Page last updated: 2024-10-16

acetic acid and Alloxan Diabetes

acetic acid has been researched along with Alloxan Diabetes in 23 studies

Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.

Research Excerpts

ExcerptRelevanceReference
"When acetic acid was taken daily by obesity-linked type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats under the fed condition, it protected OLETF rats against obesity."6.53Biological Function of Acetic Acid-Improvement in Obesity and Glucose Tolerance by Acetic Acid in Type 2 Diabetic Rats. ( Yamashita, H, 2016)
" Six weeks following streptozotocin or saline injection, gastric ulcers were induced by serosal application of acetic acid."3.77Role of activation of 5'-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats. ( Baraka, AM; Deif, MM, 2011)
"The potential utility of 5'-adenosine monophosphate-activated protein kinase (AMPK)-activating agents, such as metformin, in inducing angiogenesis, could be a promising approach to promote healing of gastric ulcers complicated by diabetes mellitus."3.77Role of activation of 5'-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats. ( Baraka, AM; Deif, MM, 2011)
"Administration of metformin, but not pioglitazone, resulted in a significant decrease in the gastric ulcer area, a significant increase in epithelial regeneration assessed histologically, a significant increase in the number of microvessels in the ulcer margin, a significant increase in gastric vascular endothelial growth factor concentration and gastric von Willebrand factor as well as a significant increase in gastric phospho-AMPK."3.77Role of activation of 5'-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats. ( Baraka, AM; Deif, MM, 2011)
" The antinociceptive effect of the plant's extract was evaluated by the "hot-plate" and "acetic acid" test models of pain in mice, while the antiinflammatory and antidiabetic effects of the leaf extract were investigated in rats, using fresh egg albumin-induced paw edema, and streptozotocin (STZ)-induced diabetes mellitus, respectively."3.73Antinociceptive, antiinflammatory and antidiabetic effects of Leonotis leonurus (L.) R. BR. [Lamiaceae] leaf aqueous extract in mice and rats. ( Ojewole, JA, 2005)
"Gastric ulcers were induced in normal/NIDDM rats by various physical (2 hr cold restraint stress and 4 hr pylorus ligation) and chemical agents (ethanol, 1 ml/200 g, oral, 1 hr before; aspirin, 200 mg/kg, oral, 4 hr) and duodenal ulcers were induced by cysteamine (40 mg/200 g)."3.72Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats. ( Agrawal, VK; Aryya, NC; Dorababu, M; Goel, RK; Prabha, T; Priyambada, S, 2004)
"When acetic acid was taken daily by obesity-linked type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats under the fed condition, it protected OLETF rats against obesity."2.53Biological Function of Acetic Acid-Improvement in Obesity and Glucose Tolerance by Acetic Acid in Type 2 Diabetic Rats. ( Yamashita, H, 2016)
"Rotarod and catalepsy tests were used to identify potential side effects, while the functional effect of TRR469 was studied using [(3)H]-d-aspartate release from synaptosomes."1.40TRR469, a potent A(1) adenosine receptor allosteric modulator, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice. ( Baraldi, PG; Borea, PA; Gessi, S; Merighi, S; Romagnoli, R; Targa, M; Varani, K; Vincenzi, F, 2014)
"TRR469 was anti-allodynic in the neuropathic pain model and did not display locomotor or cataleptic side effects."1.40TRR469, a potent A(1) adenosine receptor allosteric modulator, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice. ( Baraldi, PG; Borea, PA; Gessi, S; Merighi, S; Romagnoli, R; Targa, M; Varani, K; Vincenzi, F, 2014)
"Gastric ulcers were induced in normal/NIDDM rats by various physical (2 hr cold restraint stress and 4 hr pylorus ligation) and chemical agents (ethanol, 1 ml/200 g, oral, 1 hr before; aspirin, 200 mg/kg, oral, 4 hr) and duodenal ulcers were induced by cysteamine (40 mg/200 g)."1.32Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats. ( Agrawal, VK; Aryya, NC; Dorababu, M; Goel, RK; Prabha, T; Priyambada, S, 2004)
"01) even at a dosage of 0."1.31Studies on non-thiazolidinedione antidiabetic agents. 1. Discovery of novel oxyiminoacetic acid derivatives. ( Imamiya, E; Imoto, H; Kimura, H; Momose, Y; Sohda, T; Sugiyama, Y, 2002)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's1 (4.35)18.2507
2000's8 (34.78)29.6817
2010's12 (52.17)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Xia, T1
Zhang, Z1
Zhao, Y1
Kang, C1
Zhang, X1
Tian, Y1
Yu, J1
Cao, H1
Wang, M1
Muangchan, N1
Kooptiwut, S1
Tapechum, S1
Akarasereenont, P1
Vongsopanagul, N1
Pongwattanapakin, K1
Chaikomin, R1
Karim, N1
Rahman, A1
Chanudom, L1
Thongsom, M1
Tangpong, J1
Sobeh, M1
El-Raey, M1
Rezq, S1
Abdelfattah, MAO1
Petruk, G1
Osman, S1
El-Shazly, AM1
El-Beshbishy, HA1
Mahmoud, MF1
Wink, M1
Szlachcic, A1
Majka, J1
Strzalka, M1
Szmyd, J1
Pajdo, R1
Ptak-Belowska, A1
Kwiecien, S1
Brzozowski, T1
Vincenzi, F1
Targa, M1
Romagnoli, R1
Merighi, S1
Gessi, S1
Baraldi, PG1
Borea, PA1
Varani, K1
Yamashita, H1
Kim, HJ1
Park, SY1
Kim, DG1
Park, SH1
Lee, H1
Hwang, DY1
Jung, MH1
Ha, KT1
Kim, BJ1
Shishehbor, F1
Mansoori, A1
Sarkaki, AR1
Jalali, MT1
Latifi, SM1
Yang, Z1
Dolber, PC1
Fraser, MO1
Baraka, AM2
Guemei, A1
Gawad, HA1
Gu, X1
Zhao, HL1
Sui, Y1
Guan, J1
Chan, JC1
Tong, PC1
Chen, X1
Zhu, C1
Guo, F1
Qiu, X1
Yang, Y1
Zhang, S1
He, M1
Parveen, S1
Jing, C1
Li, Y1
Ma, B1
Deif, MM1
Imoto, H1
Imamiya, E1
Momose, Y1
Sugiyama, Y1
Kimura, H1
Sohda, T1
Sinner, D1
Caviglia, JM1
Jawerbaum, A1
Igal, RA1
Gonzalez, E1
Dorababu, M1
Prabha, T1
Priyambada, S1
Agrawal, VK1
Aryya, NC1
Goel, RK1
Van Zandt, MC1
Sibley, EO1
McCann, EE1
Combs, KJ1
Flam, B1
Sawicki, DR1
Sabetta, A1
Carrington, A1
Sredy, J1
Howard, E1
Mitschler, A1
Podjarny, AD1
Mahomed, IM1
Ojewole, JA3
Reiser, KM1
Crouch, EC1
Chang, K1
Williamson, JR1
Smith, DM1
Fuller, SJ1
Sugden, PH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Apple Cider Vinegar for the Prevention of Urinary Lithiasis (APUL)[NCT04073719]50 participants (Anticipated)Interventional2019-09-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for acetic acid and Alloxan Diabetes

ArticleYear
Biological Function of Acetic Acid-Improvement in Obesity and Glucose Tolerance by Acetic Acid in Type 2 Diabetic Rats.
    Critical reviews in food science and nutrition, 2016, Jul-29, Volume: 56 Suppl 1

    Topics: Acetate-CoA Ligase; Acetic Acid; Adipose Tissue; Animals; Diabetes Mellitus, Experimental; Diabetes

2016

Other Studies

22 other studies available for acetic acid and Alloxan Diabetes

ArticleYear
The anti-diabetic activity of polyphenols-rich vinegar extract in mice via regulating gut microbiota and liver inflammation.
    Food chemistry, 2022, Nov-01, Volume: 393

    Topics: Acetic Acid; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gastrointestinal M

2022
    Biological & pharmaceutical bulletin, 2017, Volume: 40, Issue:9

    Topics: Acetic Acid; Animals; Blood Glucose; Body Weight; Breath Tests; Cell Count; Diabetes Mellitus, Exper

2017
Mangosteen Vinegar Rind from Garcinia mangostana Prevents High-Fat Diet and Streptozotocin-Induced Type II Diabetes Nephropathy and Apoptosis.
    Journal of food science, 2019, Volume: 84, Issue:5

    Topics: Acetic Acid; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High

2019
Chemical profiling of secondary metabolites of Eugenia uniflora and their antioxidant, anti-inflammatory, pain killing and anti-diabetic activities: A comprehensive approach.
    Journal of ethnopharmacology, 2019, Aug-10, Volume: 240

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Antipyretics; Carrageenan;

2019
Experimental healing of preexisting gastric ulcers induced by hormones controlling food intake ghrelin, orexin-A and nesfatin-1 is impaired under diabetic conditions. A key to understanding the diabetic gastropathy?
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2013, Volume: 64, Issue:5

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Calcium-Binding Proteins; Diabetes Mellitus, Experimental;

2013
TRR469, a potent A(1) adenosine receptor allosteric modulator, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice.
    Neuropharmacology, 2014, Volume: 81

    Topics: Acetic Acid; Allosteric Regulation; Analgesics; Animals; Catalepsy; CHO Cells; Cricetinae; Cricetulu

2014
Effects of the roots of Liriope Platyphylla Wang Et tang on gastrointestinal motility function.
    Journal of ethnopharmacology, 2016, May-26, Volume: 184

    Topics: Acetic Acid; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Gastrointestinal Motility; G

2016
Apple cider vinegar attenuates lipid profile in normal and diabetic rats.
    Pakistan journal of biological sciences : PJBS, 2008, Dec-01, Volume: 11, Issue:23

    Topics: Acetic Acid; Animals; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Experimental; Glycated Hemog

2008
Differential vulnerabilities of urethral afferents in diabetes and discovery of a novel urethra-to-urethra reflex.
    American journal of physiology. Renal physiology, 2010, Volume: 298, Issue:1

    Topics: Acetic Acid; Animals; Capsaicin; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Respo

2010
Role of modulation of vascular endothelial growth factor and tumor necrosis factor-alpha in gastric ulcer healing in diabetic rats.
    Biochemical pharmacology, 2010, Jun-01, Volume: 79, Issue:11

    Topics: Acetic Acid; Animals; Anticholesteremic Agents; Diabetes Mellitus, Experimental; Free Radical Scaven

2010
White rice vinegar improves pancreatic beta-cell function and fatty liver in streptozotocin-induced diabetic rats.
    Acta diabetologica, 2012, Volume: 49, Issue:3

    Topics: Acetic Acid; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drinking; Eating;

2012
Acetic acid derivatives of 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide as a novel class of potent aldose reductase inhibitors.
    Journal of medicinal chemistry, 2010, Dec-09, Volume: 53, Issue:23

    Topics: Acetic Acid; Aldehyde Reductase; Animals; Benzothiadiazines; Cyclic S-Oxides; Diabetes Mellitus, Exp

2010
Role of activation of 5'-adenosine monophosphate-activated protein kinase in gastric ulcer healing in diabetic rats.
    Pharmacology, 2011, Volume: 88, Issue:5-6

    Topics: Acetic Acid; Animals; Blood Glucose; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Experi

2011
Studies on non-thiazolidinedione antidiabetic agents. 1. Discovery of novel oxyiminoacetic acid derivatives.
    Chemical & pharmaceutical bulletin, 2002, Volume: 50, Issue:10

    Topics: Acetic Acid; Animals; Diabetes Mellitus, Experimental; Female; Humans; Hypoglycemic Agents; Imino Ac

2002
Lipid metabolism in the embryos of diabetic rats during early organogenesis: modulatory effect of prostaglandin E2.
    Reproduction, fertility, and development, 2003, Volume: 15, Issue:1-2

    Topics: Acetic Acid; Animals; Carbon Radioisotopes; Cholesterol; Cholesterol Esters; Diabetes Mellitus, Expe

2003
Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:4

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Aspirin; Azadirachta; Bacopa; Cold Temperature; Diabetes Me

2004
Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications.
    Bioorganic & medicinal chemistry, 2004, Nov-01, Volume: 12, Issue:21

    Topics: Acetic Acid; Aldehyde Reductase; Animals; Chronic Disease; Diabetes Mellitus, Experimental; Drug Des

2004
Analgesic, antiinflammatory and antidiabetic properties of Harpagophytum procumbens DC (Pedaliaceae) secondary root aqueous extract.
    Phytotherapy research : PTR, 2004, Volume: 18, Issue:12

    Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blo

2004
Antinociceptive, anti-inflammatory and antidiabetic effects of Bryophyllum pinnatum (Crassulaceae) leaf aqueous extract.
    Journal of ethnopharmacology, 2005, May-13, Volume: 99, Issue:1

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Crassulace

2005
Antinociceptive, antiinflammatory and antidiabetic effects of Leonotis leonurus (L.) R. BR. [Lamiaceae] leaf aqueous extract in mice and rats.
    Methods and findings in experimental and clinical pharmacology, 2005, Volume: 27, Issue:4

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Blood G

2005
Lysyl oxidase-mediated crosslinking in granulation tissue collagen in two models of hyperglycemia.
    Biochimica et biophysica acta, 1991, Jul-26, Volume: 1097, Issue:1

    Topics: Acetates; Acetic Acid; Analysis of Variance; Animals; Blood Glucose; Collagen; Diabetes Mellitus, Ex

1991
The effects of lactate, acetate, glucose, insulin, starvation and alloxan-diabetes on protein synthesis in perfused rat hearts.
    The Biochemical journal, 1986, Jun-01, Volume: 236, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Diabetes Mellitus, Experimental; Food; Glucose; Heart; Insulin; Lact

1986