acetic acid has been researched along with Colitis in 238 studies
Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It was aimed to induce a new experimental colitis model by using acetic acid and trinitrobenzene sulphonic acid together and to investigate the severity of inflammation biochemically and histopathologically in comparison with other models." | 8.31 | A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid. ( Astarcı, HM; Buğdaycı, G; Cinpolat, HY; Şengül, N, 2023) |
| "Fifty-six Wistar albino male rats were randomly divided into 4 groups as control, acetic acid, trinitrobenzene sulphonic acid, and combined groups, and the animals were sacrificed following the induction of colitis on the third day and on the seventh day." | 8.31 | A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid. ( Astarcı, HM; Buğdaycı, G; Cinpolat, HY; Şengül, N, 2023) |
| "The acetic acid model forms acute colitis." | 8.31 | A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid. ( Astarcı, HM; Buğdaycı, G; Cinpolat, HY; Şengül, N, 2023) |
| " The study used the acetic acid model of colitis and thereafter delayed the healing process by the administration of indomethacin (Indo) (2 mg/kg, SC)." | 8.31 | Neuroprotective effects of methyl jasmonate in male Wistar rats exposed to delayed acetic acid-induced ulcerative colitis: involvement of antioxidant status, GFAP, and IBA-1 immunoreactivities. ( Adedeji, TG; Aluko, OM; Ijomone, OM; Jeje, SO; Nathanniel, JN; Omayone, TP; Salami, FT, 2023) |
| " The objective of the present study is to elucidate for the first time the effects of Cotinus coggygria (CC) ethanol extract (CCE) on colonic structure and inflammation of acetic acid-induced ulcerative colitis in rats." | 8.31 | Cotinus coggygria Scop. Attenuates Acetic Acid-Induced Colitis in Rats by Regulation of Inflammatory Mediators. ( Akakın, D; Bitiş, L; Çevik, Ö; Ertaş, B; Kayalı, DG; Şen, A; Şener, G; Yıldırım, A, 2023) |
| " The oral administration of HA-BUD-ES-NPs in an acetic acid induced colitis rat model significantly mitigated the symptoms of IBD, and improved BUD therapeutic efficacy compared to drug suspension." | 8.31 | Targeted delivery of budesonide in acetic acid induced colitis: impact on miR-21 and E-cadherin expression. ( Allam, EA; El-Kamel, AH; El-Moslemany, RM; Elkafrawy, H; Seoudi, SS, 2023) |
| " This study evaluated the anti-inflammatory effects of licofelone on acetic acid-induced colitis in rats." | 8.31 | Licofelone Attenuates Acetic Acid-Induced Colitis in Rats Through Suppression of the Inflammatory Mediators. ( Abdolghaffari, AH; Abdollahi, AR; Baeeri, M; Dehpour, AR; Khayatan, D; Lashgari, NA; Momtaz, S; Roudsari, NM; Shahraki, FN, 2023) |
| "Sprague Dawley rats were treated with oral 500 mg/kg sulphasalazine or 30, 100, and 300 mg/kg of PNE daily for 8 days with induction of colitis on the fourth day with acetic acid." | 8.31 | Acetic acid-induced colitis modulating potential of total crude alkaloidal extract of Picralima nitida seeds in rats. ( Boakye-Gyasi, E; Okyere, PD; Oppong-Kyekyeku, J; Osafo, N; Otu-Boakye, SA; Yeboah, KO, 2023) |
| "Experimental ulcerative colitis was induced in rats by intrarectal acetic acid administration." | 8.31 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "This study shows the therapeutic potential of topotecan in attenuating ulcerative colitis in rats probably via inhibition of the RORγT transcription factor and downstream mediators of Th-17 cells." | 8.31 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "In this study, the therapeutic effect of quinic acid (QA), which has anti-inflammatory activity, was investigated on acetic acid-induced colitis in male Wistar rats." | 8.31 | Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways. ( Amini-Khoei, H; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M; Sabzevary-Ghahfarokhi, M, 2023) |
| "Ulcerative colitis (UC) was induced in rats by acetic acid intrarectally, and the protective effects of QA in 10, 30, 60, and 100 mg/kg doses were investigated." | 8.31 | Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways. ( Amini-Khoei, H; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M; Sabzevary-Ghahfarokhi, M, 2023) |
| "A total of twenty-four rats were divided into four groups (six animals in each group) as follows: (1) Control group; (2) acetic acid (AA)-induced colitis group (AA); (3) EMPA treatment group (AA + EMPA); (4) Dexamethasone (Dexa) treatment group (AA + Dexa)." | 8.31 | Biochemical and histopathological evidence for beneficial effects of Empagliflozin pretreatment on acetic acid-induced colitis in rats. ( Esmaeilzadeh, Z; Ghasemnejad-Berenji, M; Jafari, A; Nazari-Khanamiri, F, 2023) |
| "The current study was performed to evaluate the therapeutic impacts of the juglone in acetic acid-induced colitis in male Wistar rats." | 8.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| " Colitis was induced in 36 male Wistar rats (n = 6), except in the sham group, 1 ml of acetic acid 4% was administered intrarectally." | 8.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| " Juglone attenuated colitis symptoms, reduced inflammation cytokines, declined neutrophil infiltration, and suppressed IL- 1β and TNF-α expressions in acetic acid-induced colitis rats." | 8.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Juglone exhibited anti-inflammatory and antioxidant effects in the experimental colitis model and could be a therapeutic candidate for IBD." | 8.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Macroscopic and microscopic assessments revealed that juglone significantly decreased colonic tissue damage and inflammation at 150 mg/kg." | 8.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "IVM exerted promising anti-inflammatory effects in treating acetic acid-induced colitis in rats." | 8.12 | Anti-inflammatory Effects of Ivermectin in the Treatment of Acetic Acid-Induced Colitis in Rats: Involvement of GABA ( Aryannejad, A; Dehpour, AR; Iranshahi, S; Mashinchi, B; Mohammad Jafari, R; Noroozi, N; Rashidian, A; Tabary, M; Tavangar, SM, 2022) |
| "In this study, colitis was induced with intra-rectal injection of three concentrations of acetic acid (4, 6 and 8 v/v)." | 8.12 | Sodium Selenite Modulates IDO1/Kynurenine, TLR4, NF-κB and Bcl2/Bax Pathway and Mitigates Acetic Acid-Induced Colitis in Rat. ( Ala, M; Dehpour, AR; Jafari, RM; Nematian, H; Shadboorestan, A, 2022) |
| "These findings show that sodium selenite alleviates inflammatory response and oxidative stress and protects against colitis." | 8.12 | Sodium Selenite Modulates IDO1/Kynurenine, TLR4, NF-κB and Bcl2/Bax Pathway and Mitigates Acetic Acid-Induced Colitis in Rat. ( Ala, M; Dehpour, AR; Jafari, RM; Nematian, H; Shadboorestan, A, 2022) |
| "To investigate the effect of givinostat treatment in acetic acid-induced ulcerative colitis model in rats." | 8.12 | Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model. ( Dibekoğlu, C; Erbaş, O, 2022) |
| " Rats were randomly divided into three equal groups, and colitis was induced on 20 rats by rectal administration of %4 solutions of acetic acid." | 8.12 | Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model. ( Dibekoğlu, C; Erbaş, O, 2022) |
| "Givinostat, a good protector and regenerator of tissue and an anti-inflammatory agent, may be involved in the treatment of colitis in the future." | 8.12 | Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model. ( Dibekoğlu, C; Erbaş, O, 2022) |
| "Fifty rats were randomly separated into five groups (n = 10) with different durations (30 s, 5, 10, and 20 min) of exposure of the colon to 4% acetic acid and colitis was investigated for 0-9 days." | 8.12 | Improving Animal Model of Induced Colitis by Acetic Acid in Terms of Fibrosis and Inflammation Incidence in the Colon. ( Babaei, A; Bahrami, G; Madani, H; Malekshahi, H; Miraghaee, S, 2022) |
| "7 cells stimulated with LPS (1μg/mL) and in in-vivo study, colitis was induced by intra rectal administration of 4% Acetic acid." | 8.02 | Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats. ( S K, K; V S, A, 2021) |
| " Phloretin exerted ameliorative effect in both pre and post-treatment groups by restoring plasma ALP and LDH level and reduce inflammatory markers like myeloperoxidase, nitric oxide and eosinophil peroxidase level as well as downregulates colon ICAM-1 gene in acetic acid induced ulcerative colitis in rats." | 8.02 | Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats. ( S K, K; V S, A, 2021) |
| "Low dose vanadium proved beneficial in ameliorating acetic acid-induced colitis by improving both histopathological and haematological changes." | 8.02 | Biochemical and histopathological effects of low dose vanadium in the healing of acetic acid-induced colitis in male wistar rats. ( Olaleye, SB; Omayone, TP, 2021) |
| "Vanadium at small concentration functions as an essential trace element and may be able to promote healing process during ulcerative colitis." | 8.02 | Biochemical and histopathological effects of low dose vanadium in the healing of acetic acid-induced colitis in male wistar rats. ( Olaleye, SB; Omayone, TP, 2021) |
| " The purpose of this study is evaluating anti-inflammatory impacts of gabapentin on acetic acid-induced colitis in rats." | 8.02 | An investigation of the anti-inflammatory effects of gabapentin on acetic acid-induced colitis in rats. ( Bouzari, S; Dabirian, S; Karimian, P; Molavi, M; Motavallian, A; Torshkooh, FA; Zamani, E, 2021) |
| "The current study aimed to investigate the possible role of canagliflozin (CANA), a sodium-glucose co-transporter-2 inhibitor (SGLT-2), to prevent and treat acetic acid (AA)-induced colitis in a rat model." | 8.02 | Canagliflozin, an SGLT-2 inhibitor, ameliorates acetic acid-induced colitis in rats through targeting glucose metabolism and inhibiting NOX2. ( Bayoumi, AMA; Ibrahim, YF; Khalaf, HM; Khalifa, EMMA; Morsy, MA; Rifaai, RA, 2021) |
| "The goal of the current study was to evaluate the anti-inflammatory effect of Arthrocen against acetic acid-induced colitis in rats." | 7.96 | Arthrocen, an avocado-soy unsaponifiable agent, improves acetic acid-induced colitis in rat by inhibition of NF-kB signaling pathway. ( Abdollahi, A; Dehpour, A; Goudarzi, R; Mumtaz, F; Partoazar, A; Rashidian, A; Yousefi-Manesh, H, 2020) |
| "The phosphodiesterase-3 inhibitor, cilostazol has been recently shown to protect against chemically induced colitis in animal models." | 7.96 | Cilostazol protects against acetic acid-induced colitis in rats: Possible role for cAMP/SIRT1 pathway. ( Elhassanny, AEM; Elshazly, SM; Mahmoud, NM, 2020) |
| " An acetic acid-induced colitis model was produced in groups 2, 3 and 4 and was administered normal saline, topical GO and topical and systemic GO, respectively." | 7.96 | Effects of garlic oil (allium sativum) on acetic acid-induced colitis in rats: Garlic oil and experimental colitis. ( Can, M; Kılınç, F; Köktürk, F; Şen Tanrıkulu, C; Tanrıkulu, Y, 2020) |
| "GO can reduce colonic damage and inflammation in the acetic acid-induced colitis model, with effects on both local and systemic treatments, but with a more pronounced effect in local treatment." | 7.96 | Effects of garlic oil (allium sativum) on acetic acid-induced colitis in rats: Garlic oil and experimental colitis. ( Can, M; Kılınç, F; Köktürk, F; Şen Tanrıkulu, C; Tanrıkulu, Y, 2020) |
| "The aim of the present study is to investigate the protective effects of Foeniculum vulgare essential oil on intestinal inflammation through the inhibition of NF-kB pathway in acetic acid-induced rat colitis." | 7.88 | Foeniculum vulgare essential oil ameliorates acetic acid-induced colitis in rats through the inhibition of NF-kB pathway. ( Chamanara, M; Dehpour, AR; Motamed, SM; Rashidian, A; Rezayat, SM; Sahebgharani, M; Yazdanparast, M, 2018) |
| "Acute colitis was induced by intra-rectal administration of 2 mL of diluted acetic acid (4%) solution." | 7.88 | Foeniculum vulgare essential oil ameliorates acetic acid-induced colitis in rats through the inhibition of NF-kB pathway. ( Chamanara, M; Dehpour, AR; Motamed, SM; Rashidian, A; Rezayat, SM; Sahebgharani, M; Yazdanparast, M, 2018) |
| " vulgare essential oil on acetic acid-induced colitis in rats may involve the inhibition of NF-kB pathway." | 7.88 | Foeniculum vulgare essential oil ameliorates acetic acid-induced colitis in rats through the inhibition of NF-kB pathway. ( Chamanara, M; Dehpour, AR; Motamed, SM; Rashidian, A; Rezayat, SM; Sahebgharani, M; Yazdanparast, M, 2018) |
| "0 g kg-1) on intestinal immunity and microbiota in the acetic acid-induced colitis mouse model." | 7.88 | Effects of dietary tryptophan supplementation in the acetic acid-induced colitis mouse model. ( Bin, P; Chen, S; Liu, G; Ren, W; Tan, B; Wang, M; Xia, Y; Yang, H; Yin, L; Yin, Y, 2018) |
| " The aim of the present study was to examine whether administration of ghrelin affects the course of acetic acid-induced colitis and to determine what is the role of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) in this effect." | 7.85 | Essential Role of Growth Hormone and IGF-1 in Therapeutic Effect of Ghrelin in the Course of Acetic Acid-Induced Colitis. ( Ambroży, T; Bonior, J; Ceranowicz, D; Ceranowicz, P; Cieszkowski, J; Dembiński, A; Gil, K; Jaworek, J; Kuśnierz-Cabala, B; Olszanecki, R; Pihut, M; Warzecha, Z, 2017) |
| " In this study, we tested the hypothesis that carvacrol (CAR), a phenolic monoterpene with anti-inflammatory and antioxidant activities, can treat experimental colitis in mice." | 7.85 | Protective effect of carvacrol on acetic acid-induced colitis. ( Camargo, EA; Correa, CB; de Oliveira, JP; de Santana Souza, MT; Oliveira, AS; Quintans-Júnior, LJ; Teixeira, DF, 2017) |
| "The aims of the present study were to develop a colon-specific gel formulation of melatonin with sodium alginate and to evaluate its in vitro characteristics and intracolonic performance on oxidative stress parameters, such as nitric oxide (NOx), malondialdehyde (MDA) and glutathione (GSH) levels in rats with acetic acid-induced colitis." | 7.83 | Investigation of the effect of intracolonic melatonin gel formulation on acetic acid-induced colitis. ( Acartürk, F; Bircan, F; Coşkun Cevher, Ş; Esiringü, F; Sarı Kılıçaslan, SM; Tuğcu-Demiröz, F, 2016) |
| " This study investigates the ameliorative effect of Ocimum basilicum essential oil on an acetic acid-induced colitis model in rats." | 7.83 | Protective Effect of Ocimum basilicum Essential Oil Against Acetic Acid-Induced Colitis in Rats. ( Ghannadi, AR; Mehrzadi, S; Minaiyan, M; Rashidian, A; Roohi, P, 2016) |
| " The aim of present study was to determine the effect of obestatin administration on the course of acetic acid-induced colitis in rats." | 7.83 | Obestatin Accelerates the Healing of Acetic Acid-Induced Colitis in Rats. ( Ambroży, T; Bonior, J; Ceranowicz, P; Cieszkowski, J; Dembiński, A; Jaworek, J; Konturek, P; Kuśnierz-Cabala, B; Matuszyk, A; Warzecha, Z, 2016) |
| " In this study, we evaluated the ability of goat whey to prevent intestinal inflammation in the experimental model of acetic acid-induced rats and compared it to sulfasalazine." | 7.83 | Goat whey ameliorates intestinal inflammation on acetic acid-induced colitis in rats. ( Antonino de Assis, PO; Antunes de Araújo, A; Araújo, DFS; Formiga de Sousa, YR; Gálvez, J; Guerra, GCB; Júnior, RFA; Nunes de Medeiros, A; Pintado, MME; Queiroga, RCRDE, 2016) |
| " There is no study showing the efficacy of fostamatinib, with proven effects on some inflammatory diseases, on ulcerative colitis." | 7.81 | The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis. ( Aksit, H; Ayvaz, S; Can, G; Can, H; Demirtas, S; Karaca, T; Korkmaz, U; Kurt, M; Yilmaz, B, 2015) |
| "The study included 28 male Sprague-Dawley rats, randomly divided into control group, fostamatinib group, colitis group and fostamatinib + colitis group, each containing seven rats." | 7.81 | The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis. ( Aksit, H; Ayvaz, S; Can, G; Can, H; Demirtas, S; Karaca, T; Korkmaz, U; Kurt, M; Yilmaz, B, 2015) |
| "Fostamatinib reduced the inflammatory damage in the experimental colitis." | 7.81 | The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis. ( Aksit, H; Ayvaz, S; Can, G; Can, H; Demirtas, S; Karaca, T; Korkmaz, U; Kurt, M; Yilmaz, B, 2015) |
| " Present study is designed to evaluate the preventative activities of GS against acetic acid (AA)-induced ulcerative colitis in Wistar rats." | 7.80 | Pretreatment of Gymnema sylvestre revealed the protection against acetic acid-induced ulcerative colitis in rats. ( Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Aleisa, AM; Ola, MS; Parmar, MY, 2014) |
| " Colitis was induced by intracolonic instillation of 2 mL of 4% (v/v) acetic acid solution." | 7.80 | Protective effect of ginger volatile oil against acetic acid-induced colitis in rats: a light microscopic evaluation. ( Ghannadi, AR; Mahzooni, P; Mehrzadi, S; Minaiyan, M; Rashidian, A; Sadr, S, 2014) |
| "Acute colitis was induced by intrarectal administration of acetic acid." | 7.80 | The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid. ( Can, M; Dogan, Z; Ergul, B; Filik, L; Gonultas, MA; Hucumenoglu, S; Sarikaya, M, 2014) |
| " The aim of the present study was to investigate the potential protective effect of l-arginine (Arg; nitric oxide precursor) and aminoguanidine (inducible nitric oxide synthase inhibitor) against acetic acid (AA)-induced colitis in rats, and the potential role of NF-κB." | 7.80 | L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65. ( Farghaly, HS; Thabit, RH, 2014) |
| " The study aimed to elucidate the ameliorative effect of methanolic extract of Dillenia indica (DIME), hexane fraction (HFDI) and chloroform fraction (CFDI) of Dillenia indica in acetic acid induced experimental colitis in mice." | 7.80 | Protective effect of Dillenia indica L. on acetic acid induced colitis in mice. ( Badgujar, LB; Saraf, MN; Somani, SJ; Sutariya, BK, 2014) |
| "Thirty rats were divided into five groups: a control group, an acetic acid-induced colitis group, a group treated with melatonin before colitis induction, a group treated short-term after colitis induction, and a group treated long-term after colitis induction." | 7.79 | The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat. ( Blann, A; El Sers, DA; Idriss, NK; Jaumdally, RJ; Sayyed, HG, 2013) |
| "Melatonin is effective in prevention and short-term treatment of the inflammatory process in acetic-acid induced colitis whereas the benefit of long-term treatment is unclear." | 7.79 | The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat. ( Blann, A; El Sers, DA; Idriss, NK; Jaumdally, RJ; Sayyed, HG, 2013) |
| "Melatonin may be involved in gastrointestinal tract physiology and could affect inflammation-related gastrointestinal disorders." | 7.79 | The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat. ( Blann, A; El Sers, DA; Idriss, NK; Jaumdally, RJ; Sayyed, HG, 2013) |
| "Colonic tissue and plasma malondialdehyde levels were significantly lower in the iloprost administered colitis group than the colitis group (p<0." | 7.79 | Iloprost reduces colitis induced oxidative stress: An experimental study in rats. ( Aytaç, E; Göksel, S; Göksoy, E; Saygılı, S; Seymen, HO; Sözer, V; Teksöz, S; Tortum, OB; Uzun, H; Yavuz, N, 2013) |
| "Forty adult male Wistar-albino rats were randomly divided in to four equal weight-matched groups: sham group (n=10), iloprost administered sham group (n=10), colitis group (n=10), iloprost administered colitis group (n=10)." | 7.79 | Iloprost reduces colitis induced oxidative stress: An experimental study in rats. ( Aytaç, E; Göksel, S; Göksoy, E; Saygılı, S; Seymen, HO; Sözer, V; Teksöz, S; Tortum, OB; Uzun, H; Yavuz, N, 2013) |
| "We have demonstrated in this study iloprost to be an antioxidant, as well as iloprost demonstrating protective activity against colitis induced oxidative stress." | 7.79 | Iloprost reduces colitis induced oxidative stress: An experimental study in rats. ( Aytaç, E; Göksel, S; Göksoy, E; Saygılı, S; Seymen, HO; Sözer, V; Teksöz, S; Tortum, OB; Uzun, H; Yavuz, N, 2013) |
| "To evaluate the antioxidant effect of an extract of the plant Boswellia serrata in an experimental model of acute ulcerative colitis induced by administration of acetic acid (AA) in rats." | 7.78 | Effect of Boswellia serrata on antioxidant status in an experimental model of colitis rats induced by acetic acid. ( Fillmann, HS; Hartmann, RM; Marroni, NP; Morgan Martins, MI; Tieppo, J, 2012) |
| " Here, we examined the effects of THSG on experimental mice with colitis induced by acetic acid and whether the underlying mechanisms were associated with the PPAR-γ and NF-κB pathways." | 7.77 | Beneficial effects of THSG on acetic acid-induced experimental colitis: involvement of upregulation of PPAR-γ and inhibition of the Nf-Κb inflammatory pathway. ( Chang, MJ; Wang, JL; Xiao, JH; Zeng, C, 2011) |
| " This study aims to investigate granisetron, a 5-HT( 3) receptor antagonist, in acetic acid-induced rat colitis and probable involvement of 5-HT(3) receptors." | 7.76 | Granisetron ameliorates acetic acid-induced colitis in rats. ( Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mousavizadeh, K; Rahimian, R; Rasouli, MR, 2010) |
| " After induction of colitis, rats were treated with vehicle (dextran solution), mesalasine (120 mg/kg), budesonide suspension (300 microg/kg) and BSD-70 (equivalent to 300 microg/kg of budesonide), prednisolon (4 mg/kg), hydrocortisone acetate enema (20 mg/kg), and 5-ASA enema (Asacol) (400 mg/kg) for 5 days and then colon macroscopic and microscopic sections were examined for inflammatory response." | 7.76 | Effectiveness of budesonide-succinate-dextran conjugate as a novel prodrug of budesonide against acetic acid-induced colitis in rats. ( Ahmadi, F; Dorkoosh, F; Emami, J; Fassihi, A; Mahzouni, P; Minaiyan, M; Tavakoli, N; Varshosaz, J, 2010) |
| "This study investigated the effects of royal jelly (RJ) on acetic acid-induced colitis in rats." | 7.76 | Effect of royal jelly on experimental colitis Induced by acetic acid and alteration of mast cell distribution in the colon of rats. ( Bayiroglu, F; Comba, B; Karaca, T; Kaya, MS; Mis, L; Uslu, S; Yoruk, M, 2010) |
| "We investigated the effects of glutamine on markers of oxidative stress, nuclear factor kappaB (NF-kappaB) activation, and pro-inflammatory mediators in a rat model of experimental colitis induced by intracolonic administration of 7% acetic acid." | 7.74 | Glutamine inhibits over-expression of pro-inflammatory genes and down-regulates the nuclear factor kappaB pathway in an experimental model of colitis in the rat. ( Fillmann, H; González-Gallego, J; Kretzmann, NA; Llesuy, S; Marroni, N; San-Miguel, B; Tuñón, MJ, 2007) |
| "To investigate the effect and mechanism of epigallocatechin-3-gallate (EGCG) treatment in rats with acetic acid-induced colitis." | 7.74 | Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid. ( Chen, C; Ran, ZH; Xiao, SD, 2008) |
| "25g/kg/d, respectively, for 7 days using an established colitis model induced by 8% acetic acid." | 7.74 | Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid. ( Chen, C; Ran, ZH; Xiao, SD, 2008) |
| "Colitis was induced by intracolonic administration of acetic acid (5%) in Sprague-Dawley rats (200-250 g)." | 7.73 | Oxytocin ameliorates oxidative colonic inflammation by a neutrophil-dependent mechanism. ( Ercan, F; Gedik, N; Işeri, SO; Sağlam, B; Sener, G; Yeğen, BC, 2005) |
| "Experimental colitis induced by acetic acid has been used extensively as a model for intestinal inflammatory disease." | 7.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| "To assess the cytokine expression pattern identified through immunohistochemistry in colonic mucosa after experimental colitis induced by acetic acid and establish the relationship between this pattern and the presence of macroscopic lesions." | 7.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| "Adult male Wistar rats (n = 39) were divided at random into 4 groups: NC45 and NC24 (control without colitis; sacrificed at 45 minutes and 24 hours, respectively); and WC45 and WC24 (with experimental colitis induced by acetic acid; sacrificed at 45 minutes and 24 hours, respectively)." | 7.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| " Experimental colitis induced by acetic acid is a useful model for the development of studies assessing the role of cytokines in the inflammation of mucosa as well as anti-cytokine therapies." | 7.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| ", was investigated using a model of acetic acid-induced colitis in mice." | 7.73 | Protective effect of comaruman, a pectin of cinquefoil Comarum palustre L., on acetic acid-induced colitis in mice. ( Markov, PA; Nikitina, IR; Ovodov, YS; Ovodova, RG; Popov, SV, 2006) |
| " We aimed to investigate the antioxidant effect and the histopathologic changes caused by Gingko biloba on acetic acid-induced colitis." | 7.73 | The effects of Gingko biloba extract on acetic acid-induced colitis in rats. ( Aladağ, M; Ara, C; Demirel, U; Firat, S; Harputluoglu, MM; Hilmioğlu, F; Karadağ, N; Karincaoğlu, M; Temel, I; Yücel, N, 2006) |
| "Thus, a preventive effect of pectin from the common cranberry, namely oxycoccusan OP, on acetic acid-induced colitis in mice was detected." | 7.73 | Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice. ( Markov, PA; Nikitina, IR; Ovodov, YS; Petrishev, S; Popov, SV; Smirnov, V, 2006) |
| " Therefore, we assessed whether a series of desferrithiocin analogs, both carboxylic acids and hydroxamates, could (1) either promote or diminish the iron-mediated oxidation of ascorbate, (2) quench a model radical species, 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+), and (3) when applied topically, prevent acetic acid-induced colitis in rats." | 7.72 | Prevention of acetic acid-induced colitis by desferrithiocin analogs in a rat model. ( Bergeron, RJ; Nguyen, JN; Sninsky, CA; Weimar, WR; Wiegand, J, 2003) |
| " Indomethacin abolished the gross mucosal protective effect by 1% AA pretreatment in 8% AA-derived colitis in normal rats while the NS398 had no effect." | 7.72 | Acetic acid-derived prostaglandin-dependent colonic adaptive cytoprotection is preserved in chronic colitis: role of cyclo-oxygenase. ( Asama, T; Chisato, N; Kasai, S; Kono, T; Ohara, K; Yoneda, M, 2003) |
| "The present work was done to investigate the possible effects of thymoquinone on acetic acid-induced colitis in rats." | 7.72 | Thymoquinone protects against experimental colitis in rats. ( Mahgoub, AA, 2003) |
| " Leptin or CCK-8s was injected to rats intraperitoneally immediately before and 6 h after the induction of colitis with acetic acid." | 7.72 | Anti-inflammatory effects of leptin and cholecystokinin on acetic acid-induced colitis in rats: role of capsaicin-sensitive vagal afferent fibers. ( Bozkurt, A; Cakir, B; Ercan, F; Yeğen, BC, 2003) |
| "The present study was designed to compare the effect of leptin on acute colonic inflammation with that of acute stress exposure, which acts via the hypothalamic-pituitary-adrenal (HPA) axis." | 7.72 | The anti-inflammatory effect of leptin on experimental colitis: involvement of endogenous glucocorticoids. ( Bozkurt, A; Cakir, B; Ercan, F; Yeğen, BC, 2004) |
| "The oleo-resin from Copaifera langsdorffii (Leguminosae) was evaluated in rats on acetic acid-induced colitis." | 7.72 | Protective effect of Copaifera langsdorffii oleo-resin against acetic acid-induced colitis in rats. ( De Sousa, ET; Gurgel, LA; Paiva, LA; Rao, VS; Santos, FA; Silva, RM; Silveira, ER, 2004) |
| " We investigated the effects of an orally active NE inhibitor, ONO-6818, on acetic acid induced colitis in Syrian hamsters." | 7.72 | Effects of the neutrophil elastase inhibitor (ONO-6818) on acetic acid induced colitis in Syrian hamsters. ( Fujita, T; Hirota, Y; Katsube, N; Suzuki, M; Yamaguchi, K, 2004) |
| ", popularly known as 'aroeira' (AE), in the form of enemas prepared from the stem bark, on several morphologic and morphometric parameters after acetic acid-induced colitis in rats." | 7.71 | Morphologic and morphometric analyses of acetic acid-induced colitis in rats after treatment with enemas from Myracrodruon urundeuva Fr. All. (Aroeira do Sertão). ( Ferreira, FV; Matos, D; Regadas, FS; Rodrigues, LV; Viana, GS, 2002) |
| "Kaurenoic acid, a diterpene from Copaifera langsdorffii (Leguminaceae), was evaluated on rat colitis induced by acetic acid." | 7.71 | Anti-inflammatory effect of kaurenoic acid, a diterpene from Copaifera langsdorffi on acetic acid-induced colitis in rats. ( Gramosa, NV; Gurgel, LA; Paiva, LA; Rao, VS; Santos, FA; Silva, RM; Silveira, ER; Tomé, AR, 2002) |
| "Colitis reduces the blood and tissue levels of adenosine deaminase and adenylate deaminase." | 7.71 | Blood purine and energy status in rats with colitis. ( Al-Awadi, FM; Khan, I, 2001) |
| " Colitis was assessed 72 h after induction with acetic acid." | 7.71 | Effects of Lactobacillus rhamnosus GG and Lactobacillus reuteri R2LC on acetic acid-induced colitis in rats. ( Holma, R; Korpela, R; Lohi, J; Salmenperä, P; Vapaatalo, H, 2001) |
| "The rat strain Lactobacillus reuteri R2LC, but not the human strain Lactobacillus rhamnosus GG, is of benefit in reducing the severity of acetic acid-induced colitis in rats." | 7.71 | Effects of Lactobacillus rhamnosus GG and Lactobacillus reuteri R2LC on acetic acid-induced colitis in rats. ( Holma, R; Korpela, R; Lohi, J; Salmenperä, P; Vapaatalo, H, 2001) |
| "The aim of this study was to examine the efficacy of rebamipide on acetic acid-induced colitis in rats." | 7.70 | Protection by rebamipide against acetic acid-induced colitis in rats: relationship with its antioxidative activity. ( Osaka, T; Sakurai, K; Yamasaki, K, 1998) |
| "The anti-inflammatory effect of c-phycocyanin extract was studied in acetic acid-induced colitis in rats." | 7.70 | Anti-inflammatory activity of phycocyanin extract in acetic acid-induced colitis in rats. ( Ancheta, O; Armesto, J; González, A; González, R; Merino, N; Remirez, D; Rodríguez, S; Romay, C, 1999) |
| "To assess the possible involvement of mast cells and/or their mediators in inflammatory bowel diseases, the effect of the histamine H1 antagonist Dithiaden was studied on a model of acetic acid-induced colitis in rats." | 7.70 | Effects of histamine H1 antagonist dithiaden on acetic acid-induced colitis in rats. ( Nosál'ová, V; Ondrejicková, O; Pecivová, J, 1999) |
| " This study was conducted to compare the effect of D-002 and sulfasalazine on acetic acid-induced colitis in rats administered at 1, 5." | 7.70 | Comparative study of D-002 versus sulfasalazine on acetic acid-induced colitis in rats. ( Carbajal, D; Más, R; Molina, V; Noa, M; Valdés, S, 2000) |
| "(1) To verify the proposed role of reactive oxygen species (ROS) in ulcerative colitis, the effect of an antioxidant N-acetylcysteine (NAC) was studied in acetic acid (AA)-induced colonic inflammation." | 7.70 | Effect of N-acetylcysteine on colitis induced by acetic acid in rats. ( Bauer, V; Cerná, S; Nosál'ová, V, 2000) |
| " To investigate its effect on large intestinal mucosal injury, we used acetic acid-induced colitis in the rat." | 7.69 | Therapeutic effect of colloid bismuth subcitrate in experimental colitis in the rat. ( Burg, Z; Dinari, G; Karmeli, F; Marcus, H; Nusinovitz, M; Zahavi, I, 1995) |
| " The aim of this study was to examine the regulation of manganese superoxide dismutase (SOD) in acute acetic acid-induced colitis." | 7.69 | Induction and immunolocalization of manganese superoxide dismutase in acute acetic acid-induced colitis in the rat. ( Campbell-Thompson, M; Nick, HS; Stevenot, SA; Tannahill, CL; Valentine, JF, 1995) |
| "Colitis was induced in adult rats by the rectal administration of 5% acetic acid." | 7.69 | Induction and immunolocalization of manganese superoxide dismutase in acute acetic acid-induced colitis in the rat. ( Campbell-Thompson, M; Nick, HS; Stevenot, SA; Tannahill, CL; Valentine, JF, 1995) |
| "To study the effect of local or parenteral administration of the glucocorticoid budesonide in the acetic acid-induced colitis model in the rat." | 7.69 | Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat. ( Ar'Rajab, A; Brattsand, R; Erlansson, M; Fabia, R; Svensjö, E; Willén, R, 1994) |
| "Colitis was induced in an exteriorized colonic segment by administration of 4% acetic acid for 15 s." | 7.69 | Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat. ( Ar'Rajab, A; Brattsand, R; Erlansson, M; Fabia, R; Svensjö, E; Willén, R, 1994) |
| "75 mg/kg in the attenuation of acetic acid-induced colitis in the rat, but resulted in minor systemic side-effects." | 7.69 | Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat. ( Ar'Rajab, A; Brattsand, R; Erlansson, M; Fabia, R; Svensjö, E; Willén, R, 1994) |
| " rpS2 expression was also examined in the rectum during the course of acetic acid-induced colitis; rpS2 mRNA was detected during the acute phase of colitis but not in normal controls or during the recovery phase." | 7.69 | cDNA cloning of rat pS2 peptide and expression of trefoil peptides in acetic acid-induced colitis. ( Itoh, H; Kataoka, H; Kobayashi, T; Nawa, Y; Sekiya, R; Tomita, M; Uchino, H, 1996) |
| " The aim of the present study is to clarify the relative importance of mast cells in the progression of acetic acid-induced colitis in mice." | 7.69 | Evaluation of the role of mast cells in the progression of acetic acid-induced colitis in mice. ( Eto, T; Higa, A; Ishikawa, N; Nawa, Y, 1996) |
| "These results discount, but do not disprove, the role of mast cells in the progression of acetic acid-induced colitis in mice." | 7.69 | Evaluation of the role of mast cells in the progression of acetic acid-induced colitis in mice. ( Eto, T; Higa, A; Ishikawa, N; Nawa, Y, 1996) |
| " Pretreatment with a mast cell stabilizer, ketotifen, did not affect the severity of colitis in +/+ mice." | 7.69 | Evaluation of the role of mast cells in the progression of acetic acid-induced colitis in mice. ( Eto, T; Higa, A; Ishikawa, N; Nawa, Y, 1996) |
| "In our study we have tried to compare the prophylactic effects of superoxide dismutase (SOD), SOD+catalase (CAT), desferrioxamine, verapamil and disulfiram, which are all free oxygen radical (FOR) scavengers, in an animal model of experimental acetic acid colitis." | 7.69 | The prophylactic effects of superoxide dismutase, catalase, desferrioxamine, verapamil and disulfiram in experimental colitis. ( Cokneşelí, B; Köksoy, FN; Köse, H; Soybír, GR; Yalçin, O, 1997) |
| "In order to study the cytoprotective function of heat shock proteins (HSPs) in vivo, the effect of preinduction of HSPs by hyperthermia on acetic acid-induced colitis was investigated." | 7.69 | Effect of preinduction of heat shock proteins on acetic acid-induced colitis in rats. ( Itoh, H; Itoh, S; Iwabuchi, A; Jin, M; Masamune, O; Okuyama, A; Otaka, M; Otani, S; Sasahara, H; Tashima, Y, 1997) |
| "The present results, obtained using treatment with cyclophosphamide and ONO-4057, show that the severity or the progression of acetic acid-induced colitis in mice was not influenced by a reduction of circulating neutrophils to about 25% of base line." | 7.69 | Evaluation of the role of neutrophils in the pathogenesis of acetic acid-induced colitis in mice. ( Eto, T; Higa, A; Nawa, Y, 1997) |
| "The effect of the flavonoid rutoside on acetic acid-induced rat colitis was studied." | 7.69 | Rutoside as mucosal protective in acetic acid-induced rat colitis. ( Crespo, E; Cruz, T; Gálvez, J; Lorente, MD; Ocete, MA; Sánchez de Medina, F; Zarzuelo, A, 1997) |
| "The therapeutic efficacy of the leukocyte recruitment inhibitor, NPC 15669 (N-[9H-(2,7-dimethylfluoren-9-yl-methoxy)carbonyl]-L-leucine), was evaluated through the time course of acetic acid colitis in rats." | 7.68 | The leukocyte recruitment inhibitor, NPC 15669 accelerates healing in acetic acid-induced colitis. ( Lowe, VC; Noronha-Blob, L, 1993) |
| "The efficacy of the leukocyte recruitment inhibitor, N-[9H-2,7-dimethylfluoren-9-ylmethoxy)carbonyl]-L-leucine (NPC 15669) was compared with drugs used to treat inflammatory bowel diseases in a rat model, acetic acid-induced colitis." | 7.68 | NPC 15669, an inhibitor of neutrophil recruitment, is efficacious in acetic acid-induced colitis in rats. ( Burch, RM; Lowe, VC; Muhlhauser, RO; Noronha-Blob, L, 1993) |
| "The extent of the small intestinal injury following experimental acetic acid induction of colitis in rats was examined." | 7.68 | Acetic acid-induced colitis results in bystander ileal injury. ( Cui, N; Empey, LR; Fedorak, RN, 1993) |
| "The effects of ketotifen, a 'mast cell stabiliser,' on two models of experimental colitis were examined." | 7.68 | Ketotifen effectively prevents mucosal damage in experimental colitis. ( Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D, 1992) |
| " To more fully evaluate the role of arachidonic acid metabolites in the mediation of intestinal inflammation, we studied arachidonate metabolism in an animal model: acetic acid colitis in the rat." | 7.67 | Metabolism of arachidonic acid in acetic acid colitis in rats. Similarity to human inflammatory bowel disease. ( Sharon, P; Stenson, WF, 1985) |
| "Diffuse colitis was produced in rats by the intracolonic administration of 10% acetic acid." | 7.66 | Experimental colitis studied by colonoscopy in the rat: effect of indomethacin. ( Demers, LM; Mann, NS, 1983) |
| "Colitis was induced by intrarectal administration of 2 mL, 4% acetic acid." | 5.91 | Neuroprotective effects of methyl jasmonate in male Wistar rats exposed to delayed acetic acid-induced ulcerative colitis: involvement of antioxidant status, GFAP, and IBA-1 immunoreactivities. ( Adedeji, TG; Aluko, OM; Ijomone, OM; Jeje, SO; Nathanniel, JN; Omayone, TP; Salami, FT, 2023) |
| "Colitis was evoked by a single transrectal injection of 1 ml of 4 % acetic acid." | 5.91 | Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia activity. ( Ahmed, KA; Elbaz, EM; Essam, RM; Safwat, MH, 2023) |
| "Ulcerative colitis is characterized as a chronic immune-mediated inflammatory condition, affecting the intestinal gastroenteric tissue." | 5.91 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "Experimental ulcerative colitis was induced in rats by intrarectal acetic acid administration." | 5.91 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "Mirabegron's ability to increase adiponectin in serum and decrease glutathione, GSTM1, and catalase in the colon may account for its protective effects." | 5.91 | Mirabegron alleviates acetic acid-induced colitis in rats: Role of adiponectin and GSTM1/GSH detoxification pathway. ( Abed El Baky, MF; Hafez, HM; Mohamed, MZ; Mokhemer, SA, 2023) |
| "Mirabegron is a selective beta-3 adrenergic receptor (β-3 AR) agonist used to treat an overactive bladder." | 5.91 | Mirabegron alleviates acetic acid-induced colitis in rats: Role of adiponectin and GSTM1/GSH detoxification pathway. ( Abed El Baky, MF; Hafez, HM; Mohamed, MZ; Mokhemer, SA, 2023) |
| "Ulcerative colitis is a chronic inflammation of the colon." | 5.91 | Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue. ( Amini-Khoei, H; AnjomShoa, M; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2023) |
| "To induce ulcerative colitis, animals received 0." | 5.91 | Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue. ( Amini-Khoei, H; AnjomShoa, M; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2023) |
| "Empagliflozin (EMPA) is a sodium-glucose cotransporter-2 (SGLT2) inhibitor that has been shown to have anti-inflammatory and antioxidative effects." | 5.91 | Biochemical and histopathological evidence for beneficial effects of Empagliflozin pretreatment on acetic acid-induced colitis in rats. ( Esmaeilzadeh, Z; Ghasemnejad-Berenji, M; Jafari, A; Nazari-Khanamiri, F, 2023) |
| "All juglone-treated groups reduced the NF-κB levels compared to the control group (p < 0." | 5.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Juglone is a phenolic bioactive compound with antimicrobial, antitumour, antioxidant, and anti-inflammatory characteristics." | 5.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Juglone was extracted from Pterocarya fraxinifolia via maceration method." | 5.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Colitis was induced in 36 male Wistar rats (n = 6), except in the sham group, 1 ml of acetic acid 4% was administered intrarectally." | 5.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Treatment with taurine, Tau-CS-PT-NPs, and CS-PT-NPs partly reversed these effects." | 5.72 | Taurine loaded chitosan-pectin nanoparticle shows curative effect against acetic acid-induced colitis in rats. ( Abdel-Halim, M; Ahmed, O; Elamir, A; Farid, A, 2022) |
| "Ulcerative colitis is a chronic inflammatory disease, profoundly affecting the patient's quality of life and is associated with various complications." | 5.72 | Linagliptin ameliorates acetic acid-induced colitis via modulating AMPK/SIRT1/PGC-1α and JAK2/STAT3 signaling pathway in rats. ( El-Bahy, AAZ; El-Ghannam, MS; El-Yamany, MF; Nassar, NN; Saad, MA, 2022) |
| "Treatment with sodium selenite also significantly downregulated IL17, IL22, indoleamine 2,3-dioxygenase (IDO1), and kynurenine levels." | 5.72 | Sodium Selenite Modulates IDO1/Kynurenine, TLR4, NF-κB and Bcl2/Bax Pathway and Mitigates Acetic Acid-Induced Colitis in Rat. ( Ala, M; Dehpour, AR; Jafari, RM; Nematian, H; Shadboorestan, A, 2022) |
| "Colitis is a main presentation of inflammatory bowel disease (IBD) and yet, has no definitive cure." | 5.72 | Sodium Selenite Modulates IDO1/Kynurenine, TLR4, NF-κB and Bcl2/Bax Pathway and Mitigates Acetic Acid-Induced Colitis in Rat. ( Ala, M; Dehpour, AR; Jafari, RM; Nematian, H; Shadboorestan, A, 2022) |
| "The available ulcerative colitis drugs exhibit limited outcomes and adverse side effects." | 5.72 | Dual role of melatonin as an anti-colitis and anti-extra intestinal alterations against acetic acid-induced colitis model in rats. ( Ahmed, O; Elamir, A; Farid, A, 2022) |
| "Ulcerative colitis is an idiopathic disease that is widely incident worldwide." | 5.72 | Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis. ( Abdelhamid, AM; Amin, NA; Cavalu, S; El-Ahwany, E; El-Azez, RA; El-Rafi, AA; El-Sandarosy, R; Elagamy, HI; Essam, M; Essam, N; Gaafar, AGA; Girgis, S; Hasaballah, A; Kamal, I; Mahmoud, F; Mansour, M; Mohamed, D; Mohammed, OA; Nasr, M; Rizk, H; Saber, S; Youssef, ME, 2022) |
| "Phloretin (50 mg/kg) was given orally for 3 days to Wistar rats after induction for the post-treatment group and 1 day before induction to the pre-treatment group." | 5.62 | Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats. ( S K, K; V S, A, 2021) |
| "Vanadium has been reported to possess relevant therapeutic properties such as anti-diabetic and anti-tumoral." | 5.62 | Biochemical and histopathological effects of low dose vanadium in the healing of acetic acid-induced colitis in male wistar rats. ( Olaleye, SB; Omayone, TP, 2021) |
| "Colitis was thereafter induced by intra colonic administration of 1." | 5.62 | Biochemical and histopathological effects of low dose vanadium in the healing of acetic acid-induced colitis in male wistar rats. ( Olaleye, SB; Omayone, TP, 2021) |
| "Colitis was induced by the instillation of 2 mL of 3% acetic acid solution into rat's colons." | 5.62 | An investigation of the anti-inflammatory effects of gabapentin on acetic acid-induced colitis in rats. ( Bouzari, S; Dabirian, S; Karimian, P; Molavi, M; Motavallian, A; Torshkooh, FA; Zamani, E, 2021) |
| "Colitis was induced in male Wistar rats by intrarectal instillation of 1 ml of 4% (v/v) AA." | 5.62 | Canagliflozin, an SGLT-2 inhibitor, ameliorates acetic acid-induced colitis in rats through targeting glucose metabolism and inhibiting NOX2. ( Bayoumi, AMA; Ibrahim, YF; Khalaf, HM; Khalifa, EMMA; Morsy, MA; Rifaai, RA, 2021) |
| "Colitis was induced by intrarectal administration of acetic acid in all study groups except control group, and animals were treated by oral administration of dexamethasone and bupropion." | 5.56 | Bupropion Ameliorates Acetic Acid-Induced Colitis in Rat: the Involvement of the TLR4/NF-kB Signaling Pathway. ( Abdollahi, A; Chamanara, M; Dehpour, A; Dejban, P; Hasanvand, A; Karami Fard, K; Rashidian, A, 2020) |
| "Colitis was induced in rats by acetic acid and the rats were divided into four groups where one group served as experimental control and the other groups were treated with two doses of methanol extract of dried latex of C." | 5.51 | Protection afforded by methanol extract of Calotropis procera latex in experimental model of colitis is mediated through inhibition of oxidative stress and pro-inflammatory signaling. ( Das, P; Kumar, VL; Pandey, A; Verma, S, 2019) |
| "Pretreatment with zeaxanthin significantly reduced disease activity index, wet colon weight, ulcer area, macroscopic scores, and histological changes." | 5.51 | Zeaxanthin exerts protective effects on acetic acid-induced colitis in rats via modulation of pro-inflammatory cytokines and oxidative stress. ( El-Akabawy, G; El-Sherif, NM, 2019) |
| "Zeaxanthin is a nutritional carotenoid that belongs to the xanthophyll family of pigments." | 5.51 | Zeaxanthin exerts protective effects on acetic acid-induced colitis in rats via modulation of pro-inflammatory cytokines and oxidative stress. ( El-Akabawy, G; El-Sherif, NM, 2019) |
| "Ulcerative colitis is a common intestinal inflammatory disease characterized by upregulation of pro-inflammatory cytokines and oxidative stress." | 5.51 | Zeaxanthin exerts protective effects on acetic acid-induced colitis in rats via modulation of pro-inflammatory cytokines and oxidative stress. ( El-Akabawy, G; El-Sherif, NM, 2019) |
| "Acute colitis was induced by intra-rectal administration of 2 mL of diluted acetic acid (4%) solution." | 5.48 | Foeniculum vulgare essential oil ameliorates acetic acid-induced colitis in rats through the inhibition of NF-kB pathway. ( Chamanara, M; Dehpour, AR; Motamed, SM; Rashidian, A; Rezayat, SM; Sahebgharani, M; Yazdanparast, M, 2018) |
| "Colitis was induced with 3% (w/v) dextran sulfate sodium (DSS) in drinking water in mice for 1to7 days." | 5.48 | Betulinic acid alleviates dextran sulfate sodium-induced colitis and visceral pain in mice. ( Kalra, J; Kumar, D; Lingaraju, MC; Mathesh, K; Parida, S; Sharma, AK; Singh, TU; Tandan, SK, 2018) |
| "Colitis was induced by intrarectal instillation of 4% (v/v) acetic acid." | 5.48 | Sodium selenite ameliorates both intestinal and extra-intestinal changes in acetic acid-induced colitis in rats. ( Ainshoka, AA; Shouman, SA; Soliman, SM; Wadie, W, 2018) |
| "Ulcerative colitis is a chronic recurrent disease with incomplete treatment options." | 5.46 | The effect of sodium valproate on acetic acid-induced colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "Colitis was induced by intracolonic instillation of 2 mL of 3% acetic acid solution." | 5.46 | The effect of sodium valproate on acetic acid-induced colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "Colitis was induced by a rectal enema with 3." | 5.43 | Obestatin Accelerates the Healing of Acetic Acid-Induced Colitis in Rats. ( Ambroży, T; Bonior, J; Ceranowicz, P; Cieszkowski, J; Dembiński, A; Jaworek, J; Konturek, P; Kuśnierz-Cabala, B; Matuszyk, A; Warzecha, Z, 2016) |
| "Colitis was induced by intrarectal administration of 6% AA in BALB/c mice." | 5.43 | Flaxseed extract exhibits mucosal protective effect in acetic acid induced colitis in mice by modulating cytokines, antioxidant and antiinflammatory mechanisms. ( Gilani, AH; Iqbal, NT; Minhas, K; Palla, AH, 2016) |
| "Ulcerative colitis is a disease that causes inflammation and ulcer in the lining of the large intestine." | 5.40 | Protective effect of marine mangrove Rhizophora apiculata on acetic acid induced experimental colitis by regulating anti-oxidant enzymes, inflammatory mediators and nuclear factor-kappa B subunits. ( C, G; V, VP, 2014) |
| "Experimentally ulcerative colitis (UC) was induced by AA in animals pretreated with three different doses of GS leaves extract (50, 100, 200 mg/kg/day) and a single dose of mesalazine (MES, 300 mg/kg/day) for seven days." | 5.40 | Pretreatment of Gymnema sylvestre revealed the protection against acetic acid-induced ulcerative colitis in rats. ( Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Aleisa, AM; Ola, MS; Parmar, MY, 2014) |
| "Ulcerative colitis is a chronically recurrent inflammatory bowel disease of unknown origin." | 5.40 | Protective effect of ginger volatile oil against acetic acid-induced colitis in rats: a light microscopic evaluation. ( Ghannadi, AR; Mahzooni, P; Mehrzadi, S; Minaiyan, M; Rashidian, A; Sadr, S, 2014) |
| "Colitis was induced by intracolonic instillation of 2 mL of 4% (v/v) acetic acid solution." | 5.40 | Protective effect of ginger volatile oil against acetic acid-induced colitis in rats: a light microscopic evaluation. ( Ghannadi, AR; Mahzooni, P; Mehrzadi, S; Minaiyan, M; Rashidian, A; Sadr, S, 2014) |
| "Malondialdehyde levels were elevated in colitis group compared to other groups (p < 0." | 5.40 | The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid. ( Can, M; Dogan, Z; Ergul, B; Filik, L; Gonultas, MA; Hucumenoglu, S; Sarikaya, M, 2014) |
| "Ulcerative colitis is a chronic inflammatory condition of the colon, and reactive oxidative metabolites (ROMs) play an important role in its pathogenesis." | 5.40 | The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid. ( Can, M; Dogan, Z; Ergul, B; Filik, L; Gonultas, MA; Hucumenoglu, S; Sarikaya, M, 2014) |
| "Acute colitis was induced by intrarectal administration of acetic acid." | 5.40 | The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid. ( Can, M; Dogan, Z; Ergul, B; Filik, L; Gonultas, MA; Hucumenoglu, S; Sarikaya, M, 2014) |
| "Colitis was induced by intrarectal inoculation of rats with 4% acetic acid for three consecutive days." | 5.40 | L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65. ( Farghaly, HS; Thabit, RH, 2014) |
| "Ulcerative colitis is a chronic inflammatory disease and involves multiple etiological factors." | 5.39 | Protective effects of N-acetylcysteine on acetic acid-induced colitis in a porcine model. ( Chen, X; Ding, B; Hou, Y; Liu, Y; Long, M; Wang, L; Wang, Q; Wu, G; Yi, D, 2013) |
| "Quercetin (1) is an anti-inflammatory and antioxidant flavonoid." | 5.39 | Quercetin-loaded microcapsules ameliorate experimental colitis in mice by anti-inflammatory and antioxidant mechanisms. ( Baracat, MM; Casagrande, R; Colombo, BB; Fattori, V; Georgetti, SR; Guazelli, CF; Verri, WA; Vicentini, FT, 2013) |
| "Colitis was induced by acetic acid (AA)." | 5.38 | Nadroparin sodium activates Nrf2/HO-1 pathway in acetic acid-induced colitis in rats. ( Aygun, C; Bahcecioglu, IH; Demirel, U; Orhan, C; Ozercan, IH; Sahin, K; Tuzcu, M; Yalniz, M, 2012) |
| "Colitis was rendered by instillation of 1 mL of 4% acetic acid (vol/vol) and after 1 hour, granisetron (2 mg/kg), dexamethasone (1 mg/kg), meta-chlorophenylbiguanide (mCPBG, 5 mg/kg), a 5-HT( 3) receptor agonist, or granisetron + mCPBG was given intraperitoneally." | 5.36 | Granisetron ameliorates acetic acid-induced colitis in rats. ( Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mousavizadeh, K; Rahimian, R; Rasouli, MR, 2010) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid; the control group received physiological saline (10 mL kg(-1))." | 5.36 | Effect of royal jelly on experimental colitis Induced by acetic acid and alteration of mast cell distribution in the colon of rats. ( Bayiroglu, F; Comba, B; Karaca, T; Kaya, MS; Mis, L; Uslu, S; Yoruk, M, 2010) |
| "Colitis was induced by intracolonic (i." | 5.34 | Protective effect of melatonin in acetic acid induced colitis in rats. ( Cerná, S; Navarová, J; Nosál'ová, V; Zakálová, M; Zeman, M, 2007) |
| "Colitis was induced by intracolonic administration of acetic acid (5%) in Sprague-Dawley rats (200-250 g)." | 5.33 | Oxytocin ameliorates oxidative colonic inflammation by a neutrophil-dependent mechanism. ( Ercan, F; Gedik, N; Işeri, SO; Sağlam, B; Sener, G; Yeğen, BC, 2005) |
| "Acetic acid treatment caused haemorrhagic diarrhoea and weight loss in rats." | 5.33 | The effects of selective cyclooxygenase-2 inhibitors, celecoxib and rofecoxib, on experimental colitis induced by acetic acid in rats. ( Arafa, M; El-Medany, A; Mahgoub, A; Morsi, M; Mustafa, A, 2005) |
| "Ulcerative colitis is a chronic recurrent inflammatory bowel disease in which oxidative stress has been implicated." | 5.33 | Beneficial effects of N-acetylcysteine on acetic acid-induced colitis in rats. ( Bulbuloglu, E; Buyukbese, MA; Cetinkaya, A; Ciralik, H; Kantarceken, B; Kurutas, EB, 2005) |
| "Colitis was induced by intracolonic injection of 3% acetic acid." | 5.32 | Thymoquinone protects against experimental colitis in rats. ( Mahgoub, AA, 2003) |
| "Leptin or CCK-8s treatment reduced these parameters in a similar manner, while co-administration of leptin and CCK was found to be more effective in reducing the macroscopic score and WWI." | 5.32 | Anti-inflammatory effects of leptin and cholecystokinin on acetic acid-induced colitis in rats: role of capsaicin-sensitive vagal afferent fibers. ( Bozkurt, A; Cakir, B; Ercan, F; Yeğen, BC, 2003) |
| "Colitis was induced by intracolonic instillation of a 2 ml of 4% (v/v) acetic acid solution and 24 h later, the colonic mucosal damage was analyzed for the severity of macroscopic colonic damage, myeloperoxidase (MPO) activity, and malondialdehyde levels." | 5.32 | Protective effect of Copaifera langsdorffii oleo-resin against acetic acid-induced colitis in rats. ( De Sousa, ET; Gurgel, LA; Paiva, LA; Rao, VS; Santos, FA; Silva, RM; Silveira, ER, 2004) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid." | 5.32 | Electroacupuncture ameliorates experimental colitis induced by acetic acid in rat. ( Kang, JW; Kim, HJ; Kim, JY; Kim, TW; Kwon, YB; La, JH; Sung, TS; Yang, IS, 2004) |
| "Colitis was induced by intracolonic instillation of a 2 ml of 4% (v/v) acetic acid solution and, 24 h later, the colonic mucosal damage was analysed macroscopically for the severity of mucosal damage, the myeloperoxidase (MPO) activity and the malondialdehyde (MDA) levels in the colon segments." | 5.31 | Anti-inflammatory effect of kaurenoic acid, a diterpene from Copaifera langsdorffi on acetic acid-induced colitis in rats. ( Gramosa, NV; Gurgel, LA; Paiva, LA; Rao, VS; Santos, FA; Silva, RM; Silveira, ER; Tomé, AR, 2002) |
| "Colitis was induced by intrarectal administration of acetic acid and followed over a period of seven days." | 5.31 | Blood purine and energy status in rats with colitis. ( Al-Awadi, FM; Khan, I, 2001) |
| "Colitis was assessed 72 h after induction with acetic acid." | 5.31 | Effects of Lactobacillus rhamnosus GG and Lactobacillus reuteri R2LC on acetic acid-induced colitis in rats. ( Holma, R; Korpela, R; Lohi, J; Salmenperä, P; Vapaatalo, H, 2001) |
| "Colitis was induced in male Wistar/ST strain rats by intracolonic injection of 2 ml of 5% acetic acid." | 5.30 | Protection by rebamipide against acetic acid-induced colitis in rats: relationship with its antioxidative activity. ( Osaka, T; Sakurai, K; Yamasaki, K, 1998) |
| "Colitis was produced in male Wistar rats by rectal instillation of 5 and 10% acetic acid, following the methods of Eliakim et al." | 5.30 | Effect of dehydroleucodine in experimental colitis in rats and mice. ( Dominguez, S; Giordano, OS; Guerreiro, E; Guzman, JA; Maria, AO; Mohamed, F; Scardapane, L; Wendel, GH, 1999) |
| "Ketotifen pretreatment significantly decreased the macroscopic damage and the increase in colonic weight." | 5.29 | Ketotifen ameliorates capsaicin-augmented acetic acid-induced colitis. ( Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D, 1995) |
| "Colitis was induced two weeks later by flushing 2 ml 5% acetic acid into the proximal colon." | 5.29 | Ketotifen ameliorates capsaicin-augmented acetic acid-induced colitis. ( Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D, 1995) |
| "Colitis was produced in male Wistar rats by rectal instillation of 1 ml of 10% acetic acid followed immediately by 1." | 5.29 | Therapeutic effect of colloid bismuth subcitrate in experimental colitis in the rat. ( Burg, Z; Dinari, G; Karmeli, F; Marcus, H; Nusinovitz, M; Zahavi, I, 1995) |
| "Colitis was induced in adult rats by the rectal administration of 5% acetic acid." | 5.29 | Induction and immunolocalization of manganese superoxide dismutase in acute acetic acid-induced colitis in the rat. ( Campbell-Thompson, M; Nick, HS; Stevenot, SA; Tannahill, CL; Valentine, JF, 1995) |
| "03 mg/kg with 15% bioavailability on colonic application) was as effective as parenteral treatment at a dose of 0." | 5.29 | Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat. ( Ar'Rajab, A; Brattsand, R; Erlansson, M; Fabia, R; Svensjö, E; Willén, R, 1994) |
| "Colitis was induced in an exteriorized colonic segment by administration of 4% acetic acid for 15 s." | 5.29 | Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat. ( Ar'Rajab, A; Brattsand, R; Erlansson, M; Fabia, R; Svensjö, E; Willén, R, 1994) |
| "Acute colitis was induced in an isolated colonic segment by instillation of 4 per cent acetic acid for 15 s; this induces a uniform colitis after 4 days." | 5.29 | Effect of putative phospholipase A2 inhibitors on acetic acid-induced acute colitis in the rat. ( Andersson, R; Ar'Rajab, A; Bengmark, S; Fabia, R; Willén, R, 1993) |
| "Acetic acid colitis was induced 24 hr before enzyme inhibition began." | 5.29 | Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats. ( Guth, E; Guth, PH; LeDuc, LE; Reedy, T; Su, KC, 1993) |
| "Diffuse colitis was produced in rats by the intracolonic administration of 10% acetic acid." | 5.27 | Experimental colitis studied by colonoscopy in the rat: effect of indomethacin. ( Demers, LM; Mann, NS, 1983) |
| "Pirenzepine has been widely used for the treatment of gastric and duodenal ulcer." | 5.27 | Pirenzepine as anti-inflammatory drug in a model of experimental colitis in rat. ( Bustos-Fernández, L; Celener, D; González, E; Hamamura, S; Kofoed, JA; Ledesma de Paolo, MI; Schiffrin, E, 1987) |
| "It was aimed to induce a new experimental colitis model by using acetic acid and trinitrobenzene sulphonic acid together and to investigate the severity of inflammation biochemically and histopathologically in comparison with other models." | 4.31 | A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid. ( Astarcı, HM; Buğdaycı, G; Cinpolat, HY; Şengül, N, 2023) |
| "Fifty-six Wistar albino male rats were randomly divided into 4 groups as control, acetic acid, trinitrobenzene sulphonic acid, and combined groups, and the animals were sacrificed following the induction of colitis on the third day and on the seventh day." | 4.31 | A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid. ( Astarcı, HM; Buğdaycı, G; Cinpolat, HY; Şengül, N, 2023) |
| "The acetic acid model forms acute colitis." | 4.31 | A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid. ( Astarcı, HM; Buğdaycı, G; Cinpolat, HY; Şengül, N, 2023) |
| " The study used the acetic acid model of colitis and thereafter delayed the healing process by the administration of indomethacin (Indo) (2 mg/kg, SC)." | 4.31 | Neuroprotective effects of methyl jasmonate in male Wistar rats exposed to delayed acetic acid-induced ulcerative colitis: involvement of antioxidant status, GFAP, and IBA-1 immunoreactivities. ( Adedeji, TG; Aluko, OM; Ijomone, OM; Jeje, SO; Nathanniel, JN; Omayone, TP; Salami, FT, 2023) |
| " On the eighth day, Rats received enemas containing a 4 % solution of acetic acid to induce colitis." | 4.31 | Imatinib mitigates experimentally-induced ulcerative colitis: Possible contribution of NF-kB/JAK2/STAT3/COX2 signaling pathway. ( Abdelaziz, RR; Ghoneim, HA; Shalaby, M; Suddek, GM, 2023) |
| " The objective of the present study is to elucidate for the first time the effects of Cotinus coggygria (CC) ethanol extract (CCE) on colonic structure and inflammation of acetic acid-induced ulcerative colitis in rats." | 4.31 | Cotinus coggygria Scop. Attenuates Acetic Acid-Induced Colitis in Rats by Regulation of Inflammatory Mediators. ( Akakın, D; Bitiş, L; Çevik, Ö; Ertaş, B; Kayalı, DG; Şen, A; Şener, G; Yıldırım, A, 2023) |
| " The oral administration of HA-BUD-ES-NPs in an acetic acid induced colitis rat model significantly mitigated the symptoms of IBD, and improved BUD therapeutic efficacy compared to drug suspension." | 4.31 | Targeted delivery of budesonide in acetic acid induced colitis: impact on miR-21 and E-cadherin expression. ( Allam, EA; El-Kamel, AH; El-Moslemany, RM; Elkafrawy, H; Seoudi, SS, 2023) |
| " This study evaluated the anti-inflammatory effects of licofelone on acetic acid-induced colitis in rats." | 4.31 | Licofelone Attenuates Acetic Acid-Induced Colitis in Rats Through Suppression of the Inflammatory Mediators. ( Abdolghaffari, AH; Abdollahi, AR; Baeeri, M; Dehpour, AR; Khayatan, D; Lashgari, NA; Momtaz, S; Roudsari, NM; Shahraki, FN, 2023) |
| "Sprague Dawley rats were treated with oral 500 mg/kg sulphasalazine or 30, 100, and 300 mg/kg of PNE daily for 8 days with induction of colitis on the fourth day with acetic acid." | 4.31 | Acetic acid-induced colitis modulating potential of total crude alkaloidal extract of Picralima nitida seeds in rats. ( Boakye-Gyasi, E; Okyere, PD; Oppong-Kyekyeku, J; Osafo, N; Otu-Boakye, SA; Yeboah, KO, 2023) |
| "Experimental ulcerative colitis was induced in rats by intrarectal acetic acid administration." | 4.31 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "This study shows the therapeutic potential of topotecan in attenuating ulcerative colitis in rats probably via inhibition of the RORγT transcription factor and downstream mediators of Th-17 cells." | 4.31 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "In this study, the therapeutic effect of quinic acid (QA), which has anti-inflammatory activity, was investigated on acetic acid-induced colitis in male Wistar rats." | 4.31 | Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways. ( Amini-Khoei, H; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M; Sabzevary-Ghahfarokhi, M, 2023) |
| "Ulcerative colitis (UC) was induced in rats by acetic acid intrarectally, and the protective effects of QA in 10, 30, 60, and 100 mg/kg doses were investigated." | 4.31 | Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways. ( Amini-Khoei, H; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M; Sabzevary-Ghahfarokhi, M, 2023) |
| "The current study was performed to evaluate the therapeutic impacts of the juglone in acetic acid-induced colitis in male Wistar rats." | 4.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| " Colitis was induced in 36 male Wistar rats (n = 6), except in the sham group, 1 ml of acetic acid 4% was administered intrarectally." | 4.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| " Juglone attenuated colitis symptoms, reduced inflammation cytokines, declined neutrophil infiltration, and suppressed IL- 1β and TNF-α expressions in acetic acid-induced colitis rats." | 4.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Juglone exhibited anti-inflammatory and antioxidant effects in the experimental colitis model and could be a therapeutic candidate for IBD." | 4.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Macroscopic and microscopic assessments revealed that juglone significantly decreased colonic tissue damage and inflammation at 150 mg/kg." | 4.31 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "IVM exerted promising anti-inflammatory effects in treating acetic acid-induced colitis in rats." | 4.12 | Anti-inflammatory Effects of Ivermectin in the Treatment of Acetic Acid-Induced Colitis in Rats: Involvement of GABA ( Aryannejad, A; Dehpour, AR; Iranshahi, S; Mashinchi, B; Mohammad Jafari, R; Noroozi, N; Rashidian, A; Tabary, M; Tavangar, SM, 2022) |
| "To investigate the effect of givinostat treatment in acetic acid-induced ulcerative colitis model in rats." | 4.12 | Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model. ( Dibekoğlu, C; Erbaş, O, 2022) |
| " Rats were randomly divided into three equal groups, and colitis was induced on 20 rats by rectal administration of %4 solutions of acetic acid." | 4.12 | Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model. ( Dibekoğlu, C; Erbaş, O, 2022) |
| "Givinostat, a good protector and regenerator of tissue and an anti-inflammatory agent, may be involved in the treatment of colitis in the future." | 4.12 | Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model. ( Dibekoğlu, C; Erbaş, O, 2022) |
| "Due to the high side effects of commonly used drugs and according to the pharmacological properties reported for coumaric acid (CA), this study was designed to determine the impact of CA on acetic acid-induced colitis in rats, considering its possible anti-inflammatory, antioxidant, and anti-apoptotic properties." | 4.12 | Coumaric acid ameliorates experimental colitis in rats through attenuation of oxidative stress, inflammatory response and apoptosis. ( Amini-Khoei, H; Ashrafi-Dehkordi, K; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2022) |
| " Colitis was induced by acetic acid intrarectally." | 4.12 | Coumaric acid ameliorates experimental colitis in rats through attenuation of oxidative stress, inflammatory response and apoptosis. ( Amini-Khoei, H; Ashrafi-Dehkordi, K; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2022) |
| "Fifty rats were randomly separated into five groups (n = 10) with different durations (30 s, 5, 10, and 20 min) of exposure of the colon to 4% acetic acid and colitis was investigated for 0-9 days." | 4.12 | Improving Animal Model of Induced Colitis by Acetic Acid in Terms of Fibrosis and Inflammation Incidence in the Colon. ( Babaei, A; Bahrami, G; Madani, H; Malekshahi, H; Miraghaee, S, 2022) |
| "7 cells stimulated with LPS (1μg/mL) and in in-vivo study, colitis was induced by intra rectal administration of 4% Acetic acid." | 4.02 | Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats. ( S K, K; V S, A, 2021) |
| " Phloretin exerted ameliorative effect in both pre and post-treatment groups by restoring plasma ALP and LDH level and reduce inflammatory markers like myeloperoxidase, nitric oxide and eosinophil peroxidase level as well as downregulates colon ICAM-1 gene in acetic acid induced ulcerative colitis in rats." | 4.02 | Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats. ( S K, K; V S, A, 2021) |
| " The purpose of this study is evaluating anti-inflammatory impacts of gabapentin on acetic acid-induced colitis in rats." | 4.02 | An investigation of the anti-inflammatory effects of gabapentin on acetic acid-induced colitis in rats. ( Bouzari, S; Dabirian, S; Karimian, P; Molavi, M; Motavallian, A; Torshkooh, FA; Zamani, E, 2021) |
| "The current study aimed to investigate the possible role of canagliflozin (CANA), a sodium-glucose co-transporter-2 inhibitor (SGLT-2), to prevent and treat acetic acid (AA)-induced colitis in a rat model." | 4.02 | Canagliflozin, an SGLT-2 inhibitor, ameliorates acetic acid-induced colitis in rats through targeting glucose metabolism and inhibiting NOX2. ( Bayoumi, AMA; Ibrahim, YF; Khalaf, HM; Khalifa, EMMA; Morsy, MA; Rifaai, RA, 2021) |
| " The objective of this experiment is to investigate the protective effects of modafinil on colitis induced by acetic acid in rat and the involvement of nitric oxide pathway." | 3.96 | Biochemical and histopathological evidence for the beneficial effects of modafinil on the rat model of inflammatory bowel disease: involvement of nitric oxide pathway. ( Dehpour, AR; Dejban, P; Rahimi, N; Takzare, N, 2020) |
| "Colitis was induced by intra-rectal instillation of 1 ml acetic acid (4%)." | 3.96 | Biochemical and histopathological evidence for the beneficial effects of modafinil on the rat model of inflammatory bowel disease: involvement of nitric oxide pathway. ( Dehpour, AR; Dejban, P; Rahimi, N; Takzare, N, 2020) |
| "While induction of colitis caused severe macroscopic lesions, administration of dexamethasone and modafinil (100 and 150 mg/kg) significantly improved macroscopic ulcers." | 3.96 | Biochemical and histopathological evidence for the beneficial effects of modafinil on the rat model of inflammatory bowel disease: involvement of nitric oxide pathway. ( Dehpour, AR; Dejban, P; Rahimi, N; Takzare, N, 2020) |
| "The phosphodiesterase-3 inhibitor, cilostazol has been recently shown to protect against chemically induced colitis in animal models." | 3.96 | Cilostazol protects against acetic acid-induced colitis in rats: Possible role for cAMP/SIRT1 pathway. ( Elhassanny, AEM; Elshazly, SM; Mahmoud, NM, 2020) |
| " An acetic acid-induced colitis model was produced in groups 2, 3 and 4 and was administered normal saline, topical GO and topical and systemic GO, respectively." | 3.96 | Effects of garlic oil (allium sativum) on acetic acid-induced colitis in rats: Garlic oil and experimental colitis. ( Can, M; Kılınç, F; Köktürk, F; Şen Tanrıkulu, C; Tanrıkulu, Y, 2020) |
| "GO can reduce colonic damage and inflammation in the acetic acid-induced colitis model, with effects on both local and systemic treatments, but with a more pronounced effect in local treatment." | 3.96 | Effects of garlic oil (allium sativum) on acetic acid-induced colitis in rats: Garlic oil and experimental colitis. ( Can, M; Kılınç, F; Köktürk, F; Şen Tanrıkulu, C; Tanrıkulu, Y, 2020) |
| "The aim of the present study was to evaluate the anti-inflammatory effect of thymol in acetic acid-induced rat colitis through inhibiting the NF-κB signaling pathway." | 3.91 | Thymol reduces acetic acid-induced inflammatory response through inhibition of NF-kB signaling pathway in rat colon tissue. ( Abdollahi, A; Chamanara, M; Dehpour, A; Ghazi-Khansari, M; Nassireslami, E; Rashidian, A; Rezayat, SM, 2019) |
| "Colitis was induced by intra-rectal administration of 2 mL of diluted acetic acid (4%) solution using a flexible plastic rubber catheter in Wistar rats." | 3.91 | Thymol reduces acetic acid-induced inflammatory response through inhibition of NF-kB signaling pathway in rat colon tissue. ( Abdollahi, A; Chamanara, M; Dehpour, A; Ghazi-Khansari, M; Nassireslami, E; Rashidian, A; Rezayat, SM, 2019) |
| "The results of our study suggest that thymol exerts an anti-inflammatory effect in acetic acid-induced rat colitis by inhibiting the NF-κB signaling pathway and downregulating TNF-α and MPO expressions." | 3.91 | Thymol reduces acetic acid-induced inflammatory response through inhibition of NF-kB signaling pathway in rat colon tissue. ( Abdollahi, A; Chamanara, M; Dehpour, A; Ghazi-Khansari, M; Nassireslami, E; Rashidian, A; Rezayat, SM, 2019) |
| "The aims of the present study were to develop a colon-specific gel formulation of melatonin with sodium alginate and to evaluate its in vitro characteristics and intracolonic performance on oxidative stress parameters, such as nitric oxide (NOx), malondialdehyde (MDA) and glutathione (GSH) levels in rats with acetic acid-induced colitis." | 3.83 | Investigation of the effect of intracolonic melatonin gel formulation on acetic acid-induced colitis. ( Acartürk, F; Bircan, F; Coşkun Cevher, Ş; Esiringü, F; Sarı Kılıçaslan, SM; Tuğcu-Demiröz, F, 2016) |
| " This study investigates the ameliorative effect of Ocimum basilicum essential oil on an acetic acid-induced colitis model in rats." | 3.83 | Protective Effect of Ocimum basilicum Essential Oil Against Acetic Acid-Induced Colitis in Rats. ( Ghannadi, AR; Mehrzadi, S; Minaiyan, M; Rashidian, A; Roohi, P, 2016) |
| " The aim of present study was to determine the effect of obestatin administration on the course of acetic acid-induced colitis in rats." | 3.83 | Obestatin Accelerates the Healing of Acetic Acid-Induced Colitis in Rats. ( Ambroży, T; Bonior, J; Ceranowicz, P; Cieszkowski, J; Dembiński, A; Jaworek, J; Konturek, P; Kuśnierz-Cabala, B; Matuszyk, A; Warzecha, Z, 2016) |
| "This study aimed to evaluate potential protecting effect of ML and its major constituent, eucalyptol, against acetic acid-induced colitis in rats, a model of human inflammatory bowel disease (IBD)." | 3.83 | Mentha longifolia protects against acetic-acid induced colitis in rats. ( Abdallah, HM; Ali, SS; Murad, HA, 2016) |
| "Rats were divided into ten groups (n=8) given orally for three days (mg/kg/day) the following: normal control, acetic acid-induced colitis (un-treated, positive control), vehicle (DMSO), sulfasalazine (500), ML extract (100, 500, 1000), and eucalyptol (100, 200, 400)." | 3.83 | Mentha longifolia protects against acetic-acid induced colitis in rats. ( Abdallah, HM; Ali, SS; Murad, HA, 2016) |
| "ML (in moderate doses) and eucalyptol (dose-dependently) exerted protective effects against acetic acid-induced colitis in rats possibly through antioxidant and antiinflammatory properties suggesting a potential benefit in treatments of IBD." | 3.83 | Mentha longifolia protects against acetic-acid induced colitis in rats. ( Abdallah, HM; Ali, SS; Murad, HA, 2016) |
| " In this study, we evaluated the ability of goat whey to prevent intestinal inflammation in the experimental model of acetic acid-induced rats and compared it to sulfasalazine." | 3.83 | Goat whey ameliorates intestinal inflammation on acetic acid-induced colitis in rats. ( Antonino de Assis, PO; Antunes de Araújo, A; Araújo, DFS; Formiga de Sousa, YR; Gálvez, J; Guerra, GCB; Júnior, RFA; Nunes de Medeiros, A; Pintado, MME; Queiroga, RCRDE, 2016) |
| " The anti-inflammatory activity (on acetic acid-induced colitis in mice) of the initial polymer and its derivatives was studied." | 3.81 | Gelling polysaccharide from Chondrus armatus and its oligosaccharides: the structural peculiarities and anti-inflammatory activity. ( Anastyuk, SD; Barabanova, AO; Glazunov, VP; Kalitnik, AA; Marcov, PA; Ovodov, YS; Popov, SV; Yermak, IM, 2015) |
| " There is no study showing the efficacy of fostamatinib, with proven effects on some inflammatory diseases, on ulcerative colitis." | 3.81 | The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis. ( Aksit, H; Ayvaz, S; Can, G; Can, H; Demirtas, S; Karaca, T; Korkmaz, U; Kurt, M; Yilmaz, B, 2015) |
| "The study included 28 male Sprague-Dawley rats, randomly divided into control group, fostamatinib group, colitis group and fostamatinib + colitis group, each containing seven rats." | 3.81 | The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis. ( Aksit, H; Ayvaz, S; Can, G; Can, H; Demirtas, S; Karaca, T; Korkmaz, U; Kurt, M; Yilmaz, B, 2015) |
| "Fostamatinib reduced the inflammatory damage in the experimental colitis." | 3.81 | The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis. ( Aksit, H; Ayvaz, S; Can, G; Can, H; Demirtas, S; Karaca, T; Korkmaz, U; Kurt, M; Yilmaz, B, 2015) |
| "In order to demonstrate the possible protective effects of estrogen receptor (ER)-α and ERβ receptor subtypes in the pathogenesis of colonic and gastric oxidant damage, experimental ulcer and colitis were induced by acetic acid, and the animals were randomly divided as colitis, ulcer, and their corresponding non-ulcer and non-colitis control groups." | 3.80 | Estrogen alleviates acetic acid-induced gastric or colonic damage via both ERα- and ERβ-mediated and direct antioxidant mechanisms in rats. ( Ercan, F; Kumral, ZN; Memi, G; Yeğen, BC, 2014) |
| " The present study tested the hypothesis that dietary TBU supplementation could alleviate intestinal injury in the acetic acid (ACA)-induced porcine model of colitis." | 3.80 | Dietary supplementation with tributyrin alleviates intestinal injury in piglets challenged with intrarectal administration of acetic acid. ( Chen, X; Ding, B; Gong, J; Hou, Y; Liu, Y; Wang, L; Wang, Q; Wu, G; Yi, D; Yin, Y; Zhu, H, 2014) |
| " Present study is designed to evaluate the preventative activities of GS against acetic acid (AA)-induced ulcerative colitis in Wistar rats." | 3.80 | Pretreatment of Gymnema sylvestre revealed the protection against acetic acid-induced ulcerative colitis in rats. ( Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Aleisa, AM; Ola, MS; Parmar, MY, 2014) |
| " Inhibitory effect of nifedipine against cholinergic contractions, blunted in acetic acid-induced colitis, was also recovered in MC-treated rats." | 3.80 | Antispasmodic and myorelaxant effects of the flavoring agent methyl cinnamate in gut: potential inhibition of tyrosine kinase. ( Aragão, KS; Brito, TS; Cosker, F; Lahlou, S; Lima, FJ; Magalhães, PJ; Ribeiro-Filho, HV; Santos, AA; Silva, CM; Souza, MH, 2014) |
| "Acute colitis was induced by intrarectal administration of acetic acid." | 3.80 | The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid. ( Can, M; Dogan, Z; Ergul, B; Filik, L; Gonultas, MA; Hucumenoglu, S; Sarikaya, M, 2014) |
| " The aim of the present study was to investigate the potential protective effect of l-arginine (Arg; nitric oxide precursor) and aminoguanidine (inducible nitric oxide synthase inhibitor) against acetic acid (AA)-induced colitis in rats, and the potential role of NF-κB." | 3.80 | L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65. ( Farghaly, HS; Thabit, RH, 2014) |
| " We investigated the antinociceptive effect of botulinum toxin type A (BTX-A) in male Wistar rats in two models of visceral pain: peritonitis induced by intraperitoneal injection of 1% acetic acid and colitis induced by intracolonic instillation of 0." | 3.80 | Antinociceptive effect of botulinum toxin type A on experimental abdominal pain. ( Babić, A; Bach-Rojecky, L; Drinovac, V; Lacković, Z, 2014) |
| " This study aimed to evaluate the impact of the cholinergic anti-inflammatory pathway on the extent of tissue integrity, oxidant-antioxidant status and neutrophil infiltration to the inflamed organ in a rat model of acetic acid-induced colitis." | 3.79 | The role of cholinergic anti-inflammatory pathway in acetic acid-induced colonic inflammation in the rat. ( Alican, I; Ercan, F; Kolgazi, M; Uslu, U; Velioglu-Ogunc, A; Yuksel, M, 2013) |
| "Thirty rats were divided into five groups: a control group, an acetic acid-induced colitis group, a group treated with melatonin before colitis induction, a group treated short-term after colitis induction, and a group treated long-term after colitis induction." | 3.79 | The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat. ( Blann, A; El Sers, DA; Idriss, NK; Jaumdally, RJ; Sayyed, HG, 2013) |
| "Melatonin is effective in prevention and short-term treatment of the inflammatory process in acetic-acid induced colitis whereas the benefit of long-term treatment is unclear." | 3.79 | The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat. ( Blann, A; El Sers, DA; Idriss, NK; Jaumdally, RJ; Sayyed, HG, 2013) |
| "Melatonin may be involved in gastrointestinal tract physiology and could affect inflammation-related gastrointestinal disorders." | 3.79 | The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat. ( Blann, A; El Sers, DA; Idriss, NK; Jaumdally, RJ; Sayyed, HG, 2013) |
| "Colonic tissue and plasma malondialdehyde levels were significantly lower in the iloprost administered colitis group than the colitis group (p<0." | 3.79 | Iloprost reduces colitis induced oxidative stress: An experimental study in rats. ( Aytaç, E; Göksel, S; Göksoy, E; Saygılı, S; Seymen, HO; Sözer, V; Teksöz, S; Tortum, OB; Uzun, H; Yavuz, N, 2013) |
| "Forty adult male Wistar-albino rats were randomly divided in to four equal weight-matched groups: sham group (n=10), iloprost administered sham group (n=10), colitis group (n=10), iloprost administered colitis group (n=10)." | 3.79 | Iloprost reduces colitis induced oxidative stress: An experimental study in rats. ( Aytaç, E; Göksel, S; Göksoy, E; Saygılı, S; Seymen, HO; Sözer, V; Teksöz, S; Tortum, OB; Uzun, H; Yavuz, N, 2013) |
| "We have demonstrated in this study iloprost to be an antioxidant, as well as iloprost demonstrating protective activity against colitis induced oxidative stress." | 3.79 | Iloprost reduces colitis induced oxidative stress: An experimental study in rats. ( Aytaç, E; Göksel, S; Göksoy, E; Saygılı, S; Seymen, HO; Sözer, V; Teksöz, S; Tortum, OB; Uzun, H; Yavuz, N, 2013) |
| "To elucidate the ameliorative effect of hydroalcoholic extract of leaves of Hibiscus rosa sinensis (HRS) in acetic acid induced experimental colitis in male wistar rats." | 3.78 | Effect of hydroalcoholic extract of Hibiscus rosa sinensis Linn. leaves in experimental colitis in rats. ( Badole, SL; Bodhankar, SL; Ghosh, P; Ghule, AE; Gosavi, TP; Kandhare, AD; Raygude, KS, 2012) |
| "To evaluate the antioxidant effect of an extract of the plant Boswellia serrata in an experimental model of acute ulcerative colitis induced by administration of acetic acid (AA) in rats." | 3.78 | Effect of Boswellia serrata on antioxidant status in an experimental model of colitis rats induced by acetic acid. ( Fillmann, HS; Hartmann, RM; Marroni, NP; Morgan Martins, MI; Tieppo, J, 2012) |
| "In this study, we synthesized (±)-tylophorine malate (NK-007), an analog of tylophorine (DCB3503), and analyzed its anti-inflammatory effect in vivo using a dextran sulfate sodium (DSS)-induced colitis model and an acetic acid-induced colitis model." | 3.78 | A novel tylophorine analog NK-007 ameliorates colitis through inhibition of innate immune response. ( Bao, X; Chen, X; Han, L; Hong, Z; Hu, Y; Li, Y; Wang, K; Wang, P; Wang, Q; Wang, Z; Wen, T; Wu, M; Wu, Z; Yin, Z; Zhao, L; Zhou, X, 2012) |
| "Colitis was induced by intracolonic administration of acetic acid." | 3.77 | The effect of exopolysaccharide-producing probiotic strains on gut oxidative damage in experimental colitis. ( Aslım, B; Demirbağ, AE; Işık, S; Sengül, N; Uçar, G, 2011) |
| "Significant oxidative damage was associated with a higher level of malondialdehyde (MDA) activity and reduced antioxidant enzyme activities in the colitis model group." | 3.77 | The effect of exopolysaccharide-producing probiotic strains on gut oxidative damage in experimental colitis. ( Aslım, B; Demirbağ, AE; Işık, S; Sengül, N; Uçar, G, 2011) |
| " Acetic acid had no ameliorating effect on DSS-induced colitis compared to the control group." | 3.77 | Protective effects of Kurozu and Kurozu Moromimatsu on dextran sulfate sodium-induced experimental colitis. ( Fukuyama, N; Ishiwata, K; Mori, H; Nagano, M; Shizuma, T, 2011) |
| " Subsequently, its protective effect in indomethacin and iodoacetamide induced colitis in rats (45, 90, 180, 270 mg/kg) and acetic acid induced colitis in mice (65, 130, 250, 500 mg/kg) was assessed." | 3.77 | Protective effect of aqueous extract of Bombax malabaricum DC on experimental models of inflammatory bowel disease in rats and mice. ( Jagtap, AG; Niphadkar, PV; Phadke, AS, 2011) |
| " Body weight and bloody stool frequency were monitored as indices of severity of colitis after administration of dextran sulfate sodium, and at 12 days, all mice were sacrificed for examination of colonic pathology and nitrotyrosine production in the colon tissues." | 3.77 | Therapeutic effects of four molecular-weight fractions of Kurozu against dextran sulfate sodium-induced experimental colitis. ( Fujii, A; Fukuyama, N; Mori, H; Nagano, M; Shizuma, T, 2011) |
| " Here, we examined the effects of THSG on experimental mice with colitis induced by acetic acid and whether the underlying mechanisms were associated with the PPAR-γ and NF-κB pathways." | 3.77 | Beneficial effects of THSG on acetic acid-induced experimental colitis: involvement of upregulation of PPAR-γ and inhibition of the Nf-Κb inflammatory pathway. ( Chang, MJ; Wang, JL; Xiao, JH; Zeng, C, 2011) |
| " This study aims to investigate granisetron, a 5-HT( 3) receptor antagonist, in acetic acid-induced rat colitis and probable involvement of 5-HT(3) receptors." | 3.76 | Granisetron ameliorates acetic acid-induced colitis in rats. ( Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mousavizadeh, K; Rahimian, R; Rasouli, MR, 2010) |
| " After induction of colitis, rats were treated with vehicle (dextran solution), mesalasine (120 mg/kg), budesonide suspension (300 microg/kg) and BSD-70 (equivalent to 300 microg/kg of budesonide), prednisolon (4 mg/kg), hydrocortisone acetate enema (20 mg/kg), and 5-ASA enema (Asacol) (400 mg/kg) for 5 days and then colon macroscopic and microscopic sections were examined for inflammatory response." | 3.76 | Effectiveness of budesonide-succinate-dextran conjugate as a novel prodrug of budesonide against acetic acid-induced colitis in rats. ( Ahmadi, F; Dorkoosh, F; Emami, J; Fassihi, A; Mahzouni, P; Minaiyan, M; Tavakoli, N; Varshosaz, J, 2010) |
| " In vivo healing potential of KET-GLY was evaluated in acetic acid-induced experimental colitis model." | 3.75 | Optimized prodrug approach: a means for achieving enhanced anti-inflammatory potential in experimentally induced colitis. ( Dabas, S; Pathak, K; Philip, AK, 2009) |
| " This study aimed to investigate the possible protective effect of sildenafil citrate on the extent of tissue integrity, oxidant-antioxidant status and neutrophil infiltration to the inflamed organ in a rat model of acetic acid-induced colitis." | 3.75 | The effect of sildenafil, a phosphodiesterase-5 inhibitor, on acetic acid-induced colonic inflammation in the rat. ( Alican, I; Atukeren, P; Ercan, F; Ersoy, Y; Gumustas, K; Iseri, SO; Yuksel, M, 2009) |
| "Colitis was induced by intrarectal administration of 1 mL of 5% acetic acid to Sprague-Dawley rats (200-250 g; n = 7-8/group)." | 3.75 | The effect of sildenafil, a phosphodiesterase-5 inhibitor, on acetic acid-induced colonic inflammation in the rat. ( Alican, I; Atukeren, P; Ercan, F; Ersoy, Y; Gumustas, K; Iseri, SO; Yuksel, M, 2009) |
| "Sildenafil citrate administration to rats with acetic acid-induced colitis seems to be beneficial via prevention of lipid peroxidation, oxidant generation, cytokine production and neutrophil accumulation." | 3.75 | The effect of sildenafil, a phosphodiesterase-5 inhibitor, on acetic acid-induced colonic inflammation in the rat. ( Alican, I; Atukeren, P; Ercan, F; Ersoy, Y; Gumustas, K; Iseri, SO; Yuksel, M, 2009) |
| " Thalidomide is effective in reducing the extent of arthritis as well as reducing the seizure scoring and increasing seizure onset in the adjuvant arthritis group." | 3.74 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| "The present study was designed to compare the anti-inflammatory and antioxidant effects of two antidepressant drugs, desipramine [10,11-dihydro-5-[3-(methylamino) propyl]-5H-dibenz-[b,f]azepine monohydrochloride] and fluoxetine [N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propan-1-amine], administered with variable doses, on experimentally induced colitis in rats." | 3.74 | Do desipramine [10,11-dihydro-5-[3-(methylamino) propyl]-5H-dibenz[b,f]azepine monohydrochloride] and fluoxetine [N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propan-1-amine] ameliorate the extent of colonic damage induced by acetic acid in rats? ( Baraka, AM; El Din, NM; El Said Darwish, I; Guemei, AA, 2008) |
| "We investigated the effects of glutamine on markers of oxidative stress, nuclear factor kappaB (NF-kappaB) activation, and pro-inflammatory mediators in a rat model of experimental colitis induced by intracolonic administration of 7% acetic acid." | 3.74 | Glutamine inhibits over-expression of pro-inflammatory genes and down-regulates the nuclear factor kappaB pathway in an experimental model of colitis in the rat. ( Fillmann, H; González-Gallego, J; Kretzmann, NA; Llesuy, S; Marroni, N; San-Miguel, B; Tuñón, MJ, 2007) |
| " Therefore, we also evaluated the efficacy of acetate in murine models of inflammatory diseases, and found that acetate administration (as well as administration of dexamethasone) attenuated trinitrobenzenesulfonic acid-induced colitis and dinitrofluorobenzene-induced dermatitis." | 3.74 | Acetate inhibits NFAT activation in T cells via importin beta1 interference. ( Ando, T; Goto, H; Ishiguro, K; Maeda, O; Niwa, Y; Ohmiya, N, 2007) |
| " In this study, we examined the effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside (THSG), an active component extracted from Polygonum multiflorum Thunb, on acetic acid-induced acute colitis and mitomycin C-induced chronic colitis." | 3.74 | Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice. ( Chen, S; Han, T; Wang, J; Wang, X; Zhao, L, 2008) |
| "To investigate the effect and mechanism of epigallocatechin-3-gallate (EGCG) treatment in rats with acetic acid-induced colitis." | 3.74 | Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid. ( Chen, C; Ran, ZH; Xiao, SD, 2008) |
| "25g/kg/d, respectively, for 7 days using an established colitis model induced by 8% acetic acid." | 3.74 | Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid. ( Chen, C; Ran, ZH; Xiao, SD, 2008) |
| " In male Sprague-Dawley rats recovered from acetic acid-induced colitis, we monitored visceral nociceptive response by scoring the abdominal withdrawal reflex and simultaneously measuring the changes in arterial pulse rate." | 3.74 | Increased 5-hydroxytryptamine mediates post-inflammatory visceral hypersensitivity via the 5-hydroxytryptamine 3 receptor in rats. ( Choi, YD; Kim, HJ; Kim, TW; La, JH; Sung, TS; Yang, IS, 2008) |
| "IBS symptoms were produced in male Sprague-Dawley rats by inducing colitis with acetic acid." | 3.73 | Increase in neurokinin-1 receptor-mediated colonic motor response in a rat model of irritable bowel syndrome. ( Kim, HJ; Kim, JY; Kim, TW; La, JH; Sung, TS; Yang, IS, 2005) |
| "Colitis was induced by intracolonic administration of acetic acid (5%) in Sprague-Dawley rats (200-250 g)." | 3.73 | Oxytocin ameliorates oxidative colonic inflammation by a neutrophil-dependent mechanism. ( Ercan, F; Gedik, N; Işeri, SO; Sağlam, B; Sener, G; Yeğen, BC, 2005) |
| "All inflammation parameters were increased by acetic acid-induced colitis or ethanol-induced gastric ulcer compared with the control group." | 3.73 | Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes. ( Cevík, H; Ercan, F; Erkanli, G; Işman, CA; Yeğen, BC, 2005) |
| "Experimental colitis induced by acetic acid has been used extensively as a model for intestinal inflammatory disease." | 3.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| "To assess the cytokine expression pattern identified through immunohistochemistry in colonic mucosa after experimental colitis induced by acetic acid and establish the relationship between this pattern and the presence of macroscopic lesions." | 3.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| "Adult male Wistar rats (n = 39) were divided at random into 4 groups: NC45 and NC24 (control without colitis; sacrificed at 45 minutes and 24 hours, respectively); and WC45 and WC24 (with experimental colitis induced by acetic acid; sacrificed at 45 minutes and 24 hours, respectively)." | 3.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| " Experimental colitis induced by acetic acid is a useful model for the development of studies assessing the role of cytokines in the inflammation of mucosa as well as anti-cytokine therapies." | 3.73 | Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis. ( Alves, CC; Bertevello, PL; Campos, FM; Chiferi, V; Gama-Rodrigues, JJ; Logullo, AF; Nonogaki, S; Torrinhas, RS; Waitzberg, DL, 2005) |
| "Colitis was induced by intracolonic administration of acetic acid." | 3.73 | Effects of exopolysaccharide-producing probiotic strains on experimental colitis in rats. ( Aslím, B; Atalay, F; Bozkurt, H; Işik, S; Sakaoğullari, Z; Sengül, N; Uçar, G; Yücel, N, 2006) |
| " Chronic hypersensitivity was observed in rats following spontaneous resolution of trinitrobenzenesulfonic acid-induced colitis." | 3.73 | Activation of peripheral 5-HT receptors attenuates colonic sensitivity to intraluminal distension. ( Crowell, MD; Dennis, E; Greenwood-Van Meerveld, B; Hicks, G; Venkova, K, 2006) |
| " However, this observed alteration has not been reported with acetic acid-induced colitis." | 3.73 | Alteration of nitrergic neuromuscular transmission as a result of acute experimental colitis in rat. ( Kim, TW; La, JH; Sung, TS; Yang, IS, 2006) |
| ", was investigated using a model of acetic acid-induced colitis in mice." | 3.73 | Protective effect of comaruman, a pectin of cinquefoil Comarum palustre L., on acetic acid-induced colitis in mice. ( Markov, PA; Nikitina, IR; Ovodov, YS; Ovodova, RG; Popov, SV, 2006) |
| " We aimed to investigate the antioxidant effect and the histopathologic changes caused by Gingko biloba on acetic acid-induced colitis." | 3.73 | The effects of Gingko biloba extract on acetic acid-induced colitis in rats. ( Aladağ, M; Ara, C; Demirel, U; Firat, S; Harputluoglu, MM; Hilmioğlu, F; Karadağ, N; Karincaoğlu, M; Temel, I; Yücel, N, 2006) |
| "Thus, a preventive effect of pectin from the common cranberry, namely oxycoccusan OP, on acetic acid-induced colitis in mice was detected." | 3.73 | Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice. ( Markov, PA; Nikitina, IR; Ovodov, YS; Petrishev, S; Popov, SV; Smirnov, V, 2006) |
| " Therefore, we assessed whether a series of desferrithiocin analogs, both carboxylic acids and hydroxamates, could (1) either promote or diminish the iron-mediated oxidation of ascorbate, (2) quench a model radical species, 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+), and (3) when applied topically, prevent acetic acid-induced colitis in rats." | 3.72 | Prevention of acetic acid-induced colitis by desferrithiocin analogs in a rat model. ( Bergeron, RJ; Nguyen, JN; Sninsky, CA; Weimar, WR; Wiegand, J, 2003) |
| " Indomethacin abolished the gross mucosal protective effect by 1% AA pretreatment in 8% AA-derived colitis in normal rats while the NS398 had no effect." | 3.72 | Acetic acid-derived prostaglandin-dependent colonic adaptive cytoprotection is preserved in chronic colitis: role of cyclo-oxygenase. ( Asama, T; Chisato, N; Kasai, S; Kono, T; Ohara, K; Yoneda, M, 2003) |
| " In acetic acid-induced colitis in the rat, levels of malondialdehyde were found to be more markedly reduced with MED15 than with 5-aminosalicylic acid." | 3.72 | Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug. ( Belogi, L; Bettelli, E; Mezzadri, CM; Tubaro, E, 2003) |
| " In in vivo indomethacin-induced rat ileitis, MED15 heals better than 5-aminosalicylic acid and sulfasalazine, as well as down-regulating intestinal wall myeloperoxidase content." | 3.72 | Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug. ( Belogi, L; Bettelli, E; Mezzadri, CM; Tubaro, E, 2003) |
| "The present work was done to investigate the possible effects of thymoquinone on acetic acid-induced colitis in rats." | 3.72 | Thymoquinone protects against experimental colitis in rats. ( Mahgoub, AA, 2003) |
| " Leptin or CCK-8s was injected to rats intraperitoneally immediately before and 6 h after the induction of colitis with acetic acid." | 3.72 | Anti-inflammatory effects of leptin and cholecystokinin on acetic acid-induced colitis in rats: role of capsaicin-sensitive vagal afferent fibers. ( Bozkurt, A; Cakir, B; Ercan, F; Yeğen, BC, 2003) |
| "To investigate the ameliorative effects of sodium ferulate (SF) on acetic acid-induced colitis and their mechanisms in rats." | 3.72 | Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats. ( Dong, WG; Liu, SP; Luo, HS; Wu, DF; Yu, BP; Yu, JP, 2003) |
| "The colitis model of Sprague-Dawley rats was induced by intracolon enema with 8% (V/V) of acetic acid." | 3.72 | Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats. ( Dong, WG; Liu, SP; Luo, HS; Wu, DF; Yu, BP; Yu, JP, 2003) |
| "Administration of SF intracolonically may have significant therapeutic effects on the rat model of colitis induced by acetic acid enema, which was probably due to the mechanism of antioxidation, inhibition of arachidonic acid metabolism and NF-kappaB expression." | 3.72 | Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats. ( Dong, WG; Liu, SP; Luo, HS; Wu, DF; Yu, BP; Yu, JP, 2003) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid in male Sprague-Dawley rats." | 3.72 | Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis. ( Kang, JW; Kim, HJ; Kim, TW; La, JH; Sung, TS; Yang, IS, 2003) |
| "The present study was designed to compare the effect of leptin on acute colonic inflammation with that of acute stress exposure, which acts via the hypothalamic-pituitary-adrenal (HPA) axis." | 3.72 | The anti-inflammatory effect of leptin on experimental colitis: involvement of endogenous glucocorticoids. ( Bozkurt, A; Cakir, B; Ercan, F; Yeğen, BC, 2004) |
| " We investigated the effects of an orally active NE inhibitor, ONO-6818, on acetic acid induced colitis in Syrian hamsters." | 3.72 | Effects of the neutrophil elastase inhibitor (ONO-6818) on acetic acid induced colitis in Syrian hamsters. ( Fujita, T; Hirota, Y; Katsube, N; Suzuki, M; Yamaguchi, K, 2004) |
| " We aimed to re-evaluate the role of MMC in visceral hypersensitivity associated with IBS using a rat IBS model that develops the IBS symptom after a subsidence of acetic acid-induced colitis." | 3.72 | Role of mucosal mast cells in visceral hypersensitivity in a rat model of irritable bowel syndrome. ( Kim, HJ; Kim, JY; Kim, TW; La, JH; Sung, TS; Yang, IS, 2004) |
| ", popularly known as 'aroeira' (AE), in the form of enemas prepared from the stem bark, on several morphologic and morphometric parameters after acetic acid-induced colitis in rats." | 3.71 | Morphologic and morphometric analyses of acetic acid-induced colitis in rats after treatment with enemas from Myracrodruon urundeuva Fr. All. (Aroeira do Sertão). ( Ferreira, FV; Matos, D; Regadas, FS; Rodrigues, LV; Viana, GS, 2002) |
| "Kaurenoic acid, a diterpene from Copaifera langsdorffii (Leguminaceae), was evaluated on rat colitis induced by acetic acid." | 3.71 | Anti-inflammatory effect of kaurenoic acid, a diterpene from Copaifera langsdorffi on acetic acid-induced colitis in rats. ( Gramosa, NV; Gurgel, LA; Paiva, LA; Rao, VS; Santos, FA; Silva, RM; Silveira, ER; Tomé, AR, 2002) |
| "Colitis reduces the blood and tissue levels of adenosine deaminase and adenylate deaminase." | 3.71 | Blood purine and energy status in rats with colitis. ( Al-Awadi, FM; Khan, I, 2001) |
| " Colitis was assessed 72 h after induction with acetic acid." | 3.71 | Effects of Lactobacillus rhamnosus GG and Lactobacillus reuteri R2LC on acetic acid-induced colitis in rats. ( Holma, R; Korpela, R; Lohi, J; Salmenperä, P; Vapaatalo, H, 2001) |
| "The rat strain Lactobacillus reuteri R2LC, but not the human strain Lactobacillus rhamnosus GG, is of benefit in reducing the severity of acetic acid-induced colitis in rats." | 3.71 | Effects of Lactobacillus rhamnosus GG and Lactobacillus reuteri R2LC on acetic acid-induced colitis in rats. ( Holma, R; Korpela, R; Lohi, J; Salmenperä, P; Vapaatalo, H, 2001) |
| "Kinase assays, immunofluorescence imaging, and Western immunoblotting were performed on single circular smooth muscle cells obtained from the normal dog colon as well as from colon with experimental colitis induced by mucosal exposure to ethanol and acetic acid, to determine the distribution, expression, and activation of PKC isozymes." | 3.71 | Selective modulation of PKC isozymes by inflammation in canine colonic circular muscle cells. ( Ali, I; Sarna, SK, 2002) |
| "Male Sprague-Dawley rats having colitis induced by acetic acid or trinitrobenzenesulfonic acid (TNBS) were given injection of S-oligo (3 mg/kg, i." | 3.71 | Antisense inhibition of cyclooxygenase-2 causes a selective suppression of the Na+-H+ exchanger isoform 3 in rat kidney in experimental colitis. ( Khan, I, 2002) |
| "The aim of this study was to examine the efficacy of rebamipide on acetic acid-induced colitis in rats." | 3.70 | Protection by rebamipide against acetic acid-induced colitis in rats: relationship with its antioxidative activity. ( Osaka, T; Sakurai, K; Yamasaki, K, 1998) |
| "Colitis was induced by either flushing the colon with 2 ml 5% acetic acid or intracolonic administration of 30 mg trinitrobenzenesulphonic acid (TNB) dissolved in 0." | 3.70 | Hyperbaric oxygen: a novel modality to ameliorate experimental colitis. ( Better, OS; Karmeli, F; Okon, E; Rachmilewitz, D; Rubenstein, I, 1998) |
| "(1) HBO effectively decreases colitis induced by acetic acid and TNB." | 3.70 | Hyperbaric oxygen: a novel modality to ameliorate experimental colitis. ( Better, OS; Karmeli, F; Okon, E; Rachmilewitz, D; Rubenstein, I, 1998) |
| "Activation of neurons in the inferior mesenteric ganglion (IMG) was assessed using c-fos, JunB, and c-Jun expression in the guinea pig IMG and colonic myenteric plexus during mechanosensory stimulation and acute colitis in normal and capsaicin-treated animals." | 3.70 | Immediate-early gene expression in the inferior mesenteric ganglion and colonic myenteric plexus of the guinea pig. ( Keenan, CM; Parr, EJ; Sharkey, KA, 1999) |
| "The anti-inflammatory effect of c-phycocyanin extract was studied in acetic acid-induced colitis in rats." | 3.70 | Anti-inflammatory activity of phycocyanin extract in acetic acid-induced colitis in rats. ( Ancheta, O; Armesto, J; González, A; González, R; Merino, N; Remirez, D; Rodríguez, S; Romay, C, 1999) |
| "To assess the possible involvement of mast cells and/or their mediators in inflammatory bowel diseases, the effect of the histamine H1 antagonist Dithiaden was studied on a model of acetic acid-induced colitis in rats." | 3.70 | Effects of histamine H1 antagonist dithiaden on acetic acid-induced colitis in rats. ( Nosál'ová, V; Ondrejicková, O; Pecivová, J, 1999) |
| "To assess the possible role of reactive oxygen species in inflammatory bowel disease, the effect of the antioxidant and free radical scavenger stobadine was studied in acetic acid-induced experimental colitis." | 3.70 | Protective effect of stobadine in experimental colitis. ( Bauer, V; Nosál'ová, V, 1999) |
| " This study was conducted to compare the effect of D-002 and sulfasalazine on acetic acid-induced colitis in rats administered at 1, 5." | 3.70 | Comparative study of D-002 versus sulfasalazine on acetic acid-induced colitis in rats. ( Carbajal, D; Más, R; Molina, V; Noa, M; Valdés, S, 2000) |
| " During the course of acetic acid-induced experimental colitis in an in vivo mouse model, HAI-1 but not HAI-2 was upregulated in the recovery phase, suggesting that HAI-1 but not HAI-2 is associated with the regeneration of damaged colonic mucosa." | 3.70 | Upregulation of HGF activator inhibitor type 1 but not type 2 along with regeneration of intestinal mucosa. ( Hamasuna, R; Itoh, H; Kataoka, H; Kitamura, N; Koono, M; Nawa, Y; Tomita, M, 2000) |
| "(1) To verify the proposed role of reactive oxygen species (ROS) in ulcerative colitis, the effect of an antioxidant N-acetylcysteine (NAC) was studied in acetic acid (AA)-induced colonic inflammation." | 3.70 | Effect of N-acetylcysteine on colitis induced by acetic acid in rats. ( Bauer, V; Cerná, S; Nosál'ová, V, 2000) |
| " The mITF expression was up-regulated during the recovery phase after depletion of goblet cells in acetic acid-induced colitis." | 3.69 | Molecular cloning of mouse intestinal trefoil factor and its expression during goblet cell changes. ( Higa, A; Ide, H; Ishikawa, N; Itoh, H; Koga, Y; Maruyama, H; Murakumo, Y; Nawa, Y; Tomita, M, 1995) |
| " To investigate its effect on large intestinal mucosal injury, we used acetic acid-induced colitis in the rat." | 3.69 | Therapeutic effect of colloid bismuth subcitrate in experimental colitis in the rat. ( Burg, Z; Dinari, G; Karmeli, F; Marcus, H; Nusinovitz, M; Zahavi, I, 1995) |
| " The aim of this study was to examine the regulation of manganese superoxide dismutase (SOD) in acute acetic acid-induced colitis." | 3.69 | Induction and immunolocalization of manganese superoxide dismutase in acute acetic acid-induced colitis in the rat. ( Campbell-Thompson, M; Nick, HS; Stevenot, SA; Tannahill, CL; Valentine, JF, 1995) |
| "Colitis was induced in adult rats by the rectal administration of 5% acetic acid." | 3.69 | Induction and immunolocalization of manganese superoxide dismutase in acute acetic acid-induced colitis in the rat. ( Campbell-Thompson, M; Nick, HS; Stevenot, SA; Tannahill, CL; Valentine, JF, 1995) |
| "To study the effect of local or parenteral administration of the glucocorticoid budesonide in the acetic acid-induced colitis model in the rat." | 3.69 | Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat. ( Ar'Rajab, A; Brattsand, R; Erlansson, M; Fabia, R; Svensjö, E; Willén, R, 1994) |
| "Colitis was induced in an exteriorized colonic segment by administration of 4% acetic acid for 15 s." | 3.69 | Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat. ( Ar'Rajab, A; Brattsand, R; Erlansson, M; Fabia, R; Svensjö, E; Willén, R, 1994) |
| "75 mg/kg in the attenuation of acetic acid-induced colitis in the rat, but resulted in minor systemic side-effects." | 3.69 | Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat. ( Ar'Rajab, A; Brattsand, R; Erlansson, M; Fabia, R; Svensjö, E; Willén, R, 1994) |
| " To examine whether neutrophils play a role in the development of experimental colitides, the effects of a sustained neutropenia on multiple indices of colonic injury in rats was examined 24 hr following the initiation of colitis with the intrarectal application of acetic acid, trinitrobenzene sulfonic acid (TNBS)-ethanol, or the potent proinflammatory agent, phorbol-12-myristate-13-acetate (PMA)." | 3.69 | Neutrophil-independence of the initiation of colonic injury. Comparison of results from three models of experimental colitis in the rat. ( Berin, MC; Buell, MG, 1994) |
| " The aim of the present study is to clarify the relative importance of mast cells in the progression of acetic acid-induced colitis in mice." | 3.69 | Evaluation of the role of mast cells in the progression of acetic acid-induced colitis in mice. ( Eto, T; Higa, A; Ishikawa, N; Nawa, Y, 1996) |
| "These results discount, but do not disprove, the role of mast cells in the progression of acetic acid-induced colitis in mice." | 3.69 | Evaluation of the role of mast cells in the progression of acetic acid-induced colitis in mice. ( Eto, T; Higa, A; Ishikawa, N; Nawa, Y, 1996) |
| " Pretreatment with a mast cell stabilizer, ketotifen, did not affect the severity of colitis in +/+ mice." | 3.69 | Evaluation of the role of mast cells in the progression of acetic acid-induced colitis in mice. ( Eto, T; Higa, A; Ishikawa, N; Nawa, Y, 1996) |
| "Amplified chemiluminescence was used to measure reactive oxygen species production by colonic biopsy specimens from rats with acetic acid induced colitis and to assess the in vitro effect of conventional antioxidants, standard therapies and proposed novel therapies for inflammatory bowel disease." | 3.69 | Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis. ( Blades, S; Blake, DR; Chander, CL; Claxson, AW; Coumbe, A; Millar, AD; Morris, CJ; Panetta, J; Rampton, DS, 1996) |
| "The model was validated by demonstrating that the profile of effects on chemiluminescence of acetic acid induced colitis biopsy specimens given by conventional antioxidants (sodium azide, catalase, copper-zinc superoxide dismutase, dimethyl sulphoxide, N-acetylcysteine and ascorbate) and standard therapies (5-aminosalicylate and hydrocortisone) resembled that previously reported using biopsy specimens from ulcerative colitis." | 3.69 | Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis. ( Blades, S; Blake, DR; Chander, CL; Claxson, AW; Coumbe, A; Millar, AD; Morris, CJ; Panetta, J; Rampton, DS, 1996) |
| "The similarity of the chemiluminescence responses of colonic biopsy specimens from acetic acid induced colitis and ulcerative colitis to a range of conventional antioxidants and standard treatments suggests that this model is a useful method for testing the antioxidant potential of new therapies for inflammatory bowel disease." | 3.69 | Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis. ( Blades, S; Blake, DR; Chander, CL; Claxson, AW; Coumbe, A; Millar, AD; Morris, CJ; Panetta, J; Rampton, DS, 1996) |
| "In our study we have tried to compare the prophylactic effects of superoxide dismutase (SOD), SOD+catalase (CAT), desferrioxamine, verapamil and disulfiram, which are all free oxygen radical (FOR) scavengers, in an animal model of experimental acetic acid colitis." | 3.69 | The prophylactic effects of superoxide dismutase, catalase, desferrioxamine, verapamil and disulfiram in experimental colitis. ( Cokneşelí, B; Köksoy, FN; Köse, H; Soybír, GR; Yalçin, O, 1997) |
| "To investigate the profile of IL-1 beta mRNA in the colonic muscle of rats with acetic acid induced colitis." | 3.69 | Colonic muscle enhances the production of interleukin-1 beta messenger RNA in experimental colitis. ( al-Awadi, FM; Khan, I, 1997) |
| "Colitis was induced by intrarectal administration of 1 ml of 4% acetic acid 8 cm from anal margin." | 3.69 | Colonic muscle enhances the production of interleukin-1 beta messenger RNA in experimental colitis. ( al-Awadi, FM; Khan, I, 1997) |
| "The present results, obtained using treatment with cyclophosphamide and ONO-4057, show that the severity or the progression of acetic acid-induced colitis in mice was not influenced by a reduction of circulating neutrophils to about 25% of base line." | 3.69 | Evaluation of the role of neutrophils in the pathogenesis of acetic acid-induced colitis in mice. ( Eto, T; Higa, A; Nawa, Y, 1997) |
| "The effect of the flavonoid rutoside on acetic acid-induced rat colitis was studied." | 3.69 | Rutoside as mucosal protective in acetic acid-induced rat colitis. ( Crespo, E; Cruz, T; Gálvez, J; Lorente, MD; Ocete, MA; Sánchez de Medina, F; Zarzuelo, A, 1997) |
| "We examined the effects of a human milk diet on rats with chemical colitis induced with a 4% acetic acid enema." | 3.69 | Antiinflammatory effects of human milk on chemically induced colitis in rats. ( Alling, DW; Bishop, PR; Buescher, ES; Grazioso, CF; Werner, AL, 1997) |
| "Changes in the colonic mucosa-associated microflora were determined both in patients with active and inactive ulcerative colitis and in rats with acetic acid-induced colitis." | 3.68 | Impairment of bacterial flora in human ulcerative colitis and experimental colitis in the rat. ( Andersson, R; Ar'Rajab, A; Bengmark, S; Fabia, R; Jeppsson, B; Johansson, ML; Molin, G; Willén, R, 1993) |
| "The therapeutic efficacy of the leukocyte recruitment inhibitor, NPC 15669 (N-[9H-(2,7-dimethylfluoren-9-yl-methoxy)carbonyl]-L-leucine), was evaluated through the time course of acetic acid colitis in rats." | 3.68 | The leukocyte recruitment inhibitor, NPC 15669 accelerates healing in acetic acid-induced colitis. ( Lowe, VC; Noronha-Blob, L, 1993) |
| "The effect of octreotide, a synthetic analogue of somatostatin, on the modulation of the acetic acid model of experimental colitis was examined." | 3.68 | Octreotide effectively decreases mucosal damage in experimental colitis. ( Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D, 1993) |
| "The efficacy of the leukocyte recruitment inhibitor, N-[9H-2,7-dimethylfluoren-9-ylmethoxy)carbonyl]-L-leucine (NPC 15669) was compared with drugs used to treat inflammatory bowel diseases in a rat model, acetic acid-induced colitis." | 3.68 | NPC 15669, an inhibitor of neutrophil recruitment, is efficacious in acetic acid-induced colitis in rats. ( Burch, RM; Lowe, VC; Muhlhauser, RO; Noronha-Blob, L, 1993) |
| "The extent of the small intestinal injury following experimental acetic acid induction of colitis in rats was examined." | 3.68 | Acetic acid-induced colitis results in bystander ileal injury. ( Cui, N; Empey, LR; Fedorak, RN, 1993) |
| "Distal colitis was induced by intrarectal administration of trinitrobenzene sulfonic, acetic acid, or Trichinella spiralis larvae, or by intraperitoneal injection of mitomycin C." | 3.68 | On the specificity of altered muscle function in experimental colitis in rats. ( Collins, SM; Grossi, L; McHugh, K, 1993) |
| "We measured daily food intake and body weight in rats before and after the induction of colitis by intrarectal administration of either 2,4,6-trinitrobenzenesulfonic acid in ethyl alcohol (TNBE) or 4% acetic acid (AA)." | 3.68 | On the suppression of food intake in experimental models of colitis in the rat. ( Collins, SM; Keenan, C; McHugh, KJ; Wallace, JL; Weingarten, HP, 1993) |
| "The therapeutic effects of exogenous phosphatidylcholine and phosphatidylinositol on acetic acid-induced colitis in rats were evaluated." | 3.68 | Effects of phosphatidylcholine and phosphatidylinositol on acetic-acid-induced colitis in the rat. ( Ahrén, B; Andersson, R; Ar'Rajab, A; Bengmark, S; Fabia, R; Larsson, K; Willén, R, 1992) |
| "Two models of colitis produced in rats that have received significant attention over the past few years are the acetic acid and trinitrobenzene sulfonic acid (TNBS) models." | 3.68 | A comparative analysis of two models of colitis in rats. ( Grisham, MB; Marshall, S; Specian, RD; Yamada, Y, 1992) |
| "The mucosal protective prostaglandin analogs misoprostol, enisoprost, and SC-46275 (the 17E-18-cyclopentenyl analog of enisoprost) were tested in mouse and rat colitis induced by the intrarectal instillation of dilute acetic acid." | 3.68 | Mucosal protective activity of prostaglandin analogs in rodent colonic inflammation. ( Anglin, CP; Collins, PW; Fretland, DJ; Gasiecki, AF; Levin, S; Walsh, RE; Widomski, DL, 1992) |
| " We measured PLA2 activity in the peritoneal leukocytes and eicosanoid content in the peritoneal cavity of rats with experimental colitis induced by dinitrochlorobenzene, immune complex-mediated colitis, and acetic acid-induced colitis." | 3.68 | Increased phospholipase A2 activity in peritoneal leukocytes in rat experimental colitis. ( Biondi, RJ; Murthy, SN, 1992) |
| "The effects of ketotifen, a 'mast cell stabiliser,' on two models of experimental colitis were examined." | 3.68 | Ketotifen effectively prevents mucosal damage in experimental colitis. ( Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D, 1992) |
| " Myeloperoxidase activity was assayed in two animal models of inflammation: acetic acid-induced colitis in rats and Clostridium difficile enterotoxin-induced enteritis in hamsters." | 3.67 | Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. ( Krawisz, JE; Sharon, P; Stenson, WF, 1984) |
| " To investigate the metabolic fate of one of these low molecular weight proinflammatory peptides, N-formyl L-methionine L-leucine 125I-L-tyrosine was introduced into colon loops of healthy rats (n = 10) and rats with experimental colitis (n = 15) induced by rectal instillation of 15% (vol/vol) acetic acid." | 3.67 | Enterohepatic circulation of bacterial chemotactic peptide in rats with experimental colitis. ( Broom, MF; Butt, TJ; Chadwick, VS; Ferry, DM; Hobson, CH; Hunter, J, 1988) |
| " To more fully evaluate the role of arachidonic acid metabolites in the mediation of intestinal inflammation, we studied arachidonate metabolism in an animal model: acetic acid colitis in the rat." | 3.67 | Metabolism of arachidonic acid in acetic acid colitis in rats. Similarity to human inflammatory bowel disease. ( Sharon, P; Stenson, WF, 1985) |
| "Diffuse colitis was produced in rats by the intracolonic administration of 10% acetic acid." | 3.66 | Experimental colitis studied by colonoscopy in the rat: effect of indomethacin. ( Demers, LM; Mann, NS, 1983) |
| "Colitis was induced by intrarectal administration of 2 mL, 4% acetic acid." | 1.91 | Neuroprotective effects of methyl jasmonate in male Wistar rats exposed to delayed acetic acid-induced ulcerative colitis: involvement of antioxidant status, GFAP, and IBA-1 immunoreactivities. ( Adedeji, TG; Aluko, OM; Ijomone, OM; Jeje, SO; Nathanniel, JN; Omayone, TP; Salami, FT, 2023) |
| "Colitis was evoked by a single transrectal injection of 1 ml of 4 % acetic acid." | 1.91 | Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia activity. ( Ahmed, KA; Elbaz, EM; Essam, RM; Safwat, MH, 2023) |
| "Ulcerative colitis is characterized as a chronic immune-mediated inflammatory condition, affecting the intestinal gastroenteric tissue." | 1.91 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "Experimental ulcerative colitis was induced in rats by intrarectal acetic acid administration." | 1.91 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "Mirabegron's ability to increase adiponectin in serum and decrease glutathione, GSTM1, and catalase in the colon may account for its protective effects." | 1.91 | Mirabegron alleviates acetic acid-induced colitis in rats: Role of adiponectin and GSTM1/GSH detoxification pathway. ( Abed El Baky, MF; Hafez, HM; Mohamed, MZ; Mokhemer, SA, 2023) |
| "Mirabegron is a selective beta-3 adrenergic receptor (β-3 AR) agonist used to treat an overactive bladder." | 1.91 | Mirabegron alleviates acetic acid-induced colitis in rats: Role of adiponectin and GSTM1/GSH detoxification pathway. ( Abed El Baky, MF; Hafez, HM; Mohamed, MZ; Mokhemer, SA, 2023) |
| "Ulcerative colitis is a chronic inflammation of the colon." | 1.91 | Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue. ( Amini-Khoei, H; AnjomShoa, M; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2023) |
| "To induce ulcerative colitis, animals received 0." | 1.91 | Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue. ( Amini-Khoei, H; AnjomShoa, M; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2023) |
| "All juglone-treated groups reduced the NF-κB levels compared to the control group (p < 0." | 1.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Juglone is a phenolic bioactive compound with antimicrobial, antitumour, antioxidant, and anti-inflammatory characteristics." | 1.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Juglone was extracted from Pterocarya fraxinifolia via maceration method." | 1.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Colitis was induced in 36 male Wistar rats (n = 6), except in the sham group, 1 ml of acetic acid 4% was administered intrarectally." | 1.91 | Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023) |
| "Treatment with taurine, Tau-CS-PT-NPs, and CS-PT-NPs partly reversed these effects." | 1.72 | Taurine loaded chitosan-pectin nanoparticle shows curative effect against acetic acid-induced colitis in rats. ( Abdel-Halim, M; Ahmed, O; Elamir, A; Farid, A, 2022) |
| "Ulcerative colitis is a chronic inflammatory disease, profoundly affecting the patient's quality of life and is associated with various complications." | 1.72 | Linagliptin ameliorates acetic acid-induced colitis via modulating AMPK/SIRT1/PGC-1α and JAK2/STAT3 signaling pathway in rats. ( El-Bahy, AAZ; El-Ghannam, MS; El-Yamany, MF; Nassar, NN; Saad, MA, 2022) |
| "The available ulcerative colitis drugs exhibit limited outcomes and adverse side effects." | 1.72 | Dual role of melatonin as an anti-colitis and anti-extra intestinal alterations against acetic acid-induced colitis model in rats. ( Ahmed, O; Elamir, A; Farid, A, 2022) |
| "Ulcerative colitis is an idiopathic disease that is widely incident worldwide." | 1.72 | Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis. ( Abdelhamid, AM; Amin, NA; Cavalu, S; El-Ahwany, E; El-Azez, RA; El-Rafi, AA; El-Sandarosy, R; Elagamy, HI; Essam, M; Essam, N; Gaafar, AGA; Girgis, S; Hasaballah, A; Kamal, I; Mahmoud, F; Mansour, M; Mohamed, D; Mohammed, OA; Nasr, M; Rizk, H; Saber, S; Youssef, ME, 2022) |
| "Colitis was induced by acetic acid intrarectally." | 1.72 | Coumaric acid ameliorates experimental colitis in rats through attenuation of oxidative stress, inflammatory response and apoptosis. ( Amini-Khoei, H; Ashrafi-Dehkordi, K; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2022) |
| "Colitis was also associated with edema and severe damage to the epithelium, infiltration of inflammatory cells, and the presence of ulcers and necrosis in the colon tissue." | 1.72 | Coumaric acid ameliorates experimental colitis in rats through attenuation of oxidative stress, inflammatory response and apoptosis. ( Amini-Khoei, H; Ashrafi-Dehkordi, K; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2022) |
| "Extensive evidence suggests that gut microbiota may interact with the kidneys and play central roles in the pathogenesis of disease." | 1.72 | Gut-Kidney Impairment Process of Adenine Combined with ( Deng, N; Li, X; Peng, M; Peng, X; Qiao, B; Tan, Z; Yu, R, 2022) |
| "Phloretin (50 mg/kg) was given orally for 3 days to Wistar rats after induction for the post-treatment group and 1 day before induction to the pre-treatment group." | 1.62 | Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats. ( S K, K; V S, A, 2021) |
| "Colitis was induced by the instillation of 2 mL of 3% acetic acid solution into rat's colons." | 1.62 | An investigation of the anti-inflammatory effects of gabapentin on acetic acid-induced colitis in rats. ( Bouzari, S; Dabirian, S; Karimian, P; Molavi, M; Motavallian, A; Torshkooh, FA; Zamani, E, 2021) |
| "Colitis was induced in male Wistar rats by intrarectal instillation of 1 ml of 4% (v/v) AA." | 1.62 | Canagliflozin, an SGLT-2 inhibitor, ameliorates acetic acid-induced colitis in rats through targeting glucose metabolism and inhibiting NOX2. ( Bayoumi, AMA; Ibrahim, YF; Khalaf, HM; Khalifa, EMMA; Morsy, MA; Rifaai, RA, 2021) |
| "Colitis was induced by intra-rectal instillation of 1 ml acetic acid (4%)." | 1.56 | Biochemical and histopathological evidence for the beneficial effects of modafinil on the rat model of inflammatory bowel disease: involvement of nitric oxide pathway. ( Dehpour, AR; Dejban, P; Rahimi, N; Takzare, N, 2020) |
| "Colitis was induced in rats by acetic acid and the rats were divided into four groups where one group served as experimental control and the other groups were treated with two doses of methanol extract of dried latex of C." | 1.51 | Protection afforded by methanol extract of Calotropis procera latex in experimental model of colitis is mediated through inhibition of oxidative stress and pro-inflammatory signaling. ( Das, P; Kumar, VL; Pandey, A; Verma, S, 2019) |
| "Treatment with thymol reduced mucosal and histological damages compared to the acetic acid group." | 1.51 | Thymol reduces acetic acid-induced inflammatory response through inhibition of NF-kB signaling pathway in rat colon tissue. ( Abdollahi, A; Chamanara, M; Dehpour, A; Ghazi-Khansari, M; Nassireslami, E; Rashidian, A; Rezayat, SM, 2019) |
| "Thymol was dissolved in 0." | 1.51 | Thymol reduces acetic acid-induced inflammatory response through inhibition of NF-kB signaling pathway in rat colon tissue. ( Abdollahi, A; Chamanara, M; Dehpour, A; Ghazi-Khansari, M; Nassireslami, E; Rashidian, A; Rezayat, SM, 2019) |
| "Colitis was induced by intra-rectal administration of 2 mL of diluted acetic acid (4%) solution using a flexible plastic rubber catheter in Wistar rats." | 1.51 | Thymol reduces acetic acid-induced inflammatory response through inhibition of NF-kB signaling pathway in rat colon tissue. ( Abdollahi, A; Chamanara, M; Dehpour, A; Ghazi-Khansari, M; Nassireslami, E; Rashidian, A; Rezayat, SM, 2019) |
| "Colitis was induced with 3% (w/v) dextran sulfate sodium (DSS) in drinking water in mice for 1to7 days." | 1.48 | Betulinic acid alleviates dextran sulfate sodium-induced colitis and visceral pain in mice. ( Kalra, J; Kumar, D; Lingaraju, MC; Mathesh, K; Parida, S; Sharma, AK; Singh, TU; Tandan, SK, 2018) |
| "Ulcerative colitis is a chronic recurrent disease with incomplete treatment options." | 1.46 | The effect of sodium valproate on acetic acid-induced colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "Colitis was induced by intracolonic instillation of 2 mL of 3% acetic acid solution." | 1.46 | The effect of sodium valproate on acetic acid-induced colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "Colitis was induced by a rectal enema with 3." | 1.43 | Obestatin Accelerates the Healing of Acetic Acid-Induced Colitis in Rats. ( Ambroży, T; Bonior, J; Ceranowicz, P; Cieszkowski, J; Dembiński, A; Jaworek, J; Konturek, P; Kuśnierz-Cabala, B; Matuszyk, A; Warzecha, Z, 2016) |
| "Colitis was induced by intrarectal administration of 6% AA in BALB/c mice." | 1.43 | Flaxseed extract exhibits mucosal protective effect in acetic acid induced colitis in mice by modulating cytokines, antioxidant and antiinflammatory mechanisms. ( Gilani, AH; Iqbal, NT; Minhas, K; Palla, AH, 2016) |
| "Colitis was induced by a rectal enema with 1 ml of 4% solution of acetic acid and the severity of colitis was assessed 1 or 24 hours after induction of inflammation." | 1.42 | The influence of pretreatment with ghrelin on the development of acetic-acid-induced colitis in rats. ( Ceranowicz, D; Ceranowicz, P; Dembinski, A; Fyderek, K; Galazka, K; Maduzia, D; Matuszyk, A; Warzecha, Z, 2015) |
| "Ulcerative colitis is a disease that causes inflammation and ulcer in the lining of the large intestine." | 1.40 | Protective effect of marine mangrove Rhizophora apiculata on acetic acid induced experimental colitis by regulating anti-oxidant enzymes, inflammatory mediators and nuclear factor-kappa B subunits. ( C, G; V, VP, 2014) |
| "Tributyrin (TBU) is a good dietary source of butyrate and has beneficial effects on the maintenance of normal intestinal morphology." | 1.40 | Dietary supplementation with tributyrin alleviates intestinal injury in piglets challenged with intrarectal administration of acetic acid. ( Chen, X; Ding, B; Gong, J; Hou, Y; Liu, Y; Wang, L; Wang, Q; Wu, G; Yi, D; Yin, Y; Zhu, H, 2014) |
| "Experimentally ulcerative colitis (UC) was induced by AA in animals pretreated with three different doses of GS leaves extract (50, 100, 200 mg/kg/day) and a single dose of mesalazine (MES, 300 mg/kg/day) for seven days." | 1.40 | Pretreatment of Gymnema sylvestre revealed the protection against acetic acid-induced ulcerative colitis in rats. ( Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Aleisa, AM; Ola, MS; Parmar, MY, 2014) |
| "Malondialdehyde levels were elevated in colitis group compared to other groups (p < 0." | 1.40 | The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid. ( Can, M; Dogan, Z; Ergul, B; Filik, L; Gonultas, MA; Hucumenoglu, S; Sarikaya, M, 2014) |
| "Ulcerative colitis is a chronic inflammatory condition of the colon, and reactive oxidative metabolites (ROMs) play an important role in its pathogenesis." | 1.40 | The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid. ( Can, M; Dogan, Z; Ergul, B; Filik, L; Gonultas, MA; Hucumenoglu, S; Sarikaya, M, 2014) |
| "Acute colitis was induced by intrarectal administration of acetic acid." | 1.40 | The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid. ( Can, M; Dogan, Z; Ergul, B; Filik, L; Gonultas, MA; Hucumenoglu, S; Sarikaya, M, 2014) |
| "Colitis was induced by intrarectal inoculation of rats with 4% acetic acid for three consecutive days." | 1.40 | L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65. ( Farghaly, HS; Thabit, RH, 2014) |
| "Colitis was induced by intrarectal administration of 5% acetic acid (1ml) to Sprague-Dawley rats (200-250g; n=7-8 per group)." | 1.39 | The role of cholinergic anti-inflammatory pathway in acetic acid-induced colonic inflammation in the rat. ( Alican, I; Ercan, F; Kolgazi, M; Uslu, U; Velioglu-Ogunc, A; Yuksel, M, 2013) |
| "Ulcerative colitis is a chronic inflammatory disease and involves multiple etiological factors." | 1.39 | Protective effects of N-acetylcysteine on acetic acid-induced colitis in a porcine model. ( Chen, X; Ding, B; Hou, Y; Liu, Y; Long, M; Wang, L; Wang, Q; Wu, G; Yi, D, 2013) |
| "Quercetin (1) is an anti-inflammatory and antioxidant flavonoid." | 1.39 | Quercetin-loaded microcapsules ameliorate experimental colitis in mice by anti-inflammatory and antioxidant mechanisms. ( Baracat, MM; Casagrande, R; Colombo, BB; Fattori, V; Georgetti, SR; Guazelli, CF; Verri, WA; Vicentini, FT, 2013) |
| "Colitis was induced by acetic acid (AA)." | 1.38 | Nadroparin sodium activates Nrf2/HO-1 pathway in acetic acid-induced colitis in rats. ( Aygun, C; Bahcecioglu, IH; Demirel, U; Orhan, C; Ozercan, IH; Sahin, K; Tuzcu, M; Yalniz, M, 2012) |
| "Colitis was induced by intracolonic administration of acetic acid." | 1.37 | The effect of exopolysaccharide-producing probiotic strains on gut oxidative damage in experimental colitis. ( Aslım, B; Demirbağ, AE; Işık, S; Sengül, N; Uçar, G, 2011) |
| "Colitis was markedly ameliorated in Group III, followed by Group II, while Group IV showed little difference from the control." | 1.37 | Therapeutic effects of four molecular-weight fractions of Kurozu against dextran sulfate sodium-induced experimental colitis. ( Fujii, A; Fukuyama, N; Mori, H; Nagano, M; Shizuma, T, 2011) |
| "Colitis was rendered by instillation of 1 mL of 4% acetic acid (vol/vol) and after 1 hour, granisetron (2 mg/kg), dexamethasone (1 mg/kg), meta-chlorophenylbiguanide (mCPBG, 5 mg/kg), a 5-HT( 3) receptor agonist, or granisetron + mCPBG was given intraperitoneally." | 1.36 | Granisetron ameliorates acetic acid-induced colitis in rats. ( Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mousavizadeh, K; Rahimian, R; Rasouli, MR, 2010) |
| "Thalidomide was also effective in reducing TNFalpha levels thus contributing to its antiepileptic activity." | 1.35 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| "Inflammation was associated with decreased threshold to PTZ induced seizure." | 1.35 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| "There is higher incidence of seizures among patients with chronic inflammatory disease." | 1.35 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| "Colitis was induced by intrarectal administration of 1 mL of 5% acetic acid to Sprague-Dawley rats (200-250 g; n = 7-8/group)." | 1.35 | The effect of sildenafil, a phosphodiesterase-5 inhibitor, on acetic acid-induced colonic inflammation in the rat. ( Alican, I; Atukeren, P; Ercan, F; Ersoy, Y; Gumustas, K; Iseri, SO; Yuksel, M, 2009) |
| "Colitis was induced by intracolonic (i." | 1.34 | Protective effect of melatonin in acetic acid induced colitis in rats. ( Cerná, S; Navarová, J; Nosál'ová, V; Zakálová, M; Zeman, M, 2007) |
| "Colitis was induced by intracolonic administration of acetic acid (5%) in Sprague-Dawley rats (200-250 g)." | 1.33 | Oxytocin ameliorates oxidative colonic inflammation by a neutrophil-dependent mechanism. ( Ercan, F; Gedik, N; Işeri, SO; Sağlam, B; Sener, G; Yeğen, BC, 2005) |
| "Melatonin is a hormone involved in the transduction of photoperiodic information, and appears to modulate a variety of neural and endocrine functions." | 1.33 | Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes. ( Cevík, H; Ercan, F; Erkanli, G; Işman, CA; Yeğen, BC, 2005) |
| "Ulcerative colitis is a chronic recurrent inflammatory bowel disease in which oxidative stress has been implicated." | 1.33 | Beneficial effects of N-acetylcysteine on acetic acid-induced colitis in rats. ( Bulbuloglu, E; Buyukbese, MA; Cetinkaya, A; Ciralik, H; Kantarceken, B; Kurutas, EB, 2005) |
| "Nor-trimebutine has a blocking activity on sodium channels and a potent local anesthetic effect." | 1.33 | Effect of nor-trimebutine on neuronal activation induced by a noxious stimulus or an acute colonic inflammation in the rat. ( Bonaz, B; Mouchet, P; Sinniger, V, 2005) |
| "Nor-trimebutine was administered in rats either subcutaneously 30 min before intraperitoneal administration of acetic acid or intracolonically 30 min before intracolonic infusion of trinitrobenzenesulfonic acid." | 1.33 | Effect of nor-trimebutine on neuronal activation induced by a noxious stimulus or an acute colonic inflammation in the rat. ( Bonaz, B; Mouchet, P; Sinniger, V, 2005) |
| "Colitis was induced by intracolonic administration of acetic acid." | 1.33 | Effects of exopolysaccharide-producing probiotic strains on experimental colitis in rats. ( Aslím, B; Atalay, F; Bozkurt, H; Işik, S; Sakaoğullari, Z; Sengül, N; Uçar, G; Yücel, N, 2006) |
| "Tegaserod is a 5-HT(4) receptor partial agonist approved for the treatment of irritable bowel syndrome in women with constipation and in both men and women with chronic constipation." | 1.33 | Activation of peripheral 5-HT receptors attenuates colonic sensitivity to intraluminal distension. ( Crowell, MD; Dennis, E; Greenwood-Van Meerveld, B; Hicks, G; Venkova, K, 2006) |
| "Distal colitis was induced by intracolonic administration of 4 % acetic acid in the rat." | 1.33 | Alteration of nitrergic neuromuscular transmission as a result of acute experimental colitis in rat. ( Kim, TW; La, JH; Sung, TS; Yang, IS, 2006) |
| "Colitis was induced by intracolonic injection of 3% acetic acid." | 1.32 | Thymoquinone protects against experimental colitis in rats. ( Mahgoub, AA, 2003) |
| "Leptin or CCK-8s treatment reduced these parameters in a similar manner, while co-administration of leptin and CCK was found to be more effective in reducing the macroscopic score and WWI." | 1.32 | Anti-inflammatory effects of leptin and cholecystokinin on acetic acid-induced colitis in rats: role of capsaicin-sensitive vagal afferent fibers. ( Bozkurt, A; Cakir, B; Ercan, F; Yeğen, BC, 2003) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid in male Sprague-Dawley rats." | 1.32 | Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis. ( Kang, JW; Kim, HJ; Kim, TW; La, JH; Sung, TS; Yang, IS, 2003) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid." | 1.32 | Electroacupuncture ameliorates experimental colitis induced by acetic acid in rat. ( Kang, JW; Kim, HJ; Kim, JY; Kim, TW; Kwon, YB; La, JH; Sung, TS; Yang, IS, 2004) |
| "Colitis was induced by intracolonic instillation of a 2 ml of 4% (v/v) acetic acid solution and, 24 h later, the colonic mucosal damage was analysed macroscopically for the severity of mucosal damage, the myeloperoxidase (MPO) activity and the malondialdehyde (MDA) levels in the colon segments." | 1.31 | Anti-inflammatory effect of kaurenoic acid, a diterpene from Copaifera langsdorffi on acetic acid-induced colitis in rats. ( Gramosa, NV; Gurgel, LA; Paiva, LA; Rao, VS; Santos, FA; Silva, RM; Silveira, ER; Tomé, AR, 2002) |
| "Colitis was induced by intrarectal administration of acetic acid and followed over a period of seven days." | 1.31 | Blood purine and energy status in rats with colitis. ( Al-Awadi, FM; Khan, I, 2001) |
| "Colitis was induced by intrarectal administration of 4% acetic acid." | 1.31 | Antiinflammatory effects of Cordia myxa fruit on experimentally induced colitis in rats. ( Al-Awadi, FM; Anim, JT; Khan, I; Srikumar, TS, 2001) |
| "Colitis was assessed 72 h after induction with acetic acid." | 1.31 | Effects of Lactobacillus rhamnosus GG and Lactobacillus reuteri R2LC on acetic acid-induced colitis in rats. ( Holma, R; Korpela, R; Lohi, J; Salmenperä, P; Vapaatalo, H, 2001) |
| "Colitis was induced by intrarectal administration of 1 ml of 4% acetic acid 8 cm from anal margin." | 1.30 | Colonic muscle enhances the production of interleukin-1 beta messenger RNA in experimental colitis. ( al-Awadi, FM; Khan, I, 1997) |
| "Acute colitis was induced in male FVB mice (about 25 g) by intrarectal administration of 200 microliters of 0." | 1.30 | Induction of plasma hepatocyte growth factor in acute colitis of mice. ( Kawasaki, H; Kojo, H; Matsuno, M; Miura, K; Shiota, G; Umeki, K, 1997) |
| "Distal colitis was induced in rats by intrarectal administration of 4% acetic acid." | 1.30 | Acute experimental colitis decreases colonic circular smooth muscle contractility in rats. ( Dempsey, DT; Martin, JS; Myers, BS; Parkman, HP; Ryan, JP; Thomas, RM, 1997) |
| "Colitis was induced in male Wistar/ST strain rats by intracolonic injection of 2 ml of 5% acetic acid." | 1.30 | Protection by rebamipide against acetic acid-induced colitis in rats: relationship with its antioxidative activity. ( Osaka, T; Sakurai, K; Yamasaki, K, 1998) |
| "Colitis was induced by either flushing the colon with 2 ml 5% acetic acid or intracolonic administration of 30 mg trinitrobenzenesulphonic acid (TNB) dissolved in 0." | 1.30 | Hyperbaric oxygen: a novel modality to ameliorate experimental colitis. ( Better, OS; Karmeli, F; Okon, E; Rachmilewitz, D; Rubenstein, I, 1998) |
| "Colitis was produced in male Wistar rats by rectal instillation of 5 and 10% acetic acid, following the methods of Eliakim et al." | 1.30 | Effect of dehydroleucodine in experimental colitis in rats and mice. ( Dominguez, S; Giordano, OS; Guerreiro, E; Guzman, JA; Maria, AO; Mohamed, F; Scardapane, L; Wendel, GH, 1999) |
| "Ketotifen pretreatment significantly decreased the macroscopic damage and the increase in colonic weight." | 1.29 | Ketotifen ameliorates capsaicin-augmented acetic acid-induced colitis. ( Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D, 1995) |
| "Colitis was induced two weeks later by flushing 2 ml 5% acetic acid into the proximal colon." | 1.29 | Ketotifen ameliorates capsaicin-augmented acetic acid-induced colitis. ( Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D, 1995) |
| "Colitis was produced in male Wistar rats by rectal instillation of 1 ml of 10% acetic acid followed immediately by 1." | 1.29 | Therapeutic effect of colloid bismuth subcitrate in experimental colitis in the rat. ( Burg, Z; Dinari, G; Karmeli, F; Marcus, H; Nusinovitz, M; Zahavi, I, 1995) |
| "Colitis was induced in adult rats by the rectal administration of 5% acetic acid." | 1.29 | Induction and immunolocalization of manganese superoxide dismutase in acute acetic acid-induced colitis in the rat. ( Campbell-Thompson, M; Nick, HS; Stevenot, SA; Tannahill, CL; Valentine, JF, 1995) |
| "Oral mucositis was induced in male Golden Syrian hamsters with 5-fluorouracil 60 mg/kg intraperitoneal, days 0 and 2." | 1.29 | IL-11, a pleiotropic cytokine: exciting new effects of IL-11 on gastrointestinal mucosal biology. ( Albert, L; Keith, JC; Pfeiffer, CJ; Schaub, RG; Sonis, ST, 1994) |
| "03 mg/kg with 15% bioavailability on colonic application) was as effective as parenteral treatment at a dose of 0." | 1.29 | Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat. ( Ar'Rajab, A; Brattsand, R; Erlansson, M; Fabia, R; Svensjö, E; Willén, R, 1994) |
| "Colitis was induced in an exteriorized colonic segment by administration of 4% acetic acid for 15 s." | 1.29 | Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat. ( Ar'Rajab, A; Brattsand, R; Erlansson, M; Fabia, R; Svensjö, E; Willén, R, 1994) |
| "In patients with active ulcerative colitis, significant decreases in the number of anaerobic bacteria (Brain Heart Infusion medium), anaerobic gram-negatives and Lactobacillus were found, whereas no changes were seen in the number of aerobic bacteria and Enterobacteriaceae." | 1.29 | Impairment of bacterial flora in human ulcerative colitis and experimental colitis in the rat. ( Andersson, R; Ar'Rajab, A; Bengmark, S; Fabia, R; Jeppsson, B; Johansson, ML; Molin, G; Willén, R, 1993) |
| "Colitis was induced by intracolonic administration of 2 ml of 5% acetic acid." | 1.29 | Octreotide effectively decreases mucosal damage in experimental colitis. ( Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D, 1993) |
| "Acute colitis was induced in an isolated colonic segment by instillation of 4 per cent acetic acid for 15 s; this induces a uniform colitis after 4 days." | 1.29 | Effect of putative phospholipase A2 inhibitors on acetic acid-induced acute colitis in the rat. ( Andersson, R; Ar'Rajab, A; Bengmark, S; Fabia, R; Willén, R, 1993) |
| "Acetic acid colitis was induced 24 hr before enzyme inhibition began." | 1.29 | Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats. ( Guth, E; Guth, PH; LeDuc, LE; Reedy, T; Su, KC, 1993) |
| "In acetic acid treated rats, responses induced by carbachol, substance P, or KCl were each significantly decreased by 73%, 68%, and 55% and were similarly reduced by 42%, 77%, and 46%, respectively, in rats with T." | 1.29 | On the specificity of altered muscle function in experimental colitis in rats. ( Collins, SM; Grossi, L; McHugh, K, 1993) |
| "Distal colitis was induced by intrarectal administration of trinitrobenzene sulfonic, acetic acid, or Trichinella spiralis larvae, or by intraperitoneal injection of mitomycin C." | 1.29 | On the specificity of altered muscle function in experimental colitis in rats. ( Collins, SM; Grossi, L; McHugh, K, 1993) |
| "Acetic acid treatment resulted in increased absorption on day 4, which return to control levels by day 14." | 1.29 | Exudative and absorptive permeability in different phases of an experimental colitis condition. ( McHugh, KJ; Persson, CG; Svensjö, E, 1996) |
| "Colitis was assessed by histology and colonic levels of myeloperoxidase (a neutrophil marker enzyme)." | 1.28 | Mucosal protective activity of prostaglandin analogs in rodent colonic inflammation. ( Anglin, CP; Collins, PW; Fretland, DJ; Gasiecki, AF; Levin, S; Walsh, RE; Widomski, DL, 1992) |
| "Diffuse colitis was produced in rats by the intracolonic administration of 10% acetic acid." | 1.27 | Experimental colitis studied by colonoscopy in the rat: effect of indomethacin. ( Demers, LM; Mann, NS, 1983) |
| "Pirenzepine has been widely used for the treatment of gastric and duodenal ulcer." | 1.27 | Pirenzepine as anti-inflammatory drug in a model of experimental colitis in rat. ( Bustos-Fernández, L; Celener, D; González, E; Hamamura, S; Kofoed, JA; Ledesma de Paolo, MI; Schiffrin, E, 1987) |
| "Acute colitis was induced in 6 Sprague-Dawley rats by acetic acid enema, while 6 control animals received saline enemas." | 1.27 | Identification of experimentally induced colitis by in vitro nuclear magnetic resonance. ( Jacobs, DO; Rolandelli, RH; Rombeau, JL; Saul, SH; Settle, RG; Singer, RL; Wolf, GL, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (2.94) | 18.7374 |
| 1990's | 59 (24.79) | 18.2507 |
| 2000's | 56 (23.53) | 29.6817 |
| 2010's | 60 (25.21) | 24.3611 |
| 2020's | 56 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Aryannejad, A | 1 |
| Tabary, M | 1 |
| Noroozi, N | 1 |
| Mashinchi, B | 1 |
| Iranshahi, S | 1 |
| Tavangar, SM | 1 |
| Mohammad Jafari, R | 1 |
| Rashidian, A | 8 |
| Dehpour, AR | 6 |
| Ahmed, O | 2 |
| Abdel-Halim, M | 1 |
| Farid, A | 2 |
| Elamir, A | 2 |
| Geng, Y | 1 |
| Yue, Y | 1 |
| Guan, Q | 1 |
| Ren, Y | 1 |
| Guo, L | 1 |
| Fan, Y | 1 |
| Lu, ZM | 1 |
| Shi, JS | 1 |
| Xu, ZH | 1 |
| El-Ghannam, MS | 1 |
| Saad, MA | 1 |
| Nassar, NN | 1 |
| El-Yamany, MF | 1 |
| El-Bahy, AAZ | 1 |
| Ala, M | 1 |
| Jafari, RM | 1 |
| Nematian, H | 1 |
| Shadboorestan, A | 1 |
| Bastaki, SMA | 2 |
| Amir, N | 2 |
| Adeghate, E | 2 |
| Ojha, S | 2 |
| Dibekoğlu, C | 1 |
| Erbaş, O | 1 |
| Elhassan, YH | 1 |
| Savran, M | 1 |
| Ascı, H | 1 |
| Erzurumlu, Y | 1 |
| Ozmen, O | 1 |
| Ilhan, I | 1 |
| Sırın, MC | 1 |
| Karakuyu, NF | 1 |
| Karaibrahimoglu, A | 1 |
| Nasr, M | 1 |
| Cavalu, S | 1 |
| Saber, S | 2 |
| Youssef, ME | 1 |
| Abdelhamid, AM | 1 |
| Elagamy, HI | 1 |
| Kamal, I | 1 |
| Gaafar, AGA | 1 |
| El-Ahwany, E | 1 |
| Amin, NA | 1 |
| Girgis, S | 1 |
| El-Sandarosy, R | 1 |
| Mahmoud, F | 1 |
| Rizk, H | 1 |
| Mansour, M | 1 |
| Hasaballah, A | 1 |
| El-Rafi, AA | 1 |
| El-Azez, RA | 1 |
| Essam, M | 1 |
| Mohamed, D | 1 |
| Essam, N | 1 |
| Mohammed, OA | 1 |
| Ghasemi-Dehnoo, M | 3 |
| Amini-Khoei, H | 3 |
| Lorigooini, Z | 3 |
| Ashrafi-Dehkordi, K | 1 |
| Rafieian-Kopaei, M | 3 |
| Li, X | 1 |
| Peng, X | 1 |
| Qiao, B | 1 |
| Peng, M | 1 |
| Deng, N | 1 |
| Yu, R | 1 |
| Tan, Z | 1 |
| El-Sayed, SM | 1 |
| Nossier, MI | 1 |
| Nossier, AI | 1 |
| Şen, A | 2 |
| Özbeyli, D | 1 |
| Teralı, K | 1 |
| Göger, F | 1 |
| Yıldırım, A | 2 |
| Ertaş, B | 2 |
| Doğan, A | 1 |
| Bitiş, L | 2 |
| Şener, G | 3 |
| Cinpolat, HY | 2 |
| Buğdaycı, G | 2 |
| Şengül, N | 4 |
| Astarcı, HM | 2 |
| Abdelsameea, AA | 1 |
| Alsemeh, AE | 1 |
| Alabassery, N | 1 |
| Samy, W | 1 |
| Fawzy, A | 1 |
| Abbas, NAT | 1 |
| Omayone, TP | 2 |
| Salami, FT | 1 |
| Aluko, OM | 1 |
| Nathanniel, JN | 1 |
| Jeje, SO | 1 |
| Adedeji, TG | 1 |
| Ijomone, OM | 1 |
| Arabacı Tamer, S | 1 |
| Akbulut, S | 1 |
| Erdoğan, Ö | 1 |
| Çevik, Ö | 3 |
| Ercan, F | 8 |
| Yeğen, BÇ | 6 |
| Chen, Z | 1 |
| Nong, Y | 1 |
| Wang, Q | 4 |
| Feng, L | 1 |
| He, Y | 1 |
| Guo, B | 1 |
| Qin, Y | 1 |
| Zhong, X | 1 |
| Qin, J | 1 |
| Wei, J | 1 |
| Dong, M | 1 |
| Pan, S | 1 |
| Su, Z | 1 |
| Nooman, MU | 1 |
| Al-Kashef, AS | 1 |
| Rashad, MM | 1 |
| Khattab, AEA | 1 |
| Ahmed, KA | 2 |
| Abbas, SS | 1 |
| Elbaz, EM | 1 |
| Essam, RM | 1 |
| Safwat, MH | 1 |
| Erarslan, AS | 1 |
| Ozmerdivenli, R | 1 |
| Sirinyıldız, F | 1 |
| Gumus, E | 1 |
| Cesur, G | 1 |
| Shalaby, M | 1 |
| Abdelaziz, RR | 1 |
| Ghoneim, HA | 1 |
| Suddek, GM | 1 |
| Kayalı, DG | 1 |
| Akakın, D | 2 |
| Seoudi, SS | 1 |
| Allam, EA | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Foeniculum Vulgare Ironing on Gastrointestinal Recovery After Colorectal Resection: a Randomized Controlled Trial.[NCT03711487] | Phase 2 | 300 participants (Actual) | Interventional | 2018-10-20 | Completed | ||
| Loop Ileostomy Closure as a 23-hour Stay Procedure, a Multi-center Randomized Controlled Trial[NCT03941522] | 168 participants (Anticipated) | Interventional | 2019-06-30 | Not yet recruiting | |||
| Washed Microbiota Transplantation Combining Exclusive Enteral Nutrition Contribute to Nutritional Improvement of Patients With Crohns' Disease[NCT02897661] | 30 participants (Anticipated) | Interventional | 2016-08-31 | Recruiting | |||
| Melatonin and Ulcerative Colitis: A Pilot Clinical Trial[NCT00790478] | Phase 2 | 3 participants (Actual) | Interventional | 2009-01-31 | Terminated | ||
| A Prospective, Randomized, Double-blind, Parallel, Placebo-controlled, Multi-center Study to Investigate the Efficacy and Safety of Apomivir® in Relieving Influenza Symptoms[NCT01677689] | Phase 2 | 196 participants (Anticipated) | Interventional | 2018-09-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for acetic acid and Colitis
| Article | Year |
|---|---|
Anti-inflammatory and antioxidative effects of Camellia oleifera Abel components.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Bacteria; Camel | 2017 |
Chemical colitis.
Topics: Acetic Acid; Administration, Rectal; Animals; Anti-Infective Agents, Local; Caustics; Colitis; Colon | 2008 |
Flavonoids and arachidonic acid metabolism.
Topics: Acetates; Acetic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Carrageenan; Colitis; Disease M | 1988 |
1 trial available for acetic acid and Colitis
| Article | Year |
|---|---|
Diosmectite-zinc oxide composite improves intestinal barrier restoration and modulates TGF-β1, ERK1/2, and Akt in piglets after acetic acid challenge.
Topics: Acetic Acid; Animals; Apoptosis; Caspases; Colitis; Dietary Supplements; Disease Models, Animal; Inj | 2015 |
234 other studies available for acetic acid and Colitis
| Article | Year |
|---|---|
Anti-inflammatory Effects of Ivermectin in the Treatment of Acetic Acid-Induced Colitis in Rats: Involvement of GABA
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Baclofen; Colitis; Colon; Cyclooxygenase 2; Ivermect | 2022 |
Taurine loaded chitosan-pectin nanoparticle shows curative effect against acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Chitosan; Colitis; Drug Carriers; Drug Liberation; M | 2022 |
Cereal Vinegar Sediment Alleviates Spontaneous Ulcerative Colitis in Il-10 Deficient Mice.
Topics: Acetic Acid; Animals; Colitis; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Edible Grain; | 2021 |
Linagliptin ameliorates acetic acid-induced colitis via modulating AMPK/SIRT1/PGC-1α and JAK2/STAT3 signaling pathway in rats.
Topics: Acetic Acid; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Colitis; Cytokines; D | 2022 |
Sodium Selenite Modulates IDO1/Kynurenine, TLR4, NF-κB and Bcl2/Bax
Pathway and Mitigates Acetic Acid-Induced Colitis in Rat.
Topics: Acetic Acid; Animals; Colitis; Colon; Kynurenine; NF-kappa B; Rats; Signal Transduction; Sodium Sele | 2022 |
Dual role of melatonin as an anti-colitis and anti-extra intestinal alterations against acetic acid-induced colitis model in rats.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Glutathione; Melatonin; Rat | 2022 |
Lycopodium Mitigates Oxidative Stress and Inflammation in the Colonic Mucosa of Acetic Acid-Induced Colitis in Rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Colitis; Colitis, Ulcerat | 2022 |
Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model.
Topics: Acetic Acid; Animals; Carbamates; Colitis; Colitis, Ulcerative; Colon; Histone Deacetylase Inhibitor | 2022 |
Anti-inflammatory, anti-apoptotic, and antioxidant effects of obestatin on the colonic mucosa following acetic acid-induced colitis.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Caspase 3; Colitis; Ghrelin; Humans; M | 2023 |
"Theranekron: A Novel Anti-inflammatory Candidate for Acetic Acid-Induced Colonic Inflammation in Rats".
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis; Colon; Female; Inflammation; Inflammatory B | 2022 |
Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis.
Topics: Acetic Acid; AMP-Activated Protein Kinases; Animals; Canagliflozin; Chitosan; Colitis; Colitis, Ulce | 2022 |
Coumaric acid ameliorates experimental colitis in rats through attenuation of oxidative stress, inflammatory response and apoptosis.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Colitis; Colon; Coumaric Ac | 2022 |
Gut-Kidney Impairment Process of Adenine Combined with
Topics: Acetic Acid; Adenine; Animals; Bacteroides; Colitis; Creatinine; Diarrhea; Disease Models, Animal; F | 2022 |
Faba beans with enhanced antioxidant activity ameliorate acetic acid-induced colitis in experimental rats.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Flavonoids; Phenols; Plant Extracts; Rats; Selenium; Vi | 2022 |
Protective effects of Rubus tereticaulis leaves ethanol extract on rats with ulcerative colitis and bio-guided isolation of its active compounds: A combined in silico, in vitro and in vivo study.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Chromatography, Liquid; Colitis; Colit | 2023 |
A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid.
Topics: Acetic Acid; Animals; Colitis; Colon; Inflammation; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenes | 2023 |
A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid.
Topics: Acetic Acid; Animals; Colitis; Colon; Inflammation; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenes | 2023 |
A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid.
Topics: Acetic Acid; Animals; Colitis; Colon; Inflammation; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenes | 2023 |
A Chemically Induced Experimental Colitis Model with a Simple Combination of Acetic Acid and Trinitrobenzene Sulphonic Acid.
Topics: Acetic Acid; Animals; Colitis; Colon; Inflammation; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenes | 2023 |
Icosapent ethyl alleviates acetic acid-induced ulcerative colitis via modulation of SIRT1 signaling pathway in rats.
Topics: Acetic Acid; Animals; Caspase 3; Colitis; Colitis, Ulcerative; Collagen; Colon; Eicosapentaenoic Aci | 2023 |
Neuroprotective effects of methyl jasmonate in male Wistar rats exposed to delayed acetic acid-induced ulcerative colitis: involvement of antioxidant status, GFAP, and IBA-1 immunoreactivities.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Male; Neuroprotective Agent | 2023 |
Neuropeptide W Exhibits Preventive and Therapeutic Effects on Acetic Acid-Induced Colitis via Modulation of the Cyclooxygenase Enzyme System.
Topics: Acetic Acid; Animals; Colitis; Colon; Cyclooxygenase 2; Cytokines; Neuropeptides; Peroxidase; Rats; | 2023 |
Preventive effect of tilapia skin collagen hydrolysates on ulcerative colitis mice based on metabonomic and 16 S rRNA gene sequencing.
Topics: Acetic Acid; Actinobacteria; Animals; Bacteroidetes; Butyric Acid; Colitis; Colitis, Ulcerative; Col | 2023 |
Sophorolipids produced by Yarrowia lipolytica grown on Moringa oleifera oil cake protect against acetic acid-induced colitis in rats: impact on TLR-4/p-JNK/NFκB-p65 pathway.
Topics: Acetic Acid; Animals; Chromatography, Liquid; Colitis; Colitis, Ulcerative; Colon; Moringa oleifera; | 2023 |
Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia activity.
Topics: Acetic Acid; Acetylcholinesterase; Animals; Antioxidants; Cognitive Dysfunction; Colitis; Colitis, U | 2023 |
Therapeutic and prophylactic role of vitamin D and curcumin in acetic acid-induced acute ulcerative colitis model.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Colitis, Ulcerative; Colon; C | 2023 |
Imatinib mitigates experimentally-induced ulcerative colitis: Possible contribution of NF-kB/JAK2/STAT3/COX2 signaling pathway.
Topics: Acetic Acid; Animals; Colitis; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Glutathione; Imatinib M | 2023 |
Cotinus coggygria Scop. Attenuates Acetic Acid-Induced Colitis in Rats by Regulation of Inflammatory Mediators.
Topics: Acetic Acid; Anacardiaceae; Animals; Antioxidants; Colitis; Colon; Cytokines; Humans; Inflammation; | 2023 |
Targeted delivery of budesonide in acetic acid induced colitis: impact on miR-21 and E-cadherin expression.
Topics: Acetic Acid; Animals; Budesonide; Caco-2 Cells; Cadherins; Colitis; Humans; Hyaluronic Acid; Inflamm | 2023 |
Licofelone Attenuates Acetic Acid-Induced Colitis in Rats Through Suppression of the Inflammatory Mediators.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis; Colitis, Ulcerative; Inflammation Mediators | 2023 |
Acetic acid-induced colitis modulating potential of total crude alkaloidal extract of Picralima nitida seeds in rats.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Rats; Rats, Sprague-Dawley | 2023 |
Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor.
Topics: Acetic Acid; Animals; Colitis; Colitis, Ulcerative; Colon; Interleukin-17; Nuclear Receptor Subfamil | 2023 |
Mirabegron alleviates acetic acid-induced colitis in rats: Role of adiponectin and GSTM1/GSH detoxification pathway.
Topics: Acetic Acid; Adiponectin; Animals; Colitis; Colitis, Ulcerative; Colon; Glutathione; Male; NF-kappa | 2023 |
Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Inflammation; Lipopolysacch | 2023 |
Role of extracted phytochemicals from
Topics: Acetic Acid; Animals; Catechin; Colitis; Inflammation; Mice; Rosa | 2023 |
Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Inflammation; Male; NF-kappa B; Ni | 2023 |
Co-administration of Thymoquinone and Propolis in Liposomal Formulations as a Potential Approach for Treatment of Acetic Acid-Induced Ulcerative Colitis: Physiological and Histopathological Analysis.
Topics: Acetic Acid; Colitis; Colitis, Ulcerative; Humans; Inflammation; Liposomes; Propolis | 2023 |
Biochemical and histopathological evidence for beneficial effects of Empagliflozin pretreatment on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Benzhydryl Compounds; Colitis; Dexamethasone; Rats | 2023 |
Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Colon; Inflammation; Inflamma | 2023 |
Electrical carotid sinus nerve stimulation attenuates experimental colitis induced by acetic acid in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Carotid Sinus; Colitis; Electric Stimulation; Rats; | 2023 |
Effects of photobiomodulation in the experimental acetic acid-induced colitis: comparison between male and female.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Cytokines; Female; Humans; | 2023 |
Intestinal anti-inflammatory activity of xique-xique (Pilosocereus gounellei A. Weber ex K. Schum. Bly. Ex Rowl) juice on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Cactaceae; Colitis; Cytokines; Dose-Response Relatio | 2019 |
Biochemical and histopathological evidence for the beneficial effects of modafinil on the rat model of inflammatory bowel disease: involvement of nitric oxide pathway.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis; Disease Models, Animal; Dose-Response Relat | 2020 |
Arthrocen, an avocado-soy unsaponifiable agent, improves acetic acid-induced colitis in rat by inhibition of NF-kB signaling pathway.
Topics: Acetic Acid; Animals; Colitis; NF-kappa B; Persea; Rats; Signal Transduction | 2020 |
Cilostazol protects against acetic acid-induced colitis in rats: Possible role for cAMP/SIRT1 pathway.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Cilostazol; Colitis; Colon; Cyclic AMP; Cytoprotecti | 2020 |
Phloretin Ameliorates Acetic Acid Induced Colitis Through Modulation of Immune and Inflammatory Reactions in Rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Immunity; Inflammation; Mice; Phloretin; Rats; Rats, Wistar; R | 2021 |
Effects of garlic oil (allium sativum) on acetic acid-induced colitis in rats: Garlic oil and experimental colitis.
Topics: Acetic Acid; Allyl Compounds; Animals; Colitis; Disease Models, Animal; Garlic; Rats; Sulfides | 2020 |
Bupropion Ameliorates Acetic Acid-Induced Colitis in Rat: the Involvement of the TLR4/NF-kB Signaling Pathway.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Bupropion; Colitis; Cytochrome P-450 CYP2D6 Inhibitors; | 2020 |
The Effects of Dietary Glycine on the Acetic Acid-Induced Mouse Model of Colitis.
Topics: Acetic Acid; Animals; Clostridiales; Colitis; Disease Models, Animal; Glycine; Interleukin-10; Inter | 2020 |
Improving Animal Model of Induced Colitis by Acetic Acid in Terms of Fibrosis and Inflammation Incidence in the Colon.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Fibrosis; Incidence; Inflammation; Rat | 2022 |
Aqueous Leaf Extract of
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Inflammation; Oxidative Str | 2021 |
Anti-inflammatory effect of amitriptyline in a rat model of acetic acid-induced colitis: the involvement of the TLR4/NF-kB signaling pathway.
Topics: Acetic Acid; Administration, Oral; Amitriptyline; Animals; Anti-Inflammatory Agents; Colitis; Diseas | 2021 |
Vildagliptin attenuates acetic acid-induced colitis in rats via targeting PI3K/Akt/NFκB, Nrf2 and CREB signaling pathways and the expression of lncRNA IFNG-AS1 and miR-146a.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Apoptosis; Colitis; Cyclic AMP Response Element-Binding | 2021 |
Biochemical and histopathological effects of low dose vanadium in the healing of acetic acid-induced colitis in male wistar rats.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colon; Glutathione; Male; Rats; Rats, Wistar; Superoxid | 2021 |
Crataegus pinnatifida polysaccharide alleviates colitis via modulation of gut microbiota and SCFAs metabolism.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Bacteroides; Cell Line; Colitis; Colon; Crataegus; D | 2021 |
An investigation of the anti-inflammatory effects of gabapentin on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis; Colon; Cytokines; Gabapentin; Gene Expressi | 2021 |
Nerolidol, a sesquiterpene, attenuates oxidative stress and inflammation in acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Colitis; Cytoki | 2021 |
Dapagliflozin, an SGLT2 inhibitor, ameliorates acetic acid-induced colitis in rats by targeting NFκB/AMPK/NLRP3 axis.
Topics: Acetic Acid; AMP-Activated Protein Kinases; Animals; Benzhydryl Compounds; Colitis; Dose-Response Re | 2021 |
Inhibition of acetic acid-induced colitis in rats by new Pediococcus acidilactici strains, vitamin producers recovered from human gut microbiota.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Bacterial Agents; Bile Acids and Salts; Colitis; Co | 2021 |
Canagliflozin, an SGLT-2 inhibitor, ameliorates acetic acid-induced colitis in rats through targeting glucose metabolism and inhibiting NOX2.
Topics: Acetic Acid; Animals; Antioxidants; Canagliflozin; Colitis; Colon; Glucose; Male; NADPH Oxidase 2; O | 2021 |
Essential Role of Growth Hormone and IGF-1 in Therapeutic Effect of Ghrelin in the Course of Acetic Acid-Induced Colitis.
Topics: Acetic Acid; Animals; Colitis; Colon; Ghrelin; Growth Hormone; Insulin-Like Growth Factor I; Intesti | 2017 |
Protective effect of carvacrol on acetic acid-induced colitis.
Topics: Acetic Acid; Animals; Colitis; Cymenes; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C | 2017 |
Foeniculum vulgare essential oil ameliorates acetic acid-induced colitis in rats through the inhibition of NF-kB pathway.
Topics: Acetic Acid; Animals; Colitis; Dose-Response Relationship, Drug; Foeniculum; Male; NF-kappa B; Oils, | 2018 |
Betulinic acid alleviates dextran sulfate sodium-induced colitis and visceral pain in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Betulinic Acid; Catalase; Colitis; Dextr | 2018 |
Vinpocetine Ameliorates Acetic Acid-Induced Colitis by Inhibiting NF-κB Activation in Mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Mice; Neuroprotec | 2018 |
Sodium selenite ameliorates both intestinal and extra-intestinal changes in acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Colon; Kidney; Liver; Male; R | 2018 |
Camellia Oil ( Camellia oleifera Abel.) Modifies the Composition of Gut Microbiota and Alleviates Acetic Acid-Induced Colitis in Rats.
Topics: Acetic Acid; Animals; Bacteria; Camellia; Colitis; Gastrointestinal Microbiome; Humans; Intestinal M | 2018 |
Effects of dietary tryptophan supplementation in the acetic acid-induced colitis mouse model.
Topics: Acetic Acid; Animals; Colitis; Colon; Diet; Gene Expression Regulation; Mice; Random Allocation; RNA | 2018 |
Protection afforded by methanol extract of Calotropis procera latex in experimental model of colitis is mediated through inhibition of oxidative stress and pro-inflammatory signaling.
Topics: Acetic Acid; Animals; Calotropis; Colitis; Disease Models, Animal; Female; Inflammation; Inflammatio | 2019 |
Zeaxanthin exerts protective effects on acetic acid-induced colitis in rats via modulation of pro-inflammatory cytokines and oxidative stress.
Topics: Acetic Acid; Administration, Oral; Animals; Antioxidants; Colitis; Cytokines; Inflammation Mediators | 2019 |
Thymol reduces acetic acid-induced inflammatory response through inhibition of NF-kB signaling pathway in rat colon tissue.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis; Male; NF-kappa B; Peroxidase; Rats; Rats, W | 2019 |
Proteins from Plumeria pudica latex exhibit protective effect in acetic acid induced colitis in mice by inhibition of pro-inflammatory mechanisms and oxidative stress.
Topics: Acetic Acid; Animals; Apocynaceae; Colitis; Colon; Cytokines; Glutathione; Inflammation; Interleukin | 2019 |
Budesonide-Loaded Eudragit S 100 Nanocapsules for the Treatment of Acetic Acid-Induced Colitis in Animal Model.
Topics: Acetic Acid; Animals; Budesonide; Colitis; Disease Models, Animal; Drug Delivery Systems; Drug Liber | 2019 |
Neonatal colonic inflammation sensitizes voltage-gated Na(+) channels via upregulation of cystathionine β-synthetase expression in rat primary sensory neurons.
Topics: Acetic Acid; Aminooxyacetic Acid; Animals; Animals, Newborn; Carbocyanines; Colitis; Coloring Agents | 2013 |
Effect of hydroalcoholic extract of Hibiscus rosa sinensis Linn. leaves in experimental colitis in rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Glutathione; Hibiscus; Male; Malondial | 2012 |
The role of cholinergic anti-inflammatory pathway in acetic acid-induced colonic inflammation in the rat.
Topics: Acetic Acid; Alkaloids; Animals; Antioxidants; Cholinergic Neurons; Cholinesterase Inhibitors; Colit | 2013 |
The effect of melatonin on plasma markers of inflammation and on expression of nuclear factor-kappa beta in acetic acid-induced colitis in the rat.
Topics: Acetic Acid; Animals; Biomarkers; Colitis; Gene Expression Regulation; Inflammation; Male; Melatonin | 2013 |
Protective effects of N-acetylcysteine on acetic acid-induced colitis in a porcine model.
Topics: Acetic Acid; Acetylcysteine; Amphiregulin; Animals; Apoptosis; Caspase 3; Claudin-1; Colitis; Coliti | 2013 |
Iloprost reduces colitis induced oxidative stress: An experimental study in rats.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colon; Glutathione; Iloprost; Male; Malondialdehyde; Ox | 2013 |
Protective effect of marine mangrove Rhizophora apiculata on acetic acid induced experimental colitis by regulating anti-oxidant enzymes, inflammatory mediators and nuclear factor-kappa B subunits.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Cells, Cultured; Colitis; Colon; Cytok | 2014 |
Estrogen alleviates acetic acid-induced gastric or colonic damage via both ERα- and ERβ-mediated and direct antioxidant mechanisms in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Movement; Colitis; Cytokines; Est | 2014 |
Dietary supplementation with tributyrin alleviates intestinal injury in piglets challenged with intrarectal administration of acetic acid.
Topics: Acetic Acid; Amine Oxidase (Copper-Containing); Analysis of Variance; Animals; Caspase 3; Claudin-1; | 2014 |
Pretreatment of Gymnema sylvestre revealed the protection against acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Colitis; Colitis, Ulcerative | 2014 |
Protective effect of ginger volatile oil against acetic acid-induced colitis in rats: a light microscopic evaluation.
Topics: Acetic Acid; Animals; Colitis; Dose-Response Relationship, Drug; Male; Microscopy; Oils, Volatile; P | 2014 |
Antispasmodic and myorelaxant effects of the flavoring agent methyl cinnamate in gut: potential inhibition of tyrosine kinase.
Topics: Acetic Acid; Animals; Calcium; Calcium Channel Blockers; Carbachol; Cinnamates; Colitis; Colon; Duod | 2014 |
The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colon; Echinacea; Humans; Male; Malondialdehyde; Oxidat | 2014 |
L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65.
Topics: Acetic Acid; Animals; Arginine; Body Weight; Colitis; Colon; Guanidines; Inflammation; Male; NF-kapp | 2014 |
Protective effect of Dillenia indica L. on acetic acid induced colitis in mice.
Topics: Acetic Acid; Animals; Colitis; Colon; Dilleniaceae; Female; Mice; Organ Size; Plant Extracts; Protec | 2014 |
Gelling polysaccharide from Chondrus armatus and its oligosaccharides: the structural peculiarities and anti-inflammatory activity.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Carrageenan; Chondrus; Colitis; Colon; Gels; Hydroly | 2015 |
Antinociceptive effect of botulinum toxin type A on experimental abdominal pain.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Botulinum Toxins, Type A; Capsaicin; Colitis; Dise | 2014 |
Investigation of the effect of intracolonic melatonin gel formulation on acetic acid-induced colitis.
Topics: Acetic Acid; Animals; Colitis; Drug Compounding; Gels; Glutathione; Malondialdehyde; Melatonin; Nitr | 2016 |
The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis.
Topics: Acetic Acid; Aminopyridines; Animals; Colitis; Disease Models, Animal; Intestinal Mucosa; Intracellu | 2015 |
Anti-inflammatory effects of nesfatin-1 in rats with acetic acid - induced colitis and underlying mechanisms.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Calcium-Binding Proteins; Colitis; Dis | 2015 |
Protective Effect of Ocimum basilicum Essential Oil Against Acetic Acid-Induced Colitis in Rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Iran; Male; Ocimum basilicum; Oils, Vo | 2016 |
The influence of pretreatment with ghrelin on the development of acetic-acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis; Colon; DNA; Ghrelin; Interleukin-1beta; Intestinal Mucosa; Male; Malo | 2015 |
Obestatin Accelerates the Healing of Acetic Acid-Induced Colitis in Rats.
Topics: Acetic Acid; Animals; Colitis; Colon; DNA; Ghrelin; Injections, Intraperitoneal; Interleukin-1beta; | 2016 |
Flaxseed extract exhibits mucosal protective effect in acetic acid induced colitis in mice by modulating cytokines, antioxidant and antiinflammatory mechanisms.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cell Movement; Colitis; Col | 2016 |
Mentha longifolia protects against acetic-acid induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Colitis; Colon; Cyclohexan | 2016 |
Goat whey ameliorates intestinal inflammation on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Goats; Humans; Inflammation; Peroxidase; Rats; Rats, Wistar; T | 2016 |
The effect of sodium valproate on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis; Inflammation Mediators; Male; Random Allocation; Rats; Rats, Wistar; | 2017 |
Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat.
Topics: Acetic Acid; Analysis of Variance; Animals; Arthritis; Colitis; Cyclooxygenase Inhibitors; Cytokines | 2008 |
Do desipramine [10,11-dihydro-5-[3-(methylamino) propyl]-5H-dibenz[b,f]azepine monohydrochloride] and fluoxetine [N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propan-1-amine] ameliorate the extent of colonic damage induced by acetic acid in rats?
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Desipramine; Dose-Response Re | 2008 |
The effect of iNOS inhibitors and hyperbaric oxygen treatment in a rat model of experimental colitis.
Topics: Acetic Acid; Animals; Colitis; Combined Modality Therapy; Disease Models, Animal; Female; Guanidines | 2009 |
Optimized prodrug approach: a means for achieving enhanced anti-inflammatory potential in experimentally induced colitis.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Glycine; Ketoprofen; Prodrug | 2009 |
The effect of sildenafil, a phosphodiesterase-5 inhibitor, on acetic acid-induced colonic inflammation in the rat.
Topics: Acetic Acid; Analysis of Variance; Animals; Colitis; Glutathione; Interleukin-1beta; Luminescence; M | 2009 |
Granisetron ameliorates acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Biguanides; Colitis; Colon; Dexamethasone; Disease M | 2010 |
Effectiveness of budesonide-succinate-dextran conjugate as a novel prodrug of budesonide against acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Budesonide; Colitis; Dextrans; Hydrocortisone; Male; | 2010 |
The effect of exopolysaccharide-producing probiotic strains on gut oxidative damage in experimental colitis.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Female; Lactobacillus delbrueckii; Lip | 2011 |
Protective effects of Kurozu and Kurozu Moromimatsu on dextran sulfate sodium-induced experimental colitis.
Topics: Acetic Acid; Animals; Colitis; Dextran Sulfate; Fermentation; Mice; Oryza; Weight Loss | 2011 |
Effect of royal jelly on experimental colitis Induced by acetic acid and alteration of mast cell distribution in the colon of rats.
Topics: Acetic Acid; Animals; Cells, Cultured; Colitis; Fatty Acids; Female; Indicators and Reagents; Intest | 2010 |
Role of bone marrow-derived monocytes/macrophages in the repair of mucosal damage caused by irradiation and/or anticancer drugs in colitis model.
Topics: Acetic Acid; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Biomarkers; Bone Marro | 2010 |
Protective effect of aqueous extract of Bombax malabaricum DC on experimental models of inflammatory bowel disease in rats and mice.
Topics: Acetic Acid; Animals; Bombax; Colitis; Disease Models, Animal; Female; India; Indomethacin; Inflamma | 2011 |
Therapeutic effects of four molecular-weight fractions of Kurozu against dextran sulfate sodium-induced experimental colitis.
Topics: Acetic Acid; Animals; Body Weight; Colitis; Colon; Dextran Sulfate; Female; Mice; Mice, Inbred C57BL | 2011 |
Beneficial effects of THSG on acetic acid-induced experimental colitis: involvement of upregulation of PPAR-γ and inhibition of the Nf-Κb inflammatory pathway.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cyclooxygenase 2; Cyclooxyge | 2011 |
Nadroparin sodium activates Nrf2/HO-1 pathway in acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Cyclooxygenase 2; Heme Oxygenase-1; Inflammatory Bowel Disease | 2012 |
Effect of Boswellia serrata on antioxidant status in an experimental model of colitis rats induced by acetic acid.
Topics: Acetic Acid; Anal Canal; Animals; Boswellia; Colitis; Colon; Disease Models, Animal; Drug Evaluation | 2012 |
Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: therapeutic efficacy and possible mechanisms of action.
Topics: Acetic Acid; Acute Disease; Administration, Oral; Animals; Anti-Inflammatory Agents; Apoptosis; Cell | 2012 |
Augmented activity of the pelvic nerve afferent mediated by TRP channels in dextran sulfate sodium (DSS)-induced colitis of rats.
Topics: Acetic Acid; Animals; Capsaicin; Colitis; Dextran Sulfate; Electrophysiological Phenomena; Male; Neu | 2012 |
A novel tylophorine analog NK-007 ameliorates colitis through inhibition of innate immune response.
Topics: Acetic Acid; Animals; Cell Line; Colitis; Cytoskeletal Proteins; Dextran Sulfate; Immunity, Innate; | 2012 |
Enhanced excitability of guinea pig inferior mesenteric ganglion neurons during and following recovery from chemical colitis.
Topics: Acetic Acid; Action Potentials; Animals; Anthracenes; Colitis; Disease Models, Animal; Electrophysio | 2012 |
Effect of exclusive enteral nutrition on gut microflora function in children with Crohn's disease.
Topics: Acetic Acid; Adolescent; Anus Diseases; Butyric Acid; Case-Control Studies; Child; Colitis; Crohn Di | 2012 |
Quercetin-loaded microcapsules ameliorate experimental colitis in mice by anti-inflammatory and antioxidant mechanisms.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Capsules; Coliti | 2013 |
Morphologic and morphometric analyses of acetic acid-induced colitis in rats after treatment with enemas from Myracrodruon urundeuva Fr. All. (Aroeira do Sertão).
Topics: Acetic Acid; Anacardiaceae; Animals; Brazil; Colitis; Collagen; Colon; Enema; Eosinophils; Leukocyte | 2002 |
Prevention of acetic acid-induced colitis by desferrithiocin analogs in a rat model.
Topics: Acetic Acid; Animals; Colitis; Dihydropyridines; Disease Models, Animal; Drug Interactions; Intestin | 2003 |
Acetic acid-derived prostaglandin-dependent colonic adaptive cytoprotection is preserved in chronic colitis: role of cyclo-oxygenase.
Topics: Acetic Acid; Animals; Colitis; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Rela | 2003 |
Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug.
Topics: Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; | 2003 |
Thymoquinone protects against experimental colitis in rats.
Topics: Acetic Acid; Animals; Benzoquinones; Colitis; Colon; Disease Models, Animal; Dose-Response Relations | 2003 |
Evaluating the prophylactic potential of zafirlukast against the toxic effects of acetic acid on the rat colon.
Topics: Acetic Acid; Animals; Catalase; Colitis; Colon; Coloring Agents; Glutathione; Indoles; Leukotriene A | 2003 |
Anti-inflammatory effect of kaurenoic acid, a diterpene from Copaifera langsdorffi on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Administration, Oral; Administration, Rectal; Animals; Anti-Inflammatory Agents, Non-St | 2002 |
Anti-inflammatory effects of leptin and cholecystokinin on acetic acid-induced colitis in rats: role of capsaicin-sensitive vagal afferent fibers.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Capsaicin; Cholecystokinin; Colitis; Colon; Female; | 2003 |
Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Coumaric Acids; Cyclooxygena | 2003 |
Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis.
Topics: Acetic Acid; Animals; Biomarkers; Colitis; Disease Models, Animal; Inflammation; Irritable Bowel Syn | 2003 |
Estradiol treatment ameliorates acetic acid-induced gastric and colonic injuries in rats.
Topics: Acetic Acid; Animals; Colitis; Dose-Response Relationship, Drug; Epithelium; Estradiol; Female; Male | 2003 |
The anti-inflammatory effect of leptin on experimental colitis: involvement of endogenous glucocorticoids.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis; Colon; Dehydration; Female; Glucocorticoids | 2004 |
Protective effect of Copaifera langsdorffii oleo-resin against acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Balsams; Colitis; Fabaceae; Male; Plant Bark; Plant Extracts; Rats; Rats, Wist | 2004 |
Electroacupuncture ameliorates experimental colitis induced by acetic acid in rat.
Topics: Acetic Acid; Adrenergic beta-Antagonists; Animals; Carbachol; Cholinergic Agonists; Colitis; Electro | 2004 |
Effects of the neutrophil elastase inhibitor (ONO-6818) on acetic acid induced colitis in Syrian hamsters.
Topics: Acetic Acid; Animals; Colitis; Cricetinae; Hemoglobins; Leukocyte Elastase; Male; Mesocricetus; Oxad | 2004 |
Role of mucosal mast cells in visceral hypersensitivity in a rat model of irritable bowel syndrome.
Topics: Acetic Acid; Animals; Cell Count; Colitis; Hypersensitivity; Image Processing, Computer-Assisted; In | 2004 |
Increase in neurokinin-1 receptor-mediated colonic motor response in a rat model of irritable bowel syndrome.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Gastrointestinal Motility; Irritable B | 2005 |
Oxytocin ameliorates oxidative colonic inflammation by a neutrophil-dependent mechanism.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colon; Female; Gastrointestinal Tract; Glutathione; Imm | 2005 |
The effects of selective cyclooxygenase-2 inhibitors, celecoxib and rofecoxib, on experimental colitis induced by acetic acid in rats.
Topics: Acetic Acid; Animals; Celecoxib; Colitis; Cyclooxygenase Inhibitors; Lactones; Male; Pyrazoles; Rats | 2005 |
Disturbances in epithelial ionic secretion in different experimental models of colitis.
Topics: Acetic Acid; Acute Disease; Alkylating Agents; Animals; Animals, Genetically Modified; Chloramines; | 2005 |
Exposure to continuous darkness ameliorates gastric and colonic inflammation in the rat: both receptor and non-receptor-mediated processes.
Topics: Acetic Acid; Animals; Colitis; Darkness; Ethanol; Female; Gastric Mucosa; Inflammation; Intestinal M | 2005 |
Beneficial effects of N-acetylcysteine on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Acetylcysteine; Animals; Colitis; Glutathione; Lipid Peroxidation; Male; Peroxidase; Ra | 2005 |
Effect of nor-trimebutine on neuronal activation induced by a noxious stimulus or an acute colonic inflammation in the rat.
Topics: Abdominal Pain; Acetic Acid; Anesthetics, Local; Animals; Colitis; Immunohistochemistry; Injections, | 2005 |
Effect of adrenomedullin administration on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Adrenomedullin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Indicators a | 2005 |
Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis.
Topics: Acetic Acid; Animals; Colitis; Cytokines; Disease Models, Animal; Intestinal Mucosa; Male; Necrosis; | 2005 |
Effects of intestinal trefoil, factor on colonic mucosa in experimental colitis of rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Female; Intestinal Mucosa; Male; Malondialdehyde; Nitric Oxide | 2005 |
Milk whey culture with Propionibacterium freudenreichii ET-3 is effective on the colitis induced by 2,4,6-trinitrobenzene sulfonic acid in rats.
Topics: Acetic Acid; Animals; Cattle; Colitis; Colon; Culture Media; Male; Milk; Probiotics; Propionates; Pr | 2005 |
Effects of exopolysaccharide-producing probiotic strains on experimental colitis in rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Female; Intestinal Mucosa; Irritants; | 2006 |
Activation of peripheral 5-HT receptors attenuates colonic sensitivity to intraluminal distension.
Topics: Acetic Acid; Animals; Colitis; Colon; Dose-Response Relationship, Drug; Gastrointestinal Agents; Ind | 2006 |
Alteration of nitrergic neuromuscular transmission as a result of acute experimental colitis in rat.
Topics: Acetic Acid; Animals; Colitis; Colon; Indicators and Reagents; Male; Muscle Contraction; Muscle, Smo | 2006 |
Protective effect of comaruman, a pectin of cinquefoil Comarum palustre L., on acetic acid-induced colitis in mice.
Topics: Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Intestinal Mucosa; Male; Mice; Pectins | 2006 |
The effects of Gingko biloba extract on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Antioxidants; Biomarkers; Colitis; Disease Models, Animal; Fibrosis; Ginkgo bi | 2006 |
Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice.
Topics: Acetic Acid; Animals; Antioxidants; Cell Adhesion; Colitis; Colon; Disease Models, Animal; Intestina | 2006 |
Protective effect of melatonin in acetic acid induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis; Colon; Glutathione; Male; Melatonin; Peroxidase; Rats; Rats, Wistar | 2007 |
Glutamine inhibits over-expression of pro-inflammatory genes and down-regulates the nuclear factor kappaB pathway in an experimental model of colitis in the rat.
Topics: Acetic Acid; Animals; Biomarkers; Colitis; Cyclooxygenase 2; Disease Models, Animal; Down-Regulation | 2007 |
Acetate inhibits NFAT activation in T cells via importin beta1 interference.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; beta Karyopherins; Colitis; Dermatitis; Dinitrofluor | 2007 |
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Coliti | 2008 |
Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid.
Topics: Acetic Acid; Animals; Catechin; Colitis; Cytokines; Indicators and Reagents; Interferon-gamma; Intes | 2008 |
Increased 5-hydroxytryptamine mediates post-inflammatory visceral hypersensitivity via the 5-hydroxytryptamine 3 receptor in rats.
Topics: 5-Hydroxytryptophan; Acetic Acid; Animals; Carbolines; Colitis; Granisetron; Hypersensitivity; Intes | 2008 |
Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models.
Topics: Acetates; Acetic Acid; Animals; Ascitic Fluid; Cell Separation; Clostridium Infections; Colitis; Cri | 1984 |
Experimental colitis studied by colonoscopy in the rat: effect of indomethacin.
Topics: Acetates; Acetic Acid; Animals; Biopsy; Colitis; Colon; Colonoscopy; Dinoprostone; Fiber Optic Techn | 1983 |
Colitis and colonic mucosal barrier dysfunction.
Topics: Acetates; Acetic Acid; Animals; Carbon Radioisotopes; Cell Membrane Permeability; Colitis; Colon; Di | 1995 |
Ketotifen ameliorates capsaicin-augmented acetic acid-induced colitis.
Topics: Acetates; Acetic Acid; Amino Acid Oxidoreductases; Animals; Capsaicin; Colitis; Colon; Intestinal Mu | 1995 |
Molecular cloning of mouse intestinal trefoil factor and its expression during goblet cell changes.
Topics: Acetates; Acetic Acid; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Colitis; Gen | 1995 |
Therapeutic effect of colloid bismuth subcitrate in experimental colitis in the rat.
Topics: Acetates; Acetic Acid; Animals; Bismuth; Colitis; Dinoprostone; Intestinal Mucosa; Male; Organometal | 1995 |
Induction and immunolocalization of manganese superoxide dismutase in acute acetic acid-induced colitis in the rat.
Topics: Acetates; Acetic Acid; Acute Disease; Animals; Blotting, Northern; Blotting, Western; Colitis; Colon | 1995 |
Another model of acetic acid-induced colitis in the rat.
Topics: Acetates; Acetic Acid; Animals; Burns, Chemical; Colitis; Disease Models, Animal; Rats; Ulcer | 1994 |
IL-11, a pleiotropic cytokine: exciting new effects of IL-11 on gastrointestinal mucosal biology.
Topics: Acetates; Acetic Acid; Animals; Animals, Genetically Modified; beta 2-Microglobulin; Colitis; Cricet | 1994 |
Effects of intracolonic acetic acid on responses to colorectal distension in the rat.
Topics: Acetates; Acetic Acid; Animals; Blood Pressure; Catheterization; Colitis; Colon; Electromyography; G | 1995 |
Acetic acid-induced colitis in normal and essential fatty acid deficient rats.
Topics: Acetates; Acetic Acid; Acid Phosphatase; Animals; Colitis; Dietary Fats; Dinoprostone; Fatty Acids; | 1995 |
Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat.
Topics: Acetates; Acetic Acid; Administration, Topical; Animals; Anti-Inflammatory Agents; Body Weight; Bude | 1994 |
Neutrophil-independence of the initiation of colonic injury. Comparison of results from three models of experimental colitis in the rat.
Topics: Acetates; Acetic Acid; Animals; Colitis; Colon; Ethanol; Leukocyte Count; Male; Neutropenia; Neutrop | 1994 |
Impairment of bacterial flora in human ulcerative colitis and experimental colitis in the rat.
Topics: Acetates; Acetic Acid; Animals; Bacteria, Anaerobic; Colitis; Colitis, Ulcerative; Colon; Enterobact | 1993 |
The leukocyte recruitment inhibitor, NPC 15669 accelerates healing in acetic acid-induced colitis.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Disease Mod | 1993 |
Malabsorption of zinc in rats with acetic acid-induced enteritis and colitis.
Topics: Acetates; Acetic Acid; Animals; Colitis; Colon; Enteritis; Ileum; Intestinal Absorption; Intestinal | 1993 |
Octreotide effectively decreases mucosal damage in experimental colitis.
Topics: Acetates; Acetic Acid; Animals; Colitis; Colon; Intestinal Mucosa; Leukotriene B4; Male; Octreotide; | 1993 |
NPC 15669, an inhibitor of neutrophil recruitment, is efficacious in acetic acid-induced colitis in rats.
Topics: Acetates; Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capil | 1993 |
Acetic acid-induced colitis results in bystander ileal injury.
Topics: Acetates; Acetic Acid; Animals; Body Fluids; Cecum; Colitis; Colon; Disease Models, Animal; Ileum; I | 1993 |
Effect of putative phospholipase A2 inhibitors on acetic acid-induced acute colitis in the rat.
Topics: Acetates; Acetic Acid; Acetophenones; Animals; Colitis; Colon; Enzyme Activation; Female; Intestinal | 1993 |
Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats.
Topics: Acetates; Acetic Acid; Analysis of Variance; Animals; Benzoquinones; Colitis; Colon; Cyclooxygenase | 1993 |
On the specificity of altered muscle function in experimental colitis in rats.
Topics: Acetates; Acetic Acid; Animals; Carbachol; Colitis; Colon; Dose-Response Relationship, Drug; Female; | 1993 |
On the suppression of food intake in experimental models of colitis in the rat.
Topics: Acetates; Acetic Acid; Administration, Rectal; Animals; Body Weight; Colitis; Eating; Indoles; Indom | 1993 |
The role of transient mucosal ischemia in acetic acid-induced colitis in the rat.
Topics: Acetic Acid; Animals; Catalase; Colitis; Colon; Female; Intestinal Mucosa; Ischemia; Rats; Rats, Spr | 1996 |
Kinetics of cytokine expression during healing of acute colitis in mice.
Topics: Acetic Acid; Acute Disease; Animals; Base Sequence; Cell Line; Colitis; Cytokines; Female; Kinetics; | 1996 |
cDNA cloning of rat pS2 peptide and expression of trefoil peptides in acetic acid-induced colitis.
Topics: Acetic Acid; Amino Acid Sequence; Animals; Base Sequence; Cell Differentiation; Cell Division; Cloni | 1996 |
Evaluation of the role of mast cells in the progression of acetic acid-induced colitis in mice.
Topics: Acetic Acid; Animals; Colitis; Intestinal Mucosa; Ketotifen; Male; Mast Cells; Mice; Mice, Inbred St | 1996 |
Presence of immunocytes and sulfidopeptide leukotrienes in the inflamed guinea pig distal colon.
Topics: Acetic Acid; Animals; Calcimycin; Calcium; Colitis; Eosinophil Peroxidase; Eosinophils; Guinea Pigs; | 1996 |
Exudative and absorptive permeability in different phases of an experimental colitis condition.
Topics: Acetic Acid; Animals; Cell Membrane Permeability; Chromium Radioisotopes; Colitis; Disease Models, A | 1996 |
Application of natural products in experimental models of intestinal inflammation in rats.
Topics: Acetic Acid; Alkaline Phosphatase; Animals; Biomarkers; Colitis; Disease Models, Animal; Humans; Inf | 1996 |
Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis.
Topics: Acetic Acid; Aminosalicylic Acids; Animals; Antioxidants; Butylated Hydroxytoluene; Colitis; Colitis | 1996 |
Is nitric oxide and heparin treatment justified in inflammatory bowel disease? An experimental study.
Topics: Acetic Acid; Animals; Arginine; Capillaries; Colitis; Enzyme Inhibitors; Heparin; Interleukin-6; Mal | 1996 |
The prophylactic effects of superoxide dismutase, catalase, desferrioxamine, verapamil and disulfiram in experimental colitis.
Topics: Acetic Acid; Animals; Calcium Channel Blockers; Catalase; Colitis; Colonic Diseases; Deferoxamine; D | 1997 |
Effect of preinduction of heat shock proteins on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Blotting, Western; Chaperonin 60; Colitis; Colon; Heat-Shock Proteins; HSP72 H | 1997 |
Colonic muscle enhances the production of interleukin-1 beta messenger RNA in experimental colitis.
Topics: Acetic Acid; Animals; Colitis; Colon; Interleukin-1; Male; Muscle Contraction; Muscle, Smooth; Polym | 1997 |
Induction of plasma hepatocyte growth factor in acute colitis of mice.
Topics: Acetic Acid; Acute Disease; Administration, Rectal; Animals; Biomarkers; Colitis; Disease Models, An | 1997 |
Evaluation of the role of neutrophils in the pathogenesis of acetic acid-induced colitis in mice.
Topics: Acetic Acid; Animals; Colitis; Colon; Cyclophosphamide; Immunosuppressive Agents; Intestinal Mucosa; | 1997 |
Rutoside as mucosal protective in acetic acid-induced rat colitis.
Topics: Acetic Acid; Administration, Oral; Animals; Colitis; Colon; Intestinal Absorption; Intestinal Mucosa | 1997 |
Acute experimental colitis decreases colonic circular smooth muscle contractility in rats.
Topics: Acetic Acid; Acetylcholine; Acute Disease; Animals; Colitis; Colon; Gastrointestinal Motility; GTP-B | 1997 |
Antiinflammatory effects of human milk on chemically induced colitis in rats.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Inflammatory Agents; Colitis; Enteral Nutrition; Female; H | 1997 |
Anti-P-selectin antibody exacerbated inflammatory responses in acetic acid-induced colitis.
Topics: Acetic Acid; Animals; Antibodies; Colitis; Colon; Immunoglobulin G; Inflammation; Male; Nitric Oxide | 1997 |
Protection by rebamipide against acetic acid-induced colitis in rats: relationship with its antioxidative activity.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Antioxidants; Colitis; Intestinal Mucosa; Lipid Pe | 1998 |
Thermotolerance of Escherichia coli O157:H7 ATCC 43,894, Escherichia coli B, and an rpoS-deficient mutant of Escherichia coli O157:H7 ATCC 43,895 following exposure to 1.5% acetic acid.
Topics: Acetic Acid; Colitis; Colony Count, Microbial; Culture Media; Escherichia coli; Escherichia coli O15 | 1998 |
Colitis-induced changes in the level of trace elements in rat colon and other tissues.
Topics: Acetic Acid; Animals; Colitis; Colon; Copper; Glutathione Peroxidase; Liver; Male; Manganese; Peroxi | 1998 |
Hyperbaric oxygen: a novel modality to ameliorate experimental colitis.
Topics: Acetic Acid; Animals; Colitis; Hyperbaric Oxygenation; Intestinal Mucosa; Male; Nitric Oxide Synthas | 1998 |
Immediate-early gene expression in the inferior mesenteric ganglion and colonic myenteric plexus of the guinea pig.
Topics: Acetic Acid; Animals; Capsaicin; Catheterization; Colitis; Ganglia, Autonomic; Gene Expression Regul | 1999 |
Experimental colitis increases blood-brain barrier permeability in rabbits.
Topics: Acetic Acid; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Capillary Permeability; Cerebrovas | 1999 |
Anti-inflammatory activity of phycocyanin extract in acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis; Eukaryota; Male; Mesalamine; Microscopy, El | 1999 |
Effects of histamine H1 antagonist dithiaden on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Benzothiepins; Colitis; Colon; gamma-Glutamyltransferase; Histamine; Histamine | 1999 |
Effect of DA-6034, a derivative of flavonoid, on experimental animal models of inflammatory bowel disease.
Topics: Acetic Acid; Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Anti-Inflammatory Age | 1999 |
Effect of dehydroleucodine in experimental colitis in rats and mice.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Colitis; Colon; Diarrhea; Irritants; Lactones; Male; Mice; | 1999 |
Protective effect of stobadine in experimental colitis.
Topics: Acetic Acid; Animals; Antioxidants; Carbolines; Colitis; Free Radical Scavengers; Gastrointestinal H | 1999 |
Comparative study of D-002 versus sulfasalazine on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis; Fatty Alcohols; Leukotriene B4; Male; Neutrophils; Rats; Rats, Spragu | 2000 |
Upregulation of HGF activator inhibitor type 1 but not type 2 along with regeneration of intestinal mucosa.
Topics: Acetic Acid; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Colitis; Digestive Sys | 2000 |
Blood purine and energy status in rats with colitis.
Topics: Acetic Acid; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anim | 2001 |
Antiinflammatory effects of Cordia myxa fruit on experimentally induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Boraginaceae; Colitis; Colon; Fruit; G | 2001 |
Effects of Lactobacillus rhamnosus GG and Lactobacillus reuteri R2LC on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Body Weight; Colitis; Colon; Cyclooxygenase 2; Eating; Humans; Isoenzymes; Lac | 2001 |
FR167653, a potent suppressant of interleukin-1 and tumor necrosis factor-alpha production, ameliorates colonic lesions in experimentally induced acute colitis.
Topics: Acetic Acid; Acute Disease; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 2001 |
Effect of N-acetylcysteine on colitis induced by acetic acid in rats.
Topics: Acetic Acid; Acetylcysteine; Animals; Colitis; Dose-Response Relationship, Drug; Glutathione; Male; | 2000 |
Morphological study of the regeneration mechanism of acetic acid-injured colon crypts in the rat.
Topics: Acetic Acid; Animals; Colitis; Colon; Intestinal Mucosa; Male; Microscopy, Electron, Scanning; Rats; | 2000 |
Selective modulation of PKC isozymes by inflammation in canine colonic circular muscle cells.
Topics: Acetic Acid; Acetylcholine; Animals; Blotting, Western; Central Nervous System Depressants; Colitis; | 2002 |
Effect of BP 2.94, a histamine H3-receptor agonist prodrug, on different models of colitis.
Topics: Acetic Acid; Animals; Colitis; Ethanol; Histamine Agonists; Histamine Antagonists; Imidazoles; Imine | 2002 |
Antisense inhibition of cyclooxygenase-2 causes a selective suppression of the Na+-H+ exchanger isoform 3 in rat kidney in experimental colitis.
Topics: Acetic Acid; Animals; Antibody Specificity; Blotting, Western; Body Weight; Colitis; Cyclooxygenase | 2002 |
Effects of phosphatidylcholine and phosphatidylinositol on acetic-acid-induced colitis in the rat.
Topics: Acetates; Acetic Acid; Animals; Colitis; Female; Intestinal Absorption; Intestinal Mucosa; Phosphati | 1992 |
A comparative analysis of two models of colitis in rats.
Topics: Acetates; Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Ethanol; Intestinal Mucosa; | 1992 |
Mucosal protective activity of prostaglandin analogs in rodent colonic inflammation.
Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Colitis; Disease Models, Animal; Intestinal Mucos | 1992 |
Agents capable of eliminating reactive oxygen species. Catalase, WR-2721, or Cu(II)2(3,5-DIPS)4 decrease experimental colitis.
Topics: Acetates; Acetic Acid; Amifostine; Animals; Catalase; Colitis; Female; Luminescent Measurements; Rat | 1992 |
Increased phospholipase A2 activity in peritoneal leukocytes in rat experimental colitis.
Topics: Acetates; Acetic Acid; Animals; Arthus Reaction; Colitis; Dexamethasone; Dinitrochlorobenzene; Disea | 1992 |
Ketotifen effectively prevents mucosal damage in experimental colitis.
Topics: Acetates; Acetic Acid; Animals; Colitis; Colon; Disease Models, Animal; Intestinal Mucosa; Ketotifen | 1992 |
Misoprostol attenuates acetic acid-induced increases in mucosal permeability and inflammation: role of blood flow.
Topics: Acetates; Acetic Acid; Administration, Rectal; Alprostadil; Animals; Anti-Ulcer Agents; Colitis; Col | 1991 |
Mucosal vascular stasis precedes loss of viability of endothelial cells in rat acetic acid colitis.
Topics: Acetates; Acetic Acid; Animals; Colitis; Colon; Endothelium, Vascular; Intestinal Mucosa; Ischemia; | 1991 |
The effect of essential fatty acid deficiency on eicosanoid production in the inflamed rat colonic mucosa.
Topics: Acetates; Acetic Acid; Animals; Colitis; Eicosanoids; Fatty Acids, Essential; Female; In Vitro Techn | 1990 |
Pirenzepine as anti-inflammatory drug in a model of experimental colitis in rat.
Topics: Acetates; Acetic Acid; Animals; Colitis; Colon; Colonic Diseases; Edema; Male; Mucus; Pirenzepine; R | 1987 |
Enterohepatic circulation of bacterial chemotactic peptide in rats with experimental colitis.
Topics: Acetates; Acetic Acid; Animals; Chemotactic Factors; Colitis; Colon; Enterohepatic Circulation; Iodi | 1988 |
Metabolism of arachidonic acid in acetic acid colitis in rats. Similarity to human inflammatory bowel disease.
Topics: Acetates; Acetic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure L | 1985 |
Identification of experimentally induced colitis by in vitro nuclear magnetic resonance.
Topics: Acetates; Acetic Acid; Animals; Body Water; Colitis; Disease Models, Animal; In Vitro Techniques; In | 1985 |