Page last updated: 2024-10-22

acetazolamide and Vertigo

acetazolamide has been researched along with Vertigo in 14 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Vertigo: An illusion of movement, either of the external world revolving around the individual or of the individual revolving in space. Vertigo may be associated with disorders of the inner ear (EAR, INNER); VESTIBULAR NERVE; BRAINSTEM; or CEREBRAL CORTEX. Lesions in the TEMPORAL LOBE and PARIETAL LOBE may be associated with FOCAL SEIZURES that may feature vertigo as an ictal manifestation. (From Adams et al., Principles of Neurology, 6th ed, pp300-1)

Research Excerpts

ExcerptRelevanceReference
"Episodic ataxia type 2 is an autosomal dominant channelopathy, caused by genetic variants in the voltage-dependent calcium channel a-1 subunit (CACNA1A), which is characterized by intermittent episodes of vertigo and ataxia."5.72The efficacy of combining topiramate and 4-aminopyridine to reduce relapses and interictal progression in two cases of episodic ataxia type 2. ( Brieva-Ruiz, L; González-Mingot, C; López-Ortega, R, 2022)
"This syndrome is 1 of the few treatable causes of chronic episodic vertigo."5.28Acetazolamide-responsive vestibulocerebellar syndrome: clinical and oculographic features. ( Baloh, RW; Winder, A, 1991)
"Meniere's disease is a clinical syndrome of uncertain aetiology but it is a widespread belief that it is related to endolymphatic hydrops."2.43Hypothesis: could Meniere's disease be a channelopathy? ( Gates, P, 2005)
"Episodic ataxia type 2 is an autosomal dominant channelopathy, caused by genetic variants in the voltage-dependent calcium channel a-1 subunit (CACNA1A), which is characterized by intermittent episodes of vertigo and ataxia."1.72The efficacy of combining topiramate and 4-aminopyridine to reduce relapses and interictal progression in two cases of episodic ataxia type 2. ( Brieva-Ruiz, L; González-Mingot, C; López-Ortega, R, 2022)
"Vestibular migraine (VM) consists of recurrent episodes of vestibular symptoms that are accompanied by migraine in at least 50% of the episodes."1.56Analysis of the effectiveness of the prophylaxis of vestibular migraine depending on the diagnostic category and the prescribed drug. ( Álvarez-Morujo de Sande, MG; Bécares-Martínez, C; Domènech-Vadillo, E; Domínguez-Durán, E; González-Aguado, R; Guerra-Jiménez, G; Montilla-Ibáñez, MA, 2020)
"Acetazolamide was effective in reducing both the frequency and severity of vertigo and headache attacks and this effect was more prominent for vertigo frequency and severity."1.43Acetazolamide in vestibular migraine prophylaxis: a retrospective study. ( Bilgen, C; Çelebisoy, N; Gökçay, F; Karahan, C; Karapolat, H; Kirazlı, T; Köse, T, 2016)
"This syndrome is 1 of the few treatable causes of chronic episodic vertigo."1.28Acetazolamide-responsive vestibulocerebellar syndrome: clinical and oculographic features. ( Baloh, RW; Winder, A, 1991)
"The diagnosis of familial periodic ataxia was made from the family history and examination of the family members."1.28Familial periodic ataxia. ( Gubbay, SS; Hankey, GJ, 1989)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19906 (42.86)18.7374
1990's3 (21.43)18.2507
2000's2 (14.29)29.6817
2010's1 (7.14)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
González-Mingot, C1
López-Ortega, R1
Brieva-Ruiz, L1
Domínguez-Durán, E1
Montilla-Ibáñez, MA1
Álvarez-Morujo de Sande, MG1
Domènech-Vadillo, E1
Bécares-Martínez, C1
González-Aguado, R1
Guerra-Jiménez, G1
Çelebisoy, N1
Gökçay, F1
Karahan, C1
Bilgen, C1
Kirazlı, T1
Karapolat, H1
Köse, T1
TARLE, Y1
MONTANDON, A1
Gates, P1
Helling, K1
Scherer, H1
Jen, JC1
Yue, Q1
Karrim, J1
Nelson, SF1
Baloh, RW2
Hester, RB1
Farris, BK1
Winder, A1
Hankey, GJ1
Gubbay, SS1
Carver, RP1
Winsmann, FR1
Kiesenwetter, R1
Watanabe, Y1
Ozaki, M1
Naito, T1

Reviews

2 reviews available for acetazolamide and Vertigo

ArticleYear
Hypothesis: could Meniere's disease be a channelopathy?
    Internal medicine journal, 2005, Volume: 35, Issue:8

    Topics: Acetazolamide; Adult; Aged; Disease Progression; Endolymphatic Hydrops; Female; Genetic Predispositi

2005
[Side effects of antihypertensive therapy].
    Zeitschrift fur arztliche Fortbildung, 1970, Oct-01, Volume: 64, Issue:19

    Topics: Acetazolamide; Antihypertensive Agents; Blood Pressure; Furosemide; Humans; Hydralazine; Hydrochloro

1970

Trials

1 trial available for acetazolamide and Vertigo

ArticleYear
Effect of high elevation upon physical proficiency, cognitive functioning and subjective symptomatology.
    Perceptual and motor skills, 1968, Volume: 26, Issue:1

    Topics: Acetazolamide; Adult; Altitude; Back Pain; Cognition; Constipation; Depression; Headache; Humans; Hy

1968

Other Studies

11 other studies available for acetazolamide and Vertigo

ArticleYear
The efficacy of combining topiramate and 4-aminopyridine to reduce relapses and interictal progression in two cases of episodic ataxia type 2.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022, Volume: 43, Issue:8

    Topics: 4-Aminopyridine; Acetazolamide; Adult; Ataxia; Cerebellar Ataxia; Female; Humans; Male; Middle Aged;

2022
Analysis of the effectiveness of the prophylaxis of vestibular migraine depending on the diagnostic category and the prescribed drug.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2020, Volume: 277, Issue:4

    Topics: Acetazolamide; Amitriptyline; Analgesics; Central Nervous System Agents; Flunarizine; Humans; Migrai

2020
Acetazolamide in vestibular migraine prophylaxis: a retrospective study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:10

    Topics: Acetazolamide; Adult; Aged; Analgesics; Female; Headache; Humans; Male; Middle Aged; Migraine Disord

2016
[Treatment of labyrinthine vertigo by acetazolamide; comparative trials with chlorpromazine & heparin].
    Les Annales d'oto-laryngologie, 1957, Volume: 74, Issue:12

    Topics: Acetazolamide; Chlorpromazine; Heparin; Humans; Meniere Disease; Vertigo

1957
[THERAPEUTIC INDICATIONS IN VERTIGO AND KINETOSIS].
    Practica oto-rhino-laryngologica, 1964, Volume: 26

    Topics: Acetazolamide; Adrenal Cortex Hormones; Drug Therapy; Meniere Disease; Motion Sickness; Nystagmus, P

1964
[Vertigo attacks -- current therapy].
    Laryngo- rhino- otologie, 2005, Volume: 84, Issue:11

    Topics: Acetazolamide; Adult; Aged; Betahistine; Dexamethasone; Ear, Middle; Gentamicins; Humans; Injections

2005
Spinocerebellar ataxia type 6 with positional vertigo and acetazolamide responsive episodic ataxia.
    Journal of neurology, neurosurgery, and psychiatry, 1998, Volume: 65, Issue:4

    Topics: Acetazolamide; Adult; Aged; Anticonvulsants; Chromosome Aberrations; Chromosome Disorders; Chromosom

1998
Acetazolamide in the treatment of abnormal oculovestibular response.
    American journal of ophthalmology, 1991, Feb-15, Volume: 111, Issue:2

    Topics: Acetazolamide; Adult; Female; Humans; Male; Middle Aged; Movement; Photic Stimulation; Reflex, Abnor

1991
Acetazolamide-responsive vestibulocerebellar syndrome: clinical and oculographic features.
    Neurology, 1991, Volume: 41, Issue:3

    Topics: Acetazolamide; Adult; Cerebellar Diseases; Eye; Humans; Middle Aged; Nervous System; Oculomotor Musc

1991
Familial periodic ataxia.
    The Medical journal of Australia, 1989, Mar-06, Volume: 150, Issue:5

    Topics: Acetazolamide; Adolescent; Adult; Ataxia; Female; Humans; Periodicity; Vertigo

1989
[Case of recurrent deafness without vertigo].
    Nihon Jibiinkoka Gakkai kaiho, 1969, Volume: 72, Issue:11

    Topics: Acetazolamide; Adult; Deafness; Hearing Tests; Humans; Male; Thiamine; Vertigo

1969