda, N; Takeda, M; Yoshino, T; Yoshioka, K; Yuyama, H, 2018) |
| "An injection of bradykinin into the testes of conscious rats induced pain behaviors that were dose-proportionally reduced by prior administration of FK3657." | 3.88 | Intratesticular Bradykinin Involvement in Rat Testicular Pain Models. ( Fujimoto, K; Masuda, N; Takeda, M; Yoshino, T; Yoshioka, K; Yuyama, H, 2018) |
| "The purpose of our investigative work has been to determine whether there can be therapeutic roles in the administration of sildenafil citrate, heparin and several neuropeptides on an animal model where gastric ulcers were induced with acetic acid, and to compare their efficacy." | 3.85 | Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017) |
| "Overall the data indicate that low dose heparin, and especially sildenafil citrate and neuropeptides, can be used clinically as an alternative approach in the treatment of the gastric ulcer." | 3.85 | Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017) |
| ""Unhealed gastric ulcers" were induced using indomethacin following the establishment of acetic-acid-induced chronic gastric ulcers." | 3.85 | Healing and Antisecretory Effects of Aqueous Extract of ( Amang, AP; Emakoua, J; Enow-Orock, GE; Mbah, G; Mezui, C; Nkwengoua, EZ; Siwe, GT; Tan, PV, 2017) |
| "The extract was assessed for antinociceptive activity using chemical and heat induced pain models such as hot plate, tail immersion, acetic acid-induced writhing, formalin, glutamate, and cinnamaldehyde test models in mice at the doses of 100, 200, and 400 mg/kg (p." | 3.85 | Antinociceptive effect of methanol extract of Dalbergia sissoo leaves in mice. ( Khan, MF; Khatun, A; Mannan, MA, 2017) |
| "05) suppressed topical ear edema, systemic paw edema, global edematous response to formaldehyde arthritis and granuloma tissue growth." | 3.83 | Extracts of Leptadenia hastata Leaf, a Famine Food and Traditional Remedy for Furuncles, Suppress Inflammation in Murine Models. ( Akah, PA; Ezea, SC; Ezike, AC; Okoli, CO; Ufere, IK, 2016) |
| " This study investigates the ameliorative effect of Ocimum basilicum essential oil on an acetic acid-induced colitis model in rats." | 3.83 | Protective Effect of Ocimum basilicum Essential Oil Against Acetic Acid-Induced Colitis in Rats. ( Ghannadi, AR; Mehrzadi, S; Minaiyan, M; Rashidian, A; Roohi, P, 2016) |
| "The analgesic effects on pain-related behaviors following the topical application of hangeshashinto were evaluated in an oral ulcer rat model treated with acetic acid using recently developed methods." | 3.83 | The traditional Japanese medicine hangeshashinto alleviates oral ulcer-induced pain in a rat model. ( Hattori, T; Hitomi, S; Imai, R; Inenaga, K; Kase, Y; Kubota, K; Omiya, Y; Ono, K; Terawaki, K; Yamaguchi, K, 2016) |
| "This study aimed to investigate the involvement of opioid receptors in the systemic and peripheral antinociceptive activities of montelukast in different animal models of pain." | 3.83 | Involvement of opioid receptors in the systemic and peripheral antinociceptive actions of montelukast in the animal models of pain. ( Alboghobeish, S; Ghorbanzadeh, B; Mansouri, MT; Sahraei, H, 2016) |
| " regia ethanol extract and its active constituent β-Elemene with special interest in inflammation model using standard in vivo anti-inflammatory models: Carrageenan-induced paw edema, Cotton pellet granuloma, and Acetic acid-induced vascular permeability." | 3.83 | Anti-inflammatory effects of royal poinciana through inhibition of toll-like receptor 4 signaling pathway. ( Meenu, M; Muthuraman, MS; Patra, S; Pemaiah, B; Priya, P, 2016) |
| " Acetic acid-induced writhing test and carrageenan-induced paw edema model were used for evaluation." | 3.83 | Studies on anti-inflammatory and analgesic properties of Lactobacillus rhamnosus in experimental animal models. ( Amdekar, S; Singh, V, 2016) |
| " rhamnosus suppressed carrageenan-induced paw edema after second phase and decreased the acetic acid-induced writhings." | 3.83 | Studies on anti-inflammatory and analgesic properties of Lactobacillus rhamnosus in experimental animal models. ( Amdekar, S; Singh, V, 2016) |
| "76% and 84% pain relief in acetic acid induced writhing test at 100 mg/kg i." | 3.83 | Antinociceptive, antioxidant and phytochemical studies of Pakistani medicinal plants. ( Khan, H; Rauf, A; Siddiqui, BS; Uddin, G; Ullah, R, 2016) |
| "This study aimed to evaluate potential protecting effect of ML and its major constituent, eucalyptol, against acetic acid-induced colitis in rats, a model of human inflammatory bowel disease (IBD)." | 3.83 | Mentha longifolia protects against acetic-acid induced colitis in rats. ( Abdallah, HM; Ali, SS; Murad, HA, 2016) |
| "Rats were divided into ten groups (n=8) given orally for three days (mg/kg/day) the following: normal control, acetic acid-induced colitis (un-treated, positive control), vehicle (DMSO), sulfasalazine (500), ML extract (100, 500, 1000), and eucalyptol (100, 200, 400)." | 3.83 | Mentha longifolia protects against acetic-acid induced colitis in rats. ( Abdallah, HM; Ali, SS; Murad, HA, 2016) |
| "ML (in moderate doses) and eucalyptol (dose-dependently) exerted protective effects against acetic acid-induced colitis in rats possibly through antioxidant and antiinflammatory properties suggesting a potential benefit in treatments of IBD." | 3.83 | Mentha longifolia protects against acetic-acid induced colitis in rats. ( Abdallah, HM; Ali, SS; Murad, HA, 2016) |
| " The hot plate test and acetic acid-induced writhing assay in Kunming mice were adopted to evaluate the pain-relieving effects of BLG." | 3.83 | Anti-inflammatory and analgesic effects of Bi-yuan-ling granules. ( Chen, XB; Dai, K; He, F; Liu, HX; Ren, YS; Su, HW; Xiang, MX; Yin, X, 2016) |
| " The gastroprotective and ulcer healing activities of HEPu were evaluated using acidified ethanol (acute) and acetic acid (chronic) gastric ulcer models in rodents." | 3.83 | Piper umbellatum L.: A medicinal plant with gastric-ulcer protective and ulcer healing effects in experimental rodent models. ( Balogun, SO; da Silva Junior, IF; Damazo, AS; de Oliveira, RG; Martins, DTO, 2016) |
| " Materials and methods Analgesic and anti-inflammatory activities of ISA were evaluated using writhing, hot plate, xylene-induced ear oedema, carrageenan-induced paw oedema and cotton pellets-induced granuloma test, meanwhile the prostaglandin E2 (PGE2) and malondialdehyde (MDA) levels were assessed in the oedema paw tissue." | 3.83 | Anti-inflammatory, analgesic and antioxidant activities of 3,4-oxo-isopropylidene-shikimic acid. ( Dong, K; Sun, JY; Xing, JF; You, CY; You, HS, 2016) |
| " Analgesic activity using acetic acid induced writhing and formalin test in mice, anti-inflammatory activity using carrageenan induced paw oedema and acetic acid-induced vascular permeability in mice, and antipyretic activity using Brewer's yeast induced pyrexia in rats were evaluated at 100mg/kg, 200mg/kg, and 400mg/kg doses of the extract." | 3.83 | Anti-oxidant, anti-inflammatory, analgesic and antipyretic activities of grapevine leaf extract (Vitis vinifera) in mice and identification of its active constituents by LC-MS/MS analyses. ( Aouey, B; Bouaziz, M; Fetoui, H; Samet, AM; Simmonds, MSJ, 2016) |
| "The model of gastric ulcer was imitated by acetic acid in rats, and AL was gavaged." | 3.81 | Comparison of the anti-ulcer activity between the crude and bran-processed Atractylodes lancea in the rat model of gastric ulcer induced by acetic acid. ( Cai, Q; Jia, TZ; Jiang, N; Ma, MY; Min, DY; Yu, Y; Yuan, Y, 2015) |
| " There is no study showing the efficacy of fostamatinib, with proven effects on some inflammatory diseases, on ulcerative colitis." | 3.81 | The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis. ( Aksit, H; Ayvaz, S; Can, G; Can, H; Demirtas, S; Karaca, T; Korkmaz, U; Kurt, M; Yilmaz, B, 2015) |
| "The study included 28 male Sprague-Dawley rats, randomly divided into control group, fostamatinib group, colitis group and fostamatinib + colitis group, each containing seven rats." | 3.81 | The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis. ( Aksit, H; Ayvaz, S; Can, G; Can, H; Demirtas, S; Karaca, T; Korkmaz, U; Kurt, M; Yilmaz, B, 2015) |
| "Fostamatinib reduced the inflammatory damage in the experimental colitis." | 3.81 | The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis. ( Aksit, H; Ayvaz, S; Can, G; Can, H; Demirtas, S; Karaca, T; Korkmaz, U; Kurt, M; Yilmaz, B, 2015) |
| " Xylene-induced ear edema, carrageenan-induced paw edema and acetic acid-induced vascular permeability test were used to investigate the anti-inflammatory activities of GL in mice." | 3.81 | Observing Anti-inflammatory and Anti-nociceptive Activities of Glycyrrhizin Through Regulating COX-2 and Pro-inflammatory Cytokines Expressions in Mice. ( Li, YX; Ma, L; Niu, Y; Niu, YT; Shi, GJ; Sun, T; Wang, HL; Wu, J; Yu, JQ; Zheng, J, 2015) |
| " The present study evaluated the effects of an experimentally induced acute pain state (acetic acid injections) on the potency of morphine and oxycodone to produce discriminative stimulus effects in male and female C57Bl/6 mice trained to discriminate 3." | 3.81 | Discriminative stimulus effects of morphine and oxycodone in the absence and presence of acetic acid in male and female C57Bl/6 mice. ( Neelakantan, H; Walker, EA; Ward, SJ, 2015) |
| " Additionally, anti-inflammatory function of gelsolin (8 mg/mouse) compared with anti-inflammatory drug diclofenac sodium (10 mg/kg)] was confirmed in the carrageenan injection induced paw edema where latter was measured by vernier caliper and fluorescent tomography imaging." | 3.81 | Analgesic and Anti-Inflammatory Properties of Gelsolin in Acetic Acid Induced Writhing, Tail Immersion and Carrageenan Induced Paw Edema in Mice. ( Chopra, BS; Choudhary, V; Garg, R; Gupta, AK; Khatri, N; Parasar, D; Sagar, A, 2015) |
| " The present study tested the hypothesis that dietary TBU supplementation could alleviate intestinal injury in the acetic acid (ACA)-induced porcine model of colitis." | 3.80 | Dietary supplementation with tributyrin alleviates intestinal injury in piglets challenged with intrarectal administration of acetic acid. ( Chen, X; Ding, B; Gong, J; Hou, Y; Liu, Y; Wang, L; Wang, Q; Wu, G; Yi, D; Yin, Y; Zhu, H, 2014) |
| " δ-Amyrone also decreased the level of nitric oxide (NO), prostaglandin E2 (PGE2), interleukin-6 (IL-6) and leukocyte numbers in acetic acid-induced peritonitis in vivo." | 3.80 | δ-Amyrone, a specific inhibitor of cyclooxygenase-2, exhibits anti-inflammatory effects in vitro and in vivo of mice. ( Hu, H; Huang, H; Li, H; Li, W; Li, Y; Mu, Q; Niu, X; Yao, H, 2014) |
| " We investigated the antinociceptive effect of botulinum toxin type A (BTX-A) in male Wistar rats in two models of visceral pain: peritonitis induced by intraperitoneal injection of 1% acetic acid and colitis induced by intracolonic instillation of 0." | 3.80 | Antinociceptive effect of botulinum toxin type A on experimental abdominal pain. ( Babić, A; Bach-Rojecky, L; Drinovac, V; Lacković, Z, 2014) |
| " Opioid coadministration had a synergistic effect in the acute tonic pain (acetic acid writhing test), acute phasic pain (tail flick test) and inflammatory pain (orofacial formalin test)." | 3.79 | Systemic synergism between codeine and morphine in three pain models in mice. ( Miranda, HF; Noriega, V; Prieto, JC; Sierralta, F; Zepeda, RJ, 2013) |
| " AT and 6-HL exhibited anti ulcer activity in experimentally induced ulcer models including cold restraint stress (CRU), alcohol (AL), pylorus ligation-induced gastric ulcer (PL) models and they also showed ulcer healing effect in chronic acetic acid-induced ulcer model (AC)." | 3.79 | Arbortristoside-A and 7-O-trans-cinnamoyl-6β-hydroxyloganin isolated from Nyctanthes arbortristis possess anti-ulcerogenic and ulcer-healing properties. ( Barthwal, MK; Mishra, V; Narender, T; Palit, G; Pandeti, S; Pandey, HP; Shukla, A, 2013) |
| "The administration of acetic acid induced acute rat UC, as indicated by diarrhea, weight loss, and colonic mucosal damage." | 3.79 | Protective effects of hydrogen-rich saline on ulcerative colitis rat model. ( He, J; Mei, X; Sun, A; Sun, X; Wang, J; Wang, Q; Xiong, S; Zhang, C; Zhang, J, 2013) |
| "We investigated the regulation of urinary bladder function by electrical stimulation of the L6 spinal nerve (SN) using cystometry in normal rats and in rats with cystitis induced by intravesical infusion of dilute acetic acid." | 3.79 | Neuromodulation attenuates bladder hyperactivity in a rat cystitis model. ( Nelson, DE; Nickles, A; Su, X, 2013) |
| "The effect of fumonisin B1, an inhibitor of ceramide synthase, and of d,l,-threo-1-phenyl-2-hexadecanoylamino-3-morpholino-1-propanol (PPMP) and N-butyldeoxynojirimycin (NB-DNJ), both inhibitors of glucosylceramide synthase, on the accumulation of ceramide and formation of gastric ulcer were examined in the rat model of acetic acid-induced gastric ulcer." | 3.79 | Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. ( Hibi, T; Miura, S; Mizushima, T; Nagata, H; Nakashita, M; Suzuki, H; Taki, T; Uehara, K, 2013) |
| "Fumonisin B1 attenuated acetic acid-induced gastric ulcer formation, associated with a decrease in the number of apoptotic cells." | 3.79 | Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. ( Hibi, T; Miura, S; Mizushima, T; Nagata, H; Nakashita, M; Suzuki, H; Taki, T; Uehara, K, 2013) |
| "To measure the effects of nonhypercalcemic vitamin D receptor agonist elocalcitol on bladder function in rats with cyclophosphamide-induced cystitis and on bladder function and sensory nerve activity in a mouse with acetic acid-evoked bladder irritation." | 3.79 | Effects of vitamin D analog on bladder function and sensory signaling in animal models of cystitis. ( Redman, TL; Shapiro, B; Zvara, P, 2013) |
| "To elucidate the ameliorative effect of hydroalcoholic extract of leaves of Hibiscus rosa sinensis (HRS) in acetic acid induced experimental colitis in male wistar rats." | 3.78 | Effect of hydroalcoholic extract of Hibiscus rosa sinensis Linn. leaves in experimental colitis in rats. ( Badole, SL; Bodhankar, SL; Ghosh, P; Ghule, AE; Gosavi, TP; Kandhare, AD; Raygude, KS, 2012) |
| " The animals were randomly divided into Patrinia villosa group (PV group), dexamethasone group (DEX group), and model-control group (CON group) to perform an ear edema test, a carrageenin-induced paw edema test, a cotton pellet-induced granuloma formation test, and an acetic acid-induced writhing test." | 3.78 | The anti-inflammatory and anti-nociceptive activities of Patrinia villosa and its mechanism on the proinflammatory cytokines of rats with pelvic inflammation. ( Huang, Y; Jin, Y; Xia, YX; Xu, ST; Zheng, Y; Zhu, HB, 2012) |
| "The anti-inflammatory property of CPZ on acute inflammation was evaluated by inflammatory models of dimethylbenzene (DMB)-induced ear vasodilatation and acetic acid-induced capillary permeability enhancement in mice, as well as the carrageenan-induced paw edema rat model, in which inflammation-related cytokine including prostaglandin E(2) (PGE(2)), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and nitric oxide (NO) in the edematous paw tissue were determined by enzyme linked immunosorbent assay (ELISA)." | 3.78 | Experimental study on anti-inflammatory activity of a TCM recipe consisting of the supercritical fluid CO2 extract of Chrysanthemum indicum, Patchouli Oil and Zedoary Turmeric Oil in vivo. ( Lai, P; Lai, XP; Liang, HC; Qin, Z; Su, JY; Su, ZR; Tan, LR; Ye, MR, 2012) |
| "This study describes the antinociceptive effects of μ-opioid agonists, d-Ala(2),N-Me-Phe(4),Gly(5)-ol-enkephalin (DAMGO) and morphine in a model of rat visceral pain in which nociceptive responses were triggered by 2% acetic acid intraperitoneal (i." | 3.78 | The central versus peripheral antinociceptive effects of μ-opioid receptor agonists in the new model of rat visceral pain. ( Al-Khrasani, M; Fürst, S; Király, K; Lackó, E; Mousa, S; Riba, P; Schäfer, M; Sobor, M; Timár, J, 2012) |
| "The results suggest that the methanolic extract of Cyathula prostrata possesses anti-inflammatory and analgesic activities and this authenticates the use of the plant in the traditional treatment of ailments associated with inflammation and pain." | 3.78 | Antiinflammatory, analgesic and antioxidant activities of Cyathula prostrata (Linn.) Blume (Amaranthaceae). ( Ibrahim, B; Sowemimo, A; Van de Venter, M; van Rooyen, A, 2012) |
| "To evaluate the antioxidant effect of an extract of the plant Boswellia serrata in an experimental model of acute ulcerative colitis induced by administration of acetic acid (AA) in rats." | 3.78 | Effect of Boswellia serrata on antioxidant status in an experimental model of colitis rats induced by acetic acid. ( Fillmann, HS; Hartmann, RM; Marroni, NP; Morgan Martins, MI; Tieppo, J, 2012) |
| " Carrageenan induced paw edema model was used for anti-inflammatory and acetic acid induced model used for analgesic activity." | 3.78 | Anti-inflammatory and analgesic potential of a novel steroidal derivative from Bryophyllum pinnatum. ( Afzal, M; Afzal, O; Alam, J; Anwar, F; Gupta, G; Gupta, R; Hakeem, KR; Kazmi, I; Pravez, M; Rahman, M, 2012) |
| "Application of acetic acid topically to the mucosal or serosal side of the stomach has been well used to create a chronic gastric ulcer model." | 3.78 | Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model. ( Cao, H; Chen, D; Johannessen, H; Kodama, Y; Okabe, S; Takahashi, R; Wang, TC; Zhao, CM, 2012) |
| " Severe necrosis in the cancer was observed in the side exposing to acetic acid, but not in the control side, shortly after the treatment (i." | 3.78 | Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model. ( Cao, H; Chen, D; Johannessen, H; Kodama, Y; Okabe, S; Takahashi, R; Wang, TC; Zhao, CM, 2012) |
| "Topical application of acetic acid either from mucosal or serosal surface promptly caused the necrosis of tumor, suggesting the potential approach of this simple and reliable method as a cytoreductive treatment of gastric cancer in patients through endoscopy or laparoscopy." | 3.78 | Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model. ( Cao, H; Chen, D; Johannessen, H; Kodama, Y; Okabe, S; Takahashi, R; Wang, TC; Zhao, CM, 2012) |
| " Nevertheless, the anti-inflammatory activity was tested in carrageenan induced paw edema and histamine induced inflammatory tests." | 3.78 | Antipyretic, analgesic and anti-inflammatory activity of Viola betonicifolia whole plant. ( Khan, H; Muhammad, N; Saeed, M, 2012) |
| " Similarly carrageenan and histamine induces inflammation was significantly antagonized by VBME, 66." | 3.78 | Antipyretic, analgesic and anti-inflammatory activity of Viola betonicifolia whole plant. ( Khan, H; Muhammad, N; Saeed, M, 2012) |
| "The preventive and healing properties of Croton urucurana bark methanol extract (CUE) were evaluated in experimental models of acute (ethanol and indomethacin) and chronic (acetic acid) gastric ulcers." | 3.78 | Antiulcerogenic effect of Croton urucurana Baillon bark. ( Aparecida Pinto, L; de Cássia Freitas, K; Faloni de Andrade, S; Leite Kassuya, CA; Nazari Formagio, AS; Wolff Cordeiro, K, 2012) |
| " We have investigated the behavioural effects of carvacrol in animal models of pain, such as acetic acid-induced abdominal constriction, formalin and hot-plate tests in mice." | 3.78 | Antinociceptive activity of carvacrol (5-isopropyl-2-methylphenol) in mice. ( Cavalcante Melo, FH; Citó, Mdo C; de Sousa, DP; de Sousa, FC; de Vasconcelos, SM; Fernandes, ML; Rios, ER; Rocha, NF, 2012) |
| "The protective effects of a complex glycosaminoglycan preparation in doses of 50 and 100 mg/kg were studied in experimental cystitis induced in rats by administration of 9% acetic acid." | 3.78 | Effects of exogenous glycosaminoglycans on the histological structure of the rat bladder in experimental cystitis. ( Sobolev, VE, 2012) |
| "Colitis was induced by intracolonic administration of acetic acid." | 3.77 | The effect of exopolysaccharide-producing probiotic strains on gut oxidative damage in experimental colitis. ( Aslım, B; Demirbağ, AE; Işık, S; Sengül, N; Uçar, G, 2011) |
| "Significant oxidative damage was associated with a higher level of malondialdehyde (MDA) activity and reduced antioxidant enzyme activities in the colitis model group." | 3.77 | The effect of exopolysaccharide-producing probiotic strains on gut oxidative damage in experimental colitis. ( Aslım, B; Demirbağ, AE; Işık, S; Sengül, N; Uçar, G, 2011) |
| " The pharmacological activity of AFE and pure scopoletin at the same equivalent dose present in AFE was investigated in rat on gastro-esophageal inflammatory models (acid reflux esophagitis, acute gastritis induced by ethanol and serotonin, and chronic gastric ulcer induced by acetic acid); gastric biochemical parameters and gastrointestinal motility." | 3.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
| "50 g/kg) significantly prevented the formation of acid reflux esophagitis, reduced the formation of ethanol-induced acute gastric lesions, suppressed the development of gastric lesions in response to serotonin, and accelerated the healing of acetic acid-induced chronic gastric ulcer in rats with equal potency to those obtained by standard antisecretory agents (ranitidine and lansoprazole)." | 3.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
| " (Rubiaceae) fruit, commonly known as "Noni", in an aqueous extract preparation (AFE) as used in Thai traditional medicine and its biomarker scopoletin on gastro-esophageal inflammatory models that are related to the claimed pharmacological properties of AFE and/or resembled the human esophagitis or gastric ulcer." | 3.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
| "To evaluate the antinociceptive effect of Emilia sonchifolia hydroethanolic extract (EsHE) administered by oral route, peripheral (acetic acid-induced abdominal writhing and formalin), spinal (tail flick) and supra-spinal (hot plate) behavioral models of acute pain were used." | 3.77 | Antinociceptive effect of extract of Emilia sonchifolia in mice. ( Couto, VM; Dias, DF; Dos Santos, MH; Giusti-Paiva, A; Nascimento, CG; Soncini, R; Vilela, FC, 2011) |
| " (Plantaginaceae) on gastric secretion and cytoprotection was evaluated using different models of gastroduodenal ulcer, including acetic acid induced chronic gastric ulcer, indomethacin induced gastric ulcer, cysteamine induced duodenal ulcer and pylorus ligation induced gastric ulcer." | 3.77 | Evaluation of the antipeptic ulcer activity of the leaf extract of Plantago lanceolata L. in rodents. ( Asad, M; Asres, K; Engidawork, E; Melese, E, 2011) |
| " The acetic acid-induced gastric ulcer model and Western Blot assay (COX-2 and EGF) were also used to evaluate the OEH healing capacity." | 3.77 | Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae). ( de Almeida, AC; de-Faria, FM; Dunder, RJ; Hiruma-Lima, CA; Luiz-Ferreira, A; Manzo, LP; Pellizzon, CH; Rehen, CS; Rozza, AL; Salvador, MJ; Socca, EA; Souza-Brito, AR; Takayama, C; Valim-Araújo, Dde A, 2011) |
| " Subsequently, its protective effect in indomethacin and iodoacetamide induced colitis in rats (45, 90, 180, 270 mg/kg) and acetic acid induced colitis in mice (65, 130, 250, 500 mg/kg) was assessed." | 3.77 | Protective effect of aqueous extract of Bombax malabaricum DC on experimental models of inflammatory bowel disease in rats and mice. ( Jagtap, AG; Niphadkar, PV; Phadke, AS, 2011) |
| " At 200 mg/kg dose, the inhibition ratio of the extract on carrageenan-induced rat hind paw oedema, dextran-induced rat paw oedema, cotton pellet granuloma in rats, carrageenan-induced peritonitis and acetic acid-induced vascular permeability were 59." | 3.77 | Anti-inflammatory and anti-nociceptive activities of Sipunculus nudus L. extract. ( Cai, QX; Dai, ZR; Zhang, CX, 2011) |
| " Treatment of male ICR mice with ETL significantly inhibited the numbers of acetic acid-induced writhing response and the formalin-induced pain in the late phase." | 3.77 | Antioxidant, analgesic, and anti-inflammatory activities of the ethanolic extracts of Taxillus liquidambaricola. ( Chi, CS; Deng, JS; Huang, GJ; Huang, SS; Lin, TH; Shie, PH, 2011) |
| "The antinociceptive effect of MCO was evaluated using several experimental pain models, including thermal nociception methods, such as the tail immersion and the hotplate tests, as well as chemical nociception induced by intraperitoneal acetic acid and subplantar formalin administration in mice." | 3.77 | Antinociceptive and hypnotic properties of Celastrus orbiculatus. ( Cha, DS; Jeon, H; Park, HJ, 2011) |
| "MCO demonstrated strong and dose-dependent antinociceptive activity compared to tramadol and indomethacin in various experimental pain models." | 3.77 | Antinociceptive and hypnotic properties of Celastrus orbiculatus. ( Cha, DS; Jeon, H; Park, HJ, 2011) |
| "TF-P was evaluated in mice for analgesic activity using acetic acid-induced abdominal contractions test and for anti-inflammatory activity using xylene-induced ear oedema model." | 3.77 | The analgesic and anti-rheumatic effects of Thladiantha dubia fruit crude polysaccharide fraction in mice and rats. ( Di, L; Lin, X; Liu, Y; Wang, L; Xu, T; Yang, B; Yang, X; Zhao, D; Zhou, X, 2011) |
| " Milnacipran, a serotonin/noradrenalin reuptake inhibitor, has recently been approved in the USA for fibromyalgia, a chronic pathology characterized by diffused/chronic musculoskeletal pain, and a high prevalence of irritable bowel syndrome." | 3.77 | Milnacipran is active in models of irritable bowel syndrome and abdominal visceral pain in rodents. ( Aliaga, M; Ardid, D; Bardin, L; Depoortère, R; Meleine, M; Muller, E; Newman-Tancredi, A, 2011) |
| " Three more models, acetic acid-induced mouse vascular permeation, cotton pellet-induced rat granuloma, and carrageenan-induced rat hind paw edema were also employed to verify the anti-inflammatory effect of the identified fraction." | 3.77 | Anti-inflammatory activities and mechanisms of action of the petroleum ether fraction of Rosa multiflora Thunb. hips. ( Cao, X; Chan, CO; Chen, S; Guo, D; Guo, Y; Mok, DK; Xu, L; Ye, Y; Yu, Z, 2011) |
| "Injection of acetic acid (1% and 3%) induced pain behaviors and bladder overactivity proportional to the concentration." | 3.76 | Behavioral and urological evaluation of a testicular pain model. ( Tanahashi, M; Uchida, W; Yoshioka, K, 2010) |
| "Injection of dilute acetic acid into the testes produces a reproducible testicular pain model involving testicular inflammation and activation of primary afferent C fibers and suggests a neural pathway for interaction between testicular pain and bladder overactivity." | 3.76 | Behavioral and urological evaluation of a testicular pain model. ( Tanahashi, M; Uchida, W; Yoshioka, K, 2010) |
| " For the anti-inflammatory activity, the carrageenan-induced hind paw edema and acetic acid-induced increased capillary permeability models were used, whereas for the antinociceptive activity, the p-benzoquinone-induced writhing and hot plate tests in mice were used." | 3.76 | Assessment of anti-inflammatory and antinociceptive activities of Olea europaea L. ( Akkol, EK; Baykal, T; Süntar, IP, 2010) |
| " This study aims to investigate granisetron, a 5-HT( 3) receptor antagonist, in acetic acid-induced rat colitis and probable involvement of 5-HT(3) receptors." | 3.76 | Granisetron ameliorates acetic acid-induced colitis in rats. ( Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mousavizadeh, K; Rahimian, R; Rasouli, MR, 2010) |
| " The blueberry extract produced a significant decrease in constrictions induced by acetic acid and caused graded inhibition of the second phase of formalin-induced pain." | 3.76 | Preliminary studies on the antinociceptive activity of Vaccinium ashei berry in experimental animal models. ( Barros, DM; de Castro, MR; de Souza, MM; Dickel, OE; Guterres, L; Henriques, AT; Ramirez, MR, 2010) |
| " Antipyretic (Baker's yeast-induced fever test), analgesic (acetic acid-induced writhing, tail immersion assays), anti-inflammatory (carrageenan-induced paw edema) and in vitro antioxidant (DPPH radical, superoxide radical scavenging) activities of evodione and leptonol were tested." | 3.76 | Antipyretic, analgesic, anti-inflammatory and antioxidant activities of two major chromenes from Melicope lunu-ankenda. ( Baby, S; Chandrasekhar, A; Chandrika, SP; Johnson, AJ; Kumar R, A; Rasheed, SA; Subramoniam, A, 2010) |
| " Synthesized compounds shown significant anti-inflammatory activity comparable to that of Diclofenac sodium in the carrageenan-induced rat paw edema test and all of the compounds were found to be equipotent to Diclofenac sodium in the acetic acid induced writhing analgesic model." | 3.76 | Synthesis and pharmacological evaluation of novel 1-(2-(benzoyl-substituted-2-phenyl-1H-indol-5-carbony) hydrazinyloxy) vinyl nitrate derivatives as potent non-ulcerogenic, analgesic and anti-inflammatory agents. ( Bhandari, SV; Bothara, KG; Burange, PJ; Dhoot, NS; Mokale, VJ; Naik, JB; Raut, MK, 2010) |
| " Intra-peritoneal administration of this GM induced a marked and dose-dependent inhibition of acetic acid-induced visceral pain with an ID(50) of 0." | 3.76 | Chemical structure and selected biological properties of a glucomannan from the lichenized fungus Heterodermia obscurata. ( Baggio, CH; Carbonero, ER; Eliasaro, S; Freitas, CS; Gorin, PA; Iacomini, M; Marcon, R; Pereira, MI; Ruthes, AC; Santos, AR; Sassaki, GL, 2010) |
| "001) dose-dependent analgesic effect in the tail flick, hot plate, and tail clip (central) as well as in acetic acid-induced writhing (peripheral) nociceptive tests in mice, suggesting the involvement of both central and peripheral mechanisms in alleviating the pain response." | 3.76 | Analgesic and antipyretic activities of ethanol extract of Stereospermum suaveolens. ( Kumar, CT; Mpharm, TB, 2010) |
| " Here, we assessed whether rats infected with the tapeworm Hymenolepis diminuta were protected from gastric ulceration induced by the serosal application of acetic acid." | 3.75 | Acetic acid induced ulceration in rats is not affected by infection with Hymenolepis diminuta. ( McKay, DM; Wallace, JL, 2009) |
| "The HE was evaluated in acetic acid and glutamate models of pain or by biting behavior following intrathecal (i." | 3.75 | Involvement of glutamate and cytokine pathways on antinociceptive effect of Pfaffia glomerata in mice. ( Baggio, CH; dos Santos, AC; dos Santos, AR; dos Santos, CA; Freitas, CS; Luiz, AP; Marques, MC; Mayer, B; Twardowschy, A, 2009) |
| "Oral administration of HE produced dose-dependent inhibition of acetic acid-induced visceral pain and glutamate-induced pain, with ID(50) of 64." | 3.75 | Involvement of glutamate and cytokine pathways on antinociceptive effect of Pfaffia glomerata in mice. ( Baggio, CH; dos Santos, AC; dos Santos, AR; dos Santos, CA; Freitas, CS; Luiz, AP; Marques, MC; Mayer, B; Twardowschy, A, 2009) |
| "6% of 10 ml) induced pain and the effects were also compared to aspirin, morphine and naloxone while formalin induced pain (0." | 3.75 | Antinociceptive activity of Amaranthus spinosus in experimental animals. ( Amresh, G; Rao, CV; Singh, S; Zeashan, H, 2009) |
| "It has been shown that the ethanol and aqueous extracts significantly increased the hot-plate pain threshold and reduced acetic acid-induced writhing response in mice." | 3.75 | Anti-inflammatory and analgesic effects of ethanol and aqueous extracts of Pterocephalus hookeri (C.B. Clarke) Höeck. ( Du, GH; Fang, WS; Hu, JJ; Lin, JW; Zhang, L, 2009) |
| "Although decursinol, which is one of the coumarins purified from the dried roots of Angelica gigas Nakai, was previously demonstrated to have antinociceptive effects on various mouse pain models such as tail-flick, hot-plate, formalin, writhing, and several cytokine-induced pain tests, the possible involvement of its analgesic effects and non-steroidal anti-inflammatory drugs (NSAIDs) has not been clearly elucidated yet." | 3.75 | The analgesic effect of decursinol. ( Choi, SM; Huh, GH; Kwon, MS; Lee, JK; Park, SH; Seo, YJ; Sim, YB; Suh, HW, 2009) |
| "The present study examined the antinociceptive effects of (O-methyl) N-benzoyl-tyramine (riparin I, ripI) isolated from the unripe fruit of Aniba riparia in chemical and thermal behavioral models of pain, such as acetic acid-induced abdominal writhing, formalin, and hot-plate tests in mice." | 3.75 | Antinociceptive effects of (O-methyl)-N-benzoyl tyramine (riparin I) from Aniba riparia (Nees) Mez (Lauraceae) in mice. ( Amaral, JF; Araújo, FL; Barbosa-Filho, JM; de Sousa, FC; Gutierrez, SJ; Leite, CP; Melo, CT; Moura, BA; Rocha, NF; Vasconcelos, SM; Viana, GS, 2009) |
| "This study compared effects of the mu opioid receptor agonist morphine (an acknowledged analgesic), the dopamine receptor antagonist haloperidol (a non-analgesic sedative), the adenosine receptor antagonist caffeine (a non-analgesic stimulant) and the neurokinin-1 receptor antagonist CJ 11,974-01 (a candidate analgesic) on acetic acid-induced writhing (a traditional pain-stimulated behavior) and acetic acid-induced suppression of locomotor activity (a pain-depressed behavior) in male ICR mice." | 3.75 | Targeting pain-depressed behaviors in preclinical assays of pain and analgesia: drug effects on acetic acid-depressed locomotor activity in ICR mice. ( Adams, C; Bilsky, EJ; Cormier, J; Dunbar, C; Mercer, H; Negus, SS; Stevenson, GW, 2009) |
| " Pretreatment with a single dose of sophocarpine also produced significant dose-dependent anti-inflammatory effects on carrageenan-induced rat hind paw edema (15 and 30 mg/kg), xylene-induced mouse ear edema (20 and 40 mg/kg) and acetic acid-induced mouse vascular permeation (20 and 40 mg/kg)." | 3.75 | Anti-nociceptive and anti-inflammatory activity of sophocarpine. ( Fu, C; Gao, Y; Li, B; Li, C; Li, G; Li, M; Zhu, X, 2009) |
| "Pretreatment with a single dose of sophocarpine (20 and 40 mg/kg) produced dose-dependent anti-nociceptive effects in thermally and chemically induced mouse pain models." | 3.75 | Anti-nociceptive and anti-inflammatory activity of sophocarpine. ( Fu, C; Gao, Y; Li, B; Li, C; Li, G; Li, M; Zhu, X, 2009) |
| " Chronic gastric ulcers were induced in male Wistar rats by the application of 100% acetic acid to the serosal surface of the stomach on 60 sec." | 3.75 | [Influence of honey, royal jelly and propolis on accelerating acetate healing of experimental gastric ulcers in rats]. ( Belostotskiĭ, NI; Dubtsova, EA; Kas'ianenko, VI; Lazebnik, LB, 2009) |
| ") dose-dependently inhibited nociceptive behavior in the acetic acid-induced pain test." | 3.74 | Quercetin: further investigation of its antinociceptive properties and mechanisms of action. ( de Souza, MM; Filho, AW; Filho, VC; Olinger, L, 2008) |
| " Thalidomide is effective in reducing the extent of arthritis as well as reducing the seizure scoring and increasing seizure onset in the adjuvant arthritis group." | 3.74 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| " The glucan was tested for its effects on the acetic acid-induced writhing reaction in mice, a typical model for quantifying inflammatory pain." | 3.74 | Anti-inflammatory and analgesic properties in a rodent model of a (1-->3),(1-->6)-linked beta-glucan isolated from Pleurotus pulmonarius. ( Baggio, CH; Carbonero, ER; Freitas, CS; Gorin, PA; Iacomini, M; Marcon, R; Olsen, LM; Santos, AR; Smiderle, FR, 2008) |
| "In the present study, we compared the effects of alpha-tocopherol and probucol, antioxidants, on the healing of acetic acid-induced gastric ulcers in 8-, 48- and 96-week-old rats." | 3.74 | Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol. ( Ishihara, M; Ito, M; Kojima, R, 2008) |
| " To determine whether sequentially applied stimuli interact, we determined visceromotor responses (VMR) to gastric distension, measured at baseline and 60 min after instillation of saline, glycocholic acid (GCA) or ethanol through a gastrostomy in controls and rats with gastric ulcers." | 3.74 | Luminal stimuli acutely sensitize visceromotor responses to distension of the rat stomach. ( Bielefeldt, K; Gebhart, GF; Lamb, K, 2007) |
| "We investigated the effects of glutamine on markers of oxidative stress, nuclear factor kappaB (NF-kappaB) activation, and pro-inflammatory mediators in a rat model of experimental colitis induced by intracolonic administration of 7% acetic acid." | 3.74 | Glutamine inhibits over-expression of pro-inflammatory genes and down-regulates the nuclear factor kappaB pathway in an experimental model of colitis in the rat. ( Fillmann, H; González-Gallego, J; Kretzmann, NA; Llesuy, S; Marroni, N; San-Miguel, B; Tuñón, MJ, 2007) |
| "These data demonstrated the comparable efficacy of gabapentin with morphine in visceral pain." | 3.74 | Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice. ( Meymandi, MS; Sepehri, G, 2008) |
| " Here, the antinociceptive effects of MOR agonists, the 6beta-glycine derivative of 14-O-methyloxymorphone (HS-731), DAMGO and morphine were evaluated in a mouse model of visceral pain." | 3.74 | DAMGO and 6beta-glycine substituted 14-O-methyloxymorphone but not morphine show peripheral, preemptive antinociception after systemic administration in a mouse visceral pain model and high intrinsic efficacy in the isolated rat vas deferens. ( Al-Khrasani, M; Friedmann, T; Furst, S; Király, K; Riba, P; Schmidhammer, H; Spetea, M, 2007) |
| " After having established the mouse model of analgesia by intraperitoneal or subcutaneous injections of appropriate doses of emulsified enflurane, isoflurane or sevoflurane, we injected different doses of AMPA intrathecally and observed effects on the pain threshold using the hot-plate and acetic acid-induced writhing tests." | 3.74 | Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics. ( Dai, TJ; Hang, LH; Shao, DH; Yang, YH; Zeng, YM, 2007) |
| " In this study, we examined the effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside (THSG), an active component extracted from Polygonum multiflorum Thunb, on acetic acid-induced acute colitis and mitomycin C-induced chronic colitis." | 3.74 | Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice. ( Chen, S; Han, T; Wang, J; Wang, X; Zhao, L, 2008) |
| " Gastric ulcers were induced by serosal application of absolute acetic acid." | 3.74 | Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis. ( Ae, T; Amagase, K; Arai, K; Hattori, Y; Hayashi, I; Hosono, K; Komine, R; Kurihara, H; Kurihara, Y; Majima, M; Mizuguchi, S; Oh-Hashi, Y; Ohno, T; Okabe, S; Saeki, T; Saigenji, K; Suzuki, T, 2008) |
| " indica dry extract (100, 200 and 400 mg kg-1) exhibited dose dependent and significant anti-inflammatory activity in acute (carrageenean and histamine induced hind paw oedema, p < 0." | 3.74 | Anti-inflammatory and anti-nociceptive activities of Fumaria indica whole plant extract in experimental animals. ( Gupta, PK; Rao, CV; Verma, AR; Vijayakumar, M, 2007) |
| " Based on a clinical observation of synergism between nefopam, a centrally acting non-opioid that inhibits monoamines reuptake, and ketoprofen, a non-steroidal anti-inflammatory drug, the objective of this study was to further explore this antinociceptive synergy in four distinct animal models of pain (both drugs were administered subcutaneously)." | 3.74 | Nefopam and ketoprofen synergy in rodent models of antinociception. ( Coppé, MC; Gillardin, JM; Girard, P; Pansart, Y; Verniers, D, 2008) |
| "There is evidence supporting the antinociceptive effects of carbamazepine, oxcarbazepine, gabapentin, and topiramate in various models of neuropathic pain as well as inflammatory somatic pain." | 3.74 | The antinociceptive effects of anticonvulsants in a mouse visceral pain model. ( Boskovic, B; Milovanovic, S; Paranos, S; Prostran, MS; Stepanovic-Petrovic, RM; Tomic, MA; Ugresic, ND; Vuckovic, SM, 2008) |
| "IBS symptoms were produced in male Sprague-Dawley rats by inducing colitis with acetic acid." | 3.73 | Increase in neurokinin-1 receptor-mediated colonic motor response in a rat model of irritable bowel syndrome. ( Kim, HJ; Kim, JY; Kim, TW; La, JH; Sung, TS; Yang, IS, 2005) |
| " In a chronic model, by acetic acid-induced gastric ulcers, COX-2 was expressed at 7 days and was also associated with PGE(2) increase." | 3.73 | COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions. ( Alarcón de la Lastra, C; Bruseghini, L; Manuel Herrerias, J; Motilva, V; Sánchez-Fidalgo, S, 2005) |
| " Two different animal models, the carrageenin-induced edema, in the rat, and acetic acid-induced writhing test in mice, were adopted." | 3.73 | Anti-inflammatory, anti-nociceptive and antioxidant activities of Balanites aegyptiaca (L.) Delile. ( Cervellati, R; Costa, S; Dall' Acqua, S; Govoni, P; Guerra, MC; Innocenti, G; Speroni, E, 2005) |
| " Since compounds with cytoprotective and antioxidant effects can improve healing of gastroduodenal ulcer induced by noxious agents, this work investigated the healing effect of D- 002 on acute and chronic gastric ulcers induced with indomethacin and acetic acid, respectively, in rats." | 3.73 | Therapeutic effect of D-002 (abexol) on gastric ulcer induced experimentally in rats. ( Arruzazabala, L; Carbajal, D; Más, R; Molina, V, 2005) |
| "Experimental colitis induced by acetic acid has been used extensively as a model for intestinal inflammatory disease." | 3.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| "To assess the cytokine expression pattern identified through immunohistochemistry in colonic mucosa after experimental colitis induced by acetic acid and establish the relationship between this pattern and the presence of macroscopic lesions." | 3.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| "Adult male Wistar rats (n = 39) were divided at random into 4 groups: NC45 and NC24 (control without colitis; sacrificed at 45 minutes and 24 hours, respectively); and WC45 and WC24 (with experimental colitis induced by acetic acid; sacrificed at 45 minutes and 24 hours, respectively)." | 3.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| " Experimental colitis induced by acetic acid is a useful model for the development of studies assessing the role of cytokines in the inflammation of mucosa as well as anti-cytokine therapies." | 3.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| "Colitis was induced by intracolonic administration of acetic acid." | 3.73 | Effects of exopolysaccharide-producing probiotic strains on experimental colitis in rats. ( Aslím, B; Atalay, F; Bozkurt, H; Işik, S; Sakaoğullari, Z; Sengül, N; Uçar, G; Yücel, N, 2006) |
| " Gaultherin, 2-[(6-O-beta-D-Xylopyranosyl-beta-D-glucopyranosyl)oxy] benzoic acid methyl ester, a natural salicylate derivative extracted from Gaultheria yunnanensis, has been shown to have analgesic and anti-inflammatory effects and lack gastric ulcerogenic effect compared to aspirin in our primary study." | 3.73 | Gaultherin, a natural salicylate derivative from Gaultheria yunnanensis: towards a better non-steroidal anti-inflammatory drug. ( Ding, Y; Du, GH; He, XL; Zhang, B, 2006) |
| "The effect of MXY to the mice's gastric ulcer induced by hydrochloric acid-ethanol, reserpine, and chronic gastric ulcer induced by acetic acid were observed." | 3.73 | [Study of the effect of exceed critical extracts from Radix Aucklandiae on experimental gastric ulcer model]. ( Han, J; Lin, H; Rong, X; Zhong, Z, 2005) |
| "5% formalin injection into the hind paw, acetic acid administration intraperitoneally or neuropathic pain testing consisting of mechanical allodynia (von Frey filament) and thermal hyperalgesia (Plantar test)." | 3.73 | Antinociceptive effects of tetrodotoxin (TTX) in rodents. ( Beaulieu, P; Guindon, J; Lu, S; Marcil, J; Ngoc, AH; Walczak, JS, 2006) |
| "Systemic injections of TTX diminished pain behaviour in a dose-dependent manner in models of inflammatory, visceral and neuropathic pain without causing adverse events, whereas morphine analgesia was associated with heavy sedation." | 3.73 | Antinociceptive effects of tetrodotoxin (TTX) in rodents. ( Beaulieu, P; Guindon, J; Lu, S; Marcil, J; Ngoc, AH; Walczak, JS, 2006) |
| ", was investigated using a model of acetic acid-induced colitis in mice." | 3.73 | Protective effect of comaruman, a pectin of cinquefoil Comarum palustre L., on acetic acid-induced colitis in mice. ( Markov, PA; Nikitina, IR; Ovodov, YS; Ovodova, RG; Popov, SV, 2006) |
| " We aimed to investigate the antioxidant effect and the histopathologic changes caused by Gingko biloba on acetic acid-induced colitis." | 3.73 | The effects of Gingko biloba extract on acetic acid-induced colitis in rats. ( Aladağ, M; Ara, C; Demirel, U; Firat, S; Harputluoglu, MM; Hilmioğlu, F; Karadağ, N; Karincaoğlu, M; Temel, I; Yücel, N, 2006) |
| "Thus, a preventive effect of pectin from the common cranberry, namely oxycoccusan OP, on acetic acid-induced colitis in mice was detected." | 3.73 | Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice. ( Markov, PA; Nikitina, IR; Ovodov, YS; Petrishev, S; Popov, SV; Smirnov, V, 2006) |
| " Therefore, we assessed whether a series of desferrithiocin analogs, both carboxylic acids and hydroxamates, could (1) either promote or diminish the iron-mediated oxidation of ascorbate, (2) quench a model radical species, 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+), and (3) when applied topically, prevent acetic acid-induced colitis in rats." | 3.72 | Prevention of acetic acid-induced colitis by desferrithiocin analogs in a rat model. ( Bergeron, RJ; Nguyen, JN; Sninsky, CA; Weimar, WR; Wiegand, J, 2003) |
| " Indomethacin abolished the gross mucosal protective effect by 1% AA pretreatment in 8% AA-derived colitis in normal rats while the NS398 had no effect." | 3.72 | Acetic acid-derived prostaglandin-dependent colonic adaptive cytoprotection is preserved in chronic colitis: role of cyclo-oxygenase. ( Asama, T; Chisato, N; Kasai, S; Kono, T; Ohara, K; Yoneda, M, 2003) |
| "The present work was done to investigate the possible effects of thymoquinone on acetic acid-induced colitis in rats." | 3.72 | Thymoquinone protects against experimental colitis in rats. ( Mahgoub, AA, 2003) |
| "We previously discovered that a 4-wk course of indomethacin delivered to rats with acetic acid ulcers resulted in production of "unhealed gastric ulcers" that persisted for up to 12 wks after treatment cessation." | 3.72 | Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats. ( Amagase, K; Okabe, S; Tsukimi, Y; Yokota, M, 2003) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid in male Sprague-Dawley rats." | 3.72 | Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis. ( Kang, JW; Kim, HJ; Kim, TW; La, JH; Sung, TS; Yang, IS, 2003) |
| " Concerning the gastric effects, lavender oil, linalool and linalyl acetate oral administration protected against acute ethanol-induced gastric ulcers but did not prevent indomethacin-induced lesions indicating no interference with arachidonic acid metabolic cascade." | 3.72 | Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil. ( Ballabeni, V; Barocelli, E; Bianchi, A; Bruni, R; Calcina, F; Chiavarini, M; Impicciatore, M, 2004) |
| " lucidum on the healing of gastric ulcers induced by acetic acid in the rat and to elucidate the underlying mechanisms involved." | 3.72 | Ganoderma lucidum polysaccharide fractions accelerate healing of acetic acid-induced ulcers in rats. ( Chan, E; Gao, H; Gao, Y; Lan, J; Tang, W; Zhou, S, 2004) |
| "5, 5 and 10 mg kg (-1)) was investigated and compared with diclofenac sodium (5 mg kg (-1)) using the formalin-, histamine-, and carrageenan-induced paw oedema and cotton pellet granuloma tests." | 3.71 | Anti-inflammatory and antinociceptive properties of dantrolene sodium in rats and mice. ( Büyükokuroğlu, ME, 2002) |
| "Colitis reduces the blood and tissue levels of adenosine deaminase and adenylate deaminase." | 3.71 | Blood purine and energy status in rats with colitis. ( Al-Awadi, FM; Khan, I, 2001) |
| "Acetic acid-induced gastric ulcers were prepared in 8-week-old male Wistar rats." | 3.71 | Expression of a specific mucin type recognized by monoclonal antibodies in the rat gastric mucosa regenerating from acetic acid-induced ulcer. ( Hayashida, H; Hotta, K; Ichikawa, T; Ishihara, K; Kurihara, M; Okayasu, I; Saigenji, K, 2001) |
| "Proteoglycan expression was studied by immunohistochemistry and in situ hybridization in acetic acid-induced gastric ulcers in rat during early phases and during chronic ulceration." | 3.71 | Expression of decorin and biglycan in rat gastric tissue: effects of ulceration and basic fibroblast growth factor. ( Altenburger, M; Domschke, W; Konturek, JW; Kresse, H; Pohle, T; Shahin, M, 2001) |
| "Expression of MIF was examined in a rat gastric ulcer model induced by acetic acid, and the functional role of MIF in acute gastric ulcer was investigated by administration of a neutralizing anti-MIF antibody." | 3.71 | Macrophage migration inhibitory factor is an important mediator in the pathogenesis of gastric inflammation in rats. ( Bucala, R; Chen, YX; Cho, CH; Chun Hui, CW; Chun, B; Fung, PC; Huang, XR; Hui, WM; Lam, SK; Lan, HY; Metz, C; Wong, BC; Wong, Y, 2001) |
| " These acid-induced writhing reactions were significantly attenuated by capsazepine, a VR1 receptor-specific antagonist, but the phenylbenzoquinone-induced one was not, suggesting that the acids but not phenylbenzoquinone activate the VR1 receptor, which is involved in polymodal pain perception." | 3.71 | Involvement of vanilloid receptor VR1 and prostanoids in the acid-induced writhing responses of mice. ( Ikeda, Y; Naraba, H; Oh-ishi, S; Ueno, A, 2001) |
| " The acute gastric ulcer models used were pylorus ligation, indomethacin, ethanol and histamine induced acute gastric ulcers." | 3.71 | Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001) |
| "9), when given in the dose of 10-50 mg/kg, twice daily for 5 days, showed dose-dependent anti-ulcerogenic on various gastric ulcer models induced by ethanol, aspirin, 2 h cold restraint stress and 4 h pylorus ligation." | 3.71 | Prophylactic and curative effects of Bacopa monniera in gastric ulcer models. ( Babu, MD; Goel, RK; Rao, CV; Sairam, K, 2001) |
| "To investigate the possible role of cyclooxygenase-2 (COX-2) inhibitor NS-398 in formation and healing of acetic acid-induced gastric ulcer in rats." | 3.71 | [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001) |
| "Fourty eight male Sprague-Dawley rats weighed 160-180 g were perfused with acetic acid into the stomach to induce gastric ulcer and then divided into two groups." | 3.71 | [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001) |
| "NS-398 inhibits COX-2 activity, thus alleviating inflammatory reaction in acetic acid induced gastric ulcer and averting further damage of tissues." | 3.71 | [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. ( Shen, X, 2001) |
| "We investigated the effect of probucol, a lipid-lowering agent with antioxidant properties, on HCl plus ethanol-induced gastric mucosal injury and on the healing of acetic acid-induced gastric ulcers in rats." | 3.70 | Anti-ulcer effects of antioxidants: effect of probucol. ( Ishihara, M; Ito, M; Suzuki, Y, 1998) |
| "The healing of experimental gastric ulcers induced in rats is consistently delayed upon chronic treatment with indomethacin." | 3.70 | A new ulcer model, "unhealed gastric ulcers", induced by chronic treatment with indomethacin in rats with acetic acid ulcers. ( Amagase, K; Okabe, S, 1999) |
| " Peptides were active against acetic acid-induced peritonitis in the rats." | 3.70 | Antiinflammatory activity of adrenomedullin in the acetic acid peritonitis in rats. ( Amico-Roxas, M; Caruso, A; Clementi, G; Cutuli, VM; Mangano, NG; Prato, A, 1999) |
| " pylori infection in an acetic acid-induced gastric ulcer (AAU) model in Mongolian gerbils." | 3.70 | Distribution of Helicobacter pylori in a Mongolian gerbil gastric ulcer model. ( Akashi, T; Isobe, Y; Kaneda, Y; Kijima, H; Kimura, M; Miyata, H; Yagi, K, 1999) |
| "The effects of cimetidine, omeprazole and atropine sulfate on the healing of acetic acid-induced gastric ulcers in rats with limited food intake time (9:00-10:00 a." | 3.69 | Effect of cimetidine and omeprazole on gastric ulcer healing of rats with limited food intake time. ( Ito, M; Kojima, R; Segami, T; Suzuki, Y; Tsukahara, T, 1994) |
| " In addition, the plant extract delayed the onset of PTZ forelimb clonus, and generalized limbic seizures induced by kainic acid." | 3.69 | Effects of an ethanolic extract of Desmodium adscendens on central nervous system in rodents. ( Baldy-Moulinier, M; N'gouemo, P; Nguemby-Bina, C, 1996) |
| "An animal model of bilirubinemia was used to determine whether bilirubin present in pigmented teeth can be extracted and qualitatively analysed." | 3.69 | Experimental bilirubin pigmentation of rat dentine and its detection by a qualitative analytical method. ( Arisue, M; Hosokawa, M; Kurosawa, T; Oda, H; Shibata, T; Takeichi, N; Tohma, M; Watanabe, K, 1996) |
| "Amplified chemiluminescence was used to measure reactive oxygen species production by colonic biopsy specimens from rats with acetic acid induced colitis and to assess the in vitro effect of conventional antioxidants, standard therapies and proposed novel therapies for inflammatory bowel disease." | 3.69 | Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis. ( Blades, S; Blake, DR; Chander, CL; Claxson, AW; Coumbe, A; Millar, AD; Morris, CJ; Panetta, J; Rampton, DS, 1996) |
| "The model was validated by demonstrating that the profile of effects on chemiluminescence of acetic acid induced colitis biopsy specimens given by conventional antioxidants (sodium azide, catalase, copper-zinc superoxide dismutase, dimethyl sulphoxide, N-acetylcysteine and ascorbate) and standard therapies (5-aminosalicylate and hydrocortisone) resembled that previously reported using biopsy specimens from ulcerative colitis." | 3.69 | Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis. ( Blades, S; Blake, DR; Chander, CL; Claxson, AW; Coumbe, A; Millar, AD; Morris, CJ; Panetta, J; Rampton, DS, 1996) |
| "The similarity of the chemiluminescence responses of colonic biopsy specimens from acetic acid induced colitis and ulcerative colitis to a range of conventional antioxidants and standard treatments suggests that this model is a useful method for testing the antioxidant potential of new therapies for inflammatory bowel disease." | 3.69 | Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis. ( Blades, S; Blake, DR; Chander, CL; Claxson, AW; Coumbe, A; Millar, AD; Morris, CJ; Panetta, J; Rampton, DS, 1996) |
| "In our study we have tried to compare the prophylactic effects of superoxide dismutase (SOD), SOD+catalase (CAT), desferrioxamine, verapamil and disulfiram, which are all free oxygen radical (FOR) scavengers, in an animal model of experimental acetic acid colitis." | 3.69 | The prophylactic effects of superoxide dismutase, catalase, desferrioxamine, verapamil and disulfiram in experimental colitis. ( Cokneşelí, B; Köksoy, FN; Köse, H; Soybír, GR; Yalçin, O, 1997) |
| "The authors investigated the anti-inflammatory actions of ketoprofen using a battery of tests: in the rat paw oedema test induced by five different inciters, in the capillary permeability test, and in measuring the interleukin-8 (IL-8) production and superoxide dismutase (SOD) activity." | 3.69 | The anti-inflammatory effects of ketoprofen in animal experiments. ( Honda, Y; Koikei, Y; Mineshita, S; Nomura, Y; Shiba, K; Toyoshima, A; Wang, LM; Wang, XX; Yamamoto, T; Yang, L, 1997) |
| "We found indomethacin aggravates healed gastric ulcers (ulcer relapse) in rats." | 3.69 | Prevention of gastric ulcer relapse induced by indomethacin in rats by a mutein of basic fibroblast growth factor. ( Asano, S; Inada, I; Maeda, R; Murakami, I; Sato, F; Satoh, H; Shino, A, 1997) |
| " Therefore, the aim of this study was to examine the role of collagenase and gelatinases A and B in the development and healing of acetic acid-induced gastric ulcer in rats." | 3.69 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
| "Gastric ulcer was induced by injecting 20 microliters glacial acetic acid into gastric wall of rat stomachs." | 3.69 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
| "Immunohistological staining was done using the antibodies for the proliferating cell nuclear antigen prolyl 4-hydroxylase and alpha-smooth muscle actin in acetic acid induced gastric ulcers in rats." | 3.69 | Kinetics of fibroblasts in ulcer healing in rats: interference with indomethacin. ( Arisawa, T; Asai, J; Goto, H; Hase, S; Hayakawa, T; Hirose, Y; Niwa, Y; Tsukamoto, Y, 1997) |
| "The therapeutic efficacy of the leukocyte recruitment inhibitor, NPC 15669 (N-[9H-(2,7-dimethylfluoren-9-yl-methoxy)carbonyl]-L-leucine), was evaluated through the time course of acetic acid colitis in rats." | 3.68 | The leukocyte recruitment inhibitor, NPC 15669 accelerates healing in acetic acid-induced colitis. ( Lowe, VC; Noronha-Blob, L, 1993) |
| " Administration of bFGF (3-300 micrograms/kg/day) by an intragastric or an intraperitoneal route or sucralfate (400 mg/kg/day) orally to rats with acetic acid induced gastric ulcers, enhanced the healing rate of these ulcers during seven day treatment in a dose dependent manner." | 3.68 | Fibroblast growth factor in gastroprotection and ulcer healing: interaction with sucralfate. ( Bielanski, W; Brzozowski, T; Konturek, SJ; Majka, J; Otto, W; Stachura, J; Szlachcic, A, 1993) |
| "The extent of the small intestinal injury following experimental acetic acid induction of colitis in rats was examined." | 3.68 | Acetic acid-induced colitis results in bystander ileal injury. ( Cui, N; Empey, LR; Fedorak, RN, 1993) |
| "Two models of colitis produced in rats that have received significant attention over the past few years are the acetic acid and trinitrobenzene sulfonic acid (TNBS) models." | 3.68 | A comparative analysis of two models of colitis in rats. ( Grisham, MB; Marshall, S; Specian, RD; Yamada, Y, 1992) |
| "The mucosal protective prostaglandin analogs misoprostol, enisoprost, and SC-46275 (the 17E-18-cyclopentenyl analog of enisoprost) were tested in mouse and rat colitis induced by the intrarectal instillation of dilute acetic acid." | 3.68 | Mucosal protective activity of prostaglandin analogs in rodent colonic inflammation. ( Anglin, CP; Collins, PW; Fretland, DJ; Gasiecki, AF; Levin, S; Walsh, RE; Widomski, DL, 1992) |
| " We measured PLA2 activity in the peritoneal leukocytes and eicosanoid content in the peritoneal cavity of rats with experimental colitis induced by dinitrochlorobenzene, immune complex-mediated colitis, and acetic acid-induced colitis." | 3.68 | Increased phospholipase A2 activity in peritoneal leukocytes in rat experimental colitis. ( Biondi, RJ; Murthy, SN, 1992) |
| "The effects of ketotifen, a 'mast cell stabiliser,' on two models of experimental colitis were examined." | 3.68 | Ketotifen effectively prevents mucosal damage in experimental colitis. ( Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D, 1992) |
| "To clarify the mechanism of gastric ulcer recurrence, we studied acetic acid-induced gastric ulcers." | 3.68 | Evaluation of acetic acid-induced gastric ulcers in rats by scanning acoustic microscopy. ( Goto, H; Hase, S; Mizutani, K; Niwa, Y; Ohashi, S; Tsukamoto, Y, 1991) |
| " Myeloperoxidase activity was assayed in two animal models of inflammation: acetic acid-induced colitis in rats and Clostridium difficile enterotoxin-induced enteritis in hamsters." | 3.67 | Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. ( Krawisz, JE; Sharon, P; Stenson, WF, 1984) |
| "To obtain a more precise pathophysiological evaluation of the role of ammonia in acute hepatic encephalopathy, we compared the plasma ammonia concentrations and electroencephalographic recordings (EEGs) of rabbits with surgically induced acute hepatic failure (AHF, n = 10) and normal rabbits administered an infusion of ammonium acetate (NH4-Ac, n = 7) over a 10-hr period." | 3.67 | Continuous intravenous ammonia infusion as a model for the study of hepatic encephalopathy in rabbits. ( de Vlieger, M; Fick, TE; Schalm, SW, 1989) |
| " To more fully evaluate the role of arachidonic acid metabolites in the mediation of intestinal inflammation, we studied arachidonate metabolism in an animal model: acetic acid colitis in the rat." | 3.67 | Metabolism of arachidonic acid in acetic acid colitis in rats. Similarity to human inflammatory bowel disease. ( Sharon, P; Stenson, WF, 1985) |
| "pharnaceoides crude extract in the treatment of ulcerative colitis and might be a promising remedy to manage inflammatory disorders." | 1.72 | Gisekia pharnaceoides Restores Colonic Mucosal Homeostasis by Regulating Antioxidant Enzyme System and Cytokines Signaling in Ulcerative Colitis Mice Model. ( Arshad, HM; Aslam, N; Awan, AM; Jabeen, Q; Javaid, F; Majeed, W, 2022) |
| "pharnaceoides in acetic acid-induced ulcerative colitis in mice and to discover the mechanism for anti-inflammatory action." | 1.72 | Gisekia pharnaceoides Restores Colonic Mucosal Homeostasis by Regulating Antioxidant Enzyme System and Cytokines Signaling in Ulcerative Colitis Mice Model. ( Arshad, HM; Aslam, N; Awan, AM; Jabeen, Q; Javaid, F; Majeed, W, 2022) |
| "In acetic acid-induced ulcerative colitis model, Gp." | 1.72 | Gisekia pharnaceoides Restores Colonic Mucosal Homeostasis by Regulating Antioxidant Enzyme System and Cytokines Signaling in Ulcerative Colitis Mice Model. ( Arshad, HM; Aslam, N; Awan, AM; Jabeen, Q; Javaid, F; Majeed, W, 2022) |
| "Ulcerative colitis is a chronic inflammatory disease, profoundly affecting the patient's quality of life and is associated with various complications." | 1.72 | Linagliptin ameliorates acetic acid-induced colitis via modulating AMPK/SIRT1/PGC-1α and JAK2/STAT3 signaling pathway in rats. ( El-Bahy, AAZ; El-Ghannam, MS; El-Yamany, MF; Nassar, NN; Saad, MA, 2022) |
| "Extensive evidence suggests that gut microbiota may interact with the kidneys and play central roles in the pathogenesis of disease." | 1.72 | Gut-Kidney Impairment Process of Adenine Combined with ( Deng, N; Li, X; Peng, M; Peng, X; Qiao, B; Tan, Z; Yu, R, 2022) |
| "Acetic acid (AA) was used for UC induction, and sulfasalazine (SLZ) was used as a positive control." | 1.62 | Protective effect of mirtazapine against acetic acid-induced ulcerative colitis in rats: Role of NLRP3 inflammasome pathway. ( Abdel-Gaber, SA; Gad, AA; Hafez, HM; Ibrahim, MA; Mohammed Naguib Abdel Hafez, S; Yehia Abdelzaher, W, 2021) |
| "Mirtazapine (MRT) is a well-known antidepressant that was proven to have anti-inflammatory activity; however, to date, its role has not been investigated in UC." | 1.62 | Protective effect of mirtazapine against acetic acid-induced ulcerative colitis in rats: Role of NLRP3 inflammasome pathway. ( Abdel-Gaber, SA; Gad, AA; Hafez, HM; Ibrahim, MA; Mohammed Naguib Abdel Hafez, S; Yehia Abdelzaher, W, 2021) |
| "The effects of GPR120 agonist III on steatohepatitis were evaluated in mice fed with HFHC diet and MCD diet." | 1.62 | G-Protein-Coupled Receptors 120 Agonist III Improves Hepatic Inflammation and ER Stress in Steatohepatitis. ( Chen, X; Liu, C; Ruan, L, 2021) |
| "Chronic pancreatitis affects over 250,000 people in the US and millions worldwide." | 1.62 | Chemical pancreatectomy treats chronic pancreatitis while preserving endocrine function in preclinical models. ( Fusco, J; Gittes, GK; Guo, P; Kalsi, R; Mohamed, N; Prasadan, K; Saleh, M; Saloman, JL; Sehrawat, A; Sharma, K; Wang, Y; Zhang, T, 2021) |
| "Sulfasalazine and JLC were administrated orally and initialized 6 h after TNBS enema, once a day for seven consecutive days." | 1.62 | Jiaolong capsule protects SD rats against 2,4,6-trinitrobenzene sulfonic acid induced colitis. ( Chen, G; Diao, F; Dong, M; Li, Y; Lin, W; Liu, T; Liu, Y; Mei, Q; Ruan, Y; Sun, Y; Tang, T; Zhou, H, 2021) |
| "The acetylcholinesterase inhibitor (ACHEI); neostigmine, is known clinically for its analgesic effect in the perioperative phases proving high efficacy; besides possessing anti-inflammatory properties controlling immune cells and cytokine level." | 1.62 | The effective interplay of (non-) selective NSAIDs with neostigmine in animal models of analgesia and inflammation. ( Abdel-Bary, A; El-Tahan, RA; Gowayed, MA, 2021) |
| "domestica on ulcerative colitis induced by acetic acid in rats." | 1.56 | Effect of Sorbus domestica and its active constituents in an experimental model of colitis rats induced by acetic acid. ( Gürağaç Dereli, FT; Khan, H; Küpeli Akkol, E; Sobarzo-Sánchez, E; Taştan, H, 2020) |
| "Colitis was induced by intra-rectal instillation of 1 ml acetic acid (4%)." | 1.56 | Biochemical and histopathological evidence for the beneficial effects of modafinil on the rat model of inflammatory bowel disease: involvement of nitric oxide pathway. ( Dehpour, AR; Dejban, P; Rahimi, N; Takzare, N, 2020) |
| "Pretreatment with diminazene aceturate, a small molecule with ability to inhibit acid detection through blockade of the acid-sensing ion channel (ASIC) at the doses provided, did not prevent acid-induced pathologic mucus or transport defects but did mitigate airway obstruction." | 1.56 | Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways. ( Atanasova, KR; Bravo, L; Collins, EN; Dadural, JS; Eken, E; Guevara, MV; Kuan, SP; Liao, YSJ; Reznikov, LR; Schurmann, V; Sponchiado, M; Vogt, K, 2020) |
| "Morphine was administered intramuscularly immediately prior to algogen administration." | 1.51 | Nociceptive-like behavior and analgesia in silver catfish (Rhamdia quelen). ( Baldisserotto, B; Barbosa, LB; Bianchini, AE; Ferrari, FT; Heinzmann, BM; Rodrigues, P, 2019) |
| "The poncirin (30 mg/kg) treatment considerably inhibited the mechanical hyperalgesia and allodynia as well as thermal hyperalgesia and cold allodynia." | 1.51 | Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice. ( Afridi, R; Khalid, S; Khan, AU; Khan, S; Kim, YS; Rasheed, H; Shal, B; Shehzad, O; Ullah, MZ, 2019) |
| "Colitis was induced in rats by acetic acid and the rats were divided into four groups where one group served as experimental control and the other groups were treated with two doses of methanol extract of dried latex of C." | 1.51 | Protection afforded by methanol extract of Calotropis procera latex in experimental model of colitis is mediated through inhibition of oxidative stress and pro-inflammatory signaling. ( Das, P; Kumar, VL; Pandey, A; Verma, S, 2019) |
| "Although the magnitude of the hyperalgesia is dependent on the intensity of the conditioning stimulus, we find that the direction of effect is dependent on the effective test stimulus intensity, with lower-intensity stimuli leading to hyperalgesia and higher-intensity stimuli leading to hypoalgesia." | 1.51 | Conditioned pain modulation in rodents can feature hyperalgesia or hypoalgesia depending on test stimulus intensity. ( Austin, JS; Coderre, TJ; Diamond, L; George, N; Macintyre, LC; Martin, LJ; Meluban, L; Mogil, JS; Sotocinal, SG; Tansley, SN, 2019) |
| "The current investigation is focused on solid self-microemulsifying drug-delivery systems (S-SMEDDS) of mefenamic acid (MFA) for improving pharmacodynamic activity." | 1.51 | Mefenamic acid-loaded solid SMEDDS: an innovative aspect for dose reduction and improved pharmacodynamic profile. ( Bedi, N; Kumar, M; Singh, D, 2019) |
| " The optimized liquid SMEDD formulation was spray dried to solid dosage form and observed with enhanced amorphization or molecular dispersion of MFA in S-SMEDDS, as evident from x-ray diffractometry and differential scanning calorimetry studies." | 1.51 | Mefenamic acid-loaded solid SMEDDS: an innovative aspect for dose reduction and improved pharmacodynamic profile. ( Bedi, N; Kumar, M; Singh, D, 2019) |
| "Chronic neuropathic pain is a burden to millions of patients every day." | 1.51 | Neuropathic insult increases the responsiveness to acetic acid in mice. ( Bagdas, D; Damaj, MI; Gurdap, CO; Markwalter, PS; Neddenriep, B, 2019) |
| "Neuropathic pain was induced by chronic constriction injury (CCI) of the sciatic nerve of C57BL/6J male mice and examined in assays of acetic acid (AA)-induced stretching or conditioned place aversion to assess nociceptive and aversive behaviors." | 1.51 | Neuropathic insult increases the responsiveness to acetic acid in mice. ( Bagdas, D; Damaj, MI; Gurdap, CO; Markwalter, PS; Neddenriep, B, 2019) |
| "miliacea in the treatment of fever with possible anti-nociceptive effects." | 1.51 | Antipyretic and anti-nociceptive effects of methanol extract of leaves of Fimbristylis miliacea in mice model. ( Akter, A; Barek, MA; Basher, MA; Liya, IJ; Roy, R; Sultana, S; Ud Daula, AFMS, 2019) |
| "Protocatechuic acid is an antioxidant which is shown to have analgesic activity in limited studies." | 1.51 | Cannabinoid system involves in the analgesic effect of protocatechuic acid. ( Arslan, R; Bektas, N; Dikmen, DY; Okcay, Y, 2019) |
| "In the cedar pollinosis model of mice, a significant reduction was observed in nose scratching of both groups administered with the bacterial cells (30, 150 mg/kg)." | 1.51 | Pollen Allergy Suppression Effect by the Oral Administration of Acetic Acid Bacteria ( ( Amano, S; Inagawa, H; Kochi, C; Nishizawa, T; Soma, GI, 2019) |
| " Both aqueous and alcoholic extracts were found safe at dose of 5000mg/kg." | 1.48 | Acute toxicity study and anti-nociceptive activity of Bauhinia acuminata Linn. leaf extracts in experimental animal models. ( Kulkarni, YA; Londhe, VY; Padgaonkar, AV; Suryavanshi, SV, 2018) |
| "The intermittent REM sleep deprivation stress elicited acceleration of GIT and the increased number of writhes was significantly improved by ST-91 treatment." | 1.48 | Involvement of peripheral alpha2A adrenoceptor in the acceleration of gastrointestinal transit and abdominal visceral pain induced by intermittent deprivation of REM sleep. ( Endo, S; Kozawa, M; Murakami, H; Muto, M; Tadano, T; Tan-No, K; Tsuchiya, M; Yaoita, F, 2018) |
| "treatment with oxyntomodulin during the second, but not the first phase." | 1.48 | Antinociceptive profiles and mechanisms of centrally administered oxyntomodulin in various mouse pain models. ( Hong, JW; Jang, SP; Lee, HJ; Lee, JR; Park, SH; Suh, HW, 2018) |
| "Nonalcoholic fatty liver disease (NAFLD) is associated with low testosterone levels in serum." | 1.48 | Beneficial effect of apple vinegar on reproductive parameters in male rat model of nonalcoholic fatty liver disease. ( Abbasi, M; Aghajany-Nasab, M; Mohammadghasemi, F; Rudkhaneei, K, 2018) |
| "Most drugs used to treat pain and inflammation have potential side effects, which makes it necessary to search for new sources of bioactive molecules." | 1.48 | LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice. ( Alencar Filho, EB; Almeida, JRGDS; Barreiro, EJL; Diniz, TC; Lavor, ÉM; Lima, LM; Lima-Saraiva, SRG; Mendes, RL; Oliveira Júnior, RG; Silva, JC; Silva, MGE; Soares, JMD, 2018) |
| "Pain and inflammation are complex clinical conditions that are present in a wide variety of disorders." | 1.48 | LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice. ( Alencar Filho, EB; Almeida, JRGDS; Barreiro, EJL; Diniz, TC; Lavor, ÉM; Lima, LM; Lima-Saraiva, SRG; Mendes, RL; Oliveira Júnior, RG; Silva, JC; Silva, MGE; Soares, JMD, 2018) |
| "Theophylline treatment also reduced MPO activity and tumor necrosis factor-α (TNF-α), interleukin 1β (IL-1 β) and interleukin 6 (IL-6) concentrations in inflamed colon." | 1.46 | The effect of theophylline on acetic acid induced ulcerative colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "Treatment with theophylline at the doses of 20 and 50mg/kg attenuated acetic acid induced ulcerative colitis as shown by improvement in body weight loss, macroscopic score, ulcer area, hematocrit and histopathological score." | 1.46 | The effect of theophylline on acetic acid induced ulcerative colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "Theophylline has a protective effect in acetic acid-induced ulcerative colitis which might be due to its anti-inflammatory activities." | 1.46 | The effect of theophylline on acetic acid induced ulcerative colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "Ulcerative colitis is a relapsing inflammatory disorder of the colon." | 1.46 | The effect of theophylline on acetic acid induced ulcerative colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "However, the effect of theophylline on ulcerative colitis has not yet been investigated." | 1.46 | The effect of theophylline on acetic acid induced ulcerative colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "Gastric ulcers was induced in the animals of 12 groups with one untreated group being left as the control (Group I - control; given normal saline (NS))." | 1.46 | Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( Akkoc, RF; Aksoy, A; Artas, G; Aydin, S; Dalkilic, S; Gursu, O; Kalayci, M; Kocdor, MA; Kuloglu, T; Ozercan, İH; Sahin, İ; Sarac, M; Ugras, M; Ugur, K; Yardim, M, 2017) |
| "In propranolol-pretreated cats during S1 or S2 stimulation, MTEP (3 mg/kg) significantly (p < 0." | 1.46 | Neurotransmitter Mechanisms Underlying Sacral Neuromodulation of Bladder Overactivity in Cats. ( Bandari, J; Bansal, U; Chang, V; de Groat, WC; Lamm, V; Roppolo, JR; Shen, B; Tai, C; Wang, J; Zhang, Z, 2017) |
| "Visceral pain has a greater emotional component than somatic pain." | 1.46 | Mild Social Stress in Mice Produces Opioid-Mediated Analgesia in Visceral but Not Somatic Pain States. ( Baeyens, JM; Cervero, F; Cobos, EJ; Coderre, TJ; Gonzalez-Cano, R; Lehmann, M; Pitcher, MH; Vincent, K, 2017) |
| "Chronic pain affects the lives of millions yearly, but few new treatments are available." | 1.46 | A novel zebrafish-based model of nociception. ( DeBerry, JJ; Dewberry, LS; Sorge, RE; Taylor, JC; Totsch, SK; Watts, SA; Yessick, LR, 2017) |
| "hastata leaf in the treatment of furuncles may largely derive from anti-inflammatory activities mediated through inhibition of both increase in vascular permeability and leucocyte migration, and stabilization of cell membranes." | 1.43 | Extracts of Leptadenia hastata Leaf, a Famine Food and Traditional Remedy for Furuncles, Suppress Inflammation in Murine Models. ( Akah, PA; Ezea, SC; Ezike, AC; Okoli, CO; Ufere, IK, 2016) |
| "Fifty male Wistar rats were divided into five groups; HFD (80 cal/d) fed rats were orally dosed with fruit vinegars (7 ml/kg) once daily for 28 weeks." | 1.43 | Effect of fruit vinegars on liver damage and oxidative stress in high-fat-fed rats. ( Amiali, M; Bitam, A; Bouazza, A; Bounihi, A; Koceir, EA; Yargui, L, 2016) |
| "Diclofenac sodium was used as a standard drug for comparison." | 1.43 | Studies on anti-inflammatory and analgesic properties of Lactobacillus rhamnosus in experimental animal models. ( Amdekar, S; Singh, V, 2016) |
| "(-)-Linalool is a monoterpene constituent of many essential oils." | 1.43 | Beta-cyclodextrin enhanced gastroprotective effect of (-)-linalool, a monoterpene present in rosewood essential oil, in gastric lesion models. ( da Costa, DS; da Silva, FV; de Barros Fernandes, H; de Cássia Meneses Oliveira, R; de Lira, KL; de Sousa, AA; Lopes, MT; Oliveira, IS; Quintans-Júnior, LJ; Viana, AF, 2016) |
| " EVV produced significant dose-response anti-inflammatory activity against carrageenan-induced paw edema." | 1.43 | Anti-oxidant, anti-inflammatory, analgesic and antipyretic activities of grapevine leaf extract (Vitis vinifera) in mice and identification of its active constituents by LC-MS/MS analyses. ( Aouey, B; Bouaziz, M; Fetoui, H; Samet, AM; Simmonds, MSJ, 2016) |
| "Acetic acid ulcerative colitis (UC) is an experimental condition created due to intra-rectal administration of acetic acid which causes inflammation and ulceration in the lining of colon and rectum." | 1.42 | Mesalazine-probiotics beads for acetic acid experimental colitis: formulation and characterization of a promising new therapeutic strategy for ulcerative colitis. ( Bansal, D; Dubey, N; Ganeshpurkar, A; Pandey, V; Vishwakarma, N, 2015) |
| "Endometritis is a common reproductive disorder in female domestic animals." | 1.42 | Uterine cytokine profile in a rat model of endometritis. ( He, J; Liao, Q; Wang, N; Xiao, Z; Xiong, H; Xu, D; Xue, L; Yang, Q, 2015) |
| "Propranolol treatment also significantly (P = 0." | 1.42 | Propranolol, but not naloxone, enhances spinal reflex bladder activity and reduces pudendal inhibition in cats. ( de Groat, WC; Rogers, MJ; Roppolo, JR; Schwen, Z; Shen, B; Tai, C; Wang, J; Xiao, Z, 2015) |
| "In α-chloralose-anesthetized cats after spinal cord transection at the T9/T10 level, intravesical infusion of 0." | 1.42 | Role of spinal metabotropic glutamate receptor 5 in pudendal inhibition of the nociceptive bladder reflex in cats. ( de Groat, WC; Reese, JN; Rogers, MJ; Roppolo, JR; Schwen, Z; Shen, B; Tai, C; Wang, J; Xiao, Z, 2015) |
| "Kaempferol was shown to attenuate the expansion of inflammatory lesions seen in ethanol (EtOH)/HCl- and aspirin-induced gastritis, LPS/caerulein (CA) triggered pancreatitis, and acetic acid-induced writhing." | 1.42 | Kaempferol, a dietary flavonoid, ameliorates acute inflammatory and nociceptive symptoms in gastritis, pancreatitis, and abdominal pain. ( Baek, KS; Cho, JY; Ha, VT; Kim, E; Kim, HG; Kim, JH; Kim, SH; Lee, MN; Park, JG; Sung, GH; Sung, NY; Yang, S; Yang, WS; Yi, YS, 2015) |
| "Treatment with embelin LNs decreased MPO, LDH and LPO levels, increased reduced GSH levels which indicated better treatment of ulcerative colitis was achieved." | 1.42 | Embelin lipid nanospheres for enhanced treatment of ulcerative colitis - Preparation, characterization and in vivo evaluation. ( Badamaranahalli, SS; Bhagawati, ST; Durg, S; Kopparam, M, 2015) |
| "Embelin LNs were developed using soya bean oil/virgin coconut oil as liquid lipid carrier and soya/egg lecithin as stabilizer by hot homogenization followed by ultrasonication technique." | 1.42 | Embelin lipid nanospheres for enhanced treatment of ulcerative colitis - Preparation, characterization and in vivo evaluation. ( Badamaranahalli, SS; Bhagawati, ST; Durg, S; Kopparam, M, 2015) |
| "Ulcerative colitis is an inflammatory disorder characterized by neutrophils infiltration, oxidative stress, upregulation of pro-inflammatory mediators and cytokines." | 1.42 | Protective effect of cavidine on acetic acid-induced murine colitis via regulating antioxidant, cytokine profile and NF-κB signal transduction pathways. ( He, Z; Li, W; Mu, Q; Niu, X; Wang, X; Wang, Y; Yao, H; Zhang, H, 2015) |
| "Acetic acid bacteria were isolated from various fruits by Nodai kaihen medium." | 1.42 | Oral Administration of Lipopolysaccharide of Acetic Acid Bacteria Protects Pollen Allergy in a Murine Model. ( Amano, S; Inagawa, H; Kohchi, C; Nakata, Y; Ohmori, M; Soma, G, 2015) |
| "We found a significant toxic effect of acetic acid in guinea pigs on eighth-nerve compound action potentials when the pH was 5." | 1.42 | Ototoxicity of acetic acid on the guinea pig cochlea. ( Higuchi, H; Morizono, T; Nakagawa, T; Yamano, T, 2015) |
| "Rotarod and catalepsy tests were used to identify potential side effects, while the functional effect of TRR469 was studied using [(3)H]-d-aspartate release from synaptosomes." | 1.40 | TRR469, a potent A(1) adenosine receptor allosteric modulator, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice. ( Baraldi, PG; Borea, PA; Gessi, S; Merighi, S; Romagnoli, R; Targa, M; Varani, K; Vincenzi, F, 2014) |
| "TRR469 was anti-allodynic in the neuropathic pain model and did not display locomotor or cataleptic side effects." | 1.40 | TRR469, a potent A(1) adenosine receptor allosteric modulator, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice. ( Baraldi, PG; Borea, PA; Gessi, S; Merighi, S; Romagnoli, R; Targa, M; Varani, K; Vincenzi, F, 2014) |
| "Tributyrin (TBU) is a good dietary source of butyrate and has beneficial effects on the maintenance of normal intestinal morphology." | 1.40 | Dietary supplementation with tributyrin alleviates intestinal injury in piglets challenged with intrarectal administration of acetic acid. ( Chen, X; Ding, B; Gong, J; Hou, Y; Liu, Y; Wang, L; Wang, Q; Wu, G; Yi, D; Yin, Y; Zhu, H, 2014) |
| "Acetic acid (AA; 0." | 1.40 | Role of spinal GABAA receptors in pudendal inhibition of nociceptive and nonnociceptive bladder reflexes in cats. ( de Groat, WC; Reese, J; Roppolo, JR; Schwen, Z; Shen, B; Tai, C; Wang, J; Xiao, Z, 2014) |
| "An acetic acid (AA)-induced ulcerative colitis rat model was applied in the study." | 1.40 | The in vivo and in vitro study of polysaccharides from a two-herb formula on ulcerative colitis and potential mechanism of action. ( Jia, W; Lu, H; Ma, C; Qiu, M; Sun, W; Wu, H; Xin, X; Yang, Y; Zhao, A; Zhao, L; Zou, H, 2014) |
| "Acetic acid was given via a rectal route to induce acute colitis in rats." | 1.40 | The protective effect of Echinacea spp. (Echinacea angustifolia and Echinacea purpurea) in a rat colitis model induced by acetic acid. ( Can, M; Dogan, Z; Ergul, B; Filik, L; Gonultaş, MA; Hucumenoglu, S; Sarikaya, M, 2014) |
| "When acacetin was injected, it produced marked effect with maximum activity of 33." | 1.40 | Antipyretic and antinociceptive potential of extract/fractions of Potentilla evestita and its isolated compound, acacetin. ( Khan, H; Khan, R; Pervez, S; Rauf, A; Ullah, B, 2014) |
| "Curcumin treatment was associated with amelioration of macroscopic and microscopic colitis sores, decreased MPO activity, and decreased MDA levels in acetic acid-induced colitis." | 1.39 | Effects of curcumin on apoptosis and oxidoinflammatory regulation in a rat model of acetic acid-induced colitis: the roles of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase. ( Akpolat, M; Cerkezkayabekir, A; Kizilay, G; Omurlu, IK; Sapmaz-Metin, M; Topcu-Tarladacalisir, Y; Uz, YH, 2013) |
| "Twenty-eight gastric hyperalgesia rats and 20 control rats were used." | 1.39 | Desvenlafaxine succinate ameliorates visceral hypersensitivity but delays solid gastric emptying in rats. ( Chen, JD; Dai, F; Lei, Y; Li, S; Song, G, 2013) |
| "The hydrogen treatment was performed once every 2 d and lasted 2 wk." | 1.39 | Protective effects of hydrogen-rich saline on ulcerative colitis rat model. ( He, J; Mei, X; Sun, A; Sun, X; Wang, J; Wang, Q; Xiong, S; Zhang, C; Zhang, J, 2013) |
| "Treatment with hydrogen-rich saline reduced the weight loss and diarrhea and alleviated the colonic mucosal damage in the UC rats." | 1.39 | Protective effects of hydrogen-rich saline on ulcerative colitis rat model. ( He, J; Mei, X; Sun, A; Sun, X; Wang, J; Wang, Q; Xiong, S; Zhang, C; Zhang, J, 2013) |
| "Hydrogen was supplied through intraperitoneal injection of 10 or 20 mL/kg hydrogen-rich saline." | 1.39 | Protective effects of hydrogen-rich saline on ulcerative colitis rat model. ( He, J; Mei, X; Sun, A; Sun, X; Wang, J; Wang, Q; Xiong, S; Zhang, C; Zhang, J, 2013) |
| "Ulcerative colitis is a chronic inflammatory disease and involves multiple etiological factors." | 1.39 | Protective effects of N-acetylcysteine on acetic acid-induced colitis in a porcine model. ( Chen, X; Ding, B; Hou, Y; Liu, Y; Long, M; Wang, L; Wang, Q; Wu, G; Yi, D, 2013) |
| "Tumor necrosis was noted immediately post-injection; by 24 h, ulceration and crusting of overlying skin were noted, which healed into scars by 23 ± 5 days." | 1.39 | Intratumoral acetic acid injection eradicates human prostate cancer tumors in a murine model. ( Bhullar, JS; Chaudhary, S; Decker, M; Mittal, VK; Silberberg, B; Subhas, G; Tilak, J, 2013) |
| "To treat localized prostate cancer without substantial morbidity, an ideal treatment would be an effective local therapy with minimal morbidity." | 1.39 | Intratumoral acetic acid injection eradicates human prostate cancer tumors in a murine model. ( Bhullar, JS; Chaudhary, S; Decker, M; Mittal, VK; Silberberg, B; Subhas, G; Tilak, J, 2013) |
| "PC3 and LNCaP human prostate cancer cell lines were used to grow subcutaneous tumors in SCID mice." | 1.39 | Intratumoral acetic acid injection eradicates human prostate cancer tumors in a murine model. ( Bhullar, JS; Chaudhary, S; Decker, M; Mittal, VK; Silberberg, B; Subhas, G; Tilak, J, 2013) |
| "Treatment with naloxone, L-arginine and glibenclamide reversed the effect of LPEF in glutamate test." | 1.39 | Antinociceptive effect of Lecythis pisonis Camb. (Lecythidaceae) in models of acute pain in mice. ( Almeida, FR; Brandão, MS; Chaves, MH; Ferreira, EL; Lima, DF; Oliveira, JP; Pereira, SS, 2013) |
| "Quercetin (1) is an anti-inflammatory and antioxidant flavonoid." | 1.39 | Quercetin-loaded microcapsules ameliorate experimental colitis in mice by anti-inflammatory and antioxidant mechanisms. ( Baracat, MM; Casagrande, R; Colombo, BB; Fattori, V; Georgetti, SR; Guazelli, CF; Verri, WA; Vicentini, FT, 2013) |
| " Brucine in MTAF was absorbed more completely than it alone at the same dosage of brucine after transdermal administration." | 1.38 | Analgesic and anti-inflammatory activity and pharmacokinetics of alkaloids from seeds of Strychnos nux-vomica after transdermal administration: effect of changes in alkaloid composition. ( Cai, BC; Cai, H; Chen, J; Chen, ZP; Liu, X; Lu, TL; Qu, YG; Wang, X; Xu, F, 2012) |
| "Morphine sulfate was used as reference analgesic agent." | 1.38 | Evaluation of antinociceptive effects of Crassocephalum bauchiense Hutch (Asteraceae) leaf extract in rodents. ( Bum, EN; Dawe, A; De Waard, M; Dimo, T; Dzeufiet, PD; Nguimbou, RM; Sidiki, N; Taïwe, GS; Talla, E, 2012) |
| "Gastric cancer was found in both the anterior and posterior walls of the corpus in all 43 mice." | 1.38 | Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model. ( Cao, H; Chen, D; Johannessen, H; Kodama, Y; Okabe, S; Takahashi, R; Wang, TC; Zhao, CM, 2012) |
| "crassifolius for the treatment of pain and inflammation." | 1.38 | Anti-nociceptive and anti-inflammatory effects of Croton crassifolius ethanol extract. ( Fang, F; Wang, G; Yang, L; Yu, L; Zhao, J, 2012) |
| "Carvacrol was administered orally, at single doses of 50 and 100 mg/kg while indometacin (5 mg/kg), morphine (7." | 1.38 | Antinociceptive activity of carvacrol (5-isopropyl-2-methylphenol) in mice. ( Cavalcante Melo, FH; Citó, Mdo C; de Sousa, DP; de Sousa, FC; de Vasconcelos, SM; Fernandes, ML; Rios, ER; Rocha, NF, 2012) |
| "Melatonin is a powerful antioxidant and a scavenger of hydroxyl radicals." | 1.37 | Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats. ( Aktolga, S; Cetinkaya, A; Dorko, K; Gramignoli, R; Marongiu, F; Tahan, G; Tahan, V, 2011) |
| "Melatonin has also been shown to have anti-inflammatory activities in tissues." | 1.37 | Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats. ( Aktolga, S; Cetinkaya, A; Dorko, K; Gramignoli, R; Marongiu, F; Tahan, G; Tahan, V, 2011) |
| "Colitis was induced by intracolonic administration of acetic acid." | 1.37 | The effect of exopolysaccharide-producing probiotic strains on gut oxidative damage in experimental colitis. ( Aslım, B; Demirbağ, AE; Işık, S; Sengül, N; Uçar, G, 2011) |
| "Embelin treatment significantly decreased clinical activity score, gross lesion score, percent affected area and wet colon weight when compared to acetic acid induced controls." | 1.37 | Protective effect of embelin against acetic acid induced ulcerative colitis in rats. ( Badami, S; Biradar, MI; Mahendran, S; Raj, P; Srivastava, K; Thippeswamy, BS; Veerapur, VP, 2011) |
| " The inhibition of oedema formation increased with increasing dosage from 25 to 100mg/kg." | 1.37 | Analgesic effects and anti-inflammatory properties of the crude methanolic extract of Schwenckia americana Linn (Solanaceae). ( Abdullahi, N; Adebisi, I; Chika, A; Jimoh, AO; Umar, MT, 2011) |
| "Acetic acid was given to 2 groups of animals to induce colitis while the other 2 groups received saline intrarectally." | 1.37 | Vitamin E has a dual effect of anti-inflammatory and antioxidant activities in acetic acid-induced ulcerative colitis in rats. ( Aydin, S; Aytac, E; Aytekin, H; Dogusoy, G; Gunduz, F; Tahan, G; Tahan, V; Uzun, H, 2011) |
| "The role of antidepressants in the treatment of visceral pain has not been extensively examined." | 1.37 | Milnacipran is active in models of irritable bowel syndrome and abdominal visceral pain in rodents. ( Aliaga, M; Ardid, D; Bardin, L; Depoortère, R; Meleine, M; Muller, E; Newman-Tancredi, A, 2011) |
| " The stretching times of mice induced by acetic acid were significantly reduced by EOC at dosage of 0." | 1.37 | [GC-MS analysis and analgesic activity of essential oil from fresh rhizoma of Cyperus rotundus]. ( Chen, Y; Huang, LQ; Liu, JT; Peng, CS; Wang, XY; Zhao, YY, 2011) |
| "Morin was shown to contain an in vivo anti-inflammatory activity using a carrageenan-induced air pouch model in mice." | 1.36 | Evaluation of the antiangiogenic, anti-inflammatory, and antinociceptive activities of morin. ( Jung, HJ; Kim, SJ; Lim, CJ; Park, EH; Song, YS, 2010) |
| "Colitis was rendered by instillation of 1 mL of 4% acetic acid (vol/vol) and after 1 hour, granisetron (2 mg/kg), dexamethasone (1 mg/kg), meta-chlorophenylbiguanide (mCPBG, 5 mg/kg), a 5-HT( 3) receptor agonist, or granisetron + mCPBG was given intraperitoneally." | 1.36 | Granisetron ameliorates acetic acid-induced colitis in rats. ( Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mousavizadeh, K; Rahimian, R; Rasouli, MR, 2010) |
| "Contemporary medications used in the treatment of gastric ulcers involve the use of novel mucosal protective drugs." | 1.36 | Ginger extract and polaprezinc exert gastroprotective actions by anti-oxidant and growth factor modulating effects in rats. ( Ko, JK; Leung, CC, 2010) |
| "Thalidomide was also effective in reducing TNFalpha levels thus contributing to its antiepileptic activity." | 1.35 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| "Inflammation was associated with decreased threshold to PTZ induced seizure." | 1.35 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| "There is higher incidence of seizures among patients with chronic inflammatory disease." | 1.35 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| "Cryptolepine has been shown to inhibit nitric oxide production, and DNA binding of Nuclear Factor-kappa B following inflammatory stimuli in vitro." | 1.35 | Anti-inflammatory properties of cryptolepine. ( Ajayi, AM; Olajide, OA; Wright, CW, 2009) |
| "Myricetin was also not able to increase the sleeping time induced by pentobarbital, which further indicated that the analgesic effect of myricetin was unrelated to sedation." | 1.35 | Analgesic activity of myricetin isolated from Myrica rubra Sieb. et Zucc. leaves. ( Cao, YL; Tong, Y; Wang, SJ; Yang, Y; Zhou, XM, 2009) |
| "Chronic gastric ulcers were induced in male Wistar rats by the application of 100% acetic acid to the serosal surface of the stomach on 60 sec." | 1.35 | [Influence of honey, royal jelly and propolis on accelerating acetate healing of experimental gastric ulcers in rats]. ( Belostotskiĭ, NI; Dubtsova, EA; Kas'ianenko, VI; Lazebnik, LB, 2009) |
| "Visceral pain is one of the most common forms of pain and for which new drugs would be welcome." | 1.35 | Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice. ( Meymandi, MS; Sepehri, G, 2008) |
| "Gastric ulcers were induced by serosal application of absolute acetic acid." | 1.35 | Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis. ( Ae, T; Amagase, K; Arai, K; Hattori, Y; Hayashi, I; Hosono, K; Komine, R; Kurihara, H; Kurihara, Y; Majima, M; Mizuguchi, S; Oh-Hashi, Y; Ohno, T; Okabe, S; Saeki, T; Saigenji, K; Suzuki, T, 2008) |
| "In rat carrageenan-induced tactile allodynia, single administration of nefopam or ketoprofen only partially reduced allodynia." | 1.35 | Nefopam and ketoprofen synergy in rodent models of antinociception. ( Coppé, MC; Gillardin, JM; Girard, P; Pansart, Y; Verniers, D, 2008) |
| "Propionic acid (PPA) is a short chain fatty acid, a metabolic end-product of enteric bacteria in the gut, and a common food preservative." | 1.35 | Intracerebroventricular injection of propionic acid, an enteric bacterial metabolic end-product, impairs social behavior in the rat: implications for an animal model of autism. ( Cain, DP; MacFabe, DF; Ossenkopp, KP; Scratch, S; Shultz, SR; Taylor, R; Whelan, J, 2008) |
| "Ketorolac is a non-steroidal anti-inflammatory drug." | 1.34 | Ketorolac-dextran conjugates: synthesis, in vitro and in vivo evaluation. ( Chaturvedi, SC; Trivedi, P; Vyas, S, 2007) |
| "Ketorolac contents were evaluated by UV-spectrophotometric analysis." | 1.34 | Ketorolac-dextran conjugates: synthesis, in vitro and in vivo evaluation. ( Chaturvedi, SC; Trivedi, P; Vyas, S, 2007) |
| "Mice null for desmin develop dilated cardiomyopathy characterized by extensive cardiomyocyte death, fibrosis, calcification and eventual heart failure." | 1.33 | Alterations in the heart mitochondrial proteome in a desmin null heart failure model. ( Capetanaki, Y; Fountoulakis, M; Maris, A; Mavroidis, M; Rapti, K; Soumaka, E; Tsangaris, G; Weisleder, N, 2005) |
| "Ulcerative colitis is associated with altered contractile activity and transit time of colon." | 1.33 | Proglumide attenuates experimental colitis in rats. ( Al Moutaery, A, 2005) |
| "Acute gastric ulcer was induced with single oral doses of indomethacin (20 mg/kg)." | 1.33 | Therapeutic effect of D-002 (abexol) on gastric ulcer induced experimentally in rats. ( Arruzazabala, L; Carbajal, D; Más, R; Molina, V, 2005) |
| " Administration of either azithromycin or erythromycin at different dosage (10, 20 and 40 mg/kg orally, daily for 5 consecutive days) significantly (P < 0." | 1.33 | Azithromycin and erythromycin ameliorate the extent of colonic damage induced by acetic acid in rats. ( Arafah, M; El-Medany, A; Mahgoub, A; Moursi, M; Mustafa, A, 2005) |
| "Ulcerative colitis is a common inflammatory bowel disease (IBD) of unknown etiology." | 1.33 | Azithromycin and erythromycin ameliorate the extent of colonic damage induced by acetic acid in rats. ( Arafah, M; El-Medany, A; Mahgoub, A; Moursi, M; Mustafa, A, 2005) |
| "Colitis was induced by intracolonic administration of acetic acid." | 1.33 | Effects of exopolysaccharide-producing probiotic strains on experimental colitis in rats. ( Aslím, B; Atalay, F; Bozkurt, H; Işik, S; Sakaoğullari, Z; Sengül, N; Uçar, G; Yücel, N, 2006) |
| "The efficacy of various drugs used to treat ulcerative colitis (UC) was investigated." | 1.33 | Ginkgo biloba attenuates mucosal damage in a rat model of ulcerative colitis. ( El-Medany, A; El-Medany, G; Hagar, HH; Mustafa, A, 2006) |
| "Gastric ulcer is a source of visceral pain." | 1.33 | Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006) |
| "Gastric ulcers were induced by luminal application of 60% acetic acid under surgical conditions." | 1.33 | Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats. ( Bogdanov, A; Filaretova, L; Yarushkina, N, 2006) |
| "Acetic acid (AcOH), which is a short-chain fatty acid, is reported to have some beneficial effects on metabolism." | 1.33 | Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice. ( Kadowaki, T; Oshima, Y; Sakakibara, S; Tsukamoto, Y; Yamauchi, T, 2006) |
| "Morphine was also effective in relieving pain in all three tests but with signs of considerable sedation." | 1.33 | Antinociceptive effects of tetrodotoxin (TTX) in rodents. ( Beaulieu, P; Guindon, J; Lu, S; Marcil, J; Ngoc, AH; Walczak, JS, 2006) |
| "Tetrodotoxin (TTX) is a powerful sodium channel blocker extracted from the puffer fish." | 1.33 | Antinociceptive effects of tetrodotoxin (TTX) in rodents. ( Beaulieu, P; Guindon, J; Lu, S; Marcil, J; Ngoc, AH; Walczak, JS, 2006) |
| "It also diminished mechanical allodynia and thermal hyperalgesia with an ED(50) of 1." | 1.33 | Antinociceptive effects of tetrodotoxin (TTX) in rodents. ( Beaulieu, P; Guindon, J; Lu, S; Marcil, J; Ngoc, AH; Walczak, JS, 2006) |
| "Then the 50 models of ulcerative colitis were randomly assigned into 3 groups: model + placebo group (n = 20, infused intragastrically with normal saline 2 ml/d for 7 days), model + pravastatin group (n = 15, infused intragastrically with pravastatin 1 mg x kg(-1) x d(-1)), and model + salicylazosulfapyridium (SASP) group (n = 15, infused intragastrically with SASP 0." | 1.33 | [Therapeutic effects of pravastatin on colitis induced by acetic acid and relevant mechanism: experiment with rats]. ( Chen, C; Ran, ZH; Xiao, SD, 2006) |
| "Colitis was induced by intracolonic injection of 3% acetic acid." | 1.32 | Thymoquinone protects against experimental colitis in rats. ( Mahgoub, AA, 2003) |
| "Pain was caused by an intraperitoneal injection of 2% acetic acid (0." | 1.32 | [Suppression of visceral pain by action of the low intensity polarized light on acupuncture antinociceptive points]. ( Huliar, SO; Lymans'kyĭ, IuP; Tamarova, ZA, 2003) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid in male Sprague-Dawley rats." | 1.32 | Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis. ( Kang, JW; Kim, HJ; Kim, TW; La, JH; Sung, TS; Yang, IS, 2003) |
| "Acetic acid has been employed as a chemical ablation agent for liver tumors because of its superior diffusion characteristics compared with ethanol and the resulting requirement for smaller volumes and fewer injection sessions." | 1.32 | Percutaneous ablation of VX2 carcinoma-induced liver tumors with use of ethanol versus acetic acid: pilot study in a rabbit model. ( Clark, TW; Furth, EE; Itkin, M; Jacobs, DL; Krasinkas, AM; Shah, SS, 2004) |
| "Colitis was induced by intrarectal administration of acetic acid and followed over a period of seven days." | 1.31 | Blood purine and energy status in rats with colitis. ( Al-Awadi, FM; Khan, I, 2001) |
| "We have developed a new experimental ulcerative colitis model in rats." | 1.31 | [The new experimental ulcerative colitis model in rats induced by subserosal injection of acetic acid]. ( Hamamoto, S; Iwadate, K; Kojima, R; Moriwaki, M; Ohwaki, T, 2001) |
| "The mechanism of tissue damage in ulcerative colitis (UC) is unknown." | 1.31 | Novel antioxidants zolimid and AEOL11201 ameliorate colitis in rats. ( Banan, A; Bocckino, S; Choudhary, S; Day, BJ; Keshavarzian, A; Wade, M; Yong, S, 2001) |
| "Chronic gastric ulcers were induced using acetic acid and duodenal ulcers by cysteamine hydrochloride." | 1.31 | Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001) |
| "The chloroformic fraction was the most interesting, exhibiting a good analgesic and anti-inflammatory activity." | 1.31 | Evaluation of the antinflammatory and analgesic activity of Sideritis canariensis var. pannosa in mice. ( Hernández-Pérez, M; Rabanal, RM, 2002) |
| "In acetic acid-treated rats, this activity increased to 2." | 1.30 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
| "Gastric ulcer was induced by injecting 20 microliters glacial acetic acid into gastric wall of rat stomachs." | 1.30 | Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. ( Baragi, VM; Guglietta, A; Gunja-Smith, Z; Lesch, CA; Qiu, L; Woessner, JF, 1997) |
| "Acute colitis was induced in male FVB mice (about 25 g) by intrarectal administration of 200 microliters of 0." | 1.30 | Induction of plasma hepatocyte growth factor in acute colitis of mice. ( Kawasaki, H; Kojo, H; Matsuno, M; Miura, K; Shiota, G; Umeki, K, 1997) |
| "However, the HE did not affect the hyperalgesia induced by carrageenan or PGE2." | 1.30 | Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae). ( Calixto, JB; Campos, MM; Cechinel Filho, V; Mendes, GL; Santos, AR; Tratsk, KS; Yunes, RA, 1998) |
| "Portal hypertension was induced by staged portal vein ligation." | 1.30 | Delayed healing of acetic-acid-induced gastric ulcer in portal hypertensive rats. ( Baatar, D; Bandoh, T; Kitano, S; Ninomiya, K; Tsuboi, S; Yoshida, T, 1999) |
| "Gastric ulcers were induced by application of acetic acid to the serosal surface of the stomach." | 1.30 | Delayed healing of acetic-acid-induced gastric ulcer in portal hypertensive rats. ( Baatar, D; Bandoh, T; Kitano, S; Ninomiya, K; Tsuboi, S; Yoshida, T, 1999) |
| "Cimetidine was effective at oral doses of over 45." | 1.29 | Healing-promoting action of the zinc-cimetidine complex on acetic acid-induced gastric ulcers in rats. ( Inaguma, K; Ito, M; Segami, T; Suzuki, Y, 1995) |
| "Oral mucositis was induced in male Golden Syrian hamsters with 5-fluorouracil 60 mg/kg intraperitoneal, days 0 and 2." | 1.29 | IL-11, a pleiotropic cytokine: exciting new effects of IL-11 on gastrointestinal mucosal biology. ( Albert, L; Keith, JC; Pfeiffer, CJ; Schaub, RG; Sonis, ST, 1994) |
| "Acetic acid colitis was induced 24 hr before enzyme inhibition began." | 1.29 | Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats. ( Guth, E; Guth, PH; LeDuc, LE; Reedy, T; Su, KC, 1993) |
| "No bilirubin was found in the lower incisors of untreated control rats." | 1.29 | Experimental bilirubin pigmentation of rat dentine and its detection by a qualitative analytical method. ( Arisue, M; Hosokawa, M; Kurosawa, T; Oda, H; Shibata, T; Takeichi, N; Tohma, M; Watanabe, K, 1996) |
| "Acetic acid treatment resulted in increased absorption on day 4, which return to control levels by day 14." | 1.29 | Exudative and absorptive permeability in different phases of an experimental colitis condition. ( McHugh, KJ; Persson, CG; Svensjö, E, 1996) |
| "Colitis was assessed by histology and colonic levels of myeloperoxidase (a neutrophil marker enzyme)." | 1.28 | Mucosal protective activity of prostaglandin analogs in rodent colonic inflammation. ( Anglin, CP; Collins, PW; Fretland, DJ; Gasiecki, AF; Levin, S; Walsh, RE; Widomski, DL, 1992) |
| " Chronic administration of hydrocortisone sodium phosphate resulted in a significant delay of ulcer healing induced by acetic acid." | 1.28 | Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991) |
| "Chronic gastric ulcers were produced in male Wistar rats, weighing 180 g, by the application of 100% acetic acid." | 1.28 | Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991) |
| " Our data suggest that both the route of drug administration and dosing regimen employed affect the antiinflammatory potency and/or efficacy of compounds on colitis induced by acetic acid in the rat." | 1.28 | Antiinflammatory effects of various drugs on acetic acid induced colitis in the rat. ( Bostwick, JS; Decktor, DL; Fitzpatrick, LR; Pendleton, RG; Renzetti, M, 1990) |
| "The efficacy of various drugs used to treat ulcerative colitis, (sulfasalazine, 5-aminosalicylate, hydrocortisone) was investigated in a model of acetic acid-induced colitis in the rat." | 1.28 | Antiinflammatory effects of various drugs on acetic acid induced colitis in the rat. ( Bostwick, JS; Decktor, DL; Fitzpatrick, LR; Pendleton, RG; Renzetti, M, 1990) |
| "Some of the EEG abnormalities of acute hepatic encephalopathy in rabbits are presumably due to hyperammonemia; the encephalopathy observed in AHF at zero time is probably caused by the previously constructed portocaval shunt via an undefined, but possibly also ammonia-related, mechanism." | 1.28 | Continuous intravenous ammonia infusion as a model for the study of hepatic encephalopathy in rabbits. ( de Vlieger, M; Fick, TE; Schalm, SW, 1989) |
| "Acute colitis was induced in 6 Sprague-Dawley rats by acetic acid enema, while 6 control animals received saline enemas." | 1.27 | Identification of experimentally induced colitis by in vitro nuclear magnetic resonance. ( Jacobs, DO; Rolandelli, RH; Rombeau, JL; Saul, SH; Settle, RG; Singer, RL; Wolf, GL, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (1.49) | 18.7374 |
| 1990's | 51 (9.48) | 18.2507 |
| 2000's | 136 (25.28) | 29.6817 |
| 2010's | 283 (52.60) | 24.3611 |
| 2020's | 60 (11.15) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, P | 2 |
| Feng, Z | 1 |
| Sang, X | 1 |
| Chen, W | 1 |
| Zhang, X | 1 |
| Xiao, J | 1 |
| Chen, Y | 3 |
| Chen, Q | 1 |
| Yang, M | 1 |
| Su, J | 1 |
| Hafez, HM | 1 |
| Ibrahim, MA | 1 |
| Yehia Abdelzaher, W | 1 |
| Gad, AA | 1 |
| Mohammed Naguib Abdel Hafez, S | 1 |
| Abdel-Gaber, SA | 1 |
| Fagundes, FL | 1 |
| Pereira, QC | 1 |
| Zarricueta, ML | 1 |
| Dos Santos, RC | 2 |
| Javaid, F | 1 |
| Aslam, N | 1 |
| Arshad, HM | 1 |
| Awan, AM | 1 |
| Majeed, W | 1 |
| Jabeen, Q | 1 |
| El-Ghannam, MS | 1 |
| Saad, MA | 1 |
| Nassar, NN | 1 |
| El-Yamany, MF | 1 |
| El-Bahy, AAZ | 1 |
| Zaghloul, MS | 1 |
| Elshal, M | 1 |
| Abdelmageed, ME | 1 |
| Cao, L | 1 |
| Wu, Y | 2 |
| Li, W | 3 |
| Zhang, Z | 4 |
| Niu, Y | 2 |
| Li, C | 2 |
| Gu, S | 1 |
| Rosa, LV | 2 |
| Costa, FV | 3 |
| Gonçalves, FL | 1 |
| Rosemberg, DB | 3 |
| Li, X | 8 |
| Peng, X | 1 |
| Qiao, B | 1 |
| Peng, M | 1 |
| Deng, N | 1 |
| Yu, R | 1 |
| Tan, Z | 1 |
| Xu, J | 3 |
| Yuan, Z | 3 |
| Li, F | 3 |
| Xu, Z | 4 |
| Chen, Z | 1 |
| Nong, Y | 1 |
| Wang, Q | 4 |
| Feng, L | 1 |
| He, Y | 1 |
| Guo, B | 1 |
| Qin, Y | 1 |
| Zhong, X | 1 |
| Qin, J | 1 |
| Wei, J | 1 |
| Dong, M | 2 |
| Pan, S | 1 |
| Su, Z | 1 |
| Rodrigues, P | 1 |
| Barbosa, LB | 1 |
| Bianchini, AE | 1 |
| Ferrari, FT | 1 |
| Baldisserotto, B | 1 |
| Heinzmann, BM | 1 |
| Osafo, N | 1 |
| Obiri, DD | 1 |
| Danquah, KO | 1 |
| Essel, LB | 1 |
| Antwi, AO | 1 |
| Sun, N | 1 |
| Feng, Y | 1 |
| Zhang, Q | 4 |
| Liu, J | 3 |
| Zhou, H | 2 |
| Zhang, H | 4 |
| Zheng, G | 1 |
| Zhou, J | 3 |
| Yao, G | 1 |
| Afridi, R | 1 |
| Khan, AU | 1 |
| Khalid, S | 1 |
| Shal, B | 1 |
| Rasheed, H | 1 |
| Ullah, MZ | 1 |
| Shehzad, O | 1 |
| Kim, YS | 1 |
| Khan, S | 1 |
| Pacheco, SDG | 1 |
| Gasparin, AT | 1 |
| Jesus, CHA | 1 |
| Sotomaior, BB | 1 |
| Ventura, ACSSB | 1 |
| Redivo, DDB | 1 |
| Cabrini, DA | 1 |
| Gaspari Dias, JF | 1 |
| Miguel, MD | 1 |
| Miguel, OG | 1 |
| da Cunha, JM | 1 |
| Oliveira de Veras, B | 1 |
| Melo de Oliveira, MB | 1 |
| Granja da Silva Oliveira, F | 1 |
| Queiroz Dos Santos, Y | 1 |
| Saturnino de Oliveira, JR | 1 |
| Lúcia de Menezes Lima, V | 1 |
| Guedes da Silva Almeida, JR | 1 |
| Maria do Amaral Ferraz Navarro, D | 1 |
| Ribeiro de Oliveira Farias de Aguiar, JC | 1 |
| Aguiar, JDS | 1 |
| Gorlach-Lira, K | 1 |
| Dias de Assis, CR | 1 |
| Vanusa da Silva, M | 1 |
| Catarina de Souza Lopes, A | 1 |
| Radwan, RR | 1 |
| Abdel Ghaffar, AM | 1 |
| Ali, HE | 1 |
| Iqbal, A | 1 |
| Din, SU | 1 |
| Bakht, J | 1 |
| Khan, IU | 1 |
| Shah, Z | 1 |
| Küpeli Akkol, E | 1 |
| Gürağaç Dereli, FT | 1 |
| Taştan, H | 1 |
| Sobarzo-Sánchez, E | 1 |
| Khan, H | 5 |
| Hosoda, S | 1 |
| Kawazoe, Y | 1 |
| Shiba, T | 1 |
| Numazawa, S | 1 |
| Manabe, A | 1 |
| Dejban, P | 2 |
| Rahimi, N | 1 |
| Takzare, N | 1 |
| Dehpour, AR | 2 |
| Ueno, M | 1 |
| Minagawa, T | 1 |
| Saito, T | 1 |
| Imamura, T | 2 |
| Nagai, T | 1 |
| Ogawa, T | 2 |
| Ishizuka, O | 2 |
| Gandhi, H | 1 |
| Rathore, C | 1 |
| Dua, K | 1 |
| Vihal, S | 1 |
| Tambuwala, MM | 1 |
| Negi, P | 1 |
| Zhao, Y | 1 |
| He, Z | 2 |
| Hao, W | 1 |
| Zhu, H | 2 |
| Liang, N | 1 |
| Zhang, C | 3 |
| Ma, KY | 1 |
| He, WS | 1 |
| Yang, Y | 4 |
| Chen, ZY | 1 |
| Kudryashov, NV | 1 |
| Ivanova, EA | 1 |
| Kalinina, TS | 1 |
| Shimshirt, AA | 1 |
| Kurshin, AA | 1 |
| Zhmurenko, LA | 1 |
| Voronina, TA | 1 |
| Liao, YSJ | 1 |
| Kuan, SP | 1 |
| Guevara, MV | 1 |
| Collins, EN | 1 |
| Atanasova, KR | 1 |
| Dadural, JS | 1 |
| Vogt, K | 1 |
| Schurmann, V | 1 |
| Bravo, L | 1 |
| Eken, E | 1 |
| Sponchiado, M | 1 |
| Reznikov, LR | 1 |
| Sancaktar, ME | 1 |
| Bakırtaş, M | 1 |
| Xia, T | 1 |
| Zhang, B | 2 |
| Li, S | 3 |
| Fang, B | 1 |
| Duan, W | 1 |
| Zhang, J | 5 |
| Song, J | 1 |
| Wang, M | 1 |
| Khaksarian, M | 1 |
| Mahmoudvand, H | 1 |
| Alipour, M | 1 |
| Naizi, M | 1 |
| Hasanvand, KH | 1 |
| Nadri, S | 1 |
| Chen, X | 5 |
| Liu, C | 1 |
| Ruan, L | 1 |
| Lee, D | 1 |
| Ju, MK | 1 |
| Kim, H | 1 |
| Elshazly, SM | 1 |
| Elhassanny, AEM | 1 |
| Mahmoud, NM | 1 |
| Yuan, HL | 2 |
| Zhao, YL | 2 |
| Qin, XJ | 2 |
| Liu, YP | 2 |
| Yu, HF | 1 |
| Zhu, PF | 1 |
| Jin, Q | 1 |
| Yang, XW | 2 |
| Luo, XD | 2 |
| Tanrıkulu, Y | 1 |
| Şen Tanrıkulu, C | 1 |
| Kılınç, F | 1 |
| Can, M | 2 |
| Köktürk, F | 1 |
| Aggarwal, R | 1 |
| Kaushik, P | 1 |
| Kumar, A | 1 |
| Saini, D | 1 |
| Boeing, T | 1 |
| Costa, P | 1 |
| Venzon, L | 1 |
| Meurer, M | 1 |
| Mariano, LNB | 1 |
| França, TCS | 1 |
| Gouveia, L | 1 |
| de Bassi, AC | 1 |
| Steimbach, V | 1 |
| de Souza, P | 1 |
| de Almeida, MO | 1 |
| Arruda, C | 1 |
| de Andrade, SF | 2 |
| Bastos, JK | 3 |
| da Silva, LM | 3 |
| Wu, X | 1 |
| Zheng, Y | 2 |
| Ma, J | 1 |
| Yin, J | 1 |
| Chen, S | 4 |
| Qian, J | 1 |
| Li, G | 2 |
| Jin, X | 1 |
| Ma, C | 2 |
| Cai, W | 1 |
| Jiang, N | 2 |
| Zheng, J | 3 |
| Huang, Y | 2 |
| Li, P | 1 |
| Liu, F | 1 |
| Hou, Q | 1 |
| Bahrami, G | 1 |
| Malekshahi, H | 1 |
| Miraghaee, S | 1 |
| Madani, H | 1 |
| Babaei, A | 1 |
| Ningaraju, S | 1 |
| Munawer, U | 1 |
| Raghavendra, VB | 1 |
| Balaji, KS | 1 |
| Melappa, G | 1 |
| Brindhadevi, K | 1 |
| Pugazhendhi, A | 1 |
| Wang, L | 5 |
| Gu, J | 1 |
| Zong, M | 1 |
| Li, H | 4 |
| Li, D | 1 |
| Mou, X | 1 |
| Liu, P | 1 |
| Liu, Y | 7 |
| Qiu, F | 2 |
| Zhao, F | 1 |
| Alamgeer, - | 1 |
| Nasreen, P | 1 |
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| Asif, H | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Loop Ileostomy Closure as a 23-hour Stay Procedure, a Multi-center Randomized Controlled Trial[NCT03941522] | 168 participants (Anticipated) | Interventional | 2019-06-30 | Not yet recruiting | |||
| The Infant MiND Study: An Examination of Infants' Microbiome, Nutrition, and Development Study.[NCT03229863] | 102 participants (Actual) | Interventional | 2017-04-18 | Active, not recruiting | |||
| Evaluation of the Tolerability and Clinical Effectiveness of Letermovir in Heart Transplantation[NCT04904614] | Phase 4 | 27 participants (Anticipated) | Interventional | 2021-10-01 | Recruiting | ||
| Intravesical Botulinum Toxin A Injection in Treatment of Interstitial Cystitis Refractory to Conventional Treatment - A Prospective, Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial[NCT01969773] | Phase 2 | 60 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| Comparison of the Therapeutic Effects of Different Injection Number of the Same Dose of Botulinum Toxin A on Overactive Bladder Syndrome[NCT01657409] | Phase 2 | 90 participants (Actual) | Interventional | 2012-08-31 | Completed | ||
| Effects of Lavender Aromatherapy and Cold Application on Pain During Drain Removal[NCT04798040] | 121 participants (Actual) | Interventional | 2021-09-01 | Completed | |||
| Elderly Patients With Dementia in the Department of Acute Geriatrics: Pilot Study, Monocentric, Randomized Use of Aromatherapy as a Complementary Treatment to Psychopharmacotherapy in Psychological Disorders and BPSD Behavior[NCT03662360] | 32 participants (Actual) | Interventional | 2018-05-20 | Completed | |||
| A Randomized Prospective Placebo-Controlled Study of the Effects of Lavender Aromatherapy on Preoperative Anxiety in Breast Surgery Patients[NCT01837966] | 93 participants (Actual) | Interventional | 2013-01-31 | Completed | |||
| Use of Hypertonic Versus Isotonic Solutions in Off Pump Coronary Artery Bypass Graft Surgery Targeting the Left Marginal Branch[NCT01463917] | Phase 4 | 20 participants (Anticipated) | Interventional | 2011-09-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The Neuropsychiatric Inventory - Nursing Home Version (NPI-NH) test will characterize the neuropsychiatric and psychopathological symptoms of patients affected by dementia.~Events as delirium, anxiety, depression, etc. will be recorded by the frequency (from 0, absence, to 4, high frequency) and the seriousness (from 0, absence, to 3, high). The total score of the NPI-NH is given by the frequency x (multiply) seriousness (total score for each event has a range from 0 to 12). The patient final score will be given by the sum of the score of the 12 events. For each patient will be given a total score from 0 to 144.~NPI NH score has been collected in both control and aromatherapy groups at T1 and T3, in patients who needed and who did not needed Pro Re Nata." (NCT03662360)
Timeframe: Time 1 (baseline) and Time 3 (day 7)
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| T1 NPI score in patients do not need Pro Re Nata | T3 NPI score in patients needed Pro Re Nata | T3 NPI score in patients do not need Pro Re Nata | |
| GROUP A - Control Group | 21.81 | 32.87 | 20.00 |
| GROUP B - Aromatherapy Group | 25.93 | 16.5 | 7.25 |
NPI-NH assess the psychological distress in physicians, nurses and nursing assistants who managed the patients. It has a score from 0 (no discomfort) to score of 5 (extreme discomfort). The psychological distress is measured for each of the 12 events in the NPI-NH scale, for a total score from 0 to 60. (NCT03662360)
Timeframe: Time 1 (baseline) and Time 3 (day 7)
| Intervention | score on a scale (Mean) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T1 NPI NH physicians in pts with PRN | T1 NPI NH physicians in pts without PRN | T1 NPI NH nurses in pts with PRN | T1 NPI NH nurses in pts without PRN | T1 NPI NH nursing assistants in pts with PRN | T1 NPI NH nursing assistants in pts without PRN | T3 NPI NH physician in pts with PRN | T3 NPI NH physician in pts without PRN | T3 NPI NH nurses in pts with PRN | T3 NPI NH nurses in pts without PRN | T3 NPI NH nursing assistants in pts with PRN | T3 NPI NH nursing assistants in pts without PRN | |
| GROUP A - Control Group | 4.19 | 1.60 | 9.63 | 6.40 | 11.00 | 7.10 | 6.00 | 3.20 | 12.00 | 9.30 | 13.19 | 9.90 |
| GROUP B - Aromatherapy Group | 5.64 | 4.13 | 11.64 | 10.13 | 12.21 | 10.88 | 2.64 | 0.88 | 5.79 | 4.25 | 5.93 | 4.38 |
We hoped to show that lavender aroma therapy reduces preoperative anxiety in patients undergoing breast. The Trait subscale (STAI-TRAID) of the Spielberger State-Trait Anxiety Inventory was administered before and after 10 minutes of aromatherapy treatment pre-surgery. The TRAIT subscale contains 20 questions scored on a Likert scale from 1-4; item scores are summed for a total score ranging from 20 to 80, with higher scores indicating higher anxiety. Change in anxiety was calculated as the score pre-aromatherapy minus the score post-aromatherapy. Higher positive change scores indicate greater reductions in anxiety. (NCT01837966)
Timeframe: 20 minutes before surgery (pre aromatherapy) and 10 minutes before surgery (post aromatherapy)
| Intervention | units on a scale (Mean) |
|---|---|
| Lavender Oil | 0.89 |
| Placebo | .74 |
1 review available for acetic acid and Disease Models, Animal
| Article | Year |
|---|---|
Flavonoids and arachidonic acid metabolism.
Topics: Acetates; Acetic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Carrageenan; Colitis; Disease M | 1988 |
2 trials available for acetic acid and Disease Models, Animal
| Article | Year |
|---|---|
Diosmectite-zinc oxide composite improves intestinal barrier restoration and modulates TGF-β1, ERK1/2, and Akt in piglets after acetic acid challenge.
Topics: Acetic Acid; Animals; Apoptosis; Caspases; Colitis; Dietary Supplements; Disease Models, Animal; Inj | 2015 |
Are probiotics effective in the treatment of fungal colonization of the gastrointestinal tract? Experimental and clinical studies.
Topics: Acetic Acid; Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antif | 2006 |
535 other studies available for acetic acid and Disease Models, Animal
| Article | Year |
|---|---|
Kombucha ameliorates LPS-induced sepsis in a mouse model.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Female; Fermentation; Fermen | 2021 |
Protective effect of mirtazapine against acetic acid-induced ulcerative colitis in rats: Role of NLRP3 inflammasome pathway.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Disease Models, Animal; Humans; Inflammasomes; Int | 2021 |
Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation.
Topics: Acetic Acid; Animals; Anthocyanins; Antioxidants; Biomarkers; Cyclooxygenase 1; Disease Models, Anim | 2021 |
Gisekia pharnaceoides Restores Colonic Mucosal Homeostasis by Regulating Antioxidant Enzyme System and Cytokines Signaling in Ulcerative Colitis Mice Model.
Topics: Acetic Acid; Aizoaceae; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Colon; | 2022 |
Linagliptin ameliorates acetic acid-induced colitis via modulating AMPK/SIRT1/PGC-1α and JAK2/STAT3 signaling pathway in rats.
Topics: Acetic Acid; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Colitis; Cytokines; D | 2022 |
Preventive empagliflozin activity on acute acetic acid-induced ulcerative colitis in rats via modulation of SIRT-1/PI3K/AKT pathway and improving colon barrier.
Topics: Acetic Acid; Animals; Benzhydryl Compounds; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Mod | 2022 |
Cornus officinalis vinegar reduces body weight and attenuates hepatic steatosis in mouse model of nonalcoholic fatty liver disease.
Topics: Acetic Acid; Animals; Cholesterol; Cornus; Diet, High-Fat; Disease Models, Animal; Female; Liver; Mi | 2022 |
Acetic acid-induced nociception modulates sociability in adult zebrafish: Influence on shoaling behavior in heterogeneous groups and social preference.
Topics: Acetic Acid; Animals; Behavior, Animal; Disease Models, Animal; Morphine; Nociception; Social Behavi | 2022 |
Gut-Kidney Impairment Process of Adenine Combined with
Topics: Acetic Acid; Adenine; Animals; Bacteroides; Colitis; Creatinine; Diarrhea; Disease Models, Animal; F | 2022 |
Mitigative effects of dehydrodiisoeugenol on enteritis and co-occurring dysmotility in murine model.
Topics: Acetic Acid; Animals; Diarrhea; Disease Models, Animal; Enteritis; Feces; Mice; Rats | 2022 |
Mitigative effects of dehydrodiisoeugenol on enteritis and co-occurring dysmotility in murine model.
Topics: Acetic Acid; Animals; Diarrhea; Disease Models, Animal; Enteritis; Feces; Mice; Rats | 2022 |
Mitigative effects of dehydrodiisoeugenol on enteritis and co-occurring dysmotility in murine model.
Topics: Acetic Acid; Animals; Diarrhea; Disease Models, Animal; Enteritis; Feces; Mice; Rats | 2022 |
Mitigative effects of dehydrodiisoeugenol on enteritis and co-occurring dysmotility in murine model.
Topics: Acetic Acid; Animals; Diarrhea; Disease Models, Animal; Enteritis; Feces; Mice; Rats | 2022 |
Preventive effect of tilapia skin collagen hydrolysates on ulcerative colitis mice based on metabonomic and 16 S rRNA gene sequencing.
Topics: Acetic Acid; Actinobacteria; Animals; Bacteroidetes; Butyric Acid; Colitis; Colitis, Ulcerative; Col | 2023 |
Nociceptive-like behavior and analgesia in silver catfish (Rhamdia quelen).
Topics: Acetic Acid; Analgesia; Analgesics, Opioid; Animals; Catfishes; Disease Models, Animal; Injections; | 2019 |
Potential effects of xylopic acid on acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antigens, Nuclear; Body Weight; Cell Proliferation; | 2019 |
Analgesic diterpenoids with diverse carbon skeletons from the leaves of Rhododendron auriculatum.
Topics: Acetic Acid; Analgesics; Animals; Carbon; Disease Models, Animal; Diterpenes; Dose-Response Relation | 2019 |
Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chronic Pain; Disease Mo | 2019 |
Antinociceptive and Anti-Inflammatory Effects of Bixin, a Carotenoid Extracted from the Seeds of Bixa orellana.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Bixaceae; Carotenoids; Carrageenan; Dise | 2019 |
Chemical composition and evaluation of the antinociceptive, antioxidant and antimicrobial effects of essential oil from Hymenaea cangaceira (Pinto, Mansano & Azevedo) native to Brazil: A natural medicine.
Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Antioxidants; Brazil; Disease Models, Anima | 2020 |
Gamma radiation preparation of chitosan nanoparticles for controlled delivery of memantine.
Topics: Acetic Acid; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antiparkinson Agents; Brain; Chitosa | 2020 |
Anti-inflammatory, anti-pyretic and analgesic activities of Tamarix dioica.
Topics: Acetic Acid; Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antifungal Agents | 2019 |
Effect of Sorbus domestica and its active constituents in an experimental model of colitis rats induced by acetic acid.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Colitis, Ulcerative; Colon; | 2020 |
Anti-Obesity Effect of Ginkgo Vinegar, a Fermented Product of Ginkgo Seed Coat, in Mice Fed a High-Fat Diet and 3T3-L1 Preadipocyte Cells.
Topics: 3T3 Cells; Acetic Acid; Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; CCAAT-Enhancer-Bindi | 2020 |
Biochemical and histopathological evidence for the beneficial effects of modafinil on the rat model of inflammatory bowel disease: involvement of nitric oxide pathway.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis; Disease Models, Animal; Dose-Response Relat | 2020 |
Therapeutic effects of Choreito, a traditional Japanese (Kampo) medicine, on detrusor overactivity induced by acetic acid in rats.
Topics: Acetic Acid; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Hypoxia-Inducible Facto | 2020 |
Efficacy of resveratrol encapsulated microsponges delivered by pectin based matrix tablets in rats with acetic acid-induced ulcerative colitis.
Topics: Acetic Acid; Animals; Antioxidants; Chemistry, Pharmaceutical; Chitosan; Colitis, Ulcerative; Colon; | 2020 |
Vinegars but not acetic acid are effective in reducing plasma cholesterol in hamsters fed a high-cholesterol diet.
Topics: Acetic Acid; Animals; Cholesterol; Cricetinae; Diet, High-Fat; Disease Models, Animal; Hypercholeste | 2020 |
Antiexudative Effects of Finasteride and a New Pyrazolo[C]Pyridine Derivative GIZh-72 in Acetic Acid-Induced Experimental Peritonitis.
Topics: 5-alpha Reductase Inhibitors; Acetic Acid; Animals; Animals, Outbred Strains; Anti-Inflammatory Agen | 2020 |
Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways.
Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Airway Obstruction; Anima | 2020 |
A potential post-removal pH neutralization strategy to mitigate nasal button battery injuries.
Topics: Acetic Acid; Animals; Cadaver; Disease Models, Animal; Electric Power Supplies; Facial Injuries; For | 2020 |
Vinegar extract ameliorates alcohol-induced liver damage associated with the modulation of gut microbiota in mice.
Topics: Acetic Acid; Animals; Disease Models, Animal; Functional Food; Gastrointestinal Microbiome; Liver Di | 2020 |
Effect of Nectaroscordum koelzi Methanolic Extract on Acute and Chronic Inflammation in Male Mice.
Topics: Acetic Acid; Allium; Animals; Anti-Inflammatory Agents; Capillary Permeability; Disease Models, Anim | 2021 |
G-Protein-Coupled Receptors 120 Agonist III Improves Hepatic Inflammation and ER Stress in Steatohepatitis.
Topics: Acetic Acid; Animals; Apoptosis; Aza Compounds; Disease Models, Animal; Drug Design; Fatty Liver; Li | 2021 |
Commiphora Extract Mixture Ameliorates Monosodium Iodoacetate-Induced Osteoarthritis.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Cartilage, Arti | 2020 |
Cilostazol protects against acetic acid-induced colitis in rats: Possible role for cAMP/SIRT1 pathway.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Cilostazol; Colitis; Colon; Cyclic AMP; Cytoprotecti | 2020 |
Anti-inflammatory and analgesic activities of Neolamarckia cadamba and its bioactive monoterpenoid indole alkaloids.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; Disease Models, | 2020 |
Effects of garlic oil (allium sativum) on acetic acid-induced colitis in rats: Garlic oil and experimental colitis.
Topics: Acetic Acid; Allyl Compounds; Animals; Colitis; Disease Models, Animal; Garlic; Rats; Sulfides | 2020 |
Design, Synthesis and Biological Evaluation of 5-amino-3-aryl-1-(6'-chloropyridazin-3'-yl)pyrazoles and their Derivatives as Analgesic Agents.
Topics: Acetic Acid; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug De | 2020 |
Gastric healing effect of p-coumaric acid isolated from Baccharis dracunculifolia DC on animal model.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Baccharis; Catalase; Cell Line; Cell Proliferation; Cell Su | 2021 |
The Effects of Dietary Glycine on the Acetic Acid-Induced Mouse Model of Colitis.
Topics: Acetic Acid; Animals; Clostridiales; Colitis; Disease Models, Animal; Glycine; Interleukin-10; Inter | 2020 |
Emodin protects against intestinal and lung injury induced by acute intestinal injury by modulating SP-A and TLR4/NF-κB pathway.
Topics: Acetic Acid; Acute Lung Injury; Animals; Colon; Disease Models, Animal; Emodin; Humans; Intestinal M | 2020 |
Ginger relieves intestinal hypersensitivity of diarrhea predominant irritable bowel syndrome by inhibiting proinflammatory reaction.
Topics: Acetic Acid; Animals; China; Diarrhea; Disease Models, Animal; Inflammation; Irritable Bowel Syndrom | 2020 |
Improving Animal Model of Induced Colitis by Acetic Acid in Terms of Fibrosis and Inflammation Incidence in the Colon.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Fibrosis; Incidence; Inflammation; Rat | 2022 |
Chaetomium globosum extract mediated gold nanoparticle synthesis and potent anti-inflammatory activity.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Catechin; Chaetomium; | 2021 |
Anti-inflammatory action of physalin A by blocking the activation of NF-κB signaling pathway.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Disease Models, | 2021 |
Evaluation of anti-inflammatory and analgesic activities of aqueous methanolic extract of Ranunculus muricatus in albino mice.
Topics: Acetic Acid; Albumins; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, A | 2020 |
Short-term Cudrania tricuspidata fruit vinegar administration attenuates obesity in high-fat diet-fed mice by improving fat accumulation and metabolic parameters.
Topics: Acetic Acid; Animals; Biomarkers; Cell Line; Cell Survival; Diet, High-Fat; Disease Models, Animal; | 2020 |
Anti-inflammatory effect of amitriptyline in a rat model of acetic acid-induced colitis: the involvement of the TLR4/NF-kB signaling pathway.
Topics: Acetic Acid; Administration, Oral; Amitriptyline; Animals; Anti-Inflammatory Agents; Colitis; Diseas | 2021 |
Chemical pancreatectomy treats chronic pancreatitis while preserving endocrine function in preclinical models.
Topics: Acetic Acid; Animals; Disease Models, Animal; Macaca fascicularis; Male; Mice; Mice, Transgenic; Pan | 2021 |
Jiaolong capsule protects SD rats against 2,4,6-trinitrobenzene sulfonic acid induced colitis.
Topics: Acetic Acid; Animals; Behavior, Animal; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Dinoprostone; | 2021 |
Pharmacologycal activity of peperina (Minthostachys verticillata) on gastrointestinal tract.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Behavior, Animal; Capsaicin; Castor Oil; Colitis, Ul | 2021 |
Vildagliptin attenuates acetic acid-induced colitis in rats via targeting PI3K/Akt/NFκB, Nrf2 and CREB signaling pathways and the expression of lncRNA IFNG-AS1 and miR-146a.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Apoptosis; Colitis; Cyclic AMP Response Element-Binding | 2021 |
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum.
Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan | 2021 |
The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Baccharis; Brazil; Caspases; Cyclooxygenase 1; Cyclooxygena | 2021 |
Pharmacological investigation of analgesic and antipyretic activities of methanol extract of the whole part of Aeginetia indica.
Topics: Acetic Acid; Analgesics; Animals; Antioxidants; Antipyretics; Behavior, Animal; Disease Models, Anim | 2021 |
The anti-nociceptive effects of ethanol extract of aerial parts of Schkuhria pinnata in mice.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Asteraceae; Behavior, Animal; Disease Models | 2021 |
Synthesis and antimalarial and anticancer evaluation of 7-chlorquinoline-4-thiazoleacetic derivatives containing aryl hydrazide moieties.
Topics: A549 Cells; Acetic Acid; Animals; Antimalarials; Antineoplastic Agents; Apoptosis; Cell Cycle Checkp | 2021 |
Comparison of analgesic activities of aconitine in different mice pain models.
Topics: Acetic Acid; Aconitine; Analgesics; Animals; Aspirin; Disease Models, Animal; Edema; Female; Formald | 2021 |
Regulation of IL-6/STAT-3/Wnt axis by nifuroxazide dampens colon ulcer in acetic acid-induced ulcerative colitis model: Novel mechanistic insight.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Colitis, Ulcerative; Disease Mod | 2021 |
Design, synthesis and molecular modeling studies of novel mesalamine linked coumarin for treatment of inflammatory bowel disease.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Coumarins; Disease Models, Animal; Do | 2021 |
The effective interplay of (non-) selective NSAIDs with neostigmine in animal models of analgesia and inflammation.
Topics: Acetic Acid; Analgesia; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Dic | 2021 |
Central and peripheral pain intervention by Ophiorrhizarugosa leaves: Potential underlying mechanisms and insight into the role of pain modulators.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Central N | 2021 |
Acetic acid treatment causes renal inflammation and chronic kidney disease in mice.
Topics: Acetic Acid; Animals; Creatine; Disease Models, Animal; Gene Expression; Interleukin-1beta; Kidney; | 2021 |
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Topics: Acetic Acid; Animals; Aorta; Atherosclerosis; Benzyl Alcohols; Butyric Acid; Disease Models, Animal; | 2021 |
Eremomastax speciosa (Hochst.) Cufod. counteracts the delaying effect of indomethacin on Helicobacter pylori-associated chronic gastric ulcers healing.
Topics: Acanthaceae; Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Disease Models, Animal; Dose-Res | 2021 |
Comprehensive investigations for a potential natural prophylaxis-A cellular and murine model for apple cider vinegar against hydrogen peroxide and scopolamine induced oxidative stress.
Topics: Acetic Acid; Acetylcholinesterase; Animals; Antioxidants; Disease Models, Animal; Hydrogen Peroxide; | 2022 |
Evaluation of the Cholesterol-Lowering Mechanism of
Topics: Acetic Acid; Animals; Anticholesteremic Agents; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Choles | 2021 |
Inhibition of acetic acid-induced colitis in rats by new Pediococcus acidilactici strains, vitamin producers recovered from human gut microbiota.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Bacterial Agents; Bile Acids and Salts; Colitis; Co | 2021 |
The effect of theophylline on acetic acid induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Disease Models, Animal; | 2017 |
Hydro-ethanolic leaf extract of Ziziphus abyssinica Hochst Ex A. Rich (Rhamnaceae) exhibits anti-nociceptive effects in murine models.
Topics: Acetic Acid; Africa; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; D | 2017 |
Synergistic analgesic, anti-pyretic and anti-inflammatory effects of extra virgin olive oil and ibuprofen in different experimental models of albino mice.
Topics: Acetic Acid; Albinism; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Carrageenan; Din | 2017 |
Phytochemical and biological assessments on Lipidium meyenii (maca) and Epimidium sagittatum (horny goat weed).
Topics: Acetic Acid; Analgesics; Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Dise | 2017 |
Report: Analgesic and anti-inflammatory activity of aqueous-methanolic extract of Aerva javanica.
Topics: Acetic Acid; Amaranthaceae; Analgesics; Animals; Anti-Inflammatory Agents; Chondrus; Disease Models, | 2017 |
Synergism between Naproxen and Rutin in a Mouse Model of Visceral Pain.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Disease Models, Animal; Dose-Response Relati | 2017 |
Proteins from the Rhinella schneideri parotoid gland secretion exhibit anti-nociceptive effect against nociception induced by inflammation.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Bufonidae; Disease Models, Animal; Edema | 2017 |
Supplementation with Lactobacillus paracasei or Pediococcus pentosaceus does not prevent diarrhoea in neonatal pigs infected with Escherichia coli F18.
Topics: Acetic Acid; Animals; Animals, Newborn; Butyric Acid; Colon; Colony Count, Microbial; Diarrhea; Diet | 2017 |
Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Disease Models, Animal; Dose-Response Relationship, Drug; G | 2017 |
A rat model for studying electroacupuncture analgesia on acute visceral hyperalgesia.
Topics: Acetic Acid; Acute Disease; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Elect | 2018 |
Comparison of cannabinoids with known analgesics using a novel high throughput zebrafish larval model of nociception.
Topics: Acetaminophen; Acetic Acid; Analgesics; Animals; Cannabinoid Receptor Agonists; Cannabinoids; Diseas | 2018 |
CGRPα within the Trpv1-Cre population contributes to visceral nociception.
Topics: Acetic Acid; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Disease Models, Animal; Gan | 2018 |
Acute toxicity study and anti-nociceptive activity of Bauhinia acuminata Linn. leaf extracts in experimental animal models.
Topics: Acetic Acid; Analgesics; Animals; Bauhinia; Disease Models, Animal; Male; Mice; Pain; Pain Measureme | 2018 |
Synthesis, antinociceptive activity and structure activity relationship of flavone derivatives.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Flavones; Formaldehyde; | 2017 |
Analgesic activities of crude ethanolic extract and various fractions of Adansonia digitata L. grown at the sindh province of Pakistan.
Topics: Acetic Acid; Adansonia; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response | 2017 |
Evaluation of the effects of a new series of SMTPs in the acetic acid-induced embolic cerebral infarct mouse model.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Cerebral Infarction; Disease Models, A | 2018 |
Synthesis, characterization and antinociceptive activities of Novel 2-(2,4-dichlorophenyl)-4H-chromen-4-one.
Topics: Acetic Acid; Analgesics; Animals; Carbon-13 Magnetic Resonance Spectroscopy; Chromones; Disease Mode | 2017 |
A New Determinant of
Topics: Acetic Acid; Animals; Candida glabrata; Candidiasis; Cell Membrane; Cell Proliferation; Disease Mode | 2017 |
Healing and Antisecretory Effects of Aqueous Extract of
Topics: Acanthaceae; Acetic Acid; Animals; Antioxidants; Disease Models, Animal; Gastric Mucosa; Humans; Ind | 2017 |
Topical action of Buriti oil (Mauritia flexuosa L.) in myositis induced in rats.
Topics: Acetic Acid; Administration, Topical; Animals; Arecaceae; Carotenoids; Disease Models, Animal; Fibro | 2017 |
A Mouse Model for Oral Mucositis Induced by Cancer Chemotherapy.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Disease Models, Animal; Fluor | 2018 |
Pharmacological activities of the organic extracts and fatty acid composition of the petroleum ether extract from Haplophyllum tuberculatum leaves.
Topics: Acetic Acid; Alkanes; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carrageenan; | 2018 |
Involvement of peripheral alpha2A adrenoceptor in the acceleration of gastrointestinal transit and abdominal visceral pain induced by intermittent deprivation of REM sleep.
Topics: Acetic Acid; Acridines; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; | 2018 |
Antinociceptive profiles and mechanisms of centrally administered oxyntomodulin in various mouse pain models.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Cytokines; Disease Models, Animal; Formaldehyde; | 2018 |
Antinociceptive and anti-inflammatory activities of a standardizedextract of bis-iridoids from Pterocephalus hookeri.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Caprifoliaceae; Carrageenan; Dexamethaso | 2018 |
Anti-nociceptive effect of methanol extract of leaves of Senna singueana in mice.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationsh | 2018 |
Antinociceptive effects of the endogenous cannabinoid peptide agonist VD-hemopressin(β) in mice.
Topics: Acetic Acid; Analgesics; Animals; Area Under Curve; Disease Models, Animal; Dose-Response Relationsh | 2018 |
Neuronal glucose metabolism is impaired while astrocytic TCA cycling is unaffected at symptomatic stages in the hSOD1
Topics: Acetic Acid; Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Citric Acid Cycle; Disease Models, | 2019 |
Increased Asics Expression via the Camkii-CREB Pathway in a Novel Mouse Model of Trigeminal Pain.
Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acrylamides; Amiloride; A | 2018 |
Beneficial effect of apple vinegar on reproductive parameters in male rat model of nonalcoholic fatty liver disease.
Topics: Acetic Acid; Animals; Disease Models, Animal; Infertility, Male; Liver; Male; Malus; Non-alcoholic F | 2018 |
Frequency Dependent Tibial Neuromodulation of Bladder Underactivity and Overactivity in Cats.
Topics: Acetic Acid; Animals; Biophysical Phenomena; Biophysics; Cats; Disease Models, Animal; Electric Stim | 2018 |
Metabolic Response in Rabbit Urine to Occurrence and Relief of Unilateral Ureteral Obstruction.
Topics: Acetic Acid; Alanine; Analysis of Variance; Animals; Biomarkers; Citric Acid; Creatinine; Disease Mo | 2018 |
Effects of Gamisoyo-San Decoction, a Traditional Chinese Medicine, on Gastrointestinal Motility.
Topics: Acetic Acid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herba | 2018 |
LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrage | 2018 |
Hepatocyte Growth Factor Facilitates Esophageal Mucosal Repair and Inhibits the Submucosal Fibrosis in a Rat Model of Esophageal Ulcer.
Topics: Acetic Acid; Animals; Cell Proliferation; Disease Models, Animal; Epithelial Cells; Esophageal Disea | 2019 |
Understanding nociception-related phenotypes in adult zebrafish: Behavioral and pharmacological characterization using a new acetic acid model.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Animals, Outbred Strains; Anti-Inflammatory Agents, Non-St | 2019 |
Sex-specific effects of
Topics: Acetic Acid; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Eugenia; Female; Gastric | 2018 |
Oral administration of the selective GPR120/FFA4 agonist compound A is not effective in alleviating tissue inflammation in mouse models of prototypical autoimmune diseases.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheu | 2018 |
Comparative analgesic evaluation of Himalrandia tetrasperma and Wendlandia exserta of family Rubiaceae after induction of pain in mice.
Topics: Acetic Acid; Analgesics; Animals; Aspirin; Behavior, Animal; Disease Models, Animal; Hot Temperature | 2018 |
Analgesic Activity of Acid-Sensing Ion Channel 3 (ASIС3) Inhibitors: Sea Anemones Peptides Ugr9-1 and APETx2 versus Low Molecular Weight Compounds.
Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Analgesics; Animals; Biol | 2018 |
Protection afforded by methanol extract of Calotropis procera latex in experimental model of colitis is mediated through inhibition of oxidative stress and pro-inflammatory signaling.
Topics: Acetic Acid; Animals; Calotropis; Colitis; Disease Models, Animal; Female; Inflammation; Inflammatio | 2019 |
Olmesartan ameliorates chemically-induced ulcerative colitis in rats via modulating NFκB and Nrf-2/HO-1 signaling crosstalk.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Colitis, U | 2019 |
Conditioned pain modulation in rodents can feature hyperalgesia or hypoalgesia depending on test stimulus intensity.
Topics: Acetic Acid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Facial Pain; Formald | 2019 |
Bmi1 marks gastric stem cells located in the isthmus in mice.
Topics: Acetic Acid; Animals; Biomarkers; Cell Differentiation; Cell Lineage; Cell Proliferation; Disease Mo | 2019 |
Laser-capture microdissection of murine lung for differential cellular RNA analysis.
Topics: Acetic Acid; Animals; Asthma; Chloroform; Disease Models, Animal; Ethanol; Female; Gene Expression P | 2019 |
Mefenamic acid-loaded solid SMEDDS: an innovative aspect for dose reduction and improved pharmacodynamic profile.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Avai | 2019 |
The Controlled Release and Anti-Inflammatory Activity of a Tetramethylpyrazine-Loaded Thermosensitive Poloxamer Hydrogel.
Topics: Acetic Acid; Adhesiveness; Administration, Cutaneous; Administration, Intranasal; Administration, Or | 2019 |
Glyoxylate cycle gene ICL1 is essential for the metabolic flexibility and virulence of Candida glabrata.
Topics: Acetic Acid; Animals; Candida glabrata; Candidiasis; Disease Models, Animal; Ethanol; Female; Fungal | 2019 |
Neuropathic insult increases the responsiveness to acetic acid in mice.
Topics: Acetic Acid; Animals; Conditioning, Classical; Disease Models, Animal; Hyperalgesia; Male; Mice; Mic | 2019 |
Protective effect of polysaccharides from Radix Hedysari on gastric ulcers induced by acetic acid in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Cell Movement; Cell | 2019 |
Naloxone prolongs abdominal constriction writhing-like behavior in a zebrafish-based pain model.
Topics: Abdomen; Acetic Acid; Animals; Behavior, Animal; Constriction, Pathologic; Disease Models, Animal; N | 2019 |
Budesonide-Loaded Eudragit S 100 Nanocapsules for the Treatment of Acetic Acid-Induced Colitis in Animal Model.
Topics: Acetic Acid; Animals; Budesonide; Colitis; Disease Models, Animal; Drug Delivery Systems; Drug Liber | 2019 |
Antipyretic and anti-nociceptive effects of methanol extract of leaves of Fimbristylis miliacea in mice model.
Topics: Acetic Acid; Analgesics; Animals; Antipyretics; Cyperaceae; Disease Models, Animal; Female; Fever; F | 2019 |
Cannabinoid system involves in the analgesic effect of protocatechuic acid.
Topics: Acetic Acid; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxyb | 2019 |
Pollen Allergy Suppression Effect by the Oral Administration of Acetic Acid Bacteria (
Topics: Acetic Acid; Administration, Oral; Allergens; Animals; Anti-Allergic Agents; Disease Models, Animal; | 2019 |
Purification and characterization of a novel antinociceptive peptide from venom of Agkistrodon halys Pallas.
Topics: Acetic Acid; Agkistrodon; Amino Acid Sequence; Analgesics; Animals; Behavior, Animal; Chemical Fract | 2013 |
TRP and ASIC channels mediate the antinociceptive effect of citronellyl acetate.
Topics: Acetic Acid; Acid Sensing Ion Channels; Acute Pain; Administration, Oral; Analgesics; Animals; Disea | 2013 |
Systemic synergism between codeine and morphine in three pain models in mice.
Topics: Acetic Acid; Acute Pain; Analgesics, Opioid; Animals; Behavior, Animal; Codeine; Disease Models, Ani | 2013 |
Effects of curcumin on apoptosis and oxidoinflammatory regulation in a rat model of acetic acid-induced colitis: the roles of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Colitis, Ulcerative; Colon; | 2013 |
Effect of hydroalcoholic extract of Hibiscus rosa sinensis Linn. leaves in experimental colitis in rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Glutathione; Hibiscus; Male; Malondial | 2012 |
In vitro binding affinities of a series of flavonoids for μ-opioid receptors. Antinociceptive effect of the synthetic flavonoid 3,3-dibromoflavanone in mice.
Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relation | 2013 |
Arbortristoside-A and 7-O-trans-cinnamoyl-6β-hydroxyloganin isolated from Nyctanthes arbortristis possess anti-ulcerogenic and ulcer-healing properties.
Topics: Acetic Acid; Alcohols; Animals; Anti-Ulcer Agents; Cinnamates; Disease Models, Animal; Female; Irido | 2013 |
Desvenlafaxine succinate ameliorates visceral hypersensitivity but delays solid gastric emptying in rats.
Topics: Acetic Acid; Administration, Oral; Adrenergic Uptake Inhibitors; Animals; Cyclohexanols; Desvenlafax | 2013 |
Protective effects of hydrogen-rich saline on ulcerative colitis rat model.
Topics: Acetic Acid; Animals; Antioxidants; Colitis, Ulcerative; Disease Models, Animal; Hydrogen; Injection | 2013 |
Role of nesfatin-1 in a rat model of visceral hypersensitivity.
Topics: Abdominal Pain; Acetic Acid; Animals; Antibodies; Behavior, Animal; Calcium-Binding Proteins; Colon; | 2013 |
Synthesis and biological evaluation of aminobenzimidazole derivatives with a phenylcyclohexyl acetic acid group as anti-obesity and anti-diabetic agents.
Topics: Acetic Acid; Animals; Anti-Obesity Agents; Benzimidazoles; Cells, Cultured; Cyclization; Diabetes Me | 2013 |
Antinociceptive effect of berberine on visceral hypersensitivity in rats.
Topics: Acetic Acid; Analgesics; Animals; Berberine; Colon; Defecation; Disease Models, Animal; Disease Prog | 2013 |
Autophagy and cathepsin L are involved in the antinociceptive effect of DMBC in a mouse acetic acid-writhing model.
Topics: Acetic Acid; Analgesics; Animals; Autophagy; Benzylidene Compounds; Cathepsin L; Cyclopentanes; Dise | 2013 |
Zinc(II)-curcumin accelerates the healing of acetic acid-induced chronic gastric ulcers in rats by decreasing oxidative stress and downregulation of matrix metalloproteinase-9.
Topics: Acetic Acid; Animals; Curcumin; Disease Models, Animal; Down-Regulation; Gastric Mucosa; Glutathione | 2013 |
The anti-inflammatory and anti-nociceptive activities of Patrinia villosa and its mechanism on the proinflammatory cytokines of rats with pelvic inflammation.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; | 2012 |
Ethanolic extract of Aconiti Brachypodi Radix attenuates nociceptive pain probably via inhibition of voltage-dependent Na⁺ channel.
Topics: Acetic Acid; Aconitum; Analgesics; Animals; Dinoprostone; Disease Models, Animal; Dose-Response Rela | 2012 |
Protective effects of N-acetylcysteine on acetic acid-induced colitis in a porcine model.
Topics: Acetic Acid; Acetylcysteine; Amphiregulin; Animals; Apoptosis; Caspase 3; Claudin-1; Colitis; Coliti | 2013 |
Stability of the acetic acid-induced bladder irritation model in alpha chloralose-anesthetized female cats.
Topics: Acetic Acid; Adrenergic Uptake Inhibitors; Anesthesia; Animals; Blood Pressure; Cats; Chloralose; Di | 2013 |
Anti-inflammatory and analgesic activity of R.A.P. (Radix Angelicae Pubescentis) ethanol extracts.
Topics: Acetic Acid; Analgesics; Angelica; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, A | 2013 |
Analgesic effects of Huwentoxin-IV on animal models of inflammatory and neuropathic pain.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Formaldehyde; Inflammati | 2014 |
Neuromodulation attenuates bladder hyperactivity in a rat cystitis model.
Topics: Acetic Acid; Animals; Cystitis; Disease Models, Animal; Male; Pressure; Rats; Rats, Sprague-Dawley; | 2013 |
Altered gut microbiota and activity in a murine model of autism spectrum disorders.
Topics: Acetic Acid; Animals; Butyric Acid; Child Development Disorders, Pervasive; Disease Models, Animal; | 2014 |
TRR469, a potent A(1) adenosine receptor allosteric modulator, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice.
Topics: Acetic Acid; Allosteric Regulation; Analgesics; Animals; Catalepsy; CHO Cells; Cricetinae; Cricetulu | 2014 |
Antinociceptive effect of certain dimethoxy flavones in mice.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationsh | 2014 |
Mesalazine-probiotics beads for acetic acid experimental colitis: formulation and characterization of a promising new therapeutic strategy for ulcerative colitis.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Colitis, Ulcerative; C | 2015 |
Alpha amylase enzyme inhibitory and anti-inflammatory effect of Lawsonia inermis.
Topics: Acetic Acid; alpha-Amylases; Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; | 2013 |
Dietary supplementation with tributyrin alleviates intestinal injury in piglets challenged with intrarectal administration of acetic acid.
Topics: Acetic Acid; Amine Oxidase (Copper-Containing); Analysis of Variance; Animals; Caspase 3; Claudin-1; | 2014 |
Study on analgesic and anti-inflammatory properties of Cordia myxa fruit hydro-alcoholic extract.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Cordia; Disease Models | 2013 |
Role of spinal GABAA receptors in pudendal inhibition of nociceptive and nonnociceptive bladder reflexes in cats.
Topics: Acetic Acid; Animals; Cats; Disease Models, Animal; Electric Stimulation; Female; GABA Antagonists; | 2014 |
The in vivo and in vitro study of polysaccharides from a two-herb formula on ulcerative colitis and potential mechanism of action.
Topics: Acetic Acid; Amine Oxidase (Copper-Containing); Animals; Astragalus propinquus; Colitis, Ulcerative; | 2014 |
Anti-allergic rhinitis effect of caffeoylxanthiazonoside isolated from fruits of Xanthium strumarium L. in rodent animals.
Topics: Acetic Acid; Analgesics; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Caffeic Acids; Dis | 2014 |
Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin, V1A receptor in primary sensory neurons.
Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Action Potentials; Analge | 2014 |
The effects of bilateral bipolar sacral neurostimulation on urinary bladder activity during filling before and after irritation in a rat model.
Topics: Acetic Acid; Animals; Disease Models, Animal; Female; Rats, Sprague-Dawley; Reflex; Spinal Cord Stim | 2015 |
δ-Amyrone, a specific inhibitor of cyclooxygenase-2, exhibits anti-inflammatory effects in vitro and in vivo of mice.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Cells, Cultured; Cyclooxygenase 2; Dermatitis, Conta | 2014 |
Synthesis and analgesic effects of μ-TRTX-Hhn1b on models of inflammatory and neuropathic pain.
Topics: Acetic Acid; Analgesics; Animals; Disease Models, Animal; Formaldehyde; HEK293 Cells; Humans; Inflam | 2014 |
Modulating effect of Biophytum sensitivum extract on rats with acetic acid-induced ulcerative colitis.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Disease Models, Animal; Dose-Response Relationship, Drug; | 2014 |
Epidermal growth factor upregulates serotonin transporter and its association with visceral hypersensitivity in irritable bowel syndrome.
Topics: Acetic Acid; Animals; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme In | 2014 |
Uterine cytokine profile in a rat model of endometritis.
Topics: Acetic Acid; Animals; Cytokines; Disease Models, Animal; Endometritis; Escherichia coli Infections; | 2015 |
The protective effect of Echinacea spp. (Echinacea angustifolia and Echinacea purpurea) in a rat colitis model induced by acetic acid.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Disease Models, Animal; Echinacea; Interleukin-1beta; Mal | 2014 |
Propranolol, but not naloxone, enhances spinal reflex bladder activity and reduces pudendal inhibition in cats.
Topics: Acetic Acid; Adrenergic beta-Antagonists; Animals; Cats; Disease Models, Animal; Electric Stimulatio | 2015 |
Synthesis, hydrolysis kinetics and pharmacological evaluation of aceclofenac prodrugs.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2015 |
Antipyretic and antinociceptive potential of extract/fractions of Potentilla evestita and its isolated compound, acacetin.
Topics: Acetic Acid; Analgesics; Animals; Antipyretics; Disease Models, Animal; Fever; Flavones; Male; Mice, | 2014 |
Antinociceptive effect of botulinum toxin type A on experimental abdominal pain.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Botulinum Toxins, Type A; Capsaicin; Colitis; Dise | 2014 |
Terminalia catappa L.: a medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Caribbean Region; Disease Models, An | 2015 |
Comparison of the anti-ulcer activity between the crude and bran-processed Atractylodes lancea in the rat model of gastric ulcer induced by acetic acid.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Atractylodes; Dietary Fiber; Dinoprostone; Disease M | 2015 |
Distinct interactions of cannabidiol and morphine in three nociceptive behavioral models in mice.
Topics: Acetic Acid; Acute Pain; Analgesics, Opioid; Animals; Behavior, Animal; Cannabidiol; Disease Models, | 2015 |
Effects of traditional Chinese herbal medicine San-Huang-Xie-Xin-Tang on gastrointestinal motility in mice.
Topics: Acetic Acid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herba | 2015 |
Role of spinal metabotropic glutamate receptor 5 in pudendal inhibition of the nociceptive bladder reflex in cats.
Topics: Acetic Acid; Action Potentials; Animals; Cats; Disease Models, Animal; Excitatory Amino Acid Antagon | 2015 |
Extracts of Leptadenia hastata Leaf, a Famine Food and Traditional Remedy for Furuncles, Suppress Inflammation in Murine Models.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Apocynaceae; Arthritis; Capillary Permeability; Carr | 2016 |
Intraperitoneal administration of butyrate prevents the severity of acetic acid colitis in rats.
Topics: Acetic Acid; Administration, Oral; Administration, Rectal; Animals; Butyric Acid; Colitis, Ulcerativ | 2015 |
Functional restoration of exhausted CD4(+) and CD8(+) T cells in chronic viral infection by vinegar-processed flos of Daphne genkwa.
Topics: Acetic Acid; Animals; Arenaviridae Infections; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocyte | 2015 |
Design and Synthesis of Mannich bases as Benzimidazole Derivatives as Analgesic Agents.
Topics: Acetic Acid; Analgesics; Animals; Benzimidazoles; Diclofenac; Disease Models, Animal; Drug Evaluatio | 2015 |
Neurophysiological modeling of bladder afferent activity in the rat overactive bladder model.
Topics: Acetic Acid; Animals; Disease Models, Animal; Male; Models, Neurological; Neurons, Afferent; Rats; R | 2015 |
Production of novel vinegar having antioxidant and anti-fatigue activities from Salicornia herbacea L.
Topics: Acetic Acid; Animals; Antioxidants; Chenopodiaceae; Disease Models, Animal; Exercise Tolerance; Fati | 2016 |
Fatty acid carbon is essential for dNTP synthesis in endothelial cells.
Topics: Acetic Acid; Adenosine Triphosphate; Animals; Blood Vessels; Carbon; Carnitine O-Palmitoyltransferas | 2015 |
Effect of fruit vinegars on liver damage and oxidative stress in high-fat-fed rats.
Topics: Acetic Acid; Animals; Antioxidants; Body Weight; Diet, High-Fat; Dietary Fats; Disease Models, Anima | 2016 |
Ellagic acid enhances the antinociceptive action of carbamazepine in the acetic acid writhing test with mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carbamazepine; Disease | 2016 |
Kaempferol, a dietary flavonoid, ameliorates acute inflammatory and nociceptive symptoms in gastritis, pancreatitis, and abdominal pain.
Topics: Abdominal Pain; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ceruletide; | 2015 |
Embelin lipid nanospheres for enhanced treatment of ulcerative colitis - Preparation, characterization and in vivo evaluation.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Benzoquinones; Chemistry, Pharmaceutical; Coconut Oi | 2015 |
Evaluation of the protective effect of Pterocarpus marsupium on acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Disease Models, A | 2015 |
Analgesic and anti-inflammatory effects of hydroalcoholic extract isolated from Semen vaccariae.
Topics: Acetic Acid; Administration, Oral; Alcohols; Analgesics; Animals; Anti-Inflammatory Agents; Capillar | 2015 |
Protective effect of cavidine on acetic acid-induced murine colitis via regulating antioxidant, cytokine profile and NF-κB signal transduction pathways.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Berberine Alkaloids; Colitis, Ulcerative; Col | 2015 |
The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis.
Topics: Acetic Acid; Aminopyridines; Animals; Colitis; Disease Models, Animal; Intestinal Mucosa; Intracellu | 2015 |
Oral Administration of Lipopolysaccharide of Acetic Acid Bacteria Protects Pollen Allergy in a Murine Model.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Allergic Agents; Disease Models, Animal; Female; Fo | 2015 |
Observing Anti-inflammatory and Anti-nociceptive Activities of Glycyrrhizin Through Regulating COX-2 and Pro-inflammatory Cytokines Expressions in Mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Cyc | 2015 |
Discriminative stimulus effects of morphine and oxycodone in the absence and presence of acetic acid in male and female C57Bl/6 mice.
Topics: Acetic Acid; Acute Pain; Analgesics, Opioid; Analysis of Variance; Animals; Conditioning, Operant; D | 2015 |
Potential analgesic effects of a novel N-acylethanolamine acid amidase inhibitor F96 through PPAR-α.
Topics: Acetic Acid; Amidohydrolases; Analgesics; Animals; Disease Models, Animal; Ear; Edema; Enzyme Inhibi | 2015 |
Analgesic and Anti-Inflammatory Properties of Gelsolin in Acetic Acid Induced Writhing, Tail Immersion and Carrageenan Induced Paw Edema in Mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Diclofenac; Disease Models, | 2015 |
Anti-inflammatory effects of nesfatin-1 in rats with acetic acid - induced colitis and underlying mechanisms.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Calcium-Binding Proteins; Colitis; Dis | 2015 |
Protective Effect of Ocimum basilicum Essential Oil Against Acetic Acid-Induced Colitis in Rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Iran; Male; Ocimum basilicum; Oils, Vo | 2016 |
Bacopa monnieri: An evaluation of antihyperglycemic and antinociceptive potential of methanolic extract of whole plants.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Bacopa; Blood Glucose; Disease Models, Animal; Dos | 2015 |
Ototoxicity of acetic acid on the guinea pig cochlea.
Topics: Acetic Acid; Action Potentials; Administration, Topical; Animals; Auditory Threshold; Cochlea; Cochl | 2015 |
Gastroprotective effects of thymol on acute and chronic ulcers in rats: The role of prostaglandins, ATP-sensitive K(+) channels, and gastric mucus secretion.
Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relation | 2016 |
Effect of tibial nerve stimulation on bladder afferent nerve activity in a rat detrusor overactivity model.
Topics: Acetic Acid; Animals; Disease Models, Animal; Electrophysiological Phenomena; Humans; Lumbosacral Pl | 2016 |
Protective Role of Curcumin and Flunixin Against Acetic Acid-Induced Inflammatory Bowel Disease via Modulating Inflammatory Mediators and Cytokine Profile in Rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Clonixin; Colon; Curcumi | 2015 |
Vinegar Treatment Prevents the Development of Murine Experimental Colitis via Inhibition of Inflammation and Apoptosis.
Topics: Acetic Acid; Animals; Apoptosis; Colitis, Ulcerative; Colon; Cytokines; Disease Models, Animal; Huma | 2016 |
Evaluation of antinociceptive and antidiarrhoeal properties of Manilkara zapota leaves in Swiss albino mice.
Topics: Acetic Acid; Analgesics; Animals; Antidiarrheals; Behavior, Animal; Castor Oil; Diarrhea; Disease Mo | 2016 |
Metabolite Profiling Reveals the Effect of Dietary Rubus coreanus Vinegar on Ovariectomy-Induced Osteoporosis in a Rat Model.
Topics: Acetic Acid; Alendronate; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; | 2016 |
The traditional Japanese medicine hangeshashinto alleviates oral ulcer-induced pain in a rat model.
Topics: Acetic Acid; Administration, Topical; Analgesics; Animals; Disease Models, Animal; Drugs, Chinese He | 2016 |
Effects of cannabinoid receptor activation by CP55,940 on normal bladder function and irritation-induced bladder overactivity in non-awake anaesthetised rats.
Topics: Acetic Acid; Administration, Intravesical; Animals; Cannabinoid Receptor Agonists; Cyclohexanols; Di | 2016 |
Involvement of opioid receptors in the systemic and peripheral antinociceptive actions of montelukast in the animal models of pain.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Behavior, Animal; Cyclopropanes; Disease Models, Animal; | 2016 |
Anti-inflammatory effects of royal poinciana through inhibition of toll-like receptor 4 signaling pathway.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Cyclooxygenase | 2016 |
Reprogramming of hepatic fat accumulation and 'browning' of adipose tissue by the short-chain fatty acid acetate.
Topics: Acetic Acid; Adipocytes, Brown; Adipogenesis; Adipose Tissue; Adipose Tissue, White; Animals; Diseas | 2016 |
Antihyperalgesic effect of [(±)-(2,4,6-cis)-4-chloro-6-(naphthalen-1-yl)-tetrahydro-2H-pyran-2-yl]methanol: participation of the NO/cGMP/KATP pathway and κ-opioid receptor.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Cyclic GMP; Disease Models, Animal; Dose-Res | 2016 |
Non-neuronal, but atropine-sensitive ileal contractile responses to short-chain fatty acids: age-dependent desensitization and restoration under inflammatory conditions in mice.
Topics: Acetic Acid; Acetylcholine; Acetylcholinesterase; Age Factors; Animals; Atropine; Choline O-Acetyltr | 2016 |
Studies on anti-inflammatory and analgesic properties of Lactobacillus rhamnosus in experimental animal models.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; Diclofenac; Dise | 2016 |
Quantitative evaluation of striated muscle injury by multiscale blob features method.
Topics: Acetic Acid; Animals; Disease Models, Animal; Microwaves; Muscle, Striated; Swine | 2016 |
Antinociceptive, antioxidant and phytochemical studies of Pakistani medicinal plants.
Topics: Acetic Acid; Analgesics; Animals; Antioxidants; Biphenyl Compounds; Chenopodium; Disease Models, Ani | 2016 |
Intratesticular Bradykinin Involvement in Rat Testicular Pain Models.
Topics: Acetic Acid; Animals; Behavior, Animal; Bradykinin; Bradykinin B2 Receptor Antagonists; Disease Mode | 2018 |
Medical ozone treatment ameliorates the acute distal colitis in rat.
Topics: Acetic Acid; Acute Disease; Animals; Colitis, Ulcerative; Colon; Disease Models, Animal; Immunohisto | 2016 |
Isobolographic Analysis of the Interaction Between Tapentadol and Ketorolac in a Mouse Model of Visceral Pain.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, A | 2016 |
[Anti-obesogenic effect of apple cider vinegar in rats subjected to a high fat diet].
Topics: Acetic Acid; Animals; Antioxidants; Body Weight; Diet, High-Fat; Disease Models, Animal; Male; Malus | 2016 |
Diminazene aceturate, an angiotensin-converting enzyme II activator, prevents gastric mucosal damage in mice: Role of the angiotensin-(1-7)/Mas receptor axis.
Topics: Acetic Acid; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, An | 2016 |
Mentha longifolia protects against acetic-acid induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Colitis; Colon; Cyclohexan | 2016 |
Hydroethanolic extract of Baccharis trimera promotes gastroprotection and healing of acute and chronic gastric ulcers induced by ethanol and acetic acid.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Baccharis; Cytoprotection; Disease Models, An | 2016 |
Tabernaemontana catharinensis ethyl acetate fraction presents antinociceptive activity without causing toxicological effects in mice.
Topics: Acetates; Acetic Acid; Administration, Oral; Analgesics; Animals; Apocynaceae; Behavior, Animal; Cap | 2016 |
Inhibition of neuronal and inducible nitric oxide synthase does not affect the analgesic effects of NMDA antagonists in visceral inflammatory pain.
Topics: Acetic Acid; Analgesics; Animals; Calcium Channel Blockers; Disease Models, Animal; Dizocilpine Male | 2016 |
Anti-inflammatory and analgesic effects of Bi-yuan-ling granules.
Topics: Acetic Acid; Acute Lung Injury; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Chloroge | 2016 |
Evidence of anti-inflammatory and antinociceptive activities of Plinia edulis leaf infusion.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Chemotaxi | 2016 |
Development of enteric-coated microspheres of embelin for their beneficial pharmacological potential in ulcerative colitis.
Topics: Acetic Acid; Animals; Benzoquinones; Coated Materials, Biocompatible; Colitis, Ulcerative; Disease M | 2017 |
Piper umbellatum L.: A medicinal plant with gastric-ulcer protective and ulcer healing effects in experimental rodent models.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Catalase; Chronic Dis | 2016 |
Sacral neuromodulation of nociceptive bladder overactivity in cats.
Topics: Acetic Acid; Animals; Cats; Disease Models, Animal; Electric Stimulation Therapy; Female; Male; Refl | 2017 |
Fruit vinegars attenuate cardiac injury via anti-inflammatory and anti-adiposity actions in high-fat diet-induced obese rats.
Topics: Acetic Acid; Adiposity; Animals; Anti-Inflammatory Agents; Anti-Obesity Agents; Biomarkers; Body Wei | 2017 |
Beneficial effect of Amorphophallus paeoniifolius tuber on experimental ulcerative colitis in rats.
Topics: Acetic Acid; Alkaline Phosphatase; Amorphophallus; Animals; Anti-Inflammatory Agents; Biomarkers; Ca | 2017 |
Anti-inflammatory, analgesic and antioxidant activities of 3,4-oxo-isopropylidene-shikimic acid.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Cotton Fiber; | 2016 |
Antinociceptive and anticonvulsant effects of the monoterpene linalool oxide.
Topics: Acetic Acid; Acyclic Monoterpenes; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Cyclohexa | 2017 |
Beta-cyclodextrin enhanced gastroprotective effect of (-)-linalool, a monoterpene present in rosewood essential oil, in gastric lesion models.
Topics: Acetic Acid; Acyclic Monoterpenes; Animals; Anti-Ulcer Agents; Antioxidants; beta-Cyclodextrins; Cyt | 2016 |
Neurotransmitter Mechanisms Underlying Sacral Neuromodulation of Bladder Overactivity in Cats.
Topics: Acetic Acid; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Cats; Disease Models, Anima | 2017 |
In vivo antinociceptive and muscle relaxant activity of leaf and bark of Buddleja asiatica L.
Topics: Acetic Acid; Analgesics; Animals; Buddleja; Disease Models, Animal; Dose-Response Relationship, Drug | 2016 |
Lumbosacral spinal segmental contributions to tibial and pudendal neuromodulation of bladder overactivity in cats.
Topics: Acetic Acid; Animals; Cats; Disease Models, Animal; Female; Male; Pudendal Nerve; Spinal Nerve Roots | 2017 |
Anti-oxidant, anti-inflammatory, analgesic and antipyretic activities of grapevine leaf extract (Vitis vinifera) in mice and identification of its active constituents by LC-MS/MS analyses.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Antipyretics; Behavior, An | 2016 |
Treatment of chemically induced oral ulcer using adipose-derived mesenchymal stem cell sheet.
Topics: Acetic Acid; Adipose Tissue; Animals; Cell Culture Techniques; Disease Models, Animal; Mesenchymal S | 2017 |
Effects of pulsed-radiofrequency neuromodulation on the rat with overactive bladder.
Topics: Acetic Acid; Animals; Disease Models, Animal; Female; Pulsed Radiofrequency Treatment; Rats; Rats, S | 2017 |
Antinociceptive effect of methanol extract of Dalbergia sissoo leaves in mice.
Topics: Acetic Acid; Analgesics; Animals; Cyclic GMP; Dalbergia; Disease Models, Animal; Drug Evaluation, Pr | 2017 |
Gut microbial degradation of organophosphate insecticides-induces glucose intolerance via gluconeogenesis.
Topics: Acetic Acid; Animals; Biomarkers; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Feces; G | 2017 |
Evaluation of acute toxicity, sedative and analgesic effects of Taverniera glabra methanolic extract on mice.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Central Nervous System; Disease Models, Animal; | 2016 |
Mild Social Stress in Mice Produces Opioid-Mediated Analgesia in Visceral but Not Somatic Pain States.
Topics: Acetic Acid; Animals; Capsaicin; Corticosterone; Cues; Disease Models, Animal; Formaldehyde; Male; M | 2017 |
A novel zebrafish-based model of nociception.
Topics: Acetic Acid; Acrolein; Analgesics, Opioid; Animals; Antineoplastic Agents, Phytogenic; Disease Model | 2017 |
Enhanced bladder capacity and reduced prostaglandin E2-mediated bladder hyperactivity in EP3 receptor knockout mice.
Topics: Acetic Acid; Animals; Dinoprostone; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout | 2008 |
Gosha-jinki-gan reduces transmitter proteins and sensory receptors associated with C fiber activation induced by acetic acid in rat urinary bladder.
Topics: Acetic Acid; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Immunohistochemistry; N | 2008 |
Quercetin: further investigation of its antinociceptive properties and mechanisms of action.
Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Capsaicin; Cholinergic Agents; Disease Models, | 2008 |
Minodronic acid, a third-generation bisphosphonate, antagonizes purinergic P2X(2/3) receptor function and exerts an analgesic effect in pain models.
Topics: Acetic Acid; Adenosine Triphosphate; Analgesics, Non-Narcotic; Animals; Bone Density Conservation Ag | 2008 |
Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat.
Topics: Acetic Acid; Analysis of Variance; Animals; Arthritis; Colitis; Cyclooxygenase Inhibitors; Cytokines | 2008 |
Acetic acid induced ulceration in rats is not affected by infection with Hymenolepis diminuta.
Topics: Acetic Acid; Animals; Disease Models, Animal; Hymenolepiasis; Hymenolepis diminuta; Male; Rats; Rats | 2009 |
Anti-inflammatory and analgesic properties in a rodent model of a (1-->3),(1-->6)-linked beta-glucan isolated from Pleurotus pulmonarius.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Capillary Permeability | 2008 |
The role of sensory C-fibers in response of vagal afferent stimulation by gastric distension in rats with experimental chronic gastric ulcer.
Topics: Acetic Acid; Afferent Pathways; Animals; Capsaicin; Chronic Disease; Disease Models, Animal; Gastric | 2008 |
Effects of pantoprazole on ulcer healing delay associated with NSAID treatment.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroid | 2009 |
Supraphysiologic extracellular pressure inhibits intestinal epithelial wound healing independently of luminal nutrient flow.
Topics: Acetic Acid; Anastomosis, Roux-en-Y; Animals; Blotting, Western; Cell Movement; Dimethyl Sulfoxide; | 2008 |
Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol.
Topics: Acetic Acid; Administration, Oral; Aging; alpha-Tocopherol; Animals; Anti-Ulcer Agents; Antioxidants | 2008 |
The effect of iNOS inhibitors and hyperbaric oxygen treatment in a rat model of experimental colitis.
Topics: Acetic Acid; Animals; Colitis; Combined Modality Therapy; Disease Models, Animal; Female; Guanidines | 2009 |
Increased glial glutamate transporter EAAT2 expression reduces visceral nociceptive response in mice.
Topics: Acetic Acid; Animals; Behavior, Animal; Ceftriaxone; Colon; Disease Models, Animal; Ethanol; Excitat | 2009 |
The voltage-gated sodium channel Nav1.9 is required for inflammation-based urinary bladder dysfunction.
Topics: Acetic Acid; Animals; Antirheumatic Agents; Cyclophosphamide; Cystitis; Dinoprostone; Disease Models | 2009 |
The analgesic and anti-inflammatory activities of the extract of Albizia lebbeck in animal model.
Topics: Acetic Acid; Administration, Oral; Albizzia; Analgesics; Animals; Anti-Inflammatory Agents; Carragee | 2009 |
Anti-inflammatory phenylpropanoid glycosides from Clerodendron trichotomum leaves.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Capillary Permeability; Carragee | 2009 |
Anti-inflammatory properties of cryptolepine.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2009 |
Filicene obtained from Adiantum cuneatum interacts with the cholinergic, dopaminergic, glutamatergic, GABAergic, and tachykinergic systems to exert antinociceptive effect in mice.
Topics: Acetic Acid; Adiantum; Analgesics; Animals; Capsaicin; Disease Models, Animal; Dose-Response Relatio | 2009 |
Analgesic activity of myricetin isolated from Myrica rubra Sieb. et Zucc. leaves.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Din | 2009 |
Involvement of glutamate and cytokine pathways on antinociceptive effect of Pfaffia glomerata in mice.
Topics: Acetic Acid; Amaranthaceae; Analgesics; Animals; Behavior, Animal; Cycloleucine; Disease Models, Ani | 2009 |
Antinociceptive activity of Amaranthus spinosus in experimental animals.
Topics: Acetic Acid; Amaranthus; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carr | 2009 |
Anti-inflammatory and analgesic effects of ethanol and aqueous extracts of Pterocephalus hookeri (C.B. Clarke) Höeck.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Dip | 2009 |
In vitro and in vivo anti-Helicobacter pylori activity of Calophyllum brasiliense Camb.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Brazil; Calophyllum; Dinoprostone; D | 2009 |
The analgesic effect of decursinol.
Topics: Acetaminophen; Acetic Acid; Analgesics; Angelica; Animals; Aspirin; Benzopyrans; Butyrates; Disease | 2009 |
Antinociceptive effects of (O-methyl)-N-benzoyl tyramine (riparin I) from Aniba riparia (Nees) Mez (Lauraceae) in mice.
Topics: Acetic Acid; Administration, Oral; Analgesics; Analgesics, Opioid; Animals; Arginine; Behavior, Anim | 2009 |
Targeting pain-depressed behaviors in preclinical assays of pain and analgesia: drug effects on acetic acid-depressed locomotor activity in ICR mice.
Topics: Acetic Acid; Analgesia; Analgesics; Animals; Behavior, Animal; Benzene Derivatives; Caffeine; Diseas | 2009 |
Synthesis of novel 1,3,4-oxadiazole derivatives and their biological properties.
Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Carrageenan; Dise | 2009 |
Analgesic and anti-inflammatory activities of ethanol root extract of Mahonia oiwakensis in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Berberine Alkaloids; C | 2009 |
Anti-nociceptive and anti-inflammatory activity of sophocarpine.
Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carra | 2009 |
Evaluation of the antiangiogenic, anti-inflammatory, and antinociceptive activities of morin.
Topics: Acetic Acid; Analgesics; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Behavior, Anima | 2010 |
Metabolic acetate therapy for the treatment of traumatic brain injury.
Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Animals; Aspartic Acid; Brain; Brain Injuries; Disease Mod | 2010 |
Social approach to pain in laboratory mice.
Topics: Acetic Acid; Analysis of Variance; Animals; Constriction; Disease Models, Animal; Female; Male; Mice | 2010 |
Behavioral and urological evaluation of a testicular pain model.
Topics: Acetic Acid; Animals; Behavior, Animal; Capsaicin; Disease Models, Animal; Indomethacin; Male; Nerve | 2010 |
Differential vulnerabilities of urethral afferents in diabetes and discovery of a novel urethra-to-urethra reflex.
Topics: Acetic Acid; Animals; Capsaicin; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Respo | 2010 |
A prolonged protein kinase C-mediated, opioid-related antinociceptive effect of st John's Wort in mice.
Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Anthracenes; Chromatography, High Pressure Liq | 2010 |
Synthesis and biological evaluation of [1,2,4]triazino[4,3-a] benzimidazole acetic acid derivatives as selective aldose reductase inhibitors.
Topics: Acetic Acid; Aldehyde Reductase; Animals; Benzimidazoles; Cataract; Disease Models, Animal; Enzyme I | 2010 |
Anti-inflammatory and anti-arthritic activity of total flavonoids of the roots of Sophora flavescens.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Behavior, Animal; Cell Line; | 2010 |
In vitro and in vivo activities of the novel anticytomegalovirus compound AIC246.
Topics: Acetic Acid; Animals; Antiviral Agents; Cell Line; Cells, Cultured; Cytomegalovirus; Cytomegalovirus | 2010 |
Assessment of anti-inflammatory and antinociceptive activities of Olea europaea L.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Capillary Permeability; C | 2010 |
Anti-inflammatory properties of red ginger (Zingiber officinale var. Rubra) extract and suppression of nitric oxide production by its constituents.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Arthritis; Behavior, Animal; Cell Line; Dinoprostone | 2010 |
Granisetron ameliorates acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Biguanides; Colitis; Colon; Dexamethasone; Disease M | 2010 |
Preliminary studies on the antinociceptive activity of Vaccinium ashei berry in experimental animal models.
Topics: Acetic Acid; Analgesics; Animals; Anthocyanins; Blueberry Plants; Diclofenac; Disease Models, Animal | 2010 |
[Influence of honey, royal jelly and propolis on accelerating acetate healing of experimental gastric ulcers in rats].
Topics: Acetic Acid; Animals; Anti-Infective Agents; Chronic Disease; Disease Models, Animal; Fatty Acids; H | 2009 |
Acetic acid bacterial lipids improve cognitive function in dementia model rats.
Topics: Acetic Acid; Acetobacter; Animals; Cognition; Dementia; Disease Models, Animal; Lipids; Male; Maze L | 2010 |
The pharmacological activities of Compound Salvia Plebeia Granules on treating urinary tract infection.
Topics: Acetic Acid; Analgesics; Animals; Anti-Infective Agents, Urinary; Behavior, Animal; Carrageenan; Dis | 2010 |
Effects of lansoprazole on the expression of VEGF and cellular proliferation in a rat model of acetic acid-induced gastric ulcer.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Anti-Ulcer Agents; Cell Cycle; Cell P | 2010 |
Antinociceptive, genotoxic and histopathological study of Heliopsis longipes S.F. Blake in mice.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Asteraceae; Behavior, Animal; Brain; Chromat | 2010 |
Antipyretic, analgesic, anti-inflammatory and antioxidant activities of two major chromenes from Melicope lunu-ankenda.
Topics: Acetic Acid; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Antioxidants; | 2010 |
Antinociceptive and anti-inflammatory activities of lectin from marine red alga Pterocladiella capillacea.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Disease M | 2010 |
Altered expression of a putative progenitor cell marker DCAMKL1 in the rat gastric mucosa in regeneration, metaplasia and dysplasia.
Topics: Acetic Acid; Animals; Biomarkers; Cell Proliferation; Disease Models, Animal; Doublecortin Protein; | 2010 |
Analgesic effects of the ethanolic extract from Magnolia ovata (Magnoliaceae) trunk bark and of N-acetylxylopine, a semi-synthetic analogue of xylopine.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Aporphines; Carrageenan; Disease Models, | 2011 |
Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Colitis, Ulcerative; Co | 2011 |
The effect of exopolysaccharide-producing probiotic strains on gut oxidative damage in experimental colitis.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Female; Lactobacillus delbrueckii; Lip | 2011 |
Antinociceptive and anti-inflammatory effects of Costus spicatus in experimental animals.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Costus; Disease Models, Ani | 2010 |
Assessment of antinociceptive, anti-inflammatory and antioxidant properties of Cymbopogon winterianus leaf essential oil.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Carrag | 2010 |
Synthesis and preliminary biological evaluation of capsaicin derivatives as potential analgesic drugs.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cap | 2010 |
Synthesis and pharmacological evaluation of novel 1-(2-(benzoyl-substituted-2-phenyl-1H-indol-5-carbony) hydrazinyloxy) vinyl nitrate derivatives as potent non-ulcerogenic, analgesic and anti-inflammatory agents.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dis | 2010 |
Chemical structure and selected biological properties of a glucomannan from the lichenized fungus Heterodermia obscurata.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascomycota; Brazil; Disease Models, A | 2010 |
Elucidation of possible mechanism of analgesic action of Valeriana wallichii DC chemotype (patchouli alcohol) in experimental animal models.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asp | 2010 |
Protective effect of Lactobacillus casei strain Shirota against lethal infection with multi-drug resistant Salmonella enterica serovar Typhimurium DT104 in mice.
Topics: Acetic Acid; Animals; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Lacticaseibacill | 2011 |
Ginger extract and polaprezinc exert gastroprotective actions by anti-oxidant and growth factor modulating effects in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Carnosine; Chemokines; Cytokines; Cytoprotect | 2010 |
A novel TRPV1 receptor antagonist JNJ-17203212 attenuates colonic hypersensitivity in rats.
Topics: Acetic Acid; Administration, Oral; Aminopyridines; Animals; Colon; Disease Models, Animal; Dose-Resp | 2010 |
Extrasegmental analgesia of heterotopic electroacupuncture stimulation on visceral pain rats.
Topics: Acetic Acid; Acupuncture Points; Afferent Pathways; Analgesia; Animals; Capsaicin; Disease Models, A | 2011 |
Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Biomarkers; Cisapride; Disease Models | 2011 |
Protective effect of embelin against acetic acid induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Benzoquinones; Colitis, Ulcerative; Di | 2011 |
Antinociceptive effect of extract of Emilia sonchifolia in mice.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Asteraceae; Behavior, Animal; Brazil; Disease Models, Anim | 2011 |
Role of bone marrow-derived monocytes/macrophages in the repair of mucosal damage caused by irradiation and/or anticancer drugs in colitis model.
Topics: Acetic Acid; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Biomarkers; Bone Marro | 2010 |
Evaluation of the antipeptic ulcer activity of the leaf extract of Plantago lanceolata L. in rodents.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Ethiopi | 2011 |
Antinociceptive activity of methanolic extract of leaves of Achyranthes aspera Linn. (Amaranthaceae) in animal models of nociception.
Topics: Acetic Acid; Amaranthaceae; Analgesics; Animals; Disease Models, Animal; Female; Indicators and Reag | 2010 |
Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae).
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Bicyclic Monoterpenes; Brazil; Bridged Bicyclo Compounds; C | 2011 |
Heme oxygenase/carbon monoxide-biliverdin pathway may be involved in the antinociceptive activity of etoricoxib, a selective COX-2 inhibitor.
Topics: Acetic Acid; Analgesics; Animals; Biliverdine; Carbon Monoxide; Cyclooxygenase 2 Inhibitors; Disease | 2011 |
The analgesic effects and mechanisms of orally administered eugenol.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Behavior, Animal; Brain; Disease Models, Ani | 2011 |
Protective effect of aqueous extract of Bombax malabaricum DC on experimental models of inflammatory bowel disease in rats and mice.
Topics: Acetic Acid; Animals; Bombax; Colitis; Disease Models, Animal; Female; India; Indomethacin; Inflamma | 2011 |
Triterpenes involved in the anti-inflammatory effect of ethanolic extract of Pterodon emarginatus Vogel stem bark.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Chemical Fractionation; Croton Oil; Dise | 2012 |
Analgesic effects and anti-inflammatory properties of the crude methanolic extract of Schwenckia americana Linn (Solanaceae).
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Re | 2011 |
Anti-inflammatory and analgesic activities of ethanolic extract of Sphaeranthus indicus Linn.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Asteraceae; Carrageenan; Disease Models, | 2011 |
Anti-inflammatory and analgesic activity of protocatechuic acid in rats and mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2011 |
Anti-inflammatory and anti-nociceptive activities of Sipunculus nudus L. extract.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeabi | 2011 |
Antioxidant, analgesic, and anti-inflammatory activities of the ethanolic extracts of Taxillus liquidambaricola.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Benzothiazoles; Biphenyl C | 2011 |
Antinociceptive and hypnotic properties of Celastrus orbiculatus.
Topics: Acetic Acid; Animals; Celastrus; Disease Models, Animal; Dose-Response Relationship, Drug; Female; F | 2011 |
The analgesic and anti-rheumatic effects of Thladiantha dubia fruit crude polysaccharide fraction in mice and rats.
Topics: Acetic Acid; Analgesics; Animals; Ankle Joint; Antirheumatic Agents; Arthritis, Rheumatoid; Cucurbit | 2011 |
Formulation and evaluation of in situ gelling systems for intranasal administration of gastrodin.
Topics: Absorption; Acetic Acid; Adhesiveness; Administration, Intranasal; Animals; Anura; Benzyl Alcohols; | 2011 |
Experimental study on anti-inflammatory activity of a TCM recipe consisting of the supercritical fluid CO2 extract of Chrysanthemum indicum, Patchouli Oil and Zedoary Turmeric Oil in vivo.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carbon Dioxide; Carrageenan; | 2012 |
Vitamin E has a dual effect of anti-inflammatory and antioxidant activities in acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Antioxidants; Colitis, Ulcerative; Colon; Disease Models, Animal; Female; Inte | 2011 |
Milnacipran is active in models of irritable bowel syndrome and abdominal visceral pain in rodents.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Butyrates; Cyclopropanes; Disease Models, Animal; | 2011 |
Involvement of metabotropic glutamate receptor 5 in pudendal inhibition of nociceptive bladder activity in cats.
Topics: Acetic Acid; Animals; Cats; Disease Models, Animal; Female; Pain; Pudendal Nerve; Pyridines; Recepto | 2011 |
Antipyretic, anti-inflammatory and analgesic properties of nilavembu kudineer choornam: a classical preparation used in the treatment of chikungunya fever.
Topics: Acetic Acid; Animals; Carrageenan; Case-Control Studies; Disease Models, Animal; Dose-Response Relat | 2011 |
Anti-inflammatory activities and mechanisms of action of the petroleum ether fraction of Rosa multiflora Thunb. hips.
Topics: Acetic Acid; Alkanes; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Diseas | 2011 |
Diuretic, anti-inflammatory, and analgesic activities of the ethanol extract from Cynoglossum lanceolatum.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Boraginaceae; Carrageenan; Disease Model | 2012 |
The central versus peripheral antinociceptive effects of μ-opioid receptor agonists in the new model of rat visceral pain.
Topics: Acetic Acid; Analgesics, Opioid; Analysis of Variance; Animals; Disease Models, Animal; Dose-Respons | 2012 |
Analgesic and anti-inflammatory activity and pharmacokinetics of alkaloids from seeds of Strychnos nux-vomica after transdermal administration: effect of changes in alkaloid composition.
Topics: Acetic Acid; Administration, Cutaneous; Alkaloids; Analgesics; Animals; Anti-Inflammatory Agents; Be | 2012 |
Wound healing and anti-inflammatory activities of the Michauxia L'Hérit (Campanulaceae) species native to Turkey.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Campanulaceae; Cap | 2012 |
Wound healing and anti-inflammatory properties of Ranunculus pedatus and Ranunculus constantinapolitanus: a comparative study.
Topics: Acetic Acid; Animals; Anti-Infective Agents; Capillary Permeability; Disease Models, Animal; Hydroxy | 2012 |
Appraisal on the wound healing and anti-inflammatory activities of the essential oils obtained from the cones and needles of Pinus species by in vivo and in vitro experimental models.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Capillary Permeability; Disease Models, Animal; Enzy | 2012 |
Isolation of active constituents from cherry laurel (Laurocerasus officinalis Roem.) leaves through bioassay-guided procedures.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Biological Assay; Capilla | 2012 |
In vitro and in vivo evaluation of ibuprofen-paeonol conjugate.
Topics: Acetic Acid; Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceuti | 2011 |
[GC-MS analysis and analgesic activity of essential oil from fresh rhizoma of Cyperus rotundus].
Topics: Acetic Acid; Analgesics; Animals; Cyperus; Disease Models, Animal; Drugs, Chinese Herbal; Gas Chroma | 2011 |
Indomethacin uptake into poly(2-hydroxyethyl methacrylate-co-3,9-divinyl-2,4,8,10-tetraoxaspiro [5.5]-undecane) network: In vitro and in vivo controlled release study.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Behavior, Animal; Chemistry, Pharmaceutical; | 2012 |
Acetic acid- and phenyl-p-benzoquinone-induced overt pain-like behavior depends on spinal activation of MAP kinases, PI(3)K and microglia in mice.
Topics: Acetic Acid; Androstadienes; Animals; Anthracenes; Benzoquinones; Disease Models, Animal; Flavonoids | 2012 |
Anti-nociceptive and anti-inflammatory properties of the ethanolic extract of Lagenaria breviflora whole fruit in rat and mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cucurbitaceae; Disease Mode | 2011 |
Evaluation of antinociceptive effects of Crassocephalum bauchiense Hutch (Asteraceae) leaf extract in rodents.
Topics: Acetic Acid; Administration, Oral; Alkaloids; Analgesics; Analgesics, Opioid; Animals; Asteraceae; B | 2012 |
Antiinflammatory, analgesic and antioxidant activities of Cyathula prostrata (Linn.) Blume (Amaranthaceae).
Topics: Acetic Acid; Amaranthaceae; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic | 2012 |
Inhibition of acute experimental colitis by a crude extract and diets containing seeds of Garcinia kola (heckel).
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Di | 2010 |
The anti-inflammatory and antinociceptive properties of the chloroform fraction from Phyllanthus niruri plant is mediated via the peripheral nervous system.
Topics: Acetic Acid; Albumins; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Aspirin; Behavio | 2010 |
Analgesic and antipyretic activities of ethanol extract of Stereospermum suaveolens.
Topics: Acetaminophen; Acetic Acid; Analgesics; Animals; Antipyretics; Behavior, Animal; Bignoniaceae; Disea | 2010 |
Effect of Boswellia serrata on antioxidant status in an experimental model of colitis rats induced by acetic acid.
Topics: Acetic Acid; Anal Canal; Animals; Boswellia; Colitis; Colon; Disease Models, Animal; Drug Evaluation | 2012 |
Anti-inflammatory and analgesic potential of a novel steroidal derivative from Bryophyllum pinnatum.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Diclofena | 2012 |
Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: therapeutic efficacy and possible mechanisms of action.
Topics: Acetic Acid; Acute Disease; Administration, Oral; Animals; Anti-Inflammatory Agents; Apoptosis; Cell | 2012 |
Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model.
Topics: Acetic Acid; Adenocarcinoma; Administration, Topical; Animals; Antineoplastic Agents; Disease Models | 2012 |
Anti-inflammatory and analgesic activity of novel oral aspirin-loaded nanoemulsion and nano multiple emulsion formulations generated using ultrasound cavitation.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Behavior, | 2012 |
Antipyretic, analgesic and anti-inflammatory activity of Viola betonicifolia whole plant.
Topics: Acetaminophen; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Behavior, A | 2012 |
Anti-inflammatory effect of triterpene 3β, 6β, 16β-trihydroxylup-20(29)-ene obtained from Combretum leprosum Mart & Eich in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Ascitic Fluid; Capillary Permeability; C | 2012 |
Anti-nociceptive and anti-inflammatory effects of Croton crassifolius ethanol extract.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Capillaries; Carrageen | 2012 |
Effect of juice and fermented vinegar from Hovenia dulcis peduncles on chronically alcohol-induced liver damage in mice.
Topics: Acetic Acid; Alanine Transaminase; Animals; Aspartate Aminotransferases; Beverages; Disease Models, | 2012 |
Antiulcerogenic effect of Croton urucurana Baillon bark.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Croton; Disease Models, Animal; Ethanol; Female; Gastric Ac | 2012 |
Characterization of phenolic compounds and antinociceptive activity of Sempervivum tectorum L. leaf juice.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Calibration; Chromatography, High Pressure Liqui | 2012 |
Potential of Moringa oleifera root and Citrus sinensis fruit rind extracts in the treatment of ulcerative colitis in mice.
Topics: Acetic Acid; Animals; Citrus sinensis; Colitis, Ulcerative; Disease Models, Animal; Dose-Response Re | 2012 |
Anti-inflammatory and analgesic properties of the ethanolic extract of Cnidoscolus aconitifolius in rats and mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Disease M | 2011 |
Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors.
Topics: 1-Deoxynojirimycin; Acetic Acid; Animals; Apoptosis; Disease Models, Animal; Enzyme Inhibitors; Fumo | 2013 |
Curative effect of Terminalia chebula extract on acetic acid-induced experimental colitis: role of antioxidants, free radicals and acute inflammatory marker.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Biomarkers; Colitis, Ulcerative; Disease Mode | 2013 |
Enhanced excitability of guinea pig inferior mesenteric ganglion neurons during and following recovery from chemical colitis.
Topics: Acetic Acid; Action Potentials; Animals; Anthracenes; Colitis; Disease Models, Animal; Electrophysio | 2012 |
Evaluation of anti-nociceptive activity of methanolic extract of Tecomaria capensis Thunb. (Bignoniaceae) leaves in rats.
Topics: Acetic Acid; Analgesics; Animals; Aspirin; Bignoniaceae; Disease Models, Animal; Dose-Response Relat | 2012 |
Combination of foot stimulation and tramadol treatment reverses irritation induced bladder overactivity in cats.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Cats; Combined Modality Therapy; Disease Models, Animal; D | 2012 |
Antinociceptive activity of carvacrol (5-isopropyl-2-methylphenol) in mice.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Arginine; Behavior, Animal; Cymenes; Disease Model | 2012 |
Analgesic effects of the non-nitrogen-containing bisphosphonates etidronate and clodronate, independent of anti-resorptive effects on bone.
Topics: Acetic Acid; Analgesics; Animals; Capsaicin; Clodronic Acid; Corticosterone; Diphosphonates; Disease | 2013 |
Intratumoral acetic acid injection eradicates human prostate cancer tumors in a murine model.
Topics: Acetic Acid; Animals; Carcinoma; Case-Control Studies; Disease Models, Animal; Humans; Injections, I | 2013 |
Effect of marine mangrove Avicennia marina (Forssk.) Vierh against acetic acid-induced ulcerative colitis in experimental mice.
Topics: Acetic Acid; Animals; Avicennia; Colitis, Ulcerative; Colon; Disease Models, Animal; Glutathione; Gl | 2012 |
Involvement of spinal 5-HT1A receptors in isolation rearing-induced hypoalgesia in mice.
Topics: Acetic Acid; Acute Pain; Animals; Behavior, Animal; Capsaicin; Disease Models, Animal; Male; Mice; P | 2013 |
Antinociceptive effect of Lecythis pisonis Camb. (Lecythidaceae) in models of acute pain in mice.
Topics: Acetic Acid; Acute Pain; Analgesics; Animals; Arginine; Behavior, Animal; Capsaicin; Disease Models, | 2013 |
Effects of exogenous glycosaminoglycans on the histological structure of the rat bladder in experimental cystitis.
Topics: Acetic Acid; Animals; Cystitis; Disease Models, Animal; Female; Glycosaminoglycans; Mucous Membrane; | 2012 |
Anti-inflammatory, analgesic, and antioxidant activities of Pisonia aculeata: folk medicinal use to scientific approach.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Carr | 2013 |
Quercetin-loaded microcapsules ameliorate experimental colitis in mice by anti-inflammatory and antioxidant mechanisms.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Capsules; Coliti | 2013 |
Effects of vitamin D analog on bladder function and sensory signaling in animal models of cystitis.
Topics: Acetic Acid; Animals; Calcitriol; Cyclophosphamide; Cystitis; Disease Models, Animal; Female; Male; | 2013 |
Augmentation of analgesic effect of ibuprofen by alprazolam in experimental model of pain.
Topics: Acetic Acid; Acute Disease; Administration, Oral; Alprazolam; Analgesics, Non-Narcotic; Animals; Dis | 2002 |
Anti-inflammatory and antinociceptive properties of dantrolene sodium in rats and mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dantrolene; | 2002 |
Models of gastric hyperalgesia in the rat.
Topics: Acetic Acid; Animals; Avoidance Learning; Behavior, Animal; Catheterization; Disease Models, Animal; | 2002 |
Variable effects of short chain fatty acids and lactic acid in inducing intestinal mucosal injury in newborn rats.
Topics: Acetic Acid; Animals; Animals, Newborn; Butyric Acid; Colon; Disease Models, Animal; Dose-Response R | 2002 |
Prevention of acetic acid-induced colitis by desferrithiocin analogs in a rat model.
Topics: Acetic Acid; Animals; Colitis; Dihydropyridines; Disease Models, Animal; Drug Interactions; Intestin | 2003 |
Effects of trimetazidine on acetic acid-induced colitis in female Swiss rats.
Topics: Acetic Acid; Administration, Rectal; Animals; Colitis, Ulcerative; Disease Models, Animal; Female; G | 2003 |
Acetic acid-derived prostaglandin-dependent colonic adaptive cytoprotection is preserved in chronic colitis: role of cyclo-oxygenase.
Topics: Acetic Acid; Animals; Colitis; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Rela | 2003 |
Thymoquinone protects against experimental colitis in rats.
Topics: Acetic Acid; Animals; Benzoquinones; Colitis; Colon; Disease Models, Animal; Dose-Response Relations | 2003 |
The pentylenetetrazole-kindling model of epilepsy in SAMP8 mice: glial-neuronal metabolic interactions.
Topics: Acetic Acid; Age Factors; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Epilepsy; G | 2003 |
Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats.
Topics: Acetic Acid; Animals; Dinoprostone; Disease Models, Animal; Drug Administration Schedule; Fibrosis; | 2003 |
Gastroprotective and anti-inflammatory effects of resin from Protium heptaphyllum in mice and rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Brazil; Burseraceae; Capillary Pe | 2004 |
[Suppression of visceral pain by action of the low intensity polarized light on acupuncture antinociceptive points].
Topics: Acetic Acid; Acupuncture Points; Acupuncture Therapy; Animals; Disease Models, Animal; Injections, I | 2003 |
Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis.
Topics: Acetic Acid; Animals; Biomarkers; Colitis; Disease Models, Animal; Inflammation; Irritable Bowel Syn | 2003 |
Percutaneous ablation of VX2 carcinoma-induced liver tumors with use of ethanol versus acetic acid: pilot study in a rabbit model.
Topics: Acetic Acid; Animals; Carcinoma, Hepatocellular; Disease Models, Animal; Ethanol; Injections, Intral | 2004 |
Probiotic bifidobacteria protect mice from lethal infection with Shiga toxin-producing Escherichia coli O157:H7.
Topics: Acetic Acid; Animals; Bifidobacterium; Disease Models, Animal; Escherichia coli Infections; Escheric | 2004 |
Colonic ulceration and increase of neutrophil elastase activity in the acetic acid-induced colitis model in Syrian hamsters.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Cricetinae; Disease Models, Animal; Histological T | 2004 |
Intravesical botulinum toxin a administration produces analgesia against acetic acid induced bladder pain responses in rats.
Topics: Acetic Acid; Administration, Intravesical; Animals; Botulinum Toxins, Type A; Calcitonin Gene-Relate | 2004 |
Intravesical botulinum toxin a administration produces analgesia against acetic acid induced bladder pain responses in rats.
Topics: Acetic Acid; Administration, Intravesical; Animals; Botulinum Toxins, Type A; Calcitonin Gene-Relate | 2004 |
Intravesical botulinum toxin a administration produces analgesia against acetic acid induced bladder pain responses in rats.
Topics: Acetic Acid; Administration, Intravesical; Animals; Botulinum Toxins, Type A; Calcitonin Gene-Relate | 2004 |
Intravesical botulinum toxin a administration produces analgesia against acetic acid induced bladder pain responses in rats.
Topics: Acetic Acid; Administration, Intravesical; Animals; Botulinum Toxins, Type A; Calcitonin Gene-Relate | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.
Topics: Acetic Acid; Acyclic Monoterpenes; Administration, Inhalation; Administration, Oral; Analgesics; Ani | 2004 |
[Protective effect of the intraperitoneal and intragastric administration of PGP-peptide on ethanol-induced erosions and acetate-induced ulcers in rats].
Topics: Acetic Acid; Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug | 2004 |
Antitumor activity of rice-shochu post-distillation slurry and vinegar produced from the post-distillation slurry via oral administration in a mouse model.
Topics: Acetic Acid; Administration, Oral; Animals; Antineoplastic Agents; Cell Survival; Cytotoxicity, Immu | 2004 |
Increase in neurokinin-1 receptor-mediated colonic motor response in a rat model of irritable bowel syndrome.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Gastrointestinal Motility; Irritable B | 2005 |
COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions.
Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxyge | 2005 |
Ganoderma lucidum polysaccharide fractions accelerate healing of acetic acid-induced ulcers in rats.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Disease Models, Animal; Dose-Response | 2004 |
Disturbances in epithelial ionic secretion in different experimental models of colitis.
Topics: Acetic Acid; Acute Disease; Alkylating Agents; Animals; Animals, Genetically Modified; Chloramines; | 2005 |
Alterations in the heart mitochondrial proteome in a desmin null heart failure model.
Topics: Acetic Acid; Amino Acids; Animals; Aspartic Acid; Cardiomyopathy, Dilated; Databases, Protein; Desmi | 2005 |
Anti-inflammatory, anti-nociceptive and antioxidant activities of Balanites aegyptiaca (L.) Delile.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Antioxidants; Balanites; B | 2005 |
Antinociceptive and anti-inflammatory activities of Acacia pennata wild (Mimosaceae).
Topics: Acetic Acid; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non- | 2005 |
Proglumide attenuates experimental colitis in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cholecystokinin; Colitis, Ulcerative; Disease Models, Anima | 2005 |
Therapeutic effect of D-002 (abexol) on gastric ulcer induced experimentally in rats.
Topics: Acetic Acid; Acute Disease; Administration, Oral; Animals; Anti-Ulcer Agents; Antioxidants; Chronic | 2005 |
Azithromycin and erythromycin ameliorate the extent of colonic damage induced by acetic acid in rats.
Topics: Acetic Acid; Animals; Azithromycin; Colitis, Ulcerative; Colon; Disease Models, Animal; Dose-Respons | 2005 |
Anti-inflammatory and analgesic properties of water-ethanolic extract from Pothomorphe umbellata (Piperaceae) aerial parts.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Car | 2005 |
A new procedure for marinating fresh anchovies and ensuring the rapid destruction of Anisakis larvae.
Topics: Acetic Acid; Animals; Anisakis; Consumer Product Safety; Disease Models, Animal; Dose-Response Relat | 2005 |
Antinociceptive effect of leaf essential oil from Croton sonderianus in mice.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Capsaicin; Croton; Disease Models, Animal; Dose- | 2005 |
Improvement of memory impairment by (+)- and (-)-pentazocine via sigma, but not kappa opioid receptors.
Topics: Acetic Acid; Analgesics, Opioid; Analysis of Variance; Animals; Anisoles; Antipsychotic Agents; Beha | 2005 |
Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis.
Topics: Acetic Acid; Animals; Colitis; Cytokines; Disease Models, Animal; Intestinal Mucosa; Male; Necrosis; | 2005 |
Effects of exopolysaccharide-producing probiotic strains on experimental colitis in rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Female; Intestinal Mucosa; Irritants; | 2006 |
Gaultherin, a natural salicylate derivative from Gaultheria yunnanensis: towards a better non-steroidal anti-inflammatory drug.
Topics: Abdominal Pain; Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 2006 |
Role of endothelin-1-dependent up-regulation of leptin in oral mucosal repair.
Topics: Acetic Acid; Animals; Aspartic Acid Endopeptidases; Disease Models, Animal; Dose-Response Relationsh | 2005 |
Ginkgo biloba attenuates mucosal damage in a rat model of ulcerative colitis.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Disease Models, Animal; Ginkgo biloba; Glutathione; Inter | 2006 |
[Study of the effect of exceed critical extracts from Radix Aucklandiae on experimental gastric ulcer model].
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Disease Models, Animal; Drugs, Chinese Herbal; Gastric Muco | 2005 |
Somatic pain sensitivity during formation and healing of acetic acid-induced gastric ulcers in conscious rats.
Topics: Acetic Acid; Adrenal Glands; Animals; Anti-Inflammatory Agents, Non-Steroidal; Consciousness; Cortic | 2006 |
Hyperbaric oxygen enhances the efficiency of 5-aminosalicylic acid in acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Combined Modality Therapy; Disease Models, Animal; Female | 2006 |
Effects of L-carnitine on oxidant/antioxidant status in acetic acid-induced colitis.
Topics: Acetic Acid; Animals; Carnitine; Colitis, Ulcerative; Disease Models, Animal; Inflammation Mediators | 2006 |
A novel external esophageal perfusion model for reflux esophageal injury.
Topics: Acetic Acid; Animals; Apoptosis; Barrett Esophagus; Bile; Chromatography, High Pressure Liquid; Dise | 2006 |
Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice.
Topics: Acetic Acid; AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Type 2; Disease Models, Anim | 2006 |
Antinociceptive effects of tetrodotoxin (TTX) in rodents.
Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relation | 2006 |
Targeting pain-suppressed behaviors in preclinical assays of pain and analgesia: effects of morphine on acetic acid-suppressed feeding in C57BL/6J mice.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Behavior, Animal; Disease Models, Animal; Dopamine Antagon | 2006 |
Anti-inflammatory and anti-nociceptive activity of risedronate in experimental pain models in rats and mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Diphosphonates; | 2006 |
[Therapeutic effects of pravastatin on colitis induced by acetic acid and relevant mechanism: experiment with rats].
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Disease Models, Animal; Male; Malondialdehyde; Nit | 2006 |
Antinociceptive effects of synthetic chalcones obtained from xanthoxyline.
Topics: Acetaminophen; Acetic Acid; Acetophenones; Administration, Oral; Analgesics; Animals; Aspirin; Chalc | 2006 |
Anti-inflammatory effect of Diammonium Glycyrrhizinate in a rat model of ulcerative colitis.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Disease Models, Animal; Female; | 2006 |
Protective effect of comaruman, a pectin of cinquefoil Comarum palustre L., on acetic acid-induced colitis in mice.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Intestinal Mucosa; Male; Mice; Pectins | 2006 |
The effects of Gingko biloba extract on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Antioxidants; Biomarkers; Colitis; Disease Models, Animal; Fibrosis; Ginkgo bi | 2006 |
Zinc L-carnosine protects colonic mucosal injury through induction of heat shock protein 72 and suppression of NF-kappaB activation.
Topics: Acetic Acid; Administration, Rectal; Animals; Anti-Ulcer Agents; Blotting, Western; Carnosine; Colon | 2006 |
Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice.
Topics: Acetic Acid; Animals; Antioxidants; Cell Adhesion; Colitis; Colon; Disease Models, Animal; Intestina | 2006 |
Antinociceptive effects of the aqueous extract of Brugmansia suaveolens flowers in mice.
Topics: Acetic Acid; Analgesics; Analysis of Variance; Animals; Diclofenac; Disease Models, Animal; Drug Eva | 2007 |
Luminal stimuli acutely sensitize visceromotor responses to distension of the rat stomach.
Topics: Acetic Acid; Afferent Pathways; Animals; Catheterization; Disease Models, Animal; Dyspepsia; Electro | 2007 |
The vanilloid receptor initiates and maintains colonic hypersensitivity induced by neonatal colon irritation in rats.
Topics: Acetic Acid; Age Factors; Anilides; Animals; Animals, Newborn; Capsaicin; Catheterization; Cinnamate | 2007 |
Anti-inflammatory and analgesic effects of Hedychium coronarium Koen.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Ede | 2007 |
Gastroprotective effects of DA-6034, a new flavonoid derivative, in various gastric mucosal damage models.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Centra | 2007 |
Antinociceptive, anti-inflammatory and antipyretic properties of Melastoma malabathricum leaves aqueous extract in experimental animals.
Topics: Acetic Acid; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Carrageenan; C | 2006 |
Glutamine inhibits over-expression of pro-inflammatory genes and down-regulates the nuclear factor kappaB pathway in an experimental model of colitis in the rat.
Topics: Acetic Acid; Animals; Biomarkers; Colitis; Cyclooxygenase 2; Disease Models, Animal; Down-Regulation | 2007 |
GW427353 (solabegron), a novel, selective beta3-adrenergic receptor agonist, evokes bladder relaxation and increases micturition reflex threshold in the dog.
Topics: Acetic Acid; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Aniline Compounds; Anima | 2007 |
Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice.
Topics: Acetic Acid; Amines; Analgesics; Analgesics, Opioid; Analysis of Variance; Animals; Cyclohexanecarbo | 2008 |
Astrocytes may play a role in the etiology of absence epilepsy: a comparison between immature GAERS not yet expressing seizures and adults.
Topics: Acetic Acid; Aging; Animals; Astrocytes; Brain; Cell Communication; Cell Differentiation; Disease Mo | 2007 |
DAMGO and 6beta-glycine substituted 14-O-methyloxymorphone but not morphine show peripheral, preemptive antinociception after systemic administration in a mouse visceral pain model and high intrinsic efficacy in the isolated rat vas deferens.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; | 2007 |
Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics.
Topics: Acetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Anesthetics, Inha | 2007 |
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Coliti | 2008 |
Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis.
Topics: Acetic Acid; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Ethanol; G | 2008 |
Synthesis and biological evaluation of thieno[2,3-d]pyrimidine derivatives for anti-inflammatory, analgesic and ulcerogenic activity.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Disease Models, An | 2007 |
Ketorolac-dextran conjugates: synthesis, in vitro and in vivo evaluation.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Buffers; Carrag | 2007 |
Anti-inflammatory and anti-nociceptive activities of Fumaria indica whole plant extract in experimental animals.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cotto | 2007 |
P2X receptor-mediated visceral hyperalgesia in a rat model of chronic visceral hypersensitivity.
Topics: Acetic Acid; Adenosine Triphosphate; Animals; Chronic Disease; Colon; Disease Models, Animal; Hypera | 2008 |
Nefopam and ketoprofen synergy in rodent models of antinociception.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, A | 2008 |
LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Behavior, Animal; CHO Cells; Cricetinae; Cricetulus; Disea | 2008 |
99mTc(CO)3-DTMA bombesin conjugates having high affinity for the GRP receptor.
Topics: Acetates; Acetic Acid; Animals; Binding, Competitive; Bombesin; Carrier Proteins; Cations, Monovalen | 2008 |
The analgesic effect of gemcitabine in mice.
Topics: Acetic Acid; Animals; Behavior, Animal; Deoxycytidine; Disease Models, Animal; Dose-Response Relatio | 2006 |
[Influence of connexin 43 gene knockout on the analgesic effect of acupuncture in visceral pain mice].
Topics: Acetic Acid; Acupuncture Analgesia; Animals; beta-Endorphin; Connexin 43; Dinoprostone; Disease Mode | 2008 |
Intracerebroventricular injection of propionic acid, an enteric bacterial metabolic end-product, impairs social behavior in the rat: implications for an animal model of autism.
Topics: 1-Propanol; Acetic Acid; Aggression; Animals; Autistic Disorder; Brain; Disease Models, Animal; Ente | 2008 |
Synthesis of new imidazolyl acetic acid derivatives with anti-inflammatory and analgesic activities.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, A | 2008 |
Antiallergic effect of the root of Paeonia lactiflora and its constituents paeoniflorin and paeonol.
Topics: Acetic Acid; Acetophenones; Analgesics; Animals; Anti-Allergic Agents; Antipruritics; Asthma; Behavi | 2008 |
Increased susceptibility of annexin-A1 null mice to nociceptive pain is indicative of a spinal antinociceptive action of annexin-A1.
Topics: Acetic Acid; Analgesics; Animals; Annexin A1; Behavior, Animal; Dinoprostone; Disease Models, Animal | 2008 |
The antinociceptive effects of anticonvulsants in a mouse visceral pain model.
Topics: Acetic Acid; Amines; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Cyclohex | 2008 |
Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models.
Topics: Acetates; Acetic Acid; Animals; Ascitic Fluid; Cell Separation; Clostridium Infections; Colitis; Cri | 1984 |
Effect of fluoride on growth and acid production by Streptococcus mutans in dental plaque.
Topics: Acetates; Acetic Acid; Animals; Dental Plaque; Disease Models, Animal; Fluorides; Formates; Germ-Fre | 1984 |
Liver injury as a model of uncontrolled hemorrhagic shock: resuscitation with different hypertonic regimens.
Topics: Acetates; Acetic Acid; Animals; Disease Models, Animal; Hypertonic Solutions; Infusions, Intravenous | 1995 |
Healing-promoting action of the zinc-cimetidine complex on acetic acid-induced gastric ulcers in rats.
Topics: Acetates; Acetic Acid; Animals; Cimetidine; Disease Models, Animal; Dose-Response Relationship, Drug | 1995 |
Colitis and colonic mucosal barrier dysfunction.
Topics: Acetates; Acetic Acid; Animals; Carbon Radioisotopes; Cell Membrane Permeability; Colitis; Colon; Di | 1995 |
Isochloremic hypertonic solutions for severe hemorrhage.
Topics: Acetates; Acetic Acid; Animals; Blood Gas Analysis; Blood Proteins; Blood Volume; Chlorides; Dextran | 1993 |
Another model of acetic acid-induced colitis in the rat.
Topics: Acetates; Acetic Acid; Animals; Burns, Chemical; Colitis; Disease Models, Animal; Rats; Ulcer | 1994 |
IL-11, a pleiotropic cytokine: exciting new effects of IL-11 on gastrointestinal mucosal biology.
Topics: Acetates; Acetic Acid; Animals; Animals, Genetically Modified; beta 2-Microglobulin; Colitis; Cricet | 1994 |
The resistant hepatocyte model of carcinogenesis in the rat: the apparent independent development of oval cell proliferation and early nodules.
Topics: Acetates; Acetic Acid; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Bile Ducts; Blotting, We | 1995 |
Zinc deficiency delays gastric ulcer healing in rats.
Topics: Acetates; Acetic Acid; Animals; Bromodeoxyuridine; Cell Division; Diet; Disease Models, Animal; Gast | 1995 |
Effect of cimetidine and omeprazole on gastric ulcer healing of rats with limited food intake time.
Topics: Acetates; Acetic Acid; Administration, Oral; Analysis of Variance; Animals; Atropine; Cimetidine; Di | 1994 |
A device for automatic measurement of writhing and its application to the assessment of analgesic agents.
Topics: Acetates; Acetic Acid; Aminopyrine; Analgesics; Animals; Behavior, Animal; Caffeine; Disease Models, | 1994 |
Anti-nociceptive effects of aconiti tuber and its alkaloids.
Topics: Acetates; Acetic Acid; Aconitine; Analgesics; Animals; Arthritis, Experimental; Cold Temperature; Di | 1994 |
The leukocyte recruitment inhibitor, NPC 15669 accelerates healing in acetic acid-induced colitis.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Disease Mod | 1993 |
[Anti-ulcer effect of the drug OF-743 in an acid model of ulcer formation by the Okabe method].
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Disease Models, Animal; Gastric Mucosa; Male; Pep | 1993 |
Fibroblast growth factor in gastroprotection and ulcer healing: interaction with sucralfate.
Topics: Acetates; Acetic Acid; Acute Disease; Animals; Aspirin; Disease Models, Animal; Dose-Response Relati | 1993 |
Acetic acid-induced colitis results in bystander ileal injury.
Topics: Acetates; Acetic Acid; Animals; Body Fluids; Cecum; Colitis; Colon; Disease Models, Animal; Ileum; I | 1993 |
Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats.
Topics: Acetates; Acetic Acid; Analysis of Variance; Animals; Benzoquinones; Colitis; Colon; Cyclooxygenase | 1993 |
An experimental study of gastric stump carcinoma in Wistar rats.
Topics: Acetates; Acetic Acid; Adenocarcinoma; Animals; Disease Models, Animal; Gastric Stump; Male; Rats; R | 1995 |
Topical treatments for hydrofluoric acid dermal burns. Further assessment of efficacy using an experimental piq model.
Topics: Acetates; Acetic Acid; Administration, Topical; Animals; Antacids; Benzalkonium Compounds; Burns, Ch | 1996 |
Effects of an ethanolic extract of Desmodium adscendens on central nervous system in rodents.
Topics: Acetates; Acetic Acid; Analgesics; Analysis of Variance; Animals; Anticonvulsants; Body Temperature; | 1996 |
Experimental bilirubin pigmentation of rat dentine and its detection by a qualitative analytical method.
Topics: Acetic Acid; Animals; Bilirubin; Chloroform; Dentin; Disease Models, Animal; Female; Hyperbilirubine | 1996 |
Preliminary studies of analgesic and anti-inflammatory properties of Caesalpinia ferrea crude extract.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Carrageenan; Disease Models, Animal; Dose-Re | 1996 |
Exudative and absorptive permeability in different phases of an experimental colitis condition.
Topics: Acetic Acid; Animals; Cell Membrane Permeability; Chromium Radioisotopes; Colitis; Disease Models, A | 1996 |
Application of natural products in experimental models of intestinal inflammation in rats.
Topics: Acetic Acid; Alkaline Phosphatase; Animals; Biomarkers; Colitis; Disease Models, Animal; Humans; Inf | 1996 |
Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis.
Topics: Acetic Acid; Aminosalicylic Acids; Animals; Antioxidants; Butylated Hydroxytoluene; Colitis; Colitis | 1996 |
The prophylactic effects of superoxide dismutase, catalase, desferrioxamine, verapamil and disulfiram in experimental colitis.
Topics: Acetic Acid; Animals; Calcium Channel Blockers; Catalase; Colitis; Colonic Diseases; Deferoxamine; D | 1997 |
The anti-inflammatory effects of ketoprofen in animal experiments.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzenesulfonates; Bradykinin; Capill | 1997 |
Prevention of gastric ulcer relapse induced by indomethacin in rats by a mutein of basic fibroblast growth factor.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agen | 1997 |
Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats.
Topics: Acetic Acid; Animals; Collagenases; Connective Tissue; Disease Models, Animal; Gastric Mucosa; Gelat | 1997 |
Inoculation of VacA- and CagA- Helicobacter pylori delays gastric ulcer healing in the rat.
Topics: Acetic Acid; Animals; Antigens, Bacterial; Apoptosis; Bacterial Proteins; Cell Division; Disease Mod | 1997 |
Induction of plasma hepatocyte growth factor in acute colitis of mice.
Topics: Acetic Acid; Acute Disease; Administration, Rectal; Animals; Biomarkers; Colitis; Disease Models, An | 1997 |
Kinetics of fibroblasts in ulcer healing in rats: interference with indomethacin.
Topics: Acetic Acid; Actins; Animals; Apoptosis; Culture Techniques; Cyclooxygenase Inhibitors; Disease Mode | 1997 |
Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae).
Topics: Abdominal Pain; Acetic Acid; Animals; Bradykinin; Capsaicin; Disease Models, Animal; Dose-Response R | 1998 |
Anti-ulcer effects of antioxidants: effect of probucol.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Antioxidants; Chronic Disease; Cimetidine; D | 1998 |
[Effect of plaunotol on trinitrobenzene sulfonic acid and acetic acid induced colonic lesions in rats].
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Colon; Disease Models, Animal; Diterpenes; Dose-Response Re | 1998 |
Characterization of the analgesic and anti-inflammatory activities of ketorolac and its enantiomers in the rat.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Carrageenan; Cyclo | 1999 |
Effect of MEN 11467, a new tachykinin NK1 receptor antagonist, in acute rectocolitis induced by acetic acid in guinea-pigs.
Topics: Acetic Acid; Acute Disease; Administration, Rectal; Animals; Anti-Inflammatory Agents, Non-Steroidal | 1999 |
A new ulcer model, "unhealed gastric ulcers", induced by chronic treatment with indomethacin in rats with acetic acid ulcers.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cyclooxygenase Inh | 1999 |
Delayed healing of acetic-acid-induced gastric ulcer in portal hypertensive rats.
Topics: Acetic Acid; Animals; Cell Division; Disease Models, Animal; Gastric Mucosa; Hypertension, Portal; L | 1999 |
Antinociception produced by systemic, spinal and supraspinal administration of amiloride in mice.
Topics: Acetic Acid; Amiloride; Animals; Animals, Newborn; Behavior, Animal; Capsaicin; Disease Models, Anim | 1999 |
Antiinflammatory activity of adrenomedullin in the acetic acid peritonitis in rats.
Topics: Acetic Acid; Adrenomedullin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Relat | 1999 |
Distribution of Helicobacter pylori in a Mongolian gerbil gastric ulcer model.
Topics: Acetic Acid; Animals; Colony Count, Microbial; Disease Models, Animal; Gastric Mucosa; Gerbillinae; | 1999 |
Pharmacological screening of the aqueous extract of Musanga cecropiodes.
Topics: Acetic Acid; Analgesics; Animals; Disease Models, Animal; Female; Male; Mice; Muscle Contraction; Pl | 2000 |
The role of pH and osmolarity in evoking the acetic acid-induced wiping response in a model of nociception in frogs.
Topics: Acetic Acid; Animals; Behavior, Animal; Buffers; Disease Models, Animal; Epidermis; Formates; Hydroc | 2000 |
Stereotaxic delivery of corticosterone to the amygdala modulates colonic sensitivity in rats.
Topics: Acetic Acid; Amygdala; Animals; Anxiety; Behavior, Animal; Cholesterol; Colon; Colonic Diseases, Fun | 2001 |
Blood purine and energy status in rats with colitis.
Topics: Acetic Acid; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anim | 2001 |
Effect of oligofucose derivatives on acetic acid-induced gastric ulcer in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Male; | 2001 |
Expression of a specific mucin type recognized by monoclonal antibodies in the rat gastric mucosa regenerating from acetic acid-induced ulcer.
Topics: Acetic Acid; Animals; Antibodies, Monoclonal; Disease Models, Animal; Gastric Mucins; Gastric Mucosa | 2001 |
Expression of decorin and biglycan in rat gastric tissue: effects of ulceration and basic fibroblast growth factor.
Topics: Acetic Acid; Animals; Apoptosis; Biglycan; Decorin; Disease Models, Animal; Drug Evaluation, Preclin | 2001 |
Pressure immobilisation bandages in first-aid treatment of jellyfish envenomation: current recommendations reconsidered.
Topics: Acetic Acid; Animals; Australia; Bandages; Bites and Stings; Disease Models, Animal; Evidence-Based | 2001 |
B vitamins induce an antinociceptive effect in the acetic acid and formaldehyde models of nociception in mice.
Topics: Acetic Acid; Animals; Constriction; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; | 2001 |
Macrophage migration inhibitory factor is an important mediator in the pathogenesis of gastric inflammation in rats.
Topics: Acetic Acid; Acute Disease; Animals; Antibodies, Monoclonal; Disease Models, Animal; Gastritis; Gene | 2001 |
[The new experimental ulcerative colitis model in rats induced by subserosal injection of acetic acid].
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Disease Models, Animal; Inflamm | 2001 |
The involvement of the tetrodotoxin-resistant sodium channel Na(v)1.8 (PN3/SNS) in a rat model of visceral pain.
Topics: Acetic Acid; Administration, Intravesical; Animals; Disease Models, Animal; Female; Ganglia, Spinal; | 2001 |
Novel antioxidants zolimid and AEOL11201 ameliorate colitis in rats.
Topics: Acetic Acid; Amino Acids; Animals; Antioxidants; Colitis, Ulcerative; Colon; Disease Models, Animal; | 2001 |
FR167653, a potent suppressant of interleukin-1 and tumor necrosis factor-alpha production, ameliorates colonic lesions in experimentally induced acute colitis.
Topics: Acetic Acid; Acute Disease; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 2001 |
Involvement of vanilloid receptor VR1 and prostanoids in the acid-induced writhing responses of mice.
Topics: Acetic Acid; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; B | 2001 |
Adaptive cytoprotection against acetic acid induced colonic injury in rats.
Topics: Acetic Acid; Animals; Colon; Colonic Diseases; Culture Techniques; Cytoprotection; Disease Models, A | 2001 |
Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Chronic Disease; Cysteamine; Disease Models, | 2001 |
Prophylactic and curative effects of Bacopa monniera in gastric ulcer models.
Topics: Acetic Acid; Animals; Antioxidants; Aspirin; Catalase; Cell Division; Cold Temperature; Disease Mode | 2001 |
Experimental ulcers alter voltage-sensitive sodium currents in rat gastric sensory neurons.
Topics: Acetic Acid; Anesthetics, Local; Animals; Disease Models, Animal; Ganglia, Spinal; Gastritis; Hypera | 2002 |
[Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats].
Topics: Acetic Acid; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dino | 2001 |
Evaluation of the antinflammatory and analgesic activity of Sideritis canariensis var. pannosa in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Carrageenan; Chlo | 2002 |
Effects of ablation of N- and R-type Ca(2+) channels on pain transmission.
Topics: Acetic Acid; Animals; Behavior, Animal; Calcium Channels, N-Type; Calcium Channels, R-Type; Central | 2002 |
A comparative analysis of two models of colitis in rats.
Topics: Acetates; Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Ethanol; Intestinal Mucosa; | 1992 |
Mucosal protective activity of prostaglandin analogs in rodent colonic inflammation.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Colitis; Disease Models, Animal; Intestinal Mucos | 1992 |
Increased phospholipase A2 activity in peritoneal leukocytes in rat experimental colitis.
Topics: Acetates; Acetic Acid; Animals; Arthus Reaction; Colitis; Dexamethasone; Dinitrochlorobenzene; Disea | 1992 |
Ketotifen effectively prevents mucosal damage in experimental colitis.
Topics: Acetates; Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Intestinal Mucosa; Ketotifen | 1992 |
Acetic acid-induced colitis in the rat: a reproducible experimental model for acute ulcerative colitis.
Topics: Acetates; Acetic Acid; Animals; Castor Oil; Colitis, Ulcerative; Disease Models, Animal; Dose-Respon | 1992 |
Helicobacter pylori affects the quality of experimental gastric ulcer healing in a new animal model.
Topics: Acetates; Acetic Acid; Animals; Disease Models, Animal; Gastric Mucosa; Helicobacter pylori; Male; R | 1991 |
Evaluation of acetic acid-induced gastric ulcers in rats by scanning acoustic microscopy.
Topics: Acetates; Acetic Acid; Acoustics; Animals; Disease Models, Animal; Male; Microscopy; Rats; Rats, Inb | 1991 |
Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidi | 1991 |
Antiinflammatory effects of various drugs on acetic acid induced colitis in the rat.
Topics: Acetates; Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; | 1990 |
Toxicity of ototopical drugs: animal modeling.
Topics: Acetates; Acetic Acid; Action Potentials; Administration, Topical; Animals; Benzethonium; Chinchilla | 1990 |
[Experimental chronic stomach ulcer].
Topics: Acetates; Acetic Acid; Animals; Disease Models, Animal; Gastric Mucosa; Injections; Male; Rats; Rats | 1989 |
Continuous intravenous ammonia infusion as a model for the study of hepatic encephalopathy in rabbits.
Topics: Acetates; Acetic Acid; Ammonia; Animals; Blood Glucose; Disease Models, Animal; Electroencephalograp | 1989 |
[Lysosomal enzyme activity of the gastric mucosa in rats during experimental ulcer formation].
Topics: Acetates; Acetic Acid; Animals; Disease Models, Animal; Gastric Mucosa; Histamine; Lysosomes; Rats; | 1987 |
Metabolism of arachidonic acid in acetic acid colitis in rats. Similarity to human inflammatory bowel disease.
Topics: Acetates; Acetic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure L | 1985 |
Identification of experimentally induced colitis by in vitro nuclear magnetic resonance.
Topics: Acetates; Acetic Acid; Animals; Body Water; Colitis; Disease Models, Animal; In Vitro Techniques; In | 1985 |