acetic acid has been researched along with Acute Liver Injury, Drug-Induced in 17 studies
Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
acetic acid : A simple monocarboxylic acid containing two carbons.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a fatal occurrence of massive liver necrosis following ingestion of concentrated (90%) acetic acid, the patient showed evidence of hemolysis, disseminated intravascular coagulation, and liver dysfunction at only 45 minutes after exposure." | 7.70 | Massive noninflammatory periportal liver necrosis following concentrated acetic acid ingestion. ( Iwabuchi, K; Kamijo, Y; Ohwada, T; Soma, K, 2000) |
| "Coconut water vinegar has helped to attenuate acetaminophen-induced liver damage by restoring antioxidant activity and suppression of inflammation." | 3.88 | Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice. ( Alitheen, NB; Beh, BK; Ho, WY; Ky, H; Lim, KL; Long, K; Mohamad, NE; Sharifuddin, SA; Yeap, SK, 2018) |
| "5% inhibition on the vascular permeability change induced by intraperitoneal injection of acetic acid, but it could not inhibit croton oil-induced ear edema." | 3.71 | Anti-oxidative, anti-inflammatory and hepato-protective effects of Ligustrum robustum. ( But, PP; Dong, H; Fung, KP; He, ZD; Lau, KM, 2002) |
| "In a fatal occurrence of massive liver necrosis following ingestion of concentrated (90%) acetic acid, the patient showed evidence of hemolysis, disseminated intravascular coagulation, and liver dysfunction at only 45 minutes after exposure." | 3.70 | Massive noninflammatory periportal liver necrosis following concentrated acetic acid ingestion. ( Iwabuchi, K; Kamijo, Y; Ohwada, T; Soma, K, 2000) |
| " Combining the results of biochemical indexes and metabolomics analysis, both raw BR and VPBR showed toxic effect on rats, whereas vinegar processing reduced its toxicity." | 1.72 | [Toxicity comparison of raw and vinegar-processed Bupleuri Radix based on ~1H-NMR metabolomics]. ( Li, ZY; Qin, XM; Sun, HM; Zhang, T, 2022) |
| " Intraperitoneal or po administration of the new chemical entities (NCEs), 3b and 3r, in concentrations equal to a toxic dose of ApAP did not result in the formation of NAPQI." | 1.56 | A novel pipeline of 2-(benzenesulfonamide)-N-(4-hydroxyphenyl) acetamide analgesics that lack hepatotoxicity and retain antipyresis. ( Abet, V; Alvarez-Builla, J; Bazan, HA; Bazan, NG; Bhattacharjee, S; Burgos, C; Edwards, S; Gordon, WC; Heap, J; Jun, B; Ledet, AJ; Pahng, AR; Paul, D; Recio, J, 2020) |
| " On the other hand, acetaminophen challenged mice treated with 14 days of coconut water vinegar were recorded with reduction of serum liver profiles, improved liver histology, restored liver antioxidant, reduction of liver inflammation and decreased level of liver cytochrome P450 2E1 in dosage dependent level." | 1.48 | Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice. ( Alitheen, NB; Beh, BK; Ho, WY; Ky, H; Lim, KL; Long, K; Mohamad, NE; Sharifuddin, SA; Yeap, SK, 2018) |
| " Baking herb with vinegar is believed to attenuate the adverse responses." | 1.46 | Content decline of SERCA inhibitors saikosaponin a and d attenuates cardiotoxicity and hepatotoxicity of vinegar-baked Radix bupleuri. ( Li, S; Peng, S; Qiao, Y; Shen, C; Wang, S; Wu, Q; Yang, W; Yu, Y; Zhang, M; Zhang, Q; Zhang, Y, 2017) |
| " A dosage of 200 mg of elemental zinc per day was required to achieve therapeutic objectives related to copper, which included a doubling of plasma zinc concentration to 200 micrograms/dl and a suppression of oral 64 copper absorption." | 1.28 | Use of zinc acetate to treat copper toxicosis in dogs. ( Brewer, GJ; Dick, RD; Lindgren, J; Mullaney, TP; Pace, C; Padgett, G; Schall, W; Thomas, M; Yuzbasiyan-Gurkan, V, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Sun, HM | 3 |
| Zhang, T | 2 |
| Li, ZY | 3 |
| Qin, XM | 3 |
| Bazan, HA | 1 |
| Bhattacharjee, S | 1 |
| Burgos, C | 1 |
| Recio, J | 1 |
| Abet, V | 1 |
| Pahng, AR | 1 |
| Jun, B | 1 |
| Heap, J | 1 |
| Ledet, AJ | 1 |
| Gordon, WC | 1 |
| Edwards, S | 1 |
| Paul, D | 1 |
| Alvarez-Builla, J | 1 |
| Bazan, NG | 1 |
| Schleiff, MA | 1 |
| Payakachat, S | 1 |
| Schleiff, BM | 1 |
| Swamidass, SJ | 1 |
| Boysen, G | 1 |
| Miller, GP | 1 |
| Wang, S | 1 |
| Zhang, Y | 2 |
| Zhang, Q | 1 |
| Peng, S | 1 |
| Shen, C | 1 |
| Yu, Y | 1 |
| Zhang, M | 1 |
| Yang, W | 1 |
| Wu, Q | 1 |
| Li, S | 1 |
| Qiao, Y | 1 |
| Mohamad, NE | 1 |
| Yeap, SK | 1 |
| Beh, BK | 1 |
| Ky, H | 1 |
| Lim, KL | 1 |
| Ho, WY | 1 |
| Sharifuddin, SA | 1 |
| Long, K | 1 |
| Alitheen, NB | 1 |
| Bao, BH | 1 |
| Yan, XJ | 1 |
| Cao, YD | 1 |
| Yao, WF | 1 |
| Cheng, FF | 1 |
| Chen, PD | 1 |
| Shan, MQ | 1 |
| Zhang, L | 1 |
| Ding, AW | 1 |
| Xing, J | 1 |
| Du, GH | 1 |
| Lau, KM | 1 |
| He, ZD | 1 |
| Dong, H | 1 |
| Fung, KP | 1 |
| But, PP | 1 |
| Seki, T | 1 |
| Morimura, S | 1 |
| Tabata, S | 1 |
| Tang, Y | 1 |
| Shigematsu, T | 1 |
| Kida, K | 1 |
| Potter, JE | 1 |
| Kawamata, M | 1 |
| Fujita, S | 1 |
| Mayumi, T | 1 |
| Sumita, S | 1 |
| Omote, K | 1 |
| Namiki, A | 1 |
| Kamijo, Y | 1 |
| Soma, K | 1 |
| Iwabuchi, K | 1 |
| Ohwada, T | 1 |
| Brewer, GJ | 1 |
| Dick, RD | 1 |
| Schall, W | 1 |
| Yuzbasiyan-Gurkan, V | 1 |
| Mullaney, TP | 1 |
| Pace, C | 1 |
| Lindgren, J | 1 |
| Thomas, M | 1 |
| Padgett, G | 1 |
| Sedov, KR | 1 |
| Petrun'ko, IL | 1 |
| Gol'dberg, OA | 1 |
| Commandeur, JN | 1 |
| Oostendorp, RA | 1 |
| Schoofs, PR | 1 |
| Xu, B | 1 |
| Vermeulen, NP | 1 |
17 other studies available for acetic acid and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
[Toxicity comparison of raw and vinegar-processed Bupleuri Radix based on ~1H-NMR metabolomics].
Topics: Acetic Acid; Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Liver; Male; Me | 2022 |
[Toxicity comparison of raw and vinegar-processed Bupleuri Radix based on ~1H-NMR metabolomics].
Topics: Acetic Acid; Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Liver; Male; Me | 2022 |
[Toxicity comparison of raw and vinegar-processed Bupleuri Radix based on ~1H-NMR metabolomics].
Topics: Acetic Acid; Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Liver; Male; Me | 2022 |
[Toxicity comparison of raw and vinegar-processed Bupleuri Radix based on ~1H-NMR metabolomics].
Topics: Acetic Acid; Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Liver; Male; Me | 2022 |
A novel pipeline of 2-(benzenesulfonamide)-N-(4-hydroxyphenyl) acetamide analgesics that lack hepatotoxicity and retain antipyresis.
Topics: Acetamides; Acetic Acid; Analgesics; Animals; Antipyretics; Chemical and Drug Induced Liver Injury; | 2020 |
Impacts of diphenylamine NSAID halogenation on bioactivation risks.
Topics: Acetic Acid; Activation, Metabolic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Ava | 2021 |
Content decline of SERCA inhibitors saikosaponin a and d attenuates cardiotoxicity and hepatotoxicity of vinegar-baked Radix bupleuri.
Topics: Acetic Acid; Animals; Animals, Newborn; Apoptosis; Bupleurum; Cardiotoxicity; Cell Line; Cells, Cult | 2017 |
Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice.
Topics: Acetaminophen; Acetic Acid; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cocos; In | 2018 |
Radix Kansui Stir-Fried with Vinegar Reduces Radix Kansui-Related Hepatotoxicity in Mice via Mitochondrial Pathway.
Topics: Acetic Acid; Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Euph | 2021 |
Chemical and biological comparison of raw and vinegar-baked Radix Bupleuri.
Topics: Acetic Acid; Animals; Bupleurum; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Inj | 2015 |
Anti-oxidative, anti-inflammatory and hepato-protective effects of Ligustrum robustum.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Capillary Permea | 2002 |
Antioxidant activity of vinegar produced from distilled residues of the Japanese liquor shochu.
Topics: Acetic Acid; Alcoholic Beverages; Animals; Antioxidants; Carbon Tetrachloride; Carcinoma, Hepatocell | 2008 |
Inflammation-induced increases in dolichol synthesis and hydroxymethylglutaryl-coenzyme A reductase activity in mouse liver are prevented by a high-cholesterol diet but not by fasting.
Topics: Acetates; Acetic Acid; Animals; Chemical and Drug Induced Liver Injury; Cholesterol, Dietary; Diterp | 1984 |
Acetic acid intoxication by rectal administration.
Topics: Acetates; Acetic Acid; Acute Kidney Injury; Administration, Rectal; Chemical and Drug Induced Liver | 1994 |
Massive noninflammatory periportal liver necrosis following concentrated acetic acid ingestion.
Topics: Acetic Acid; Adult; Chemical and Drug Induced Liver Injury; Fatal Outcome; Female; Humans; Liver; Li | 2000 |
Use of zinc acetate to treat copper toxicosis in dogs.
Topics: Absorption; Acetates; Acetic Acid; Animals; Breeding; Chemical and Drug Induced Liver Injury; Copper | 1992 |
[Status of the digestive organs at late periods after poisoning by corrosive substances].
Topics: Acetates; Acetic Acid; Biliary Dyskinesia; Burns, Chemical; Chemical and Drug Induced Liver Injury; | 1990 |
Nephrotoxicity and hepatotoxicity of 1,1-dichloro-2,2-difluoroethylene in the rat. Indications for differential mechanisms of bioactivation.
Topics: Acetates; Acetic Acid; Aminooxyacetic Acid; Animals; Biotransformation; Chemical and Drug Induced Li | 1987 |