acetic-acid-(4-acetyloxy-6-7-dimethyl-5-8-dihydronaphthalen-1-yl)-ester has been researched along with Sarcoma-180* in 1 studies
1 other study(ies) available for acetic-acid-(4-acetyloxy-6-7-dimethyl-5-8-dihydronaphthalen-1-yl)-ester and Sarcoma-180
| Article | Year |
|---|---|
Some substituted naphthazarins as potential anticancer agents.
Some 2,3-bis(substituted methyl)naphthazarins and related compounds were synthesized by the Diels-Alder reaction of benzoquinone and 2,3-dimethylbutadiene followed by oxidation and substitution reactions. These compounds were prepared as potential biological alkylating agents. Screening results indicated that 1,4-diacetyl-6,7-dimethyl-4a,5,8,8a-tetrahydronaphthalene and 5,8-bis(benzoyloxy)-2,3-dimethyl-1,4-naphthoquinone possessed borderline activity against leukemia P388 and that naphthazarin diacetate possessed confirmed cytotoxicity against the cell culture of human epidermoid carcinoma of the nasopharynx. Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Leukemia L1210; Leukemia, Experimental; Mice; Naphthoquinones; Osteosarcoma; Sarcoma 180; Sarcoma, Experimental | 1976 |