acetic acid has been researched along with Colitis Gravis in 159 studies
Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The study used the acetic acid model of colitis and thereafter delayed the healing process by the administration of indomethacin (Indo) (2 mg/kg, SC)." | 8.31 | Neuroprotective effects of methyl jasmonate in male Wistar rats exposed to delayed acetic acid-induced ulcerative colitis: involvement of antioxidant status, GFAP, and IBA-1 immunoreactivities. ( Adedeji, TG; Aluko, OM; Ijomone, OM; Jeje, SO; Nathanniel, JN; Omayone, TP; Salami, FT, 2023) |
| " This study evaluated the anti-inflammatory effects of licofelone on acetic acid-induced colitis in rats." | 8.31 | Licofelone Attenuates Acetic Acid-Induced Colitis in Rats Through Suppression of the Inflammatory Mediators. ( Abdolghaffari, AH; Abdollahi, AR; Baeeri, M; Dehpour, AR; Khayatan, D; Lashgari, NA; Momtaz, S; Roudsari, NM; Shahraki, FN, 2023) |
| "Sprague Dawley rats were treated with oral 500 mg/kg sulphasalazine or 30, 100, and 300 mg/kg of PNE daily for 8 days with induction of colitis on the fourth day with acetic acid." | 8.31 | Acetic acid-induced colitis modulating potential of total crude alkaloidal extract of Picralima nitida seeds in rats. ( Boakye-Gyasi, E; Okyere, PD; Oppong-Kyekyeku, J; Osafo, N; Otu-Boakye, SA; Yeboah, KO, 2023) |
| "Experimental ulcerative colitis was induced in rats by intrarectal acetic acid administration." | 8.31 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "This study shows the therapeutic potential of topotecan in attenuating ulcerative colitis in rats probably via inhibition of the RORγT transcription factor and downstream mediators of Th-17 cells." | 8.31 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "In this study, the therapeutic effect of quinic acid (QA), which has anti-inflammatory activity, was investigated on acetic acid-induced colitis in male Wistar rats." | 8.31 | Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways. ( Amini-Khoei, H; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M; Sabzevary-Ghahfarokhi, M, 2023) |
| "Ulcerative colitis (UC) was induced in rats by acetic acid intrarectally, and the protective effects of QA in 10, 30, 60, and 100 mg/kg doses were investigated." | 8.31 | Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways. ( Amini-Khoei, H; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M; Sabzevary-Ghahfarokhi, M, 2023) |
| "To investigate the effect of givinostat treatment in acetic acid-induced ulcerative colitis model in rats." | 8.12 | Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model. ( Dibekoğlu, C; Erbaş, O, 2022) |
| " Rats were randomly divided into three equal groups, and colitis was induced on 20 rats by rectal administration of %4 solutions of acetic acid." | 8.12 | Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model. ( Dibekoğlu, C; Erbaş, O, 2022) |
| "Givinostat, a good protector and regenerator of tissue and an anti-inflammatory agent, may be involved in the treatment of colitis in the future." | 8.12 | Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model. ( Dibekoğlu, C; Erbaş, O, 2022) |
| " major in rats with acetic acid-induced ulcerative colitis (UC)." | 8.12 | Evaluation of anti-inflammatory effects of leaf and seed extracts of Plantago major on acetic acid-induced ulcerative colitis in rats. ( Farid, A; Motevalian, M; Noori, M; Sheibani, M; Shojaii, A, 2022) |
| " Present study is designed to evaluate the preventative activities of GS against acetic acid (AA)-induced ulcerative colitis in Wistar rats." | 7.80 | Pretreatment of Gymnema sylvestre revealed the protection against acetic acid-induced ulcerative colitis in rats. ( Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Aleisa, AM; Ola, MS; Parmar, MY, 2014) |
| "To investigate the effects of glutamine on the colonic mucosa of mice subjected to colitis gravis." | 7.75 | [Effects of glutamine on the colon of mice subjected to colitis gravis]. ( Jia, HY; Li, JM; Li, S; Wang, JJ; Yu, Q, 2009) |
| "64 Kunming mice were divided randomly into 4 groups (n=16): healthy group: animals not subjected to colitis; model group: animals subjected to colitis gravis but without glutamine supplementation; low-Gln group: animals subjected to colitis gravis and with low dose of glutamine supplementation; high-Gln group: animals subjected to colitis gravis and with high dose of glutamine supplementation." | 7.75 | [Effects of glutamine on the colon of mice subjected to colitis gravis]. ( Jia, HY; Li, JM; Li, S; Wang, JJ; Yu, Q, 2009) |
| "The glutamine lessened the pathological injures in the colon and relieved the step up of the content of endotoxin in the blood serum , the step down level of counteracting oxidation and the step up activity of MPO in the colon tissue, which were caused by colitis gravis." | 7.75 | [Effects of glutamine on the colon of mice subjected to colitis gravis]. ( Jia, HY; Li, JM; Li, S; Wang, JJ; Yu, Q, 2009) |
| "The glutamine can protect the colon of mice subjected to colitis gravis." | 7.75 | [Effects of glutamine on the colon of mice subjected to colitis gravis]. ( Jia, HY; Li, JM; Li, S; Wang, JJ; Yu, Q, 2009) |
| "Colitis was induced by intrarectal administration of 2 mL, 4% acetic acid." | 5.91 | Neuroprotective effects of methyl jasmonate in male Wistar rats exposed to delayed acetic acid-induced ulcerative colitis: involvement of antioxidant status, GFAP, and IBA-1 immunoreactivities. ( Adedeji, TG; Aluko, OM; Ijomone, OM; Jeje, SO; Nathanniel, JN; Omayone, TP; Salami, FT, 2023) |
| "Colitis was evoked by a single transrectal injection of 1 ml of 4 % acetic acid." | 5.91 | Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia activity. ( Ahmed, KA; Elbaz, EM; Essam, RM; Safwat, MH, 2023) |
| "Ulcerative colitis is characterized as a chronic immune-mediated inflammatory condition, affecting the intestinal gastroenteric tissue." | 5.91 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "Experimental ulcerative colitis was induced in rats by intrarectal acetic acid administration." | 5.91 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "Mirabegron's ability to increase adiponectin in serum and decrease glutathione, GSTM1, and catalase in the colon may account for its protective effects." | 5.91 | Mirabegron alleviates acetic acid-induced colitis in rats: Role of adiponectin and GSTM1/GSH detoxification pathway. ( Abed El Baky, MF; Hafez, HM; Mohamed, MZ; Mokhemer, SA, 2023) |
| "Mirabegron is a selective beta-3 adrenergic receptor (β-3 AR) agonist used to treat an overactive bladder." | 5.91 | Mirabegron alleviates acetic acid-induced colitis in rats: Role of adiponectin and GSTM1/GSH detoxification pathway. ( Abed El Baky, MF; Hafez, HM; Mohamed, MZ; Mokhemer, SA, 2023) |
| "Ulcerative colitis is a chronic inflammation of the colon." | 5.91 | Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue. ( Amini-Khoei, H; AnjomShoa, M; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2023) |
| "To induce ulcerative colitis, animals received 0." | 5.91 | Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue. ( Amini-Khoei, H; AnjomShoa, M; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2023) |
| "The available ulcerative colitis drugs exhibit limited outcomes and adverse side effects." | 5.72 | Dual role of melatonin as an anti-colitis and anti-extra intestinal alterations against acetic acid-induced colitis model in rats. ( Ahmed, O; Elamir, A; Farid, A, 2022) |
| "major in rats with acetic acid-induced ulcerative colitis (UC)." | 5.72 | Evaluation of anti-inflammatory effects of leaf and seed extracts of Plantago major on acetic acid-induced ulcerative colitis in rats. ( Farid, A; Motevalian, M; Noori, M; Sheibani, M; Shojaii, A, 2022) |
| "Ulcerative colitis is an idiopathic disease that is widely incident worldwide." | 5.72 | Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis. ( Abdelhamid, AM; Amin, NA; Cavalu, S; El-Ahwany, E; El-Azez, RA; El-Rafi, AA; El-Sandarosy, R; Elagamy, HI; Essam, M; Essam, N; Gaafar, AGA; Girgis, S; Hasaballah, A; Kamal, I; Mahmoud, F; Mansour, M; Mohamed, D; Mohammed, OA; Nasr, M; Rizk, H; Saber, S; Youssef, ME, 2022) |
| "Pretreatment with molsidomine significantly reduced disease activity index, colon mass index, colonic macroscopic and histological damage." | 5.62 | Molsidomine alleviates acetic acid-induced colitis in rats by reducing oxidative stress, inflammation and apoptosis. ( El-Kashef, DH; Mohamed, NI; Suddek, GM, 2021) |
| "Curcumin has proven to be beneficial in the prevention and treatment of a number of inflammatory diseases, but due its poor bioavailability, the therapeutic applications are limited." | 5.56 | Anti-Ulcerative Effect of Curcumin-Galactomannoside Complex on Acetic Acid-Induced Experimental Model by Inhibiting Inflammation and Oxidative Stress. ( Asha, S; Girishkumar, B; Grace, J; Jose, SP; Krishnakumar, IM; Ratheesh, M; Sandya, S; Sheethal, S, 2020) |
| "The pathogenesis of ulcerative colitis (UC) is related to reduced antioxidant capacity and increased inflammatory processes." | 5.56 | Anti-Ulcerative Effect of Curcumin-Galactomannoside Complex on Acetic Acid-Induced Experimental Model by Inhibiting Inflammation and Oxidative Stress. ( Asha, S; Girishkumar, B; Grace, J; Jose, SP; Krishnakumar, IM; Ratheesh, M; Sandya, S; Sheethal, S, 2020) |
| "Experimentally ulcerative colitis (UC) was induced by AA in animals pretreated with three different doses of GS leaves extract (50, 100, 200 mg/kg/day) and a single dose of mesalazine (MES, 300 mg/kg/day) for seven days." | 5.40 | Pretreatment of Gymnema sylvestre revealed the protection against acetic acid-induced ulcerative colitis in rats. ( Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Aleisa, AM; Ola, MS; Parmar, MY, 2014) |
| "Ulcerative colitis is a chronic inflammatory disease and involves multiple etiological factors." | 5.39 | Protective effects of N-acetylcysteine on acetic acid-induced colitis in a porcine model. ( Chen, X; Ding, B; Hou, Y; Liu, Y; Long, M; Wang, L; Wang, Q; Wu, G; Yi, D, 2013) |
| " The study used the acetic acid model of colitis and thereafter delayed the healing process by the administration of indomethacin (Indo) (2 mg/kg, SC)." | 4.31 | Neuroprotective effects of methyl jasmonate in male Wistar rats exposed to delayed acetic acid-induced ulcerative colitis: involvement of antioxidant status, GFAP, and IBA-1 immunoreactivities. ( Adedeji, TG; Aluko, OM; Ijomone, OM; Jeje, SO; Nathanniel, JN; Omayone, TP; Salami, FT, 2023) |
| " On the eighth day, Rats received enemas containing a 4 % solution of acetic acid to induce colitis." | 4.31 | Imatinib mitigates experimentally-induced ulcerative colitis: Possible contribution of NF-kB/JAK2/STAT3/COX2 signaling pathway. ( Abdelaziz, RR; Ghoneim, HA; Shalaby, M; Suddek, GM, 2023) |
| " This study evaluated the anti-inflammatory effects of licofelone on acetic acid-induced colitis in rats." | 4.31 | Licofelone Attenuates Acetic Acid-Induced Colitis in Rats Through Suppression of the Inflammatory Mediators. ( Abdolghaffari, AH; Abdollahi, AR; Baeeri, M; Dehpour, AR; Khayatan, D; Lashgari, NA; Momtaz, S; Roudsari, NM; Shahraki, FN, 2023) |
| "Sprague Dawley rats were treated with oral 500 mg/kg sulphasalazine or 30, 100, and 300 mg/kg of PNE daily for 8 days with induction of colitis on the fourth day with acetic acid." | 4.31 | Acetic acid-induced colitis modulating potential of total crude alkaloidal extract of Picralima nitida seeds in rats. ( Boakye-Gyasi, E; Okyere, PD; Oppong-Kyekyeku, J; Osafo, N; Otu-Boakye, SA; Yeboah, KO, 2023) |
| "Experimental ulcerative colitis was induced in rats by intrarectal acetic acid administration." | 4.31 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "This study shows the therapeutic potential of topotecan in attenuating ulcerative colitis in rats probably via inhibition of the RORγT transcription factor and downstream mediators of Th-17 cells." | 4.31 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "In this study, the therapeutic effect of quinic acid (QA), which has anti-inflammatory activity, was investigated on acetic acid-induced colitis in male Wistar rats." | 4.31 | Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways. ( Amini-Khoei, H; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M; Sabzevary-Ghahfarokhi, M, 2023) |
| "Ulcerative colitis (UC) was induced in rats by acetic acid intrarectally, and the protective effects of QA in 10, 30, 60, and 100 mg/kg doses were investigated." | 4.31 | Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways. ( Amini-Khoei, H; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M; Sabzevary-Ghahfarokhi, M, 2023) |
| "To investigate the effect of givinostat treatment in acetic acid-induced ulcerative colitis model in rats." | 4.12 | Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model. ( Dibekoğlu, C; Erbaş, O, 2022) |
| " Rats were randomly divided into three equal groups, and colitis was induced on 20 rats by rectal administration of %4 solutions of acetic acid." | 4.12 | Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model. ( Dibekoğlu, C; Erbaş, O, 2022) |
| "Givinostat, a good protector and regenerator of tissue and an anti-inflammatory agent, may be involved in the treatment of colitis in the future." | 4.12 | Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model. ( Dibekoğlu, C; Erbaş, O, 2022) |
| " major in rats with acetic acid-induced ulcerative colitis (UC)." | 4.12 | Evaluation of anti-inflammatory effects of leaf and seed extracts of Plantago major on acetic acid-induced ulcerative colitis in rats. ( Farid, A; Motevalian, M; Noori, M; Sheibani, M; Shojaii, A, 2022) |
| " The effect of the extract in three additional in vivo models were studied: intestinal motility and diarrhea induced by ricin oil, and visceral pain induced by intracolonic administration of capsaicin." | 4.02 | Pharmacologycal activity of peperina (Minthostachys verticillata) on gastrointestinal tract. ( Bach, H; Carranza, A; Gorzalczany, SB; Rodríguez Basso, A; Zainutti, VM, 2021) |
| "CL improved body weight gain, mean macroscopic and microscopic ulcer scores in the colon of rats suffering from acetic acid-induced IBD." | 3.83 | Effect of turmeric on colon histology, body weight, ulcer, IL-23, MPO and glutathione in acetic-acid-induced inflammatory bowel disease in rats. ( Adeghate, E; Al Ahmed, MM; Al Zaabi, A; Amir, N; Bastaki, SMA, 2016) |
| " Present study is designed to evaluate the preventative activities of GS against acetic acid (AA)-induced ulcerative colitis in Wistar rats." | 3.80 | Pretreatment of Gymnema sylvestre revealed the protection against acetic acid-induced ulcerative colitis in rats. ( Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Aleisa, AM; Ola, MS; Parmar, MY, 2014) |
| "The administration of acetic acid induced acute rat UC, as indicated by diarrhea, weight loss, and colonic mucosal damage." | 3.79 | Protective effects of hydrogen-rich saline on ulcerative colitis rat model. ( He, J; Mei, X; Sun, A; Sun, X; Wang, J; Wang, Q; Xiong, S; Zhang, C; Zhang, J, 2013) |
| " 2) Mice with xylene-induced acute exudative edema and acetic acid-induced writhing." | 3.77 | Evidence for the complementary and synergistic effects of the three-alkaloid combination regimen containing berberine, hypaconitine and skimmianine on the ulcerative colitis rats induced by trinitrobenzene-sulfonic acid. ( Guo, Z; Li, C; Li, Q; Li, Y; Liu, L; Long, Y; Mei, Q; Niu, Y; Sun, Y; Wang, Y; Wu, H; Zhang, M, 2011) |
| "To investigate the effects of glutamine on the colonic mucosa of mice subjected to colitis gravis." | 3.75 | [Effects of glutamine on the colon of mice subjected to colitis gravis]. ( Jia, HY; Li, JM; Li, S; Wang, JJ; Yu, Q, 2009) |
| "64 Kunming mice were divided randomly into 4 groups (n=16): healthy group: animals not subjected to colitis; model group: animals subjected to colitis gravis but without glutamine supplementation; low-Gln group: animals subjected to colitis gravis and with low dose of glutamine supplementation; high-Gln group: animals subjected to colitis gravis and with high dose of glutamine supplementation." | 3.75 | [Effects of glutamine on the colon of mice subjected to colitis gravis]. ( Jia, HY; Li, JM; Li, S; Wang, JJ; Yu, Q, 2009) |
| "The glutamine lessened the pathological injures in the colon and relieved the step up of the content of endotoxin in the blood serum , the step down level of counteracting oxidation and the step up activity of MPO in the colon tissue, which were caused by colitis gravis." | 3.75 | [Effects of glutamine on the colon of mice subjected to colitis gravis]. ( Jia, HY; Li, JM; Li, S; Wang, JJ; Yu, Q, 2009) |
| "The glutamine can protect the colon of mice subjected to colitis gravis." | 3.75 | [Effects of glutamine on the colon of mice subjected to colitis gravis]. ( Jia, HY; Li, JM; Li, S; Wang, JJ; Yu, Q, 2009) |
| "Amplified chemiluminescence was used to measure reactive oxygen species production by colonic biopsy specimens from rats with acetic acid induced colitis and to assess the in vitro effect of conventional antioxidants, standard therapies and proposed novel therapies for inflammatory bowel disease." | 3.69 | Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis. ( Blades, S; Blake, DR; Chander, CL; Claxson, AW; Coumbe, A; Millar, AD; Morris, CJ; Panetta, J; Rampton, DS, 1996) |
| "The model was validated by demonstrating that the profile of effects on chemiluminescence of acetic acid induced colitis biopsy specimens given by conventional antioxidants (sodium azide, catalase, copper-zinc superoxide dismutase, dimethyl sulphoxide, N-acetylcysteine and ascorbate) and standard therapies (5-aminosalicylate and hydrocortisone) resembled that previously reported using biopsy specimens from ulcerative colitis." | 3.69 | Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis. ( Blades, S; Blake, DR; Chander, CL; Claxson, AW; Coumbe, A; Millar, AD; Morris, CJ; Panetta, J; Rampton, DS, 1996) |
| "The similarity of the chemiluminescence responses of colonic biopsy specimens from acetic acid induced colitis and ulcerative colitis to a range of conventional antioxidants and standard treatments suggests that this model is a useful method for testing the antioxidant potential of new therapies for inflammatory bowel disease." | 3.69 | Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis. ( Blades, S; Blake, DR; Chander, CL; Claxson, AW; Coumbe, A; Millar, AD; Morris, CJ; Panetta, J; Rampton, DS, 1996) |
| "Changes in the colonic mucosa-associated microflora were determined both in patients with active and inactive ulcerative colitis and in rats with acetic acid-induced colitis." | 3.68 | Impairment of bacterial flora in human ulcerative colitis and experimental colitis in the rat. ( Andersson, R; Ar'Rajab, A; Bengmark, S; Fabia, R; Jeppsson, B; Johansson, ML; Molin, G; Willén, R, 1993) |
| " The objective of this study was to define the role of neutrophils in the colonic hyperemia associated with acetic acid-induced colitis in rats." | 3.67 | Inflammation-induced intestinal hyperemia in the rat: role of neutrophils. ( Deitch, EA; Granger, DN; Grisham, MB; Li, MA; Sekizuka, E, 1988) |
| "Ulcerative colitis (UC) and Crohn's disease (CD) are two major forms of inflammatory bowel disease (IBD)." | 1.91 | Dark-purple rice extract modulates gut microbiota composition in acetic acid- and indomethacin-induced inflammatory bowel disease in rats. ( Gruneck, L; Phunikhom, K; Popluechai, S; Sattayasai, J; Sharpton, TJ; Thipart, K, 2023) |
| "Colitis was induced by intrarectal administration of 2 mL, 4% acetic acid." | 1.91 | Neuroprotective effects of methyl jasmonate in male Wistar rats exposed to delayed acetic acid-induced ulcerative colitis: involvement of antioxidant status, GFAP, and IBA-1 immunoreactivities. ( Adedeji, TG; Aluko, OM; Ijomone, OM; Jeje, SO; Nathanniel, JN; Omayone, TP; Salami, FT, 2023) |
| "Colitis was evoked by a single transrectal injection of 1 ml of 4 % acetic acid." | 1.91 | Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia activity. ( Ahmed, KA; Elbaz, EM; Essam, RM; Safwat, MH, 2023) |
| "Lycopene (LYC) is a powerful antioxidant with strong free radical scavenging property." | 1.91 | The possible effect of lycopene in ameliorating experimentally induced ulcerative colitis in adult male albino rats (A histological, immunohistochemical, and ultrastructural study). ( El-Ghazouly, DE; Kashef, SM; Yassien, RI, 2023) |
| "Acetic acid (AA) was instilled intrarectally in groups (II-IV)." | 1.91 | Ezetimibe alleviates acetic acid-induced ulcerative colitis in rats: targeting the Akt/NF-κB/STAT3/CXCL10 signaling axis. ( Abdel-Rahman, RF; Mostafa, RE, 2023) |
| "Ezetimibe treatment significantly ameliorated all the aforementioned parameters." | 1.91 | Ezetimibe alleviates acetic acid-induced ulcerative colitis in rats: targeting the Akt/NF-κB/STAT3/CXCL10 signaling axis. ( Abdel-Rahman, RF; Mostafa, RE, 2023) |
| "Ezetimibe treatment mitigates UC via downregulation of the Akt/NF-κB/STAT3/CXCL10 signaling axis." | 1.91 | Ezetimibe alleviates acetic acid-induced ulcerative colitis in rats: targeting the Akt/NF-κB/STAT3/CXCL10 signaling axis. ( Abdel-Rahman, RF; Mostafa, RE, 2023) |
| "Ezetimibe is a cholesterol-lowering drug having anti-inflammatory and pleiotropic properties." | 1.91 | Ezetimibe alleviates acetic acid-induced ulcerative colitis in rats: targeting the Akt/NF-κB/STAT3/CXCL10 signaling axis. ( Abdel-Rahman, RF; Mostafa, RE, 2023) |
| "Ulcerative colitis is an inflammatory condition with ulcerations throughout the colon." | 1.91 | Design and characterization of dexamethasone loaded microsponges for the management of ulcerative colitis. ( Baranauskaite, J; Özdemir, S; Sümer, E; Üner, B; Yaba, A; Yıldırım, E, 2023) |
| "Ulcerative colitis is characterized as a chronic immune-mediated inflammatory condition, affecting the intestinal gastroenteric tissue." | 1.91 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "Experimental ulcerative colitis was induced in rats by intrarectal acetic acid administration." | 1.91 | Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor. ( Bhatt, LK; Parihar, N, 2023) |
| "Mirabegron's ability to increase adiponectin in serum and decrease glutathione, GSTM1, and catalase in the colon may account for its protective effects." | 1.91 | Mirabegron alleviates acetic acid-induced colitis in rats: Role of adiponectin and GSTM1/GSH detoxification pathway. ( Abed El Baky, MF; Hafez, HM; Mohamed, MZ; Mokhemer, SA, 2023) |
| "Mirabegron is a selective beta-3 adrenergic receptor (β-3 AR) agonist used to treat an overactive bladder." | 1.91 | Mirabegron alleviates acetic acid-induced colitis in rats: Role of adiponectin and GSTM1/GSH detoxification pathway. ( Abed El Baky, MF; Hafez, HM; Mohamed, MZ; Mokhemer, SA, 2023) |
| "Ulcerative colitis is a chronic inflammation of the colon." | 1.91 | Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue. ( Amini-Khoei, H; AnjomShoa, M; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2023) |
| "To induce ulcerative colitis, animals received 0." | 1.91 | Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue. ( Amini-Khoei, H; AnjomShoa, M; Ghasemi-Dehnoo, M; Lorigooini, Z; Rafieian-Kopaei, M, 2023) |
| "pharnaceoides crude extract in the treatment of ulcerative colitis and might be a promising remedy to manage inflammatory disorders." | 1.72 | Gisekia pharnaceoides Restores Colonic Mucosal Homeostasis by Regulating Antioxidant Enzyme System and Cytokines Signaling in Ulcerative Colitis Mice Model. ( Arshad, HM; Aslam, N; Awan, AM; Jabeen, Q; Javaid, F; Majeed, W, 2022) |
| "pharnaceoides in acetic acid-induced ulcerative colitis in mice and to discover the mechanism for anti-inflammatory action." | 1.72 | Gisekia pharnaceoides Restores Colonic Mucosal Homeostasis by Regulating Antioxidant Enzyme System and Cytokines Signaling in Ulcerative Colitis Mice Model. ( Arshad, HM; Aslam, N; Awan, AM; Jabeen, Q; Javaid, F; Majeed, W, 2022) |
| "In acetic acid-induced ulcerative colitis model, Gp." | 1.72 | Gisekia pharnaceoides Restores Colonic Mucosal Homeostasis by Regulating Antioxidant Enzyme System and Cytokines Signaling in Ulcerative Colitis Mice Model. ( Arshad, HM; Aslam, N; Awan, AM; Jabeen, Q; Javaid, F; Majeed, W, 2022) |
| "Phenytoin was administered in two doses during the treatment." | 1.72 | Topical phenytoin administration accelerates the healing of acetic acid-induced colitis in rats: evaluation of transforming growth factor-beta, platelet-derived growth factor, and vascular endothelial growth factor. ( Abdolahi, A; Fattahi, N; Goudarzzadeh, S; Hassanzadeh, K; Izadpanah, E; Manoochehri, F; Moloudi, MR; Nikkhoo, B; Vahabzadeh, Z, 2022) |
| "The available ulcerative colitis drugs exhibit limited outcomes and adverse side effects." | 1.72 | Dual role of melatonin as an anti-colitis and anti-extra intestinal alterations against acetic acid-induced colitis model in rats. ( Ahmed, O; Elamir, A; Farid, A, 2022) |
| "major in rats with acetic acid-induced ulcerative colitis (UC)." | 1.72 | Evaluation of anti-inflammatory effects of leaf and seed extracts of Plantago major on acetic acid-induced ulcerative colitis in rats. ( Farid, A; Motevalian, M; Noori, M; Sheibani, M; Shojaii, A, 2022) |
| "Ulcerative colitis is an idiopathic disease that is widely incident worldwide." | 1.72 | Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis. ( Abdelhamid, AM; Amin, NA; Cavalu, S; El-Ahwany, E; El-Azez, RA; El-Rafi, AA; El-Sandarosy, R; Elagamy, HI; Essam, M; Essam, N; Gaafar, AGA; Girgis, S; Hasaballah, A; Kamal, I; Mahmoud, F; Mansour, M; Mohamed, D; Mohammed, OA; Nasr, M; Rizk, H; Saber, S; Youssef, ME, 2022) |
| "Curcumin's role in the treatment of ulcerative colitis (UC) has been proven by numerous studies, but its preventive administration, with the aim of reducing the remission episodes that are characteristic of this disease, must be further investigated." | 1.72 | Curcumin-Loaded Microspheres Are Effective in Preventing Oxidative Stress and Intestinal Inflammatory Abnormalities in Experimental Ulcerative Colitis in Rats. ( Hales, D; Kiss, B; Muntean, DM; Neag, MA; Porfire, A; Rațiu, IA; Sesărman, A; Ștefan, MG; Tefas, LR; Tomuță, I, 2022) |
| "Acetic acid (AA) was used for UC induction, and sulfasalazine (SLZ) was used as a positive control." | 1.62 | Protective effect of mirtazapine against acetic acid-induced ulcerative colitis in rats: Role of NLRP3 inflammasome pathway. ( Abdel-Gaber, SA; Gad, AA; Hafez, HM; Ibrahim, MA; Mohammed Naguib Abdel Hafez, S; Yehia Abdelzaher, W, 2021) |
| "Mirtazapine (MRT) is a well-known antidepressant that was proven to have anti-inflammatory activity; however, to date, its role has not been investigated in UC." | 1.62 | Protective effect of mirtazapine against acetic acid-induced ulcerative colitis in rats: Role of NLRP3 inflammasome pathway. ( Abdel-Gaber, SA; Gad, AA; Hafez, HM; Ibrahim, MA; Mohammed Naguib Abdel Hafez, S; Yehia Abdelzaher, W, 2021) |
| "Pirfenidone was administered to rats in different experimental groups (125 or 250 and 500 mg/kg, orally) for two weeks." | 1.62 | A novel role of pirfenidone in attenuation acetic acid induced ulcerative colitis by modulation of TGF-β1 / JNK1 pathway. ( Antar, SA; Kh ElMahdy, M; Khodir, AE, 2021) |
| "Sulfasalazine and JLC were administrated orally and initialized 6 h after TNBS enema, once a day for seven consecutive days." | 1.62 | Jiaolong capsule protects SD rats against 2,4,6-trinitrobenzene sulfonic acid induced colitis. ( Chen, G; Diao, F; Dong, M; Li, Y; Lin, W; Liu, T; Liu, Y; Mei, Q; Ruan, Y; Sun, Y; Tang, T; Zhou, H, 2021) |
| "Ulcerative colitis is a gut inflammatory disorder due to altered immune response to gut microbiome, with interplay of environmental and genetic factors." | 1.62 | Protective effect of 6-paradol in acetic acid-induced ulcerative colitis in rats. ( Abdallah, HM; El-Halawany, AM; Murad, HAS; Rafeeq, M, 2021) |
| "Using 2,4-dinitrochlorobenzene combined with acetic acid to induce chronic ulcerative colitis (chronic UC) in rats." | 1.62 | Study on the effect of the treatment of Periplaneta americana L. extract Ento-B by Dinitrochlorobenzene combined with acetic acid induced UC in rats. ( He, M; Hilola, A; Liu, H; Liu, SS; Xu, YS; Zhang, CG; Zhou, N, 2021) |
| "Ulcerative colitis is a form of inflammatory bowel disease that is characterized by acute and chronic inflammation." | 1.62 | Effects of hydro-ethanolic extract of leaves of Maesa lanceolata (Mursinaceae) on acetic acid-induced ulcerative colitis in rats. ( Fokam Tagne, MA; Kamgang, R; Kom, B; Mazo, AG; Ngakou Mukam, J; Noubissi, PA; Sokeng Dongmo, S; Tchoffo, A, 2021) |
| "Pretreatment with molsidomine significantly reduced disease activity index, colon mass index, colonic macroscopic and histological damage." | 1.62 | Molsidomine alleviates acetic acid-induced colitis in rats by reducing oxidative stress, inflammation and apoptosis. ( El-Kashef, DH; Mohamed, NI; Suddek, GM, 2021) |
| "domestica on ulcerative colitis induced by acetic acid in rats." | 1.56 | Effect of Sorbus domestica and its active constituents in an experimental model of colitis rats induced by acetic acid. ( Gürağaç Dereli, FT; Khan, H; Küpeli Akkol, E; Sobarzo-Sánchez, E; Taştan, H, 2020) |
| "Genistein is a major isoflavone with antioxidant and anti-inflammatory activities and hydrophobic features." | 1.56 | Protection by pure and genistein fortified extra virgin olive oil, canola oil, and rice bran oil against acetic acid-induced ulcerative colitis in rats. ( Amanat, S; Firoozi, D; Iraji, A; Koohi-Hosseinabadi, O; Noorafshan, A; Sadeghi, F; Tanideh, N, 2020) |
| "Ulcerative Colitis is a universal autoimmune disease with high incidence rates worldwide." | 1.56 | Gliclazide attenuates acetic acid-induced colitis via the modulation of PPARγ, NF-κB and MAPK signaling pathways. ( Arafa, EA; Mohamed, WR; Omar, HA; Zaher, DM, 2020) |
| "However, its impact on ulcerative colitis has never been investigated." | 1.56 | Gliclazide attenuates acetic acid-induced colitis via the modulation of PPARγ, NF-κB and MAPK signaling pathways. ( Arafa, EA; Mohamed, WR; Omar, HA; Zaher, DM, 2020) |
| "Curcumin has proven to be beneficial in the prevention and treatment of a number of inflammatory diseases, but due its poor bioavailability, the therapeutic applications are limited." | 1.56 | Anti-Ulcerative Effect of Curcumin-Galactomannoside Complex on Acetic Acid-Induced Experimental Model by Inhibiting Inflammation and Oxidative Stress. ( Asha, S; Girishkumar, B; Grace, J; Jose, SP; Krishnakumar, IM; Ratheesh, M; Sandya, S; Sheethal, S, 2020) |
| "The pathogenesis of ulcerative colitis (UC) is related to reduced antioxidant capacity and increased inflammatory processes." | 1.56 | Anti-Ulcerative Effect of Curcumin-Galactomannoside Complex on Acetic Acid-Induced Experimental Model by Inhibiting Inflammation and Oxidative Stress. ( Asha, S; Girishkumar, B; Grace, J; Jose, SP; Krishnakumar, IM; Ratheesh, M; Sandya, S; Sheethal, S, 2020) |
| "Nifuroxazide is an oral nitrofuran antibiotic used as antidiarrheal medication." | 1.56 | The interplay of the inhibitory effect of nifuroxazide on NF-κB/STAT3 signaling attenuates acetic acid-induced ulcerative colitis in rats. ( El-Far, YM; El-Shafey, M; Elsherbiny, NM; Said, E, 2020) |
| "Background Ulcerative colitis is a chronic mucosal inflammation of the large intestine mainly affecting the colon and rectum." | 1.51 | Exploring the therapeutic potential of sodium benzoate in acetic acid-induced ulcerative colitis in rats. ( Bali, A; Jaggi, AS; Kaur, G; Walia, D, 2019) |
| "Ulcerative colitis is a chronic inflammatory disorder characterized by oxidative stress and upregulation of proinflammatory mediators in colonic tissue." | 1.51 | Febuxostat attenuates ulcerative colitis by the inhibition of NF-κB, proinflammatory cytokines, and oxidative stress in mice. ( Amirshahrokhi, K, 2019) |
| "Methadone was injected subcutaneously (s." | 1.48 | Involvement of central opioid receptors in protective effects of methadone on experimental colitis in rats. ( Dehpour, AR; Fakhraei, N; Hashemizadeh, S; Javadian, N; Nili, F; Rahimi, N; Rahimian, R, 2018) |
| "Ulcerative colitis was induced by intrarectal administration of acetic acid 4%." | 1.48 | Involvement of central opioid receptors in protective effects of methadone on experimental colitis in rats. ( Dehpour, AR; Fakhraei, N; Hashemizadeh, S; Javadian, N; Nili, F; Rahimi, N; Rahimian, R, 2018) |
| "Theophylline treatment also reduced MPO activity and tumor necrosis factor-α (TNF-α), interleukin 1β (IL-1 β) and interleukin 6 (IL-6) concentrations in inflamed colon." | 1.46 | The effect of theophylline on acetic acid induced ulcerative colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "Treatment with theophylline at the doses of 20 and 50mg/kg attenuated acetic acid induced ulcerative colitis as shown by improvement in body weight loss, macroscopic score, ulcer area, hematocrit and histopathological score." | 1.46 | The effect of theophylline on acetic acid induced ulcerative colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "Theophylline has a protective effect in acetic acid-induced ulcerative colitis which might be due to its anti-inflammatory activities." | 1.46 | The effect of theophylline on acetic acid induced ulcerative colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "Ulcerative colitis is a relapsing inflammatory disorder of the colon." | 1.46 | The effect of theophylline on acetic acid induced ulcerative colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "However, the effect of theophylline on ulcerative colitis has not yet been investigated." | 1.46 | The effect of theophylline on acetic acid induced ulcerative colitis in rats. ( Ghasemi-Pirbaluti, M; Hosseini, MJ; Motaghi, E; Najafi, A, 2017) |
| "Ulcerative colitis is majorly associated with oxidative stress and inflammation in colon tissue leading to damage." | 1.46 | Protective effect of Averrhoa bilimbi L. fruit extract on ulcerative colitis in wistar rats via regulation of inflammatory mediators and cytokines. ( Berlin Grace, VM; Guruvayoorappan, C; Sakthivel, KM; Suluvoy, JK, 2017) |
| "Both treatment doses of bevacizumab were observed to have a protective effect in an experimental colitis model, and the dosage of 2." | 1.46 | Effect of bevacizumab on acetic acid-induced ulcerative colitis in rats. ( Benli, I; Daldal, E; Demir, E; Gevrek, F; Ozsoy, S; Ozsoy, Z; Yenidogan, E, 2017) |
| "Azathioprine is a highly efficient immunosuppressant drug used for treatment of inflammatory bowel disease (IBD)." | 1.46 | Development and in vivo evaluation of chitosan beads for the colonic delivery of azathioprine for treatment of inflammatory bowel disease. ( Elsabahy, M; Helmy, AM; Ibrahim, EA; Mahmoud, MA; Soliman, GM, 2017) |
| "Cardamonin is a natural chalcone derivative with considerable anti-inflammatory activity." | 1.46 | Protective effect of cardamonin against acetic acid-induced ulcerative colitis in rats. ( Abd Al Haleem, EN; Ali, AA; Khaleel, SA; Sallam, AS, 2017) |
| "Cardamonin has a protective effect against acetic acid-induced colitis." | 1.46 | Protective effect of cardamonin against acetic acid-induced ulcerative colitis in rats. ( Abd Al Haleem, EN; Ali, AA; Khaleel, SA; Sallam, AS, 2017) |
| "PAE can protect against ulcerative colitis and this protection is attributed to anti-inflammation and fibroblasts viability." | 1.43 | Protective effect of Periplaneta americana extract in ulcerative colitis rats induced by dinitrochlorobenzene and acetic acid. ( Chen, J; Huang, L; Jin, J; Li, N; Lu, R; Lu, Y; Yu, Y; Zhang, L, 2016) |
| "Acetic acid ulcerative colitis (UC) is an experimental condition created due to intra-rectal administration of acetic acid which causes inflammation and ulceration in the lining of colon and rectum." | 1.42 | Mesalazine-probiotics beads for acetic acid experimental colitis: formulation and characterization of a promising new therapeutic strategy for ulcerative colitis. ( Bansal, D; Dubey, N; Ganeshpurkar, A; Pandey, V; Vishwakarma, N, 2015) |
| "Treatment with embelin LNs decreased MPO, LDH and LPO levels, increased reduced GSH levels which indicated better treatment of ulcerative colitis was achieved." | 1.42 | Embelin lipid nanospheres for enhanced treatment of ulcerative colitis - Preparation, characterization and in vivo evaluation. ( Badamaranahalli, SS; Bhagawati, ST; Durg, S; Kopparam, M, 2015) |
| "Embelin LNs were developed using soya bean oil/virgin coconut oil as liquid lipid carrier and soya/egg lecithin as stabilizer by hot homogenization followed by ultrasonication technique." | 1.42 | Embelin lipid nanospheres for enhanced treatment of ulcerative colitis - Preparation, characterization and in vivo evaluation. ( Badamaranahalli, SS; Bhagawati, ST; Durg, S; Kopparam, M, 2015) |
| "Ulcerative colitis is an inflammatory disorder characterized by neutrophils infiltration, oxidative stress, upregulation of pro-inflammatory mediators and cytokines." | 1.42 | Protective effect of cavidine on acetic acid-induced murine colitis via regulating antioxidant, cytokine profile and NF-κB signal transduction pathways. ( He, Z; Li, W; Mu, Q; Niu, X; Wang, X; Wang, Y; Yao, H; Zhang, H, 2015) |
| "Induction of ulcerative colitis in rats was performed by intra-rectal acetic acid (5% v/v) administration for 3 consecutive days." | 1.42 | Co-administration of α-lipoic acid and cyclosporine aggravates colon ulceration of acetic acid-induced ulcerative colitis via facilitation of NO/COX-2/miR-210 cascade. ( Abdel-Galil, AG; El-Gowelli, HM; Ibrahim, ER; Saad, EI, 2015) |
| "Experimentally ulcerative colitis (UC) was induced by AA in animals pretreated with three different doses of GS leaves extract (50, 100, 200 mg/kg/day) and a single dose of mesalazine (MES, 300 mg/kg/day) for seven days." | 1.40 | Pretreatment of Gymnema sylvestre revealed the protection against acetic acid-induced ulcerative colitis in rats. ( Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Aleisa, AM; Ola, MS; Parmar, MY, 2014) |
| "An acetic acid (AA)-induced ulcerative colitis rat model was applied in the study." | 1.40 | The in vivo and in vitro study of polysaccharides from a two-herb formula on ulcerative colitis and potential mechanism of action. ( Jia, W; Lu, H; Ma, C; Qiu, M; Sun, W; Wu, H; Xin, X; Yang, Y; Zhao, A; Zhao, L; Zou, H, 2014) |
| "Acetic acid was given via a rectal route to induce acute colitis in rats." | 1.40 | The protective effect of Echinacea spp. (Echinacea angustifolia and Echinacea purpurea) in a rat colitis model induced by acetic acid. ( Can, M; Dogan, Z; Ergul, B; Filik, L; Gonultaş, MA; Hucumenoglu, S; Sarikaya, M, 2014) |
| "Curcumin treatment was associated with amelioration of macroscopic and microscopic colitis sores, decreased MPO activity, and decreased MDA levels in acetic acid-induced colitis." | 1.39 | Effects of curcumin on apoptosis and oxidoinflammatory regulation in a rat model of acetic acid-induced colitis: the roles of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase. ( Akpolat, M; Cerkezkayabekir, A; Kizilay, G; Omurlu, IK; Sapmaz-Metin, M; Topcu-Tarladacalisir, Y; Uz, YH, 2013) |
| "The hydrogen treatment was performed once every 2 d and lasted 2 wk." | 1.39 | Protective effects of hydrogen-rich saline on ulcerative colitis rat model. ( He, J; Mei, X; Sun, A; Sun, X; Wang, J; Wang, Q; Xiong, S; Zhang, C; Zhang, J, 2013) |
| "Treatment with hydrogen-rich saline reduced the weight loss and diarrhea and alleviated the colonic mucosal damage in the UC rats." | 1.39 | Protective effects of hydrogen-rich saline on ulcerative colitis rat model. ( He, J; Mei, X; Sun, A; Sun, X; Wang, J; Wang, Q; Xiong, S; Zhang, C; Zhang, J, 2013) |
| "Hydrogen was supplied through intraperitoneal injection of 10 or 20 mL/kg hydrogen-rich saline." | 1.39 | Protective effects of hydrogen-rich saline on ulcerative colitis rat model. ( He, J; Mei, X; Sun, A; Sun, X; Wang, J; Wang, Q; Xiong, S; Zhang, C; Zhang, J, 2013) |
| "Ulcerative colitis is a chronic inflammatory disease and involves multiple etiological factors." | 1.39 | Protective effects of N-acetylcysteine on acetic acid-induced colitis in a porcine model. ( Chen, X; Ding, B; Hou, Y; Liu, Y; Long, M; Wang, L; Wang, Q; Wu, G; Yi, D, 2013) |
| "amentoflavone was also able to inhibit the activation and translocation of transcription factors, nuclear factor (NF)-κB subunits (p65/p50)." | 1.39 | Amentoflavone inhibits iNOS, COX-2 expression and modulates cytokine profile, NF-κB signal transduction pathways in rats with ulcerative colitis. ( Guruvayoorappan, C; Sakthivel, KM, 2013) |
| "Ulcerative colitis is a chronic inflammatory disorder characterized by oxidative stress, leucocyte infiltration and upregulation of pro-inflammatory cytokines." | 1.39 | Amentoflavone inhibits iNOS, COX-2 expression and modulates cytokine profile, NF-κB signal transduction pathways in rats with ulcerative colitis. ( Guruvayoorappan, C; Sakthivel, KM, 2013) |
| "Melatonin is a powerful antioxidant and a scavenger of hydroxyl radicals." | 1.37 | Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats. ( Aktolga, S; Cetinkaya, A; Dorko, K; Gramignoli, R; Marongiu, F; Tahan, G; Tahan, V, 2011) |
| "Melatonin has also been shown to have anti-inflammatory activities in tissues." | 1.37 | Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats. ( Aktolga, S; Cetinkaya, A; Dorko, K; Gramignoli, R; Marongiu, F; Tahan, G; Tahan, V, 2011) |
| "Embelin treatment significantly decreased clinical activity score, gross lesion score, percent affected area and wet colon weight when compared to acetic acid induced controls." | 1.37 | Protective effect of embelin against acetic acid induced ulcerative colitis in rats. ( Badami, S; Biradar, MI; Mahendran, S; Raj, P; Srivastava, K; Thippeswamy, BS; Veerapur, VP, 2011) |
| "Development of ulcerative colitis was accompanied by the activation of iNOS/COX-2/5-LOX and increased contents of nitric oxide (NO), prostaglandin E₂ (PGE₂), and leukotriene B₄ (LTB₄)." | 1.37 | Role of nitric oxide-synthase and cyclooxygenase/lipooxygenase systems in development of experimental ulcerative colitis. ( Fomenko, IS; Panasyuk, NB; Sklyarov, AY, 2011) |
| "Acetic acid was given to 2 groups of animals to induce colitis while the other 2 groups received saline intrarectally." | 1.37 | Vitamin E has a dual effect of anti-inflammatory and antioxidant activities in acetic acid-induced ulcerative colitis in rats. ( Aydin, S; Aytac, E; Aytekin, H; Dogusoy, G; Gunduz, F; Tahan, G; Tahan, V; Uzun, H, 2011) |
| "Ulcerative colitis is a chronically recurrent inflammatory bowel disease of unknown origin." | 1.34 | Ameliorative effect of pyrrolidinedithiocarbamate on acetic acid-induced colitis in rats. ( Arafa, M; El-Eter, E; El-Medany, A; Hagar, HH, 2007) |
| "In Crohn's disease more than in ulcerative colitis, the aggregates had a predominant basal or transmural distribution." | 1.33 | Morphology of colorectal lymphoid aggregates in cancer, diverticular and inflammatory bowel diseases. ( Di Betta, E; Di Fabio, F; Fisogni, S; Mariani, P; Nascimbeni, R; Villanacci, V, 2005) |
| "A total of 77 patients (41 colorectal cancer, 27 diverticular disease, six ulcerative colitis, three Crohn's disease) undergoing colorectal resection were included." | 1.33 | Morphology of colorectal lymphoid aggregates in cancer, diverticular and inflammatory bowel diseases. ( Di Betta, E; Di Fabio, F; Fisogni, S; Mariani, P; Nascimbeni, R; Villanacci, V, 2005) |
| "Ulcerative colitis is associated with altered contractile activity and transit time of colon." | 1.33 | Proglumide attenuates experimental colitis in rats. ( Al Moutaery, A, 2005) |
| " Administration of either azithromycin or erythromycin at different dosage (10, 20 and 40 mg/kg orally, daily for 5 consecutive days) significantly (P < 0." | 1.33 | Azithromycin and erythromycin ameliorate the extent of colonic damage induced by acetic acid in rats. ( Arafah, M; El-Medany, A; Mahgoub, A; Moursi, M; Mustafa, A, 2005) |
| "Ulcerative colitis is a common inflammatory bowel disease (IBD) of unknown etiology." | 1.33 | Azithromycin and erythromycin ameliorate the extent of colonic damage induced by acetic acid in rats. ( Arafah, M; El-Medany, A; Mahgoub, A; Moursi, M; Mustafa, A, 2005) |
| "The efficacy of various drugs used to treat ulcerative colitis (UC) was investigated." | 1.33 | Ginkgo biloba attenuates mucosal damage in a rat model of ulcerative colitis. ( El-Medany, A; El-Medany, G; Hagar, HH; Mustafa, A, 2006) |
| "Ulcerative colitis was induced in rats by intracolonic injection of 2 mL of 7% acetic acid." | 1.33 | [Intestinal mucosa protection of muscovite n ulcerative colitis in rats]. ( Chen, SJ; Si, JM; Wang, LJ, 2005) |
| "Patients with chronic ulcerative colitis have a significantly increased risk of colorectal cancer development." | 1.33 | Chronic colitis promotes tumor development. ( Nagawa, H; Sato, H; Shinozaki, M; Watanabe, T, 2006) |
| "Then the 50 models of ulcerative colitis were randomly assigned into 3 groups: model + placebo group (n = 20, infused intragastrically with normal saline 2 ml/d for 7 days), model + pravastatin group (n = 15, infused intragastrically with pravastatin 1 mg x kg(-1) x d(-1)), and model + salicylazosulfapyridium (SASP) group (n = 15, infused intragastrically with SASP 0." | 1.33 | [Therapeutic effects of pravastatin on colitis induced by acetic acid and relevant mechanism: experiment with rats]. ( Chen, C; Ran, ZH; Xiao, SD, 2006) |
| "However, its effects on ulcerative colitis have not been investigated." | 1.32 | Effect of hyperbaric oxygen on experimental acute distal colitis. ( Akay, C; Deveci, S; Gulec, B; Oter, S; Sen, D; Yasar, M; Yildiz, S, 2004) |
| "We have developed a new experimental ulcerative colitis model in rats." | 1.31 | [The new experimental ulcerative colitis model in rats induced by subserosal injection of acetic acid]. ( Hamamoto, S; Iwadate, K; Kojima, R; Moriwaki, M; Ohwaki, T, 2001) |
| "The mechanism of tissue damage in ulcerative colitis (UC) is unknown." | 1.31 | Novel antioxidants zolimid and AEOL11201 ameliorate colitis in rats. ( Banan, A; Bocckino, S; Choudhary, S; Day, BJ; Keshavarzian, A; Wade, M; Yong, S, 2001) |
| "Ulcerative colitis is characterized by dysfunctional motility." | 1.31 | Studies on the expression and function of beta-3-adrenoceptors in the colon of rats with acetic acid-induced colitis. ( Hussein, SM; Khan, I; Oriowo, M, 2002) |
| "Ulcerative colitis was associated with significantly elevated levels of myeloperoxidase activity in the colon segments." | 1.31 | Studies on the expression and function of beta-3-adrenoceptors in the colon of rats with acetic acid-induced colitis. ( Hussein, SM; Khan, I; Oriowo, M, 2002) |
| "Acetic acid-induced ulcerative colitis in rats was not associated with changes in the expression and/or function of beta(3)-adrenoceptors in the rat colon." | 1.31 | Studies on the expression and function of beta-3-adrenoceptors in the colon of rats with acetic acid-induced colitis. ( Hussein, SM; Khan, I; Oriowo, M, 2002) |
| "In patients with active ulcerative colitis, significant decreases in the number of anaerobic bacteria (Brain Heart Infusion medium), anaerobic gram-negatives and Lactobacillus were found, whereas no changes were seen in the number of aerobic bacteria and Enterobacteriaceae." | 1.29 | Impairment of bacterial flora in human ulcerative colitis and experimental colitis in the rat. ( Andersson, R; Ar'Rajab, A; Bengmark, S; Fabia, R; Jeppsson, B; Johansson, ML; Molin, G; Willén, R, 1993) |
| " Our data suggest that both the route of drug administration and dosing regimen employed affect the antiinflammatory potency and/or efficacy of compounds on colitis induced by acetic acid in the rat." | 1.28 | Antiinflammatory effects of various drugs on acetic acid induced colitis in the rat. ( Bostwick, JS; Decktor, DL; Fitzpatrick, LR; Pendleton, RG; Renzetti, M, 1990) |
| "The efficacy of various drugs used to treat ulcerative colitis, (sulfasalazine, 5-aminosalicylate, hydrocortisone) was investigated in a model of acetic acid-induced colitis in the rat." | 1.28 | Antiinflammatory effects of various drugs on acetic acid induced colitis in the rat. ( Bostwick, JS; Decktor, DL; Fitzpatrick, LR; Pendleton, RG; Renzetti, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.26) | 18.7374 |
| 1990's | 11 (6.92) | 18.2507 |
| 2000's | 23 (14.47) | 29.6817 |
| 2010's | 54 (33.96) | 24.3611 |
| 2020's | 69 (43.40) | 2.80 |
| Authors | Studies |
|---|---|
| El-Sherbiny, M | 1 |
| Eisa, NH | 1 |
| Abo El-Magd, NF | 1 |
| Elsherbiny, NM | 2 |
| Said, E | 2 |
| Khodir, AE | 2 |
| Hafez, HM | 3 |
| Ibrahim, MA | 3 |
| Yehia Abdelzaher, W | 2 |
| Gad, AA | 1 |
| Mohammed Naguib Abdel Hafez, S | 1 |
| Abdel-Gaber, SA | 2 |
| Geng, Y | 1 |
| Yue, Y | 1 |
| Guan, Q | 1 |
| Ren, Y | 1 |
| Guo, L | 1 |
| Fan, Y | 1 |
| Lu, ZM | 1 |
| Shi, JS | 1 |
| Xu, ZH | 1 |
| Antar, SA | 1 |
| Kh ElMahdy, M | 1 |
| Javaid, F | 1 |
| Aslam, N | 1 |
| Arshad, HM | 1 |
| Awan, AM | 1 |
| Majeed, W | 1 |
| Jabeen, Q | 1 |
| Fattahi, N | 1 |
| Abdolahi, A | 1 |
| Vahabzadeh, Z | 1 |
| Nikkhoo, B | 1 |
| Manoochehri, F | 1 |
| Goudarzzadeh, S | 1 |
| Hassanzadeh, K | 1 |
| Izadpanah, E | 1 |
| Moloudi, MR | 1 |
| Abdel-Wahab, BA | 1 |
| Alkahtani, SA | 1 |
| Alqahtani, AA | 1 |
| Hassanein, EHM | 1 |
| Abdelmonaem, AA | 1 |
| Abdel Hafez, SMN | 1 |
| Zaghloul, MS | 1 |
| Elshal, M | 1 |
| Abdelmageed, ME | 2 |
| El-Desoky Mohamady, RE | 1 |
| Elwia, SK | 1 |
| Abo El Wafa, SM | 1 |
| Mohamed, MA | 1 |
| Makled, MN | 2 |
| Serrya, MS | 2 |
| El-Sheakh, AR | 2 |
| Ahmed, O | 1 |
| Farid, A | 2 |
| Elamir, A | 1 |
| Bastaki, SMA | 2 |
| Amir, N | 2 |
| Adeghate, E | 2 |
| Ojha, S | 1 |
| Salama, RM | 1 |
| Darwish, SF | 1 |
| El Shaffei, I | 1 |
| Elmongy, NF | 1 |
| Fahmy, NM | 1 |
| Afifi, MS | 1 |
| Abdel-Latif, GA | 1 |
| Zhou, BC | 1 |
| Tian, YG | 1 |
| Sun, YN | 1 |
| Liu, YL | 1 |
| Zhao, D | 1 |
| El-Tanbouly, GS | 1 |
| Abdelrahman, RS | 1 |
| Bagalagel, A | 1 |
| Diri, R | 1 |
| Noor, A | 1 |
| Almasri, D | 1 |
| Bakhsh, HT | 1 |
| Kutbi, HI | 1 |
| Al-Gayyar, MMH | 1 |
| Dibekoğlu, C | 1 |
| Erbaş, O | 2 |
| Sheibani, M | 1 |
| Shojaii, A | 1 |
| Noori, M | 1 |
| Motevalian, M | 1 |
| Nasr, M | 1 |
| Cavalu, S | 1 |
| Saber, S | 2 |
| Youssef, ME | 1 |
| Abdelhamid, AM | 1 |
| Elagamy, HI | 1 |
| Kamal, I | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Loop Ileostomy Closure as a 23-hour Stay Procedure, a Multi-center Randomized Controlled Trial[NCT03941522] | 168 participants (Anticipated) | Interventional | 2019-06-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for acetic acid and Colitis Gravis
| Article | Year |
|---|---|
Effect of mesenchymal stem cells derived exosomes and green tea polyphenols on acetic acid induced ulcerative colitis in adult male albino rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Exosomes; Male; Mesenchymal Stem Cells; Polyphenols; Rats | 2022 |
3 trials available for acetic acid and Colitis Gravis
| Article | Year |
|---|---|
Are probiotics effective in the treatment of fungal colonization of the gastrointestinal tract? Experimental and clinical studies.
Topics: Acetic Acid; Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antif | 2006 |
Short-chain fatty acid topical treatment in distal ulcerative colitis.
Topics: Acetates; Acetic Acid; Adult; Butyrates; Butyric Acid; Colitis, Ulcerative; Double-Blind Method; Ene | 1995 |
Treatment of refractory distal ulcerative colitis with short chain fatty acid enemas.
Topics: Acetates; Acetic Acid; Adult; Butyrates; Butyric Acid; Case-Control Studies; Colitis, Ulcerative; En | 1996 |
155 other studies available for acetic acid and Colitis Gravis
| Article | Year |
|---|---|
Anti-inflammatory/anti-apoptotic impact of betulin attenuates experimentally induced ulcerative colitis: An insight into TLR4/NF-kB/caspase signalling modulation.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Apoptosis; Caspase 3; Caspase 8; Colitis, Ulcerative | 2021 |
Protective effect of mirtazapine against acetic acid-induced ulcerative colitis in rats: Role of NLRP3 inflammasome pathway.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Disease Models, Animal; Humans; Inflammasomes; Int | 2021 |
Cereal Vinegar Sediment Alleviates Spontaneous Ulcerative Colitis in Il-10 Deficient Mice.
Topics: Acetic Acid; Animals; Colitis; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Edible Grain; | 2021 |
A novel role of pirfenidone in attenuation acetic acid induced ulcerative colitis by modulation of TGF-β1 / JNK1 pathway.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Caspase 3; Colitis, Ulcerative; Colon; | 2021 |
Gisekia pharnaceoides Restores Colonic Mucosal Homeostasis by Regulating Antioxidant Enzyme System and Cytokines Signaling in Ulcerative Colitis Mice Model.
Topics: Acetic Acid; Aizoaceae; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Colon; | 2022 |
Topical phenytoin administration accelerates the healing of acetic acid-induced colitis in rats: evaluation of transforming growth factor-beta, platelet-derived growth factor, and vascular endothelial growth factor.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Male; Phenytoin; Platelet-Derived Growth Factor; Rats; Ra | 2022 |
Umbelliferone ameliorates ulcerative colitis induced by acetic acid via modulation of TLR4/NF-κB-p65/iNOS and SIRT1/PPARγ signaling pathways in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; NF-kappa B; Nitric Oxide Syntha | 2022 |
Rupatadine ameliorated ulcerative colitis in rats via modulation of platelet-activatiweng factor/interleukin-6/vascular endothelial growth factor signalling pathway.
Topics: Acetic Acid; Animals; Antioxidants; Colitis, Ulcerative; Colon; Cyproheptadine; Histamine; Interleuk | 2022 |
Preventive empagliflozin activity on acute acetic acid-induced ulcerative colitis in rats via modulation of SIRT-1/PI3K/AKT pathway and improving colon barrier.
Topics: Acetic Acid; Animals; Benzhydryl Compounds; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Mod | 2022 |
Fingolimod ameliorates acetic acid-induced ulcerative colitis: An insight into its modulatory impact on pro/anti-inflammatory cytokines and AKT/mTOR signalling.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Cytokines; Fingolimod Hy | 2022 |
Dual role of melatonin as an anti-colitis and anti-extra intestinal alterations against acetic acid-induced colitis model in rats.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Glutathione; Melatonin; Rat | 2022 |
Lycopodium Mitigates Oxidative Stress and Inflammation in the Colonic Mucosa of Acetic Acid-Induced Colitis in Rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Colitis; Colitis, Ulcerat | 2022 |
Morus macroura Miq. Fruit extract protects against acetic acid-induced ulcerative colitis in rats: Novel mechanistic insights on its impact on miRNA-223 and on the TNFα/NFκB/NLRP3 inflammatory axis.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Fruit; Humans; Inflammasomes; MicroRNAs; Morus; NF-kappa | 2022 |
A validated LC-MS/MS method for the determination of hederasaponin C: Application to pharmacokinetics-pharmacodynamics studies in the therapeutic area of acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Interleukin-6; Rats | 2022 |
The emerging coloprotective effect of sildenafil against ulcerative colitis in rats via exerting counterbalance between NF-κB signaling and Nrf-2/HO-1 pathway.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Dexamethasone; NF-kappa B; Rats; Sildenafil Citrat | 2022 |
Curative effects of fucoidan on acetic acid induced ulcerative colitis in rats via modulating aryl hydrocarbon receptor and phosphodiesterase-4.
Topics: Acetic Acid; Alcian Blue; Animals; Antioxidants; Colitis, Ulcerative; Cyclic Nucleotide Phosphodiest | 2022 |
Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model.
Topics: Acetic Acid; Animals; Carbamates; Colitis; Colitis, Ulcerative; Colon; Histone Deacetylase Inhibitor | 2022 |
Evaluation of anti-inflammatory effects of leaf and seed extracts of Plantago major on acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Iran; Plant Extracts; Pl | 2022 |
Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis.
Topics: Acetic Acid; AMP-Activated Protein Kinases; Animals; Canagliflozin; Chitosan; Colitis; Colitis, Ulce | 2022 |
Curcumin-Loaded Microspheres Are Effective in Preventing Oxidative Stress and Intestinal Inflammatory Abnormalities in Experimental Ulcerative Colitis in Rats.
Topics: Acetic Acid; Animals; Antioxidants; Colitis, Ulcerative; Colon; Curcumin; Male; Microspheres; Oxidat | 2022 |
Protective effects of Rubus tereticaulis leaves ethanol extract on rats with ulcerative colitis and bio-guided isolation of its active compounds: A combined in silico, in vitro and in vivo study.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Chromatography, Liquid; Colitis; Colit | 2023 |
Dark-purple rice extract modulates gut microbiota composition in acetic acid- and indomethacin-induced inflammatory bowel disease in rats.
Topics: Acetic Acid; Animals; Anthocyanins; Bacteria; Colitis, Ulcerative; Crohn Disease; Gastrointestinal M | 2023 |
Dark-purple rice extract modulates gut microbiota composition in acetic acid- and indomethacin-induced inflammatory bowel disease in rats.
Topics: Acetic Acid; Animals; Anthocyanins; Bacteria; Colitis, Ulcerative; Crohn Disease; Gastrointestinal M | 2023 |
Dark-purple rice extract modulates gut microbiota composition in acetic acid- and indomethacin-induced inflammatory bowel disease in rats.
Topics: Acetic Acid; Animals; Anthocyanins; Bacteria; Colitis, Ulcerative; Crohn Disease; Gastrointestinal M | 2023 |
Dark-purple rice extract modulates gut microbiota composition in acetic acid- and indomethacin-induced inflammatory bowel disease in rats.
Topics: Acetic Acid; Animals; Anthocyanins; Bacteria; Colitis, Ulcerative; Crohn Disease; Gastrointestinal M | 2023 |
Icosapent ethyl alleviates acetic acid-induced ulcerative colitis via modulation of SIRT1 signaling pathway in rats.
Topics: Acetic Acid; Animals; Caspase 3; Colitis; Colitis, Ulcerative; Collagen; Colon; Eicosapentaenoic Aci | 2023 |
Neuroprotective effects of methyl jasmonate in male Wistar rats exposed to delayed acetic acid-induced ulcerative colitis: involvement of antioxidant status, GFAP, and IBA-1 immunoreactivities.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Male; Neuroprotective Agent | 2023 |
Preventive effect of tilapia skin collagen hydrolysates on ulcerative colitis mice based on metabonomic and 16 S rRNA gene sequencing.
Topics: Acetic Acid; Actinobacteria; Animals; Bacteroidetes; Butyric Acid; Colitis; Colitis, Ulcerative; Col | 2023 |
Sophorolipids produced by Yarrowia lipolytica grown on Moringa oleifera oil cake protect against acetic acid-induced colitis in rats: impact on TLR-4/p-JNK/NFκB-p65 pathway.
Topics: Acetic Acid; Animals; Chromatography, Liquid; Colitis; Colitis, Ulcerative; Colon; Moringa oleifera; | 2023 |
Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia activity.
Topics: Acetic Acid; Acetylcholinesterase; Animals; Antioxidants; Cognitive Dysfunction; Colitis; Colitis, U | 2023 |
Comparative study between histochemical mucus volume, histopathological findings, and endocytoscopic scores in patients with ulcerative colitis.
Topics: Acetic Acid; Chloroform; Colitis, Ulcerative; Female; Humans; Male; Middle Aged; Mucus | 2023 |
The possible effect of lycopene in ameliorating experimentally induced ulcerative colitis in adult male albino rats (A histological, immunohistochemical, and ultrastructural study).
Topics: Acetic Acid; Adult; Antioxidants; Colitis, Ulcerative; Humans; Lycopene; Male; Rats | 2023 |
Therapeutic and prophylactic role of vitamin D and curcumin in acetic acid-induced acute ulcerative colitis model.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Colitis, Ulcerative; Colon; C | 2023 |
Ezetimibe alleviates acetic acid-induced ulcerative colitis in rats: targeting the Akt/NF-κB/STAT3/CXCL10 signaling axis.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Colorectal Neoplasms; Ezetimibe; NF-kappa B; Proto | 2023 |
Imatinib mitigates experimentally-induced ulcerative colitis: Possible contribution of NF-kB/JAK2/STAT3/COX2 signaling pathway.
Topics: Acetic Acid; Animals; Colitis; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Glutathione; Imatinib M | 2023 |
Design and characterization of dexamethasone loaded microsponges for the management of ulcerative colitis.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Dexamethasone; Drug Delivery Systems; Rats | 2023 |
Reduce the Changes in Histological Features of Colon Resulting from Induced Ulcerative Colitis in Mice by Worm Antigens.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Inflammation; Male; Mice | 2022 |
The coumaric acid and syringic acid ameliorate acetic acid-induced ulcerative colitis in rats via modulator of Nrf2/HO-1 and pro-inflammatory cytokines.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Colon; Coumaric A | 2023 |
Licofelone Attenuates Acetic Acid-Induced Colitis in Rats Through Suppression of the Inflammatory Mediators.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis; Colitis, Ulcerative; Inflammation Mediators | 2023 |
Acetic acid-induced colitis modulating potential of total crude alkaloidal extract of Picralima nitida seeds in rats.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Rats; Rats, Sprague-Dawley | 2023 |
Eicosapentaenoic acid mitigates ulcerative colitis-induced by acetic acid through modulation of NF-κB and TGF-β/ EGFR signaling pathways.
Topics: Acetic Acid; Animals; Antioxidants; Colitis, Ulcerative; Colon; Eicosapentaenoic Acid; ErbB Receptor | 2023 |
The lncRNAs UCA1 and CRNDE target miR-145/TLR4/NF-қB/TNF-α axis in acetic acid-induced ulcerative colitis model: The beneficial role of 3,3-Diindolylmethane.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; MicroRNAs; NF-kappa B; Rats; RNA, Long Noncoding; Toll-Li | 2023 |
Genistein and/or sulfasalazine ameliorate acetic acid-induced ulcerative colitis in rats via modulating INF-γ/JAK1/STAT1/IRF-1, TLR-4/NF-κB/IL-6, and JAK2/STAT3/COX-2 crosstalk.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Genistein; Interleukin-6; NF-kap | 2023 |
Topotecan alleviates acetic acid-induced ulcerative colitis in rats via attenuation of the RORγT transcription factor.
Topics: Acetic Acid; Animals; Colitis; Colitis, Ulcerative; Colon; Interleukin-17; Nuclear Receptor Subfamil | 2023 |
Mirabegron alleviates acetic acid-induced colitis in rats: Role of adiponectin and GSTM1/GSH detoxification pathway.
Topics: Acetic Acid; Adiponectin; Animals; Colitis; Colitis, Ulcerative; Colon; Glutathione; Male; NF-kappa | 2023 |
Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the inflammatory, oxidative and apoptotic conditions in the colon tissue.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Inflammation; Lipopolysacch | 2023 |
Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4-NF-κB and NF-κB-INOS-NO signaling pathways.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Inflammation; Male; NF-kappa B; Ni | 2023 |
Co-administration of Thymoquinone and Propolis in Liposomal Formulations as a Potential Approach for Treatment of Acetic Acid-Induced Ulcerative Colitis: Physiological and Histopathological Analysis.
Topics: Acetic Acid; Colitis; Colitis, Ulcerative; Humans; Inflammation; Liposomes; Propolis | 2023 |
Effects of photobiomodulation in the experimental acetic acid-induced colitis: comparison between male and female.
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Cytokines; Female; Humans; | 2023 |
Potential effects of xylopic acid on acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antigens, Nuclear; Body Weight; Cell Proliferation; | 2019 |
Exploring the therapeutic potential of sodium benzoate in acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Dose-Response Relationship, Drug; Drug Interaction | 2019 |
Febuxostat attenuates ulcerative colitis by the inhibition of NF-κB, proinflammatory cytokines, and oxidative stress in mice.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Colon; Cytokines; | 2019 |
Effect of Sorbus domestica and its active constituents in an experimental model of colitis rats induced by acetic acid.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Colitis, Ulcerative; Colon; | 2020 |
Protection by pure and genistein fortified extra virgin olive oil, canola oil, and rice bran oil against acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Food, Fortified; Genistein; Male; Olive Oil; Plant Oils; | 2020 |
Effect of Sodium Cromoglycate on Acetic Acid-induced Ulcerative Colitis in Mice.
Topics: Acetic Acid; Animals; Case-Control Studies; Colitis, Ulcerative; Colon; Cromolyn Sodium; Intestinal | 2020 |
Efficacy of resveratrol encapsulated microsponges delivered by pectin based matrix tablets in rats with acetic acid-induced ulcerative colitis.
Topics: Acetic Acid; Animals; Antioxidants; Chemistry, Pharmaceutical; Chitosan; Colitis, Ulcerative; Colon; | 2020 |
Gliclazide attenuates acetic acid-induced colitis via the modulation of PPARγ, NF-κB and MAPK signaling pathways.
Topics: Acetic Acid; Animals; Apoptosis; Body Weight; Caspase 3; Caspase Inhibitors; Colitis, Ulcerative; Co | 2020 |
Therapeutic effect of adenosine on experimentally induced acute ulcerative colitis model in rats.
Topics: Acetic Acid; Acute Disease; Adenosine; Animals; Anti-Inflammatory Agents; C-Reactive Protein; Coliti | 2020 |
Anti-Ulcerative Effect of Curcumin-Galactomannoside Complex on Acetic Acid-Induced Experimental Model by Inhibiting Inflammation and Oxidative Stress.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Colitis, Ulcerative; Curcumin; Drug Combinations; Galactose | 2020 |
The interplay of the inhibitory effect of nifuroxazide on NF-κB/STAT3 signaling attenuates acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Antidiarrheals; Colitis, Ulcerative; Colon; Hydroxybenz | 2020 |
Antiulcerogenic effect of melittin via mitigating TLR4/TRAF6 mediated NF-κB and p38MAPK pathways in acetic acid-induced ulcerative colitis in mice.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Colitis, Ulcerative; Colon; Cyclooxyg | 2020 |
Prophylactic effect of aquatic extract of stevia on acetic acid induced-ulcerative colitis in male rats: a possible role of Nrf2 and PPARγ.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Male; NF-E2-Related Factor 2; NF-kappa B; Plant Ex | 2020 |
Aqueous Leaf Extract of
Topics: Acetic Acid; Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Inflammation; Oxidative Str | 2021 |
Jiaolong capsule protects SD rats against 2,4,6-trinitrobenzene sulfonic acid induced colitis.
Topics: Acetic Acid; Animals; Behavior, Animal; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Dinoprostone; | 2021 |
Pharmacologycal activity of peperina (Minthostachys verticillata) on gastrointestinal tract.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Behavior, Animal; Capsaicin; Castor Oil; Colitis, Ul | 2021 |
Protective effect of 6-paradol in acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Colon; Glutathion | 2021 |
Evaluation of the therapeutic effects of mycophenolate mofetil targeting Nrf-2 and NLRP3 inflammasome in acetic acid induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Drug Delivery Systems; Enzyme Inhibitors; Inflammasomes; | 2021 |
Graviola mitigates acetic acid-induced ulcerative colitis in rats: insight on apoptosis and Wnt/Hh signaling crosstalk.
Topics: Acetic Acid; Animals; Annona; Apoptosis; Colitis, Ulcerative; Hedgehog Proteins; Male; Peroxidase; R | 2021 |
Effect of escitalopram on an acetic acid-induced ulcerative colitis model.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Escitalopram; Rats | 2021 |
Study on the effect of the treatment of Periplaneta americana L. extract Ento-B by Dinitrochlorobenzene combined with acetic acid induced UC in rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Dinitrochlorobenzene; Periplaneta; Plant Extracts; | 2021 |
Regulation of IL-6/STAT-3/Wnt axis by nifuroxazide dampens colon ulcer in acetic acid-induced ulcerative colitis model: Novel mechanistic insight.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Colitis, Ulcerative; Disease Mod | 2021 |
Effects of hydro-ethanolic extract of leaves of Maesa lanceolata (Mursinaceae) on acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Ethanol; Maesa; Male; Plant Extracts; Plant Leaves; Rats; | 2021 |
Molsidomine alleviates acetic acid-induced colitis in rats by reducing oxidative stress, inflammation and apoptosis.
Topics: Acetic Acid; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulator | 2021 |
Flavocoxid halts both intestinal and extraintestinal alterations in acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Catechin; Colitis, Ulcerative; Drug Combinations; Peroxidase; Rats | 2022 |
The effect of theophylline on acetic acid induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Disease Models, Animal; | 2017 |
Protective effect of Averrhoa bilimbi L. fruit extract on ulcerative colitis in wistar rats via regulation of inflammatory mediators and cytokines.
Topics: Acetic Acid; Animals; Antioxidants; Averrhoa; Colitis, Ulcerative; Colon; Cytokines; Fruit; Inflamma | 2017 |
Pentane and other volatile organic compounds, including carboxylic acids, in the exhaled breath of patients with Crohn's disease and ulcerative colitis.
Topics: Acetic Acid; Adolescent; Adult; Aged; Biomarkers; Breath Tests; Butadienes; Carboxylic Acids; Coliti | 2017 |
Effect of bevacizumab on acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Bevacizumab; Biomarkers; Colitis, Ulcerative; Dose-R | 2017 |
Development and in vivo evaluation of chitosan beads for the colonic delivery of azathioprine for treatment of inflammatory bowel disease.
Topics: Acetic Acid; Animals; Azathioprine; Catalase; Chitosan; Colitis, Ulcerative; Colon; Drug Carriers; D | 2017 |
Anti-inflammatory, antioxidant and anti-apoptotic activity of diosmin in acetic acid-induced ulcerative colitis.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Colitis, Ulcerative; Colon; | 2018 |
Protective effect of Sesbania grandiflora on acetic acid induced ulcerative colitis in mice by inhibition of TNF-α and IL-6.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Interleukin-6; Male; Mice; Plant Extracts; Sesbania; Tumo | 2018 |
Involvement of central opioid receptors in protective effects of methadone on experimental colitis in rats.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerati | 2018 |
The possible ameliorative effect of simvastatin versus sulfasalazine on acetic acid induced ulcerative colitis in adult rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Biom | 2019 |
Olmesartan ameliorates chemically-induced ulcerative colitis in rats via modulating NFκB and Nrf-2/HO-1 signaling crosstalk.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Colitis, U | 2019 |
Protective effect of Bauhinia tomentosa on acetic acid induced ulcerative colitis by regulating antioxidant and inflammatory mediators.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Bauhinia; Colitis, Ulcerative; Glutathione; Glutathi | 2013 |
Effects of curcumin on apoptosis and oxidoinflammatory regulation in a rat model of acetic acid-induced colitis: the roles of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Colitis, Ulcerative; Colon; | 2013 |
Protective effects of hydrogen-rich saline on ulcerative colitis rat model.
Topics: Acetic Acid; Animals; Antioxidants; Colitis, Ulcerative; Disease Models, Animal; Hydrogen; Injection | 2013 |
Protective effects of N-acetylcysteine on acetic acid-induced colitis in a porcine model.
Topics: Acetic Acid; Acetylcysteine; Amphiregulin; Animals; Apoptosis; Caspase 3; Claudin-1; Colitis; Coliti | 2013 |
Protective effect of naringenin on acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Colitis, Ulcerative; Drug Evaluation, Preclinical; Flavanon | 2013 |
Amentoflavone inhibits iNOS, COX-2 expression and modulates cytokine profile, NF-κB signal transduction pathways in rats with ulcerative colitis.
Topics: Acetic Acid; Animals; Biflavonoids; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Cyclooxygenase 2 I | 2013 |
Mesalazine-probiotics beads for acetic acid experimental colitis: formulation and characterization of a promising new therapeutic strategy for ulcerative colitis.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Colitis, Ulcerative; C | 2015 |
Pretreatment of Gymnema sylvestre revealed the protection against acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Colitis; Colitis, Ulcerative | 2014 |
The in vivo and in vitro study of polysaccharides from a two-herb formula on ulcerative colitis and potential mechanism of action.
Topics: Acetic Acid; Amine Oxidase (Copper-Containing); Animals; Astragalus propinquus; Colitis, Ulcerative; | 2014 |
Modulating effect of Biophytum sensitivum extract on rats with acetic acid-induced ulcerative colitis.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Disease Models, Animal; Dose-Response Relationship, Drug; | 2014 |
The protective effect of Echinacea spp. (Echinacea angustifolia and Echinacea purpurea) in a rat colitis model induced by acetic acid.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Disease Models, Animal; Echinacea; Interleukin-1beta; Mal | 2014 |
Anti-inflammatory and immunomodulatory effects of Spirulina platensis in comparison to Dunaliella salina in acetic acid-induced rat experimental colitis.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Immunologic Factors; Lipid Pero | 2015 |
Effect of piperine on inhibition of FFA induced TLR4 mediated inflammation and amelioration of acetic acid induced ulcerative colitis in mice.
Topics: Acetic Acid; Alkaloids; Animals; Anti-Inflammatory Agents; Benzodioxoles; Colitis, Ulcerative; Colon | 2015 |
Intraperitoneal administration of butyrate prevents the severity of acetic acid colitis in rats.
Topics: Acetic Acid; Administration, Oral; Administration, Rectal; Animals; Butyric Acid; Colitis, Ulcerativ | 2015 |
Embelin lipid nanospheres for enhanced treatment of ulcerative colitis - Preparation, characterization and in vivo evaluation.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Benzoquinones; Chemistry, Pharmaceutical; Coconut Oi | 2015 |
Evaluation of the protective effect of Pterocarpus marsupium on acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Disease Models, A | 2015 |
Protective effect of cavidine on acetic acid-induced murine colitis via regulating antioxidant, cytokine profile and NF-κB signal transduction pathways.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Berberine Alkaloids; Colitis, Ulcerative; Col | 2015 |
Co-administration of α-lipoic acid and cyclosporine aggravates colon ulceration of acetic acid-induced ulcerative colitis via facilitation of NO/COX-2/miR-210 cascade.
Topics: Acetic Acid; Animals; C-Reactive Protein; Catalase; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Cy | 2015 |
Vinegar Treatment Prevents the Development of Murine Experimental Colitis via Inhibition of Inflammation and Apoptosis.
Topics: Acetic Acid; Animals; Apoptosis; Colitis, Ulcerative; Colon; Cytokines; Disease Models, Animal; Huma | 2016 |
Effect of turmeric on colon histology, body weight, ulcer, IL-23, MPO and glutathione in acetic-acid-induced inflammatory bowel disease in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Colitis, Ulcerative; Colo | 2016 |
Medical ozone treatment ameliorates the acute distal colitis in rat.
Topics: Acetic Acid; Acute Disease; Animals; Colitis, Ulcerative; Colon; Disease Models, Animal; Immunohisto | 2016 |
Protective effect of Periplaneta americana extract in ulcerative colitis rats induced by dinitrochlorobenzene and acetic acid.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Collagen; Complementary Therapies; Dinitrochlorobenzene; | 2016 |
Development of enteric-coated microspheres of embelin for their beneficial pharmacological potential in ulcerative colitis.
Topics: Acetic Acid; Animals; Benzoquinones; Coated Materials, Biocompatible; Colitis, Ulcerative; Disease M | 2017 |
Exogenous Ghrelin Accelerates the Healing of Acetic Acid-Induced Colitis in Rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; DNA; Ghrelin; Interleukin-1beta; Intestinal Mucosa; Male; | 2016 |
Beneficial effect of Amorphophallus paeoniifolius tuber on experimental ulcerative colitis in rats.
Topics: Acetic Acid; Alkaline Phosphatase; Amorphophallus; Animals; Anti-Inflammatory Agents; Biomarkers; Ca | 2017 |
Hydroalcoholic extract of Brazilian red propolis exerts protective effects on acetic acid-induced ulcerative colitis in a rodent model.
Topics: Acetic Acid; Animals; Chemical Fractionation; Colitis, Ulcerative; Dose-Response Relationship, Drug; | 2017 |
Protective effect of cardamonin against acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Caspase 3; Chalcones; Colitis, Ulcerative; Colon; Cy | 2017 |
Protective effects of lithium on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Antipsychotic Agents; Colitis, Ulcerative; Colon; Lithium Compounds; Male; Mal | 2009 |
Protective effects of selenium and vitamin E combination on experimental colitis in blood plasma and colon of rats.
Topics: Acetic Acid; Animals; Antioxidants; Catalase; Colitis, Ulcerative; Colon; Dipeptidases; Oxidative St | 2010 |
[Synthesis of 2-hydroxyl-5-butyramidobenzoic acid and its effect on acetic acid-induced colitis in rats].
Topics: Acetic Acid; Aminobenzoates; Animals; Colitis, Ulcerative; Male; Protective Agents; Rats; Rats, Spra | 2009 |
L-arginine augments the antioxidant effect of garlic against acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Antioxidants; Arginine; Catalase; Chemistry, Pharmaceutical; Colitis, Ulcerati | 2009 |
Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Colitis, Ulcerative; Co | 2011 |
Evidence for the complementary and synergistic effects of the three-alkaloid combination regimen containing berberine, hypaconitine and skimmianine on the ulcerative colitis rats induced by trinitrobenzene-sulfonic acid.
Topics: Acetic Acid; Aconitine; Alkaloids; Analgesics; Animals; Antidiarrheals; Behavior, Animal; Berberine; | 2011 |
Protective effect of embelin against acetic acid induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Benzoquinones; Colitis, Ulcerative; Di | 2011 |
[Effects of glutamine on the colon of mice subjected to colitis gravis].
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Female; Glutamine; Male; Mice; Random Allocation | 2009 |
Role of nitric oxide-synthase and cyclooxygenase/lipooxygenase systems in development of experimental ulcerative colitis.
Topics: Acetic Acid; Animals; Antioxidants; Arachidonate 5-Lipoxygenase; Arginine; Benzoquinones; Celecoxib; | 2011 |
Keratinocyte growth factor gene therapy ameliorates ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Female; Fibroblast Growth Factor 7; Genetic Therap | 2011 |
Vitamin E has a dual effect of anti-inflammatory and antioxidant activities in acetic acid-induced ulcerative colitis in rats.
Topics: Acetic Acid; Animals; Antioxidants; Colitis, Ulcerative; Colon; Disease Models, Animal; Female; Inte | 2011 |
Inhibition of acute experimental colitis by a crude extract and diets containing seeds of Garcinia kola (heckel).
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Di | 2010 |
Anti-inflammatory effect of 3,4-oxo-isopropylidene-shikimic acid on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Male; Malondialde | 2012 |
Potential of Moringa oleifera root and Citrus sinensis fruit rind extracts in the treatment of ulcerative colitis in mice.
Topics: Acetic Acid; Animals; Citrus sinensis; Colitis, Ulcerative; Disease Models, Animal; Dose-Response Re | 2012 |
Curative effect of Terminalia chebula extract on acetic acid-induced experimental colitis: role of antioxidants, free radicals and acute inflammatory marker.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Biomarkers; Colitis, Ulcerative; Disease Mode | 2013 |
N-acetylcysteine expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic acid-induced colitis in rats.
Topics: Acetic Acid; Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; C | 2013 |
Effect of marine mangrove Avicennia marina (Forssk.) Vierh against acetic acid-induced ulcerative colitis in experimental mice.
Topics: Acetic Acid; Animals; Avicennia; Colitis, Ulcerative; Colon; Disease Models, Animal; Glutathione; Gl | 2012 |
Protective effect of sanguinarine against acetic acid-induced ulcerative colitis in mice.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzophenanthridines; Colitis, Ulcera | 2013 |
Effects of trimetazidine on acetic acid-induced colitis in female Swiss rats.
Topics: Acetic Acid; Administration, Rectal; Animals; Colitis, Ulcerative; Disease Models, Animal; Female; G | 2003 |
Colonic ulceration and increase of neutrophil elastase activity in the acetic acid-induced colitis model in Syrian hamsters.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Cricetinae; Disease Models, Animal; Histological T | 2004 |
Effect of hyperbaric oxygen on experimental acute distal colitis.
Topics: Acetic Acid; Animals; Antioxidants; Colitis, Ulcerative; Hyperbaric Oxygenation; Male; Rats; Rats, S | 2004 |
Morphology of colorectal lymphoid aggregates in cancer, diverticular and inflammatory bowel diseases.
Topics: Acetic Acid; Adult; Aged; Aged, 80 and over; Antigens, CD20; CD3 Complex; Colitis, Ulcerative; Color | 2005 |
Proglumide attenuates experimental colitis in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cholecystokinin; Colitis, Ulcerative; Disease Models, Anima | 2005 |
Azithromycin and erythromycin ameliorate the extent of colonic damage induced by acetic acid in rats.
Topics: Acetic Acid; Animals; Azithromycin; Colitis, Ulcerative; Colon; Disease Models, Animal; Dose-Respons | 2005 |
Ginkgo biloba attenuates mucosal damage in a rat model of ulcerative colitis.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Disease Models, Animal; Ginkgo biloba; Glutathione; Inter | 2006 |
[Intestinal mucosa protection of muscovite n ulcerative colitis in rats].
Topics: Acetic Acid; Aluminum Silicates; Animals; Colitis, Ulcerative; Colon; Intestinal Mucosa; Male; Mater | 2005 |
Hyperbaric oxygen enhances the efficiency of 5-aminosalicylic acid in acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Combined Modality Therapy; Disease Models, Animal; Female | 2006 |
Effects of L-carnitine on oxidant/antioxidant status in acetic acid-induced colitis.
Topics: Acetic Acid; Animals; Carnitine; Colitis, Ulcerative; Disease Models, Animal; Inflammation Mediators | 2006 |
Chronic colitis promotes tumor development.
Topics: 1,2-Dimethylhydrazine; Acetic Acid; Animals; Carcinogens; Cell Growth Processes; Cocarcinogenesis; C | 2006 |
[Therapeutic effects of pravastatin on colitis induced by acetic acid and relevant mechanism: experiment with rats].
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Disease Models, Animal; Male; Malondialdehyde; Nit | 2006 |
Anti-inflammatory effect of Diammonium Glycyrrhizinate in a rat model of ulcerative colitis.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Disease Models, Animal; Female; | 2006 |
Ameliorative effect of pyrrolidinedithiocarbamate on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Glutathione; L-Lactate Dehydrogenase; Lipid Peroxi | 2007 |
Endorectal ileal pullthrough procedure after chemical debridement of the rectal mucosa.
Topics: Acetates; Acetic Acid; Anal Canal; Animals; Colectomy; Colitis, Ulcerative; Debridement; Dogs; Femal | 1984 |
Colonic fermentation: metabolic and clinical implications.
Topics: Acetates; Acetic Acid; Anaerobiosis; Animals; Butyrates; Butyric Acid; Cell Division; Colitis, Ulcer | 1994 |
Impairment of bacterial flora in human ulcerative colitis and experimental colitis in the rat.
Topics: Acetates; Acetic Acid; Animals; Bacteria, Anaerobic; Colitis; Colitis, Ulcerative; Colon; Enterobact | 1993 |
Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis.
Topics: Acetic Acid; Aminosalicylic Acids; Animals; Antioxidants; Butylated Hydroxytoluene; Colitis; Colitis | 1996 |
Role of copper zinc superoxide dismutase in the short-term treatment of acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Intestinal Mucosa; Lipid Peroxi | 1996 |
Enhanced mucosal re-epithelialization induced by short chain fatty acids in experimental colitis.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Epithelium; Fatty Acids, Volatile; Glucose Solution, Hype | 1999 |
[The new experimental ulcerative colitis model in rats induced by subserosal injection of acetic acid].
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Disease Models, Animal; Inflamm | 2001 |
Novel antioxidants zolimid and AEOL11201 ameliorate colitis in rats.
Topics: Acetic Acid; Amino Acids; Animals; Antioxidants; Colitis, Ulcerative; Colon; Disease Models, Animal; | 2001 |
Studies on the expression and function of beta-3-adrenoceptors in the colon of rats with acetic acid-induced colitis.
Topics: Acetic Acid; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colitis, Ulcerative; Co | 2002 |
Effects of pleuran (beta-glucan isolated from Pleurotus ostreatus) on experimental colitis in rats.
Topics: Acetic Acid; Adjuvants, Immunologic; Administration, Oral; Animals; beta-Glucans; Colitis, Ulcerativ | 2001 |
Acetic acid-induced colitis in the rat: a reproducible experimental model for acute ulcerative colitis.
Topics: Acetates; Acetic Acid; Animals; Castor Oil; Colitis, Ulcerative; Disease Models, Animal; Dose-Respon | 1992 |
Role of neutrophils in acetic acid-induced colitis in rats.
Topics: Acetates; Acetic Acid; Animals; Colitis, Ulcerative; Colon; Intestinal Mucosa; Male; Neutrophils; Or | 1991 |
Antiinflammatory effects of various drugs on acetic acid induced colitis in the rat.
Topics: Acetates; Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; | 1990 |
Misoprostol provides a colonic mucosal protective effect during acetic acid-induced colitis in rats.
Topics: Acetates; Acetic Acid; Alprostadil; Aminosalicylic Acids; Animals; Anti-Ulcer Agents; Betamethasone; | 1990 |
Inflammation-induced intestinal hyperemia in the rat: role of neutrophils.
Topics: Acetates; Acetic Acid; Animals; Colitis, Ulcerative; Colon; Hyperemia; Male; Neutrophils; Peroxidase | 1988 |