Page last updated: 2024-10-22

acetazolamide and Ventricular Dysfunction, Left

acetazolamide has been researched along with Ventricular Dysfunction, Left in 2 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.

Research Excerpts

ExcerptRelevanceReference
"Acetazolamide inhibits proximal tubular sodium reabsorption and improved decongestion in the ADVOR (Acetazolamide in Decompensated Heart Failure with Volume Overload) trial."9.69Decongestion With Acetazolamide in Acute Decompensated Heart Failure Across the Spectrum of Left Ventricular Ejection Fraction: A Prespecified Analysis From the ADVOR Trial. ( Augusto, SN; Damman, K; Dauw, J; Dupont, M; Filippatos, G; Martens, P; Mebazaa, A; Meekers, E; Mullens, W; Nijst, P; Ruschitzka, F; Tang, WHW; Ter Maaten, JM; Verbrugge, FH, 2023)
"Acetazolamide inhibits proximal tubular sodium reabsorption and improved decongestion in the ADVOR (Acetazolamide in Decompensated Heart Failure with Volume Overload) trial."5.69Decongestion With Acetazolamide in Acute Decompensated Heart Failure Across the Spectrum of Left Ventricular Ejection Fraction: A Prespecified Analysis From the ADVOR Trial. ( Augusto, SN; Damman, K; Dauw, J; Dupont, M; Filippatos, G; Martens, P; Mebazaa, A; Meekers, E; Mullens, W; Nijst, P; Ruschitzka, F; Tang, WHW; Ter Maaten, JM; Verbrugge, FH, 2023)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Martens, P1
Dauw, J1
Verbrugge, FH1
Nijst, P1
Meekers, E1
Augusto, SN1
Ter Maaten, JM1
Damman, K1
Mebazaa, A1
Filippatos, G1
Ruschitzka, F1
Tang, WHW1
Dupont, M1
Mullens, W1
Mekontso Dessap, A1
Roche-Campo, F1
Kouatchet, A1
Tomicic, V1
Beduneau, G1
Sonneville, R1
Cabello, B1
Jaber, S1
Azoulay, E1
Castanares-Zapatero, D1
Devaquet, J1
Lellouche, F1
Katsahian, S1
Brochard, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Weaning of Mechanical Ventilation Guided by the Natriuretic Peptide of Type B[NCT00473148]Phase 3265 participants (Actual)Interventional2007-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for acetazolamide and Ventricular Dysfunction, Left

ArticleYear
Decongestion With Acetazolamide in Acute Decompensated Heart Failure Across the Spectrum of Left Ventricular Ejection Fraction: A Prespecified Analysis From the ADVOR Trial.
    Circulation, 2023, 01-17, Volume: 147, Issue:3

    Topics: Acetazolamide; Diuretics; Female; Heart Failure; Humans; Male; Natriuretic Peptide, Brain; Sodium Po

2023
Natriuretic peptide-driven fluid management during ventilator weaning: a randomized controlled trial.
    American journal of respiratory and critical care medicine, 2012, Dec-15, Volume: 186, Issue:12

    Topics: Acetazolamide; Aged; Diuretics; Female; Furosemide; Humans; Male; Middle Aged; Natriuretic Peptide,

2012